Kwan Leung Chan

Summary

Affiliation: University of Ottawa Heart Institute
Country: Canada

Publications

  1. pmc Routine versus selective cardiac magnetic resonance in non-ischemic heart failure - OUTSMART-HF: study protocol for a randomized controlled trial (IMAGE-HF (heart failure) project 1-B)
    Ian Paterson
    Mazankowski Alberta Heart Institute, University of Alberta, Edmonton, AB, Canada
    Trials 14:332. 2013
  2. pmc Evaluating the effectiveness of rosuvastatin in preventing the progression of diastolic dysfunction in aortic stenosis: A substudy of the aortic stenosis progression observation measuring effects of rosuvastatin (ASTRONOMER) study
    Davinder S Jassal
    Cardiology Division, Department of Internal Medicine, St Boniface General Hospital, Winnipeg, Manitoba, Canada
    Cardiovasc Ultrasound 9:5. 2011
  3. ncbi request reprint Rationale, design, and baseline characteristics of a randomized trial to assess the effect of cholesterol lowering on the progression of aortic stenosis: the Aortic Stenosis Progression Observation: Measuring Effects of Rosuvastatin (ASTRONOMER) trial
    Kwan Leung Chan
    Division of Cardiology, University of Ottawa Heart Institute, Ottawa, Ontario, Canada
    Am Heart J 153:925-31. 2007
  4. ncbi request reprint Effect of long-term aspirin use on embolic events in infective endocarditis
    Kwan Leung Chan
    University of Ottawa Heart Institute, Ottawa, Ontario, Canada
    Clin Infect Dis 46:37-41. 2008
  5. ncbi request reprint Effect of Lipid lowering with rosuvastatin on progression of aortic stenosis: results of the aortic stenosis progression observation: measuring effects of rosuvastatin (ASTRONOMER) trial
    Kwan Leung Chan
    University of Ottawa Heart Institute, Ottawa, Ontario, Canada
    Circulation 121:306-14. 2010
  6. ncbi request reprint Comparison of real-time 3-dimensional echocardiography with conventional 2-dimensional echocardiography in the assessment of structural heart disease
    Kwan Leung Chan
    University of Ottawa Heart Institute, Ontario, Canada
    J Am Soc Echocardiogr 17:976-80. 2004
  7. ncbi request reprint Effect of rosuvastatin on C-reactive protein and progression of aortic stenosis
    Kwan Leung Chan
    Division of Cardiology, University of Ottawa Heart Institute, 40 Ruskin Street, Room H3412, Ottawa, ON K1Y 4W7 Canada
    Am Heart J 161:1133-9. 2011
  8. ncbi request reprint A randomized trial of aspirin on the risk of embolic events in patients with infective endocarditis
    Kwan Leung Chan
    Department of Medicine, University of Ottawa and University of Ottawa Heart Institute, 40 Ruskin Street, Ottawa, Ontario, Canada K1Y 4W7
    J Am Coll Cardiol 42:775-80. 2003
  9. ncbi request reprint Is aortic stenosis a preventable disease?
    Kwan Leung Chan
    Division of Cardiology, University of Ottawa Heart Institute, Ottawa, Ontario, Canada
    J Am Coll Cardiol 42:593-9. 2003
  10. ncbi request reprint Functional and echocardiographic improvement following multisite biventricular pacing for congestive heart failure
    Kwan Leung Chan
    University of Ottawa Heart Institute, Ontario, Canada
    Can J Cardiol 19:387-90. 2003

