Benjamin J W Chow

Summary

Affiliation: University of Ottawa Heart Institute
Country: Canada

Publications

  1. ncbi request reprint Systemic and inflammatory disorders involving the heart: the role of PET imaging
    Daniel Juneau
    Division of Cardiology, Department of Medicine, University of Ottawa Heart Institute, Ottawa, Canada
    Q J Nucl Med Mol Imaging 60:383-96. 2016
  2. pmc Routine versus selective cardiac magnetic resonance in non-ischemic heart failure - OUTSMART-HF: study protocol for a randomized controlled trial (IMAGE-HF (heart failure) project 1-B)
    Ian Paterson
    Mazankowski Alberta Heart Institute, University of Alberta, Edmonton, AB, Canada
    Trials 14:332. 2013
  3. pmc Does intravenous contrast-enhanced computed tomography cause acute kidney injury? Protocol of a systematic review of the evidence
    Jeanne Françoise Kayibanda
    Division of Nephrology, Faculty of Medicine, University of Ottawa, Ottawa, Ontario K1N 6N5, Canada
    Syst Rev 3:94. 2014
  4. doi request reprint Prognostic value of PET myocardial perfusion imaging in obese patients
    Benjamin J W Chow
    Department of Medicine Cardiology, University of Ottawa Heart Institute, Ottawa, Ontario, Canada Department of Radiology, University of Ottawa, Ottawa, Ontario, Canada Electronic address
    JACC Cardiovasc Imaging 7:278-87. 2014
  5. pmc Computed tomographic coronary angiography for patients with heart failure (CTA-HF): a randomized controlled trial (IMAGE HF Project 1-C)
    Benjamin J W Chow
    Department of Medicine, Division of Cardiology, including Cardiac Imaging, The Heart Failure Program, and the Cardiac ResearchMethods Centre, University of Ottawa Heart Institute, 40 Ruskin Street, Ottawa, ON K1Y 4W7, Canada
    Trials 14:443. 2013
  6. pmc Alternative Imaging Modalities in Ischemic Heart Failure (AIMI-HF) IMAGE HF Project I-A: study protocol for a randomized controlled trial
    Eileen O'Meara
    Montreal Heart Institute, Montreal, QC, Canada
    Trials 14:218. 2013
  7. pmc Individual patient data meta-analysis for the clinical assessment of coronary computed tomography angiography: protocol of the Collaborative Meta-Analysis of Cardiac CT (CoMe-CCT)
    Georg M Schuetz
    Department of Radiology, Charité Universitätsmedizin Berlin Campus Mitte, Humboldt Universitat zu Berlin, Freie Universitat Berlin, Chariteplatz 1, Berlin 10117, Germany
    Syst Rev 2:13. 2013
  8. ncbi request reprint Prognostication of cardiac CT angiography
    N Gauthier
    Division of Cardiology, University of Ottawa Heart Institute, Ottawa, ON, Canada
    Minerva Cardioangiol 60:331-46. 2012
  9. doi request reprint Incremental prognostic value of cardiac computed tomography in coronary artery disease using CONFIRM: COroNary computed tomography angiography evaluation for clinical outcomes: an InteRnational Multicenter registry
    Benjamin J W Chow
    Department of Medicine Cardiology, University of Ottawa Heart Institute, Ontario, Canada
    Circ Cardiovasc Imaging 4:463-72. 2011
  10. doi request reprint Can differences in corrected coronary opacification measured with computed tomography predict resting coronary artery flow?
    Benjamin J W Chow
    Division of Cardiology, University of Ottawa Heart Institute, Ottawa, Ontario, Canada
    J Am Coll Cardiol 57:1280-8. 2011

Detail Information

Publications80

  1. ncbi request reprint Systemic and inflammatory disorders involving the heart: the role of PET imaging
    Daniel Juneau
    Division of Cardiology, Department of Medicine, University of Ottawa Heart Institute, Ottawa, Canada
    Q J Nucl Med Mol Imaging 60:383-96. 2016
    ..PET appears to be particularly useful in cases where standard investigation is non-diagnostic or equivocal. ..
  2. pmc Routine versus selective cardiac magnetic resonance in non-ischemic heart failure - OUTSMART-HF: study protocol for a randomized controlled trial (IMAGE-HF (heart failure) project 1-B)
    Ian Paterson
    Mazankowski Alberta Heart Institute, University of Alberta, Edmonton, AB, Canada
    Trials 14:332. 2013
    ..This will lead to a reduction in the non-specific diagnoses of idiopathic dilated cardiomyopathy and HF with preserved ejection fraction...
  3. pmc Does intravenous contrast-enhanced computed tomography cause acute kidney injury? Protocol of a systematic review of the evidence
    Jeanne Françoise Kayibanda
    Division of Nephrology, Faculty of Medicine, University of Ottawa, Ottawa, Ontario K1N 6N5, Canada
    Syst Rev 3:94. 2014
    ..e. death, hospitalization and need for renal replacement therapy) due to IV contrast-enhanced CT scans...
  4. doi request reprint Prognostic value of PET myocardial perfusion imaging in obese patients
    Benjamin J W Chow
    Department of Medicine Cardiology, University of Ottawa Heart Institute, Ottawa, Ontario, Canada Department of Radiology, University of Ottawa, Ottawa, Ontario, Canada Electronic address
    JACC Cardiovasc Imaging 7:278-87. 2014
    ..This study sought to determine and compare the prognostic and incremental value of positron emission tomography (PET) in normal, overweight, and obese patients...
