Tao Chen

Summary

Country: China

Publications

  1. ncbi request reprint Polyethylenimine-DNA solid particles for gene delivery
    Tao Chen
    Faculty of Life Sciences, Northwestern Polytechnical University, Shaanxi Xi an, People s Republic of China
    J Drug Target 15:714-20. 2007
  2. pmc Enhanced bactericidal potency of nanoliposomes by modification of the fusion activity between liposomes and bacterium
    Yufan Ma
    Key Laboratory for Space Bioscience and Biotechnology, School of Life Sciences, Northwestern Polytechnical University, Xi an, Shaanxi, People s Republic of China
    Int J Nanomedicine 8:2351-60. 2013
  3. doi request reprint Modification of liposomes with proteins by dansyl-labeled heterobifunctional crosslinker
    Tao Chen
    Faculty of Life Sciences, Northwestern Polytechnical University Xi an, Shaanxi 710072, PR China
    J Biomater Appl 26:117-25. 2011
  4. ncbi request reprint [Preparation and thermo-sensitivity behavior of polymer liposomes made of poly(2-ethylacrylic acid) alkylamide derivatives]
    Zhao Wang
    Faculty of Life Sciences, Northwestern Polytechnical University, Xi an 710072, China
    Yao Xue Xue Bao 43:1239-44. 2008
  5. ncbi request reprint [Construction and evaluation of non-specific targeting cationic polymer lipid liposomes]
    Tao Chen
    Faculty of Life Sciences, Northwestern Polytechnical University, Xi an 710072, China
    Yao Xue Xue Bao 45:359-64. 2010
  6. doi request reprint Iduna protects HT22 cells from hydrogen peroxide-induced oxidative stress through interfering poly(ADP-ribose) polymerase-1-induced cell death (parthanatos)
    Haoxiang Xu
    Department of Neurosurgery, Xijing Hospital, Fourth Military Medical University, Xi an, People s Republic of China
    Cell Signal 25:1018-26. 2013
  7. ncbi request reprint [Property of liposomal fusion induced by acid-sensitive polymer]
    Ru tao Wang
    Faculty of Life Sciences, Northwestern Polytechnical University, Xi an 710072, China
    Yao Xue Xue Bao 43:951-5. 2008
  8. pmc Influence of polymer size, liposomal composition, surface charge, and temperature on the permeability of pH-sensitive liposomes containing lipid-anchored poly(2-ethylacrylic acid)
    Tingli Lu
    Key Laboratory for Space Bioscience and Biotechnology, School of Life Science, Northwestern Polytechnical University, Xi an, China
    Int J Nanomedicine 7:4917-26. 2012
  9. ncbi request reprint [Acid-sensitive liposomes prepared with poly(ethylene glycol)-POPA derivatives]
    Zhao Wang
    Faculty of Life Sciences, Northwestern Polytechnical University, Xi an 710072, China
    Yao Xue Xue Bao 44:519-24. 2009
  10. doi request reprint Neurokinin-1 receptor-expressing neurons that contain serotonin and gamma-aminobutyric acid in the rat rostroventromedial medulla are involved in pain processing
    Tao Chen
    Department of Anatomy and K K Leung Brain Research Centre, The Fourth Military Medical University, Xi an, PR China
    J Pain 14:778-92. 2013

Collaborators

Detail Information

Publications45

  1. ncbi request reprint Polyethylenimine-DNA solid particles for gene delivery
    Tao Chen
    Faculty of Life Sciences, Northwestern Polytechnical University, Shaanxi Xi an, People s Republic of China
    J Drug Target 15:714-20. 2007
    ..Intraperitoneal administration of PEI-condensed DNA resulted in significant gene expression in a human ovarian cancer peritoneal xenograft model...
  2. pmc Enhanced bactericidal potency of nanoliposomes by modification of the fusion activity between liposomes and bacterium
    Yufan Ma
    Key Laboratory for Space Bioscience and Biotechnology, School of Life Sciences, Northwestern Polytechnical University, Xi an, Shaanxi, People s Republic of China
    Int J Nanomedicine 8:2351-60. 2013
    ....
