Affiliation: University of Manitoba
- Radiological imaging in pneumonia: recent innovationsSat Sharma
Sections of Pulmonary and Critical Care Medicine, University of Manitoba, St Boniface General Hospital, Canada
Curr Opin Pulm Med 13:159-69. 2007..Radiological imaging plays a prominent role in the evaluation and treatment of patients with pneumonia. This paper reviews recent innovations in the radiologic diagnosis and management of suspected pulmonary infections...
- Computed tomography for the diagnosis of infectious diseases of the chestSat Sharma
Professor and Head University of Manitoba, St Boniface General Hospital, Section of Respirology, Department of Internal Medicine, BG034, 409 Tache Avenue, Winnipeg MB, R2H 2A6, Canada 204 237 2217 204 231 1927
Expert Opin Med Diagn 2:1247-62. 2008..The greatest value of CT is when the radiograph is normal, findings are equivocal, and to differentiate infection from non-infectious disorders...
- Is obesity associated with an increased risk for airway hyperresponsiveness and development of asthma?Sat Sharma
Section of Respirology, Department of Internal Medicine, University of Manitoba, Winnipeg, MB
Allergy Asthma Clin Immunol 4:51-8. 2008..05, p < .005). The odds ratio increased from 1.86 (95% CI 1.27-1.76; p = .0012) for class I to 2.61 (95% CI 1.48-4.60; p = .0006) for class III. Obesity was found to be associated with AHR and appears to be a risk factor for asthma...
- Cardiac imaging in myocardial sarcoidosis and other cardiomyopathiesSat Sharma
Department of Internal Medicine, University of Manitoba, St Boniface General Hospital, Winnipeg, Manitoba, Canada
Curr Opin Pulm Med 15:507-12. 2009..An up-to-date review of the role of various imaging modalities in the evaluation of cardiac sarcoidosis and other cardiomyopathies is presented...
- Anabolic steroids in COPD: a review and preliminary results of a randomized trialS Sharma
Departments of Internal Medicine and Radiology, University of Manitoba, Winnipeg, Canada
Chron Respir Dis 5:169-76. 2008..Administration of anabolic steroids (nandrolone decanoate) outside a dedicated rehabilitation program did not lead to either weight gain, improvement in physiological function, or better quality of life in patients with severe COPD...
- Spirometry and respiratory muscle function during ascent to higher altitudesSat Sharma
Sections of Pulmonary and Critical Care Medicine, Department of Internal Medicine, University of Manitoba, Winnipeg, Manitoba, Canada
Lung 185:113-21. 2007..Initial transient increases in parameters occurred on ascent to each new altitude followed by a gradual decline during prolonged stay...
- Fibrothorax and severe lung restriction secondary to lupus pleuritis and its successful treatment by pleurectomySat Sharma
Section of Respirology, University of Manitoba, Winnipeg, Canada
Can Respir J 9:335-7. 2002..Medical therapy of systemic lupus erythematosus has been proven to be effective in controlling pleuritis in most cases. However, in the event of refractory pleuritis or pleural thickening, decortication may be a viable alternative...
- Is HRCT the best way to diagnose idiopathic interstitial fibrosis?Sat Sharma
University of Manitoba, St Boniface General Hospital, Winnipeg, Manitoba, Canada
Curr Opin Pulm Med 12:323-30. 2006..In diffuse lung diseases, HRCT now has a central role in routine diagnostic evaluation, and a major impact on the utility of other diagnostic tests, especially bronchoalveolar lavage and surgical lung biopsy...
- Secondary pulmonary arterial hypertension: treated with endothelin receptor blockadeSat Sharma
Section of Pulmonary and Critical Care Medicine, Department of Internal Medicine, University of Manitoba, Winnipeg, Manitoba, R2H 2A6, Canada
Tex Heart Inst J 32:405-10. 2005..This case series suggests a role for endothelin receptor blockade therapy in SPAH and should generate further interest in pharmacologic management of SPAH. A prospective controlled clinical trial of bosentan in SPAH is urgently needed...
- Septic shock, multiple organ failure, and acute respiratory distress syndromeSat Sharma
Section of Pulmonary Care Medicine, Department of Internal Medicine, University of Manitoba, Winnipeg, Manitoba, Canada
Curr Opin Pulm Med 9:199-209. 2003..This review will highlight and discuss recent advances in the pathophysiology and management of sepsis...
