Adeera Levin

Summary

Affiliation: University of British Columbia
Country: Canada

Publications

  1. doi request reprint Novel biomarkers do not correlate with severity of vascular stiffness in CKD patients with severe co-morbid disease
    Catherine Weber
    Division of Nephrology, Department of Medicine, University of British Columbia, Vancouver, B C, Canada
    Nephron Clin Pract 119:c261-8. 2011
  2. doi request reprint Matrix metalloproteinase-2 and -9 exacerbate arterial stiffening and angiogenesis in diabetes and chronic kidney disease
    Ada W Y Chung
    Department of Cardiovascular Science, Child and Family Research Institute, University of British Columbia, Vancouver, BC, Canada V5Z 4H4
    Cardiovasc Res 84:494-504. 2009
  3. doi request reprint Arterial stiffness and functional properties in chronic kidney disease patients on different dialysis modalities: an exploratory study
    Ada W Y Chung
    Department of Cardiovascular Science, Child and Family Research Institute, University of British Columbia, Vancouver, Canada
    Nephrol Dial Transplant 25:4031-41. 2010
  4. ncbi request reprint Canadian randomized trial of hemoglobin maintenance to prevent or delay left ventricular mass growth in patients with CKD
    Adeera Levin
    University of British Columbia, St Paul s Hospital, Vancouver, British Columbia, Canada
    Am J Kidney Dis 46:799-811. 2005
  5. pmc Exploration of association of 1,25-OH2D3 with augmentation index, a composite measure of arterial stiffness
    Jason Andrade
    Department of Medicine, University of British Columbia, Saint Paul s Hospital, Vancouver, BC, Canada
    Clin J Am Soc Nephrol 3:1800-6. 2008
  6. doi request reprint Differential microvasculature dysfunction in living kidney donor transplant recipients: nondialyzed versus dialyzed chronic kidney disease patients
    Ada W Y Chung
    Department of Cardiovascular Science, Child and Family Research Institute, University of British Columbia, Vancouver, BC, Canada
    J Vasc Res 47:128-38. 2010
  7. doi request reprint Individuals of Pacific Asian origin with IgA nephropathy have an increased risk of progression to end-stage renal disease
    Sean J Barbour
    1 Division of Nephrology, Department of Medicine, University of British Columbia, Vancouver, British Columbia, Canada 2 British Columbia Provincial Renal Agency, Vancouver, British Columbia, Canada 3 Toronto Glomerulonephritis Registry, University Health Network, Toronto, Ontario, Canada
    Kidney Int 84:1017-24. 2013
  8. doi request reprint Towards rational approaches of health care utilization in complex patients: an exploratory randomized trial comparing a novel combined clinic to multiple specialty clinics in patients with renal disease-cardiovascular disease-diabetes
    Catherine Weber
    Department of Medicine, Division of Nephrology, St Paul s Hospital, University of British Columbia, Vancouver, Canada
    Nephrol Dial Transplant 27:iii104-10. 2012
  9. doi request reprint Variability and risk factors for kidney disease progression and death following attainment of stage 4 CKD in a referred cohort
    Adeera Levin
    Division of Nephrology, University of British Columbia, BC Provincial Renal Agency, Vancouver, British Columbia, Canada
    Am J Kidney Dis 52:661-71. 2008
  10. doi request reprint Incidental atherosclerotic renal artery stenosis diagnosed at cardiac catheterization: no difference in kidney function with or without stenting
    Nadia Zalunardo
    Division of Nephrology, Department of Medicine, University of British Columbia, Vancouver, British Columbia, Canada
    Am J Nephrol 28:921-8. 2008

Detail Information

Publications79

  1. doi request reprint Novel biomarkers do not correlate with severity of vascular stiffness in CKD patients with severe co-morbid disease
    Catherine Weber
    Division of Nephrology, Department of Medicine, University of British Columbia, Vancouver, B C, Canada
    Nephron Clin Pract 119:c261-8. 2011
    ..Novel biomarkers may help explain the pathobiology of vascular disease in chronic kidney disease, and thus set the stage for identification of therapeutic targets, potential reversibility, and improved outcomes in this population...
  2. doi request reprint Matrix metalloproteinase-2 and -9 exacerbate arterial stiffening and angiogenesis in diabetes and chronic kidney disease
    Ada W Y Chung
    Department of Cardiovascular Science, Child and Family Research Institute, University of British Columbia, Vancouver, BC, Canada V5Z 4H4
    Cardiovasc Res 84:494-504. 2009
    ..We hypothesized that MMP-2 and -9 were up-regulated in the arterial vasculature from CKD patients with diabetes, compared with those without diabetes...
