Douglas Coyle

Summary

Affiliation: University of Ottawa
Country: Canada

Publications

  1. ncbi request reprint Effects of aerobic training, resistance training, or both on glycemic control in type 2 diabetes: a randomized trial
    Ronald J Sigal
    University of Ottawa, Clinical Epidemiology Program, Ottawa Health Research Institute, and Prevention and Rehabilitation Centre, University of Ottawa Heart Institute, Ottawa, Ontario, Canada
    Ann Intern Med 147:357-69. 2007
  2. doi request reprint Effect of exercise training on physical fitness in type II diabetes mellitus
    Joanie Larose
    University of Ottawa, Ontario, Canada
    Med Sci Sports Exerc 42:1439-47. 2010
  3. doi request reprint Opportunity cost of funding drugs for rare diseases: the cost-effectiveness of eculizumab in paroxysmal nocturnal hemoglobinuria
    Doug Coyle
    Department of Epidemiology and Community Medicine, University of Ottawa, Ottawa, Canada DC Division of Hematology Oncology, Sunnybrook Health Sciences Centre, Odette Cancer Center, University of Toronto, Toronto, ON, Canada MCC Division of Infectious Diseases, Department of Medicine, Kingston General Hospital and Queen s University, Kingston, ON, Canada GAE
    Med Decis Making 34:1016-29. 2014
  4. pmc Routine versus selective cardiac magnetic resonance in non-ischemic heart failure - OUTSMART-HF: study protocol for a randomized controlled trial (IMAGE-HF (heart failure) project 1-B)
    Ian Paterson
    Mazankowski Alberta Heart Institute, University of Alberta, Edmonton, AB, Canada
    Trials 14:332. 2013
  5. pmc Computed tomographic coronary angiography for patients with heart failure (CTA-HF): a randomized controlled trial (IMAGE HF Project 1-C)
    Benjamin J W Chow
    Department of Medicine, Division of Cardiology, including Cardiac Imaging, The Heart Failure Program, and the Cardiac ResearchMethods Centre, University of Ottawa Heart Institute, 40 Ruskin Street, Ottawa, ON K1Y 4W7, Canada
    Trials 14:443. 2013
  6. pmc Alternative Imaging Modalities in Ischemic Heart Failure (AIMI-HF) IMAGE HF Project I-A: study protocol for a randomized controlled trial
    Eileen O'Meara
    Montreal Heart Institute, Montreal, QC, Canada
    Trials 14:218. 2013
  7. doi request reprint Cost-effectiveness of exercise programs in type 2 diabetes
    Doug Coyle
    University of Ottawa, Ontario, Canada
    Int J Technol Assess Health Care 28:228-34. 2012
  8. pmc Comparing multiple competing interventions in the absence of randomized trials using clinical risk-benefit analysis
    Alejandro Lazo-Langner
    Department of Medicine, University of Western Ontario, London ON, Canada
    BMC Med Res Methodol 12:3. 2012
  9. pmc Determining utility values related to malaria and malaria chemoprophylaxis
    Anne E McCarthy
    Tropical Medicine and International Health Clinic, Division of Infectious Diseases Ottawa Hospital General Campus, University of Ottawa, 501 Smyth Road, Ottawa, Ontario K1H 8L6, Canada
    Malar J 9:92. 2010
  10. ncbi request reprint Cost-effectiveness of irbesartan 300 mg given early versus late in patients with hypertension and a history of type 2 diabetes and renal disease: a Canadian perspective
    Douglas Coyle
    Department of Epidemiology and Community Medicine, University of Ottawa, Ottawa, Ontario, Canada
    Clin Ther 29:1508-23. 2007

Collaborators

Detail Information

Publications36

  1. ncbi request reprint Effects of aerobic training, resistance training, or both on glycemic control in type 2 diabetes: a randomized trial
    Ronald J Sigal
    University of Ottawa, Clinical Epidemiology Program, Ottawa Health Research Institute, and Prevention and Rehabilitation Centre, University of Ottawa Heart Institute, Ottawa, Ontario, Canada
    Ann Intern Med 147:357-69. 2007
    ..However, none could assess incremental effects of combined aerobic and resistance training compared with either type of exercise alone...
