Edward J Hickey

Summary

Affiliation: The Hospital for Sick Children
Country: Canada

Publications

  1. doi request reprint NASA Model of "Threat and Error" in Pediatric Cardiac Surgery: Patterns of Error Chains
    Edward Hickey
    Division of Cardiovascular Surgery, The Hospital for Sick Children, Toronto, Ontario, Canada Electronic address
    Ann Thorac Surg . 2016
  2. doi request reprint National Aeronautics and Space Administration "threat and error" model applied to pediatric cardiac surgery: error cycles precede ∼85% of patient deaths
    Edward J Hickey
    Divisions of Cardiovascular Surgery and Cardiology, Labatt Family Heart Centre, The Hospital for Sick Children, Toronto, Canada Electronic address
    J Thorac Cardiovasc Surg 149:496-505; discussion 505-7. 2015
  3. doi request reprint Functional health status in adult survivors of operative repair of tetralogy of fallot
    Edward J Hickey
    Division of Cardiovascular Surgery, Department of Surgery, University of Toronto, Hospital for Sick Children, Toronto, Ontario, Canada
    Am J Cardiol 109:873-80. 2012
  4. doi request reprint Left ventricular hypoplasia: a spectrum of disease involving the left ventricular outflow tract, aortic valve, and aorta
    Edward J Hickey
    Division of Cardiovascular Surgery, Department of Surgery, University of Toronto, Hospital for Sick Children, Toronto, Ontario, Canada
    J Am Coll Cardiol 59:S43-54. 2012
  5. pmc A saphenous vein graft aneurysm with fistula development to the right atrium: surgical management of a rare bypass graft complication
    Edward J Hickey
    The Hospital for Sick Children, Ontario, Canada
    Can J Cardiol 24:915-6. 2008
  6. doi request reprint Very low-birth-weight infants with congenital cardiac lesions: is there merit in delaying intervention to permit growth and maturation?
    Edward J Hickey
    Division of Cardiovascular Surgery, Department of Surgery, University of Toronto, The Hospital for Sick Children, Toronto, Ontario, Canada
    J Thorac Cardiovasc Surg 143:126-36, 136.e1. 2012
  7. ncbi request reprint Subcoronary allograft aortic valve replacement: parametric risk-hazard outcome analysis to a minimum of 20 years
    Edward Hickey
    Wessex Cardiothoracic Centre, Southampton, United Kingdom
    Ann Thorac Surg 84:1564-70. 2007
  8. ncbi request reprint Constrictive pericarditis after left extrapleural pneumonectomy and radiotherapy for malignant mesothelioma
    Edward J Hickey
    The Hospital for Sick Children, Toronto, Ontario, Canada
    J Thorac Oncol 2:673-5. 2007
  9. ncbi request reprint Hypoxemic reperfusion exacerbates the neurological injury sustained during neonatal deep hypothermic circulatory arrest: a model of cyanotic surgical repair
    Edward J Hickey
    Oregon Health Science University, Portland, Oregon, USA
    Eur J Cardiothorac Surg 31:906-14. 2007
  10. ncbi request reprint Hawley H. Seiler Resident Award paper. The use of a miniaturized circuit and bloodless prime to avoid cerebral no-reflow after neonatal cardiopulmonary bypass
    Edward Hickey
    Oregon Health and Sciences University, Portland, Oregon, USA
    Ann Thorac Surg 83:895-901. 2007