  3. doi request reprint Modification of liposomes with proteins by dansyl-labeled heterobifunctional crosslinker
    Tao Chen
    Faculty of Life Sciences, Northwestern Polytechnical University Xi an, Shaanxi 710072, PR China
    J Biomater Appl 26:117-25. 2011
    ..The reliability of the fluorescence quantification was confirmed by a micro bio-barcode assay protein assay...
  4. ncbi request reprint [Preparation and thermo-sensitivity behavior of polymer liposomes made of poly(2-ethylacrylic acid) alkylamide derivatives]
    Zhao Wang
    Faculty of Life Sciences, Northwestern Polytechnical University, Xi an 710072, China
    Yao Xue Xue Bao 43:1239-44. 2008
    ..The poly (2-ethylacrylate) for the preparation of medium-induced thermal liposomes in vitro experiments showed a good thermal characteristics and the methods of preparing temperature-sensitive liposomes were convenient and stability...
  5. ncbi request reprint [Construction and evaluation of non-specific targeting cationic polymer lipid liposomes]
    Tao Chen
    Faculty of Life Sciences, Northwestern Polytechnical University, Xi an 710072, China
    Yao Xue Xue Bao 45:359-64. 2010
    ..Cell binding experiments show that cationic polymer liposomes, especially dendrimer polymer liposomes had higher local charge density, and therefore have dramatic non specific cell targeting ability...
  6. doi request reprint Iduna protects HT22 cells from hydrogen peroxide-induced oxidative stress through interfering poly(ADP-ribose) polymerase-1-induced cell death (parthanatos)
    Haoxiang Xu
    Department of Neurosurgery, Xijing Hospital, Fourth Military Medical University, Xi an, People s Republic of China
    Cell Signal 25:1018-26. 2013
    ....
  7. ncbi request reprint [Property of liposomal fusion induced by acid-sensitive polymer]
    Ru tao Wang
    Faculty of Life Sciences, Northwestern Polytechnical University, Xi an 710072, China
    Yao Xue Xue Bao 43:951-5. 2008
    ....
  8. pmc Influence of polymer size, liposomal composition, surface charge, and temperature on the permeability of pH-sensitive liposomes containing lipid-anchored poly(2-ethylacrylic acid)
    Tingli Lu
    Key Laboratory for Space Bioscience and Biotechnology, School of Life Science, Northwestern Polytechnical University, Xi an, China
    Int J Nanomedicine 7:4917-26. 2012
    ..This study aimed to identify parameters influencing the extent of contents release from poly(ethylacrylic acid) (PEAA) vesicles, focusing on the effects of polymer size, lipid composition, vesicle surface charge, and temperature...
  9. ncbi request reprint [Acid-sensitive liposomes prepared with poly(ethylene glycol)-POPA derivatives]
    Zhao Wang
    Faculty of Life Sciences, Northwestern Polytechnical University, Xi an 710072, China
    Yao Xue Xue Bao 44:519-24. 2009
    ..The acidic sensitive liposomes prepared by poly(ethylene glycol)-lipid derivatives were developed as a potential pH sensitive delivery system...
  10. doi request reprint Neurokinin-1 receptor-expressing neurons that contain serotonin and gamma-aminobutyric acid in the rat rostroventromedial medulla are involved in pain processing
    Tao Chen
    Department of Anatomy and K K Leung Brain Research Centre, The Fourth Military Medical University, Xi an, PR China
    J Pain 14:778-92. 2013
    ..The present study provides potent morphological evidence that 5-HT and GABA are coexistent in RVM-spinal cord-projecting neurons that are also regulated by SPergic projections...
  11. pmc Protective effects of SKF-96365, a non-specific inhibitor of SOCE, against MPP+-induced cytotoxicity in PC12 cells: potential role of Homer1
    Tao Chen
    Department of Neurosurgery, Xijing Institute of Clinical Neuroscience, Xijing Hospital, Fourth Military Medical University, Xi an, Shaanxi, China
    PLoS ONE 8:e55601. 2013
    ....