  3. doi request reprint Arterial stiffness and functional properties in chronic kidney disease patients on different dialysis modalities: an exploratory study
    Ada W Y Chung
    Department of Cardiovascular Science, Child and Family Research Institute, University of British Columbia, Vancouver, Canada
    Nephrol Dial Transplant 25:4031-41. 2010
    ..Dialysis modalities, peritoneal dialysis (PD) and haemodialysis (HD) may differentially impact on vascular function and oxidative stress...
  4. ncbi request reprint Canadian randomized trial of hemoglobin maintenance to prevent or delay left ventricular mass growth in patients with CKD
    Adeera Levin
    University of British Columbia, St Paul s Hospital, Vancouver, British Columbia, Canada
    Am J Kidney Dis 46:799-811. 2005
    ..Study design and sample size calculations were based on previously published Canadian data...
  5. pmc Exploration of association of 1,25-OH2D3 with augmentation index, a composite measure of arterial stiffness
    Jason Andrade
    Department of Medicine, University of British Columbia, Saint Paul s Hospital, Vancouver, BC, Canada
    Clin J Am Soc Nephrol 3:1800-6. 2008
    ..Central arterial stiffness can be measured using noninvasive technologies, including augmentation index (AIx), a composite measure of arterial stiffness...
  6. doi request reprint Differential microvasculature dysfunction in living kidney donor transplant recipients: nondialyzed versus dialyzed chronic kidney disease patients
    Ada W Y Chung
    Department of Cardiovascular Science, Child and Family Research Institute, University of British Columbia, Vancouver, BC, Canada
    J Vasc Res 47:128-38. 2010
    ..282, p = 0.01). In conclusion, we have uniquely demonstrated differential microvasculature dysfunction between nondialyzed and dialyzed CKD patients...
  7. doi request reprint Individuals of Pacific Asian origin with IgA nephropathy have an increased risk of progression to end-stage renal disease
    Sean J Barbour
    1 Division of Nephrology, Department of Medicine, University of British Columbia, Vancouver, British Columbia, Canada 2 British Columbia Provincial Renal Agency, Vancouver, British Columbia, Canada 3 Toronto Glomerulonephritis Registry, University Health Network, Toronto, Ontario, Canada
    Kidney Int 84:1017-24. 2013
    ..5) and an increased risk of a reduction in eGFR by half (hazard ratio 1.81, 95% CI 1.25, 2.62). Thus, in a large multiracial cohort of patients with IgAN, individuals of Pacific Asian origin have a higher risk of progression to ESRD...
  8. doi request reprint Towards rational approaches of health care utilization in complex patients: an exploratory randomized trial comparing a novel combined clinic to multiple specialty clinics in patients with renal disease-cardiovascular disease-diabetes
    Catherine Weber
    Department of Medicine, Division of Nephrology, St Paul s Hospital, University of British Columbia, Vancouver, Canada
    Nephrol Dial Transplant 27:iii104-10. 2012
    ..We sought to examine if streamlining medical care of complex patients (two or more conditions) is associated with similar, worse or improved outcomes using a randomized controlled study design...
  9. doi request reprint Variability and risk factors for kidney disease progression and death following attainment of stage 4 CKD in a referred cohort
    Adeera Levin
    Division of Nephrology, University of British Columbia, BC Provincial Renal Agency, Vancouver, British Columbia, Canada
    Am J Kidney Dis 52:661-71. 2008
    ..The objectives of this analysis are to describe the predictors of rapid progression of kidney disease and death in patients followed up by nephrologists...
  10. doi request reprint Incidental atherosclerotic renal artery stenosis diagnosed at cardiac catheterization: no difference in kidney function with or without stenting
    Nadia Zalunardo
    Division of Nephrology, Department of Medicine, University of British Columbia, Vancouver, British Columbia, Canada
    Am J Nephrol 28:921-8. 2008
    ....
  11. ncbi request reprint N-acetylcysteine reduces urinary albumin excretion following contrast administration: evidence of biological effect
    Adeera Levin
    Division of Nephrology, Room 6010, Providence Health Care Saint Paul s Hospital, University of British Columbia, 1081 Burrard Street, Vancouver V6Z 1Y6, BC, Canada
    Nephrol Dial Transplant 22:2520-4. 2007
    ....
  12. pmc Patient and technique survival among a Canadian multicenter nocturnal home hemodialysis cohort
    Robert P Pauly
    Division of Nephrology, Department of Medicine, University of Alberta, Edmonton, Alberta, Canada
    Clin J Am Soc Nephrol 5:1815-20. 2010
    ..This study addressed this gap in knowledge...
