G Wells

Summary

Affiliation: University of Ottawa Heart Institute
Country: Canada

Publications

  1. doi request reprint Risedronate for the primary and secondary prevention of osteoporotic fractures in postmenopausal women
    G Wells
    University of Ottawa Heart Institute, Cardiovascular Research Reference Centre, Room H1 1, 40 Ruskin Street, Ottawa, Ontario, Canada, K1Y 4W7
    Cochrane Database Syst Rev . 2008
  2. doi request reprint Etidronate for the primary and secondary prevention of osteoporotic fractures in postmenopausal women
    G A Wells
    University of Ottawa Heart Institute, Cardiovascular Research Reference Centre, Room H1 1, 40 Ruskin Street, Ottawa, Ontario, Canada K1Y 4W7
    Cochrane Database Syst Rev . 2008
  3. doi request reprint Alendronate for the primary and secondary prevention of osteoporotic fractures in postmenopausal women
    G A Wells
    University of Ottawa Heart Institute, Cardiovascular Research Reference Centre, Room H1 1, 40 Ruskin Street, Ottawa, Ontario, Canada K1Y 4W7
    Cochrane Database Syst Rev . 2008
  4. pmc Limitations of free-form-text diagnostic requisitions as a tool for evaluating adherence to appropriate use criteria for transthoracic echocardiography
    Behnam Banihashemi
    Department of Medicine, Division of Cardiology, University of Ottawa Heart Institute, University of Ottawa, 40 Ruskin Street, Rm 3407B, K1Y 4W7 Ottawa, Ontario, Canada
    Cardiovasc Ultrasound 13:4. 2015
  5. pmc Routine versus selective cardiac magnetic resonance in non-ischemic heart failure - OUTSMART-HF: study protocol for a randomized controlled trial (IMAGE-HF (heart failure) project 1-B)
    Ian Paterson
    Mazankowski Alberta Heart Institute, University of Alberta, Edmonton, AB, Canada
    Trials 14:332. 2013
  6. pmc Computed tomographic coronary angiography for patients with heart failure (CTA-HF): a randomized controlled trial (IMAGE HF Project 1-C)
    Benjamin J W Chow
    Department of Medicine, Division of Cardiology, including Cardiac Imaging, The Heart Failure Program, and the Cardiac ResearchMethods Centre, University of Ottawa Heart Institute, 40 Ruskin Street, Ottawa, ON K1Y 4W7, Canada
    Trials 14:443. 2013
  7. pmc A Microsoft-Excel-based tool for running and critically appraising network meta-analyses--an overview and application of NetMetaXL
    Stephen Brown
    Ottawa Hospital Research Institute, Center for Practice Changing Research Building, Ottawa Hospital General Campus, PO Box 201B, Ottawa, ON K1H 8L6, Canada
    Syst Rev 3:110. 2014
  8. pmc Risk stratification of adult emergency department syncope patients to predict short-term serious outcomes after discharge (RiSEDS) study
    Venkatesh Thiruganasambandamoorthy
    Department of Emergency Medicine, University of Ottawa, Ottawa, Canada
    BMC Emerg Med 14:8. 2014
  9. pmc Chemotherapy regimens for advanced pancreatic cancer: a systematic review and network meta-analysis
    Gillian K Gresham
    Department of Epidemiology and Community Medicine, University of Ottawa, Ottawa, Ontario, Canada
    BMC Cancer 14:471. 2014
  10. pmc Alternative Imaging Modalities in Ischemic Heart Failure (AIMI-HF) IMAGE HF Project I-A: study protocol for a randomized controlled trial
    Eileen O'Meara
    Montreal Heart Institute, Montreal, QC, Canada
    Trials 14:218. 2013

Collaborators

Detail Information

Publications92

  1. doi request reprint Risedronate for the primary and secondary prevention of osteoporotic fractures in postmenopausal women
    G Wells
    University of Ottawa Heart Institute, Cardiovascular Research Reference Centre, Room H1 1, 40 Ruskin Street, Ottawa, Ontario, Canada, K1Y 4W7
    Cochrane Database Syst Rev . 2008
    ..Risedronate belongs to the bisphosphonate class of drugs which act to inhibit bone resorption by interfering with the activity of osteoclasts...
  2. doi request reprint Etidronate for the primary and secondary prevention of osteoporotic fractures in postmenopausal women
    G A Wells
    University of Ottawa Heart Institute, Cardiovascular Research Reference Centre, Room H1 1, 40 Ruskin Street, Ottawa, Ontario, Canada K1Y 4W7
    Cochrane Database Syst Rev . 2008
    ..Etidronate belongs to the bisphosphonate class of drugs which act to inhibit bone resorption by interfering with the activity of osteoclasts...
  3. doi request reprint Alendronate for the primary and secondary prevention of osteoporotic fractures in postmenopausal women
    G A Wells
    University of Ottawa Heart Institute, Cardiovascular Research Reference Centre, Room H1 1, 40 Ruskin Street, Ottawa, Ontario, Canada K1Y 4W7
    Cochrane Database Syst Rev . 2008
    ..Alendronate belongs to the bisphosphonate class of drugs, which act to inhibit bone resorption by interfering with the activity of osteoclasts...
  4. pmc Limitations of free-form-text diagnostic requisitions as a tool for evaluating adherence to appropriate use criteria for transthoracic echocardiography
    Behnam Banihashemi
    Department of Medicine, Division of Cardiology, University of Ottawa Heart Institute, University of Ottawa, 40 Ruskin Street, Rm 3407B, K1Y 4W7 Ottawa, Ontario, Canada
    Cardiovasc Ultrasound 13:4. 2015
    ..We investigated whether standard free-form-text TTE referral requisitions can be used to evaluate AUC adherence...
