Thashi Chang

Summary

Publications

  1. pmc Stiff person syndrome in South Asia
    Thashi Chang
    Department of Clinical Medicine, Faculty of Medicine, University of Colombo, 25, Kynsey Road, Colombo, 00800, Sri Lanka
    BMC Res Notes 9:468. 2016
  2. pmc A rare c.183_187dupCTCAC mutation of the acetylcholine receptor CHRNE gene in a South Asian female with congenital myasthenic syndrome: a case report
    Thashi Chang
    Department of Clinical Medicine, Faculty of Medicine, University of Colombo, 25, Kynsey Road, Colombo 08, Sri Lanka
    BMC Neurol 16:195. 2016
  3. doi request reprint Prevalence of Stroke and Its Risk Factors in Urban Sri Lanka: Population-Based Study
    Thashi Chang
    From the Department of Clinical Medicine T C, S G, Department of Community Medicine C A, and Faculty of Medicine T C, S G, C A, University of Colombo, Colombo, Sri Lanka
    Stroke 46:2965-8. 2015
  4. pmc Gaze palsy, hypogeusia and a probable association with miscarriage of pregnancy--the expanding clinical spectrum of non-opticospinal neuromyelitis optica spectrum disorders: a case report
    Thashi Chang
    Department of Clinical Medicine, Faculty of Medicine, University of Colombo, 25, Kynsey Road, Colombo, 08, Sri Lanka
    BMC Res Notes 8:36. 2015
  5. pmc Spontaneous intracranial hypotension presenting as thunderclap headache: a case report
    Thashi Chang
    Department of Clinical Medicine, Faculty of Medicine, University of Colombo, 25, Kynsey Road, Colombo 08, Sri Lanka
    BMC Res Notes 8:108. 2015
  6. pmc Cyclophosphamide-induced posterior reversible encephalopathy syndrome (PRES): a case report
    Jayamalee L Jayaweera
    University Medical Unit, National Hospital, Colombo, Sri Lanka
    J Med Case Rep 8:442. 2014
  7. doi request reprint Gaze palsy, hypogeusia and a probable association with miscarriage of pregnancy - the expanding clinical spectrum of non-opticospinal neuromyelitis optica spectrum disorders: a case report
    Thashi Chang
    Department of Clinical Medicine, Faculty of Medicine, University of Colombo, 25, Kynsey Road, Colombo, 08, Sri Lanka
    BMC Res Notes 8:991. 2015
  8. doi request reprint Clinical and serological study of myasthenia gravis using both radioimmunoprecipitation and cell-based assays in a South Asian population
    Thashi Chang
    Department of Clinical Medicine, University of Colombo, Sri Lanka Electronic address
    J Neurol Sci 343:82-7. 2014
  9. pmc Cerebral infarction 3 weeks after intravenous immunoglobulin for Miller Fisher syndrome: a case report
    Thashi Chang
    Department of Clinical Medicine, Faculty of Medicine, University of Colombo, 25, Kynsey Road, Colombo, Sri Lanka
    J Med Case Rep 8:100. 2014
  10. pmc Acute ischemic stroke following Hump-nosed viper envenoming; first authenticated case
    Vijayabala Jeevagan
    University Medical Unit, National Hospital of Sri Lanka, Colombo, Sri Lanka
    Thromb J 10:21. 2012

Collaborators

  • Angela Vincent
  • Carukshi Arambepola
  • Ariaranee Gnanathasan
  • Senaka Rajapakse
  • Bethan Lang
  • David Beeson
  • Gathsaurie Neelika Malavige
  • Panduka Karunanayake
  • Subashini Jayawardana
  • Praveen Weeratunga
  • Janarthani Lohitharajah
  • Milinda Withana
  • Jayamalee L Jayaweera
  • Saroj Jayasinghe
  • Mitrakrishnan Chrishan Shivanthan
  • Laksiri Gomes
  • Sachie Fernando
  • Graham S Ogg
  • S D Jayaratne
  • Vijayabala Jeevagan
  • Gowri Rathnayake
  • Ahalya Sivashangar
  • Anthony Jin Shun Chua
  • Mah Lee Ng
  • Chathurika D Beligaswatta
  • Milinda R Withana
  • Chamila K P Dalpatadu
  • Thamara Rajapakse
  • Chaturaka Rodrigo
  • Lukmall Alles
  • Yamini De Silva
  • Nilwala Jayasinghe
  • Dinushka Jayaweerabandara
  • Maryam Salimi
  • Sujatha Ruwanpathirana
  • Sd Jayaratne
  • Harshani Perera
  • Kushan Dl Nanayakkara
  • Christeine Ariaranee Gnanathasan
  • Tharindu Wijesinghe
  • Vajini Atukorale