  2. doi request reprint Effect of exercise training on physical fitness in type II diabetes mellitus
    Joanie Larose
    University of Ottawa, Ontario, Canada
    Med Sci Sports Exerc 42:1439-47. 2010
    ..In addition, no study to date has compared strength gains between resistance training and combined exercise training in type II diabetes mellitus (T2DM)...
  3. doi request reprint Opportunity cost of funding drugs for rare diseases: the cost-effectiveness of eculizumab in paroxysmal nocturnal hemoglobinuria
    Doug Coyle
    Department of Epidemiology and Community Medicine, University of Ottawa, Ottawa, Canada DC Division of Hematology Oncology, Sunnybrook Health Sciences Centre, Odette Cancer Center, University of Toronto, Toronto, ON, Canada MCC Division of Infectious Diseases, Department of Medicine, Kingston General Hospital and Queen s University, Kingston, ON, Canada GAE
    Med Decis Making 34:1016-29. 2014
    ..This article reports both the cost-effectiveness of eculizumab for the treatment of paroxysmal nocturnal hemoglobinuria (PNH) and its associated opportunity costs...
  4. pmc Routine versus selective cardiac magnetic resonance in non-ischemic heart failure - OUTSMART-HF: study protocol for a randomized controlled trial (IMAGE-HF (heart failure) project 1-B)
    Ian Paterson
    Mazankowski Alberta Heart Institute, University of Alberta, Edmonton, AB, Canada
    Trials 14:332. 2013
    ..This will lead to a reduction in the non-specific diagnoses of idiopathic dilated cardiomyopathy and HF with preserved ejection fraction...
  5. pmc Computed tomographic coronary angiography for patients with heart failure (CTA-HF): a randomized controlled trial (IMAGE HF Project 1-C)
    Benjamin J W Chow
    Department of Medicine, Division of Cardiology, including Cardiac Imaging, The Heart Failure Program, and the Cardiac ResearchMethods Centre, University of Ottawa Heart Institute, 40 Ruskin Street, Ottawa, ON K1Y 4W7, Canada
    Trials 14:443. 2013
    ..Acknowledging the aging population, the growing prevalence of HF and the increasing financial burden of healthcare, we need to identify non-invasive diagnostic tests that are available, safe, accurate and cost-effective...
  6. pmc Alternative Imaging Modalities in Ischemic Heart Failure (AIMI-HF) IMAGE HF Project I-A: study protocol for a randomized controlled trial
    Eileen O'Meara
    Montreal Heart Institute, Montreal, QC, Canada
    Trials 14:218. 2013
    ....
  7. doi request reprint Cost-effectiveness of exercise programs in type 2 diabetes
    Doug Coyle
    University of Ottawa, Ontario, Canada
    Int J Technol Assess Health Care 28:228-34. 2012
    ..However, these programs are associated with additional costs. This analysis assessed the cost-effectiveness of such programs...
  8. pmc Comparing multiple competing interventions in the absence of randomized trials using clinical risk-benefit analysis
    Alejandro Lazo-Langner
    Department of Medicine, University of Western Ontario, London ON, Canada
    BMC Med Res Methodol 12:3. 2012
    ....
  9. pmc Determining utility values related to malaria and malaria chemoprophylaxis
    Anne E McCarthy
    Tropical Medicine and International Health Clinic, Division of Infectious Diseases Ottawa Hospital General Campus, University of Ottawa, 501 Smyth Road, Ottawa, Ontario K1H 8L6, Canada
    Malar J 9:92. 2010
    ..Such models require utility values reflecting societal preferences over different health states of relevance. To date, there are no published utility values relating to clinical malaria or chemoprophylaxis adverse events...
