Curtis A Suttle
Affiliation: University of British Columbia
- Sequence analysis of marine virus communities reveals that groups of related algal viruses are widely distributed in natureSteven M Short
Department of Botany, University of British Columbia, 6720 University Boulevard, Vancouver, British Columbia, Canada, V6T 1Z4
Appl Environ Microbiol 68:1290-6. 2002..DGGE is a powerful tool for genetically fingerprinting natural virus communities and may be used to examine how specific components of virus communities respond to experimental manipulations...
- Marine viruses--major players in the global ecosystemCurtis A Suttle
University of British Columbia, Departments of Earth and Ocean Sciences, Botany, and Microbiology and Immunology, 1461 BioSciences, 6270 University Boulevard, Vancouver, British Columbia V6T 1Z4, Canada
Nat Rev Microbiol 5:801-12. 2007..Probing this vast reservoir of genetic and biological diversity continues to yield exciting discoveries...
- Viruses in the seaCurtis A Suttle
Department of Chemistry, University of California, Berkeley and the Molecular Foundry, Lawrence Berkeley National Laboratory, Berkeley, California 94720, USA
Nature 437:356-61. 2005..Our understanding of the effect of viruses on global systems and processes continues to unfold, overthrowing the idea that viruses and virus-mediated processes are sidebars to global processes...
- Phylogenetic analysis indicates evolutionary diversity and environmental segregation of marine podovirus DNA polymerase gene sequencesJessica M Labonté
Departments of Microbiology and Immunology, University of British Columbia, Vancouver, Canada
Appl Environ Microbiol 75:3634-40. 2009....
- Metagenomic analysis of coastal RNA virus communitiesAlexander I Culley
Department of Botany, University of British Columbia, 3529 6270 University Boulevard, Vancouver, BC V6T 1Z4, Canada
Science 312:1795-8. 2006..Our results show that the oceans are a reservoir of previously unknown RNA viruses...
- The complete genomes of three viruses assembled from shotgun libraries of marine RNA virus communitiesAlexander I Culley
University of British Columbia, Department of Botany, Vancouver, BC, Canada
Virol J 4:69. 2007..The present contribution comparatively analyzes these genomes with respect to representative viruses from established viral taxa...
- Identification of freshwater Phycodnaviridae and their potential phytoplankton hosts, using DNA pol sequence fragments and a genetic-distance analysisJessica L Clasen
Department of Earth and Ocean Sciences, University of British Columbia, Vancouver, British Columbia, Canada
Appl Environ Microbiol 75:991-7. 2009..Monoraphidium sp., and Cyclotella sp. This approach should help to unravel the relationships between viruses in the environment and the phytoplankton hosts they infect...
- Previously unknown and highly divergent ssDNA viruses populate the oceansJessica M Labonté
Department of Microbiology and Immunology, University of British Columbia, Vancouver, BC, Canada
ISME J 7:2169-77. 2013..Some of these encoded putative replication and coat proteins that had similarity to sequences from viruses infecting eukaryotes, suggesting that these were likely from viruses infecting eukaryotic phytoplankton and zooplankton. ..
- Genetic richness of vibriophages isolated in a coastal environmentAndré M Comeau
Department of Microbiology and Immunology, University of British Columbia, Vancouver, Canada V6T 1Z4
Environ Microbiol 8:1164-76. 2006..Therefore, the VpV population within the Strait of Georgia is a highly diverse mixture of phenotypes and genotypes...
- Genome sequence and characterization of a virus (HaRNAV) related to picorna-like viruses that infects the marine toxic bloom-forming alga Heterosigma akashiwoAndrew S Lang
Department of Earth and Ocean Sciences, University of British Columbia, Vancouver, B C, Canada V6T 1Z4
Virology 320:206-17. 2004..The combination of genome structure and sequence relationships to other viruses suggests that HaRNAV is the first member of a proposed new virus family (Marnaviridae), related to picorna-like viruses...
