J Li

Summary

Affiliation: The Hospital for Sick Children
Country: Canada

Publications

  1. ncbi Comparison of the profiles of postoperative systemic hemodynamics and oxygen transport in neonates after the hybrid or the Norwood procedure: a pilot study
    Jia Li
    Division of Cardiology, The Hospital for Sick Children, 555 University Avenue, Toronto, Ontario, Canada, M5G 1X8
    Circulation 116:I179-87. 2007
  2. ncbi Systemic and myocardial oxygen transport responses to brain death in pigs
    J Li
    Division of Cardiology, The Hospital for Sick Children, Toronto, Ontario, Canada
    Transplant Proc 39:21-6. 2007
  3. doi The influence of systemic hemodynamics and oxygen transport on cerebral oxygen saturation in neonates after the Norwood procedure
    Jia Li
    Heart Center, The Hospital for Sick Children, Toronto, Ontario, Canada
    J Thorac Cardiovasc Surg 135:83-90, 90.e1-2. 2008
  4. doi Energy expenditure and caloric and protein intake in infants following the Norwood procedure
    Jia Li
    Cardiac Program, The Hospital for Sick Children, Toronto, Ontario, Canada
    Pediatr Crit Care Med 9:55-61. 2008
  5. doi Significant correlation of comprehensive Aristotle score with total cardiac output during the early postoperative period after the Norwood procedure
    Jia Li
    The Labbatt Family Heart Center, The Hospital for Sick Children, Toronto, Ontario, Canada
    J Thorac Cardiovasc Surg 136:123-8. 2008
  6. pmc Assessment of the relationship between cerebral and splanchnic oxygen saturations measured by near-infrared spectroscopy and direct measurements of systemic haemodynamic variables and oxygen transport after the Norwood procedure
    J Li
    The Cardiac Program, The Hospital for Sick Children, Toronto, Ontario, Canada
    Heart 92:1678-85. 2006
  7. ncbi DQCAR microsatellite polymorphism and susceptibility to rheumatoid arthritis
    D P Singal
    Department of Pathology, McMaster University, Hamilton, Ontario, Canada
    Tissue Antigens 51:613-7. 1998
  8. ncbi Profiles of hemodynamics and oxygen transport derived by using continuous measured oxygen consumption after the Norwood procedure
    Jia Li
    Cardiac Program, The Hospital for Sick Children, Toronto, Ontario, Canada
    J Thorac Cardiovasc Surg 133:441-8. 2007
  9. doi The porcine gut microbial metagenomic library for mining novel cellulases established from growing pigs fed cellulose-supplemented high-fat diets
    W Wang
    Department of Animal and Poultry Science, University of Guelph, Guelph, Ontario, Canada
    J Anim Sci 90:400-2. 2012
  10. doi Carbon dioxide--a complex gas in a complex circulation: its effects on systemic hemodynamics and oxygen transport, cerebral, and splanchnic circulation in neonates after the Norwood procedure
    Jia Li
    The Heart Center, Hospital for Sick Children, Toronto, Ontario, Canada
    J Thorac Cardiovasc Surg 136:1207-14. 2008

Collaborators

Detail Information

Publications55

  1. ncbi Comparison of the profiles of postoperative systemic hemodynamics and oxygen transport in neonates after the hybrid or the Norwood procedure: a pilot study
    Jia Li
    Division of Cardiology, The Hospital for Sick Children, 555 University Avenue, Toronto, Ontario, Canada, M5G 1X8
    Circulation 116:I179-87. 2007
    ....
  2. ncbi Systemic and myocardial oxygen transport responses to brain death in pigs
    J Li
    Division of Cardiology, The Hospital for Sick Children, Toronto, Ontario, Canada
    Transplant Proc 39:21-6. 2007
    ..Brain death is associated with profound disturbances of systemic and myocardial oxygen transport, but little is known regarding the acute response of systemic oxygen consumption (VO(2))...