  10. ncbi request reprint Cost-effectiveness of irbesartan 300 mg given early versus late in patients with hypertension and a history of type 2 diabetes and renal disease: a Canadian perspective
    Douglas Coyle
    Department of Epidemiology and Community Medicine, University of Ottawa, Ottawa, Ontario, Canada
    Clin Ther 29:1508-23. 2007
    ..The Irbesartan in Reduction of Microalbuminuria trial and the Irbesartan in Diabetic Nephropathy Trial found that irbesartan is renoprotective in patients having hypertension with type 2 diabetes...
  11. ncbi request reprint Estimating the expected value of partial perfect information: a review of methods
    Doug Coyle
    Department of Epidemiology and Community Medicine, University of Ottawa, 451 Smyth Road, Ottawa, ON, Canada, K1H 8M5
    Eur J Health Econ 9:251-9. 2008
    ..The mathematical definition of the expected value of perfect information (EVPI) is fixed, though there are different methods in the literature for its estimation. In this paper these methods are explored and compared...
  12. ncbi request reprint Economic evaluation of the use of irbesartan and amlodipine in the treatment of diabetic nephropathy in patients with hypertension in Canada
    Douglas Coyle
    Ottawa Health Research Institute, Ottawa Hospital, Ottawa, Ontario, Canada
    Can J Cardiol 20:71-9. 2004
    ....
  13. ncbi request reprint Economic evaluation of pioglitazone hydrochloride in the management of type 2 diabetes mellitus in Canada
    Douglas Coyle
    Departments of Medicine and Epidemiology, and Community Medicine, University of Ottawa Clinical Epidemiology, Ottawa Health Research Institute, Ottawa Hospital Ottawa, Ontario, Canada
    Pharmacoeconomics 20:31-42. 2002
    ..Given the results of these trials, we assessed the cost effectiveness of the use of pioglitazone as a first-line therapy in Canada...
  14. ncbi request reprint Measures of importance for economic analysis based on decision modeling
    Douglas Coyle
    Clinical Epidemiology Program, Ottawa Health Research Institute, 1053 Carling Avenue, Ottawa, ON K1Y 4E9, Canada
    J Clin Epidemiol 56:989-97. 2003
    ..A selection of the most commonly used measures were applied to an economic model of treatment for patients with Parkinson's disease. Techniques were evaluated in terms of their ranking of variables, complexity, and interpretation...
  15. ncbi request reprint Who's better not best: appropriate probabilistic uncertainty analysis
    Douglas Coyle
    Clinical Epidemiology Unit, Ottawa Health Research Institute, Ottawa Hospital, Ontario, Canada
    Int J Technol Assess Health Care 19:540-5. 2003
    ..This study highlights three specific points for concern and offers constructive criticism by recommending more appropriate approaches...
  16. ncbi request reprint Which cancer clinical trials should be considered for economic evaluation? Selection criteria from the National Cancer Institute of Canada's Working Group on Economic Analysis
    William K Evans
    Cancer Care Ontario, 620 University Avenue, Toronto, Ontario, Canada M5G 2L7
    Chronic Dis Can 24:102-7. 2003
    ..These recommendations are currently guiding priority setting with regard to trials for economic evaluation in NCIC trials. Examples of how these recommendations have been applied to actual trials are presented...
  17. doi request reprint Ottawa panel evidence-based clinical practice guidelines for aerobic walking programs in the management of osteoarthritis
    Laurianne Loew
    School of Rehabilitation Sciences, Faculty of Health Sciences, University of Ottawa, Ontario, Canada
    Arch Phys Med Rehabil 93:1269-85. 2012
    ..To update the Evidence-Based Clinical Practice Guidelines (EBCPGs) on aerobic walking programs for the management of osteoarthritis (OA) of the knee...
