Affiliation: York University
- Modelling population growth with delayed nonlocal reaction in 2-dimensionsDong Liang
Department of Mathematics and Statistics, York University, Toronto, Ontario, Canada M3J 1P3
Math Biosci Eng 2:111-32. 2005..We also investigate numerically the efects of various parameters on the period, the peak and the shape of the periodic wave as well as the shape of the asymptotically stable steady state solution...
- Projective clustering using neural networks with adaptive delay and signal transmission lossJianhong Wu
MITACS Centre for Disease Modeling, and Department of Mathematics and Statistics, York University, Toronto, Ontario M3J1P3, Canada
Neural Comput 23:1568-604. 2011..We give a complete description of the computational performance of the network for a wide range of parameter values...
- Carlos is a CanadianJianhong Wu
Centre for Disease Modeling, York University, 4700 Keele Street, Toronto, ON M3J1P3, Canada
Math Biosci Eng 10:1687-9. 2013..We prove that Carlos is a Canadian, and document some important contribution of Carlos to the growth of mathematical epidemiology in Canada. ..
- A sex-role-preference model for HIV transmission among men who have sex with men in ChinaJie Lou
Department of Mathematics, Shanghai University, 99 Shangda Road Shanghai, 200444, PR China
BMC Public Health 9:S10. 2009..China has a sizable population of MSM, including gay, bisexual men, money boys and some rural workers. So reducing HIV infection in this population is an important component of the national HIV/AIDS prevention and control program...
- Modelling the evolution of drug resistance in the presence of antiviral drugsJianhong Wu
Center for Disease Modeling, Department of Mathematics and Statistics, York University, 4700 Keele Street, Toronto, M3J 1P3, Canada
BMC Public Health 7:300. 2007..Mathematical modelling may help guide the design of treatment programs and also may help us better understand the potential benefits and limitations of prevention strategies...
- The role of cellular immunity in influenza H1N1 population dynamicsVenkata R Duvvuri
Centre for Disease Modelling, York University, Toronto, Ontario
BMC Infect Dis 12:329. 2012..Whether, and to what extent, the effect of this self-protective mechanism can be captured in the population dynamics of an influenza epidemic has not been addressed...
- The human immune system recognizes neopeptides derived from mitochondrial DNA deletionsBhargavi Duvvuri
School of Kinesiology and Health Science, York University, Toronto, Ontario M3J 1P3, Canada
J Immunol 192:4581-91. 2014..These findings provide proof of principal that the immune system can recognize peptides arising from spontaneous somatic mutations and that such responses might be primed by foreign peptides and/or be cross-reactive with self. ..
- Preexisting CD4+ T-cell immunity in human population to avian influenza H7N9 virus: whole proteome-wide immunoinformatics analysesVenkata R Duvvuri
Centre for Disease Modelling, York Institute of Health Research, Toronto, Canada
PLoS ONE 9:e91273. 2014..This information is crucial for public health policy, in targeting priority groups for immunization programs...
- T cell memory to evolutionarily conserved and shared hemagglutinin epitopes of H1N1 viruses: a pilot scale studyVenkata R Duvvuri
Biology Department, York University, Toronto, Canada
BMC Infect Dis 13:204. 2013..We carried out a pilot scale study by conducting in silico and in vitro T cellular assays in healthy population, to evaluate the pre-existing immunity to A (H1N1)pdm09 strain...
- Multistability in spiking neuron models of delayed recurrent inhibitory loopsJianfu Ma
Neural Comput 19:2124-48. 2007..We demonstrate how configurational information corresponding to these distinct periods can be explored to calculate and predict the number of stable patterns...
- Influence of backward bifurcation in a model of hepatitis B and C virusesRedouane Qesmi
Department of Mathematics and Statistics, York University, Toronto, Ontario, Canada
Math Biosci 224:118-25. 2010..Consequently, we investigate possible factors that are responsible for HBV/HCV infection and assess control strategies to reduce HBV/HCV reinfection and improve graft survival after liver transplantation...