  5. pmc Routine versus selective cardiac magnetic resonance in non-ischemic heart failure - OUTSMART-HF: study protocol for a randomized controlled trial (IMAGE-HF (heart failure) project 1-B)
    Ian Paterson
    Mazankowski Alberta Heart Institute, University of Alberta, Edmonton, AB, Canada
    Trials 14:332. 2013
    ..This will lead to a reduction in the non-specific diagnoses of idiopathic dilated cardiomyopathy and HF with preserved ejection fraction...
  6. pmc Computed tomographic coronary angiography for patients with heart failure (CTA-HF): a randomized controlled trial (IMAGE HF Project 1-C)
    Benjamin J W Chow
    Department of Medicine, Division of Cardiology, including Cardiac Imaging, The Heart Failure Program, and the Cardiac ResearchMethods Centre, University of Ottawa Heart Institute, 40 Ruskin Street, Ottawa, ON K1Y 4W7, Canada
    Trials 14:443. 2013
    ..Acknowledging the aging population, the growing prevalence of HF and the increasing financial burden of healthcare, we need to identify non-invasive diagnostic tests that are available, safe, accurate and cost-effective...
  7. pmc A Microsoft-Excel-based tool for running and critically appraising network meta-analyses--an overview and application of NetMetaXL
    Stephen Brown
    Ottawa Hospital Research Institute, Center for Practice Changing Research Building, Ottawa Hospital General Campus, PO Box 201B, Ottawa, ON K1H 8L6, Canada
    Syst Rev 3:110. 2014
    ....
  8. pmc Risk stratification of adult emergency department syncope patients to predict short-term serious outcomes after discharge (RiSEDS) study
    Venkatesh Thiruganasambandamoorthy
    Department of Emergency Medicine, University of Ottawa, Ottawa, Canada
    BMC Emerg Med 14:8. 2014
    ..The goal of this study is to prospectively identify risk factors and to derive a clinical decision tool to accurately predict those at risk for serious outcomes after ED discharge within 30 days...
  9. pmc Chemotherapy regimens for advanced pancreatic cancer: a systematic review and network meta-analysis
    Gillian K Gresham
    Department of Epidemiology and Community Medicine, University of Ottawa, Ottawa, Ontario, Canada
    BMC Cancer 14:471. 2014
    ..We therefore conducted a systematic review and Bayesian network meta-analysis to assess the comparative safety and efficacy of chemotherapy regimens for the treatment of advanced pancreatic cancer...
  10. pmc Alternative Imaging Modalities in Ischemic Heart Failure (AIMI-HF) IMAGE HF Project I-A: study protocol for a randomized controlled trial
    Eileen O'Meara
    Montreal Heart Institute, Montreal, QC, Canada
    Trials 14:218. 2013
    ....
  11. pmc The implementation of a community-based aerobic walking program for mild to moderate knee osteoarthritis: a knowledge translation randomized controlled trial: part II: clinical outcomes
    Lucie Brosseau
    Public Health, specialization in Epidemiology, University Research Chair, School of Rehabilitation Sciences, University of Ottawa, Ottawa, Canada
    BMC Public Health 12:1073. 2012
    ..There is therefore a need to improve knowledge translation in order to influence individuals to adopt effective self-management interventions, such as an adapted walking program...
  12. pmc The implementation of a community-based aerobic walking program for mild to moderate knee osteoarthritis (OA): a knowledge translation (KT) randomized controlled trial (RCT): Part I: The Uptake of the Ottawa Panel clinical practice guidelines (CPGs)
    Lucie Brosseau
    School of Rehabilitation Sciences, University of Ottawa, Ottawa, Canada
    BMC Public Health 12:871. 2012
    ....
  13. pmc A tutorial on sensitivity analyses in clinical trials: the what, why, when and how
    Lehana Thabane
    Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, ON, Canada
    BMC Med Res Methodol 13:92. 2013
    ..The current paper is the second in a series of tutorial-type manuscripts intended to discuss and clarify aspects related to key methodological issues in the design and analysis of clinical trials...
  14. pmc Systematic reviews need to consider applicability to disadvantaged populations: inter-rater agreement for a health equity plausibility algorithm
    Vivian Welch
    Clinical Epidemiology Unit, Ottawa Hospital Research Institute, Ottawa Hospital, Ottawa, ON, Canada
    BMC Med Res Methodol 12:187. 2012
    ....
  15. pmc Quality of cardiovascular disease care in Ontario, Canada: missed opportunities for prevention - a cross sectional study
    Clare Liddy
    C T Lamont Primary Health Care Research Centre, Bruyère Research Institute, Ottawa, ON, Canada
    BMC Cardiovasc Disord 12:74. 2012
    ..We examined primary care practice adherence to recommended care guidelines associated with the prevention and management of CVD for high risk patients...
  16. pmc Canadian-led capacity-building in biostatistics and methodology in cardiovascular and diabetes trials: the CANNeCTIN Biostatistics and Methodological Innovation Working Group
    Lehana Thabane
    Department of Clinical Epidemiology and Biostatistics, McMaster University, 1200 Main Street West, Hamilton, Ontario, L8N 3Z5, Canada
    Trials 12:48. 2011
    ..The ultimate goal is to enhance global health by contributing to efforts to reduce the burden of CVD and DM...
