Richard L O'Reilly

Summary

Affiliation: University of Western Ontario
Country: Canada

Publications

  1. pmc Olanzapine-induced methylation alters cadherin gene families and associated pathways implicated in psychosis
    Melkaye G Melka
    Molecular Genetics Unit, Department of Biology, The University of Western Ontario, London, ON N6A 5B7, Canada
    BMC Neurosci 15:112. 2014
  2. pmc Monozygotic twins with early-onset schizophrenia and late-onset bipolar disorder: a case report
    Richard O'reilly
    Department of Psychiatry, University of Western Ontario, St, Joseph s Regional Mental Health Care, 850 Highbury Avenue North, London, ON, N6A 4H1, Canada
    J Med Case Rep 7:134. 2013
  3. pmc DNA methylation and mRNA expression of SYN III, a candidate gene for schizophrenia
    Brenda C Murphy
    Molecular Genetics Unit, Department of Biology and Division of Medical Genetics, The University of Western Ontario, London, Ontario N6A 5B7, Canada
    BMC Med Genet 9:115. 2008
  4. ncbi request reprint Why are community treatment orders controversial?
    Richard O'reilly
    Department of Psychiatry, The University of Western Ontario, London
    Can J Psychiatry 49:579-84. 2004
  5. ncbi request reprint A qualitative analysis of the use of community treatment orders in Saskatchewan
    Richard L O'Reilly
    Department of Psychiatry, The University of Western Ontario, Canada
    Int J Law Psychiatry 29:516-24. 2006
  6. doi request reprint The capacity to execute an advance directive for psychiatric treatment
    Richard L O'Reilly
    The University of Western Ontario, Research and Education Unit, Regional Mental Health Care, London St Thomas, ON, Canada
    Int J Law Psychiatry 31:66-71. 2008
  7. ncbi request reprint Treatment delays for involuntary psychiatric patients associated with reviews of treatment capacity
    Michelle Kelly
    Research and Education Unit, Regional Mental Health Care, St Joseph s Health Care, London, Ontario
    Can J Psychiatry 47:181-5. 2002
  8. ncbi request reprint Site-specific cytosine methylation in S-COMT promoter in 31 brain regions with implications for studies involving schizophrenia
    Brenda C Murphy
    Molecular Genetics Unit, Department of Biology and Division of Medical Genetics, The University of Western Ontario, London, Ontario, Canada
    Am J Med Genet B Neuropsychiatr Genet 133:37-42. 2005
  9. pmc DNA methylation differences in monozygotic twin pairs discordant for schizophrenia identifies psychosis related genes and networks
    Christina A Castellani
    Department of Biology, The University of Western Ontario, N6A 5B7, London, Ontario, Canada
    BMC Med Genomics 8:17. 2015
  10. pmc Biological relevance of CNV calling methods using familial relatedness including monozygotic twins
    Christina A Castellani
    Department of Biology, The University of Western Ontario, London N6A 5B7, ON, Canada
    BMC Bioinformatics 15:114. 2014

