Anne Monique Nuyt

Summary

Affiliation: University of Montreal
Country: Canada

Publications

  1. doi Transient neonatal high oxygen exposure leads to early adult cardiac dysfunction, remodeling, and activation of the renin-angiotensin system
    Mariane Bertagnolli
    Division of Neonatology, Department of Pediatrics, Sainte Justine University Hospital Research Center, 3175, Chemin de la Cote Sainte Catherine, H3T 1C5, Montreal, Quebec, Canada
    Hypertension 63:143-50. 2014
  2. pmc Developmental programming and hypertension
    Anne Monique Nuyt
    Department of Pediatrics, Research Center, CHU Sainte Justine, Universite de Montreal, Canada
    Curr Opin Nephrol Hypertens 18:144-52. 2009
  3. doi Neonatal oxygen exposure in rats leads to cardiovascular and renal alterations in adulthood
    Catherine Yzydorczyk
    Department of Pediatrics, Research Center, CHU Sainte Justine, Universite de Montreal, Montreal, Quebec, Canada
    Hypertension 52:889-95. 2008
  4. doi Maternal and fetal leptin, adiponectin levels and associations with fetal insulin sensitivity
    Zhong Cheng Luo
    Department of Obstetrics and Gynecology, CHU Sainte Justine, University of Montreal, Montreal, Quebec, Canada
    Obesity (Silver Spring) 21:210-6. 2013
  5. doi Neonatal exposure to oxidants induces later in life a metabolic response associated to a phenotype of energy deficiency in an animal model of total parenteral nutrition
    Niina Kleiber
    Department of Pediatrics, CHU Sainte Justine, University of Montreal, 3175 Chemin de la Côte Ste Catherine, Montreal, Quebec, Canada
    Pediatr Res 68:188-92. 2010
  6. doi Developmental programming of eNOS uncoupling and enhanced vascular oxidative stress in adult rats after transient neonatal oxygen exposure
    Catherine Yzydorczyk
    Sainte Justine University Hospital and Research Center, Department of Pediatrics, Universite de Montreal, Montreal, Quebec, Canada
    J Cardiovasc Pharmacol 61:8-16. 2013
  7. pmc Remodeling of aorta extracellular matrix as a result of transient high oxygen exposure in newborn rats: implication for arterial rigidity and hypertension risk
    Fanny Huyard
    Sainte Justine University Hospital Research Center, Department of Paediatrics, Universite de Montreal, Montreal, Quebec, Canada
    PLoS ONE 9:e92287. 2014
  8. doi Maternal plasma 25-hydroxyvitamin D levels, angiogenic factors, and preeclampsia
    Shu Qin Wei
    Department of Obstetrics and Gynecology, Sainte Justine Hospital, University of Montreal, Montreal, QC, Canada
    Am J Obstet Gynecol 208:390.e1-6. 2013
  9. ncbi Antenatal antioxidant prevents adult hypertension, vascular dysfunction, and microvascular rarefaction associated with in utero exposure to a low-protein diet
    Gilles Cambonie
    Research Center, Hopital Sainte Justine, Department of Pediatrics, University of Montreal, 3175 Cote Sainte Catherine, Montreal, Quebec, Canada, H3T 1C5
    Am J Physiol Regul Integr Comp Physiol 292:R1236-45. 2007
  10. doi Risk for preterm and very preterm delivery in women who were born preterm
    Ariane Boivin
    Departments of Paediatrics, Obstetrics and Gynaecology, and Social and Preventive Medicine, Sainte Justine University Hospital and Research Center, University of Montreal, Montreal, and the School of Psychology, Laval University, Quebec City, Quebec, Canada
    Obstet Gynecol 125:1177-84. 2015