  17. pmc Improved delivery of cardiovascular care (IDOCC) through outreach facilitation: study protocol and implementation details of a cluster randomized controlled trial in primary care
    Clare Liddy
    C T Lamont Primary Health Care Research Centre, Elisabeth Bruyere Research Institute, Ottawa, Ontario, Canada
    Implement Sci 6:110. 2011
    ....
  18. pmc Development of a self-administered early inflammatory arthritis detection tool
    Mary J Bell
    Division of Rheumatology, Department of Medicine, University of Toronto, Sunnybrook Health Sciences Centre, Toronto, Canada
    BMC Musculoskelet Disord 11:50. 2010
    ..The objective of this study was to develop a self-administered EIA detection tool for implementation in pre-primary care settings...
  19. pmc Development of AMSTAR: a measurement tool to assess the methodological quality of systematic reviews
    Beverley J Shea
    EMGO Institute, VU University Medical Center, Amsterdam, The Netherlands
    BMC Med Res Methodol 7:10. 2007
    ..Our objective was to develop an instrument to assess the methodological quality of systematic reviews, building upon previous tools, empirical evidence and expert consensus...
  20. pmc Evaluation of the safety of C-spine clearance by paramedics: design and methodology
    Christian Vaillancourt
    Ottawa Hospital Research Institute, Clinical Epidemiology Program, The Ottawa Hospital Civic Campus, 1053 Carling Avenue, Room F 658, Ottawa, ON, K1Y 4E9, Canada
    BMC Emerg Med 11:1. 2011
    ..The prolonged immobilization is often unnecessary and adds to the burden of already overtaxed emergency medical services systems and crowded emergency departments...
  21. pmc A survey of factors associated with the successful recognition of agonal breathing and cardiac arrest by 9-1-1 call takers: design and methodology
    Christian Vaillancourt
    Ottawa Hospital Research Institute, Clinical Epidemiology Program, The Ottawa Hospital Civic Campus Floor 6, Box 685, 1053 Carling Avenue, Ottawa Ontario, K1Y 4E9, Canada
    BMC Emerg Med 9:14. 2009
    ..Improving 9-1-1 call takers' ability to recognize agonal breathing as a sign of cardiac arrest could result in improved bystander cardiopulmonary resuscitation and survival rates for out-of-hospital cardiac arrest victims...
  22. pmc A study to derive a clinical decision rule for triage of emergency department patients with chest pain: design and methodology
    Erik P Hess
    Department of Emergency Medicine, University of Ottawa, Ottawa, Canada
    BMC Emerg Med 8:3. 2008
    ..Currently no methodologically robust clinical decision rule identifies patients safe for early discharge...
  23. pmc A survey of attitudes and factors associated with successful cardiopulmonary resuscitation (CPR) knowledge transfer in an older population most likely to witness cardiac arrest: design and methodology
    Christian Vaillancourt
    Ottawa Health Research Institute, Clinical Epidemiology Program, Ottawa, Canada
    BMC Emerg Med 8:13. 2008
    ..However, interest in CPR training appears to decrease with advancing age. Behaviour surrounding CPR training and performance has never been studied using well validated behavioural theories...
  24. pmc An evaluation of 9-1-1 calls to assess the effectiveness of dispatch-assisted cardiopulmonary resuscitation (CPR) instructions: design and methodology
    Christian Vaillancourt
    Ottawa Health Research Institute, Clinical Epidemiology Program, Ottawa, Canada
    BMC Emerg Med 8:12. 2008
    ..Dispatch-assisted CPR instructions are recommended by the International Guidelines on Emergency Cardiovascular Care, but their ability to improve cardiac arrest survival remains unclear...
  25. ncbi request reprint Responsiveness of patient reported outcomes including fatigue, sleep quality, activity limitation, and quality of life following treatment with abatacept for rheumatoid arthritis
    G Wells
    Department of Epidemiology and Community Medicine, University of Ottawa, 451 Smyth Rd, Ottawa, Ontario, KIH 8M5 Canada
    Ann Rheum Dis 67:260-5. 2008
    ..To evaluate the responsiveness of patient reported outcomes (PROs), including fatigue, sleep, activity limitation, and quality of life, in patients with rheumatoid arthritis (RA)...
  26. pmc Cardiac resynchronization therapy: a meta-analysis of randomized controlled trials
    George Wells
    University of Ottawa Heart Institute, Ottawa, Ont
    CMAJ 183:421-9. 2011
    ..We performed a meta-analysis including the RAFT trial to determine the effect of cardiac resynchronization therapy with or without an implantable defibrillator on mortality...
  27. pmc Validation of the 28-joint Disease Activity Score (DAS28) and European League Against Rheumatism response criteria based on C-reactive protein against disease progression in patients with rheumatoid arthritis, and comparison with the DAS28 based on erythr
    G Wells
    Department of Epidemiology and Community Medicine, University of Ottawa, Canada
    Ann Rheum Dis 68:954-60. 2009
    ..To validate and compare the definition of the Disease Activity Score 28 based on C-reactive protein (DAS28 (CRP)) to the definition based on erythrocyte sedimentation rate (ESR)...
  28. doi request reprint Investigating the validity of the minimal disease activity state for patients with rheumatoid arthritis treated with abatacept
    George A Wells
    Department of Epidemiology and Community Medicine, University of Ottawa, 451 Smyth Road, Ottawa, Ontario KIH 8M5, Canada
    J Rheumatol 36:260-5. 2009
    ..To validate the definitions of minimal disease activity (MDA) in patients with rheumatoid arthritis (RA) and to compare abatacept to control with respect to patients attaining a state of MDA...
