Pascale F Macgregor

Summary

Affiliation: University of Toronto
Country: Canada

Publications

  1. ncbi request reprint Gene expression in cancer: the application of microarrays
    Pascale F Macgregor
    Microarray Centre, Clinical Genomics Centre, University Health Network, Toronto, ON, Canada
    Expert Rev Mol Diagn 3:185-200. 2003
  2. pmc High-resolution mapping of genomic imbalance and identification of gene expression profiles associated with differential chemotherapy response in serous epithelial ovarian cancer
    Marcus Bernardini
    Ontario Cancer Institute, Princess Margaret Hospital, University Health Network, Toronto, Ontario, Canada
    Neoplasia 7:603-13. 2005
  3. ncbi request reprint Microarray expression identification of differentially expressed genes in serous epithelial ovarian cancer compared with bulk normal ovarian tissue and ovarian surface scrapings
    Dan Grisaru
    Division of Gynecological Oncology, Princess Margaret Hospital, University Health Network, Toronto, Canada
    Oncol Rep 18:1347-56. 2007
  4. ncbi request reprint Application of microarrays to the analysis of gene expression in cancer
    Pascale F Macgregor
    Microarray Centre, Clinical Genomics Center, University Health Network, Toronto, Ontario, M5G 1L7 Canada
    Clin Chem 48:1170-7. 2002
  5. ncbi request reprint Parallel analysis of sporadic primary ovarian carcinomas by spectral karyotyping, comparative genomic hybridization, and expression microarrays
    Jane Bayani
    Ontario Cancer Institute, Princess Margaret Hospital, University Health Network, Toronto, Ontario, Canada
    Cancer Res 62:3466-76. 2002
  6. ncbi request reprint Using microarrays to predict resistance to chemotherapy in cancer patients
    Chung Hae Lee
    Microarray Centre, Clinical Genomics Centre, University Health Network, Canadian Breast Cancer Research Alliance, 790 Bay Street, Ste 1000, Toronto, ON, M5G 1NB, Canada
    Pharmacogenomics 5:611-25. 2004
  7. ncbi request reprint Genetic alterations in doxorubicin-resistant hepatocellular carcinoma cells: a combined study of spectral karyotyping, positional expression profiling and candidate genes
    Ying Hu
    Department of Clinical Oncology, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, New Territories, Hong Kong SAR, China
    Int J Oncol 25:1357-64. 2004
  8. ncbi request reprint Transcriptional profiling identifies gene expression changes associated with IFN-alpha tolerance in hepatitis C-related hepatocellular carcinoma cells
    Nathalie Wong
    Department of Anatomical and Cellular Pathology, Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, N T, Hong Kong
    Clin Cancer Res 11:1319-26. 2005
  9. ncbi request reprint Karyotypic imbalances and differential gene expressions in the acquired doxorubicin resistance of hepatocellular carcinoma cells
    Elizabeth Pang
    Department of Clinical Oncology, Sir YK Pao Centre for Cancer, The Chinese University of Hong Kong, Shatin, NT, Hong Kong SAR, China
    Lab Invest 85:664-74. 2005
  10. ncbi request reprint Transcriptional profiling on chromosome 19p indicated frequent downregulation of ACP5 expression in hepatocellular carcinoma
    Kathy Y Y Chan
    Department of Anatomical and Cellular Pathology, The Chinese University of Hong Kong, People s Republic of China
    Int J Cancer 114:902-8. 2005