  12. pmc Synergy between polyethylenimine and different families of antibiotics against a resistant clinical isolate of Pseudomonas aeruginosa
    Hayssam Khalil
    Faculty of Life Sciences, Northwestern Polytechnical University, Xi an, Shaanxi 710072, People s Republic of China
    Antimicrob Agents Chemother 52:1635-41. 2008
    ..These results indicate that infections due to resistant Pseudomonas strains could be treated by the use of a synergistic combination of PEI and antimicrobial drugs...
  13. doi request reprint Preparation of amifostine polylactide-co-glycolide microspheres and its irradiation protective to mouse through oral administration
    Ting li Lu
    Key Laboratory for Space Biosciences and Biotechnology, Faculty of Life Science, Northwestern Polytechnical University, Xi an, China
    Drug Dev Ind Pharm 37:1473-80. 2011
    ..The results indicated that amifostine PLGA microsphere was more irradiation protective to mouse than that of free amifostine under the same oral administration route...
  14. doi request reprint Insulin ameliorates miR-1-induced injury in H9c2 cells under oxidative stress via Akt activation
    Tao Chen
    Department of Cardiovascular Medicine, First Affiliated Hospital of Medical School, Xi an Jiaotong University, Xi an, Shaanxi, China
    Mol Cell Biochem 369:167-74. 2012
    ..These results provide an important, novel clue as to the mechanism of the cardiovascular action of insulin...
  15. ncbi request reprint [Acid-sensitive polymer liposomes prepared by poly(2-ethylacrylic acid) alkylamide derivatives]
    Ru tao Wang
    Faculty of Life Sciences, Northwestern Polytechnical University, Xi an 710072, China
    Yao Xue Xue Bao 42:1303-8. 2007
    ..4) The PEAA-associated-liposomes shown pH-sensitive drug release property under acidic conditions. The anchored-poly (ethylacrylic acid) lipid derivatives can be useful in developing a potential pH sensitive drug delivery system...
  16. doi request reprint Neuroprotective effects of allicin on spinal cord ischemia-reperfusion injury via improvement of mitochondrial function in rabbits
    Jin Wen Zhu
    Institute of Orthopaedics and Traumatology, Xijing Hospital, Fourth Military Medical University, Xi an, Shaanxi Province 710032, PR China
    Neurochem Int 61:640-8. 2012
    ..Collectively, these findings demonstrated that allicin exerts neuroprotection against spinal cord I/R injury in rabbits, which may be associated with the improvement of mitochondrial function...
  17. doi request reprint Synthesis and in vivo bioactivity of lipophilic alendronate derivatives against osteoporosis
    Ting li Lu
    Key Laboratory for Space Biosciences and Biotechnology, Faculty of Life Science, Northwestern Polytechnical University, Xi an, China
    Drug Dev Ind Pharm 37:656-63. 2011
    ....
  18. pmc Pharmacological rescue of cortical synaptic and network potentiation in a mouse model for fragile x syndrome
    Tao Chen
    1 Center for Neuron and Disease, Frontier Institute of Science and Technology, Xi an Jiaotong University, Xi an, China 2 Department of Anatomy and KK Leung Brain Research Center, Fourth Military Medical University, Xi an, China
    Neuropsychopharmacology 39:1955-67. 2014
    ..This study is the first report of the network properties of L-LTP in the ACC, and provides basic mechanisms for future treatment of cortex-related cognitive defects in fragile X patients. ..
  19. doi request reprint Protective effect of Homer 1a against hydrogen peroxide-induced oxidative stress in PC12 cells
    Peng Luo
    Department of Neurosurgery, Xijing Hospital, Fourth Military Medical University, Xi an, PR China
    Free Radic Res 46:766-76. 2012
    ....
  20. pmc Techniques for fabrication and construction of three-dimensional scaffolds for tissue engineering
    Tingli Lu
    Key Laboratory of Space Bioscience and Biotechnology, School of Life Science, Northwestern Polytechnical University, Xi an, China
    Int J Nanomedicine 8:337-50. 2013
    ..Finally, perspectives on future development of the bottom-up approach for tissue engineering are addressed...