  3. doi The influence of systemic hemodynamics and oxygen transport on cerebral oxygen saturation in neonates after the Norwood procedure
    Jia Li
    Heart Center, The Hospital for Sick Children, Toronto, Ontario, Canada
    J Thorac Cardiovasc Surg 135:83-90, 90.e1-2. 2008
    ..Ischemic brain injury is an important morbidity in neonates after the Norwood procedure. Its relationship to systemic hemodynamic oxygen transport is poorly understood...
  4. doi Energy expenditure and caloric and protein intake in infants following the Norwood procedure
    Jia Li
    Cardiac Program, The Hospital for Sick Children, Toronto, Ontario, Canada
    Pediatr Crit Care Med 9:55-61. 2008
    ..Energy requirements of these patients have not been well studied. We assessed energy expenditure and caloric and protein intake during the first 3 days following the Norwood procedure...
  5. doi Significant correlation of comprehensive Aristotle score with total cardiac output during the early postoperative period after the Norwood procedure
    Jia Li
    The Labbatt Family Heart Center, The Hospital for Sick Children, Toronto, Ontario, Canada
    J Thorac Cardiovasc Surg 136:123-8. 2008
    ..An important factor leading to postoperative morbidity and mortality is low cardiac output. We studied the correlation between the comprehensive Aristotle score and cardiac output (CO) in infants after the Norwood procedure...
  6. pmc Assessment of the relationship between cerebral and splanchnic oxygen saturations measured by near-infrared spectroscopy and direct measurements of systemic haemodynamic variables and oxygen transport after the Norwood procedure
    J Li
    The Cardiac Program, The Hospital for Sick Children, Toronto, Ontario, Canada
    Heart 92:1678-85. 2006
    ..To evaluate the clinical utility of near-infrared spectroscopic (NIRS) monitoring of cerebral (ScO2) and splanchnic (SsO2) oxygen saturations for estimation of systemic oxygen transport after the Norwood procedure...
  7. ncbi DQCAR microsatellite polymorphism and susceptibility to rheumatoid arthritis
    D P Singal
    Department of Pathology, McMaster University, Hamilton, Ontario, Canada
    Tissue Antigens 51:613-7. 1998
    ..Analysis of the data suggested that DRB1 genes sharing the QKRAA/QRRAA epitope have the primary association with disease susceptibility and DQCAR alleles do not provide an additional risk for the development of RA...
  8. ncbi Profiles of hemodynamics and oxygen transport derived by using continuous measured oxygen consumption after the Norwood procedure
    Jia Li
    Cardiac Program, The Hospital for Sick Children, Toronto, Ontario, Canada
    J Thorac Cardiovasc Surg 133:441-8. 2007
    ..We used measured oxygen consumption to characterize hemodynamics and oxygen transport after the classic Norwood procedure...
  9. doi The porcine gut microbial metagenomic library for mining novel cellulases established from growing pigs fed cellulose-supplemented high-fat diets
    W Wang
    Department of Animal and Poultry Science, University of Guelph, Guelph, Ontario, Canada
    J Anim Sci 90:400-2. 2012
    ....
  10. doi Carbon dioxide--a complex gas in a complex circulation: its effects on systemic hemodynamics and oxygen transport, cerebral, and splanchnic circulation in neonates after the Norwood procedure
    Jia Li
    The Heart Center, Hospital for Sick Children, Toronto, Ontario, Canada
    J Thorac Cardiovasc Surg 136:1207-14. 2008
    ..We sought to quantitatively define the effects of stepwise increases in arterial carbon dioxide tension on systemic oxygen transport and cerebral and splanchnic circulation after the Norwood procedure...
  11. ncbi An analysis of oxygen consumption and oxygen delivery in euthermic infants after cardiopulmonary bypass with modified ultrafiltration
    Jia Li
    Division of Cardiology, Hospital for Sick Children, Toronto, Ontario, Canada
    Ann Thorac Surg 78:1389-96. 2004
    ..We sought to assess VO2 and DO2 and their relationship with proinflammatory cytokines after CPB with the use of modified ultrafiltration (MUF) in infants...
