M Suwalsky

Summary

Country: Chile

Publications

  1. ncbi request reprint Effects of Thimerosal on Lipid Bilayers and Human Erythrocytes: An In Vitro Study
    Mario Suwalsky
    Faculty of Chemical Sciences, University of Concepcion, Concepcion, Chile
    J Membr Biol 249:823-831. 2016
  2. ncbi request reprint Antioxidant Capacity of Gallic Acid in vitro Assayed on Human Erythrocytes
    Mario Suwalsky
    Faculty of Chemical Sciences, University of Concepcion, Concepcion, Chile
    J Membr Biol 249:769-779. 2016
  3. doi request reprint Morphological Effects and Antioxidant Capacity of Solanum crispum (Natre) In Vitro Assayed on Human Erythrocytes
    Mario Suwalsky
    Faculty of Chemical Sciences, University of Concepcion, Concepcion, Chile
    J Membr Biol 249:349-61. 2016
  4. doi request reprint An in vitro study on the antioxidant capacity of usnic acid on human erythrocytes and molecular models of its membrane
    M Suwalsky
    Faculty of Chemical Sciences, University of Concepcion, Concepcion, Chile Electronic address
    Biochim Biophys Acta 1848:2829-38. 2015
  5. doi request reprint Morphological Effects Induced In Vitro by Propranolol on Human Erythrocytes
    Mario Suwalsky
    Faculty of Chemical Sciences, University of Concepcion, Concepcion, Chile
    J Membr Biol 248:683-93. 2015
  6. doi request reprint Interactions of the antiviral and antiparkinson agent amantadine with lipid membranes and human erythrocytes
    Mario Suwalsky
    Faculty of Chemical Sciences, University of Concepcion, Concepcion, Chile Electronic address
    Biophys Chem 202:13-20. 2015
  7. doi request reprint Antioxidant capacity of Ugni molinae fruit extract on human erythrocytes: an in vitro study
    Mario Suwalsky
    Faculty of Chemical Sciences, University of Concepcion, Concepcion, Chile
    J Membr Biol 247:703-12. 2014
  8. doi request reprint Acetylsalicylic acid (aspirin) and salicylic acid interaction with the human erythrocyte membrane bilayer induce in vitro changes in the morphology of erythrocytes
    Mario Suwalsky
    Faculty of Chemical Sciences, University of Concepcion, Concepcion, Chile Electronic address
    Arch Biochem Biophys 539:9-19. 2013
  9. doi request reprint Human erythrocytes and neuroblastoma cells are in vitro affected by sodium orthovanadate
    M Suwalsky
    Faculty of Chemical Sciences, University of Concepcion, Concepcion, Chile
    Biochim Biophys Acta 1818:2260-70. 2012
  10. doi request reprint Effects of sodium metavanadate on in vitro neuroblastoma and red blood cells
    Mario Suwalsky
    Faculty of Chemical Sciences, University of Concepcion, P O Box 160 C, Concepcion, Chile
    Arch Biochem Biophys 535:248-56. 2013

Detail Information

Publications67

  1. ncbi request reprint Effects of Thimerosal on Lipid Bilayers and Human Erythrocytes: An In Vitro Study
    Mario Suwalsky
    Faculty of Chemical Sciences, University of Concepcion, Concepcion, Chile
    J Membr Biol 249:823-831. 2016
    ..However, concentrations were considerable higher than those present in vaccines...
  2. ncbi request reprint Antioxidant Capacity of Gallic Acid in vitro Assayed on Human Erythrocytes
    Mario Suwalsky
    Faculty of Chemical Sciences, University of Concepcion, Concepcion, Chile
    J Membr Biol 249:769-779. 2016
    ..As a conclusion, GA would be capable to block the access of oxidants into the lipid bilayer, and thus avoid their access into red cells...
  3. doi request reprint Morphological Effects and Antioxidant Capacity of Solanum crispum (Natre) In Vitro Assayed on Human Erythrocytes
    Mario Suwalsky
    Faculty of Chemical Sciences, University of Concepcion, Concepcion, Chile
    J Membr Biol 249:349-61. 2016
    ..crispum neutralized the oxidative capacity of HClO on DMPE bilayers; defocusing microscopy and hemolysis assays demonstrated the protective effect of S. crispum against the oxidant effects of HClO on human erythrocytes. ..