  13. doi request reprint Vascular stiffness in incident peritoneal dialysis patients over time
    Mila Tang
    Division of Nephrology, University of British Columbia
    Clin Nephrol 78:254-62. 2012
    ..Vascular stiffness is prevalent in end-stage renal disease patients and predicts adverse events. This study describes the prevalence of vascular stiffness and its associated factors in a cohort of incident peritoneal dialysis (PD) patients...
  14. ncbi request reprint Conservative outpatient renoprotective protocol in patients with low GFR undergoing contrast angiography: a case series
    Paul Komenda
    Department of Medicine, Division of Nephrology, St Paul s Hospital, Division of Nephrology, University of British Columbia, 1081 Burrard Street, Providence Wing RM 6010A, Vancouver, BC, Canada
    Clin Exp Nephrol 11:209-13. 2007
    ..For this reason potentially life-saving procedures such as angiography are sometimes withheld or delayed...
  15. doi request reprint A comparison of the predictive performance of different methods of kidney function estimation in a well-characterized HIV-infected population
    Katherine Barraclough
    Division of Nephrology, University of British Columbia, Vancouver, B C, Canada
    Nephron Clin Pract 111:c39-48. 2009
    ..Glomerular filtration rate (GFR) estimation equations have never been validated in the HIV population. This pilot study aimed to compare all currently available methods of kidney function assessment with nuclear GFR in HIV-infected adults...
  16. doi request reprint Differences in progression of CKD and mortality amongst Caucasian, Oriental Asian and South Asian CKD patients
    Sean J Barbour
    Department of Medicine, University of British Columbia, Vancouver, Canada
    Nephrol Dial Transplant 25:3663-72. 2010
    ..Ethnic differences in chronic kidney disease (CKD) progression are not well characterized but are of interest across and within countries...
  17. doi request reprint Biomarkers in native and transplant kidneys: opportunities to improve prediction of outcomes in chronic kidney disease
    Sacha A De Serres
    Transplantation Unit, Renal Division, Department of Medicine, CHUQ L Hôtel Dieu de Québec, Universite Laval, Quebec, Quebec, Canada
    Curr Opin Nephrol Hypertens 21:619-27. 2012
    ..This review examines the current state of conventional and nonconventional biomarkers as noninvasive tools to improve risk-stratification and outcome prediction in CKD...
  18. ncbi request reprint Outcomes after percutaneous coronary interventions in patients with CKD: improved outcome in the stenting era
    Caroline Stigant
    Department of Health Care and Epidemiology, St Paul s Hospital, University of British Columbia, Vancouver, BC, Canada
    Am J Kidney Dis 45:1002-9. 2005
    ..The benefit of stents in high-risk patients normally excluded from clinical trials has not been well studied. Outcomes after PCIs in patients with chronic kidney disease (CKD) before and after widespread use of stents were compared...
  19. doi request reprint Outcomes of vascular access creation prior to dialysis: building the case for early referral
    Catherine L Weber
    Division of Nephrology, Department of Medicine, University British Columbia, Vancouver, British Columbia, Canada
    ASAIO J 55:355-60. 2009
    ..001). In conclusion, the success rate of early AVF creation is reasonable and complications when identified can be remedied without the need for a catheter, thus ultimately maximizing the use of AVF in dialysis patients...
  20. doi request reprint Biomarkers of inflammation, fibrosis, cardiac stretch and injury predict death but not renal replacement therapy at 1 year in a Canadian chronic kidney disease cohort
    Adeera Levin
    University of British Columbia, Vancouver, Canada
    Nephrol Dial Transplant 29:1037-47. 2014
    ..We assessed whether these newer biomarkers, alone or as a panel, improve risk prediction for renal replacement therapy or death, over and above conventional clinical, demographic and laboratory variables...
  21. doi request reprint Incident isolated 1,25(OH)(2)D(3) deficiency is more common than 25(OH)D deficiency in CKD
    Adeera Levin
    BC Provincial Renal Agency, Vancouver, British Columbia, Canada
    J Nephrol 25:204-10. 2012
    ....
  22. pmc Intensive hemodialysis associates with improved survival compared with conventional hemodialysis
    Gihad E Nesrallah
    Division of Nephrology, University of Western Ontario, London, Ontario, Canada
    J Am Soc Nephrol 23:696-705. 2012
    ..In conclusion, there is a strong association between intensive home hemodialysis and improved survival, but whether this relationship is causal remains unknown...
  23. doi request reprint Diabetes, kidney disease and cardiovascular disease patients. Assessing care of complex patients using outpatient testing and visits: additional metrics by which to evaluate health care system functioning
    Adeera Levin
    University of British Columbia, Vancouver, Canada
    Nephrol Dial Transplant 24:2714-20. 2009
    ..Patients with these conditions contribute excessively to health care costs. Opportunities for system redesign require metrics by which to evaluate the impact...