  12. ncbi D6S273 microsatellite polymorphism and susceptibility to rheumatoid arthritis
    D P Singal
    Department of Pathology, McMaster University, Hamilton, Ontario, Canada
    Tissue Antigens 52:353-8. 1998
    ..The D6S273 138 allele thus provides an additional risk in RA susceptibility. The results in the present study therefore suggest that two regions in MHC, DRB1 and D6S273, contribute to susceptibility to RA...
  13. doi Effect of inhaled hydrogen sulfide on metabolic responses in anesthetized, paralyzed, and mechanically ventilated piglets
    Jia Li
    Cardiac Program, Hospital for Sick Children, Toronto, Ontario, Canada
    Pediatr Crit Care Med 9:110-2. 2008
    ..We conducted a preclinical study to explore the potential effect of H2S on metabolic rate in large mammals...
  14. ncbi Initial experience with hybrid palliation for neonates with single-ventricle physiology
    Christopher A Caldarone
    Division of Cardiovascular Surgery, Department of Pediatrics, University of Toronto, The Hospital for Sick Children, Toronto, Ontario, Canada
    Ann Thorac Surg 84:1294-300. 2007
    ..Hybrid palliation consisting of bilateral pulmonary artery banding and ductal stenting (PAB/DS) is an emerging method to palliate neonates with functional single ventricles...
  15. ncbi Insulin-like growth factor 1 improves the relationship between systemic oxygen consumption and delivery in piglets after cardiopulmonary bypass
    Jia Li
    Division of Cardiology, Hospital for Sick Children, Toronto, Ontario, Canada
    J Thorac Cardiovasc Surg 127:1436-41. 2004
    ..We sought to assess the effects of insulin-like growth factor 1 on the balance between systemic oxygen consumption and oxygen delivery after cardiopulmonary bypass in piglets...
  16. ncbi Inclusion of oxygen consumption improves the accuracy of arterial and venous oxygen saturation interpretation after the Norwood procedure
    Jia Li
    Cardiac Program, The Hospital for Sick Children, Toronto, Ontario, Canada
    J Thorac Cardiovasc Surg 131:1099-107. 2006
    ..We sought to examine the correlation of the indirect indicators to VO2-derived measures of oxygen transport...
  17. ncbi Adverse effects of dopamine on systemic hemodynamic status and oxygen transport in neonates after the Norwood procedure
    Jia Li
    Cardiac Program, The Hospital for Sick Children, Toronto, Ontario, Canada
    J Am Coll Cardiol 48:1859-64. 2006
    ..The purpose of this study was to evaluate the effects of dopamine on hemodynamic status and oxygen transport in neonates after the Norwood procedure...
  18. ncbi The effects of carbon dioxide on oxygenation and systemic, cerebral, and pulmonary vascular hemodynamics after the bidirectional superior cavopulmonary anastomosis
    Aparna Hoskote
    Department of Critical Care Medicine, The Hospital for Sick Children, Toronto, Canada
    J Am Coll Cardiol 44:1501-9. 2004
    ..We investigated the effects of different CO(2) tensions on oxygenation, pulmonary blood flow (Qp), cerebral blood flow, and systemic blood flow (Qs) after the bidirectional superior cavopulmonary anastomosis (BCPA)...
  19. doi Epidermal growth factor-expressing Lactococcus lactis enhances growth performance of early-weaned pigs fed diets devoid of blood plasma
    A Bedford
    Department of Animal and Poultry Science, University of Guelph, Guelph, Ontario, Canada
    J Anim Sci 90:4-6. 2012
    ..64). These results indicate that supplementation with EGF-LL can be effective in enhancing the performance of early-weaned piglets fed a low complexity diet and reduces the need for feeding high-quality animal proteins and antibiotics...