Collaborators

Detail Information

Publications39

  1. doi request reprint NASA Model of "Threat and Error" in Pediatric Cardiac Surgery: Patterns of Error Chains
    Edward Hickey
    Division of Cardiovascular Surgery, The Hospital for Sick Children, Toronto, Ontario, Canada Electronic address
    Ann Thorac Surg . 2016
    ..All admissions are considered flights, which should pass through stepwise deescalations in risk during surgical recovery. We hypothesized that errors significantly influence risk deescalation and contribute to poor outcomes...
  2. doi request reprint National Aeronautics and Space Administration "threat and error" model applied to pediatric cardiac surgery: error cycles precede ∼85% of patient deaths
    Edward J Hickey
    Divisions of Cardiovascular Surgery and Cardiology, Labatt Family Heart Centre, The Hospital for Sick Children, Toronto, Canada Electronic address
    J Thorac Cardiovasc Surg 149:496-505; discussion 505-7. 2015
    ....
  3. doi request reprint Functional health status in adult survivors of operative repair of tetralogy of fallot
    Edward J Hickey
    Division of Cardiovascular Surgery, Department of Surgery, University of Toronto, Hospital for Sick Children, Toronto, Ontario, Canada
    Am J Cardiol 109:873-80. 2012
    ..Efforts to limit ventricular and outflow tract dysfunction may translate into improved late functional status...
  4. doi request reprint Left ventricular hypoplasia: a spectrum of disease involving the left ventricular outflow tract, aortic valve, and aorta
    Edward J Hickey
    Division of Cardiovascular Surgery, Department of Surgery, University of Toronto, Hospital for Sick Children, Toronto, Ontario, Canada
    J Am Coll Cardiol 59:S43-54. 2012
    ....
  5. pmc A saphenous vein graft aneurysm with fistula development to the right atrium: surgical management of a rare bypass graft complication
    Edward J Hickey
    The Hospital for Sick Children, Ontario, Canada
    Can J Cardiol 24:915-6. 2008
    ..Surgery was successful and the patient was discharged symptom-free one week later...
  6. doi request reprint Very low-birth-weight infants with congenital cardiac lesions: is there merit in delaying intervention to permit growth and maturation?
    Edward J Hickey
    Division of Cardiovascular Surgery, Department of Surgery, University of Toronto, The Hospital for Sick Children, Toronto, Ontario, Canada
    J Thorac Cardiovasc Surg 143:126-36, 136.e1. 2012
    ..Low birth weight and prematurity and are known risks for mortality in congenital heart lesions. It is not known whether risks of delayed intervention are offset by benefits of growth and maturation. We explored this question...
  7. ncbi request reprint Subcoronary allograft aortic valve replacement: parametric risk-hazard outcome analysis to a minimum of 20 years
    Edward Hickey
    Wessex Cardiothoracic Centre, Southampton, United Kingdom
    Ann Thorac Surg 84:1564-70. 2007
    ..We report follow-up to 30 years of patients from a single unit who underwent aortic valve replacement with aortic allografts sterilized in antibiotics and refrigerated at 4 degrees C...
  8. ncbi request reprint Constrictive pericarditis after left extrapleural pneumonectomy and radiotherapy for malignant mesothelioma
    Edward J Hickey
    The Hospital for Sick Children, Toronto, Ontario, Canada
    J Thorac Oncol 2:673-5. 2007
    ..Furthermore, these complications emphasize the importance of trials such as the Mesothelioma and Radical Surgery (MARS) study...
  9. ncbi request reprint Hypoxemic reperfusion exacerbates the neurological injury sustained during neonatal deep hypothermic circulatory arrest: a model of cyanotic surgical repair
    Edward J Hickey
    Oregon Health Science University, Portland, Oregon, USA
    Eur J Cardiothorac Surg 31:906-14. 2007
    ..In particular, the vasodilatation that elevates cerebral blood flow (CBF) in response to hypoxemia is absent. This study therefore aimed to investigate whether post-CPB hypoxemia exacerbates brain injury resulting from DHCA...
  10. ncbi request reprint Hawley H. Seiler Resident Award paper. The use of a miniaturized circuit and bloodless prime to avoid cerebral no-reflow after neonatal cardiopulmonary bypass
    Edward Hickey
    Oregon Health and Sciences University, Portland, Oregon, USA
    Ann Thorac Surg 83:895-901. 2007
    ..We studied the effects of this circuit on cerebral reperfusion because the pathophysiology of "no-reflow" is believed to have an inflammatory component...
  11. doi request reprint Biventricular strategies for neonatal critical aortic stenosis: high mortality associated with early reintervention
    Edward J Hickey
    Congenital Heart Surgeons Society Data Center, Toronto, Ontario, Canada
    J Thorac Cardiovasc Surg 144:409-17, 417.e1. 2012