  29. doi request reprint Patient-driven outcomes in rheumatoid arthritis
    George A Wells
    Department of Epidemiology and Community Medicine, University of Ottawa, 451 Smyth Road, Ottawa, Ontario K1H 8M5
    J Rheumatol Suppl 82:33-8. 2009
    ..It is proposed that factors such as Health Assessment Questionnaire scores, fatigue, sleep, and physical and mental function become part of a patient's core set of outcomes when assessing patients with RA...
  30. doi request reprint Assessing quality of sleep in patients with rheumatoid arthritis
    George A Wells
    Department of Epidemiology and Community Medicine, University of Ottawa, Ottawa, Ontario, Canada
    J Rheumatol 36:2077-86. 2009
    ..Sleep domains have been reviewed, and several sleep instruments have been identified. These instruments should be considered for use in planned clinical trials of RA patients to assess their applicability...
  31. doi request reprint Investigation into the impact of abatacept on sleep quality in patients with rheumatoid arthritis, and the validity of the MOS-Sleep questionnaire Sleep Disturbance Scale
    George Wells
    Department of Epidemiology and Community Medicine, University of Ottawa Heart Institute, 40 Ruskin Street, Ottawa, Ontario K1Y 4W7, Canada
    Ann Rheum Dis 69:1768-73. 2010
    ..To assess the impact of abatacept on sleep quality in patients with rheumatoid arthritis (RA), and the validity of the sleep disturbance scale of the Medical Outcomes Study Sleep Questionnaire (MOS-Sleep)...
  32. doi request reprint Validity of quality of life measurement tools--from generic to disease-specific
    George A Wells
    Cardiovascular Research Methods Centre, University of Ottawa Heart Institute, 40 Ruskin Street, Ottawa, Ontario, Canada
    J Rheumatol Suppl 88:2-6. 2011
    ..Several examples of generic and disease-specific instruments commonly used to evaluate HRQOL in patients with immune-mediated inflammatory diseases (IMID) are provided...
  33. ncbi request reprint Calcium supplementation on bone loss in postmenopausal women
    B Shea
    Institute of Population Health, University of Ottawa, 1 Stewart Street, Ottawa, K1N 6N5, Ontario, Canada
    Cochrane Database Syst Rev . 2003
    ..The Food and Drug Administration in the US has permitted a bone health claim for calcium-rich foods, and the NIH in its Consensus Development Process approved a statement that high calcium intake reduces the risk of osteoporosis...
  34. ncbi request reprint Low level laser therapy (classes I, II and III) in the treatment of rheumatoid arthritis
    L Brosseau
    School of Rehabilitation Sciences, Faculty of Health Sciences, University of Ottawa, 451 Smyth Road, Ottawa, Ontario, Canada, K1H 8M5
    Cochrane Database Syst Rev . 2000
    ..The effect is not thermal, but rather related to photochemical reactions in the cells. The effectiveness of LLLT for rheumatoid arthritis is still controversial...
  35. ncbi request reprint Low level laser therapy (Classes I, II and III) for treating rheumatoid arthritis
    L Brosseau
    University of Ottawa, School of Rehabilitation Sciences, Faculty of Health Sciences, 451 Smyth Road, Ottawa, Ontario, Canada K1H 8M5
    Cochrane Database Syst Rev . 2005
    ..The effect is not thermal, but rather related to photochemical reactions in the cells. The effectiveness of LLLT for rheumatoid arthritis is still controversial. This review is an update of the original review published in October 1998...
  36. ncbi request reprint Low level laser therapy (Classes I, II and III) for treating osteoarthritis
    L Brosseau
    School of Rehabilitation Sciences, University of Ottawa, 451 Smyth Road, Ottawa, Ontario, Canada, K1H 8M5
    Cochrane Database Syst Rev . 2003
    ..The effect is not thermal, but rather related to photochemical reactions in the cells. LLLT was introduced as an alternative non-invasive treatment for OA about 10 years ago, but its effectiveness is still controversial...
  37. ncbi request reprint Etidronate for treating and preventing postmenopausal osteoporosis
    A Cranney
    Medicine Rheumatology, Ottawa Hospital, Civic Campus, 461, 737 Parkdale Ave, Ottawa, Ontario, Canada, K1Y 1J8
    Cochrane Database Syst Rev . 2001
    ..To systematically review the efficacy of etidronate on bone density, fractures and toxicity in postmenopausal women...
  38. ncbi request reprint Low level laser therapy (classes I, II and III) for the treatment of osteoarthritis
    L Brosseau
    School of Rehabilitation Sciences, Faculty of Health Sciences, University of Ottawa, 451 Smyth Road, Ottawa, Ontario, Canada, K1H 8M5
    Cochrane Database Syst Rev . 2000
    ..The effect is not thermal, but rather related to photochemical reactions in the cells. LLLT was introduced as an alternative non-invasive treatment for OA about 10 years ago, but its effectiveness is still controversial...
  39. ncbi request reprint WITHDRAWN: Low level laser therapy (Classes III) for treating osteoarthritis
    L Brosseau
    University of Ottawa, School of Rehabilitation Sciences, Faculty of Health Sciences, 451 Smyth Road, Ottawa, Ontario, Canada, K1H 8M5
    Cochrane Database Syst Rev . 2007
    ..LLLT was introduced as an alternative non-invasive treatment for OA about 30 years ago, but its effectiveness has to be examined more closely, especially in the treatment of OA...
  40. ncbi request reprint Therapeutic ultrasound for treating patellofemoral pain syndrome
    L Brosseau
    School of Rehabilitation Sciences, University of Ottawa, Department of Rehabilitation Sciences, 451 Smyth Road, Ottawa, Ontario, Canada, K1H 8M5
    Cochrane Database Syst Rev . 2001
    ..Therapeutic ultrasound is one of several rehabilitation interventions suggested for the management of pain due to patellofemoral pain syndrome...