Collaborators

Detail Information

Publications28

  1. doi Transient neonatal high oxygen exposure leads to early adult cardiac dysfunction, remodeling, and activation of the renin-angiotensin system
    Mariane Bertagnolli
    Division of Neonatology, Department of Pediatrics, Sainte Justine University Hospital Research Center, 3175, Chemin de la Cote Sainte Catherine, H3T 1C5, Montreal, Quebec, Canada
    Hypertension 63:143-50. 2014
    ..These results are relevant to the growing population of individuals born preterm who may be at higher risk of cardiac dysfunction when faced with increased peripheral resistance associated with hypertension, vascular diseases, and aging...
  2. pmc Developmental programming and hypertension
    Anne Monique Nuyt
    Department of Pediatrics, Research Center, CHU Sainte Justine, Universite de Montreal, Canada
    Curr Opin Nephrol Hypertens 18:144-52. 2009
    ..This review will focus on advances in our comprehension of developmental programming of hypertension...
  3. doi Neonatal oxygen exposure in rats leads to cardiovascular and renal alterations in adulthood
    Catherine Yzydorczyk
    Department of Pediatrics, Research Center, CHU Sainte Justine, Universite de Montreal, Montreal, Quebec, Canada
    Hypertension 52:889-95. 2008
    ..Our findings support the hypothesis of developmental programming of adult cardiovascular and renal diseases and provide new insights into the potential role of oxidative stress in this process...
  4. doi Maternal and fetal leptin, adiponectin levels and associations with fetal insulin sensitivity
    Zhong Cheng Luo
    Department of Obstetrics and Gynecology, CHU Sainte Justine, University of Montreal, Montreal, Quebec, Canada
    Obesity (Silver Spring) 21:210-6. 2013
    ..It remains uncertain whether leptin and adiponectin levels are correlated in maternal vs. fetal circulations. Little is known about whether leptin and adiponectin affect insulin sensitivity during fetal life...
  5. doi Neonatal exposure to oxidants induces later in life a metabolic response associated to a phenotype of energy deficiency in an animal model of total parenteral nutrition
    Niina Kleiber
    Department of Pediatrics, CHU Sainte Justine, University of Montreal, 3175 Chemin de la Côte Ste Catherine, Montreal, Quebec, Canada
    Pediatr Res 68:188-92. 2010
    ..In conclusion, neonatal exposure to oxidant molecules such as peroxides has important consequences later in life on lipid and glucose metabolism leading to a phenotype of energy deficiency...
  6. doi Developmental programming of eNOS uncoupling and enhanced vascular oxidative stress in adult rats after transient neonatal oxygen exposure
    Catherine Yzydorczyk
    Sainte Justine University Hospital and Research Center, Department of Pediatrics, Universite de Montreal, Montreal, Quebec, Canada
    J Cardiovasc Pharmacol 61:8-16. 2013
    ....
  7. pmc Remodeling of aorta extracellular matrix as a result of transient high oxygen exposure in newborn rats: implication for arterial rigidity and hypertension risk
    Fanny Huyard
    Sainte Justine University Hospital Research Center, Department of Paediatrics, Universite de Montreal, Montreal, Quebec, Canada
    PLoS ONE 9:e92287. 2014
    ..Importantly, these changes are present prior to the elevation of blood pressure and vascular dysfunction in this model, and may therefore be contributory. ..
  8. doi Maternal plasma 25-hydroxyvitamin D levels, angiogenic factors, and preeclampsia
    Shu Qin Wei
    Department of Obstetrics and Gynecology, Sainte Justine Hospital, University of Montreal, Montreal, QC, Canada
    Am J Obstet Gynecol 208:390.e1-6. 2013
    ....
  9. ncbi Antenatal antioxidant prevents adult hypertension, vascular dysfunction, and microvascular rarefaction associated with in utero exposure to a low-protein diet
    Gilles Cambonie
    Research Center, Hopital Sainte Justine, Department of Pediatrics, University of Montreal, 3175 Cote Sainte Catherine, Montreal, Quebec, Canada, H3T 1C5
    Am J Physiol Regul Integr Comp Physiol 292:R1236-45. 2007
    ..These studies support the concept that perinatal oxidative insult can lead to permanent alterations in the cardiovascular system development...
  10. doi Risk for preterm and very preterm delivery in women who were born preterm
    Ariane Boivin
    Departments of Paediatrics, Obstetrics and Gynaecology, and Social and Preventive Medicine, Sainte Justine University Hospital and Research Center, University of Montreal, Montreal, and the School of Psychology, Laval University, Quebec City, Quebec, Canada
    Obstet Gynecol 125:1177-84. 2015
