Genomes and Genes
University of Western Ontario
Organization: University of Western Ontario
- Sympathetic neural activation: an ordered affairCraig D Steinback
Neurovascular Research Laboratory, School of Kinesiology, University of Western Ontario, London, ON, Canada
J Physiol 588:4825-36. 2010....
- Effect of rest interval on strength recovery in young and old womenOlga Theou
Graduate Program in Health and Rehabilitation Sciences, Faculty of Health Sciences, University of Western Ontario, Ontario, Canada
J Strength Cond Res 22:1876-81. 2008..The results of the present study are specific to isokinetic testing and training and are more applicable in rehabilitation and research settings. Practitioners should consider age and gender when prescribing rest intervals between sets...
- Transient middle cerebral artery occlusion induces microglial priming in the lumbar spinal cord: a novel model of neuroinflammationKatie Moisse
Cell Biology Research Group, Robarts Research Institute, London, Ontario, Canada
J Neuroinflammation 5:29. 2008..Following permanent occlusion, neuropathological changes - including a robust glial inflammatory response - also occur downstream of the infarct in the spinal cord...
- Endoscopic transnasal repair of a medial wall orbital blow-out fracture using a balloon catheterCorey Moore
Department of Otorhinolaryngology, University of Western Ontario, London, Ontario
J Otolaryngol Head Neck Surg 37:E22-5. 2008
- Health behaviors among adolescents and young adults with congenital heart diseaseGraham J Reid
Department of Psychology, University of Western Ontario, London, Ontario, Canada
Congenit Heart Dis 3:16-25. 2008..Document the frequency of substance use and oral hygiene among adolescents and young adults with moderate to complex congenital heart disease (CHD)...
- U.S. Federal Regulations for emergency research: a practical guide and commentaryAndrew McRae
Department of Emergency Medicine, Queen s University, Kingston, Ontario, Canada
Acad Emerg Med 15:88-97. 2008..It explores the challenges for IRB review listed above, and offers potential solutions to these problems...
- "We grandmothers know plenty": breastfeeding, complementary feeding and the multifaceted role of grandmothers in MalawiRachel Bezner Kerr
Department of Geography, The University of Western Ontario, London, ON, Canada
Soc Sci Med 66:1095-105. 2008..The paper concludes by discussing the challenges of involving grandmothers in health education, and the difficulties of incorporating local knowledge into a medical system that largely rejects it...
- Detection of stratospheric ozone intrusions by windprofiler radarsW K Hocking
Department of Physics and Astronomy, University of Western Ontario, London, Ontario, N6A 3K7 Canada
Nature 450:281-4. 2007....
- Carbon monoxide liberated from carbon monoxide-releasing molecule CORM-2 attenuates inflammation in the liver of septic miceGediminas Cepinskas
Centre for Critical Illness Research, Lawson Health Research Institute, London, Ontario, N6A 4G4, Canada
Am J Physiol Gastrointest Liver Physiol 294:G184-91. 2008....
- The activation of phonological representations by bilinguals while reading silently: evidence from interlingual homophonesCorinne A Haigh
Department of Psychology, University of Western Ontario, London, ON, Canada
J Exp Psychol Learn Mem Cogn 33:623-44. 2007....
- Neonatal immune system activation with lipopolysaccharide enhances behavioural sensitization to the dopamine agonist, quinpirole, in adult female but not male ratsChristine M Tenk
Neuroscience Program and Department of Psychology, University of Western Ontario, London, Ont, Canada N6A 5C2
Brain Behav Immun 21:935-45. 2007..These findings have important implications for the sexually dimorphic development of addictions to both natural and artificial rewards...
- Technical rationality in Schön's reflective practice: dichotomous or non-dualistic epistemological positionElizabeth Anne Kinsella
School of Occupational Therapy, Faculty of Health Sciences, University of Western Ontario, Elborn College, London, Ontario, Canada
Nurs Philos 8:102-13. 2007..In this way, it is proposed that his critique of technical rationality can be interpreted as an attempt to overcome dualistic thinking as it pertains to professional knowledge...