  5. pmc Computed tomographic coronary angiography for patients with heart failure (CTA-HF): a randomized controlled trial (IMAGE HF Project 1-C)
    Benjamin J W Chow
    Department of Medicine, Division of Cardiology, including Cardiac Imaging, The Heart Failure Program, and the Cardiac ResearchMethods Centre, University of Ottawa Heart Institute, 40 Ruskin Street, Ottawa, ON K1Y 4W7, Canada
    Trials 14:443. 2013
    ..Acknowledging the aging population, the growing prevalence of HF and the increasing financial burden of healthcare, we need to identify non-invasive diagnostic tests that are available, safe, accurate and cost-effective...
  6. pmc Alternative Imaging Modalities in Ischemic Heart Failure (AIMI-HF) IMAGE HF Project I-A: study protocol for a randomized controlled trial
    Eileen O'Meara
    Montreal Heart Institute, Montreal, QC, Canada
    Trials 14:218. 2013
    ....
  7. pmc Individual patient data meta-analysis for the clinical assessment of coronary computed tomography angiography: protocol of the Collaborative Meta-Analysis of Cardiac CT (CoMe-CCT)
    Georg M Schuetz
    Department of Radiology, Charité Universitätsmedizin Berlin Campus Mitte, Humboldt Universitat zu Berlin, Freie Universitat Berlin, Chariteplatz 1, Berlin 10117, Germany
    Syst Rev 2:13. 2013
    ..The individual patient data meta-analysis is registered with the PROSPERO database (CoMe-CCT, CRD42012002780)...
  8. ncbi request reprint Prognostication of cardiac CT angiography
    N Gauthier
    Division of Cardiology, University of Ottawa Heart Institute, Ottawa, ON, Canada
    Minerva Cardioangiol 60:331-46. 2012
    ....
  9. doi request reprint Incremental prognostic value of cardiac computed tomography in coronary artery disease using CONFIRM: COroNary computed tomography angiography evaluation for clinical outcomes: an InteRnational Multicenter registry
    Benjamin J W Chow
    Department of Medicine Cardiology, University of Ottawa Heart Institute, Ontario, Canada
    Circ Cardiovasc Imaging 4:463-72. 2011
    ..We sought to confirm the independent and incremental prognostic value of coronary artery disease (CAD) severity measured using 64-slice CCTA over LVEF and clinical variables...
  10. doi request reprint Can differences in corrected coronary opacification measured with computed tomography predict resting coronary artery flow?
    Benjamin J W Chow
    Division of Cardiology, University of Ottawa Heart Institute, Ottawa, Ontario, Canada
    J Am Coll Cardiol 57:1280-8. 2011
    ..A proof-of-concept study was undertaken to determine whether differences in corrected coronary opacification (CCO) within coronary lumen can identify arteries with abnormal resting coronary flow...
  11. doi request reprint Prognostic value of CT angiography in coronary bypass patients
    Benjamin J W Chow
    Division of Cardiology, University of Ottawa Heart Institute, Ottawa, Ontario, Canada
    JACC Cardiovasc Imaging 4:496-502. 2011
    ..We sought the incremental prognostic value of coronary computed tomography angiography (CTA) in coronary artery bypass graft (CABG) patients...
  12. doi request reprint Usefulness of computed tomographic coronary angiography in patients with acute chest pain with and without high-risk features
    Benjamin J W Chow
    Department of Medicine, University of Ottawa Heart Institute, Ottawa, Ontario, Canada
    Am J Cardiol 106:463-9. 2010
    ..97). In conclusion, CTA might represent a single modality that could be used to triage a wide spectrum of patients with ACPS and could have the potential to rule out coronary disease and identify those who might require revascularization...
  13. doi request reprint Prognostic value of 64-slice cardiac computed tomography severity of coronary artery disease, coronary atherosclerosis, and left ventricular ejection fraction
    Benjamin J W Chow
    Division of Cardiology, University of Ottawa Heart Institute, Ottawa, Ontario, Canada
    J Am Coll Cardiol 55:1017-28. 2010
    ..We sought to determine the prognostic and incremental value of coronary artery disease (CAD) severity, coronary atherosclerosis, and left ventricular ejection fraction (LVEF) measured with cardiac computed tomography angiography (CTA)...
  14. doi request reprint Effects of mitral valve surgery on myocardial energetics in patients with severe mitral regurgitation
    Benjamin J W Chow
    University of Ottawa Heart Institute, 40 Ruskin St, Ottawa, ON K1Y4W7, Canada
    Circ Cardiovasc Imaging 3:308-13. 2010
    ..We sought to determine the effects of MV surgery on forward stroke work, myocardial oxidative metabolism, and myocardial efficiency...
  15. doi request reprint Diagnostic accuracy and impact of computed tomographic coronary angiography on utilization of invasive coronary angiography
    Benjamin J W Chow
    Department of Medicine, University of Ottawa Heart Institute, Ottawa, Ontario, Canada
    Circ Cardiovasc Imaging 2:16-23. 2009
    ..Before CTA can be further accepted into clinical practice, its impact on healthcare resources needs to be better understood. We sought to determine the clinical impact of CTA on ICA referrals, CTA accuracy, and normalcy rate...
