Dong Dong

Summary

Affiliation: University of Toronto
Country: Canada

Publications

  1. pmc Dynamic evolution of bitter taste receptor genes in vertebrates
    Dong Dong
    School of Life Sciences, East China Normal University, Shanghai, PR China
    BMC Evol Biol 9:12. 2009
  2. pmc Gene expression variations are predictive for stochastic noise
    Dong Dong
    Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, Toronto, ON, Canada
    Nucleic Acids Res 39:403-13. 2011
  3. pmc Evidences for increased expression variation of duplicate genes in budding yeast: from cis- to trans-regulation effects
    Dong Dong
    Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, 160 College Street, Toronto, ON, M5S 3E1, Canada
    Nucleic Acids Res 39:837-47. 2011
  4. doi request reprint Differential effects of chromatin regulators and transcription factors on gene regulation: a nucleosomal perspective
    Dong Dong
    Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, Toronto, ON, Canada
    Bioinformatics 27:147-52. 2011
  5. pmc Preferential regulation of stably expressed genes in the human genome suggests a widespread expression buffering role of microRNAs
    Zhen Yang
    School of Life Sciences, Fudan University, Shanghai, 200433, China
    BMC Genomics 13:S14. 2012
  6. doi request reprint Understanding the combinatorial action of transcription factors and microRNA regulation from regions of open chromatin
    Guantao Zheng
    Laboratory of Molecular Ecology and Evolution, Institute of Estuarine and Coastal Research, East China Normal University, Shanghai, 200062, P R China
    Mol Biosyst 12:371-8. 2016
  7. doi request reprint The Genomes of Two Bat Species with Long Constant Frequency Echolocation Calls
    Dong Dong
    Shanghai Key Laboratory of Regulatory Biology, Institute of Biomedical Sciences, School of Life Sciences, East China Normal University, Shanghai, China
    Mol Biol Evol . 2016
  8. pmc CRDB: database of chemosensory receptor gene families in vertebrate
    Dong Dong
    Institute of Molecular Ecology and Evolution, iAIR, East China Normal University, Shanghai, China
    PLoS ONE 7:e31540. 2012
  9. doi request reprint Evolution of an X-linked primate-specific micro RNA cluster
    Jingjing Li
    Department of Molecular Genetics, University of Toronto, Toronto, ON, Canada
    Mol Biol Evol 27:671-83. 2010
  10. doi request reprint Positive selection drives the evolution of bat bitter taste receptor genes
    Yingying Zhou
    School of Life Science, East China Normal University, Shanghai, People s Republic of China
    Biochem Genet 47:207-15. 2009