  4. doi request reprint An in vitro study on the antioxidant capacity of usnic acid on human erythrocytes and molecular models of its membrane
    M Suwalsky
    Faculty of Chemical Sciences, University of Concepcion, Concepcion, Chile Electronic address
    Biochim Biophys Acta 1848:2829-38. 2015
    ....
  5. doi request reprint Morphological Effects Induced In Vitro by Propranolol on Human Erythrocytes
    Mario Suwalsky
    Faculty of Chemical Sciences, University of Concepcion, Concepcion, Chile
    J Membr Biol 248:683-93. 2015
    ..Results indicated that propranolol induced morphological changes to human erythrocytes and interacted in a concentration-dependent manner with phospholipid bilayer. ..
  6. doi request reprint Interactions of the antiviral and antiparkinson agent amantadine with lipid membranes and human erythrocytes
    Mario Suwalsky
    Faculty of Chemical Sciences, University of Concepcion, Concepcion, Chile Electronic address
    Biophys Chem 202:13-20. 2015
    ..Results indicated that amantadine induced morphological changes to human erythrocytes and interacted in a concentration-dependent manner with DMPC bilayers in contrast to DMPE that was hardly affected by the presence of the drug. ..
  7. doi request reprint Antioxidant capacity of Ugni molinae fruit extract on human erythrocytes: an in vitro study
    Mario Suwalsky
    Faculty of Chemical Sciences, University of Concepcion, Concepcion, Chile
    J Membr Biol 247:703-12. 2014
    ..molinae components into the membrane outer monolayer might hinder the diffusion of HClO and of free radicals into cell membranes and the consequent decrease of the kinetics of free radical reactions...
  8. doi request reprint Acetylsalicylic acid (aspirin) and salicylic acid interaction with the human erythrocyte membrane bilayer induce in vitro changes in the morphology of erythrocytes
    Mario Suwalsky
    Faculty of Chemical Sciences, University of Concepcion, Concepcion, Chile Electronic address
    Arch Biochem Biophys 539:9-19. 2013
    ..Results indicated that both salicylates interact with human erythrocytes and their molecular models in a concentration-dependent manner perturbing their bilayer structures...
  9. doi request reprint Human erythrocytes and neuroblastoma cells are in vitro affected by sodium orthovanadate
    M Suwalsky
    Faculty of Chemical Sciences, University of Concepcion, Concepcion, Chile
    Biochim Biophys Acta 1818:2260-70. 2012
    ..Additional experiments were performed in mice cholinergic neuroblastoma SN56 cells; a statistically significant decrease of cell viability was observed on orthovanadate in low or moderate concentrations...
  10. doi request reprint Effects of sodium metavanadate on in vitro neuroblastoma and red blood cells
    Mario Suwalsky
    Faculty of Chemical Sciences, University of Concepcion, P O Box 160 C, Concepcion, Chile
    Arch Biochem Biophys 535:248-56. 2013
    ..Also, partly unsaturated lipids could interact differently the fully saturated chains in the model systems...
  11. ncbi request reprint Protective effect of Ugni molinae Turcz against oxidative damage of human erythrocytes
    M Suwalsky
    Faculty of Chemical Sciences, University of Concepcion, Casilla 160 C, Concepcion, Chile
    Food Chem Toxicol 45:130-5. 2007
    ..This conclusion can also imply that this restriction could apply to the diffusion of free radicals into cell membranes and the subsequent decrease of the kinetics of free radical reactions...
  12. ncbi request reprint Effects of the antiepileptic drug carbamazepine on human erythrocytes
    Mario Suwalsky
    Faculty of Chemical Sciences, University of Concepcion, Casilla 160 C, Concepcion, Chile
    Toxicol In Vitro 20:1363-9. 2006
    ..This is the first time that toxic effects of carbamazepine on the human erythrocyte membrane have been described...
  13. ncbi request reprint Human erythrocytes are affected in vitro by extracts of Ugni molinae leaves
    M Suwalsky
    Faculty of Chemical Sciences, University of Concepcion, Casilla 160 C, Concepcion, Chile
    Food Chem Toxicol 44:1393-8. 2006
    ....
  14. ncbi request reprint Effects of lithium on the human erythrocyte membrane and molecular models
    Mario Suwalsky
    Faculty of Chemical Sciences, University of Concepcion, Concepcion, Chile
    Biophys Chem 129:36-42. 2007
    ....