  41. ncbi request reprint The psychometric properties of patient preferences in osteoporosis
    A Cranney
    Department of Medicine, Ottawa Hospital, Ontario, Canada
    J Rheumatol 28:132-7. 2001
    ..The feeling thermometer and standard gamble appear to be related to different aspects of health related quality of life. Both instruments were sensitive to change over a 2 month period...
  42. ncbi request reprint Discrimination of changes in osteoporosis outcomes
    A Cranney
    Department of Medicine, Ottawa Hospital, Loeb Research Institute, Ontario, Canada
    J Rheumatol 28:413-21. 2001
    ..Furthermore, these MCID will likely be different for individual patients seen in clinical practice than for individuals in a clinical trial...
  43. ncbi request reprint Deep transverse friction massage for treating tendinitis
    L Brosseau
    School of Rehabilitation Sciences, University of Ottawa, Department of Rehabilitation Sciences, 451 Smyth Road, Ottawa, Ontario, Canada, K1H 8M5
    Cochrane Database Syst Rev . 2002
    ..Deep transverse friction massage (DTFM) is one of several physiotherapy interventions suggested for the management of pain due to iliotibial band friction syndrome (ITBFS)...
  44. ncbi request reprint Prazosin for Raynaud's phenomenon in progressive systemic sclerosis
    J Pope
    Medicine Division of Rheumatology, University of Western Ontario, LHSC South Campus, 375 South Street Room 309 Colborne Bldg, London, Ontario, Canada, N6A 4G5
    Cochrane Database Syst Rev . 2000
    ..To determine the effects and toxicity of prazosin versus placebo proposed for the treatment of Raynaud's phenomenon (RP) in scleroderma...
  45. ncbi request reprint Cyclofenil for Raynaud's phenomenon in progressive systemic sclerosis
    J Pope
    Medicine Division of Rheumatology, University of Western Ontario, LHSC South Campus, 375 South Street Room 309 Colborne Bldg, London, Ontario, Canada, N6A 4G5
    Cochrane Database Syst Rev . 2000
    ..To assess the effects and toxicity of Cyclofenil versus placebo for the treatment of Raynaud's phenomenon (RP) in scleroderma...
  46. ncbi request reprint WITHDRAWN: Risedronate for the prevention and treatment of postmenopausal osteoporosis
    A Cranney
    Ottawa Hospital, Division of Rheumatology, 1053 Carling Ave, Ottawa, Ontario, Canada, K1Y 4E9
    Cochrane Database Syst Rev . 2007
    ..First and second generation bisphosphonates are known to have gastrointestinal side-effects and risedronate may be better tolerated...
  47. ncbi request reprint Ketanserin for Raynaud's phenomenon in progressive systemic sclerosis
    J Pope
    Medicine Division of Rheumatology, University of Western Ontario, LHSC South Campus, 375 South Street Room 309 Colborne Bldg, London, Ontario, Canada, N6A 4G5
    Cochrane Database Syst Rev . 2000
    ..To assess the effects and toxicity of the following agent: ketanserin versus placebo proposed for the treatment of Raynaud's phenomenon (RP) in scleroderma...
  48. ncbi request reprint WITHDRAWN: Calcium supplementation on bone loss in postmenopausal women
    B Shea
    University of Ottawa, Institute of Population Health, 1 Stewart St, Room 312, Ottawa, Onatrio, Canada K1N 6N5
    Cochrane Database Syst Rev . 2007
    ..The Food and Drug Administration in the US has permitted a bone health claim for calcium-rich foods, and the NIH in its Consensus Development Process approved a statement that high calcium intake reduces the risk of osteoporosis...
  49. ncbi request reprint Deep transverse friction massage for treating tendinitis
    L Brosseau
    School of Rehabilitation Sciences, University of Ottawa, 451 Smyth, Room 3060, Ottawa, ON, Canada, K1H8M5
    Cochrane Database Syst Rev . 2002
    ..Deep transverse friction massage (DTFM) is one of several physiotherapy interventions suggested for the management of tendinitis pain...
  50. ncbi request reprint Thermotherapy for treating rheumatoid arthritis
    V Robinson
    Institute of Population Health, University of Ottawa, 1 Stewart Street, Ottawa, Ontario, Canada, K1N 6N5
    Cochrane Database Syst Rev . 2002
    ..Thermotherapy is often used as adjunct in the treatment of rheumatoid arthritis (RA) by rehabilitation specialists...
  51. ncbi request reprint Transcutaneous electrical nerve stimulation for knee osteoarthritis
    M Osiri
    Department of Medicine, Ottawa Hospital, General Campus, 501 Smyth Road, LM 12, Ottawa General Hospital, Ottawa, Ontario, Canada, K1H 8L6
    Cochrane Database Syst Rev . 2000
    ..A number of trials evaluating the efficacy of TENS in OA have been published...
  52. ncbi request reprint WITHDRAWN: Etidronate for treating and preventing postmenopausal osteoporosis
    A Cranney
    Ottawa Hospital, Division of Rheumatology, 1053 Carling Ave, Ottawa, Ontario, Canada, K1Y 4E9
    Cochrane Database Syst Rev . 2007
    ..Osteoporosis is a clinical syndrome of reduced bone mass and increased fracture susceptibility. There are now a number of options, including etidronate which can decrease the risk of fractures...