  16. pmc Prognostic value of treadmill exercise and dobutamine stress positron emission tomography
    Benjamin J W Chow
    Department of Medicine Cardiology and Nuclear Medicine, University of Ottawa Heart Institute, Ottawa, Ontario K1Y 4W7, Canada
    Can J Cardiol 25:e220-4. 2009
    ..Evidence suggests that vasodilator PET myocardial perfusion imaging (MPI) has prognostic value, but the prognostic value of treadmill exercise and dobutamine PET MPI is unknown...
  17. pmc Comparison of computed tomographic angiography versus rubidium-82 positron emission tomography for the detection of patients with anatomical coronary artery disease
    Benjamin J W Chow
    Division of Cardiology, University of Ottawa Heart Institute, Ottawa, ON, Canada
    Can J Cardiol 23:801-7. 2007
    ....
  18. ncbi request reprint Treadmill exercise produces larger perfusion defects than dipyridamole stress N-13 ammonia positron emission tomography
    Benjamin J W Chow
    Division of Cardiology, University of Ottawa Heart Institute, Ottawa, Ontario, Canada
    J Am Coll Cardiol 47:411-6. 2006
    ..The aim of this study was to compare treadmill exercise (TEX) and dipyridamole stress on the uptake and retention of N-13 ammonia...
  19. ncbi request reprint Computed tomographic coronary angiography: an alternative to invasive coronary angiography
    Benjamin J W Chow
    University of Ottawa Heart Institute, Ottawa, Ontario, Canada
    Can J Cardiol 21:933-40. 2005
    ..The practical advantages of CT angiography (in regard to safety and cost) along with its future anticipated advancements make it an attractive alternative to diagnostic coronary angiography...
  20. ncbi request reprint Prognostic significance of dipyridamole-induced ST depression in patients with normal 82Rb PET myocardial perfusion imaging
    Benjamin J W Chow
    Division of Cardiology, Department of Medicine, University of Ottawa Heart Institute, Ottawa, Ontario, Canada
    J Nucl Med 46:1095-101. 2005
    ..We sought to determine the prognostic importance of dipyridamole-induced ischemic ECG changes in patients with normal 82Rb PET myocardial perfusion images...
  21. pmc Brugada syndrome precipitated by a tricyclic antidepressant
    B J W Chow
    Heart 91:651. 2005
  22. doi request reprint Does quantification of myocardial flow reserve using rubidium-82 positron emission tomography facilitate detection of multivessel coronary artery disease?
    Maria C Ziadi
    Division of Cardiology, National Cardiac PET Centre, University of Ottawa Heart Institute, Ottawa, ON, Canada
    J Nucl Cardiol 19:670-80. 2012
    ..The aim of this study was to assess whether assessment of myocardial flow reserve (MFR) measured with (82)Rb PET is an independent predictor of severe obstructive 3-vessel CAD...
  23. doi request reprint Predictive value of cardiac computed tomography and the impact of renal function on all cause mortality (from Coronary Computed Tomography Angiography Evaluation for Clinical Outcomes)
    Girish Dwivedi
    Department of Medicine, Division of Cardiology, University of Ottawa Heart Institute, Ottawa, Ontario, Canada
    Am J Cardiol 111:1563-9. 2013
    ..Furthermore, renal dysfunction, CAD severity, and the LVEF have additive value for predicting all-cause death in patients with suspected obstructive CAD...
  24. doi request reprint Lessons from the Tc-99m shortage: implications of substituting Tl-201 for Tc-99m single-photon emission computed tomography
    Gary R Small
    Division of Cardiology, Department of Medicine, University of Ottawa Heart Institute, Ottawa, Canada
    Circ Cardiovasc Imaging 6:683-91. 2013
    ..Because Tl-201 is considered by many as a suboptimal radiotracer, we sought to understand the impact of using Tl-201 (during the Tc-99m shortage) on downstream resource utilization...
  25. ncbi request reprint What is the prognostic value of myocardial perfusion imaging using rubidium-82 positron emission tomography?
    Keiichiro Yoshinaga
    Division of Cardiology, University of Ottawa Heart Institute, Ottawa, Ontario, Canada
    J Am Coll Cardiol 48:1029-39. 2006
    ..The objective was to determine the prognostic value of rubidium-82 (82Rb) positron emission tomography (PET) myocardial perfusion imaging (MPI)...
  26. doi request reprint Prognostic assessment of coronary artery bypass patients with 64-slice computed tomography angiography: anatomical information is incremental to clinical risk prediction
    Gary R Small
    Department of Medicine Cardiology, University of Ottawa Heart Institute, Ottawa, Ontario, Canada
    J Am Coll Cardiol 58:2389-95. 2011
    ..We sought to determine the incremental prognostic value of 64 multi-slice coronary computed tomography angiography (CCTA) in coronary artery bypass graft (CABG) patients...
  27. ncbi request reprint Comparison of treadmill exercise versus dipyridamole stress with myocardial perfusion imaging using rubidium-82 positron emission tomography
    Benjamin J W Chow
    Division of Cardiology, University of Ottawa Heart Institute, Ottawa, Ontario, Canada
    J Am Coll Cardiol 45:1227-34. 2005
    ....
