Thomas G Koch

Summary

Affiliation: University of Guelph
Country: Canada

Publications

  1. ncbi request reprint Semilobar holoprosencephaly in a Morgan horse
    Thomas G Koch
    Department of Clinical Studies, University of Guelph, Guelph, Ontario, Canada
    J Vet Intern Med 19:367-72. 2005
  2. ncbi request reprint Lymphoma, erythrocytosis, and tumor erythropoietin gene expression in a horse
    Thomas G Koch
    Department of Clinical Studies, University of Guelph, Ontario, Canada
    J Vet Intern Med 20:1251-5. 2006
  3. pmc Isolation of mesenchymal stem cells from equine umbilical cord blood
    Thomas G Koch
    Department of Biomedical Sciences, University of Guelph, Guelph, ON, Canada
    BMC Biotechnol 7:26. 2007
  4. ncbi request reprint Stem cell therapy for joint problems using the horse as a clinically relevant animal model
    Thomas G Koch
    University of Guelph, Department of Biomedical Sciences, Ontario Veterinary College, Guelph, ON, N1G 2W1, Canada
    Expert Opin Biol Ther 7:1621-6. 2007
  5. pmc Concepts for the clinical use of stem cells in equine medicine
    Thomas G Koch
    Department of Biomedical Sciences, University of Guelph, Guelph, Ontario N1G 2W1
    Can Vet J 49:1009-17. 2008
  6. pmc Current and future regenerative medicine - principles, concepts, and therapeutic use of stem cell therapy and tissue engineering in equine medicine
    Thomas G Koch
    Department of Biomedical Sciences, University of Guelph, Guelph, Ontario N1G 2W1, Canada
    Can Vet J 50:155-65. 2009
  7. doi request reprint Improved isolation protocol for equine cord blood-derived mesenchymal stromal cells
    Thomas G Koch
    Department of Biomedical Sciences, University of Guelph, Ontario, Guelph, Canada
    Cytotherapy 11:443-7. 2009
  8. doi request reprint Generation, Characterization, and Multilineage Potency of Mesenchymal-Like Progenitors Derived from Equine Induced Pluripotent Stem Cells
    Sarah I Lepage
    1 Department of Biomedical Sciences, University of Guelph, Guelph, Ontario, Canada
    Stem Cells Dev 25:80-9. 2016
  9. doi request reprint MicroRNA-140 expression during chondrogenic differentiation of equine cord blood-derived mesenchymal stromal cells
    Midori E Buechli
    Department of Biomedical Sciences, Ontario Veterinary College, University of Guelph, Guelph, Ontario, Canada
    Stem Cells Dev 22:1288-96. 2013
  10. pmc Characterization and Immunomodulatory Effects of Canine Adipose Tissue- and Bone Marrow-Derived Mesenchymal Stromal Cells
    Keith A Russell
    Departments of Biomedical Sciences, Ontario Veterinary College, University of Guelph, Guelph, Canada
    PLoS ONE 11:e0167442. 2016

