W J Rushlow
Affiliation: University of Western Ontario
- Characterization of CArG-binding protein A initially identified by differential displayW J Rushlow
Department of Anatomy and Cell Biology, The University of Western Ontario and The London Health Sciences Centre, Canada
Neuroscience 94:637-49. 1999..The results of the current study leads us to suggest that CArG-binding protein A may be involved in brain development and the regulation of the serum response element...
- Changes in CArG-binding protein A expression levels following injection(s) of the D1-dopamine agonist SKF-82958 in the intact and 6-hydroxydopamine-lesioned ratW J Rushlow
Department of Anatomy and Cell Biology, The University of Western Ontario, Ontario, London, Canada
Neuroscience 98:69-78. 2000..The results demonstrate that CArG-binding protein A responds to SKF-82958 and that the changes in CArG-binding protein A match perfectly with the pattern of c-Fos induction induced by the D1 agonist...
- Antipsychotics affect multiple calcium calmodulin dependent proteinsW J Rushlow
Department of Psychiatry, London Health Sciences Centre University Campus, London, Ontario, Canada
Neuroscience 161:877-86. 2009..The results collectively suggest that antipsychotic specifically target several proteins associated with CaM signaling...
- L-type calcium channel blockade on haloperidol-induced c-Fos expression in the striatumJ Lee
Department of Anatomy and Cell Biology, University of Western Ontario, London, Ontario N6A 5C1, Canada
Neuroscience 149:602-16. 2007..Collectively, the results suggest that coadministration of L-type Ca(2+) channel blockers affects haloperidol signaling in the lateral part of the neostriatum and may exacerbate the development of acute motor side effects...
- The effects of neuropsychiatric drugs on glycogen synthase kinase-3 signalingL P Sutton
Department of Anatomy and Cell Biology, University of Western Ontario and the London Health Sciences Centre, London, ON, Canada
Neuroscience 199:116-24. 2011..In conclusion, regulation of the Wnt pathway is specific to antipsychotics, whereas antipsychotics, mood stabilizers, and antidepressants all affect Akt...
- The effects of antipsychotics on beta-catenin, glycogen synthase kinase-3 and dishevelled in the ventral midbrain of ratsH Alimohamad
Department of Anatomy and Cell Biology, The University of Western Ontario and The London Health Sciences Centre, London, Ontario, Canada
J Neurochem 95:513-25. 2005..Collectively, the results suggest that antipsychotics may exert their beneficial effects through modifications to proteins that are associated with the canonical Wnt pathway...
- Chronic hyperdopaminergic activity of schizophrenia is associated with increased ΔFosB levels and cdk-5 signaling in the nucleus accumbensR Cantrup
Department of Anatomy and Cell Biology, Schulich School of Medicine and Dentistry, Western University, London, ON, Canada
Neuroscience 222:124-35. 2012..Our results indicate that chronic hyperdopaminergic activity, as seen in schizophrenia, may affect glutamate and dopamine function in the NA via ΔFosB-mediated transcriptional modulation...
- Changes in calcineurin expression induced in the rat brain by the administration of antipsychoticsW J Rushlow
Department of Psychiatry, the University of Western Ontario and the London Health Sciences Centres, London, Ontario, Canada
J Neurochem 94:587-96. 2005..Collectively the results suggest that CN may be a common target for antipsychotics and that antipsychotic-induced alterations in CN may represent one of the mechanisms by which antipsychotics alleviate psychosis...
- Differential gene expression in premalignant human trophoblast: role of IGFBP-5B P Lee
Department of Anatomy and Cell Biology, University of Western Ontario, London, Ontario, Canada
Int J Cancer 94:674-84. 2001..The functions of the other differentially expressed genes, some of which are essential for cell cycle progression or cell survival require further investigation...