  15. ncbi request reprint The antiepileptic drug carbamazepine affects sodium transport in toad epithelium
    Mario Suwalsky
    Department of Polymers, Faculty of Chemical Sciences, University of Concepcion, E Larenas 129, Casilla 160 C, Concepcion, Chile
    Toxicol In Vitro 20:891-8. 2006
    ..6 mM CBZ decreased Na+ mucosa-serosa flux by 19%, a result in agreement with the finding that higher concentrations of CBZ applied to the inner surface not only decreased ENa but also sodium conductance (GNa)...
  16. ncbi request reprint The antiepileptic drug phenytoin affects sodium transport in toad epithelium
    Mario Suwalsky
    Faculty of Chemical Sciences, University of Concepcion, Casilla 160 C, Concepcion, Chile
    Comp Biochem Physiol C Toxicol Pharmacol 142:253-61. 2006
    ....
  17. ncbi request reprint Effects of cadmium on Na+ transport in the isolated skin of the toad Pleurodema thaul
    M Suwalsky
    Department of Polymers, Faculty of Chemical Sciences, University of Concepcion, E Larenas 129, Casilla 160 C, Concepcion, Chile
    J Inorg Biochem 99:2362-71. 2005
    ....
  18. ncbi request reprint A study of the perturbation effects of the local anesthetic procaine on human erythrocyte and model membranes and of modifications of the sodium transport in toad skin
    Mario Suwalsky
    Faculty of Chemical Sciences, University of Concepcion, Casilla 160 C, Concepcion, Chile
    Biophys Chem 116:227-35. 2005
    ....
  19. doi request reprint Structural effects in vitro of the anti-inflammatory drug diclofenac on human erythrocytes and molecular models of cell membranes
    Mario Suwalsky
    University of Concepcion, Chile
    Biophys Chem 141:34-40. 2009
    ..This is the first time in which structural effects of diclofenac on the human erythrocyte membrane have been described...
  20. ncbi request reprint Human erythrocytes are affected by the organochloride insecticide chlordane
    M Suwalsky
    Faculty of Chemical Sciences, Department of Polymers, University of Concepcion, Casilla 160 C, Concepcion, Chile
    Food Chem Toxicol 43:647-54. 2005
    ..On the other hand, the bilayer structure of DMPE was perturbed in a fashion similar to that observed by X-ray diffraction in DMPC, a fact that explains the morphological change induced by chlordane to the human erythrocytes...
  21. ncbi request reprint Monomethylarsonate (MMAv) exerts stronger effects than arsenate on the structure and thermotropic properties of phospholipids bilayers
    Mario Suwalsky
    Faculty of Chemical Sciences, University of Concepcion, Concepcion, Chile
    Biophys Chem 132:1-8. 2008
    ....
  22. doi request reprint Cr(III) exerts stronger structural effects than Cr(VI) on the human erythrocyte membrane and molecular models
    M Suwalsky
    Faculty of Chemical Sciences, University of Concepcion, Casilla 160 C, Concepcion, Chile
    J Inorg Biochem 102:842-9. 2008
    ..In all these systems, it was found that Cr(III) induced considerably higher structural perturbations than Cr(VI)...
  23. ncbi request reprint Interaction of the anticancer drug tamoxifen with the human erythrocyte membrane and molecular models
    M Suwalsky
    Faculty of Chemical Sciences, University of Concepcion, Chile
    Z Naturforsch C 53:182-90. 1998
    ..Given the fact that tamoxifen did not interact with DMPE, it is concluded that it interacted with a protein located in the cytoplasmic moiety of the erythrocyte membrane...
  24. doi request reprint Effects of phenylpropanolamine (PPA) on in vitro human erythrocyte membranes and molecular models
    Mario Suwalsky
    Faculty of Chemical Sciences, University of Concepcion, Concepcion, Chile
    Biochem Biophys Res Commun 406:320-5. 2011
    ..1-0.5 mM range induced increasing structural perturbation to DMPC, but no effects on DMPE multibilayers were detected...
  25. doi request reprint Human erythrocytes and neuroblastoma cells are affected in vitro by Au(III) ions
    Mario Suwalsky
    Faculty of Chemical Sciences, University of Concepcion, Casilla 160C, Concepcion, Chile
    Biochem Biophys Res Commun 397:226-31. 2010
    ..Additional experiments were performed in human neuroblastoma cells SH-SY5Y. A statistically significant decrease of cell viability was observed with Au(III) ranging from 0.1 microM to 100 microM...