  24. doi request reprint Outcomes of a provincial home haemodialysis programme--a two-year experience: establishing benchmarks for programme evaluation
    Paul Komenda
    Division of Nephrology, University of British Columbia, Vancouver, British Columbia, Canada
    Nephrol Dial Transplant 23:2647-52. 2008
    ..HHD programmes have reported successful outcomes with respect to patients' well-being, haemodynamic stability and improvement of clinical and biochemical parameters in small selected groups of patients...
  25. doi request reprint The cost of starting and maintaining a large home hemodialysis program
    Paul Komenda
    British Columbia Provincial Renal Agency, Vancouver, Canada
    Kidney Int 77:1039-45. 2010
    ..Consideration of hidden costs is important for administrators and planners to take into account when designing budgets for home hemodialysis...
  26. pmc Chronic kidney disease, heart failure and anemia
    Sean A Virani
    University of British Columbia, Vancouver, British Columbia
    Can J Cardiol 24:22B-4B. 2008
    ..Future research in this arena must focus on the optimal dose of erythropoietin administered to hemoglobin level achieved that will result in improved cardiovascular outcomes for patients with heart failure and kidney disease...
  27. doi request reprint Evaluation of creatinine-based formulas in dosing adjustment of cancer drugs other than carboplatin
    Sarah Jennings
    Provincial Systemic Therapy Program, BC Cancer Agency, Vancouver, BC, Canada
    J Oncol Pharm Pract 16:113-9. 2010
    ..Since this setting does not include routine measurement of GFR, we report the concordance of estimates of GFR derived from the CG and MDRD formulas...
  28. ncbi request reprint Analysis of cardiovascular disease and kidney outcomes in multidisciplinary chronic kidney disease clinics: complex disease requires complex care models
    Paul Komenda
    Division of Nephrology, University of British Columbia, Vancouver, British Columbia, Canada
    Curr Opin Nephrol Hypertens 15:61-6. 2006
    ..Specifically we examine the rationale and outcomes of those seen in multidisciplinary clinics...
  29. ncbi request reprint Renal safety of 1-hour pamidronate infusion for breast cancer and multiple myeloma patients: comparison between clinical trials and population-based database
    Mario L de Lemos
    Provincial Systemic Therapy Program, British Columbia Cancer Agency, Vancouver, BC, Canada
    J Oncol Pharm Pract 12:193-9. 2006
    ..The American Society of Clinical Oncology recommends infusion of pamidronate over 2 hours to avoid renal deterioration, although there are data to suggest that 1-hour infusions may be safe...
  30. ncbi request reprint The short- and long-term impact of multi-disciplinary clinics in addition to standard nephrology care on patient outcomes
    Bryan M Curtis
    Division of Nephrology, Patient Research Center, Memorial University of Newfoundland, Canada
    Nephrol Dial Transplant 20:147-54. 2005
    ..This two country case control study of incident dialysis patients evaluates the outcomes of patients exposed to formalized multi-disciplinary clinic (MDC) programmes vs standard nephrologist care...
  31. doi request reprint Multi-intervention management of calciphylaxis: a report of 7 cases
    Corisande Baldwin
    Department of Medicine, University of British Columbia, Vancouver, British Columbia, Canada
    Am J Kidney Dis 58:988-91. 2011
    ..We suggest that consistent implementation of a multi-interventional approach may alter the course of this devastating disease. Further studies are needed to confirm and extend these findings...
  32. ncbi request reprint Haemoglobin at time of referral prior to dialysis predicts survival: an association of haemoglobin with long-term outcomes
    Adeera Levin
    Division of Nephrology, University of British Columbia, 1081 Burrard Street, Rm 6010A, Vancouver BC Canada V6Z1Y8
    Nephrol Dial Transplant 21:370-7. 2006
    ..Substantial variation in Hgb values exists at all GFR levels. These findings underscore the importance of evaluating Hgb at all GFR levels, and the need to study the impact of modification of Hgb at different GFR levels on survival...
  33. doi request reprint CKD stage at nephrology referral and factors influencing the risks of ESRD and death
    Maneesh Sud
    Department of Medicine, University of Toronto, Toronto, Ontario, Canada
    Am J Kidney Dis 63:928-36. 2014
    ..Our objective was to apply a competing risk analysis in order to estimate these risks in a referred cohort of patients with CKD by stage at referral and identify risk factors associated with each outcome...
  34. pmc Cohort profile: Canadian study of prediction of death, dialysis and interim cardiovascular events (CanPREDDICT)
    Adeera Levin
    University of British Columbia, 1081 Burrard Street Room 6010A, Vancouver, BC V6Z1Y6, Canada
    BMC Nephrol 14:121. 2013
    ..This information could then be used to better understand biological variation in outcomes, to develop clinical prediction models and to inform enrolment into interventional studies which may lead to novel treatments...