Detail Information

Publications21

  1. pmc Stiff person syndrome in South Asia
    Thashi Chang
    Department of Clinical Medicine, Faculty of Medicine, University of Colombo, 25, Kynsey Road, Colombo, 00800, Sri Lanka
    BMC Res Notes 9:468. 2016
    ..Stiff person syndrome is rare, but is believed to be under diagnosed with only 14 cases been reported among a 1.7 billion population in South Asia. We report the first authenticated case from Sri Lanka...
  2. pmc A rare c.183_187dupCTCAC mutation of the acetylcholine receptor CHRNE gene in a South Asian female with congenital myasthenic syndrome: a case report
    Thashi Chang
    Department of Clinical Medicine, Faculty of Medicine, University of Colombo, 25, Kynsey Road, Colombo 08, Sri Lanka
    BMC Neurol 16:195. 2016
    ..Acetylcholine receptor epsilon (ε) subunit (CHRNE) gene mutations account for about 30-50 % of genetically diagnosed cases. We report a rare CHRNE gene mutation in a South Asian female with CMS...
  3. doi request reprint Prevalence of Stroke and Its Risk Factors in Urban Sri Lanka: Population-Based Study
    Thashi Chang
    From the Department of Clinical Medicine T C, S G, Department of Community Medicine C A, and Faculty of Medicine T C, S G, C A, University of Colombo, Colombo, Sri Lanka
    Stroke 46:2965-8. 2015
    ..Stroke is a leading cause of disability and death worldwide. In the absence of published population-based prevalence data, we investigated the prevalence and risk factors of stroke in a population of varying urbanization in Sri Lanka...
  4. pmc Gaze palsy, hypogeusia and a probable association with miscarriage of pregnancy--the expanding clinical spectrum of non-opticospinal neuromyelitis optica spectrum disorders: a case report
    Thashi Chang
    Department of Clinical Medicine, Faculty of Medicine, University of Colombo, 25, Kynsey Road, Colombo, 08, Sri Lanka
    BMC Res Notes 8:36. 2015
    ..This is the first report of horizontal gaze palsy as a presenting symptom of neuromyelitis optica spectrum disorders...
  5. pmc Spontaneous intracranial hypotension presenting as thunderclap headache: a case report
    Thashi Chang
    Department of Clinical Medicine, Faculty of Medicine, University of Colombo, 25, Kynsey Road, Colombo 08, Sri Lanka
    BMC Res Notes 8:108. 2015
    ..Spontaneous intracranial hypotension presenting as thunderclap headache is recognized but rare...
  6. pmc Cyclophosphamide-induced posterior reversible encephalopathy syndrome (PRES): a case report
    Jayamalee L Jayaweera
    University Medical Unit, National Hospital, Colombo, Sri Lanka
    J Med Case Rep 8:442. 2014
    ..Reports of cyclophosphamide-induced posterior reversible encephalopathy syndrome are rare and occurred in a background of renal failure, fluid overload or active connective tissue disease...
  7. doi request reprint Gaze palsy, hypogeusia and a probable association with miscarriage of pregnancy - the expanding clinical spectrum of non-opticospinal neuromyelitis optica spectrum disorders: a case report
    Thashi Chang
    Department of Clinical Medicine, Faculty of Medicine, University of Colombo, 25, Kynsey Road, Colombo, 08, Sri Lanka
    BMC Res Notes 8:991. 2015
    ..This is the first report of horizontal gaze palsy as a presenting symptom of neuromyelitis optica spectrum disorders...
  8. doi request reprint Clinical and serological study of myasthenia gravis using both radioimmunoprecipitation and cell-based assays in a South Asian population
    Thashi Chang
    Department of Clinical Medicine, University of Colombo, Sri Lanka Electronic address
    J Neurol Sci 343:82-7. 2014
    ..We studied the seroprevalence of AChR and MuSK antibodies using both radioimmunoprecipitation (RIA) and CBA amongst MG patients in Sri Lanka and related their antibody status to their clinical subtypes and severity...
  9. pmc Cerebral infarction 3 weeks after intravenous immunoglobulin for Miller Fisher syndrome: a case report
    Thashi Chang
    Department of Clinical Medicine, Faculty of Medicine, University of Colombo, 25, Kynsey Road, Colombo, Sri Lanka
    J Med Case Rep 8:100. 2014
    ..This is the first report of cerebral infarction occurring after a longer latency of 3 weeks following intravenous immunoglobulin therapy in a patient presenting with Miller Fisher syndrome...
  10. pmc Acute ischemic stroke following Hump-nosed viper envenoming; first authenticated case
    Vijayabala Jeevagan
    University Medical Unit, National Hospital of Sri Lanka, Colombo, Sri Lanka
    Thromb J 10:21. 2012
    ..This case describes an authenticated first case of ischemic stroke in a 65 year old male following envenoming by H.hypnale in Sri Lanka...
