Affiliation: University of Alberta
- Regulation of prostaglandin endoperoxide H2 synthase in term human gestational tissuesT Zakar
Department of Obstetrics and Gynaecology, University of Alberta Perinatal Research Centre, Edmonton, Canada
Acta Physiol Hung 84:109-18. 1996..However, the role of these effectors in the in vivo control of PGHS-2 expression remains to be determined...
- Regulation of prostaglandin H2 synthase-2 expression in primary human amnion cells by tyrosine kinase dependent mechanismsT Zakar
Perinatal Research Centre, Department of Obstetrics and Gynaecology, University of Alberta, Edmonton, Alberta, Canada
Biochim Biophys Acta 1391:37-51. 1998..Tyrosine kinase inhibitors may constitute a new category of PGHS-2 inhibitors that act by blocking the expression of the enzyme...
- Tyrosine kinase inhibitors block the glucocorticoid stimulation of prostaglandin endoperoxide H synthase expression in amnion cellsT Zakar
University of Alberta Perinatal Research Centre, Department of Obstetrics and Gynaecology, Edmonton, Canada
Can J Physiol Pharmacol 77:138-42. 1999..The role of tyrosine kinase dependent mechanisms in the control of amnion cell responsiveness to corticosteroids remains to be established...
- Glucocorticoid stimulation of amnion cell prostaglandin synthesis: suppression by protein kinase C inhibitors and independence of phorbol ester-sensitive protein kinase CT Zakar
Department of Obstetrics and Gynaecology, University of Alberta, Edmonton, Canada
Biochim Biophys Acta 1136:161-8. 1992..It is suggested that the response of human amnion cells to glucocorticoids is modulated by protein kinase(s) other than phorbol ester-sensitive PKC and cyclic AMP-dependent protein kinase...