  35. doi request reprint Responsiveness of FGF-23 and mineral metabolism to altered dietary phosphate intake in chronic kidney disease (CKD): results of a randomized trial
    Mhairi Sigrist
    Division of Nephrology, University of British Columbia, Vancouver, British Columbia, Canada
    Nephrol Dial Transplant 28:161-9. 2013
    ..We studied the responsiveness of FGF-23 and mineral metabolism to altered dietary phosphate intake in chronic kidney disease (CKD) and healthy control patients...
  36. ncbi request reprint A randomized controlled trial of intravenous N-acetylcysteine for the prevention of contrast-induced nephropathy after cardiac catheterization: lack of effect
    John G Webb
    Division of Cardiology, Pharmacy Department, St Paul s Hospital, University of British Columbia, Vancouver, British Columbia, Canada
    Am Heart J 148:422-9. 2004
    ..The objective of this study was to evaluate, in a blinded, randomized, placebo-controlled fashion, whether intravenous NAC reduced CIN in the setting of cardiac catheterization in patients with preexisting renal insufficiency...
  37. doi request reprint Vitamin D and parathyroid hormone in general populations: understandings in 2009 and applications to chronic kidney disease
    Manraj Johal
    Division of Nephrology, University of British Columbia, Vancouver BC, Canada V6Z 1Y8
    Clin J Am Soc Nephrol 4:1508-14. 2009
    ..Some recommendations for pragmatic approaches and study design are suggested...
  38. ncbi request reprint Evaluation of predictive formulae for glomerular filtration rate for carboplatin dosing in gynecological malignancies
    Mario L de Lemos
    Provincial Drug Information Coordinator, Provincial Systemic Therapy Program, British Columbia Cancer Agency, 600 West 10th Avenue, Vancouver, BC, V5Z 4E6, Canada
    Gynecol Oncol 103:1063-9. 2006
    ..The MDRD formula has been shown to be more accurate in non-cancer patients with chronic renal disease. We compared the accuracy of these formulae for dosing carboplatin in patients with gynecological cancers...
  39. pmc Coronary artery calcification scores in patients with chronic kidney disease prior to dialysis: reliability as a trial outcome measure
    Katherine A Barraclough
    Division of Nephrology, University of British Columbia, Vancouver, British Columbia, Canada
    Nephrol Dial Transplant 23:3199-205. 2008
    ....
  40. ncbi request reprint Surveillance cultures of tunneled cuffed catheter exit sites in chronic hemodialysis patients are of no benefit
    Debbie Rosenbaum
    Division of Nephrology, St Paul s Hospital, University of British Columbia, Vancouver, BC, Canada
    Hemodial Int 10:365-70. 2006
    ..16.7%, p > 0.05). The strategy of treating positive surveillance cultures is not beneficial. Positive Ssc do not predict the occurrence of catheter-related infection, and treatment of these cultures may lead to increased infection rates...
  41. doi request reprint Urinary NGAL levels before and after coronary angiography: a complex story
    Catherine L Weber
    Division of Nephrology, Department of Medicine, University of British Columbia, Vancouver, British Columbia, Canada
    Nephrol Dial Transplant 26:3207-11. 2011
    ..We describe urinary neutrophil gelatinase-associated lipocalin (uNGAL) values in association with clinical characteristics and urinary parameters in adults undergoing coronary angiography...
  42. pmc Age and association of kidney measures with mortality and end-stage renal disease
    Stein I Hallan
    Division of Nephrology, Department of Medicine, St Olav University Hospital, and Faculty of Medicine, Norwegian University of Science and Technology, Trondheim, Norway
    JAMA 308:2349-60. 2012
    ..Chronic kidney disease (CKD) is prevalent in older individuals, but the risk implications of low estimated glomerular filtration rate (eGFR) and high albuminuria across the full age range are controversial...
  43. ncbi request reprint An unusual case of acute kidney injury due to vancomycin lessons learnt from reliance on eGFR
    Katherine Barraclough
    Department of Nephrology, St Paul s Hospital, Vancouver, British Colombia, V6Z1Y6, Canada
    Nephrol Dial Transplant 22:2391-4. 2007
    ..We support ongoing efforts to develop or refine equations for specific unique and easily identifiable populations...
  44. ncbi request reprint Central vein stenosis: a common problem in patients on hemodialysis
    Jennifer M MacRae
    Division of Nephrology, University of British Columbia, Vancouver, Canada
    ASAIO J 51:77-81. 2005
    ..Thus further studies should attempt to determine the true incidence of this problem and ultimately address the optimal treatment strategies...