- Distribution, genetic richness and phage sensitivity of Vibrio spp. from coastal British ColumbiaAndré M Comeau
Department of Microbiology and Immunology, University of British Columbia, Vancouver, BC, Canada, V6T 1Z4
Environ Microbiol 9:1790-800. 2007..were widespread in the areas investigated, the results show that there is segregation of bacterial host strains in different environments, under differing selection pressures, which ultimately will affect in situ phage production...
- Effects of environmental variation and spatial distance on bacteria, archaea and viruses in sub-polar and arctic watersChristian Winter
Department of Earth and Ocean Sciences, The University of British Columbia, Vancouver, British Columbia, Canada
ISME J 7:1507-18. 2013....
- Isolation independent methods of characterizing phage communities 1: strain typing using fingerprinting methodsClemens Pausz
Department of Earth and Ocean Sciences, University of British Columbia, Vancouver, BC, Canada
Methods Mol Biol 502:255-78. 2009..Finger printing techniques are a relatively fast and cheap tool to assess the diversity of environmental viruses. Together, PFGE and DGGE provide useful tools to study viral ecology in natural habitats...
- Giant virus with a remarkable complement of genes infects marine zooplanktonMatthias G Fischer
Department of Microbiology, University of British Columbia, Vancouver, BC, Canada V6T 1Z4
Proc Natl Acad Sci U S A 107:19508-13. 2010..CroV is a highly complex marine virus and the only virus studied in genetic detail that infects one of the major groups of predators in the oceans...
- A persistent, productive, and seasonally dynamic vibriophage population within Pacific oysters (Crassostrea gigas)André M Comeau
Department of Earth and Ocean Sciences, Rm 1461, BioSciences Bldg, 6270 University Blvd, University of British Columbia, Vancouver, British Columbia V6T 1Z4, Canada
Appl Environ Microbiol 71:5324-31. 2005..parahaemolyticus in oysters and in the water column. Furthermore, seasonal shifts in patterns of host range provide strong evidence that the composition of the virus community changes during winter...
- High diversity of unknown picorna-like viruses in the seaAlexander I Culley
Department of Botany, University of British Columbia, Vancouver, British Columbia, V6T 1Z4, Canada
Nature 424:1054-7. 2003....
- A virophage at the origin of large DNA transposonsMatthias G Fischer
Department of Microbiology and Immunology, 1365 2350 Health Sciences Mall, University of British Columbia, Vancouver V6T 1Z3, Canada
Science 332:231-4. 2011....
- The viriosphere, diversity, and genetic exchange within phage communitiesEmma Hambly
Department of Earth and Ocean Sciences, University of British Columbia, 1461 Biological Sciences, 6270 University Blvd, Vancouver, BC V6T 1Z4, Canada
Curr Opin Microbiol 8:444-50. 2005..These observations support the idea that a primary role of host populations in phage ecology and evolution is to serve as vectors for genetic exchange...
- The use of degenerate-primed random amplification of polymorphic DNA (DP-RAPD) for strain-typing and inferring the genetic similarity among closely related virusesAndré M Comeau
Department of Microbiology and Immunology, University of British Columbia, Vancouver, Canada V6T 1Z4
J Virol Methods 118:95-100. 2004..These findings describe a rapid, PCR-based tool for strain-typing viral isolates that allows inferences to be made on genetic relatedness within groups of closely related viruses...
- DNA polymerase gene sequences indicate western and forest tent caterpillar viruses form a new taxonomic group within baculovirusesCydney B Nielsen
Department of Microbiology and Immunology, University of British Columbia, BC, V6T 1Z4, Vancouver, Canada
J Invertebr Pathol 81:131-47. 2002..7-86.1% nucleotide identity). Both maximum parsimony and maximum likelihood phylogenetic analyses support placement of McplMNPV and MadiMNPV in a clade that is distinct from other groups of baculoviruses...
- Accurate estimation of viral abundance by epifluorescence microscopyKevin Wen
Department of Microbiology and Immunology, University of British Columbia, Vancouver, BC V6T 1Z4, Canada
Appl Environ Microbiol 70:3862-7. 2004..If protocols outlined in this paper are followed, EFM yields accurate estimates of viral abundance...
