Juan Carlos Araya

Summary

Affiliation: Universidad de La Frontera
Country: Chile

Publications

  1. ncbi [Promoter methylation profile in gastric cancer]
    Juan Carlos Roa
    Departamento de Anatomia Patologica, Universidad de La Frontera, Temuco, Chile
    Rev Med Chil 133:874-80. 2005
  2. ncbi [Point mutation of TP53 suppressor gene in pre-neoplastic and neoplastic lesions of the stomach]
    Juan Carlos Araya
    Departamento de Anatomia Patologica, Facultad de Medicina, Universidad de La Frontera, Casilla 54 D, Temuco, Chile
    Rev Med Chil 131:359-65. 2003
  3. ncbi [Association between Helicobacter pylori genotype and the severity of gastritis in infected adults]
    Juan Carlos Araya
    Departamentos de Anatomía Patològica y de Medicina Interna, Facultad de Medicina, Universidad de La Frontera, Temuco, Chile
    Rev Med Chil 132:1345-54. 2004
  4. ncbi Promoter methylation profile in gallbladder cancer
    Juan Carlos Roa
    Department of Pathology, Faculty of Medicine, Universidad de La Frontera, Manuel Montt 112, Temuco, 478 1176, Chile
    J Gastroenterol 41:269-75. 2006
  5. ncbi [Genetic changes in chronic gastritis: study of microsatellite instability and loss of heterozygosity]
    Juan Carlos Roa
    Departamento de Anatomia Patologica, Facultad de Medicina, Universidad de La Frontera, Temuco, Chile
    Rev Med Chil 131:1365-74. 2003
  6. ncbi [Inactivation of CDKN2A gene (p16) in gallbladder carcinoma]
    Juan Carlos Roa
    Departamento de Anatomá Patológica, Universidad de La Frontera, Temuco, Chile
    Rev Med Chil 132:1369-76. 2004
  7. doi Promoter methylation profile in preneoplastic and neoplastic gallbladder lesions
    Patricia Garcia
    Department of Pathology, Universidad de La Frontera, Temuco, Chile
    Mol Carcinog 48:79-89. 2009
  8. ncbi Microsatellite instability in preneoplastic and neoplastic lesions of the gallbladder
    Juan Carlos Roa
    Department of Pathology, Universidad de La Frontera, Faculty of Medicine, Manuel Montt 112, Temuco, Chile
    J Gastroenterol 40:79-86. 2005
  9. doi [Prognostic factors for gastric cancer without lymph node involvement]
    Oscar Tapia
    Departamento de Anatomia Patologica, Facultad de Medicina, Universidad de La Frontera, Temuco, Chile
    Rev Med Chil 139:432-8. 2011
  10. ncbi [Microsatellite instability and loss of heterozygosity in neoplastic and preneoplastic gastric lesions]
    Juan Carlos Roa
    Departamento de Patologia, Universidad de La Frontera, Temuco, Chile
    Rev Med Chil 131:1227-36. 2003

Collaborators

  • Ivan Roa
  • Oscar Tapia
  • Barbara G Schneider
  • P Correa
  • Carlos Manterola
  • Héctor Losada M
  • Juan Carlos Roa
  • Miguel Villaseca
  • Pablo Guzman
  • Ismael Riquelme
  • Leonardo Anabalón
  • Patricia Garcia
  • Sergio Munoz
  • Angélica Melo
  • Quynh Vo
  • Pamela Leal
  • Richard M Peek
  • Jaime A Espinoza
  • Carolina Bizama
  • Alejandra Sandoval
  • Kurt Buchegger
  • Miguel Angel Villaseca
  • Hector Alvarez
  • Melanie Thomas
  • Antonio Sanhueza
  • Enrique Contreras
  • Xavier de Aretxabala
  • Paula Carrasco
  • Xabier de Aretxabala
  • Javier Martinez
  • Gilda S Ibacache