  45. ncbi request reprint N-acetylcysteine for prevention of radiographic contrast material-induced nephropathy: is the intravenous route best?
    Stephen J Shalansky
    Pharmacy Department, St Paul s Hospital, and Faculty of Pharmaceutical Sciences, University of British Columbia, Vancouver, British Columbia, Canada
    Pharmacotherapy 25:1095-103. 2005
    ....
  46. ncbi request reprint Use of GFR equations to adjust drug doses in an elderly multi-ethnic group--a cautionary tale
    Jagbir Gill
    Division of Nephrology, UBC, Centre for Health Evaluation and Outcome Sciences, Vancouver, BC, Canada
    Nephrol Dial Transplant 22:2894-9. 2007
    ..A cross-sectional study of long-term care facility patients was conducted to demonstrate the impact of the use of different formulae in the elderly for the purposes of medication dosing...
  47. doi request reprint Utility and limitations of a multicenter nocturnal home hemodialysis cohort
    Robert P Pauly
    Department of Medicine, Division of Nephrology, University of Alberta, Edmonton, Alberta, Canada
    Clin J Am Soc Nephrol 3:1846-51. 2008
    ....
  48. pmc An overview of the British Columbia Glomerulonephritis network and registry: integrating knowledge generation and translation within a single framework
    Sean Barbour
    Division of Nephrology, University of British Columbia, Vancouver, BC, Canada
    BMC Nephrol 14:236. 2013
    ..6 million people. This provincial initiative will serve as a model for Canadian or other national and international endeavours...
  49. doi request reprint Disease-specific risk of venous thromboembolic events is increased in idiopathic glomerulonephritis
    Sean J Barbour
    Division of Nephrology, Department of Medicine, University of British Columbia, Vancouver, British Columbia, Canada
    Kidney Int 81:190-5. 2012
    ..Thus, in this large cohort, histologic diagnosis was an independent risk factor for venous thromboembolic events. Further studies are needed to discover mechanisms responsible for this high risk in patients with membranous nephropathy...
  50. doi request reprint Use of electron-beam sterilized hemodialysis membranes and risk of thrombocytopenia
    Mercedeh Kiaii
    Division of Nephrology, University of British Columbia, 602 1160 Burrard St, Vancouver, BC V6Z 2E8, Canada
    JAMA 306:1679-87. 2011
    ....
  51. ncbi request reprint C-reactive protein levels in patients on maintenance hemodialysis: reliability and reflection on the utility of single measurements
    Caroline E Stigant
    Kidney Foundation of Canada Research Fellow, Division of Nephrology, University of British Columbia, British Columbia, Canada
    Int Urol Nephrol 37:133-40. 2005
    ..We prospectively obtained multiple CRP values in stable patients, hypothesizing that values would remain stable in the absence of disease and that a single CRP value would be a reliable marker of risk...
  52. ncbi request reprint The treatment of anemia in chronic kidney disease: understandings in 2006
    Adeera Levin
    Division of Nephrology, University of British Columbia, St Paul s Hospital, Vancouver, British Columbia, Canada
    Curr Opin Nephrol Hypertens 16:267-71. 2007
    ..It is important for clinical care to identify appropriate treatments and targets for hemoglobin. This review describes current understandings of the treatment of anemia using the most recent published articles...
  53. ncbi request reprint Kidney function and mortality among patients with left ventricular systolic dysfunction
    Nadia A Khan
    Division of Internal Medicine, University of British Columbia, Department of Medicine, 620 B, 1081 Burrard Street, Vancouver, BC, Canada, V6Z 1Y6
    J Am Soc Nephrol 17:244-53. 2006
    ..Rate of decline in kidney function is a strong predictor of increased mortality in this population, independent of worsening heart failure and baseline kidney function...
  54. doi request reprint Variability of hepatitis B testing in British Columbian ESRD patients: the case to focus on implementation of guidelines
    Monica Beaulieu
    Division of Nephrology, University of British Columbia, Vancouver, British Columbia, Canada
    Am J Kidney Dis 52:939-46. 2008
    ..Hepatitis B virus (HBV) immunization protocols are routinely followed in dialysis units. Recommendations for retesting and booster dose administration are variable and less well known...
  55. pmc A randomized control trial to assess the impact of vitamin D supplementation compared to placebo on vascular stiffness in chronic kidney disease patients
    Adeera Levin
    University of British Columbia, 1081 Burrard Street, Room 6010A, Vancouver, BC V6Z 1Y6, Canada
    BMC Cardiovasc Disord 14:156. 2014
    ..A understanding of the mechanism by which different vitamin D compounds confer CV protection in CKD is important for the design of future studies...