  21. doi request reprint Visual signal pathway reorganization in the Cacna1f mutant rat model
    Ye Tao
    Department of Clinical Aerospace Medicine, Fourth Military Medical University, Xi an, People s Republic of China
    Invest Ophthalmol Vis Sci 54:1988-97. 2013
    ..To elucidate the underlying pathologic mechanism of congenital stationary night blindness (CSNB) by examining the characteristics of electrical signal transmission within the inner retinal circuit after Cacna1f gene mutation...
  22. pmc Acute colitis induces neurokinin 1 receptor internalization in the rat lumbosacral spinal cord
    Ming Ming Zhang
    Department of Anatomy, Histology, Embryology and K K Leung Brain Research Centre, The Fourth Military Medical University, Xi an, PR China
    PLoS ONE 8:e59234. 2013
    ..The present results suggest that the visceral nociceptive information arising from inflamed pelvic organs, such as the lower colon, might be mediated by the NK1R-ir neurons in the DCN of the lumbosacral spinal cord...
  23. ncbi request reprint 4-Aminobiphenyl induces liver DNA adducts in both neonatal and adult mice but induces liver mutations only in neonatal mice
    Tao Chen
    Division of Genetic and Reproductive Toxicology, U S Food and Drug Administration, National Center for Toxicological Research, Jefferson, AR 72079, USA
    Int J Cancer 117:182-7. 2005
    ..Supplementary material for this article can be found on the International Journal of Cancer website at http://www.interscience.wiley.com/jpages/0020-7136/suppmat/index.html..
  24. ncbi request reprint 3'-azido-3'-deoxythymidine induces deletions in L5178Y mouse lymphoma cells
    Jianyong Wang
    Department of Pharmacology and Toxicology, University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA
    Environ Mol Mutagen 48:248-57. 2007
    ..Our data indicate that AZT primarily induced LOH mutations in L5178Y mouse lymphoma cells and a large number of LOH mutations resulted from deletions...
  25. pmc A novel ARID DNA-binding protein interacts with SymRK and is expressed during early nodule development in Lotus japonicus
    Hui Zhu
    State Key Laboratory of Agricultural Microbiology, Huazhong Agricultural University, Wuhan 430070, China
    Plant Physiol 148:337-47. 2008
    ..It is proposed that SIP1 may be required for the expression of NIN and involved in the initial communications between the rhizobia and the host root cells...
  26. pmc Investigation of transcriptional gene silencing and mechanism induced by shRNAs targeted to RUNX3 in vitro
    Xue Zhi Feng
    Cancer Research Institute, Nanhua University of South China, Hengyang 421001, Hunan Province, China
    World J Gastroenterol 14:3006-14. 2008
    ..To investigate transcriptional gene silencing induced by short hairpin RNAs (shRNAs) that target gene prompter regions of RUNX3 gene, and whether shRNAs homologous to DNA sequences may serve as initiators for methylation...
  27. ncbi request reprint Different fates of donor mitochondrial DNA in bovine-rabbit and cloned bovine-rabbit reconstructed embryos during preimplantation development
    Yan Jiang
    State Key Laboratory of Reproductive Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing 100080, China
    Front Biosci 11:1425-32. 2006
    ..Our results demonstrate that: 1) the fates of donor mtDNAs in bovine-rabbit and cloned bovine-rabbit reconstructed embryos were different; and 2) recipient mtDNAs replicate at blastocyst regardless of the difference of donor cells...
  28. ncbi request reprint Design of recombinant stem cell factor-macrophage colony stimulating factor fusion proteins and their biological activity in vitro
    Tao Chen
    School of Life Science and State Key Laboratory of Pharmaceutical Biotechnology, Nanjing University, 210093, Nanjing, People s Republic of China
    J Comput Aided Mol Des 19:319-28. 2005
    ....
  29. ncbi request reprint DNA hypomethylation of individual sequences in aborted cloned bovine fetuses
    Tao Chen
    State Key Laboratory of Reproductive Biology, Institute of Zoology, Chinese Academy of Science, Beijing 100080, China
    Front Biosci 10:3002-8. 2005
    ..These findings suggest that aberrant DNA methylation may contribute to the developmental failure of cloned bovine fetuses...