Detail Information

Publications16

  1. ncbi [Promoter methylation profile in gastric cancer]
    Juan Carlos Roa
    Departamento de Anatomia Patologica, Universidad de La Frontera, Temuco, Chile
    Rev Med Chil 133:874-80. 2005
    ..This genetic-molecular pathway for cancer may separate a subset of patients with different prognoses and eventually different responses to specific therapies...
  2. ncbi [Point mutation of TP53 suppressor gene in pre-neoplastic and neoplastic lesions of the stomach]
    Juan Carlos Araya
    Departamento de Anatomia Patologica, Facultad de Medicina, Universidad de La Frontera, Casilla 54 D, Temuco, Chile
    Rev Med Chil 131:359-65. 2003
    ..In the current model for the development of gastric cancer, regions of multifocal atrophic gastritis give rise to intestinal metaplasia, dysplasia and finally, adenocarcinoma...
  3. ncbi [Association between Helicobacter pylori genotype and the severity of gastritis in infected adults]
    Juan Carlos Araya
    Departamentos de Anatomía Patològica y de Medicina Interna, Facultad de Medicina, Universidad de La Frontera, Temuco, Chile
    Rev Med Chil 132:1345-54. 2004
    ..The damaging capacity of Helicobacter pylori is variable and depends, in part, on its genetic polymorphism...
  4. ncbi Promoter methylation profile in gallbladder cancer
    Juan Carlos Roa
    Department of Pathology, Faculty of Medicine, Universidad de La Frontera, Manuel Montt 112, Temuco, 478 1176, Chile
    J Gastroenterol 41:269-75. 2006
    ..Our objective was to analyze the methylation pattern of some of the genes involved in carcinogenesis of the gallbladder, examining the immunohistochemical expression of proteins, clinical features, and patient survival time...
  5. ncbi [Genetic changes in chronic gastritis: study of microsatellite instability and loss of heterozygosity]
    Juan Carlos Roa
    Departamento de Anatomia Patologica, Facultad de Medicina, Universidad de La Frontera, Temuco, Chile
    Rev Med Chil 131:1365-74. 2003
    ..Multifocal chronic gastritis, associated to intestinal metaplasia, is considered a preneoplastic lesion, closely associated to intestinal type gastric cancer...
  6. ncbi [Inactivation of CDKN2A gene (p16) in gallbladder carcinoma]
    Juan Carlos Roa
    Departamento de Anatomá Patológica, Universidad de La Frontera, Temuco, Chile
    Rev Med Chil 132:1369-76. 2004
    ..The CDKN2A gene encodes a cyclin dependent kinase inhibitor, p16, which promotes cell cycle arrest. Methylation of the promoter region transcriptionally inactivates the gene...
  7. doi Promoter methylation profile in preneoplastic and neoplastic gallbladder lesions
    Patricia Garcia
    Department of Pathology, Universidad de La Frontera, Temuco, Chile
    Mol Carcinog 48:79-89. 2009
    ..Finally, the methylation status of some individual genes could be useful biomarkers with potential clinical application in diagnosis or prognosis of GBC if they are validated in a greater number of clinical samples...
  8. ncbi Microsatellite instability in preneoplastic and neoplastic lesions of the gallbladder
    Juan Carlos Roa
    Department of Pathology, Universidad de La Frontera, Faculty of Medicine, Manuel Montt 112, Temuco, Chile
    J Gastroenterol 40:79-86. 2005
    ..Our findings were then correlated with clinicopathological variables and survival time...
  9. doi [Prognostic factors for gastric cancer without lymph node involvement]
    Oscar Tapia
    Departamento de Anatomia Patologica, Facultad de Medicina, Universidad de La Frontera, Temuco, Chile
    Rev Med Chil 139:432-8. 2011
    ..The absence of lymph node involvement (N0) in gastric cancer is associated with a better survival. However some N0 gastric tumors still have a bad prognosis...
  10. ncbi [Microsatellite instability and loss of heterozygosity in neoplastic and preneoplastic gastric lesions]
    Juan Carlos Roa
    Departamento de Patologia, Universidad de La Frontera, Temuco, Chile
    Rev Med Chil 131:1227-36. 2003
    ..7 per 105 in males in the IX region. A chain of genetic and morphological events precedes the intestinal type of gastric carcinoma. One of them is the called multifocal atrophic gastritis often associated with intestinal metaplasia...
  11. doi [Concordance between Gleason scores of trans rectal biopsies and the surgical piece of radical prostatectomy]
    Oscar Tapia
    Departamento de Anatomia Patologica, Facultad de Medicina, Universidad de La Frontera, Temuco, Chile
    Rev Med Chil 139:171-6. 2011
    ..Gleason pathological score in prostate cancer is an important prognostic indicator. However, the concordance between the score of trans rectal needle biopsies and the final score of the surgical piece may be variable...
  12. ncbi [Promoter methylation profile in breast cancer]
    Juan Carlos Roa
    Departamento de Anatomia Patologica, Facultad de Medicina, Universidad de La Frontera, Temuco, Chile
    Rev Med Chil 132:1069-77. 2004
    ..Genomic DNA methylation, mutations and allelic deletions explain the inactivation of genes involved in cell proliferation and cell cycle control mechanisms...
  13. ncbi Prognostic factors of phyllodes tumor of the breast
    Juan Carlos Roa
    Department of Pathology, Universidad de La Frontera, Temuco, Chile
    Pathol Int 56:309-14. 2006
    ..00001) were prognostic factors of poor survival. Tumoral grade and some clinical-morphological characteristics of patients with phyllodes tumors have a significant impact on the prediction of its biological behavior...
  14. doi The Gene Expression Status of the PI3K/AKT/mTOR Pathway in Gastric Cancer Tissues and Cell Lines
    Ismael Riquelme
    Laboratory of Molecular Pathology, Department of Pathological Anatomy, School of Medicine, Universidad de La Frontera, Avenida Alemania 0458, Postal Code, 4810296, Temuco, Chile
    Pathol Oncol Res 22:797-805. 2016
    ..This is the first time this extensive panel of 9 genes within PI3K/AKT/mTOR pathway has been studied in GC to clarify the biological role of this pathway in GC and develop new strategies for this malignancy. ..
  15. doi [Mesenteric cryptococcal lymphadenitis: report of one case]
    Oscar Tapia
    Departamento de Anatomia Patologica, Facultad de Medicina, Universidad de La Frontera, Temuco, Chile
    Rev Med Chil 138:1535-8. 2010
    ..The conglomerated lymph nodes and the appendix were excised. The pathological study of the surgical piece revealed an intra abdominal cryptococcal lymphadenitis and a normal appendix...
  16. ncbi [Hepatocarcinoma with sarcomatoid transformation: case report]
    Héctor Losada M
    Departamento de Cirugía y Traumatología, Universidad de La Frontera, Temuco, Chile
    Rev Med Chil 135:768-72. 2007
    ..The pathological study of the surgical piece disclosed a hepatocarcinoma with sarcomatoid transformation. The patient was discharged sixteen days after surgery...