- Viruses Infecting a Freshwater Filamentous Cyanobacterium (Nostoc sp.) Encode a Functional CRISPR Array and a Proteobacterial DNA Polymerase BCaroline Chénard
Department of Earth Ocean and Atmospheric Sciences, University of British Columbia, Vancouver, British Columbia, Canada
MBio 7:. 2016..strain PCC 7524. The Nostoc cyanophages reveal a history of gene transfers between filamentous cyanobacteria and their viruses that have helped to forge the evolutionary trajectory of this previously unrecognized group of phages...
- The virion of Cafeteria roenbergensis virus (CroV) contains a complex suite of proteins for transcription and DNA repairMatthias G Fischer
Department of Microbiology and Immunology, University of British Columbia, Vancouver, Canada V6T 1Z4 Electronic address
Virology 466:82-94. 2014..The overlapping virion proteome of CroV and Mimivirus reveals a set of conserved virion protein functions that were presumably present in the last common ancestor of the Mimiviridae. ..
- The sensitivity of massively parallel sequencing for detecting candidate infectious agents associated with human tissueRichard A Moore
Genome Sciences Centre, BC Cancer Agency, Vancouver, British Columbia, Canada
PLoS ONE 6:e19838. 2011..With current sequencing platforms approaching outputs of one billion reads per run, this is a highly sensitive method for detecting putative infectious agents associated with human tissues...
- Global-scale processes with a nanoscale drive: the role of marine virusesCorina P D Brussaard
Department of Biological Oceanography, Royal Netherlands Institute for Sea Research NIOZ, Texel, The Netherlands
ISME J 2:575-8. 2008
- The marine viromes of four oceanic regionsFlorent E Angly
Department of Biology, San Diego State University, San Diego, California, USA
PLoS Biol 4:e368. 2006..These results support the idea that viruses are widely dispersed and that local environmental conditions enrich for certain viral types through selective pressure...
- Nearly identical bacteriophage structural gene sequences are widely distributed in both marine and freshwater environmentsCindy M Short
Department of Earth and Department of Ocean Sciences, University of British of Columbia, 6270 University Blvd, Vancouver, British Columbia, Canada V6T 1Z4
Appl Environ Microbiol 71:480-6. 2005..Moreover, the amplification of g20 products from deep in the cyanobacterium-sparse Chuckchi Sea suggests that this primer set targets bacteriophages other than those infecting cyanobacteria...
- Marine T4-type bacteriophages, a ubiquitous component of the dark matter of the biosphereJonathan Filee
Laboratoire de Microbiologie et Genetique Moleculaire, Centre National de la Recherche Scientifique, Unité Mixte de Recherche 5100, 31062, Toulouse, Cedex 9, France
Proc Natl Acad Sci U S A 102:12471-6. 2005..These data indicate that the host range of T4-type phages is much broader than previously imagined and that the laboratory isolate T4 belongs to a phage family that is extraordinarily widespread and diverse in the biosphere...
- The complete sequence of marine bacteriophage VpV262 infecting vibrio parahaemolyticus indicates that an ancestral component of a T7 viral supergroup is widespread in the marine environmentStephen C Hardies
Department of Biochemistry, MSC 7760, The University of Texas Health Science Center at San Antonio, 7703 Floyd Curl Dr, San Antonio, TX 78229 3900, USA
Virology 310:359-71. 2003..In the early and replicative segments, these phages have participated in extensive interchange with the viral gene pool. VpV262 carries a different replicative module than SIO1 and the T7-like phages...
- [T4-type bacteriophages: ubiquitous components of the "dark matter" of the biosphere]Jonathan Filee
Med Sci (Paris) 22:111-2. 2006
- Estimation of biologically damaging UV levels in marine surface waters with DNA and viral dosimetersSteven W Wilhelm
Photochem Photobiol 76:268-73. 2002..1% (ca 200-300 dimers Mb(-1) DNA)...