  26. doi request reprint Mn2+ exerts stronger structural effects than the Mn-citrate complex on the human erythrocyte membrane and molecular models
    M Suwalsky
    Faculty of Chemical Sciences, University of Concepcion, PO Box 160 C, Concepcion, Chile
    J Inorg Biochem 104:55-61. 2010
    ..In all these systems it was found that Mn(2+) exerted considerable higher structural perturbations than the Mn-citrate complex...
  27. doi request reprint Structural effects of Zn(2+) on cell membranes and molecular models
    M Suwalsky
    University of Concepcion, Chile
    J Inorg Biochem 103:797-804. 2009
    ..This study presents evidence that 0.1mM Zn and higher concentrations affect cell membrane and molecular models...
  28. doi request reprint Human erythrocytes and molecular models of cell membranes are affected in vitro by Balbisia peduncularis (Amancay) extracts
    Mario Suwalsky
    Faculty of Chemical Sciences, University of Concepcion, Casilla 160 C, Concepcion, Chile
    Chem Biol Interact 179:413-8. 2009
    ..As a consequence, perturbations of the phospholipid bilayer packing arrangement were produced...
  29. ncbi request reprint The antiepileptic drug diphenylhydantoin affects the structure of the human erythrocyte membrane
    Mario Suwalsky
    Faculty of Chemical Sciences, University of Concepcion, Concepcion, Chile
    Z Naturforsch C 59:427-31. 2004
    ..However, the effects of the drug were observed at concentrations higher than those currently found in plasma when phenytoin is therapeutically administered...
  30. doi request reprint Human erythrocytes are affected in vitro by flavonoids of Aristotelia chilensis (Maqui) leaves
    Mario Suwalsky
    Faculty of Chemical Sciences, University of Concepcion, Concepcion, Chile
    Int J Pharm 363:85-90. 2008
    ..chilensis induced an alteration of human erythrocyte morphology from the normal discoid shape to an echinocytic form, changes that are explained in terms of the extract interaction with the membrane's outer phospholipid monolayer...
  31. doi request reprint Human cells and cell membrane molecular models are affected in vitro by chlorpromazine
    Mario Suwalsky
    Faculty of Chemical Sciences, University of Concepcion, Concepcion, Chile
    Biophys Chem 135:7-13. 2008
    ..In fact, the assays showed that CPZ induced a significant reduction of their generalized polarization (GP) and anisotropy (r) values, indicative of enhanced disorder at the polar head and acyl chain regions of the DMPC lipid bilayer...
  32. ncbi request reprint Iron affects the structure of cell membrane molecular models
    M Suwalsky
    Department of Polymers, Faculty of Chemical Sciences, University of Concepcion, Casilla 160 C, Concepcion, Chile
    Chem Phys Lipids 134:69-77. 2005
    ..These findings are consistent with the observation that iron ions change cell membrane fluidity and, therefore, affect its functions...
  33. ncbi request reprint Structural effects of titanium citrate on the human erythrocyte membrane
    M Suwalsky
    Department of Polymers, Faculty of Chemical Sciences, University of Concepcion, E Larenas 129, Casilla 160 C, Concepcion, Chile
    J Inorg Biochem 99:764-70. 2005
    ..All these findings indicate that the structural perturbations induced by titanium to human erythrocytes can be extended to other cells, thereby affecting their functions...
  34. ncbi request reprint Comparative X-ray studies on the interaction of carotenoids with a model phosphatidylcholine membrane
    Mario Suwalsky
    Faculty of Chemical Sciences, University of Concepcion, Casilla Chile
    Z Naturforsch C 57:129-34. 2002
    ..They were interpreted in terms of the molecular characteristics of DPPC and the carotenoids. Lycopene and violaxanthin induced the highest structural damage to the acyl chain and polar headgroup regions of DPPC bilayers, respectively...
  35. ncbi request reprint Toxic effects of the fungicide benomyl on cell membranes
    M Suwalsky
    Faculty of Chemical Sciences, University of Concepcion, Casilla 160 C, Concepcion, Chile
    Comp Biochem Physiol C Toxicol Pharmacol 125:111-9. 2000
    ....