  28. doi request reprint Impaired myocardial flow reserve on rubidium-82 positron emission tomography imaging predicts adverse outcomes in patients assessed for myocardial ischemia
    Maria C Ziadi
    National Cardiac PET Centre, Division of Cardiology, University of Ottawa Heart Institute, Ottawa, Ontario, Canada
    J Am Coll Cardiol 58:740-8. 2011
    ..We evaluated the prognostic value of myocardial flow reserve (MFR) using rubidium-82 ((82)Rb) positron emission tomography (PET) in patients assessed for ischemia...
  29. doi request reprint The role of noninvasive imaging in coronary artery disease detection, prognosis, and clinical decision making
    Taylor Dowsley
    University of Ottawa Heart Institute, Department of Medicine Cardiology, Ottawa, Ontario, Canada
    Can J Cardiol 29:285-96. 2013
    ....
  30. doi request reprint Potential clinical and economic consequences of noncardiac incidental findings on cardiac computed tomography
    Jimmy Machaalany
    Department of Medicine Cardiology, University of Ottawa Heart Institute, 40 Ruskin Street, Ottawa, Ontario, Canada
    J Am Coll Cardiol 54:1533-41. 2009
    ..We sought to determine the incidence, clinical significance, and potential financial impact of noncardiac incidental findings (IF) identified with cardiac computed tomography (CT)...
  31. pmc Prognostic and therapeutic implications of statin and aspirin therapy in individuals with nonobstructive coronary artery disease: results from the CONFIRM (COronary CT Angiography EvaluatioN For Clinical Outcomes: An InteRnational Multicenter registry) re
    Benjamin J W Chow
    From the Department of Medicine Cardiology, University of Ottawa Heart Institute, Ottawa, Ontario, Canada B J W C, G S, Y Y, L C, R M Department of Medicine, University of Erlangen, Erlangen, Germany S A Department of Medicine, Henry Ford Hospital, Wayne State University, Detroit, MI M A M Department of Imaging, Cedars Sinai Medical Center, Los Angeles, CA D S B, V Y C, T L Department of Medicine, Harbor University of California, Los Angeles Medical Center M J B Department of Radiology, Giovanni XXIII Hospital, Monastier di Treviso, Italy F C, E M Department of Radiology, Erasmus Medical Center, Rotterdam, The Netherlands F C, E M Tennessee Heart and Vascular Institute, Hendersonville T Q C Division of Cardiology, Severance Cardiovascular Hospital, Seoul, Korea H J C William Beaumont Hospital, Royal Oaks, MI K C Baptist Cardiac and Vascular Institute, Miami, Germany
    Arterioscler Thromb Vasc Biol 35:981-9. 2015
    ..We sought to examine the risk of mortality associated with nonobstructive coronary artery disease (CAD) and to determine the impact of baseline statin and aspirin use on mortality...
  32. doi request reprint Scar imaging using multislice computed tomography versus metabolic imaging by F-18 FDG positron emission tomography: a pilot study
    Girish Dwivedi
    University of Ottawa Heart Institute, Department of Medicine Cardiology, Canada
    Int J Cardiol 168:739-45. 2013
    ..A pilot study was undertaken to determine quantitative and qualitative agreement between metabolic viability imaging and scar imaging using FDG PET and multislice CT respectively...
  33. doi request reprint Epicardial adipose tissue thickness as a predictor of impaired microvascular function in patients with non-obstructive coronary artery disease
    Mohammed S Alam
    Department of Medicine Cardiology, University of Ottawa Heart Institute, 40 Ruskin Street, Ottawa, ON, K1Y 4W7, Canada
    J Nucl Cardiol 20:804-12. 2013
    ..To determine if increased epicardial adipose tissue (EAT) measured by cardiac CT could be associated with impaired myocardial flow reserve (MFR) in patients with non-obstructive coronary artery disease (CAD)...
  34. ncbi request reprint Does electrocardiographic Q wave burden predict the extent of scarring or hibernating myocardium as quantified by positron emission tomography?
    Karthikeyan Ananthasubramaniam
    National Cardiac PET Centre, Department of Medicine, University of Ottawa Heart Institute, Ontario
    Can J Cardiol 21:51-6. 2005
    ..The extent of Q wave 'burden' on electrocardiograms (ECGs) has not been correlated with the extent of scarring and hibernation as determined quantitatively by positron emission tomography (PET)...
  35. doi request reprint Right and left ventricular uptake with Rb-82 PET myocardial perfusion imaging: markers of left main or 3 vessel disease
    Arun Abraham
    Department of Medicine Cardiology, University of Ottawa Heart Institute, 40 Ruskin Street, Ottawa, ON, K1Y 4W7, Canada
    J Nucl Cardiol 17:52-60. 2010
    ..Can quantification of peak left (LV) and right (RV) ventricular Rb-82 uptake measurements identify patients with left main or 3 vessel disease?..
  36. ncbi request reprint Is septal glucose metabolism altered in patients with left bundle branch block and ischemic cardiomyopathy?
    Kerry Thompson
    Division of Cardiology, National Cardiac PET Centre, University of Ottawa Heart Institute, Ottawa, Ontario, Canada
    J Nucl Med 47:1763-8. 2006
    ..The aim of this study was to determine the effect of LBBB on septal metabolism in patients with ICM, LV dysfunction, and LBBB...