  20. ncbi Continuous measurement of oxygen consumption during cardiopulmonary bypass: description of the method and in vivo observations
    Jia Li
    Division of Cardiology, Hospital for Sick Children, Toronto, Ontario, Canada
    Ann Thorac Surg 77:1671-7. 2004
    ..We aimed to develop a noninvasive method to continuously measure oxygen consumption using respiratory mass spectrometry during hypothermic cardiopulmonary bypass in pigs...
  21. ncbi Evidence for a significant myocardial contribution to total metabolic burden during hypothermic cardiopulmonary bypass: a study of continuously measured oxygen consumption and arterial lactate levels in pigs
    Jia Li
    Division of Cardiology, Hospital for Sick Children, Toronto, Ontario, Canada
    Perfusion 20:277-83. 2005
    ..We assessed the causes of imbalance of oxygen transport by continuously measuring oxygen consumption (VO2) during hypothermic cardiopulmonary bypass (CPB) in pigs...
  22. ncbi Effect of carbon dioxide on systemic oxygenation, oxygen consumption, and blood lactate levels after bidirectional superior cavopulmonary anastomosis
    Jia Li
    Division of Cardiology, The Hospital for Sick Children, Toronto, Ontario, Canada
    Crit Care Med 33:984-9. 2005
    ..We sought to assess the effects of four different CO2 tensions on systemic oxygenation, oxygen consumption, and arterial blood lactate levels early after bidirectional superior cavopulmonary anastomosis...
  23. pmc Neuroplasticity-dependent and -independent mechanisms of chronic deep brain stimulation in stressed rats
    F R Bambico
    Research Imaging Centre, Centre for Addiction and Mental Health, Toronto, ON, Canada
    Transl Psychiatry 5:e674. 2015
    ..Taken together, our findings suggest that neuroplastic changes, including neurogenesis, may be involved in specific anxiolytic effects of DBS without affecting its general antidepressant-like response...
  24. ncbi NRAMP1 gene polymorphisms in patients with rheumatoid arthritis
    D P Singal
    Department of Pathology and Molecular Medicine, McMaster University, Hamilton, Ontario, Canada
    Tissue Antigens 55:44-7. 2000
    ....
  25. ncbi Arterial elastase activity after balloon angioplasty and effects of elafin, an elastase inhibitor
    A W Barolet
    Terrence Donnelly Heart Centre, Division of Cardiology, St. Michael's Hospital, Toronto, Ontario, Canada M5B 1W8
    Arterioscler Thromb Vasc Biol 21:1269-74. 2001
    ..05). These data suggest that an early increase in serine elastase activity after BA contributes to intimal hyperplasia. Serine elastase inhibition may be a potential therapeutic approach to inhibit intimal hyperplasia...
  26. doi Antidiabetic effects of duodenojejunal bypass in an experimental model of diabetes induced by a high-fat diet
    M Woods
    Children s Health Research Institute, University of Western Ontario, London, Ontario, Canada
    Br J Surg 98:686-96. 2011
    ..This study characterized pancreatic islet and duodenojejunal enteroendocrine cells in normal mice and those with diabetes induced by a high-fat diet (HFD) following duodenojejunal bypass (DJB)...
  27. ncbi Integrated system for high-throughput protein identification using a microfabricated device coupled to capillary electrophoresis/nanoelectrospray mass spectrometry
    J Li
    Institute for Biological Sciences, Ottawa, Ontario, Canada
    Proteomics 1:975-86. 2001
    ....
  28. ncbi Monitoring the fate of methoprene larvicide for West Nile virus management
    J Li
    Department of Civil Engineering, Ryerson University, 350 Victoria Street, Toronto, Ontario M5B 2K3, Canada
    Water Sci Technol 54:395-402. 2006
    ....