Collaborators

Detail Information

Publications14

  1. pmc Olanzapine-induced methylation alters cadherin gene families and associated pathways implicated in psychosis
    Melkaye G Melka
    Molecular Genetics Unit, Department of Biology, The University of Western Ontario, London, ON N6A 5B7, Canada
    BMC Neurosci 15:112. 2014
    ..A number of these molecules have been implicated in the causation of schizophrenia and related disorders...
  2. pmc Monozygotic twins with early-onset schizophrenia and late-onset bipolar disorder: a case report
    Richard O'reilly
    Department of Psychiatry, University of Western Ontario, St, Joseph s Regional Mental Health Care, 850 Highbury Avenue North, London, ON, N6A 4H1, Canada
    J Med Case Rep 7:134. 2013
    ..Schizophrenia and bipolar disorder are generally considered to be distinct illnesses. One piece of evidence supporting their distinctness is the rarity of schizophrenia and bipolar disorder occurring in monozygotic co‒twins...
  3. pmc DNA methylation and mRNA expression of SYN III, a candidate gene for schizophrenia
    Brenda C Murphy
    Molecular Genetics Unit, Department of Biology and Division of Medical Genetics, The University of Western Ontario, London, Ontario N6A 5B7, Canada
    BMC Med Genet 9:115. 2008
    ..The synapsin III (SYN III) gene on chromosome 22q is a candidate gene for schizophrenia susceptibility due to its chromosome location, neurological function, expression patterns and functional polymorphisms...
  4. ncbi request reprint Why are community treatment orders controversial?
    Richard O'reilly
    Department of Psychiatry, The University of Western Ontario, London
    Can J Psychiatry 49:579-84. 2004
    ..This paper describes the major sources of contention, outlines the position of the protagonists, and where possible, attempts to answer some of the questions raised and identify common ground...
  5. ncbi request reprint A qualitative analysis of the use of community treatment orders in Saskatchewan
    Richard L O'Reilly
    Department of Psychiatry, The University of Western Ontario, Canada
    Int J Law Psychiatry 29:516-24. 2006
    ..Family members viewed CTOs as necessary to control a chaotic situation caused by the subject's limited insight...
  6. doi request reprint The capacity to execute an advance directive for psychiatric treatment
    Richard L O'Reilly
    The University of Western Ontario, Research and Education Unit, Regional Mental Health Care, London St Thomas, ON, Canada
    Int J Law Psychiatry 31:66-71. 2008
    ....
  7. ncbi request reprint Treatment delays for involuntary psychiatric patients associated with reviews of treatment capacity
    Michelle Kelly
    Research and Education Unit, Regional Mental Health Care, St Joseph s Health Care, London, Ontario
    Can J Psychiatry 47:181-5. 2002
    ....
  8. ncbi request reprint Site-specific cytosine methylation in S-COMT promoter in 31 brain regions with implications for studies involving schizophrenia
    Brenda C Murphy
    Molecular Genetics Unit, Department of Biology and Division of Medical Genetics, The University of Western Ontario, London, Ontario, Canada
    Am J Med Genet B Neuropsychiatr Genet 133:37-42. 2005
    ..The unique observation of a completely methylated cytosine 23 in one patient with SZ may have the potential to affect COMT mRNA transcription and gene activity, but remains to be evaluated...
  9. pmc DNA methylation differences in monozygotic twin pairs discordant for schizophrenia identifies psychosis related genes and networks
    Christina A Castellani
    Department of Biology, The University of Western Ontario, N6A 5B7, London, Ontario, Canada
    BMC Med Genomics 8:17. 2015
    ..This high discordance is often explained by the role of yet unknown environmental, random, and epigenetic factors. The involvement of DNA methylation in this disease appears logical, but remains to be established...
  10. pmc Biological relevance of CNV calling methods using familial relatedness including monozygotic twins
    Christina A Castellani
    Department of Biology, The University of Western Ontario, London N6A 5B7, ON, Canada
    BMC Bioinformatics 15:114. 2014
    ..It has, therefore, become necessary to develop experimental protocols to test the reliability of CNV calling methods from microarray data so that researchers can properly discriminate biologically relevant data from noise...
  11. doi request reprint DNA methylation in psychosis: insights into etiology and treatment
    Christina A Castellani
    Department of Biology, The University of Western Ontario, London, Ontario, Canada
    Epigenomics 7:67-74. 2015
    ..The common cause is hypothesized to be aberrations resulting from medication use. However, this needs to be established by future studies that address the origin of methylation changes in psychosis. ..
  12. doi request reprint Copy number variation distribution in six monozygotic twin pairs discordant for schizophrenia
    Christina A Castellani
    Department of Biology, The University of Western Ontario, London, Ontario, Canada
    Twin Res Hum Genet 17:108-20. 2014
    ..An explanation for these differences is ontogenetic de novo events that differentiate in the monozygotic twins during development. ..
  13. ncbi request reprint Molecular characterization of a 2.7-kb, 12q13-specific, retroviral-related sequence isolated by RDA from monozygotic twin pairs discordant for schizophrenia
    Paromita Deb-Rinker
    Department of Zoology and Division of Medical Genetics, The University of Western Ontario, London, Canada
    Genome 45:381-90. 2002
    ....
  14. doi request reprint Supreme court of Canada's "Beautiful Mind" case
    John E Gray
    University of Western Ontario, Canada
    Int J Law Psychiatry 32:315-22. 2009
    ..We conclude that a law that allows a person with a mental illness to be incarcerated indefinitely in a "hospital" because needed psychiatric treatment cannot, by law, be provided is not justifiable in a caring democratic jurisdiction...