Gregor S D Reid

Summary

Affiliation: University of British Columbia
Country: Canada

Publications

  1. ncbi CpG stimulation of precursor B-lineage acute lymphoblastic leukemia induces a distinct change in costimulatory molecule expression and shifts allogeneic T cells toward a Th1 response
    Gregor S D Reid
    Room 217, BCRI, 950 W 28th Ave, Vancouver, BC V5Z 4H4, Canada
    Blood 105:3641-7. 2005
  2. ncbi Differential immune effects mediated by Toll-like receptors stimulation in precursor B-cell acute lymphoblastic leukaemia
    Sophie L Corthals
    Division of Haematology, Oncology, Bone Marrow Transplantation, Department of Pediatrics, University of British Columbia and British Columbia s Children s Hospital, Vancouver, BC, Canada
    Br J Haematol 132:452-8. 2006
  3. ncbi In vivo control of acute lymphoblastic leukemia by immunostimulatory CpG oligonucleotides
    Hisaki Fujii
    Department of Pediatrics, Division of Hematology Oncology Bone Marrow Transplantation, University of British Columbia and British Columbia s Children s Hospital, Vancouver, Canada
    Blood 109:2008-13. 2007
  4. ncbi The cationic antimicrobial peptide LL-37 modulates dendritic cell differentiation and dendritic cell-induced T cell polarization
    Donald J Davidson
    British Columbia Research Institute for Child and Family Health, Room 381, 950 West 28th Avenue, Vancouver, British Columbia, Canada V5Z 4H4
    J Immunol 172:1146-56. 2004
  5. ncbi Progression of spontaneous autoimmune diabetes is associated with a switch in the killing mechanism used by autoreactive CTL
    Huilian Qin
    Department of Pathology and Laboratory Medicine, University of British Columbia, BC s Children s Hospital, 4480 Oak Street, Vancouver, British Columbia, V6H 3VA, Canada
    Int Immunol 16:1657-62. 2004
  6. ncbi Immune evasion strategies of pediatric precursor-B acute lymphoblastic leukemia after allogeneic bone marrow transplantation-a case study
    Draga Barbaric
    Department of Pediatrics, Division of Hematology Oncology Bone Marrow Transplantation, University of British Columbia and British Columbia s Children s Hospital, Vancouver, BC, Canada
    Leuk Res 29:711-4. 2005
  7. ncbi ETV6 (TEL)-AML1 pre-B acute lymphoblastic leukaemia cells are associated with a distinct antigen-presenting phenotype
    Angela J Alessandri
    Department of Pediatrics, Division of Hematology Oncology Bone Marrow Transplantation, University of British Columbia and British Columbia s Children s Hospital, Vancouver, BC, Canada
    Br J Haematol 116:266-72. 2002
  8. pmc mTOR inhibitors are synergistic with methotrexate: an effective combination to treat acute lymphoblastic leukemia
    David T Teachey
    Division of Oncology, Department of Pediatrics, Children s Hospital of Philadelphia, PA 19104, USA
    Blood 112:2020-3. 2008
  9. ncbi Primary immunodeficiency to pneumococcal infection due to a defect in Toll-like receptor signaling
    Andrew J Currie
    Division of Infectious and Immunological Diseases, British Columbia s Research Institute for Child and Family Health, 950 West 28th Avenue, Vancouver, British Columbia, Canada V5Z 4H4
    J Pediatr 144:512-8. 2004
  10. ncbi Altered patterns of T cell cytokine production induced by relapsed pre-B ALL cells
    Gregor S D Reid
    Department of Pediatrics, University of British Columbia and B C s Children s Hospital, 4480 Oak Street, BC V5Z 4H4 Vancouver, Canada
    Leuk Res 27:1135-42. 2003