  29. ncbi Doppler tissue imaging in the assessment of atrioventricular conduction time: validation of a novel technique and comparison with electrophysiologic and pulsed wave Doppler-derived equivalents in an animal model
    Masaki Nii
    Division of Cardiology, The Hospital for Sick Children, University of Toronto, Toronto, Ontario, Canada
    J Am Soc Echocardiogr 19:314-21. 2006
    ..05). Pre-ejection period prolonged with faster HR (P < .001), unlike electromechanical delay. In conclusion, DTI allows more accurate measurement of AVCT over a wider HR range than does PD...
  30. ncbi Remote ischemic preconditioning of the recipient reduces myocardial ischemia-reperfusion injury of the denervated donor heart via a Katp channel-dependent mechanism
    Igor E Konstantinov
    Division of Cardiovascular Surgery, Hospital for Sick Children, 555 University Avenue, Toronto, Ontario, Canada M5G 1X8
    Transplantation 79:1691-5. 2005
    ....
  31. ncbi A simple surgical technique for interventional transcatheter completion of the total cavopulmonary connection
    Igor E Konstantinov
    Division of Cardiovascular Surgery, Hospital for Sick Children, Toronto, Ontario, Canada
    J Thorac Cardiovasc Surg 129:210-2. 2005
  32. ncbi Early gene expression profiles during intraoperative myocardial ischemia-reperfusion in cardiac surgery
    Sara Arab
    Richard Lewar Centre of Excellence, Toronto General Hospital, University of Toronto, Toronto, Canada
    J Thorac Cardiovasc Surg 134:74-81, 81.e1-2. 2007
    ..We tested the hypothesis that intraoperative ischemia-reperfusion under conditions of blood cardioplegic arrest would induce a unique myocardial genomic profile indicative of a cardioprotective response...
  33. ncbi Atrioventricular discordance with ventriculoarterial concordance: A remaining indication for the atrial switch operation
    Igor E Konstantinov
    Division of Cardiovascular Surgery, Hospital for Sick Children, University of Toronto, 555 University Avenue, Toronto, Ontario, Canada
    J Thorac Cardiovasc Surg 128:944-5. 2004
  34. ncbi Randomized controlled trial of the effects of remote ischemic preconditioning on children undergoing cardiac surgery: first clinical application in humans
    Michael M H Cheung
    Division of Cardiology and Cardiovascular Surgery, Hospital for Sick Children, Toronto, Canada
    J Am Coll Cardiol 47:2277-82. 2006
    ..We conducted a randomized controlled trial of the effects of remote ischemic preconditioning (RIPC) in children undergoing repair of congenital heart defects...
  35. ncbi Assumed oxygen consumption in the determination of cardiac output in children after cardiac surgery
    Jia Li
    J Thorac Cardiovasc Surg 131:251; author reply 252. 2006
  36. ncbi Intravenous sildenafil is a potent pulmonary vasodilator in children with congenital heart disease
    Ingram Schulze-Neick
    Abteilung für Angeborene Herzfehler, Deutsches Herzzentrum Berlin, Berlin, Germany
    Circulation 108:II167-73. 2003
    ..This study compares the effects of inhaled NO before and after the specific inhibition of the PDE-5 by intravenous sildenafil (Viagra) in pre- and postoperative children with increased PVR because of CHD...
  37. ncbi The endothelin antagonist BQ123 reduces pulmonary vascular resistance after surgical intervention for congenital heart disease
    Ingram Schulze-Neick
    Cardiac Intensive Care Unit, Department of Vascular Biology and Pharmacology, and Cardiothoracic Unit, Great Ormond Street Hospital, London, United Kingdom
    J Thorac Cardiovasc Surg 124:435-41. 2002
    ....
  38. ncbi Measured versus estimated oxygen consumption in ventilated patients with congenital heart disease: the validity of predictive equations
    Jia Li
    Department of Cardiology, Great Ormond Street Hospital, London, UK
    Crit Care Med 31:1235-40. 2003
    ..To determine the validity of predictive equations in calculating oxygen consumption (Vo(2)) in ventilated patients with congenital heart disease...