    ..To characterize the risk of reintervention after biventricular strategies to treat neonatal critical aortic stenosis, and the effect of reintervention on survival...
  12. doi request reprint Congenital supravalvular aortic stenosis: defining surgical and nonsurgical outcomes
    Edward J Hickey
    Division of Cardiovascular Surgery, Department of Surgery, University of Toronto, The Hospital for Sick Children, University of Toronto, Toronto, Canada
    Ann Thorac Surg 86:1919-27; discussion 1927. 2008
    ..Supravalvular aortic stenosis is a rare stenotic lesion of the left ventricular outflow tract (LVOT). We characterized the natural history of the disease and the effect of surgical intervention...
  13. doi request reprint Ross and Yasui operations for complex biventricular repair in infants with critical left ventricular outflow tract obstruction
    Edward J Hickey
    John Kirklin Fellow, The Congenital Heart Surgeons Society Data, Hospital for Sick Children, Toronto, ON, Canada
    Eur J Cardiothorac Surg 37:279-88. 2010
    ..To define the outcomes following Ross and Yasui procedures for complex biventricular repair of critical left ventricular outflow tract obstruction (LVOTO)...
  14. doi request reprint Late risk of outcomes for adults with repaired tetralogy of Fallot from an inception cohort spanning four decades
    Edward J Hickey
    Division of Cardiovascular Surgery, Department of Surgery, University of Toronto, The Hospital for Sick Children, Toronto, Canada
    Eur J Cardiothorac Surg 35:156-64; discussion 164. 2009
    ..We investigated an inception cohort who underwent surgical repair. We aimed to characterize late hazard or risk for death, and determine the time-related risk of late re-operation and pulmonary valve replacement (PVR)...
  15. doi request reprint Is a hybrid strategy a lower-risk alternative to stage 1 Norwood operation?
    Travis J Wilder
    Congenital Heart Surgeons Society Data Center, University of Toronto, The Hospital for Sick Children, Toronto, Ontario, Canada
    J Thorac Cardiovasc Surg . 2016
    ..Despite perceived advantages, however, outcomes are not well defined. Therefore, we compared outcomes after stage 1 hybrid and Norwood procedures...
  16. doi request reprint Jugular venous valved conduit (Contegra) matches allograft performance in infant truncus arteriosus repair
    Edward J Hickey
    The Congenital Heart Surgeons Society Data Center, Toronto, Canada
    Eur J Cardiothorac Surg 33:890-8. 2008
    ..Limited availability and durability of allograft conduits require that alternatives be considered. We compared bovine jugular venous valved (JVV) and allograft conduit performance in 107 infants who survived truncus arteriosus repair...
  17. doi request reprint Long-term tricuspid valve function after Norwood operation
    Maryam Elmi
    Division of Cardiology, Department of Pediatrics, University of Toronto, The Hospital for Sick Children, Toronto, Ontario, Canada
    J Thorac Cardiovasc Surg 142:1341-7.e4. 2011
    ..Long-term functional outcomes after Norwood palliation are likely to depend on tricuspid valve performance in the systemic role. We therefore aimed to characterize features associated with tricuspid valve intervention...
  18. doi request reprint Foetal echocardiographic assessment of borderline small left ventricles can predict the need for postnatal intervention
    Roland W Weber
    The Hospital for Sick Children, Labatt Family Heart Centre, Toronto, Ontario, Canada
    Cardiol Young 23:99-107. 2013
    ..We sought to prospectively determine foetal echocardiographic factors associated with neonatal interventions in borderline hypoplastic left ventricles...
  19. doi request reprint Surgical management of post-repair pulmonary vein stenosis
    Edward J Hickey
    Division of Cardiovascular Surgery and Labatt Family Heart Center, The Hospital for Sick Children, Toronto, Canada
    Semin Thorac Cardiovasc Surg Pediatr Card Surg Annu 14:101-8. 2011
    ..Furthermore, in patients known to be at high risk of recurrent stenosis, sutureless techniques appear to offer improved freedom from recurrent stenosis...
  20. doi request reprint Survival and right ventricular performance for matched children after stage-1 Norwood: Modified Blalock-Taussig shunt versus right-ventricle-to-pulmonary-artery conduit
    Travis J Wilder
    Congenital Heart Surgeons Society Data Center, The Hospital for Sick Children, Toronto, Canada
    J Thorac Cardiovasc Surg 150:1440-50, 1452.e1-8; discussion 1450-2. 2015
    ..We compared trends in survival, RV dysfunction, and tricuspid valve regurgitation (TR) between NW-RVPA and NW-BT for propensity-matched neonates with critical left ventricular outflow tract obstruction (LVOTO)...
  21. doi request reprint Medical errors: the performance gap in hypoplastic left heart syndrome and physiologic equivalents?
    Frederic Jacques
