Raja T Abboud

Summary

Affiliation: University of British Columbia
Country: Canada

Publications

  1. ncbi Relationship of matrix metalloproteinase mRNA expression and genetic polymorphisms to emphysema
    Raja T Abboud
    Division of Respiratory Medicine, University of British Columbia, 2775 Heather Street, Vancouver, BC, V5Z 3J5 Canada
    Proc Am Thorac Soc 3:475. 2006
  2. doi Alveolar macrophage proteinase/antiproteinase expression in lung function and emphysema
    Takeo Ishii
    Institute for Heart and Lung Health, St Paul s Hospital, Vancouver, BC
    Eur Respir J 43:82-91. 2014
  3. doi Matrix metalloproteinase expression by human alveolar macrophages in relation to emphysema
    Alison M Wallace
    University of British Columbia UBC James Hogg iCAPTURE Centre, St Paul s Hospital, Vancouver, BC, Canada
    COPD 5:13-23. 2008
  4. pmc Expression of matrix metalloproteinase-1 in alveolar macrophages, type II pneumocytes, and airways in smokers: relationship to lung function and emphysema
    Alison M Wallace
    St Paul s Hospital, University of British Columbia Center for Heart Lung Innovation, 166 1081 Burrard Street, Vancouver, BC, V6Z 1Y6, Canada
    Lung 192:467-72. 2014
  5. pmc Alpha1-antitrypsin deficiency: a clinical-genetic overview
    Raja T Abboud
    Department of Medicine, Respiratory Division, University of British Columbia, Vancouver, BC, Canada
    Appl Clin Genet 4:55-65. 2011
  6. doi Sanger sequencing solved a cryptic case of severe alpha₁-antitrypsin deficiency
    Shing H Zhan
    University of British Columbia, Vancouver, BC, Canada
    Clin Biochem 45:499-501. 2012
  7. ncbi Emphysema in alpha1-antitrypsin deficiency: does replacement therapy affect outcome?
    Raja T Abboud
    Respiratory Division, University of British Columbia, 2775 Heather Street, Vancouver, V5Z 3J5, British Columbia, Canada
    Treat Respir Med 4:1-8. 2005

Collaborators

Detail Information

Publications7

  1. ncbi Relationship of matrix metalloproteinase mRNA expression and genetic polymorphisms to emphysema
    Raja T Abboud
    Division of Respiratory Medicine, University of British Columbia, 2775 Heather Street, Vancouver, BC, V5Z 3J5 Canada
    Proc Am Thorac Soc 3:475. 2006
  2. doi Alveolar macrophage proteinase/antiproteinase expression in lung function and emphysema
    Takeo Ishii
    Institute for Heart and Lung Health, St Paul s Hospital, Vancouver, BC
    Eur Respir J 43:82-91. 2014
    ..We conclude that increased MMP12 and MMP1 expression may play a role in the pathogenesis of emphysema. Cathepsin L and MMP9 may be involved in the development of airflow limitation. ..
  3. doi Matrix metalloproteinase expression by human alveolar macrophages in relation to emphysema
    Alison M Wallace
    University of British Columbia UBC James Hogg iCAPTURE Centre, St Paul s Hospital, Vancouver, BC, Canada
    COPD 5:13-23. 2008
    ..Furthermore, these data provide evidence to support the concept that multiple proteinases, causing both elastin and collagen degradation, are important in the pathogenesis of pulmonary emphysema...
  4. pmc Expression of matrix metalloproteinase-1 in alveolar macrophages, type II pneumocytes, and airways in smokers: relationship to lung function and emphysema
    Alison M Wallace
    St Paul s Hospital, University of British Columbia Center for Heart Lung Innovation, 166 1081 Burrard Street, Vancouver, BC, V6Z 1Y6, Canada
    Lung 192:467-72. 2014
    ..Matrix metalloproteinase-1, also known as interstitial collagenase, has been implicated as a potentially important proteinase in the genesis of chronic obstructive pulmonary disease and, more specifically, emphysema...
  5. pmc Alpha1-antitrypsin deficiency: a clinical-genetic overview
    Raja T Abboud
    Department of Medicine, Respiratory Division, University of British Columbia, Vancouver, BC, Canada
    Appl Clin Genet 4:55-65. 2011
    ..There are over 100 different AAT gene variants; most are rare and only some are associated with clinical disease...
  6. doi Sanger sequencing solved a cryptic case of severe alpha₁-antitrypsin deficiency
    Shing H Zhan
    University of British Columbia, Vancouver, BC, Canada
    Clin Biochem 45:499-501. 2012
    ..In this communication, we describe the investigations of a case of severe AATD in which the AAT levels were well below those expected from the MZ phenotype determined by isoelectric focusing for protease inhibitor type (IEF PI-typing)...
  7. ncbi Emphysema in alpha1-antitrypsin deficiency: does replacement therapy affect outcome?
    Raja T Abboud
    Respiratory Division, University of British Columbia, 2775 Heather Street, Vancouver, V5Z 3J5, British Columbia, Canada
    Treat Respir Med 4:1-8. 2005
    ....