- Critical delay for overshooting in planned arm movements with delayed feedbackDan Beamish
Department of Mathematics, York University, North York, Ontario, Canada M3J 1P3
J Math Biol 50:22-48. 2005..Thus neurobiological or artificial systems modelled by the VITE sensory-motor loop can tolerate an arbitrarily large delay if the movement speed is sufficiently slow...
- Role of positive selection pressure on the evolution of H5N1 hemagglutininVenkata R S K Duvvuri
Center for Disease Modeling, York Institute of Health Research, York University, Toronto, Ontario, Canada
Genomics Proteomics Bioinformatics 7:47-56. 2009..Our study reports new mutations in functional regions of HA that might provide markers for vaccine design or can be used to predict isolates of pandemic potential...
- HIV epidemic in Far-Western Nepal: effect of seasonal labor migration to IndiaNaveen K Vaidya
Center for Disease Modeling, Department of Mathematics and Statistics, York University, Toronto, ON, Canada
BMC Public Health 11:310. 2011..The present study aims to evaluate the role of such seasonal labor-migration to India on HIV transmission in Far-Western Nepal and to assess prevention programs...
- Persistent high incidence of tuberculosis among immigrants in a low-incidence country: impact of immigrants with early or late latencyHongbin Guo
Centre for Disease Modeling, Department of Mathematics and Statistics, York University, 4700 Keele Street Toronto, ON, M3J 1P3, Canada
Math Biosci Eng 8:695-709. 2011..The global dynamics of the system is completely classified, numerical simulations are carried out for different scenarios, and potential applications to public health policy are discussed...
- The utility of preemptive mass influenza vaccination in controlling a sars outbreak during flu seasonQingling Zeng
Department of Mathematics and Statistics, York University, 4700 Keele Street, Toronto, ON M3J 1P3, Canada
Math Biosci Eng 4:739-54. 2007....
- The impact of prophylaxis of healthcare workers on influenza pandemic burdenMichael Gardam
Toronto General Hospital, Eaton South Wing, Toronto, Ontario M5G 2C4, Canada
J R Soc Interface 4:727-34. 2007..Therefore, prophylaxis of HCWs should be considered an important part of public health efforts for minimizing influenza pandemic burden and its socio-economic disruption...
- The impact of maturation delay of mosquitoes on the transmission of West Nile virusGuihong Fan
Centre for Disease Modeling, Laboratory of Mathematical Parallel Systems, Department of Mathematics and Statistics, York University, Toronto, ON, Canada M3J 1P3
Math Biosci 228:119-26. 2010..Numerical results of the model show that a combination of the maturation time and the vertical transmission of the virus in mosquitoes has substantial influence on the abundance and number of infection peaks of the infectious mosquitoes...
- How to measure the impacts of antibiotic resistance and antibiotic development on empiric therapy: new composite indicesJosie S Hughes
Centre for Disease Modelling, York University, Toronto, Ontario, Canada
BMJ Open 6:e012040. 2016..Summary measures are needed to communicate the importance of resistance, plan and evaluate interventions, and direct policy and investment...
- Influenza H3N2 variant viruses with pandemic potential: preventing catastrophe in remote and isolated Canadian communitiesMarek Laskowski
Agent Based Modelling Laboratory, York University, Toronto, Ontario, Canada
Prev Med 57:910-3. 2013..To evaluate the impact of age-specific cross-reactive antibody protection levels on the outcomes of a pandemic outbreak of new variants of H3N2 influenza A viruses (H3N2v)...
- Enhanced surveillance on food-borne disease outbreaks: dynamics of cross-contamination in biocidal wash procedureDaniel Munther
Centre for Disease Modelling, Department of Mathematics and Statistics, York University, Toronto, Canada
J Theor Biol 321:28-35. 2013..In addition to showing how these parameters affect contamination levels, we recommend that in order to prevent potential source misidentification, at least 2.2 mg/L of free chlorine should be used during a wash lasting at least 30s...