Collaborators

Detail Information

Publications35

  1. pmc Routine versus selective cardiac magnetic resonance in non-ischemic heart failure - OUTSMART-HF: study protocol for a randomized controlled trial (IMAGE-HF (heart failure) project 1-B)
    Ian Paterson
    Mazankowski Alberta Heart Institute, University of Alberta, Edmonton, AB, Canada
    Trials 14:332. 2013
    ..This will lead to a reduction in the non-specific diagnoses of idiopathic dilated cardiomyopathy and HF with preserved ejection fraction...
  2. pmc Evaluating the effectiveness of rosuvastatin in preventing the progression of diastolic dysfunction in aortic stenosis: A substudy of the aortic stenosis progression observation measuring effects of rosuvastatin (ASTRONOMER) study
    Davinder S Jassal
    Cardiology Division, Department of Internal Medicine, St Boniface General Hospital, Winnipeg, Manitoba, Canada
    Cardiovasc Ultrasound 9:5. 2011
    ..Little is known however, on the utility of TDI in the serial assessment of diastolic abnormalities in AS...
  3. ncbi request reprint Rationale, design, and baseline characteristics of a randomized trial to assess the effect of cholesterol lowering on the progression of aortic stenosis: the Aortic Stenosis Progression Observation: Measuring Effects of Rosuvastatin (ASTRONOMER) trial
    Kwan Leung Chan
    Division of Cardiology, University of Ottawa Heart Institute, Ottawa, Ontario, Canada
    Am Heart J 153:925-31. 2007
    ..The secondary objectives are to determine the effect of rosuvastatin on the rate of cardiac death and aortic valve replacement and to assess the time to outcome during a follow-up of 3 to 5 years...
  4. ncbi request reprint Effect of long-term aspirin use on embolic events in infective endocarditis
    Kwan Leung Chan
    University of Ottawa Heart Institute, Ottawa, Ontario, Canada
    Clin Infect Dis 46:37-41. 2008
    ..The purpose of the study is to assess the effect of long-term daily aspirin use on the risk of embolic events in patients with infective endocarditis...
  5. ncbi request reprint Effect of Lipid lowering with rosuvastatin on progression of aortic stenosis: results of the aortic stenosis progression observation: measuring effects of rosuvastatin (ASTRONOMER) trial
    Kwan Leung Chan
    University of Ottawa Heart Institute, Ottawa, Ontario, Canada
    Circulation 121:306-14. 2010
    ..Aortic stenosis (AS) is an active process with similarities to atherosclerosis. The objective of this study was to assess the effect of cholesterol lowering with rosuvastatin on the progression of AS...
  6. ncbi request reprint Comparison of real-time 3-dimensional echocardiography with conventional 2-dimensional echocardiography in the assessment of structural heart disease
    Kwan Leung Chan
    University of Ottawa Heart Institute, Ontario, Canada
    J Am Soc Echocardiogr 17:976-80. 2004
    ..It can provide new and useful anatomic insight, particularly in patients with mitral valve disease and congenital heart disease. Suboptimal image quality remains a problem for real-time 3D echocardiography in some patients...
  7. ncbi request reprint Effect of rosuvastatin on C-reactive protein and progression of aortic stenosis
    Kwan Leung Chan
    Division of Cardiology, University of Ottawa Heart Institute, 40 Ruskin Street, Room H3412, Ottawa, ON K1Y 4W7 Canada
    Am Heart J 161:1133-9. 2011
    ..The purpose of the study was to examine the role of high-sensitivity CRP and its interaction with rosuvastatin on the progression of AS...
  8. ncbi request reprint A randomized trial of aspirin on the risk of embolic events in patients with infective endocarditis
    Kwan Leung Chan
    Department of Medicine, University of Ottawa and University of Ottawa Heart Institute, 40 Ruskin Street, Ottawa, Ontario, Canada K1Y 4W7
    J Am Coll Cardiol 42:775-80. 2003
    ..This study examined the effect of aspirin on the risk of embolic events in infective endocarditis (IE)...
  9. ncbi request reprint Is aortic stenosis a preventable disease?
    Kwan Leung Chan
    Division of Cardiology, University of Ottawa Heart Institute, Ottawa, Ontario, Canada
    J Am Coll Cardiol 42:593-9. 2003
    ..The time has come to initiate prospective studies to assess the effect of cholesterol lowering on the progression of AS...
  10. ncbi request reprint Functional and echocardiographic improvement following multisite biventricular pacing for congestive heart failure
    Kwan Leung Chan
    University of Ottawa Heart Institute, Ontario, Canada
    Can J Cardiol 19:387-90. 2003
    ..Heart failure remains a major cause of morbidity and mortality despite advances in pharmacological treatment. Recently, multisite biventricular pacing has been used in the treatment of patients with heart failure...
  11. ncbi request reprint Echocardiography in right-sided endocarditis