  53. ncbi request reprint Prevention of NSAID-induced gastroduodenal ulcers
    A Rostom
    University of Ottawa Department of Medicine, A1 Endoscopy Unit, Ottawa Hospital Civic Campus, 1053 Carling Ave, Ottawa, Ontario, Canada, K1Y 4E9
    Cochrane Database Syst Rev . 2000
    ..However, there is overwhelming evidence linking these agents to a variety of gastrointestinal (GI) toxicities...
  54. ncbi request reprint Prevention of chronic NSAID induced upper gastrointestinal toxicity
    A Rostom
    University of Ottawa Department of Medicine, A1 Endoscopy Unit, Ottawa Hospital Civic Campus, 1053 Carling Ave, Ottawa, Ontario, Canada, K1Y 4E9
    Cochrane Database Syst Rev . 2000
    ..However, there is overwhelming evidence linking these agents to a variety of gastrointestinal (GI) toxicities...
  55. ncbi request reprint Prevention of NSAID-induced gastroduodenal ulcers
    A Rostom
    University of Ottawa Department of Medicine, A1 Endoscopy Unit, Ottawa Hospital Civic Campus, 1053 Carling Ave, Ottawa, Ontario, Canada, K1Y 4E9
    Cochrane Database Syst Rev . 2002
    ..However, there is overwhelming evidence linking these agents to a variety of gastrointestinal (GI) toxicities...
  56. ncbi request reprint Thermotherapy for treating rheumatoid arthritis
    V Welch
    Clinical Epidemiology Unit, Ottawa Hospital Civic Campus F6, 1053 Carling Avenue, Ottawa, Ontario, Canada, K1Y 4E9
    Cochrane Database Syst Rev . 2001
    ..Heat and cold therapy are often used as adjuncts in the treatment of rheumatoid arthritis by rehabilitation specialists...
  57. ncbi request reprint Therapeutic ultrasound for osteoarthritis of the knee
    V Welch
    Clinical Epidemiology Unit, Ottawa Hospital Civic Campus F6, 1053 Carling Avenue, Ottawa, Ontario, Canada, K1Y 4E9
    Cochrane Database Syst Rev . 2001
    ..Therapeutic ultrasound is one of several physical therapy modalities suggested for the management of pain and loss of function due to OA...
  58. ncbi request reprint Transcutaneous electrical nerve stimulation (TENS) for chronic low back pain
    S Milne
    School of Rehabilitation Sciences, Faculty of Health Sciences, University of Ottawa, 451 Smyth Road, Ottawa, Ontario, Canada, K1H 8M5
    Cochrane Database Syst Rev . 2001
    ..However, despite its widespread use, the effectiveness of TENS is still controversial...
  59. ncbi request reprint Acupuncture and electroacupuncture for the treatment of RA
    L Casimiro
    School of Rehabilitation Sciences, University of Ottawa, 451 Smyth Road, Ottawa, Ontario, Canada, K1H 8M5
    Cochrane Database Syst Rev . 2002
    ..Once the needles are inserted in some of the appropriate points, endorphins, morphine-like substances, have been shown to be released in the patient's system, thus inducing local or generalised analgesia...
  60. ncbi request reprint Thermotherapy for treating rheumatoid arthritis
    V Welch
    Clinical Epidemiology Unit, Ottawa Hospital Civic Campus F6, 1053 Carling Avenue, Ottawa, Ontario, Canada, K1Y 4E9
    Cochrane Database Syst Rev . 2000
    ..Heat and cold therapy are often used as adjuncts in the treatment of rheumatoid arthritis by rehabilitation specialists...
  61. ncbi request reprint Glucosamine therapy for treating osteoarthritis
    T E Towheed
    Medicine, Community Health and Epidemiology, Queen s University, Room 2066 Etherington Hall, Queen s University, Kingston, Ontario, Canada, K7L 3N6
    Cochrane Database Syst Rev . 2005
    ..Osteoarthritis (OA) is the most common form of arthritis, and it is often associated with significant disability and an impaired quality of life...
  62. ncbi request reprint Thermotherapy for treating rheumatoid arthritis
    V Robinson
    Institute of Population Health, University of Ottawa, 1 Stewart Street, Ottawa, Ontario, Canada, K1N 6N5
    Cochrane Database Syst Rev . 2002
    ..Thermotherapy is often used as adjunct in the treatment of rheumatoid arthritis (RA) by rehabilitation specialists...
  63. ncbi request reprint Individualized functional priority approach to the assessment of health related quality of life in rheumatology
    J Clinch
    Clinical Epidemiology Unit, The Ottawa Hospital, and the Faculty of Medicine, University of Ottawa, Ontario, Canada
    J Rheumatol 28:445-51. 2001
    ..Of particular interest are the scoring methods and responsiveness of these questionnaires, both necessary variables for defining minimal clinically important differences...
  64. ncbi request reprint Minimal clinically important differences: review of methods
    G Wells
    Department of Epidemiology and Community Medicine, Faculty of Medicine, University of Ottawa, Ontario, Canada
    J Rheumatol 28:406-12. 2001
    ..Development of methods that focus on individuals should be a goal of the future...
  65. ncbi request reprint Electromagnetic fields for the treatment of osteoarthritis
    J Hulme
    Cochrane Collaborating Center, Center for Global Health, Institute of Population Health University of Ottawa, 1 Stewart Street, Ottawa, Ontario, Canada, K1N 6N5
    Cochrane Database Syst Rev . 2002
    ..As the focus for osteoarthritis (OA) treatment shifts away from drug therapy, we consider the effectiveness of pulsed electric stimulation which is proven to stimulate cartilage growth on the cellular level...
