Affiliation: University of Toronto
- Effect of iron content on the tolerability of prenatal multivitamins in pregnancyPatricia Nguyen
Department of Pharmaceutical Sciences, Leslie Dan Faculty of Pharmacy, University of Toronto, Toronto, Canada
BMC Pregnancy Childbirth 8:17. 2008....
- Managing nausea and vomiting of pregnancy with pharmacological and nonpharmacological treatmentsPatricia Nguyen
The University of Toronto, The Motherisk Program, The Hospital for Sick Children, Toronto, Canada
Womens Health (Lond Engl) 2:753-60. 2006..The following review provides a detailed description of NVP and how it can adversely affect a woman's life, as well as evidence-based information on treatment strategies...
- Pregnancy-induced changes in the long-term pharmacokinetics of 1.1 mg vs. 5 mg folic acid: a randomized clinical trialMahvash Shere
Leslie Dan Faculty of Pharmacy, University of Toronto, Toronto, Ontario, Canada The Motherisk Program, Division of Clinical Pharmacology and Toxicology, The Hospital for Sick Children, Toronto, Ontario, Canada
J Clin Pharmacol 55:159-67. 2015..Thus, physiological changes in pregnancy alter long-term folate pharmacokinetics. Despite supplementation over an extended period of time, steady-state does not seem to be achieved in either dose group within our study. ..
- Steady state folate concentrations achieved with 5 compared with 1.1 mg folic acid supplementation among women of childbearing agePatricia Nguyen
Department of Pharmaceutical Sciences, Leslie Dan Faculty of Pharmacy, University of Toronto, Toronto, ON, Canada
Am J Clin Nutr 89:844-52. 2009..Women with poor supplement adherence or a previous pregnancy affected by a neural tube defect may need to take higher doses of folic acid (4-5 mg). However, there are limited data on the pharmacokinetics of higher folic acid doses...
- Comparing folic acid pharmacokinetics among women of childbearing age: single dose ingestion of 1.1 versus 5 MG folic acidPatricia Nguyen
Department of Pharmaceutical Sciences, Faculty of Pharmacy, University of Toronto, Toronto, Canada
Can J Clin Pharmacol 15:e314-22. 2008..No human study is presently available which examined the pharmacokinetics of 5 mg folic acid...
- Predictors of prenatal multivitamin adherence in pregnant womenPatricia Nguyen
FRCPC, The Motherisk Program, Hospital for Sick Children, 555 University Avenue, Toronto, ON M5G 1X8
J Clin Pharmacol 49:735-42. 2009..It is concluded that predictors of adherence to recommended prenatal multivitamins during pregnancy are rooted in women's prior experiences with multivitamin use...
- Colchicine poisoning: the dark side of an ancient drugYaron Finkelstein
Division of Clinical Pharmacology and Toxicology, The Hospital for Sick Children, University of Toronto, Toronto, ON, Canada
Clin Toxicol (Phila) 48:407-14. 2010..Although colchicine poisoning is sometimes intentional, unintentional toxicity is common and often associated with a poor outcome...