Affiliation: University of Toronto
- Measuring the elastic modulus of ex vivo small tissue samplesAbbas Samani
Department of Medical Biophysics, University of Toronto, 2075 Bayview Avenue, Toronto, Ontario, M4N 3M5, Canada
Phys Med Biol 48:2183-98. 2003..The tissue Young's modulus is then reconstructed from the measured displacements using an inversion technique. Finally, preliminary elasticity measurement results of various breast tissues are presented and discussed...
- Elastic moduli of normal and pathological human breast tissues: an inversion-technique-based investigation of 169 samplesAbbas Samani
Department of Medical Biophysics Electrical and Computer Engineering, University of Western Ontario, Medical Sciences Building, London, Ontario, N6A 5C1, Canada
Phys Med Biol 52:1565-76. 2007..A statistical analysis showed that differences between the elastic modulus of the majority of those tissues were statistically significant. Implications for the specificity advantages of elastography are reviewed...
- Biomechanical 3-D finite element modeling of the human breast using MRI dataA Samani
Department of Medical Biophysics, Sunnybrook and Women s College Health Sciences Centre, University of Toronto, ON, Canada
IEEE Trans Med Imaging 20:271-9. 2001..The model was also applied to a breast image registration problem of a volunteer's breast. Although qualitatively reasonable, further work is required to validate the results quantitatively...
- A constrained modulus reconstruction technique for breast cancer assessmentA Samani
Department of Medical Biophysics, University of Toronto, ON, Canada
IEEE Trans Med Imaging 20:877-85. 2001..Breast tissue modulus reconstruction using simulated data and phantom modulus reconstruction using experimental data indicate that the technique is robust...
- Visualization and quantification of breast cancer biomechanical properties with magnetic resonance elastographyD B Plewes
Department of Medical Biophysics, Sunnybrook and Women s College Health Sciences Centre, Toronto, Ontario, Canada
Phys Med Biol 45:1591-610. 2000..An experimental apparatus for clinical breast MRE and preliminary images of a normal volunteer are presented...
- Measurement of the hyperelastic properties of ex vivo brain tissue slicesT Kaster
Department of Medical Biophysics, University of Western Ontario, London, Ontario, Canada
J Biomech 44:1158-63. 2011..Due to the significant differences between the linear and non-linear tissue response, we conclude that incorporating these differences into brain biomechanical models is necessary to increase accuracy...
- A method to measure the hyperelastic parameters of ex vivo breast tissue samplesAbbas Samani
Department of Medical Biophysics Electrical and Computer Engineering, University of Western Ontario, London, ON N6A 5C1, Canada
Phys Med Biol 49:4395-405. 2004..The features of the system are demonstrated with two samples of breast tissue and typical hyperelastic results are presented...
- Detecting mechanical abnormalities in prostate tissue using FE-based image registrationPatrick Courtis
Department of Electrical and Computer Engineering, University of Western Ontario
Med Image Comput Comput Assist Interv 10:244-51. 2007..Results from the phantom study showed that the technique could detect the increased stiffness of the simulated tumor with a reasonable accuracy...
- An inverse problem solution for measuring the elastic modulus of intact ex vivo breast tissue tumoursAbbas Samani
Department of Medical Biophysics Electrical and Computer Engineering, University of Western Ontario, London, Ontario, N6A 5C1, Canada
Phys Med Biol 52:1247-60. 2007..These results indicate that the proposed method is robust and highly accurate. Furthermore, they indicate that a benign lesion and malignant tumours are roughly five times and ten times stiffer than normal breast tissues respectively...
- Observation of nonlinear shear wave propagation using magnetic resonance elastographyIngolf Sack
Institute of Radiology, Charite University Medicine Berlin, Humboldt University Berlin, Berlin, Germany
Magn Reson Med 52:842-50. 2004..Using an estimate of the strain energy of the phantom, we were able to determine the nonlinear tissue properties...
- MR validation of soft tissue mimicing phantom deformation as modeled by nonlinear finite element analysisJustin Sciarretta
Department of Medical Biophysics, University of Toronto, North York, Ontario, Canada
Med Phys 29:65-72. 2002..A minimum difference was reached when the Poisson's ratio and coefficient of friction were set to 0.485 and 0.3, respectively. Under these conditions, the root mean square difference was found to be 14.4%...
- Towards a biomechanical-based method for assessing myocardial tissue viabilityCristian A Linte
Biomed Eng, Univ of Western Ontario, London, ON, Canada
Conf Proc IEEE Eng Med Biol Soc 1:2884-7. 2006..The result consists of a display-map of the contraction force distribution superimposed on the anatomical ventricle model, which allows the clinician to identify regions of low contractility in the myocardium...
- Towards a biomechanics-based technique for assessing myocardial contractility: an inverse problem approachCristian A Linte
Imaging Research Laboratories, Robarts Research Institute, London, Canada
Comput Methods Biomech Biomed Engin 11:243-55. 2008..Our next objective will consist of validating this technique by showing the correlation between the presence of low contraction force patterns and poor myocardial functionality...
- A "twisting and bending" model-based nonrigid image registration technique for 3-D ultrasound carotid imagesNuwan D Nanayakkara
Imaging Research Laboratories, Robarts Research Institute and Graduate Program in Biomedical Engineering, The University of Western Ontario, London, ON N6A5K8, Canada
IEEE Trans Med Imaging 27:1378-88. 2008..80 +/-0.26 mm using our nonrigid registration technique, which was a significant improvement in registration accuracy over rigid registration, even with reduced degrees-of-freedom compared to the other nonrigid registration algorithms...