- Costs versus benefits: best possible and best practical treatment regimens for HIVO Krakovska
Department of Applied Mathematics, University of Western Ontario, London, ON, N6A 5B7, Canada
J Math Biol 54:385-406. 2007..We elucidate the dependence of the optimal treatment regimen on the pharmacokinetic parameters of specific antiviral agents...
- Rat PSP94 inhibits the growth and viability of the rat adenocarcinoma cell line PAIII in vitroPeter A Cadieux
Department of Microbiology and Immunology, University of Western Ontario, London, Ontario, Canada
Cancer Invest 24:246-55. 2006..Rat PSP was shown to inhibit the growth and survival of PAIII cells in a dose-dependent manner with > 90 percent reductions in both observed. TUNEL and Annexin-V assays confirmed PAIII cell death to be via apoptosis...
- Dual task performance in a healthy young adult population: results from a symmetric manipulation of task complexity and articulationAlbert Armieri
Health and Rehabilitation Sciences, The University of Western Ontario, London, ON N6G1H1, Canada
Gait Posture 29:346-8. 2009....
- Mouse G-protein gamma3 expression in the developing CNS and neural crest cell derivativesGregory M Kelly
Department Biology, Molecular Genetics Unit, University of Western Ontario, London, ON, Canada
Int J Dev Biol 52:1143-50. 2008..These data indicate that G protein coupled signaling involving gamma3 participates in a number of physiological roles, not only in the CNS, but also in numerous cells derived from the neural crest...
- Sustaining self-regulatory efficacy and psychological outcome expectations for postnatal exercise: effects of a group-mediated cognitive behavioural interventionA G Cramp
Department of Kinesiology, McMaster University, Hamilton, Ontario, Canada
Br J Health Psychol 14:595-611. 2009....
- Efficacy and risk of atrial fibrillation ablation before 45 years of agePeter Leong-Sit
Department of Medicine, London Health Science Hospital, London, Ontario, Canada
Circ Arrhythm Electrophysiol 3:452-7. 2010..This study seeks to characterize the effectiveness and risk of AF ablation in the young...
- Perceptual organization, phonological awareness, and reading comprehension in adults with and without learning disabilitiesMargot Stothers
Faculty of Health Sciences, The University of Western Ontario, London, ON, Canada
Ann Dyslexia 60:209-37. 2010..The study's findings have implications for understanding the reading of adults with learning disabilities, and the nature of reading comprehension in general...
- Evidence from visuomotor adaptation for two partially independent visuomotor systemsLore Thaler
Department of Psychology, Ohio State University, USA
J Exp Psychol Hum Percept Perform 36:924-35. 2010..The findings suggest that the human brain employs 2 partially independent visuomotor systems that rely on different types of visual spatial information...
- The geography of diabetes in London, Canada: the need for local level policy for prevention and managementJordan W Tompkins
Centre for Studies in Family Medicine, Department of Family Medicine, Schulich School of Medicine and Dentistry, The University of Western Ontario, London, ON, Canada
Int J Environ Res Public Health 7:2407-22. 2010..Future endeavours must continue to identify local level trends in order to support policy development, resource planning and care for improved health outcomes and improved equity in access to care across geographic regions...
- The tissue and plasma concentration of polyols and sugars in sheep intrauterine growth retardationTimothy R H Regnault
Department of Pediatrics, University of Colorado Health Sciences Center, Aurora, USA
Exp Biol Med (Maywood) 235:999-1006. 2010..The manner in which these alterations in fetoplacental carbohydrate metabolism contribute to the pathophysiology of PI-IUGR is currently unknown...
- Dietary lipid composition and avian migratory flight performance: Development of a theoretical framework for avian fat storageEdwin R Price
Advanced Facility for Avian Research, Department of Biology, University of Western Ontario, London ON, Canada N6A 5B7
Comp Biochem Physiol A Mol Integr Physiol 157:297-309. 2010..Finally, I develop a theoretical framework for studying the composition of fat stores in migrants, focusing on the tradeoffs between fatty acid transport rates, energy storage, and assimilation during stopover refueling...