  39. ncbi Noninvasive assessment of left ventricular force-frequency relationships using tissue Doppler-derived isovolumic acceleration: validation in an animal model
    Michael Vogel
    Cardiothoracic Unit, Great Ormond Street Hospital for Children, NHS Trust, London, UK
    Circulation 107:1647-52. 2003
    ..In this study, we assessed the usefulness of IVA to measure left ventricular (LV) contractile function and force-frequency relationships in an experimental preparation...
  40. pmc Neurofibromin regulates somatic growth through the hypothalamic-pituitary axis
    Balazs Hegedus
    Department of Neurology, Washington University School of Medicine, St Louis, MO 63110, USA
    Hum Mol Genet 17:2956-66. 2008
    ..Collectively, these data demonstrate a critical role for neurofibromin in hypothalamic-pituitary axis function and provide further insights into the short stature and GH deficits seen in children with NF1...
  41. ncbi Isovolumic but not ejection phase Doppler tissue indices detect left ventricular dysfunction caused by coronary stenosis
    Mikiko Shimizu
    Division of Cardiology, Hospital for Sick Children, Toronto, Ontario, Canada
    J Am Soc Echocardiogr 18:1241-6. 2005
    ..IVA also has the ability to describe the force-frequency relationship during incremental atrial pacing in vivo...
  42. ncbi The remote ischemic preconditioning stimulus modifies gene expression in mouse myocardium
    Igor E Konstantinov
    Division of Cardiovascular Surgery, The Hospital for Sick Children, University of Toronto, Toronto, Ontario, Canada
    J Thorac Cardiovasc Surg 130:1326-32. 2005
    ..We tested the hypothesis that remote ischemic preconditioning modifies myocardial gene expression immediately after the remote ischemic preconditioning stimulus (early phase) and 24 hours later (late phase)...
  43. ncbi Genetic determinants of plasma HDL-cholesterol levels in familial hypercholesterolemia
    Emily S van Aalst-Cohen
    Department of Vascular Medicine, Academic Medical Center, Amsterdam, The Netherlands
    Eur J Hum Genet 13:1137-42. 2005
    ....
  44. doi Corosolic acid stimulates glucose uptake via enhancing insulin receptor phosphorylation
    Lei Shi
    National Center for Drug Screening, People s Republic of China
    Eur J Pharmacol 584:21-9. 2008
    ..Furthermore, Corosolic acid inhibits the enzymatic activities of several diabetes-related non-receptor protein tyrosine phosphatases (PTPs) in vitro, such as PTP1B, T-cell-PTP, src homology phosphatase-1 and src homology phosphatase-2...
  45. pmc Small molecule antagonizes autoinhibition and activates AMP-activated protein kinase in cells
    Tao Pang
    National Center for Drug Screening, Shanghai Institute of Materia Medica, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences and Roche R and D Center China Ltd, Shanghai 201203, China
    J Biol Chem 283:16051-60. 2008
    ..This compound highlights the effort to discover novel AMPK activators and can be a useful tool for elucidating the mechanism responsible for conformational change and autoinhibitory regulation of AMPK...
  46. doi Reduced cardiotropic response to insulin in spontaneously hypertensive rats: role of peroxisome proliferator-activated receptor-gamma-initiated signaling
    Haifeng Zhang
    Department of Physiology, Xijing Hospital, Fourth Military Medical University, Xi an, China
    J Hypertens 26:560-9. 2008
    ..The present study aimed to determine whether hypertension-associated myocardial insulin resistance exists, in addition to any underlying mechanism...
  47. ncbi Association of endothelial nitric oxide synthase genotypes with bone mineral density, bone loss, hip structure, and risk of fracture in older women: the SOF study
    Brent C Taylor
    Center for Chronic Disease Outcomes Research 152 2E, Minneapolis VA Medical Center, and Division of Epidemiology and Community Health, University of Minnesota, Minneapolis, MN 55455, USA
    Bone 39:174-80. 2006
    ..Confirmation of these findings is needed in other populations and with additional markers within and flanking the NOS3 gene region...