  66. ncbi request reprint Continuous passive motion following total knee arthroplasty
    S Milne
    School of Rehabilitation Sciences, University of Ottawa, 451 Smyth Road, Ottawa, Ontario, Canada, K1H 8M5
    Cochrane Database Syst Rev . 2003
    ..Post-surgery rehabilitation protocols often include continuous passive motion (CPM). However, CPM protocols vary considerably amongst institutions...
  67. ncbi request reprint Exercise for preventing and treating osteoporosis in postmenopausal women
    D Bonaiuti
    Institute of Population Health, University of Ottawa, 1 Stewart Street, Ottawa, Ontario, Canada, K1N 6N5
    Cochrane Database Syst Rev . 2002
    ..g. estrogen and bisphosphonate) or bone formation agents (e.g. fluoride and PTH). The value of exercise as an intervention for the prevention of postmenopausal bone loss is a controversial subject...
  68. ncbi request reprint A meta-analysis of etidronate for the treatment of postmenopausal osteoporosis
    A Cranney
    Department of Medicine and Clinical Epidemiology, Loeb Research Institute, University of Ottawa, Canada
    Osteoporos Int 12:140-51. 2001
    ..Etidronate increases bone density in the lumbar spine and femoral neck for up to 4 years. The pooled estimates of fracture reduction with etidronate suggest a reduction in vertebral fractures, but no effect on nonvertebral fractures...
  69. ncbi request reprint Low level laser therapy for osteoarthritis and rheumatoid arthritis: a metaanalysis
    L Brosseau
    Physiotherapy Program, School of Rehabilitation Sciences, Faculty of Health Sciences, University of Ottawa, Ontario, Canada
    J Rheumatol 27:1961-9. 2000
    ..Low level laser therapy (LLLT) was introduced as an alternative noninvasive treatment for RA and OA about 10 years ago, but its effectiveness is still controversial. We assessed the effectiveness of LLLT in the treatment of RA and OA...
  70. ncbi request reprint How Canadian and US rheumatologists treat moderate or aggressive rheumatoid arthritis: a survey
    A Maetzel
    Healthcare Research Division, Arthritis and Immune Disorder Research Centre, Toronto, Ontario, Canada
    J Rheumatol 25:2331-8. 1998
    ..To determine which second line agents Canadian and US rheumatologists use to treat patients with active rheumatoid arthritis (RA)...
  71. ncbi request reprint Intensity of exercise for the treatment of osteoarthritis
    L Brosseau
    School of Rehabilitation Sciences, University of Ottawa, 451 Smyth Road, Ottawa, Ontario, Canada, K1H 8M5
    Cochrane Database Syst Rev . 2003
    ..Therapeutic exercise is used as one modality to treat people with osteoarthritis (OA)...
  72. ncbi request reprint Fluoride for treating postmenopausal osteoporosis
    D Haguenauer
    Clinical Epidemiologist, 135 Riverdale Avenue, Ottawa, Ontario, Canada, K1S 1R1
    Cochrane Database Syst Rev . 2000
    ..To assess the efficacy of fluoride therapy on bone loss, vertebral and non-vertebral fractures and side effects in postmenopausal women...
  73. ncbi request reprint Do silicone breast implants cause rheumatologic disorders? A systematic review for a court-appointed national science panel
    P Tugwell
    Centre for Global Health, University of Ottawa, Institute of Population Health, Ontario, Canada
    Arthritis Rheum 44:2477-84. 2001
    ..Therefore, we performed a systematic review of published studies on the association between silicone breast implants and systemic connective tissue disorders...
  74. ncbi request reprint Acupuncture and electroacupuncture for the treatment of rheumatoid arthritis
    L Casimiro
    University of Ottawa, School of Rehabilitation Sciences, 451 Smyth Road, Ottawa, Ontario, Canada K1H 8M5
    Cochrane Database Syst Rev . 2005
    ..This review is an update of the original review published in July 2002...
  75. ncbi request reprint Cyclosporine for rheumatoid arthritis
    G Wells
    Department of Epidemiology and Community Medicine, University of Ottawa, 451 Smyth Road, Room 3227, Ottawa, Ontario, Canada, K1H 8M5
    Cochrane Database Syst Rev . 2000
    ..To estimate the short-term (up to one year) effects of cyclosporine for rheumatoid arthritis...
  76. ncbi request reprint Pharmacotherapy for Behcet's syndrome
    A Saenz
    Clinical Epidemiology Unit C406, Loeb Research Institute, Ottawa Hospital Civic Site, 1053 Carling Avenue, Ottawa, Ontario, Canada, K1Y 4E9
    Cochrane Database Syst Rev . 2000
    ..To determine the effects of available pharmacological interventions in treating the different clinical features of Behcet's syndrome...
  77. ncbi request reprint The prevention of chronic NSAID induced upper gastrointestinal toxicity: a Cochrane collaboration metaanalysis of randomized controlled trials
    A Rostom
    Department of Medicine, University of Ottawa, Ontario, Canada
    J Rheumatol 27:2203-14. 2000
    ..To review the effectiveness of common interventions for the prevention of nonsteroidal antiinflammatory drug (NSAID) induced upper gastrointestinal (GI) toxicity...
  78. ncbi request reprint Low disease activity state in rheumatoid arthritis: concepts and derivation of minimal disease activity
    G Wells
    Department of Epidemiology and Community Medicine, University of Ottawa, Ottawa, Ontario, Canada
    Clin Exp Rheumatol 24:S-52-9. 2006
    ....