Collaborators

Detail Information

Publications20

  1. pmc Dynamic evolution of bitter taste receptor genes in vertebrates
    Dong Dong
    School of Life Sciences, East China Normal University, Shanghai, PR China
    BMC Evol Biol 9:12. 2009
    ..Previous studies have identified some T2R gene repertoires, and marked variation in repertoire size has been noted among species. However, the mechanisms underlying the evolution of vertebrate T2R genes remain poorly understood...
  2. pmc Gene expression variations are predictive for stochastic noise
    Dong Dong
    Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, Toronto, ON, Canada
    Nucleic Acids Res 39:403-13. 2011
    ..g. chromatin regulation. Our work paves the way for the study of stochastic noise in other single-cell organisms...
  3. pmc Evidences for increased expression variation of duplicate genes in budding yeast: from cis- to trans-regulation effects
    Dong Dong
    Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, 160 College Street, Toronto, ON, M5S 3E1, Canada
    Nucleic Acids Res 39:837-47. 2011
    ....
  4. doi request reprint Differential effects of chromatin regulators and transcription factors on gene regulation: a nucleosomal perspective
    Dong Dong
    Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, Toronto, ON, Canada
    Bioinformatics 27:147-52. 2011
    ..In this article we attempted to address this problem and examine the patterns of CR and TF regulation effects from the nucleosome perspective...
  5. pmc Preferential regulation of stably expressed genes in the human genome suggests a widespread expression buffering role of microRNAs
    Zhen Yang
    School of Life Sciences, Fudan University, Shanghai, 200433, China
    BMC Genomics 13:S14. 2012
    ..Evidence suggests that miRNAs can constrain the variation of their target to buffer the fluctuation of expression. However, whether this effect can act on the genome-wide expression remains controversial...
  6. doi request reprint Understanding the combinatorial action of transcription factors and microRNA regulation from regions of open chromatin
    Guantao Zheng
    Laboratory of Molecular Ecology and Evolution, Institute of Estuarine and Coastal Research, East China Normal University, Shanghai, 200062, P R China
    Mol Biosyst 12:371-8. 2016
    ..Our results provide us a clue that the coordinated activity of miRNAs and TFs describing the mechanism of gene expression control should be examined in a dynamic perspective. ..
  7. doi request reprint The Genomes of Two Bat Species with Long Constant Frequency Echolocation Calls
    Dong Dong
    Shanghai Key Laboratory of Regulatory Biology, Institute of Biomedical Sciences, School of Life Sciences, East China Normal University, Shanghai, China
    Mol Biol Evol . 2016
    ..Moreover, evidence of genetic adaptations to high altitudes in the great leaf-nosed bats was observed. Taken together, our work provided a useful resource for future research on the evolution of bats...
  8. pmc CRDB: database of chemosensory receptor gene families in vertebrate
    Dong Dong
    Institute of Molecular Ecology and Evolution, iAIR, East China Normal University, Shanghai, China
    PLoS ONE 7:e31540. 2012
    ..Our work can provide a rigorous platform for further study on the evolution of CR genes in vertebrates...
  9. doi request reprint Evolution of an X-linked primate-specific micro RNA cluster
    Jingjing Li
    Department of Molecular Genetics, University of Toronto, Toronto, ON, Canada
    Mol Biol Evol 27:671-83. 2010
    ..Collectively, we argue these miRNAs might play an important role in epididymal morphogenesis and sperm maturation and in establishing primate-specific epididymal characteristics...
  10. doi request reprint Positive selection drives the evolution of bat bitter taste receptor genes
    Yingying Zhou
    School of Life Science, East China Normal University, Shanghai, People s Republic of China
    Biochem Genet 47:207-15. 2009
    ....
  11. pmc Systematic analyses and comprehensive field synopsis of genetic association studies in hepatocellular carcinoma
    Dong Dong
    Laboratory of Molecular Ecology and Evolution, Institute of Estuarine and Coastal Research, East China Normal University, Shanghai, 200062, P R China
    Oncotarget 7:45757-45763. 2016
    ..We have provided a useful resource and platform for investigators to explore the association of sequence polymorphisms and HCC risk...
  12. pmc BGD: a database of bat genomes
    Jianfei Fang
    Institute of Molecular Ecology and Evolution, SKLEC and IECR, East China Normal University, Shanghai, China
    PLoS ONE 10:e0131296. 2015
    ..It will extend our understanding of the bat evolution and be advantageous to the bat sequences analysis. BGD is freely available at: http://donglab.ecnu.edu.cn/databases/BatGenome/. ..
  13. pmc Comparative inner ear transcriptome analysis between the Rickett's big-footed bats (Myotis ricketti) and the greater short-nosed fruit bats (Cynopterus sphinx)
    Dong Dong
    Institute for Advanced Interdisciplinary Research in Science and Technology, East China Normal University, Shanghai, China
    BMC Genomics 14:916. 2013
    ..Bats have aroused great interests of researchers for the sake of their advanced echolocation system. However, this highly specialized trait is not characteristic of Old World fruit bats...
  14. pmc Comparison of brain transcriptome of the greater horseshoe bats (Rhinolophus ferrumequinum) in active and torpid episodes
    Ming Lei
    Institute of Molecular Ecology and Evolution, SKLEC and IECR, East China Normal University, Shanghai, China
    PLoS ONE 9:e107746. 2014
    ....
  15. pmc Adaptation of peroxisome proliferator-activated receptor alpha to hibernation in bats
    Yijie Han
    Laboratory of Molecular Ecology and Evolution, Institute for Advanced Studies in Multidisciplinary Science and Technology, East China Normal University, Shanghai, 200062, China
    BMC Evol Biol 15:88. 2015
    ..The role of PPARĪ± in hibernation of mammals remains largely unknown. Using a multidisciplinary approach, we investigated whether PPARĪ± is adapted to hibernation in bats...
  16. pmc Digital gene expression tag profiling of bat digits provides robust candidates contributing to wing formation
    Zhe Wang
    Institute of Molecular Ecology and Evolution, iAIR, East China Normal University, Shanghai 200062, PR China
    BMC Genomics 11:619. 2010
    ....
  17. pmc DAnCER: disease-annotated chromatin epigenetics resource
    Andrei L Turinsky
    Hospital for Sick Children, Banting and Best Department of Medical Research, University of Toronto, Toronto, Ontario, Canada
    Nucleic Acids Res 39:D889-94. 2011
    ..DAnCER is freely available at http://wodaklab.org/dancer/...
  18. pmc Evolution of Olfactory Receptor Genes in Primates Dominated by Birth-and-Death Process
    Dong Dong
    Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, Toronto, Ontario, Canada
    Genome Biol Evol 2009:258-64. 2009
    ..Differential selective constraints might play important role in the primate OR gene evolution in each primate species...
  19. pmc Phylogenomic analyses of bat subordinal relationships based on transcriptome data
    Ming Lei
    Laboratory of Molecular Ecology and Evolution, Institute of Estuarine and Coastal Research, East China Normal University, Shanghai, 200062, China
    Sci Rep 6:27726. 2016
    ..Our work provided a valuable resource to further explore the evolutionary relationship within bats. ..
  20. doi request reprint Molecular cloning and evolutionary analysis of hemoglobin alpha-chain genes in bats
    Yang Liu
    School of Life Science, East China Normal University, Shanghai, People s Republic of China
    Biochem Genet 47:257-65. 2009
    ..These codons are under divergent selection in bats. These changes in Hb may have occurred in response to the physiological requirements of the species concerned, as adaptations to different lifestyles...