Collaborators

Detail Information

Publications10

  1. ncbi request reprint Gene expression in cancer: the application of microarrays
    Pascale F Macgregor
    Microarray Centre, Clinical Genomics Centre, University Health Network, Toronto, ON, Canada
    Expert Rev Mol Diagn 3:185-200. 2003
    ....
  2. pmc High-resolution mapping of genomic imbalance and identification of gene expression profiles associated with differential chemotherapy response in serous epithelial ovarian cancer
    Marcus Bernardini
    Ontario Cancer Institute, Princess Margaret Hospital, University Health Network, Toronto, Ontario, Canada
    Neoplasia 7:603-13. 2005
    ....
  3. ncbi request reprint Microarray expression identification of differentially expressed genes in serous epithelial ovarian cancer compared with bulk normal ovarian tissue and ovarian surface scrapings
    Dan Grisaru
    Division of Gynecological Oncology, Princess Margaret Hospital, University Health Network, Toronto, Canada
    Oncol Rep 18:1347-56. 2007
    ..Gene expression profiling and sequential statistical analyses of gene subsets can identify new genes and molecular pathways affecting development of SEOC. The genes of interest can be potential targets for future research of SEOC...
  4. ncbi request reprint Application of microarrays to the analysis of gene expression in cancer
    Pascale F Macgregor
    Microarray Centre, Clinical Genomics Center, University Health Network, Toronto, Ontario, M5G 1L7 Canada
    Clin Chem 48:1170-7. 2002
    ....
  5. ncbi request reprint Parallel analysis of sporadic primary ovarian carcinomas by spectral karyotyping, comparative genomic hybridization, and expression microarrays
    Jane Bayani
    Ontario Cancer Institute, Princess Margaret Hospital, University Health Network, Toronto, Ontario, Canada
    Cancer Res 62:3466-76. 2002
    ..5-3p21.31 and increased expression of genes from 3q13.33-3q28. This study demonstrates that SKY, CGH, and microarray analysis can in combination identify significantly smaller subsets of differentially expressed genes for future studies...
  6. ncbi request reprint Using microarrays to predict resistance to chemotherapy in cancer patients
    Chung Hae Lee
    Microarray Centre, Clinical Genomics Centre, University Health Network, Canadian Breast Cancer Research Alliance, 790 Bay Street, Ste 1000, Toronto, ON, M5G 1NB, Canada
    Pharmacogenomics 5:611-25. 2004
    ..It also highlights some recent examples of microarray studies, which represent a first step toward a better understanding of drug resistance in cancer and, ultimately, personalized medicine...
  7. ncbi request reprint Genetic alterations in doxorubicin-resistant hepatocellular carcinoma cells: a combined study of spectral karyotyping, positional expression profiling and candidate genes
    Ying Hu
    Department of Clinical Oncology, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, New Territories, Hong Kong SAR, China
    Int J Oncol 25:1357-64. 2004
    ..Our present study highlights the usefulness of multimodality approaches in identifying genetic markers, and further describes the novel finding of ECHS1 down-regulation in the DX chemo-resistance of HCC...
  8. ncbi request reprint Transcriptional profiling identifies gene expression changes associated with IFN-alpha tolerance in hepatitis C-related hepatocellular carcinoma cells
    Nathalie Wong
    Department of Anatomical and Cellular Pathology, Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, N T, Hong Kong
    Clin Cancer Res 11:1319-26. 2005
    ..Hence, delineation of molecular targets implicated in the resistant pathway holds value in refining the therapeutic benefits of IFN-alpha...
  9. ncbi request reprint Karyotypic imbalances and differential gene expressions in the acquired doxorubicin resistance of hepatocellular carcinoma cells
    Elizabeth Pang
    Department of Clinical Oncology, Sir YK Pao Centre for Cancer, The Chinese University of Hong Kong, Shatin, NT, Hong Kong SAR, China
    Lab Invest 85:664-74. 2005
    ..Our present study highlighted areas of genomic imbalances and candidate genes in the acquired doxorubicin-resistance behavior of HCC cells...
  10. ncbi request reprint Transcriptional profiling on chromosome 19p indicated frequent downregulation of ACP5 expression in hepatocellular carcinoma
    Kathy Y Y Chan
    Department of Anatomical and Cellular Pathology, The Chinese University of Hong Kong, People s Republic of China
    Int J Cancer 114:902-8. 2005
    ..001). In our study, the novel finding of common ACP5 downregulation in HCC may provide basis for further investigations on the role of acid phosphatase in hepatocarcinogenesis...