    Kwan Chan
    Ottawa Heart Institute, Ont
    Clin Invest Med 25:134-6. 2002
  12. pmc Early clinical course and long-term outcome of patients with infective endocarditis complicated by perivalvular abscess
    Kwan Leung Chan
    University of Ottawa Heart Institute, Ont
    CMAJ 167:19-24. 2002
    ..Perivalvular abscess is an ominous development in patients with infective endocarditis. There is little information concerning the long-term outcome of these patients...
  13. ncbi request reprint Diagnosis of left atrial sarcoma by transvenous endocardial biopsy
    K L Chan
    University of Ottawa Heart Institute, 4o Ruskin St, Ottawa, Ontario K1Y 4W7, Canada
    Can J Cardiol 17:206-8. 2001
    ..A case of left atrial sarcoma in which the diagnosis was made by transvenous biopsy using the trans-septal approach is reported. The procedure was monitored by transesophageal echocardiography...
  14. ncbi request reprint A continuous murmur after surgery for dissecting ascending aortic aneurysm
    K L Chan
    University of Ottawa Heart Institute, Ontario, Canada
    Ann Thorac Surg 69:1929-31. 2000
    ..A careful physical examination and the selective use of imaging tests can differentiate this relatively benign complication from the more serious causes of a continuous murmur in this setting...
  15. ncbi request reprint Acute aortic intimal tear without a mobile flap mimicking an intramural hematoma
    Luc M Beauchesne
    Division of Cardiology, University of Ottawa Heart Institute, Ontario, Canada
    J Am Soc Echocardiogr 16:285-8. 2003
    ..We present a case of an acute aortic syndrome with unusual features on transesophageal echocardiography...
  16. ncbi request reprint Validation of two-dimensional methods for left atrial volume measurement: a comparison of echocardiography with cardiac computed tomography
    Maha A Al-Mohaissen
    Department of Medicine Cardiology, University of Ottawa Heart Institute, Ottawa, Canada
    Echocardiography 30:1135-42. 2013
    ..The objective of the study was to evaluate the accuracy of methods to calculate LAVol by 2DTTE or cardiac computed tomography (CT)...
  17. ncbi request reprint Aortic valve area discrepancy by Gorlin equation and Doppler echocardiography continuity equation: relationship to flow in patients with valvular aortic stenosis
    I G Burwash
    Department of Medicine, Victoria General Hospital, Dalhousie University, Halifax, Canada
    Can J Cardiol 16:985-92. 2000
    ....
  18. ncbi request reprint Angiotensin receptor blockade and exercise capacity in adults with systemic right ventricles: a multicenter, randomized, placebo-controlled clinical trial
    Annie Dore
    Department of Medicine, Montreal Heart Institute, Montreal, Canada
    Circulation 112:2411-6. 2005
    ..Pharmacological blockade of the renin-angiotensin system improves exercise tolerance in patients with left ventricular dysfunction, yet its impact on patients with systemic right ventricles (RVs) remains unknown...
  19. ncbi request reprint Pathology of isolated atrial infarction: case report and review of the literature
    Kristopher S Cunningham
    Department of Pathology, University Health Network, University of Toronto, Toronto, Ontario, Canada
    Cardiovasc Pathol 17:183-5. 2008
    ..The presentation and causes of isolated atrial infarction are discussed...
  20. ncbi request reprint Contemporary midterm echocardiographic outcomes of Bentall procedure and aortic valve sparing root replacement
    Hadi Toeg
    Division of Cardiac Surgery, University of Ottawa Heart Institute, Ottawa, Ontario, Canada
    Ann Thorac Surg 98:590-6. 2014
    ..While aortic valve preservation reduces the risk of valve-related complications, little is known about echocardiographic differences at follow-up between these 2 strategies...
  21. ncbi request reprint Functional significance of elevated mitral gradients after repair for degenerative mitral regurgitation
    Kwan Leung Chan
    University of Ottawa Heart Institute, Ottawa, Ontario, Canada
    Circ Cardiovasc Imaging 6:1041-7. 2013
    ..We have observed that elevated mitral gradients can develop in some patients after mitral valve repair for degenerative mitral regurgitation...
  22. ncbi request reprint Tricuspid regurgitation following implantation of a pacemaker/cardioverter-defibrillator
    Maha A Al-Mohaissen
    Division of Cardiology, University of Ottawa Heart Institute, 40 Ruskin Street, Room H3412, Ottawa, ON, K1Y 4W7, Canada
    Curr Cardiol Rep 15:357. 2013
    ..Third, this is an iatrogenic complication and therefore potentially preventable. This review discusses the prevalence, mechanisms, and risk factors of LITR as well as the management and potential strategies to prevent its occurrence...