  37. doi request reprint A clinical model to identify patients with high-risk coronary artery disease
    Yelin Yang
    Department of Medicine Cardiology, University of Ottawa Heart Institute, Ottawa, Canada
    JACC Cardiovasc Imaging 8:427-34. 2015
    ..This study sought to develop a clinical model that identifies patients with and without high-risk coronary artery disease (CAD)...
  38. doi request reprint Prognostic value of Rb-82 positron emission tomography myocardial perfusion imaging in coronary artery bypass patients
    Ally Pen
    Department of Medicine Cardiology and Nuclear Medicine, The University of Ottawa Heart Institute, 40 Ruskin Street, Ottawa, ON, Canada K1Y 4W7
    Eur Heart J Cardiovasc Imaging 15:787-92. 2014
    ..PET MPI has recently been shown to provide incremental risk stratification for patients with suspected coronary artery disease (CAD), but the prognostic utility of PET MPI in CABG patients has not been well studied...
  39. doi request reprint Incremental diagnostic benefit of resolution recovery software in patients with equivocal myocardial perfusion single-photon emission computed tomography (SPECT)
    Mohammed A Qutub
    Department of Medicine Cardiology, University of Ottawa Heart Institute, Ottawa, ON, Canada
    J Nucl Cardiol 20:545-52. 2013
    ..Its utility with "full-time, full-dose" acquisition has not been well studied...
  40. doi request reprint Characterization of mitral valve prolapse with cardiac computed tomography: comparison to echocardiographic and intraoperative findings
    Nina Ghosh
    Division of Cardiology, University of Ottawa Heart Institute, 40 Ruskin Street, Ottawa, ON, K1Y 4W7, Canada
    Int J Cardiovasc Imaging 28:855-63. 2012
    ..Cardiac CT was able to identify patients with MVP but had difficulty identifying the prolapsed scallops compared to echocardiography. Single-source CT may not be ready for characterization of individual mitral valve scallops...
  41. doi request reprint Rates of downstream invasive coronary angiography and revascularization: computed tomographic coronary angiography vs. Tc-99m single photon emission computed tomography
    Vikas Tandon
    Division of Cardiology, University of Ottawa Heart Institute, 40 Ruskin Street, Ottawa, ON, Canada K1Y 4W7
    Eur Heart J 33:776-82. 2012
    ..We followed a cohort of 64-slice CTA patients and a matched cohort of Tc-99m SPECT patients to determine downstream referrals for ICA and revascularization...
  42. doi request reprint Usefulness of the Agatston score = 0 to exclude ischemic cardiomyopathy in patients with heart failure
    Joseph G Abunassar
    Department of Medicine, University of Ottawa Heart Institute, Ontario, Canada
    Am J Cardiol 107:428-32. 2011
    ..In conclusion, an Agatston score equal to 0 confers a very low likelihood of obstructive CAD, appears to rule out high-risk CAD, and thus may be used to rule out ischemic cardiomyopathy in patients with HF...
  43. doi request reprint Anatomic versus physiologic assessment of coronary artery disease. Role of coronary flow reserve, fractional flow reserve, and positron emission tomography imaging in revascularization decision-making
    K Lance Gould
    Weatherhead PET Center for Preventing and Reversing Atherosclerosis, Division of Cardiology, Department of Medicine, University of Texas Medical School at Houston, Houston, Texas Electronic address
    J Am Coll Cardiol 62:1639-53. 2013
    ..We clarify the basic concepts that hold true for whatever technology measures coronary physiology directly and reliably, here focusing on positron emission tomography and its interplay with intracoronary measurements. ..
  44. doi request reprint Measuring coronary artery calcification using positron emission tomography-computed tomography attenuation correction images
    Ilias Mylonas
    Department of Medicine Cardiology, University of Ottawa Heart Institute, 40 Ruskin Street, Ottawa, ON, Canada K1Y 4W7
    Eur Heart J Cardiovasc Imaging 13:786-92. 2012
    ..We sought to understand the relationship between CAC measured using cardiac computed tomography (CT) and CAC using ACCT images obtained during cardiac PET perfusion imaging...
  45. ncbi request reprint Application of cardiac molecular imaging using positron emission tomography in evaluation of drug and therapeutics for cardiovascular disorders
    Keiichiro Yoshinaga
    National Cardiac PET Centre, University of Ottawa Heart Institute, Ontario, Canada
    Curr Pharm Des 11:903-32. 2005
    ..This paper will also review the application of receptor ligand imaging and the principles of using surrogate physiological end-points in early drug development and evaluation...
  46. ncbi request reprint The Prognostic Value of Percentage Total Plaque Score Adjusted to Age: A Potential Marker of Coronary Vascular Age
    Chadi Ayoub
    Department of Medicine Cardiology, University of Ottawa Heart Institute, Canada University of Sydney, New South Wales, Australia
    Angiology . 2016
    ..We propose a novel measure, percentage TPS adjusted to age (%TPS/age), that may reflect vascular age and potentially more rapidly progressive atherosclerosis and evaluate its potential prognostic value...