  48. ncbi A tribute to Giancarlo Rastelli
    Igor E Konstantinov
    Division of Cardiovascular Surgery, Hospital for Sick Children, Toronto, Ontario, Canada
    Ann Thorac Surg 79:1819-23. 2005
    ..Rastelli lived a short, yet fascinating life. His work was ahead of its time and laid the foundation for the treatment of complex congenital cardiac anomalies...
  49. ncbi Study on the interaction between DNA and protein induced by anticancer drug carboplatin
    Shanchao Liu
    State Key Laboratory of Chemo Biosensing and Chemometrics, College of Chemistry and Chemical Engineering, Hunan University, Changsha 410082, PR China
    J Biochem Biophys Methods 63:125-36. 2005
    ..895 mg/ml(-1) s(-1), 4.7 x 10(-5) s(-1) and 4.03 x 10(4) (mg/ml)-1, respectively. Furthermore, cyclic voltammetry (CV) and electrochemical AC impedance techniques were employed to testify the cross-linking process...
  50. ncbi Berberine-stimulated glucose uptake in L6 myotubes involves both AMPK and p38 MAPK
    Zhe Cheng
    National Center for Drug Screening, Shanghai Institute of Materia Medica, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai 201203, P R China
    Biochim Biophys Acta 1760:1682-9. 2006
    ..These results suggest that berberine circumvents insulin signaling pathways and stimulates glucose uptake through the AMP-AMPK-p38 MAPK pathway, which may account for the antihyperglycemic effects of this drug...
  51. pmc A human novel gene DERPC on 16q22.1 inhibits prostate tumor cell growth and its expression is decreased in prostate and renal tumors
    Mei Sun
    Center for Prostate Disease Research, Deaprtment of Surgery, Uniformed Services University of the Health Sciences, Rockville, MD, USA
    Mol Med 8:655-63. 2002
    ..However, the specific tumor suppressor genes residing in this region need better definition and characterization...
  52. ncbi [Evaluation of operation and anesthesia on hemodynamic variables in patients undergoing elective abdominal surgery by noninvasive thoracic bioimpedance technique]
    Hong Chen
    Department of General Surgery, Xuanwu Hospital, Capital University of Medical Sciences, Beijing 100053, China
    Zhongguo Wei Zhong Bing Ji Jiu Yi Xue 16:172-4. 2004
    ..To analyse and discuss the effects of elective abdominal operation and anaesthesia on patients' cardiac output via noninvasive thoracic bioimpedance technique...
  53. ncbi Genetic determinants of cardiovascular disease risk in familial hypercholesterolemia
    Angelique C M Jansen
    Department of Vascular Medicine, Academic Medical Center, Amsterdam, The Netherlands
    Arterioscler Thromb Vasc Biol 25:1475-81. 2005
    ..To investigate the contribution of polymorphisms in multiple candidate genes to cardiovascular disease (CVD) risk in a large cohort of patients with heterozygous familial hypercholesterolemia (FH)...
  54. ncbi Doppler tissue echocardiography: can transesophageal echocardiography be used to acquire functional data?
    Michael M H Cheung
    Division of Cardiology, Hospital for Sick Children, Toronto, Ontario, Canada
    J Am Soc Echocardiogr 16:732-7. 2003
    ..To date there is no direct comparison of transesophageal and transthoracic Doppler tissue data in patients with cardiac malposition. We compared data acquired from both methods in an animal model...
  55. ncbi Selective inhibition of matrix metalloproteinase isozymes and in vivo protection against emphysema by substituted gamma-keto carboxylic acids
    Dawei Ma
    State Key Laboratory of Bioorganic and Natural Products Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai 200032, China
    J Med Chem 49:456-8. 2006
    ..Among nine MMP isozymes tested, compound 1j displays selective inhibition of MMP-2, -9, and -12 with IC(50) values between 0.20 and 1.51 microuM, and in male golden Syrian hamsters, it shows protection against PPE-induced emphysema...