- Role of antimicrobial agents in the management of exacerbations of COPDSat Sharma
Section of Respirology, Department of Internal Medicine, University of Manitoba, Winnipeg, Manitoba, Canada
Treat Respir Med 4:153-67. 2005..An aggressive management approach in complicated exacerbations may reduce costs by reducing healthcare utilization and hospitalization...
- Practice patterns of respirologists in CanadaSat Sharma
Section of Respirology, Department of Internal Medicine, University of Manitoba, St Boniface General Hospital, BG034 409 Tache Avenue, Winnipeg, Manitoba R2H 2A6, Canada
Can Respir J 9:395-400. 2002..2%) and thoracoscopy (11.3%). Because 97% of pulmonary specialists would like to perform invasive procedures, fellowship programs, mini-residencies and practical courses should provide the necessary training...
- Antimicrobial management of sepsis and septic shockSat Sharma
Section of Pulmonary Medicine, Department of Internal Medicine, University of Manitoba, 700 William Avenue, Winnipeg, Manitoba, Canada R3E 0Z3
Clin Chest Med 29:677-87, ix. 2008..Antimicrobial therapy should be stopped if infection is not considered the etiologic factor for a shock state...
- The impact of repeated marathon running on cardiovascular function in the aging populationErin Karlstedt
Institute of Cardiovascular Sciences, St, Boniface Research Centre, University of Manitoba, Winnipeg, MB, Canada
J Cardiovasc Magn Reson 14:58. 2012..Whether or not permanent myocardial injury occurs due to repeated marathon running in the aging population remains controversial...
- Steroids and/or cytotoxic agents should be used early in the management of patients with IPF--the pro argumentSat Sharma
Section of Respirology, University of Manitoba, Winnipeg
Can Respir J 11:207-9. 2004
- Outcome of patients admitted to the intensive care unit for acute exacerbation of idiopathic pulmonary fibrosisFahad M Al-Hameed
Department of Internal Medicine, University of Manitoba, Winnipeg, Canada
Can Respir J 11:117-22. 2004..The aim of this study was to evaluate the outcome of intensive care unit (ICU) admission in patients with idiopathic pulmonary fibrosis (IPF) who develop acute respiratory failure of unknown etiology...
- Hepatic hydrothorax -- how would you manage it?Hassan Al-sharif
University of Manitoba, Winnipeg, Canada
Can Respir J 12:440-2. 2005..The pathophysiology of hepatic hydrothorax, the role of various therapeutic options and the current favoured therapy for this not so uncommon disorder are reviewed...
- Has mediastinoscopy still a role in suspected stage I sarcoidosis?Smita Sakha Pakhale
Sections of Pulmonary and Critical Care, Department of Internal Medicine, University of Manitoba, Winnipeg, MB, Canada
Sarcoidosis Vasc Diffuse Lung Dis 23:66-9. 2006..Whether diagnostic mediastinoscopy is needed for confirmation of diagnosis in patients who present with clinical stage I sarcoidosis and no lung lesions on CT scan, is not known...
- Relation of biomarkers and cardiac magnetic resonance imaging after marathon runningNegareh Mousavi
Section of Cardiology, Department of Cardiac Sciences, St Boniface Research Centre, University of Manitoba, Winnipeg, Manitoba, Canada
Am J Cardiol 103:1467-72. 2009..The increase in cardiac troponin after marathon running is likely due to the cytosolic release of the biomarker, not to the true breakdown of the myocyte, as confirmed by delayed enhancement CMR imaging...
- Pulmonary interstitial fibrosis as a presenting manifestation in perinuclear antineutrophilic cytoplasmic antibody microscopic polyangiitisGregg M Eschun
University of Manitoba, Winnipeg, Manitoba, Canada
Chest 123:297-301. 2003..Further appreciation of this finding may lead to more data with respect to the incidence of PIF in MPA, and to a better understanding of the mechanisms that are involved in the development of this finding...
- Treatment of pulmonary arterial hypertension: a step forwardSat Sharma
Chest 124:8-11. 2003
- Tiotropium in combination with placebo, salmeterol, or fluticasone-salmeterol for treatment of chronic obstructive pulmonary disease: a randomized trialShawn D Aaron
The Ottawa Health Research Institute and University of Ottawa, Ottawa, Ontario, Canada
Ann Intern Med 146:545-55. 2007..Treatment of moderate or severe chronic obstructive pulmonary disease (COPD) with combinations of inhaled corticosteroids, long-acting beta-agonists, and long-acting anticholinergic bronchodilators is common but unstudied...