Collaborators

Detail Information

Publications15

  1. ncbi request reprint Semilobar holoprosencephaly in a Morgan horse
    Thomas G Koch
    Department of Clinical Studies, University of Guelph, Guelph, Ontario, Canada
    J Vet Intern Med 19:367-72. 2005
  2. ncbi request reprint Lymphoma, erythrocytosis, and tumor erythropoietin gene expression in a horse
    Thomas G Koch
    Department of Clinical Studies, University of Guelph, Ontario, Canada
    J Vet Intern Med 20:1251-5. 2006
  3. pmc Isolation of mesenchymal stem cells from equine umbilical cord blood
    Thomas G Koch
    Department of Biomedical Sciences, University of Guelph, Guelph, ON, Canada
    BMC Biotechnol 7:26. 2007
    ..The hypothesis of this study was that equine MSCs could be isolated from fresh whole equine cord blood...
  4. ncbi request reprint Stem cell therapy for joint problems using the horse as a clinically relevant animal model
    Thomas G Koch
    University of Guelph, Department of Biomedical Sciences, Ontario Veterinary College, Guelph, ON, N1G 2W1, Canada
    Expert Opin Biol Ther 7:1621-6. 2007
    ..Equine stem cell and tissue engineering studies may be financially feasible to principal investigators and small biotechnology companies if the equine industry is successfully engaged in the research process...
  5. pmc Concepts for the clinical use of stem cells in equine medicine
    Thomas G Koch
    Department of Biomedical Sciences, University of Guelph, Guelph, Ontario N1G 2W1
    Can Vet J 49:1009-17. 2008
    ..Stem cell research in the horse has exciting equine specific and comparative perspectives that will most likely benefit the health of horses and, potentially, humans...
  6. pmc Current and future regenerative medicine - principles, concepts, and therapeutic use of stem cell therapy and tissue engineering in equine medicine
    Thomas G Koch
    Department of Biomedical Sciences, University of Guelph, Guelph, Ontario N1G 2W1, Canada
    Can Vet J 50:155-65. 2009
    ..Controlled, well-designed studies are needed to move this new equine research field forward...
  7. doi request reprint Improved isolation protocol for equine cord blood-derived mesenchymal stromal cells
    Thomas G Koch
    Department of Biomedical Sciences, University of Guelph, Ontario, Guelph, Canada
    Cytotherapy 11:443-7. 2009
    ..The objective of this study was to improve the isolation procedure for equine CB-MSCs...
  8. doi request reprint Generation, Characterization, and Multilineage Potency of Mesenchymal-Like Progenitors Derived from Equine Induced Pluripotent Stem Cells
    Sarah I Lepage
    1 Department of Biomedical Sciences, University of Guelph, Guelph, Ontario, Canada
    Stem Cells Dev 25:80-9. 2016
    ..We demonstrate a protocol for the derivation of MSC-like progenitor populations from equine iPS cells. ..
  9. doi request reprint MicroRNA-140 expression during chondrogenic differentiation of equine cord blood-derived mesenchymal stromal cells
    Midori E Buechli
    Department of Biomedical Sciences, Ontario Veterinary College, University of Guelph, Guelph, Ontario, Canada
    Stem Cells Dev 22:1288-96. 2013
    ..Together, these studies suggest that miR-140 is an important regulator of cartilage development and homeostasis in eCB-MSCs that may act, in part, through the regulation of CXCL12 and ADAMTS-5...
  10. pmc Characterization and Immunomodulatory Effects of Canine Adipose Tissue- and Bone Marrow-Derived Mesenchymal Stromal Cells
    Keith A Russell
    Departments of Biomedical Sciences, Ontario Veterinary College, University of Guelph, Guelph, Canada
    PLoS ONE 11:e0167442. 2016
    ..Little is known about the biology and function of canine MSC compared to their mouse or human counterparts. This knowledge-gap impedes development of canine evidence-based MSC technologies...
  11. pmc Response to Intravenous Allogeneic Equine Cord Blood-Derived Mesenchymal Stromal Cells Administered from Chilled or Frozen State in Serum and Protein-Free Media
    Lynn B Williams
    Department of Biomedical Sciences, University of Guelph, Guelph, ON, Canada
    Front Vet Sci 3:56. 2016
    ....
  12. pmc Larval cyathostominosis in horses in Ontario: an emerging disease?
    Andrew S Peregrine
    Department of Pathobiology, University of Guelph, Guelph, Ontario
    Can Vet J 47:80-2. 2006
    ..Cases occurred from September to May, the majority from October to December. Median age was 12 mo. Diarrhea, colic, and weight loss were common clinical signs. Hypoalbuminemia and microcytosis were consistent findings...
  13. pmc Aspiration, but not injection, decreases cultured equine mesenchymal stromal cell viability
    Lynn B Williams
    Department of Clinical Studies, Ontario Veterinary College, University of Guelph, Guelph, Ontario, Canada
    BMC Vet Res 12:45. 2016
    ..We hypothesize that viability of equine MSC is not correlated with needle diameter during aspiration and injection...
  14. pmc Phenotypic and immunomodulatory properties of equine cord blood-derived mesenchymal stromal cells
    Laurence Tessier
    Department of Biomedical Sciences, Ontario Veterinary College, University of Guelph, Guelph, Canada
    PLoS ONE 10:e0122954. 2015
    ..The relationship between TLRs and lymphocyte function warrants further investigation. ..
  15. ncbi request reprint Use of somatic cell nuclear transfer to study meiosis in female cattle carrying a sex-dependent fertility-impairing X-chromosome abnormality
    Gyu Jin Rho
    Department of Biomedical Science, University of Guelph, Guelph, Ontario, Canada
    Cloning Stem Cells 9:118-29. 2007
    ....