  56. doi request reprint Combination hemodialysis and centrifugal therapeutic plasma exchange: 18 years of Canadian experience
    Myriam Farah
    Divisions of Nephrology, University of British Columbia, Vancouver, Canada
    Hemodial Int 17:256-65. 2013
    ..Combination HD and TPE is safe, efficient, and requires less human resources and time than conventional sequential therapy. It should be considered in patients whose treatment regimen includes HD and TPE...
  57. doi request reprint Targets, trends, excesses, and deficiencies: refocusing clinical investigation to improve patient outcomes
    Adeera Levin
    Division of Nephrology, University of British Columbia, Vancouver, British Columbia, Canada
    Kidney Int 83:1001-9. 2013
    ..Improved understanding of pathophysiological mechanisms, in conjunction with more innovative but stringent clinical trial design, will ultimately lead to improved patient outcomes...
  58. doi request reprint Knowledge translation for nephrologists: strategies for improving the identification of patients with proteinuria
    Brenda R Hemmelgarn
    Department of Medicine, University of Calgary, Calgary, Alberta, Canada
    J Nephrol 25:933-43. 2012
    ..These considerations are relevant for dissemination and implementation of guidelines on other topics and in other clinical settings...
  59. doi request reprint Low birth weight and nephron mass and their role in the progression of chronic kidney disease: a case report on identical twins with Alport disease
    Tasleem Rajan
    Department of Medicine, University of British Columbia, Vancouver, Canada
    Nephrol Dial Transplant 26:4136-9. 2011
    ..We suggest further studies and surveillance for this high-risk group of infants in order to gain additional insights into the impact of perinatal factors such as LBW...
  60. ncbi request reprint The profile of cardiac patients with renal artery stenosis
    Christopher E Buller
    Department of Medicine, Division of Cardiology, University of British Columbia, Vancouver, Canada
    J Am Coll Cardiol 43:1606-13. 2004
    ....
  61. ncbi request reprint Short and long alteplase dwells in dysfunctional hemodialysis catheters
    Jennifer Marie Macrae
    Division of Nephrology, St Paul s Hospital, Univeristy of British Columbia, Vancouver, British Columbia, Canada
    Hemodial Int 9:189-95. 2005
    ..The purpose of this study was to determine if TPA dwell time affects short- or long-term catheter patency rates...
  62. doi request reprint Analysis of multidisciplinary care models and interface with primary care in management of chronic kidney disease
    Monica Beaulieu
    Division of Nephrology, University of British Columbia, Vancouver, British Columbia, Canada
    Semin Nephrol 29:467-74. 2009
    ....
  63. ncbi request reprint Anemia and the heart in chronic kidney disease
    Nadia Zalunardo
    Kidney Foundation of Canada, Clinical Investigator Program, Vancouver, British Columbia, Canada
    Semin Nephrol 26:290-5. 2006
    ....
  64. ncbi request reprint Kidneys, hearts, hormones and immunomodulators: integrated understandings
    Adeera Levin
    University of British Columbia, St Paul s Hospital, Vancouver, Canada
    Blood Purif 24:46-50. 2006
    ....
  65. doi request reprint Upregulation of matrix metalloproteinase-2 in the arterial vasculature contributes to stiffening and vasomotor dysfunction in patients with chronic kidney disease
    Ada W Y Chung
    Department of Cardiovascular Science, Child and Family Research Institute, University of British Columbia, Vancouver, British Columbia, Canada
    Circulation 120:792-801. 2009
    ....
  66. doi request reprint Early detection of CKD: the benefits, limitations and effects on prognosis
    Adeera Levin
    Division of Nephrology, University of British Columbia, 1081 Burrard Street, Room 60101A, Vancouver, BC V6Z1Y8, Canada alevin providencehealth bc ca
    Nat Rev Nephrol 7:446-57. 2011
    ..In addition, this article highlights what is currently known about cardiovascular and renal outcomes and the effects of intervention in patients with CKD...
  67. doi request reprint Nondialysis chronic kidney disease in 2011: Progression, prediction, populations and possibilities
    Adeera Levin
    Division of Nephrology, Department of Medicine, St Paul s Hospital, University of British Columbia, 1081 Burrard Street, Room 6010 A, Vancouver, BC V6Z 1Y6, Canada
    Nat Rev Nephrol 8:70-2. 2012
    ....
  68. ncbi request reprint Cardiovascular events and investigation in patients who are awaiting cadaveric kidney transplantation
    John S Gill
    Division of Nephrology, University of British Columbia, St Paul s Hospital, Providence 6a, 1081 Burrard Street, Vancouver, BC, Canada V6Z 1Y6
    J Am Soc Nephrol 16:808-16. 2005
    ..Initial cardiac investigations have limited value in guiding the timing of patient reevaluation after wait-listing. Periodic surveillance cardiac investigation after wait-listing may be unnecessary and requires further study...