  18. ncbi request reprint Impact of program duration and contact frequency on efficacy and cost of cardiac rehabilitation: results of a randomized trial
    Robert D Reid
    Prevention and Rehabilitation Centre, University of Ottawa Heart Institute, Ottawa, Ontario, Canada
    Am Heart J 149:862-8. 2005
    ....
  19. ncbi request reprint Application of the 1998 Canadian cholesterol guidelines to a military population: health benefits and cost effectiveness of improved cholesterol management
    Johanna N Spaans
    Department of Epidemiology and Community Medicine, University of Ottawa, Ottawa, Canada
    Can J Cardiol 19:790-6. 2003
    ..To determine whether statins are underprescribed in the Canadian military. The cost effectiveness of statin therapy in patients identified by the 1998 Canadian cholesterol interim guidelines was also explored...
  20. ncbi request reprint Impact of particulate air pollution on quality-adjusted life expectancy in Canada
    Douglas Coyle
    Ottawa Health Research Institute, University of Ottawa, Ottawa, Ontario, Canada
    J Toxicol Environ Health A 66:1847-63. 2003
    ..Further analysis can assess the efficiency of targeting such initiatives to communities that are most likely to benefit...
  21. doi request reprint Effectiveness of a hospital-initiated smoking cessation programme: 2-year health and healthcare outcomes
    Kerri A Mullen
    University of Ottawa Heart Institute, Ottawa, Ontario, Canada
    Tob Control . 2016
    ..Tobacco-related illnesses are leading causes of death and healthcare use. Our objective was to determine whether implementation of a hospital-initiated smoking cessation intervention would reduce mortality and downstream healthcare usage...
  22. doi request reprint Estimating quality of life in acute venous thrombosis
    Kerstin Hogg
    Department of Medicine, University of Ottawa, Ottawa, Ontario, Canada
    JAMA Intern Med 173:1067-72. 2013
    ..Future funding for new treatments in venous thromboembolism will be guided by cost-utility analyses. There is little available information on the utility of acute venous thromboembolism, limiting the validity of economic analyses...
  23. ncbi request reprint Economic evaluation of norethisterone acetate/ethinylestradiol (FemHRT) for women with menopausal symptoms
    Douglas Coyle
    Clinical Epidemiology, Ottawa Health Research Institute, Ottawa Hospital Department of Medicine and Epidemiology, University of Ottawa, Ottawa, Ontario, Canada
    Pharmacoeconomics 21:661-9. 2003
    ....
  24. ncbi request reprint Towards a reference case for economic evaluation of osteoporosis treatments
    Douglas Coyle
    Faculty of Medicine, University of Ottawa, and the Clinical Epidemiology Program, Ottawa Health Research Institute, Ottawa Hospital, Ottawa, Canada
    J Rheumatol Suppl 68:31-6. 2003
  25. ncbi request reprint Stratified cost-effectiveness analysis: a framework for establishing efficient limited use criteria
    Douglas Coyle
    Department of Medicine, University of Ottawa, and Ottawa Health Research Institute, Ottawa, ON, Canada
    Health Econ 12:421-7. 2003
    ....
  26. doi request reprint Validity of standard gamble estimated quality of life in acute venous thrombosis
    Kerstin Hogg
    Ottawa Hospital Research Institute, 1053 Carling Avenue, E Main, EM 206, Box 227, Ottawa, ON, K1Y 4E9, Canada Electronic address
    Thromb Res 134:819-25. 2014
    ..The current study aimed to explore the reasons for variability by comparing the standard gamble technique in patients with acute venous thrombosis to other quality of life measurement tools...
  27. pmc (Correcting) misdiagnoses of asthma: a cost effectiveness analysis
    Smita Pakhale
    University of Ottawa, and The Ottawa Hospital Research Institute, Ottawa, ON K1H 8L6, Canada
    BMC Pulm Med 11:27. 2011
    ..The prevalence of physician-diagnosed-asthma has risen over the past three decades and misdiagnosis of asthma is potentially common...