    ..To evaluate whether women who themselves were born preterm are at increased risk of preterm delivery and, if so, whether known maternal complications of preterm birth such as hypertension or diabetes explain this risk...
  11. doi Endostatin levels and the risk of subsequent preeclampsia
    Sarah Thissier-Levy
    Department of Obstetrics and Gynecology, CHU Sainte Justine Research Center, Universite de Montreal, 3175 Cote Ste Catherine, Montreal, Quebec H3T 1C5, Canada
    Eur J Obstet Gynecol Reprod Biol 170:396-400. 2013
    ..To evaluate endostatin, an anti-angiogenic factor, in relation to the risk of preeclampsia (PE)...
  12. doi Maternal and fetal IGF-I and IGF-II levels, fetal growth, and gestational diabetes
    Zhong Cheng Luo
    Department of Obstetrics and Gynecology, Centre hospitalier universitaire Sainte Justine, University of Montreal, 3175 Cote Sainte Catherine, Montreal, Canada H3T 1C5
    J Clin Endocrinol Metab 97:1720-8. 2012
    ..It remains uncertain whether maternal IGF-I is associated with fetal growth. Little is known about the role of maternal IGF-II in fetal growth and whether IGF-I or IGF-II is implicated in fetal hypertrophy in gestational diabetes...
  13. pmc Circulating docosahexaenoic acid levels are associated with fetal insulin sensitivity
    Jin ping Zhao
    Department of Obstetrics and Gynecology, University of Montreal, Montreal, Quebec, Canada
    PLoS ONE 9:e85054. 2014
    ....
  14. ncbi Mechanisms underlying developmental programming of elevated blood pressure and vascular dysfunction: evidence from human studies and experimental animal models
    Anne Monique Nuyt
    Department of Pediatrics, CHU Sainte Justine Research Center, Universite de Montreal, 3175 Cote Sainte Catherine, Montreal, Quebec, Canada
    Clin Sci (Lond) 114:1-17. 2008
    ....
  15. doi Comparing Carotid and Brachial Artery Stiffness: A First Step Toward Mechanical Mapping of the Arterial Tree
    Roch L Maurice
    Service de cardiologie, Centre Hospitalier Universitaire Sainte Justine CHUSJ, Universite de Montreal, Montreal, Canada Centre de recherche, Centre Hospitalier Universitaire Sainte Justine CRCHUSJ, Universite de Montreal, Montreal, Canada Electronic address
    Ultrasound Med Biol 41:1808-13. 2015
    ..The results reported here can be seen as the first step toward mechanical mapping of the arterial tree. ..
  16. doi Activation of the Cardiac Renin-Angiotensin System in High Oxygen-Exposed Newborn Rats: Angiotensin Receptor Blockade Prevents the Developmental Programming of Cardiac Dysfunction
    Mariane Bertagnolli
    From the Department of Pediatrics, Sainte Justine University Hospital Research Center, Faculty of Medicine, Universite de Montreal, Montreal, Quebec, Canada M B, A D, S B B, G G, M S, M A L, A C, A M N and Lady Davis Institute for Medical Research, Jewish General Hospital, Department of Medicine, McGill University, Montreal, Quebec, Canada P P, E L S
    Hypertension 67:774-82. 2016
    ..These findings highlight the key role of neonatal renin-angiotensin system activation in the developmental programming of cardiac dysfunction induced by deleterious neonatal conditions. ..
  17. pmc Hyperoxia exposure impairs nephrogenesis in the neonatal rat: role of HIF-1α
    Constantin R Popescu
    Sainte Justine University Hospital and Research Center, and the Department of Pediatrics, Universite de Montreal, Montreal, Quebec, Canada
    PLoS ONE 8:e82421. 2013
    ..Overall, this study supports the premise that prematurely born neonates exposed to high oxygen levels after birth are vulnerable to impaired renal development...
  18. pmc Pregnancy complications among women born preterm
    Ariane Boivin
    Department of Paediatrics, University ofMontreal, Montreal, Quebec, Canada
    CMAJ 184:1777-84. 2012
    ..Low birth weight can result from intrauterine growth restriction, preterm birth or both. We examined the relation between preterm birth and pregnancy complications later in life...
  19. doi New reference curves for head circumference at birth, by gestational age
    Alexandre Barbier
    Departments of aPediatrics Neonatology, Sainte Justine University Hospital and Research Centre, University of Montreal, Quebec, Canada
    Pediatrics 131:e1158-67. 2013
    ..HC charts currently used in Canada are either dated, mixed-gender, nonrepresentative of lower gestational ages (GAs), or reflective of other populations...
  20. doi Long-term impact of an antioxidant-deficient neonatal diet on lipid and glucose metabolism
    Valérie Turcot
    Department of Nutrition, CHU Sainte Justine, Faculty of Medicine, University of Montreal, Montreal, QC, Canada H3T 1C5
    Free Radic Biol Med 47:275-82. 2009
    ..These findings suggest being aware of negative consequences when adopting "aggressive" antioxidant therapies in newborn infants...