  47. doi request reprint Quantifying coronary artery calcification from a contrast-enhanced cardiac computed tomography angiography study
    Ilias Mylonas
    Department of Medicine Cardiology, University of Ottawa Heart Institute, 40 Ruskin Street, Ottawa, ON, Canada K1Y 4W7
    Eur Heart J Cardiovasc Imaging 15:210-5. 2014
    ..Thus each scan individually contributes to the total radiation dose...
  48. ncbi request reprint Lesion characteristics and coronary stent selection with computed tomographic coronary angiography: a pilot investigation comparing CTA, QCA and IVUS
    Malek Kass
    Department of Medicine Cardiology, University of Ottawa Heart Institute, 40 Ruskin Street, Ottawa, Ontario, Canada K1Y 4W7
    J Invasive Cardiol 22:328-34. 2010
    ..Computed tomographic coronary angiography (CTA) has been shown to correlate well with QCA and IVUS in the assessment of coronary stenoses and may also have a role in stent guidance...
  49. doi request reprint Ontario multidetector computed tomographic coronary angiography study: field evaluation of diagnostic accuracy
    Benjamin J W Chow
    Department of Radiology, University of Ottawa Heart Institute, Ontario, Canada
    Arch Intern Med 171:1021-9. 2011
    ..The true diagnostic accuracy of CTCA in the "real world" remains uncertain. We conducted a field evaluation comparing multidetector CTCA with invasive CA (ICA) to understand CTCA's diagnostic accuracy in a real-world setting...
  50. doi request reprint Comparison of (18)F-fluorodeoxyglucose positron emission tomography (FDG PET) and cardiac magnetic resonance (CMR) in corticosteroid-naive patients with conduction system disease due to cardiac sarcoidosis
    Hiroshi Ohira
    Molecular Function and Imaging Program, National Cardiac PET Centre, University of Ottawa Heart Institute, 40 Ruskin Street, Ottawa, ON, Canada, K1Y 4W7
    Eur J Nucl Med Mol Imaging 43:259-69. 2016
    ..The relative diagnostic value of these has not been well studied. The aim was to compare these imaging modalities in this population...
  51. ncbi request reprint Prognostic significance of blood pressure response during vasodilator stress Rb-82 positron emission tomography myocardial perfusion imaging
    Bradley Witbrodt
    Division of Cardiology, Department of Medicine, Emory University School of Medicine, 1462 Clifton Rd, Room 503, Atlanta, GA, 30322, USA
    J Nucl Cardiol . 2016
    ....
  52. doi request reprint Assessment of left ventricular ejection fraction using low radiation dose computed tomography
    Yiqi Yang
    Division of Cardiology, University of Ottawa Heart Institute, 40 Ruskin Street, Ottawa, ON, K1Y 4W7, Canada
    J Nucl Cardiol 23:414-21. 2016
    ..However, given its limited temporal resolution and radiation, there has been initial resistance to use CT to measure LVEF. Developing an accurate, fast, low radiation dose protocol is desirable...
  53. doi request reprint Obesity and coronary artery calcification: Can it explain the obesity-paradox?
    Ahmed Aljizeeri
    Department of Medicine, University of Ottawa, Ottawa, Canada
    Int J Cardiovasc Imaging 31:1063-70. 2015
    ..BF% was associated with the extent of CAC and higher BF% was associated with higher category of CAC severity in men only. These results suggest that further study is needed to better understand the obesity-paradox...
  54. doi request reprint Prognostic value of rubidium-82 positron emission tomography in patients after heart transplant
    Brian A Mc Ardle
    From the Division of Cardiology, Department of Medicine B A M A, R A D, G R S, T D R, G D, Y Y, H H, L M M, E S, R H, R S B, B J W C, National Cardiac PET Center B A M A, R A D, T D R, R H, A G, R S B, R A D, B J W C, and Division of Cardiology, Department of Medicine, Cardiovascular Research Methods Center L C, University of Ottawa Heart Institute Ottawa, Canada
    Circ Cardiovasc Imaging 7:930-7. 2014
    ..Positron emission tomography using rubidium-82 allows quantification of absolute myocardial blood flow and may have utility for risk stratification in this population...
  55. doi request reprint Validation of two-dimensional methods for left atrial volume measurement: a comparison of echocardiography with cardiac computed tomography
    Maha A Al-Mohaissen
    Department of Medicine Cardiology, University of Ottawa Heart Institute, Ottawa, Canada
    Echocardiography 30:1135-42. 2013
    ..The objective of the study was to evaluate the accuracy of methods to calculate LAVol by 2DTTE or cardiac computed tomography (CT)...
  56. doi request reprint Integrating anatomical and functional imaging for the assessment of coronary artery disease
    Andrea K Y Lee
    Department of Medicine Cardiology, University of British Columbia, Canada
    Expert Rev Cardiovasc Ther 11:1301-10. 2013
    ..We will provide an overview of the evidence to date on the anatomical and functional stratification of CAD and current hybrid techniques. ..
  57. doi request reprint Discordance between Framingham Risk Score and atherosclerotic plaque burden
    Ally Pen
    Department of Medicine Cardiology, The University of Ottawa Heart Institute, Ottawa, ON, Canada
    Eur Heart J 34:1075-82. 2013
    ..The objective of this study is to investigate the association of Framingham Risk Score (FRS) with computed tomography angiography (CTA) measures of coronary atherosclerosis...