- Recent advances in alveolar biology: some new looks at the alveolar interfaceFred Possmayer
University of Western Ontario, Departments of Obstetrics Gynaecology and Biochemistry, London, Ontario, Canada
Respir Physiol Neurobiol 173:S55-64. 2010..This contribution attempts to emphasize how these new approaches have resulted in a fuller appreciation of events presumably occurring at the alveolar interface...
- Bilateral hippocampal stimulation for intractable temporal lobe epilepsy: impact on seizures and memoryRichard S McLachlan
Department of Clinical Neurological Sciences, University of Western Ontario, London, Ontario, Canada
Epilepsia 51:304-7. 2010..No other adverse effects occurred. Seizure frequency is reduced both during and for a period after bilateral hippocampal stimulation, but the overall impact in this study is not as robust as has been previously reported...
- Acute cytomegalovirus cholecystitis following renal transplantationM Drage
Department of Surgery, University of Cambridge, Addenbrooke s Hospital, Cambridge, United Kingdom
Am J Transplant 9:1249-52. 2009..The diagnosis of CMV infection was confirmed in both cases using CMV-specific staining of the gallbladder. The diagnosis of CMV cholecystitis must be considered in all patients with upper abdominal pain after renal transplantation...
- Delayed association of the NADPH oxidase complex with macrophage vacuoles containing the opportunistic pathogen Burkholderia cenocepaciaKaren E Keith
Siebens Drake Research Institute, Department of Microbiology and Immunology, University of Western Ontario, London, ON N6A 5C1, Canada
Microbiology 155:1004-15. 2009..This phenomenon may contribute to preventing the efficient clearance of this opportunistic pathogen from the infected airways of susceptible patients...
- Does exposure to infectious diseases in infancy affect old-age mortality? Evidence from a pre-industrial populationAlain Gagnon
Population Studies Centre, Department of Sociology, University of Western Ontario, London, Canada
Soc Sci Med 68:1609-16. 2009....
- Alcohol-related victimization among young adult Canadian drinkers: the explanatory roles of hazardous drinking and illicit drug useSamantha L Wells
Social Prevention and Health Policy Research Department, Centre for Addiction and Mental Health, 100 Collip Circle, Suite 200, London, ON N6G 4X8
Can J Public Health 100:55-9. 2009....
- The retinoic acid binding protein CRABP2 is increased in murine models of degenerative joint diseaseIan D Welch
Department of Animal Care and Veterinary Services, University of Western Ontario, London, Ontario N6A5C1, Canada
Arthritis Res Ther 11:R14. 2009..In the present study, we examined the expression of a retinoid-regulated gene in murine models of OA...
- From psychiatric ward to the streets and sheltersC Forchuk
School of Nursing, University of Western Ontario, Lawson Health Research Institute, 375 South Street, London, Ontario N6A 4G5, Canada
J Psychiatr Ment Health Nurs 13:301-8. 2006..Without recognition, this problem is at risk of remaining invisible with no further improvements to the situation...
- Surviving the tornado of mental illness: psychiatric survivors' experiences of getting, losing, and keeping housingCheryl Forchuk
School of Nursing, University of Western Ontario, London, Ontario, Canada
Psychiatr Serv 57:558-62. 2006..A caring community response, including adequate housing, income support, and community care, can help people rebuild their lives...
- Collisions and traffic violations of alcohol, cannabis and cocaine abuse clients before and after treatmentScott MacDonald
Centre for Addiction and Mental Health, Suite 200, 100 Collip Circle, London, Ont, Canada N6G 4X8
Accid Anal Prev 36:795-800. 2004..More research is needed to better understand the reasons for the higher risk of traffic events and to determine reasons for declines...