  30. ncbi request reprint Variations of very low-density lipoprotein receptor subtype expression in gastrointestinal adenocarcinoma cells with various differentiations
    Tao Chen
    Department of Biochemistry and Molecular Biology, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, Hubei Province, China
    World J Gastroenterol 11:2817-21. 2005
    ..This study is aimed at investigating the expression and possible significances of very low-density lipoprotein receptor (VLDLR) subtypes in gastroenteric adenocarcinoma tissues and cells with various differentiations...
  31. ncbi request reprint Expression of a novel recombinant stem cell factor/macrophage colony-stimulating factor fusion protein in baculovirus-infected insect cells
    Tao Chen
    School of Life Science and State Key Laboratory of Pharmaceutical Biotechnology, Nanjing University, Nanjing 210093, PR China
    Protein Expr Purif 41:402-8. 2005
    ....
  32. ncbi request reprint N-ethyl-N-nitrosourea (ENU) increased brain mutations in prenatal and neonatal mice but not in the adults
    William Slikker
    College of Letters and Science, University of California, Los Angeles 90024, USA
    Toxicol Sci 81:112-20. 2004
    ..These results demonstrate a differential mutagenic effect of ENU on the mouse brain depending on the stages of development and suggest an enhanced susceptibility of brain cancer hazard for perinatal exposure to genotoxicants...
  33. ncbi request reprint [Apoptosis in hepatoma cells induced by antisense oligodeoxynucleotide against survivin]
    Tao Chen
    Center of General Surgery, General Hospital of Chengdu Region, Chengdu 610083, China
    Zhonghua Gan Zang Bing Za Zhi 11:546-9. 2003
    ..To investigate the apoptosis induced by antisense oligodeoxynucleotide (ASODN) against survivin and the mechanisms after the hepatocellular carcinoma SMMC-7721 cells transfected with the ASODN...
  34. ncbi request reprint [The signal transduction pathway related to hepatocellular carcinoma apoptosis induced by survivin antisense oligonucleotide]
    Tao Chen
    Center of General Surgery, General Hospital of Chengdu Command, Chengdu 610083 China
    Zhonghua Yi Xue Za Zhi 83:425-9. 2003
    ..The expression of survivin gene in hepatocellular carcinoma cell line SMMC-7721 was blocked by means of antisense oligonucleotide (ASODN) transfection. To investigate the signal transduction pathway of apoptosis induced by survivin ASODN...
  35. ncbi request reprint Mutagenicity of bromate: implications for cancer risk assessment
    Martha M Moore
    Division of Genetic and Reproductive Toxicology, National Center for Toxicological Research, FDA, HFT 120, NCTR, 3900 NCTR Rd, Jefferson, AR 72079, USA
    Toxicology 221:190-6. 2006
    ..However, in the absence of additional information, it is reasonable, based on an extensive database, to assume that bromate induces tumors via oxidative damage that causes chromosomal breakage...
  36. ncbi request reprint Murine B16 melanomas expressing high levels of the chemokine stromal-derived factor-1/CXCL12 induce tumor-specific T cell chemorepulsion and escape from immune control
    Fabrizio Vianello
    Partners AIDS Research Center, Infectious Diseases Division, and Massachusetts General Hospital Cancer Center, Charlestown, MA 02129, USA
    J Immunol 176:2902-14. 2006
    ..The repulsion of tumor Ag-specific T cells away from melanomas expressing CXCL12 confirms the chemorepellent activity of high concentrations of CXCL12 and may represent a novel mechanism by which certain tumors evade the immune system...
  37. pmc The peripheral benzodiazepine receptor ligand 1-(2-chlorophenyl-methylpropyl)-3-isoquinoline-carboxamide is a novel antagonist of human constitutive androstane receptor
    Linhao Li
    Department of Pharmaceutical Sciences, School of Pharmacy, University of Maryland at Baltimore, 20 Penn Street, Baltimore, MD 21201, USA
    Mol Pharmacol 74:443-53. 2008
    ..Thus, PK11195 can be used as a chemical tool for studying the molecular basis of CAR function...