  79. ncbi request reprint Acetaminophen for osteoarthritis
    T E Towheed
    Medicine and Community Health and Epidemiology, Queen s University, Room 2066, Etherington Hall, Department of Medicine, Queen s University, Kingston, Ontario, Canada, K7L 3N6
    Cochrane Database Syst Rev . 2003
    ....
  80. ncbi request reprint Structured exercise improves physical functioning in women with stages I and II breast cancer: results of a randomized controlled trial
    R Segal
    Department of Medical Oncology, Ottawa Regional Cancer Centre, Ottawa, Ontario, Canada
    J Clin Oncol 19:657-65. 2001
    ....
  81. ncbi request reprint The impact of risk on preference values: implications for evaluations of postmenopausal osteoporosis therapy
    D Coyle
    Departments of Medicine and Epidemiology and Community Medicine, University of Ottawa, Ottawa, Ontario, Canada
    Value Health 4:385-91. 2001
    ..In this way, we were able to determine the incremental effect of changes in risks of each disease on preference values...
  82. ncbi request reprint Analgesia and non-aspirin, non-steroidal anti-inflammatory drugs for osteoarthritis of the hip
    T Towheed
    Medicine and of Community Health and Epidemiology, Queen s University, Etherington Hall Room 2066, Kingston, Ontario, Canada, K7L 3N6
    Cochrane Database Syst Rev . 2000
    ..To review all randomized trials of analgesics and anti-inflammatory therapy in osteoarthritis (OA) of the hip. To determine which non-steroidal, anti-inflammatory drug (NSAID) is the most effective, and which NSAID is the most toxic...
  83. ncbi request reprint Iloprost and cisaprost for Raynaud's phenomenon in progressive systemic sclerosis
    J Pope
    Medicine Division of Rheumatology, University of Western Ontario, LHSC South Campus, 375 South Street Room 309 Colborne Bldg, London, Ontario, Canada, N6A 4G5
    Cochrane Database Syst Rev . 2000
    ..To assess the effects and toxicity of the following agents:Prostaglandin analogues together with other agents proposed for the treatment of Raynaud's phenomenom (RP) in scleroderma...
  84. pmc Cancer antigen 125 in ovarian cancer surveillance: a decision analysis model
    M L Hopkins
    Division of Gynecologic Oncology, University of Ottawa, Ottawa, Ontario
    Curr Oncol 14:167-72. 2007
    ..The model demonstrates that preferences and perspective can influence decisions in cancer care...
  85. ncbi request reprint School feeding for improving the physical and psychosocial health of disadvantaged elementary school children
    E A Kristjansson
    Institute of Population Health, School of Psychology and Centre for Global Health, 1 Stewart Street, Ottawa, Ontario, Canada, K1N 6N5
    Cochrane Database Syst Rev . 2007
    ..Early malnutrition and/or micronutrient deficiencies can adversely affect physical, mental, and social aspects of child health. School feeding programs are designed to improve attendance, achievement, growth, and other health outcomes...
  86. ncbi request reprint Acetaminophen for osteoarthritis
    T E Towheed
    Queen s University, Medicine and of Community Health and Epidemiology, Etherington Hall Room 2066, Kingston, Ontario, Canada, K7L 3N6
    Cochrane Database Syst Rev . 2006
    ..The comparative safety of acetaminophen and NSAIDs is also important to consider. This update to the original 2003 review includes nine additional RCTs...
  87. ncbi request reprint Establishing reference intervals for DPC's free testosterone radioimmunoassay
    D S Ooi
    Division of Biochemistry, Ottawa Civic Hospital, Ontario, Canada
    Clin Biochem 31:15-21. 1998
    ..To establish reference intervals for serum free testosterone for DPC's Free Testosterone assay...
  88. doi request reprint A comparison of aprotinin and lysine analogues in high-risk cardiac surgery
    Dean A Fergusson
    Ottawa Health Research Institute, Ottawa, Canada
    N Engl J Med 358:2319-31. 2008
    ..We sought to determine whether aprotinin was superior to either tranexamic acid or aminocaproic acid in decreasing massive postoperative bleeding and other clinically important consequences...
  89. ncbi request reprint Comparison of the efficacy and safety of finasteride in older versus younger men with benign prostatic hyperplasia
    S A Kaplan
    Columbia Presbyterian Medical Center, New York, New York 10032, USA
    Urology 57:1073-7. 2001
    ..In addition, the safety profile of finasteride in both older and younger men is similar and no drug interactions of clinical importance were observed...
  90. doi request reprint Reporting disease activity in clinical trials of patients with rheumatoid arthritis: EULAR/ACR collaborative recommendations
    D Aletaha
    Division of Rheumatology, Medical University of Vienna, Vienna, Austria
    Ann Rheum Dis 67:1360-4. 2008
    ..To make recommendations on how to report disease activity in clinical trials of rheumatoid arthritis (RA) endorsed by the European League Against Rheumatism (EULAR) and the American College of Rheumatology (ACR)...
  91. doi request reprint Methods of deriving EULAR/ACR recommendations on reporting disease activity in clinical trials of patients with rheumatoid arthritis
    T Karonitsch
    Division of Rheumatology, Medical University of Vienna, Vienna, Austria
    Ann Rheum Dis 67:1365-73. 2008
    ....
  92. doi request reprint Reporting disease activity in clinical trials of patients with rheumatoid arthritis: EULAR/ACR collaborative recommendations
    D Aletaha
    Medical University of Vienna, Vienna, Austria
    Arthritis Rheum 59:1371-7. 2008
    ..To make recommendations on how to report disease activity in clinical trials of rheumatoid arthritis (RA) endorsed by the European League Against Rheumatism (EULAR) and the American College of Rheumatology (ACR)...