  28. ncbi request reprint Determining the optimal combinations of mutually exclusive interventions: a response to Hutubessy and colleagues
    Douglas Coyle
    Clinical Epidemiology Unit, Ottawa Health Research Institute, Ottawa, Canada
    Health Econ 12:159-62; discussion 163-4. 2003
    ..A simple alternative approach is suggested which avoids these problems...
  29. ncbi request reprint Economic burden of hepatitis C in Canada and the potential impact of prevention. Results from a disease model
    Susie El Saadany
    Centre for Infectious Disease Prevention and Control, Public Health Agency of Canada, Ottawa, Ont, Canada
    Eur J Health Econ 6:159-65. 2005
    ..6 million for prevention. The increasing cost of HCV provides a framework for further analysis and implementation of long-term policies aimed at appropriate allocation of resources for health in Canada...
  30. ncbi request reprint Cost effectiveness of Elidel in the management of patients with atopic dermatitis in Canada
    Douglas Coyle
    Ottawa Health Research Institute, Ottawa Hospital, Ottawa, Ontario, Canada
    J Cutan Med Surg 8:405-10. 2004
    ..With increasing pressure on health care resources, it is necessary to demonstrate that new treatments are both effective and cost effective...
  31. pmc Economic evaluation of a hospital-initiated intervention for smokers with chronic disease, in Ontario, Canada
    Kerri Anne Mullen
    Division of Prevention and Rehabilitation, University of Ottawa Heart Institute, Ottawa, Ontario, Canada
    Tob Control 24:489-96. 2015
    ....
  32. doi request reprint Evaluating survivorship care plans: results of a randomized, clinical trial of patients with breast cancer
    Eva Grunfeld
    Ontario Institute for Cancer Research, Ontario, Canada
    J Clin Oncol 29:4755-62. 2011
    ..An Institute of Medicine report recommends that patients with cancer receive a survivorship care plan (SCP). The trial objective was to determine if an SCP for breast cancer survivors improves patient-reported outcomes...
  33. ncbi request reprint The role of models within economic analysis: focus on type 2 diabetes mellitus
    Douglas Coyle
    Departments of Medicine and Epidemiology, and Community Medicine, University of Ottawa Clinical Epidemiology, Ottawa Health Research Institute, Ottawa Hospital Ottawa, Ontario, Canada
    Pharmacoeconomics 20:11-9. 2002
    ..The value of such further information must be weighed against the costs of its acquisition...
  34. ncbi request reprint Prospective evaluation of preferences and quality of life in women with hip fractures
    Ann B Cranney
    Ottawa Health Research Institute, Ottawa, Canada
    J Rheumatol 32:2393-9. 2005
    ..We also compared HRQOL in women with recent hip fractures to a control sample at baseline and to normative Canadian data at followup...
  35. doi request reprint Cost-effectiveness of epinephrine and dexamethasone in children with bronchiolitis
    Amanda Sumner
    Clinical Research Unit, Children s Hospital of Eastern Ontario Research Institute, and Department of Epidemiology and Community Medicine, University of Ottawa, 401 Smyth Ave, Ottawa, Ontario, Canada K1H 8L1
    Pediatrics 126:623-31. 2010
    ..Using data from the Canadian Bronchiolitis Epinephrine Steroid Trial we assessed the cost-effectiveness of treatments with epinephrine and dexamethasone for infants between 6 weeks and 12 months of age with bronchiolitis...
  36. doi request reprint Wage losses in the year after breast cancer: extent and determinants among Canadian women
    Sophie Lauzier
    Unité de recherche en santé des populations, Centre de Recherche du Centre Hospitalier affilié universitaire de Québec, Quebec, Canada
    J Natl Cancer Inst 100:321-32. 2008
    ..We evaluated wage losses, their determinants, and the associations between wage losses and changes for the worse in the family's financial situation among Canadian women over the first 12 months after diagnosis of early breast cancer...