  36. ncbi request reprint Dibucaine-induced modification of sodium transport in toad skin and of model membrane structures
    M Suwalsky
    Faculty of Chemical Sciences, University of Concepcion, Chile
    Z Naturforsch C 56:614-22. 2001
    ..Although it is still premature to define the molecular mechanism of action of dibucaine, the experimental results confirm the important role played by the phospholipid bilayers in the association of the anesthetic with cell membranes...
  37. ncbi request reprint Effects of AlCl3 on toad skin, human erythrocytes, and model cell membranes
    M Suwalsky
    Faculty of Chemical Sciences, University of Concepcion, Concepcion, Chile
    Brain Res Bull 55:205-10. 2001
    ....
  38. ncbi request reprint HgCl2 disrupts the structure of the human erythrocyte membrane and model phospholipid bilayers
    M Suwalsky
    Faculty of Chemical Sciences, University of Concepcion, Chile
    J Inorg Biochem 81:267-73. 2000
    ..All these findings point to the important role of the phospholipid bilayers in the interaction of Hg(II) on cell membranes...
  39. ncbi request reprint The anticancer drug cisplatin interacts with the human erythrocyte membrane
    M Suwalsky
    Faculty of Chemical Sciences, University of Concepcion, Chile
    Z Naturforsch C 55:461-6. 2000
    ..According to the bilayer couple hypothesis, this means that the drug is inserted into the inner monolayer of the erythrocyte membrane, a conclusion supported by the studies on model systems...
  40. ncbi request reprint The anticancer drug chlorambucil interacts with the human erythrocyte membrane and model phospholipid bilayers
    M Suwalsky
    Faculty of Chemical Sciences, University of Concepcion, Chile
    Z Naturforsch C 54:1089-95. 1999
    ..It is concluded that the cytotoxic effect of chlorambucil might be due to alteration of the structure and therefore of the physiological properties of cell membranes such as fluidity, permeability, receptor and channel functions...
  41. ncbi request reprint Interactions of Al(acac)3 with cell membranes and model phospholipid bilayers
    M Suwalsky
    Faculty of Chemical Sciences, University of Concepcion, Chile
    J Inorg Biochem 75:263-8. 1999
    ..It is concluded that Al(acac)3 both alters the molecular structure of the lipid bilayer, thereby modifying the biophysical properties of the cell membrane, and changes its physiological properties...
  42. ncbi request reprint The anticancer drug adriamycin interacts with the human erythrocyte membrane
    M Suwalsky
    Faculty of Chemical Sciences, University of Concepcion, Chile
    Z Naturforsch C 54:271-7. 1999
    ..It is concluded that adriamycin incorporates into both erythrocyte leaflets affecting its membrane structure...
  43. ncbi request reprint The organochlorine herbicide chloridazon interacts with cell membranes
    M Suwalsky
    Faculty of Chemical Sciences, University of Concepcion, Chile
    Comp Biochem Physiol C Pharmacol Toxicol Endocrinol 120:29-35. 1998
    ..These results are in accordance with a perturbing effect of chloridazon on the phospholipid moiety of the nerve fibre membrane leading to interference with total ion transport across the nerve skin junction...
  44. ncbi request reprint Cu2+ ions interact with cell membranes
    M Suwalsky
    Faculty of Chemical Sciences, University of Concepcion, Chile
    J Inorg Biochem 70:233-8. 1998
    ..These results lead to the conclusion that Cu2+ ions inhibited Na+ transport across the epithelial cell membranes...
  45. ncbi request reprint The local anesthetic proparacaine modifies sodium transport in toad skin and perturbs the structures of model and cell membranes
    Mario Suwalsky
    Faculty of Chemical Sciences, University of Concepcion, Chile
    Z Naturforsch C 57:930-8. 2002
    ..Thus, the LA may alter epitheial sodium channels through interaction with the lipid matrix and with channel protein residues...
  46. ncbi request reprint Structural effects of the local anesthetic bupivacaine hydrochloride on the human erythrocyte membrane and molecular models
    Mario Suwalsky
    Faculty of Chemical Sciences, University of Concepcion, Casilla 160 C, Concepcion, Chile
    Blood Cells Mol Dis 29:14-23. 2002
    ....