- Developing a temperature-driven map of the basic reproductive number of the emerging tick vector of Lyme disease Ixodes scapularis in CanadaXiaotian Wu
Centre for Disease Modelling, York Institute of Health Research, Toronto, Ontario, Canada
J Theor Biol 319:50-61. 2013....
- Modeling spruce budworm population revisited: impact of physiological structure on outbreak controlNaveen K Vaidya
Department of Mathematics and Statistics, York University, Toronto, M3J 1P3, Canada
Bull Math Biol 70:769-84. 2008....
- Stabilised DNA secondary structures with increasing transcription localise hypermutable bases for somatic hypermutation in IGHV3-23Bhargavi Duvvuri
School of Kinesiology and Health Science, Faculty of Health, York University, 4700 Keele Street, Toronto, ON M3J 1P3, Canada
Immunogenetics 64:481-96. 2012....
- Linking antimicrobial prescribing to antimicrobial resistance in the ICU: before and after an antimicrobial stewardship programAmy Hurford
The Fields Institute for Research in Mathematical Sciences, Toronto, ON, Canada
Epidemics 4:203-10. 2012....
- Richards model revisited: validation by and application to infection dynamicsXiang Sheng Wang
Mprime Centre for Disease Modelling, York Institute for Health Research, York University, Toronto, Canada
J Theor Biol 313:12-9. 2012....
- Population profiling in China by gender and age: implication for HIV incidencesYuanyi Pan
Centre for Disease Modeling, Department of Mathematics and Statistics, York University, Toronto, Ontario, Canada
BMC Public Health 9:S9. 2009..This population profiling by age and gender will assist in more precise prediction of HIV incidences...
- Epidemiological impact of a genital herpes type 2 vaccine for young femalesYijun Lou
Mathematics and Statistics, York University, Toronto, Ontario, Canada
PLoS ONE 7:e46027. 2012..This will also result in a decrease of maternal-fetal transmission of HSV-2 infection. Another important, if commonsense, conclusion is that vaccination of some females reduces infection in men, which then reduces infection in women...
- Indigenous populations health protection: a Canadian perspectiveKatya L Richardson
Centre for Disease Modelling, York Institute for Health Research, York University, Toronto, ON M3J 1P3, Canada
BMC Public Health 12:1098. 2012....
- Variability in transmissibility of the 2009 H1N1 pandemic in Canadian communitiesLuiz C Mostaço-Guidolin
Centre for Disease Modelling, York University, 4700 Keele Street, Toronto, ON, M3J 1P3, Canada
BMC Res Notes 4:537. 2011..We sought to investigate the variability in transmissibility of H1N1 pandemic in different health regions (including urban centres and remote, isolated communities) in the province of Manitoba, Canada...
- Modeling spatial spread of west nile virus and impact of directional dispersal of birdsRongsong Liu
Laboratory for Industrial and Applied Mathematics, Department of Mathematics and Statistics, York University, 4700 Keele Street, Toronto, ON, M3J 1P3, Canada
Math Biosci Eng 3:145-60. 2006....
- Highly conserved cross-reactive CD4+ T-cell HA-epitopes of seasonal and the 2009 pandemic influenza virusesVenkata R S K Duvvuri
MITACS Centre for Disease Modeling, York Institute of Health Research, Toronto, Ontario, Canada
Influenza Other Respir Viruses 4:249-58. 2010....
- When is quarantine a useful control strategy for emerging infectious diseases?Troy Day
Department of Mathematics and Statistics, Queen s University, Kingston, Ontario, Canada
Am J Epidemiol 163:479-85. 2006..When isolation is ineffective, the use of quarantine will be most beneficial when there is significant asymptomatic transmission and if the asymptomatic period is neither very long nor very short...
- Projective ART for clustering data sets in high dimensional spacesYongqiang Cao
Department of Mathematics and Statistics, York University, Toronto, Ontario, Canada
Neural Netw 15:105-20. 2002..Illustrative examples are provided, simulations on high dimensional synthetic data and comparisons with Fuzzy ART module and PROCLUS are also reported...