  69. ncbi request reprint Successful reintroduction of a different erythropoiesis-stimulating agent after pure red cell aplasia: relapse after successful therapy with prednisone
    Jason Andrade
    Department of Medicine, University of British Columbia, St Paul s Hospital, Vancouver BC, Canada
    Nephrol Dial Transplant 20:2548-51. 2005
    ..It appears that there may be problems associated with discontinuation of immunosuppressive therapy in the presence of sustained erythropoiesis-stimulating agent therapy in those in whom the condition has occurred previously...
  70. pmc Exploring the Relationships between Hemoglobin, the Endothelium and Vascular Health in Patients with Chronic Kidney Disease
    Catherine Weber
    Division of Nephrology, Department of Medicine, University of British Columbia, St Paul s Hospital, Vancouver, B C, Canada
    Nephron Extra 1:190-200. 2011
    ..Ultimately, individualized targets may depend upon the properties of the patient's endothelial and vascular milieu, and thus the complex relationships between these factors need to be further explored...
  71. doi request reprint Systematic review of evidence for the use of intradialytic parenteral nutrition in malnourished hemodialysis patients
    Mhairi K Sigrist
    Department of Nephrology, University of British Columbia, St Paul s Hospital, Vancouver, British Columbia, Canada
    J Ren Nutr 20:1-7. 2010
    ..This study systematically reviews the current literature, to assess whether IDPN improves survival, quality of life, or nutritional status in those receiving maintenance HD...
  72. ncbi request reprint Prognostic value of troponin T and I among asymptomatic patients with end-stage renal disease: a meta-analysis
    Nadia A Khan
    Division of Internal Medicine, University of British Columbia, Canada
    Circulation 112:3088-96. 2005
    ....
  73. pmc Screening for Fabry disease in patients with chronic kidney disease: limitations of plasma alpha-galactosidase assay as a screening test
    Jason Andrade
    Department of Medicine, University of British Columbia, Vancouver, British Columbia, Canada
    Clin J Am Soc Nephrol 3:139-45. 2008
    ..This study sought to determine the prevalence of Fabry disease in a multiethnic male chronic kidney disease population, involving dialysis-dependent, non-dialysis-dependent, and transplant patients...
  74. doi request reprint Implementing a home haemodialysis programme without adversely affecting a peritoneal dialysis programme
    Michael Copland
    British Columbia Renal Agency, Division of Nephrology, University of British Columbia, Vancouver, BC V5Z 1M9, Canada
    Nephrol Dial Transplant 24:2546-50. 2009
    ..This study attempts to look at the impact of a new home haemodialysis programme on an existing peritoneal dialysis programme in the province of British Columbia...
  75. pmc Nephrology: 4. Strategies for the care of adults with chronic kidney disease
    Caroline Stigant
    University of British Columbia, Vancouver, BC
    CMAJ 168:1553-60. 2003
  76. ncbi request reprint Executing change in the management of chronic kidney disease: perspectives on guidelines and practice
    Adeera Levin
    Nephrology Education and Research, St Paul s Hospital, 1081 Burrard Street, Room 6010A, Vancouver, BC V6Z 1Y6, Canada
    Med Clin North Am 89:701-9. 2005
    ..The systematic evaluation of all patients and incorporation of simplified definitions and classification systems should enhance the ability to improve the outcomes of patients with kidney disease irrespective of time of identification...
  77. ncbi request reprint Preanalytical influences on DPC IMMULITE 2000 intact PTH assays of plasma and serum from dialysis patients
    Daniel T Holmes
    Department of Pathology and Laboratory Medicine, St Paul s Hospital, Vancouver, Canada
    Clin Chem 51:915-7. 2005
  78. ncbi request reprint Clinical epidemiology of cardiovascular disease in chronic kidney disease prior to dialysis
    Adeera Levin
    Department of Medicine, Division of Nephrology, University of British Columbia, Vancouver, Canada
    Semin Dial 16:101-5. 2003
    ..We identify the importance of well-conducted studies of patient groups with and without CVD, with and without CKD, in order to better understand the complex physiology so that treatment strategies can be appropriately applied...
  79. ncbi request reprint Vitamin D and its analogues: do they protect against cardiovascular disease in patients with kidney disease?
    Adeera Levin
    Division of Nephrology, University of British Columbia, Vancouver, Canada
    Kidney Int 68:1973-81. 2005
    ..In light of recent observational studies showing an association of vitamin D therapy and survival benefit in hemodialysis patients, the effects of vitamin D on cardiovascular system have become a heavily debated issue...