- Effects of early song experience on song preferences and song control and auditory brain regions in female house finches (Carpodacus mexicanus)Alexandra M Hernandez
Department of Psychology, University of Toronto at Mississauga, 3359 Mississauga Rd North, Mississauga ON, Canada L5L 1C6
J Neurobiol 59:247-58. 2004..However, overall greater activation in isolate females in auditory areas suggests that exposure to song early in life may increase the selectivity of Zenk activation to song playback in auditory areas...
- A facilitative approach to learning about curriculum developmentDolly Goldenberg
Faculty of Health Sciences, School of Nursing, The University of Western Ontario, HSA 3a, London, Ontario, Canada N6A 5C1
J Nurs Educ 43:31-5. 2004..This article discusses the strengths and limitations of this pragmatic and productive learning approach to preparing future nurse educators for their role as curriculum developers...
- Characterization of dendritic cells in humans with type 1 diabetesKelly L Summers
John P Robarts Research Institute, London, Ontario N6A 5C1, Canada
Ann N Y Acad Sci 1005:226-9. 2003..These findings provide new insight toward understanding the pathological role of DCs in type 1 diabetes...
- Metallothioneins in human tumors and potential roles in carcinogenesisM George Cherian
Department of Pathology, University of Western Ontario, London, Ont, Canada N6A 5C1
Mutat Res 533:201-9. 2003..Therefore, additional experimental data on MT and its isoforms in human tumors, are needed to elucidate the biological functions of MT during tumor progression, along with other tumor markers...
- Psychiatric and psychological co-morbidity in patients with dermatologic disorders: epidemiology and managementMadhulika A Gupta
Department of Psychiatry, University of Western Ontario, London, Ontario, Canada
Am J Clin Dermatol 4:833-42. 2003..Some dermatology patients are likely to benefit from psychotherapeutic interventions and psychotropic agents for the management of the psychosocial comorbidity, in addition to the standard dermatologic therapies for their skin disorder...
- Spatial memory for food hidden by rats (Rattus norvegicus) on the radial maze: studies of memory for where, what, and whenLeanne R Bird
Department of Psychology, University of Western Ontario, London, Canada
J Comp Psychol 117:176-87. 2003..In Experiment 6, rats chose between arms where cheese and pretzels were hidden,with cheese degraded at one delay interval but not the other. Together, these experiments indicate memory for what and where but not when...
- Phonology and syntax in specific language impairment: evidence from a connectionist modelMarc F Joanisse
Department of Psychology, The University of Western Ontario, London, Ont, Canada N6A 5C2
Brain Lang 86:40-56. 2003..These results are consistent with behavioral data concerning syntactic deficits in SLI. The model provides a causal demonstration of how a perceptual deficit could give rise to grammatical deficits in SLI...
- Activity and expression of progesterone metabolizing 5alpha-reductase, 20alpha-hydroxysteroid oxidoreductase and 3alpha(beta)-hydroxysteroid oxidoreductases in tumorigenic (MCF-7, MDA-MB-231, T-47D) and nontumorigenic (MCF-10A) human breast cancer cellsJohn P Wiebe
Hormonal Regulatory Mechanisms Laboratory, Department of Biology, University of Western Ontario, London, Ontario, Canada N6A 5B7
BMC Cancer 3:9. 2003....
- The effect of resistive breathing on leg muscle oxygenation using near-infrared spectroscopy during exercise in menJohn M Kowalchuk
Department of Physiology, St George s Hospital Medical School, Cranmer Terrance, Tooting, London SW17 0RE, UK
Exp Physiol 87:601-11. 2002..Assuming that leg muscle O2 consumption did not decrease, this implies that leg blood flow was not reduced consequent to a redistribution of flow away from the working leg muscle...
- Pain: a culturally informed experienceDavid Ng
Department of Medicine, University of Western Ontario, London Ontario
Pain Res Manag 7:109-11. 2002
- The probability that beneficial mutations are lost in populations with periodic bottlenecksL M Wahl
Applied Mathematics, University of Western Ontario, London, Canada
Evolution 55:2606-10. 2001..We show that both approaches yield the same approximation for extinction probability. From this, we derive an approximate expression for an effective population size...