  11. pmc Hydrogen sulphide inhalational toxicity at a petroleum refinery in Sri Lanka: a case series of seven survivors following an industrial accident and a brief review of medical literature
    Mitrakrishnan Chrishan Shivanthan
    National Hospital of Sri Lanka, Colombo, Sri Lanka
    J Occup Med Toxicol 8:9. 2013
    ..A brief literature review explores the manifestations, pathophysiology and available modalities of treatment of hydrogen sulphide inhalation toxicity...
  12. pmc Multiple ring-enhancing cerebral lesions in systemic lupus erythematosis: a case report
    Thashi Chang
    Department of Clinical Medicine, Faculty of Medicine, University of Colombo, Colombo, Sri Lanka
    J Med Case Rep 6:172. 2012
    ..It is also a race against time to diagnose, as many of these infections can be fatal without timely intervention...
  13. pmc Evaluation of the WHO revised criteria for classification of clinical disease severity in acute adult dengue infection
    S D Jayaratne
    Department of Medicine, University of Sri Jayawardanapura, Nugegoda, Sri Lanka
    BMC Res Notes 5:645. 2012
    ..We proceeded to determine the usefulness of the warning signs in the new WHO guidelines in predicting SD and we have also attempted to define other simple laboratory parameters that could be useful in predicting SD...
  14. pmc Serum IL-10 as a marker of severe dengue infection
    Gathsaurie Neelika Malavige
    Department of Microbiology, University of Sri Jayawardanapura, Nugegoda, Sri Lanka
    BMC Infect Dis 13:341. 2013
    ..We proceeded to determine if these cytokines could be used as biomarkers in a large cohort of adult dengue patients with varying severity of dengue infection...
  15. doi request reprint Hashimoto encephalopathy: clinical and MRI improvement following high-dose corticosteroid therapy
    Thashi Chang
    Institute of Neurology, National Hospital of Sri Lanka, Colombo, Sri Lanka
    Neurologist 16:394-6. 2010
    ..Diffuse or focal white matter changes suggesting primary demyelination on magnetic resonance imaging (MRI) has been reported in only a few patients with HE. Follow-up imaging studies have been sparse...
  16. doi request reprint MuSK-antibody-positive myasthenia gravis in a South Asian population
    Thashi Chang
    Department of Clinical Medicine, University of Colombo, Sri Lanka
    J Neurol Sci 284:33-5. 2009
    ..The presence of anti-MuSK antibodies defines a distinct clinico-immuno-pathological subtype of MG. We analysed for the first time the serology and clinical characteristics of MuSK-MG in a South Asian population...
  17. pmc Dengue fever presenting with acute cerebellitis: a case report
    Milinda Withana
    Department of Clinical Medicine, Faculty of Medicine, University of Colombo, Colombo, Sri Lanka
    BMC Res Notes 7:125. 2014
    ..With the increasing numbers, rare manifestations of dengue are occasionally encountered. We report a patient who presented with bilateral cerebellar signs as the presenting feature of dengue...
  18. pmc Plasmodium falciparum and Mycoplasma pneumoniae co-infection presenting with cerebral malaria manifesting orofacial dyskinesia and haemophagocytic lymphohistiocytosis
    Praveen Weeratunga
    University Medical Unit, National Hospital of Sri Lanka, Colombo, Sri Lanka
    Malar J 15:461. 2016
    ..This is the first report of Plasmodium falciparum and Mycoplasma pneumoniae co-infection in a human host presenting with cerebral malaria manifesting orofacial dyskinesias and haemophagocytic lymphohistiocytosis...
  19. pmc Chronic Musculoskeletal Disabilities following Snake Envenoming in Sri Lanka: A Population-Based Study
    Subashini Jayawardana
    Department of Allied Health Sciences, University of Colombo, Colombo, Sri Lanka
    PLoS Negl Trop Dis 10:e0005103. 2016
    ..We conducted a population-based, cross-sectional study in an agricultural community to describe the chronic musculoskeletal disabilities of snake envenoming...
  20. pmc Emergence of human West Nile Virus infection in Sri Lanka
    Janarthani Lohitharajah
    Faculty of Medicine, University of Colombo, Colombo, Sri Lanka
    BMC Infect Dis 15:305. 2015
    ..Although outbreaks have been reported in Asia, human WNV infection has not been previously reported in Sri Lanka...
  21. pmc Immunization against GAD induces antibody binding to GAD-independent antigens and brainstem GABAergic neuronal loss
    Thashi Chang
    Neuroimmunology Group, Weatherall Institute of Molecular Medicine and Nuffield Department of Clinical Neurosciences, John Radcliffe Hospital, University of Oxford, Oxford, United Kingdom Department of Clinical Medicine, University of Colombo, Colombo, Sri Lanka
    PLoS ONE 8:e72921. 2013
    ....