  47. ncbi request reprint Evidence for the hydration effect at the semiconductor phospholipid-bilayer interface by TiO2 photocatalysis
    M Suwalsky
    Faculty of Chemical Sciences, University of Concepcion, Casilla 160 C, Concepcion, Chile
    J Photochem Photobiol B 78:253-8. 2005
    ..Evidence is provided that the fluidity of the phospholipid bilayers plays a significant role when interacting in the dark with the TiO2 or in processes mediated by TiO2 under light irradiation...
  48. ncbi request reprint Effects of Pb2+ ions on Na+ transport in the isolated skin of the toad Pleurodema thaul
    Mario Suwalsky
    Faculty of Chemical Sciences, University of Concepcion, Concepcion, Chile
    Biometals 17:655-68. 2004
    ....
  49. ncbi request reprint Cadmium-induced changes in the membrane of human erythrocytes and molecular models
    M Suwalsky
    Department of Polymers, Faculty of Chemical Sciences, University of Concepcion, E Larenas 129, Casilla 160 C, Concepcion, Chile
    J Inorg Biochem 98:1061-6. 2004
    ..This conclusion is supported by fluorescence spectroscopy measurements on DMPC large unilamellar vesicles (LUV). All these findings point to the important role of phospholipid bilayers in the interaction of cadmium on cell membranes...
  50. ncbi request reprint Aluminum fluoride affects the structure and functions of cell membranes
    M Suwalsky
    Faculty of Chemical Sciences, University of Concepcion, Casilla 160 C, Concepcion, Chile
    Food Chem Toxicol 42:925-33. 2004
    ..This result was confirmed by fluorescence spectroscopy on DMPC LUV. The biphasic (stimulatory followed by inhibitory) effects on the isolated skin suggested changes in apical Cl(-) secretion and moderate ATPase inactivation...
  51. ncbi request reprint Sodium arsenite affects Na+ transport in the isolated skin of the toad Pleurodema thaul
    Mario Suwalsky
    Faculty of Chemical Sciences, University of Concepcion, Casilla 160 C, Concepcion, Chile
    Comp Biochem Physiol C Toxicol Pharmacol 146:138-46. 2007
    ....
  52. ncbi request reprint The anticancer drug cytarabine does not interact with the human erythrocyte membrane
    Mario Suwalsky
    Faculty of Chemical Sciences, University of Concepcion, Casilla 160 C, Concepcion, Chile
    Z Naturforsch C 58:885-90. 2003
    ..Therefore, it can be unambiguously concluded that this widely used anticancer drug does not interact at all with erythrocyte membranes...
  53. ncbi request reprint Effects of lead on the human erythrocyte membrane and molecular models
    M Suwalsky
    Department of Polymers, Faculty of Chemical Sciences, University of Concepcion, E Larenas 129, Concepcion, Chile
    J Inorg Biochem 97:308-13. 2003
    ....
  54. ncbi request reprint The toxicity of exposure to the organochlorine, dieldrin, at a sympathetic junction and on the skin of the frog, Caudiverbera caudiverbera
    M Suwalsky
    Faculty of Chemical Sciences, University of Concepcion, Casilla 160 C, Concepcion, Chile
    Hum Exp Toxicol 21:587-91. 2002
    ....
  55. ncbi request reprint Interaction of 2,4-dichlorophenoxyacetic acid (2,4-D) with cell and model membranes
    M Suwalsky
    Faculty of Chemical Sciences, University of Concepcion, Chile
    Biochim Biophys Acta 1285:267-76. 1996
    ..It was observed that 2,4-D induced a pronounced shape change to the erythrocytes. This effect is explained by the herbicide interaction with the outer monolayer of the red cell membrane...
  56. ncbi request reprint Interaction of the organochlorine pesticide dieldrin with phospholipid bilayers
    M Suwalsky
    Faculty of Chemical Sciences, , Chile
    Z Naturforsch C 52:450-8. 1997
    ..It was observed that dieldrin particularly interacted with DMPC liposomes and multilayers perturbing its molecular arrangements. However, no effect was noticed on erythrocytes, which might be due to its high cholesterol content...
  57. ncbi request reprint Molecular interactions of quinidine with phospholipid bilayers
    M Suwalsky
    Faculty of Chemical Sciences, , Chile
    Z Naturforsch C 50:527-34. 1995
    ..Finally, human erythrocytes which were incubated with QUIN solutions were observed by scanning electron microscopy. The results of these experiments proved that QUIN indeed interacted with phospholipid bilayers...