  21. doi Acceptability and feasibility of a breast milk expression education and support intervention in mothers of preterm infants
    Marjolaine Héon
    Faculte des sciences infirmieres, Universite de Montreal, Quebec, Canada Drs Héon and Goulet Quebec Nursing Intervention Research Network, Montreal, Canada Dr Héon Faculté de biologie et de médecine, Universite de Lausanne, Switzerland Dr Goulet Research Centre, CHU Sainte Justine, Montreal, Quebec, Canada Ms Garofalo and Drs Nuyt and Levy Department of Nutrition, Universite de Montreal, Quebec, Canada Ms Garofalo and Dr Levy Department of Pediatrics, Universite de Montreal, Quebec, Canada Dr Nuyt
    Adv Neonatal Care 14:E9-E19. 2014
    ..A pilot study was conducted to assess the acceptability and feasibility of a breast milk expression education and support intervention in mothers of preterm infants and study procedures...
  22. pmc Maternal glucose tolerance in pregnancy affects fetal insulin sensitivity
    Zhong Cheng Luo
    Department of Obstetrics and Gynecology, CHU Sainte Justine, University of Montreal, Montreal, Quebec, Canada
    Diabetes Care 33:2055-61. 2010
    ..Offspring of mothers with impaired glucose tolerance are far more likely to develop type 2 diabetes. We tested the hypothesis that maternal glucose tolerance in pregnancy affects fetal insulin sensitivity or beta-cell function...
  23. doi Preterm Birth and Hypertension: Is There a Link?
    Mariane Bertagnolli
    Department of Pediatrics, Sainte Justine University Hospital Research Center, Universite de Montreal, 3175 chemin de la Cote Sainte Catherine, Montreal, Quebec, H3T 1C5, Canada
    Curr Hypertens Rep 18:28. 2016
    ..In this review, we will highlight evidence of developmental cardiovascular alterations and potential mechanisms linking preterm birth to the risk of hypertension and cardiovascular diseases into adulthood. ..
  24. doi Carotid wall elastography to assess midterm vascular dysfunction secondary to intrauterine growth restriction: feasibility and comparison with standardized intima-media thickness
    Roch L Maurice
    Service de cardiologie, Centre Hospitalier Universitaire Sainte Justine CHUSJ, Universite de Montreal, Montreal, Canada Centre de recherche, Centre Hospitalier Universitaire Sainte Justine CRCHUSJ, Universite de Montreal, Montreal, Canada Centre de recherche, Centre hospitalier de l Université de Montréal CRCHUM, Universite de Montreal, Montreal, Canada Université de Lyon, CREATIS CNRS UMR5220 INSERM U1044 INSA Lyon Université Lyon 1, France Electronic address
    Ultrasound Med Biol 40:864-70. 2014
    ..As early detection of vascular modulation is essential to early intervention in a population at risk, we now intend to extend ImBioMark to investigate larger pathologic cohorts with various degrees of arteriopathy...
  25. doi Early docosahexaenoic acid supplementation of mothers during lactation leads to high plasma concentrations in very preterm infants
    Isabelle Marc
    Departement de Pediatrie, Centre Hosipitalier de l Université Laval, Quebec, Canada
    J Nutr 141:231-6. 2011
    ..001). Early supplementation with DHA to lactating mothers with low dietary DHA intake successfully increased the plasma DHA status in very preterm infants...
  26. pmc Mechanisms of developmental programming of the metabolic syndrome and related disorders
    Zhong Cheng Luo
    Zhong Cheng Luo, Lin Xiao, Department of Obstetrics and Gynecology, CHU Sainte Justine, University of Montreal, Quebec H3T 1C5, Canada
    World J Diabetes 1:89-98. 2010
    ..A better understanding of the programming mechanisms is a prerequisite for developing early life interventions to arrest the increasing epidemic of the metabolic syndrome, type 2 diabetes and other related disorders...
  27. ncbi Role of brain and peripheral angiotensin II in hypertension and altered arterial baroreflex programmed during fetal life in rat
    Patrick Pladys
    Research Center, Hopital Sainte Justine, Department of Pediatrics, University of Montreal, 3175 Cote Sainte Catherine, Montreal, Quebec, Canada, H3T 1C5
    Pediatr Res 55:1042-9. 2004
    ..These data demonstrate a major tonic role of brain and peripheral RAS on hypertension associated with antenatal nutrient deprivation...
  28. ncbi Altered vascular function in fetal programming of hypertension
    Delphine Lamireau
    Research Center, Hopital Sainte Justine, Department of Pediatrics and Pharmacology, Universite de Montreal, Montreal, Canada
    Stroke 33:2992-8. 2002
    ..The present studies were undertaken to investigate whether endothelial dysfunction associated with altered NO-dependent vasodilatation pathways is also observed in a model of in utero programming of hypertension...