  38. doi request reprint Inhibitory effect of siRNA targeting survivin in gastric cancer MGC-803 cells
    Tao Chen
    Gastroenterology Department of Zhongnan Hospital, Wuhan University, East Lake Road, Hubei Province, PR China
    Int Immunopharmacol 8:1006-11. 2008
    ..05). In summary, siRNA targeting of survivin can effectively inhibit the growth of gastric cancer cells and may be used as a potent therapy...
  39. ncbi request reprint BRI3 associates with SCG10 and attenuates NGF-induced neurite outgrowth in PC12 cells
    Yanhua Gong
    National Laboratory of Medical Molecular Biology, Institute of Basic Medical Science, Chinese Academy of Medical Sciences and Peking Union Medical College, National Human Genome Center, Beijing, China
    BMB Rep 41:287-93. 2008
    ..These results identify a novel connection between a neuron-specific BRI protein and the cytoskeletal network, suggesting possible roles of BRI3 in the process of neuronal differentiation...
  40. ncbi request reprint Functional characterization of artemin, a ferritin homolog synthesized in Artemia embryos during encystment and diapause
    Tao Chen
    Department of Biology, Dalhousie University, Halifax, NS, Canada
    FEBS J 274:1093-101. 2007
    ..Therefore, because artemin accumulates abundantly during development, it has the potential to protect embryos from stress during encystment and diapause without adversely affecting iron metabolism...
  41. ncbi request reprint Selective expression of Bhlhb5 in subsets of early-born interneurons and late-born association neurons in the spinal cord
    Ben Liu
    The National Laboratory of Medical Molecular Biology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China
    Dev Dyn 236:829-35. 2007
    ..At late stages of development, Bhlhb5 expression is detected in a subset of late-born dorsal association interneurons that migrate into the uppermost layer of the dorsal horn...
  42. ncbi request reprint Photomutagenicity of anhydroretinol and 5,6-epoxyretinyl palmitate in mouse lymphoma cells
    Nan Mei
    Division of Genetic, National Center for Toxicological Research, U S Food and Drug Administration, Jefferson, Arkansas 72079, USA
    Chem Res Toxicol 19:1435-40. 2006
    ..These results suggest that two of RP's photodecomposition products are photomutagenic in mouse lymphoma cells, causing events that affect a large segment of the chromosome...
  43. ncbi request reprint Redirection electron flow to high coupling efficiency of terminal oxidase to enhance riboflavin biosynthesis
    Xiao Jing Li
    School of Chemical Engineering and Technology, Tianjin University, Tianjin 300072, People s Republic of China
    Appl Microbiol Biotechnol 73:374-83. 2006
    ..The higher product-corrected biomass yield in mutant showed that the efficient energy generation is an important factor for exponential growth of riboflavin overproducing B. subtilis strain in batch culture...
  44. ncbi request reprint [Effect of recombinant human growth hormone on growth of human Bel-7402 hepatic carcinoma xenografts in nude mice]
    Jian Ping Liu
    Department of General Surgery, The Second Affiliated Hospital, Sun Yat Sen University, Guangzhou, Guangdong 510120, P R China
    Ai Zheng 25:292-6. 2006
    ..Because most primary hepatic carcinoma could express human growth hormone receptor (GHR), this study was to explore the effects of rhGH on the growth of human Bel-7402 hepatic carcinoma (with GHR expression) xenograft in nude mice...
  45. ncbi request reprint Transfection properties of stabilized plasmid-lipid particles containing cationic PEG lipids
    Lorne R Palmer
    Department of Biochemistry and Molecular Biology, University of British Columbia, 2146 Health Sciences Mall, Vancouver, BC, Canada V6T 1Z3
    Biochim Biophys Acta 1611:204-16. 2003
    ..It is concluded that in the presence of Ca(2+) and appropriate ligands to stimulate uptake, SPLP are highly potent transfection agents...