  58. ncbi request reprint The organochlorine pesticide heptachlor disrupts the structure of model and cell membranes
    M Suwalsky
    Faculty of Chemical Sciences, University of Concepcion, Chile
    Biochim Biophys Acta 1326:115-23. 1997
    ..It is therefore concluded that toxic effects of this pesticide can be related to its capacity to perturb the phospholipid bilayer structure, whose integrity is essential for cell membrane functions...
  59. ncbi request reprint Interaction of penicillin G with the human erythrocyte membrane and models
    M Suwalsky
    Faculty of Chemical Sciences, , Chile
    Z Naturforsch C 51:243-8. 1996
    ..This is in agreement with its reported lack of major toxicity and hematological reactions...
  60. ncbi request reprint Arsenite interactions with phospholipid bilayers as molecular models for the human erythrocyte membrane
    Mario Suwalsky
    Faculty of Chemical Sciences, University of Concepcion, Concepcion, Chile msuwalskudec cl
    Biophys Chem 127:28-35. 2007
    ..The experiments carried out by X-ray diffraction and calorimetry clearly indicated that NaAsO(2) interacted with DMPE and modified its thermotropic behaviour. No such information has been so far reported in the literature...
  61. ncbi request reprint Interaction of the antiarrhythmic drug procainamide with phospholipid bilayers
    M Suwalsky
    Faculty of Chemical Sciences, , Chile
    Z Naturforsch C 50:248-56. 1995
    ..It was found that PROC exerted very little effect upon DMPC and DMPE even at such a high concentration as 10 mM. However, at therapeutical plasma concentrations, PROC induced shape changes in vitro to red cells...
  62. ncbi request reprint X-ray studies on phospholipid bilayers. XIV. Interactions with the antiarrhythmic asocainol
    M Suwalsky
    Faculty of Chemical Sciences, , Chile
    Z Naturforsch C 48:930-8. 1993
    ..The perturbing effect of ASOC upon the bilayer structures was determined by X-ray diffraction. It was found that ASOC was able to fluidize DMPC in both media but not to DMPE...
  63. doi request reprint Interaction between Alzheimer's amyloid-beta and amyloid-beta-metal complexes with cell membranes
    Mario Suwalsky
    Faculty of Chemical Sciences, University of Concepcion, Concepcion, Chile
    J Alzheimers Dis 17:81-90. 2009
    ..Our findings imply that Al, compared to the other Abeta-metal complexes tested, could have a specifically relevant effect in enhancing Abeta toxicity...
  64. ncbi request reprint Effects of the local anesthetic benzocaine on the human erythrocyte membrane and molecular models
    Mario Suwalsky
    Faculty of Chemical Sciences, University of Concepcion, Casilla 160 C, Concepcion, Chile
    Biophys Chem 109:189-99. 2004
    ..Electrophysiological measurements indicated a significant decrease in the potential difference (PD) and in the short-circuit current (Isc) after the application of benzocaine, reflecting inhibition of active ion transport...
  65. ncbi request reprint Effects of chronic treatment with sodium tetrachloroaurate(III) in mice and membrane models
    Mario Suwalsky
    Faculty of Chemical Sciences, University of Concepcion, Chile
    J Inorg Biochem 98:2080-6. 2004
    ..These results show that toxic effects on animal brain upon treatment with sodium tetrachloroaurate develop with difficulty and may be observed only at high doses...
  66. ncbi request reprint X-ray studies on phospholipid bilayers. XIII. Interactions with gentamicin
    M Suwalsky
    Faculty of Chemical Sciences, , Chile
    Z Naturforsch C 48:632-9. 1993
    ..The maximum effect was attained when GENT interacted with DMPC in the hydrophobic medium. On the other hand, GENT in aqueous solutions was unable to perturb in any significant extent the structure of the phospholipids under study...
  67. doi request reprint In vitro protective effects of resveratrol against oxidative damage in human erythrocytes
    M Suwalsky
    Faculty of Chemical Sciences, University of Concepcion, Chile
    Biochim Biophys Acta 1848:76-82. 2015
    ..On the other hand, SEM and DM observations as well as hemolysis assays demonstrated the protective effect of RV against the deleterious effects of HClO upon human erythrocytes. ..