  58. doi request reprint Advances in cardiac SPECT and PET imaging: overcoming the challenges to reduce radiation exposure and improve accuracy
    Gary R Small
    Division of Cardiology, Department of Medicine, University of Ottawa and the University of Ottawa Heart Institute, Ottawa, Ontario, Canada
    Can J Cardiol 29:275-84. 2013
    ..Instead, even with the pressure to reduce radiation exposure, the future continues to look bright for cardiac SPECT and PET...
  59. doi request reprint Low-dose cardiac imaging: reducing exposure but not accuracy
    Gary R Small
    Division of Cardiology, University of Ottawa Heart Institute, Ottawa, Ontario K1Y 4W7, Canada
    Expert Rev Cardiovasc Ther 10:89-104. 2012
    ..Improvements in imaging camera technology, image acquisition protocols and image processing have lead to reductions in patient radiation exposure without compromising imaging diagnostic accuracy...
  60. doi request reprint Determining patient prognosis using computed tomography coronary angiography
    Mustapha H Kazmi
    University of Ottawa Heart Institute, Division of Cardiology, 40 Ruskin Street, Ottawa, ON, K1Y 4W7, Canada
    Expert Rev Med Devices 8:647-57. 2011
    ....
  61. ncbi request reprint The role of nuclear cardiac imaging in risk stratification of sudden cardiac death
    Daniel Juneau
    National Cardiac PET Centre, Division of Cardiology, Department of Medicine, University of Ottawa Heart Institute, 40 Ruskin Street, Ottawa, ON, K1Y 4W7, Canada
    J Nucl Cardiol 23:1380-1398. 2016
    ..We will discuss how these can be used to better understand SCD and better stratify patient with both ischemic and non-ischemic cardiomyopathy...
  62. doi request reprint Single low-dose CT scan optimized for rest-stress PET attenuation correction and quantification of coronary artery calcium
    Tyler S Kaster
    The National Cardiac PET Centre, Division of Cardiology, University of Ottawa Heart Institute, 40 Ruskin Street, Ottawa, ON, K1Y 4W7, Canada
    J Nucl Cardiol 22:419-28. 2015
    ..This study aimed to determine if a low-dose CTAC scan can also accurately quantify coronary artery calcium...
  63. doi request reprint Serum heat shock protein 27 levels represent a potential therapeutic target for atherosclerosis: observations from a human cohort and treatment of female mice
    Tara A Seibert
    University of Ottawa Heart Institute, Ottawa, Ontario, Canada
    J Am Coll Cardiol 62:1446-54. 2013
    ..The aim of this study was to evaluate the potential of serum heat shock protein 27 (HSP27) as a therapeutic target in coronary artery disease...
  64. doi request reprint Can left ventricular end-diastolic volumes be estimated with prospective ECG-gated CT coronary angiography?
    Prateek J Khatri
    Toronto General Hospital, Department of Medicine, 200 Elizabeth Street, Eaton Building 14 217, Toronto, ON, Canada M5G 2C4
    Eur J Radiol 81:226-9. 2012
    ..Given that LV volumes have prognostic value, the ability to estimate LV end diastolic volume (EDV) may be clinically desirable...
  65. pmc CCS/CAR/CANM/CNCS/CanSCMR joint position statement on advanced noninvasive cardiac imaging using positron emission tomography, magnetic resonance imaging and multidetector computed tomographic angiography in the diagnosis and evaluation of ischemic heart
    R S B Beanlands
    University of Ottawa Heart Institute, Ottawa, Canada
    Can J Cardiol 23:107-19. 2007
    ..The aim of the present position statement was to systematically review existing literature to define Canadian recommendations for their clinical use...
  66. doi request reprint Coronary Artery Disease in French Canadians-Investigation of a Suggested Vulnerable Population
    Chadi Ayoub
    Department of Medicine Cardiology, University of Ottawa Heart Institute, Ottawa, Ontario, Canada University of Sydney, New South Wales, Australia
    Can J Cardiol 32:1240-1245. 2016
    ..We sought to compare the prevalence of CAD using coronary computed tomographic angiography (CCTA) in French Canadians and non-French white Canadians...
  67. doi request reprint Canceled coronary computed tomography angiography: Downstream testing and outcomes
    Manuja Premaratne
    Department of Medicine Cardiology, University of Ottawa Heart Institute, Ottawa, Canada Department of Medicine Cardiology, Frankston Hospital, Frankston, Australia
    Int J Cardiol 227:457-461. 2017
    ..Downstream resource utilization and its impact on outcomes after a canceled CCTA have not been well studied. We sought to understand downstream resource utilization and patient outcomes after canceled CCTA...
  68. doi request reprint A single slice measure of epicardial adipose tissue can serve as an indirect measure of total epicardial adipose tissue burden and is associated with obstructive coronary artery disease
    Thomas Tran
    Department of Medicine Cardiology, University of Ottawa Heart Institute, The Ottawa Hospital, 40 Ruskin Street, Ottawa, ON, Canada K1Y 4W7
    Eur Heart J Cardiovasc Imaging 15:423-30. 2014
    ..To evaluate the practical use of the single slice measurement of epicardial adipose tissue (EAT) at the level of the left main coronary artery (EATLM) in predicting the presence of obstructive coronary artery disease (CAD)...