Collaborators

Detail Information

Publications11

  1. ncbi CpG stimulation of precursor B-lineage acute lymphoblastic leukemia induces a distinct change in costimulatory molecule expression and shifts allogeneic T cells toward a Th1 response
    Gregor S D Reid
    Room 217, BCRI, 950 W 28th Ave, Vancouver, BC V5Z 4H4, Canada
    Blood 105:3641-7. 2005
    ..These results demonstrate the functional relevance of CpG stimulation of precursor B-ALL cells and provide a rational basis for study of these agents for use in treatment of this disease...
  2. ncbi Differential immune effects mediated by Toll-like receptors stimulation in precursor B-cell acute lymphoblastic leukaemia
    Sophie L Corthals
    Division of Haematology, Oncology, Bone Marrow Transplantation, Department of Pediatrics, University of British Columbia and British Columbia s Children s Hospital, Vancouver, BC, Canada
    Br J Haematol 132:452-8. 2006
    ..These results suggest that TLR ligands, in addition to TLR9 agonists, may provide a strategy to enhance the generation of anti-ALL immune activity by skewing responding T cells towards a Th1 response...
  3. ncbi In vivo control of acute lymphoblastic leukemia by immunostimulatory CpG oligonucleotides
    Hisaki Fujii
    Department of Pediatrics, Division of Hematology Oncology Bone Marrow Transplantation, University of British Columbia and British Columbia s Children s Hospital, Vancouver, Canada
    Blood 109:2008-13. 2007
    ..These results suggest that CpG ODNs have potential as therapeutic agents for the treatment of ALL...
  4. ncbi The cationic antimicrobial peptide LL-37 modulates dendritic cell differentiation and dendritic cell-induced T cell polarization
    Donald J Davidson
    British Columbia Research Institute for Child and Family Health, Room 381, 950 West 28th Avenue, Vancouver, British Columbia, Canada V5Z 4H4
    J Immunol 172:1146-56. 2004
    ..LL-37 may be an attractive therapeutic candidate for manipulating T cell polarization by DC...
  5. ncbi Progression of spontaneous autoimmune diabetes is associated with a switch in the killing mechanism used by autoreactive CTL
    Huilian Qin
    Department of Pathology and Laboratory Medicine, University of British Columbia, BC s Children s Hospital, 4480 Oak Street, Vancouver, British Columbia, V6H 3VA, Canada
    Int Immunol 16:1657-62. 2004
    ..These results provide direct evidence for age-related changes in the cytotoxic pathways used by diabetogenic T cells during the progression of autoimmune diabetes...
  6. ncbi Immune evasion strategies of pediatric precursor-B acute lymphoblastic leukemia after allogeneic bone marrow transplantation-a case study
    Draga Barbaric
    Department of Pediatrics, Division of Hematology Oncology Bone Marrow Transplantation, University of British Columbia and British Columbia s Children s Hospital, Vancouver, BC, Canada
    Leuk Res 29:711-4. 2005
    ..This study suggests that escape from immune mechanisms after withdrawal of immune suppression is important to ALL progression...
  7. ncbi ETV6 (TEL)-AML1 pre-B acute lymphoblastic leukaemia cells are associated with a distinct antigen-presenting phenotype
    Angela J Alessandri
    Department of Pediatrics, Division of Hematology Oncology Bone Marrow Transplantation, University of British Columbia and British Columbia s Children s Hospital, Vancouver, BC, Canada
    Br J Haematol 116:266-72. 2002
    ..In the case of ETV6-AML1 pre-B ALL, this characteristic immunophenotype may have implications for the immunogenicity of the leukaemic cells...
  8. pmc mTOR inhibitors are synergistic with methotrexate: an effective combination to treat acute lymphoblastic leukemia
    David T Teachey
    Division of Oncology, Department of Pediatrics, Children s Hospital of Philadelphia, PA 19104, USA
    Blood 112:2020-3. 2008
    ..We found methotrexate and MTIs are an effective and potentially synergistic combination in ALL...
  9. ncbi Primary immunodeficiency to pneumococcal infection due to a defect in Toll-like receptor signaling
    Andrew J Currie
    Division of Infectious and Immunological Diseases, British Columbia s Research Institute for Child and Family Health, 950 West 28th Avenue, Vancouver, British Columbia, Canada V5Z 4H4
    J Pediatr 144:512-8. 2004
    ..We investigated the role of TLR signaling in defense against infection in a 3-year-old boy with a severe defect resulting in recurrent Streptococcus pneumoniae bacteremia...
  10. ncbi Altered patterns of T cell cytokine production induced by relapsed pre-B ALL cells
    Gregor S D Reid
    Department of Pediatrics, University of British Columbia and B C s Children s Hospital, 4480 Oak Street, BC V5Z 4H4 Vancouver, Canada
    Leuk Res 27:1135-42. 2003
    ....
  11. doi Detection of WT1-specific T cells in paediatric acute lymphoblastic leukaemia patients in first remission
    Draga Barbaric
    Br J Haematol 141:271-3. 2008