- Effect of a maldistribution of microvascular blood flow on capillary O(2) extraction in sepsisChristopher G Ellis
Vascular Biology Program, Lawson Health Research Institute, London Health Sciences Centre, London, Ontario N6B 1B8, Canada
Am J Physiol Heart Circ Physiol 282:H156-64. 2002..Capillary O(2) extraction increased threefold (P < 0.05) and was directly related to the degree of stopped flow in the EDL. Thus impaired O(2) transport in early stage sepsis is likely the result of a microcirculatory dysfunction...
- Haemochromatosis: find them or forget about them?Paul C Adams
Department of Medicine, London Health Sciences Centre, Ontario, Canada
Eur J Gastroenterol Hepatol 16:857-8. 2004..The demonstration of significant liver disease in family members is a strong reminder of the vital importance of pedigree studies when a typical haemochromatosis patient is identified...
- Family cancer histories predictive of a high risk of hereditary non-polyposis colorectal cancer associate significantly with a genomic rearrangement in hMSH2 or hMLH1P J Ainsworth
Molecular Diagnostic Laboratory and Cancer Genetics Unit, London Health Sciences Center, and the University of Western Ontario, London, Ontario, Canada
Clin Genet 66:183-8. 2004..Family cancer histories predictive of a high risk of HNPCC significantly associate with a genomic rearrangement in hMSH2 or hMLH1...
- Delays in the administration of antibiotics are associated with mortality from adult acute bacterial meningitisN Proulx
Departmetn of Medicine, University of Western Ontario, London, Canada
QJM 98:291-8. 2005..Bacterial meningitis continues to cause high mortality. Few studies address the possible association between this mortality and antibiotic administration delays...
- Young children's perceptions of physicians wearing standard precautions versus customary attireJennifer Truong
Child Health Research Institute, Department of Paediatrics, University of Western Ontario, Children s Hospital of Western Ontario, London, Ontario, Canada
Pediatr Emerg Care 22:13-7. 2006..The aim of the study was to determine if young children have a preference regarding whether physicians wear standard precautions attire...
- NeuroecologyDavid F Sherry
Department of Psychology, Program in Neuroscience, University of Western Ontario, London, Ontario, Canada N6A 5C2
Annu Rev Psychol 57:167-97. 2006..The contribution of neuroecology to psychology and the neurosciences is the information it provides on the selective pressures that have influenced the evolution of cognition and brain structure...
- Feasibility of a fast inverse dose optimization algorithm for IMRT via matrix inversion without negative beamlet intensitiesS P Goldman
Department of Physics and Astronomy, University of Western Ontario, London, Ontario N6A 3K7, Canada
Med Phys 32:3007-16. 2005..In conclusion, the new method provides a fast and robust technique to find a global minimum that yields excellent results for the inverse planning of IMRT...
- The effects of lipopolysaccharide and lithium chloride on the ingestion of a bitter-sweet taste: comparing intake and palatabilityShelley K Cross-Mellor
Graduate Program in Neuroscience, Department of Psychology, University of Western Ontario, London, Ont, Canada N6A 5C2
Brain Behav Immun 19:564-73. 2005....
- Use of the preparticipation physical examination form to screen for the female athlete triad in Canadian interuniversity sport universitiesJane S Rumball
Fowler Kennedy Sport Medicine Clinic, University of Western Ontario, London, Ontario, Canada
Clin J Sport Med 15:320-5. 2005..The purpose of this study was to survey universities affiliated with Canadian Interuniversity Sport on existing screening protocols for the female athlete triad, and to identify any potential areas for improvement of this system...
- The involvement of the "fusiform face area" in processing facial expressionTzvi Ganel
CIHR Group on Action and Perception, Department of Psychology, University of Western Ontario, London, Ontario, Canada N6A 5C2
Neuropsychologia 43:1645-54. 2005..These findings suggest an interactive network for the processing of expression and identity, in which information about expression is computed from the unique structure of individual faces...