  23. pmc Impact of blood pressure on the Doppler echocardiographic assessment of severity of aortic stenosis
    Stephen H Little
    Division of Cardiology, Department of Medicine, University of Ottawa Heart Institute, Ottawa, Ontario, Canada
    Heart 93:848-55. 2007
    ..To investigate the impact of blood pressure (BP) on the Doppler echocardiographic (Doppler-echo) evaluation of severity of aortic stenosis (AS)...
  24. pmc Native anomalous left coronary artery from the pulmonary artery in an adult: Evidence of impaired coronary flow reserve by rubidium-82 positron emission tomography quantification
    Saad Mahmoud
    Division of Cardiology, University of Ottawa Heart Institute, Ottawa, Canada
    Can J Cardiol 22:1069-70. 2006
  25. ncbi request reprint Prevalence and mechanism of tricuspid regurgitation following implantation of endocardial leads for pacemaker or cardioverter-defibrillator
    Maha A Al-Mohaissen
    Division of Cardiology University of Ottawa Heart Institute, Ottawa, Ontario, Canada
    J Am Soc Echocardiogr 25:245-52. 2012
    ..A better understanding of the mechanism of lead-induced tricuspid regurgitation will be essential to the development of preventive strategies, which can then be tested in future clinical trials...
  26. ncbi request reprint Impact of three-dimensional echocardiography in valvular heart disease
    Omid Salehian
    Echocardiography Laboratory, Division of Cardiology, University of Ottawa Heart Institute, Ottawa, Ontario, Canada
    Curr Opin Cardiol 20:122-6. 2005
    ..These advances have also provided valuable insights into cardiac function. The purpose of this review is to describe the recent developments in 3D echocardiography in assessing valvular heart disease...
  27. ncbi request reprint Thermal therapy: a viable adjunct in the treatment of heart failure?
    Tofy Mussivand
    University of Ottawa Heart Institute, Ottawa, Ontario, Canada
    Congest Heart Fail 14:180-6. 2008
    ..The clinical evidence highlights repeatable and compelling data showing that thermal therapy may provide an important and viable adjunct in the treatment of heart failure...
  28. ncbi request reprint Residual sinus venosus atrial septal defect after surgical closure of atrial septal defect
    S Fagan
    University of Ottawa Heart Institute, Ontario, Canada
    J Am Soc Echocardiogr 14:738-41. 2001
    ..The residual defects were the sinus venosus type near the orifice of the inferior vena cava. Preoperative and intraoperative transesophageal echocardiography may aid in the detection and facilitate the successful repair of these defects...
  29. ncbi request reprint Prosthetic valve fungal endocarditis due to histoplasmosis
    P A Isotalo
    Department of Pathology and Laboratory Medicine, University of Ottawa, Ottawa, Canada
    Can J Cardiol 17:297-303. 2001
    ..The patient was treated with amphotericin and has been doing well in the two years since his surgery. The diagnosis and management of fungal endocarditis are emphasized...
  30. ncbi request reprint Reliability of transthoracic echocardiography in the assessment of aortic valve morphology: pathological correlation in 178 patients
    K L Chan
    Department of Medicine, University of Ottawa Heart Institute, Ontario
    Can J Cardiol 15:48-52. 1999
    ..To examine patient characteristics affecting the utility of transthoracic echocardiography in determining aortic valve morphology, particularly for the diagnosis of congenital bicuspid aortic valve (BAV)...
  31. ncbi request reprint Device closure of a patent foramen ovale in a patient with lipomatous hypertrophy of the atrial septum
    H Al-Faleh
    University of Ottawa Heart Institute, Canada
    Can J Cardiol 21:789-90. 2005
    ..The present report discusses a patient who continued to have residual shunting following percutanous closure because of improper seating of the device in the presence of a lipomatous atrial septum...
  32. ncbi request reprint Symptoms in cardiac myxoma
    Nandita Scott
    Chest 124:2408. 2003
  33. pmc The American Heart Association 2007 endocarditis prophylaxis guidelines: a compromise between science and common sense
    John M Embil
    University of Manitoba, Winnipeg, Canada
    Can J Cardiol 24:673-5. 2008
  34. ncbi request reprint Surgical referral in symptomatic mitral regurgitation: greater compliance with guidelines is needed
    Angeline Law
    Eur Heart J 28:1281-2. 2007
  35. ncbi request reprint Prevalence and significance of increased intraventricular velocities in healthy elderly subjects
    Abdulhalim Kinsara
    King Khalid National Guard Hospital, Jeddad, Saudi Arabia
    Can J Cardiol 20:201-3. 2004
    ..Heart murmurs are common in the elderly and increased intracavitary velocities (IIV) within the left ventricle have been reported to be a cause of systolic murmur...