  69. doi request reprint CT vs SPECT: CT is the first-line test for the diagnosis and prognosis of stable coronary artery disease
    Ahmed Aljizeeri
    Department of Medicine Cardiology, University of Ottawa Heart Institute, 40 Ruskin Street, Ottawa, ON, K1Y 4W7, Canada
    J Nucl Cardiol 20:465-72. 2013
    ..Therefore, the question that begs to be addressed is whether CCTA can be utilized as a first line test in establishing the diagnosis and prognosis of CAD...
  70. doi request reprint Established and emerging dose reduction methods in cardiac computed tomography
    Gary R Small
    Division of Cardiology, University of Ottawa Heart Institute, 40 Ruskin Street, Ottawa, ON, K1Y4W7, Canada
    J Nucl Cardiol 18:570-9. 2011
    ....
  71. ncbi request reprint What are the most useful and trustworthy noninvasive anatomic markers of existing vascular disease?
    Benjamin J W Chow
    Department of Laboratory Medicine, Room 123, Ottawa Hospital, Civic Campus, 1053 Carling Avenue, Ottawa, Ontario K1Y 4E9, Canada
    Curr Cardiol Rep 8:439-45. 2006
    ..We review the pathology of the vulnerable atherosclerotic plaque and recent innovations in imaging modalities to assess plaque complication risk...
  72. doi request reprint Coronary computed tomography angiography predicts subsequent cardiac outcome events: results of the Visipaque CCTA registry study
    Matthew J Budoff
    aDavid Geffen School of Medicine, Harbor UCLA Medical Center, Division of Cardiology, Los Angeles Biomedical Research Institute, Los Angeles, California bOverland Park, Kansas cDepartment of Medicine, University Health Care System, Augusta, Georgia dMobile, Alabama, USA eDepartment of Medicine, University of Ottawa Heart Institute, Ottawa, Ontario, Canada
    Coron Artery Dis 26:301-7. 2015
    ..To evaluate the diagnostic performance and predictive value of coronary computed tomography angiography (CCTA) on subsequent cardiac outcomes...
  73. pmc Limitations of free-form-text diagnostic requisitions as a tool for evaluating adherence to appropriate use criteria for transthoracic echocardiography
    Behnam Banihashemi
    Department of Medicine, Division of Cardiology, University of Ottawa Heart Institute, University of Ottawa, 40 Ruskin Street, Rm 3407B, K1Y 4W7 Ottawa, Ontario, Canada
    Cardiovasc Ultrasound 13:4. 2015
    ..We investigated whether standard free-form-text TTE referral requisitions can be used to evaluate AUC adherence...
  74. doi request reprint Impact of SPECT myocardial perfusion imaging on cardiac care
    Peter Lugomirski
    Division of Cardiology, University of Ottawa Heart Institute, 40 Ruskin Street, Ottawa, ON K1Y 4W7, Canada
    Expert Rev Cardiovasc Ther 12:1247-9. 2014
    ..It acts as guide for therapy and has the ability to assess effectiveness of therapy. The use of SPECT myocardial perfusion imaging has also been shown to be cost-effective compared to other modalities in cardiology. ..
  75. ncbi request reprint Cardiovascular magnetic resonance for diagnosis of coronary artery disease: quo vadis?
    Girish Dwivedi
    Department of Medicine Cardiology, Heart Institute, University of Ottawa, Ottawa, ON, Canada
    Expert Rev Med Devices 9:219-24. 2012
    ..In summary, the results of this study confirm the promise for CMR, but further work and larger multicenter studies are required before its adoption into routine clinical practice...
  76. ncbi request reprint Assessment of cardiac computed tomography-myocardial perfusion imaging - promise and challenges -
    Girish Dwivedi
    Department of Medicine Cardiology, University of Ottawa Heart Institute, Ottawa, Canada
    Circ J 76:544-52. 2012
    ..This review will provide an overview of this novel perfusion imaging method, its underlying principles, evolution, limitations and future directions...
  77. doi request reprint Interventional valve surgery: building a team and working together
    Marc Ruel
    Division of Cardiac Surgery, University of Ottawa Heart Institute, Ottawa, Ontario, Canada
    Semin Thorac Cardiovasc Surg 22:145-9. 2010
    ....
  78. doi request reprint Metastatic breast cancer: the role of pegylated liposomal doxorubicin after conventional anthracyclines
    Shailendra Verma
    Ottawa Hospital Cancer Centre, 501 Smyth Road, Box 914, Ottawa, Ontario, Canada K1H 8L6
    Cancer Treat Rev 34:391-406. 2008
    ....
  79. ncbi request reprint Impending paradoxical embolus: a case report and review of the literature
    Benjamin J W Chow
    Department of Medicine, University of Ottawa Heart Institute, University of Ottawa, Ottawa, Ontario, Canada
    Can J Cardiol 19:1426-32. 2003
    ..Based on the literature to date, we recommend that patients with impending paradoxical embolism be treated with initial systemic heparinization followed by emergent surgical embolectomy if the surgical risks are acceptable...
  80. ncbi request reprint Prevalence and significance of lead-related thrombi in patients with implantable cardioverter defibrillators
    Benjamin J W Chow
    Division of Cardiology, University of Ottawa Heart Institute, Ottawa, Ontario, Canada
    Am J Cardiol 91:88-90. 2003