- Measurement of the elastic modulus of single bacterial cellulose fibers using atomic force microscopyGanesh Guhados
Department of Chemical and Biochemical Engineering, The University of Western Ontario, London, Ontario, Canada
Langmuir 21:6642-6. 2005..This value is considerably higher than previous estimates, obtained by less direct means, of the mechanical strength of individual cellulose fibers...
- Determinants of tetanus toxoid immunization in pregnancy in rural BiharAmardeep Thind
Department of Health Services, UCLA School of Public Health, Room 31 299 CHS, Box 951772, Los Angeles, CA 90095 1772, USA
Trop Doct 35:75-7. 2005..Policy implications of these findings are discussed...
- A psychometric analysis of the patient satisfaction with nursing care quality questionnaire: an actionable approach to measuring patient satisfactionHeather Spence Laschinger
School of Nursing, University of Western Ontario, London, Ontario, Canada
J Nurs Care Qual 20:220-30. 2005..The results of this study yielded actionable, patient-focused results that can be used by managers to address areas requiring improvement...
- Applied neuromonitoring and improving CNS outcomesJohn M Murkin
University of Western Ontario, London, Ontario, Canada
Semin Cardiothorac Vasc Anesth 9:139-42. 2005..Overall patient outcomes can be improved, and hospital length of stay shortened, by applied neuromonitoring techniques...
- What's the difference? Contrasting modular and neural network approaches to understanding developmental variabilityJ Bruce Morton
Department of Psychology, University of Western Ontario, London, Ontario N6A 5C2, Canada
J Dev Behav Pediatr 26:128-39. 2005..The authors conclude that neural network approaches offer more formal and parsimonious accounts of the nature and sources of developmental variability...
- Hexazonium pararosaniline as a fixative for animal tissuesJ A Kiernan
Department of Anatomy and Cell Biology, University of Western Ontario London Canada N6A 5C1
Biotech Histochem 79:203-10. 2004..It is concluded that there is no evidence for a "fixative" action of hexazonium pararosaniline. The protective effect on frozen sections of unfixed tissue is attributable probably to the low pH of the solution...
- Strengthening capacity to limit intrusion: theorizing family health promotion in the aftermath of woman abuseMarilyn Ford-Gilboe
University of Western Ontario, London, Canada
Qual Health Res 15:477-501. 2005..This theory adds to our knowledge of the long-term consequences of IPV for families and provides direction for practice and policy...
- Attenuation of neurologic injury during cardiac surgeryJ M Murkin
Department of Anesthesiology and Perioperative Medicine, London Health Sciences Center, University of Western Ontario, Canada
Ann Thorac Surg 72:S1838-44. 2001..Meta-analysis of the large North American aprotinin database of prospective, randomized, placebo-controlled clinical trials is suggestive of a cerebroprotective potential associated with high-dose aprotinin administration...
- HEALTH/SAFETY IMPACT OF ONTARIOS DRINKING HOURSEvelyn Vingilis; Fiscal Year: 2001..Alcohol-related casualties for both cities will be subjected to time-series analyses. In addition, Detroit data will be disaggregated to analyze the trends of alcohol-related casualties involving Ontario drivers. ..
- EVALUATING A INTERVENTION TO REDUCE BARROOM AGGRESSIONKathryn Graham; Fiscal Year: 2002..abstract_text> ..
- DEVELOPMENT OF fMRI COMPATIBLE REVERSIBLE DEACTIVATIONSTEPHEN LOMBER; Fiscal Year: 2005..Such a development should have wide appeal and will greatly advance our ability to dissect functional circuits with fMRI. ..
- CEREBRAL ORGANIZATION FOLLOWING COCHLEAR IMPLANTSTEPHEN LOMBER; Fiscal Year: 2005..The results from these studies will be directly applicable to clinical situations concerning the functional outcomes of cochlear implants in young children. ..
- Cryopreservation of the model organism Drosophila melanogasterBRENT SINCLAIR; Fiscal Year: 2007..The ultimate goal is to cryopreserve D. melanogaster, an achievement that will greatly increase the utility of the Drosophila model for human disease research. ..