    Labatt Family Heart Centre, The Hospital for Sick Children, University of Toronto, Toronto, Ontario, Canada
    J Thorac Cardiovasc Surg 145:1465-73; discussion 1473-5. 2013
    ..The frequency and impact of medical errors during staged palliation are unknown...
  22. doi request reprint Functional health status of adults with tetralogy of Fallot: matched comparison with healthy siblings
    Rachel Knowles
    Division of Cardiology, Department of Pediatrics, University of Toronto, The Hospital for Sick Children, Toronto, Ontario, Canada
    Ann Thorac Surg 94:124-32. 2012
    ..Attention should therefore shift to assessing and improving functional health status and quality of life. We aimed to assess late functional health status of adults surviving TOF repair by matched comparison to their healthy siblings...
  23. doi request reprint Hypertrophic cardiomyopathy in childhood: disease natural history, impact of obstruction, and its influence on survival
    Edward J Hickey
    Division of Cardiovascular Surgery, Department of Surgery, University of Toronto, The Hospital for Sick Children, Toronto, Ontario, Canada
    Ann Thorac Surg 93:840-8. 2012
    ..We investigated the natural history, outcomes of myectomy, and impact on survival of obstructive hypertrophic cardiomyopathy (HCM) in childhood...
  24. doi request reprint Survival implications: hypertrophic cardiomyopathy in Noonan syndrome
    Edward J Hickey
    Department of Pediatrics, University of Toronto School of Medicine, Toronto, Canada
    Congenit Heart Dis 6:41-7. 2011
    ....
  25. doi request reprint Aggressive Patch Augmentation May Reduce Growth Potential of Hypoplastic Branch Pulmonary Arteries After Tetralogy of Fallot Repair
    Travis J Wilder
    Division of Cardiovascular Surgery, Department of Surgery, University of Toronto, The Hospital for Sick Children, Toronto, Ontario, Canada
    Ann Thorac Surg 101:996-1004. 2016
    ..We explored the effect of these strategies on reintervention and BPA growth...
  26. doi request reprint Infective endocarditis in children: native valve preservation is frequently possible despite advanced clinical disease
    Edward J Hickey
    Department of Surgery, Division of Cardiovascular Surgery, The Hospital for Sick Children, University of Toronto School of Medicine, Toronto, Canada
    Eur J Cardiothorac Surg 35:130-5. 2009
    ..We therefore reviewed all cases of culture-proven IE referred for surgical intervention at our institution over the last three decades...
  27. doi request reprint Aortic valve repair for insufficiency in older children offers unpredictable durability that may not be advantageous over a primary Ross operation†
    Travis J Wilder
    Division of Cardiovascular Surgery, Department of Surgery, The Hospital for Sick Children, The University of Toronto, Toronto, ON, Canada
    Eur J Cardiothorac Surg 49:883-92. 2016
    ..To evaluate the durability of aortic valve (AoV) repair relative to other strategies for children with significant aortic insufficiency (AI)...
  28. doi request reprint Making sense of congenital cardiac disease with a research database: The Congenital Heart Surgeons' Society Data Center
    Edward J Hickey
    The Congenital Heart Surgeons Society Data Center, Toronto, Ontario, Canada
    Cardiol Young 18:152-62. 2008
    ..This report describes the operations of our research database, with particular focus on analytic strategies employed...
  29. ncbi request reprint Lipopolysaccharide preconditioning induces robust protection against brain injury resulting from deep hypothermic circulatory arrest
    Edward J Hickey
    Department of Pediatric Cardiac Surgery, Oregon Health Sciences University, Portland, Ore, USA
    J Thorac Cardiovasc Surg 133:1588-96. 2007
    ..We investigated the potential for lipopolysaccharide to protect against brain injury related to cardiopulmonary bypass...
  30. doi request reprint Systemic arteriovenous fistulae for end-stage cyanosis after cavopulmonary connection: a useful bridge to transplantation
    Edward J Hickey
    Department of Pediatrics, Division of Cardiovascular Surgery, The Hospital for Sick Children, Toronto, Ontario, Canada
    J Thorac Cardiovasc Surg 139:128-134.e1. 2010
    ..Intractable cyanosis after partial or complete cavopulmonary connection may rarely be managed by creating a systemic arteriovenous fistula. We investigated the long-term performance of arteriovenous fistulae...
  31. doi request reprint Surgical management of competing pulmonary blood flow affects survival before Fontan/Kreutzer completion in patients with tricuspid atresia type I
    Travis J Wilder
    Congenital Heart Surgeons Society Data Center, The Hospital for Sick Children, Toronto, Ontario, Canada
    J Thorac Cardiovasc Surg 150:1222-30.e7. 2015
    ..To determine the association between surgical management of pulmonary blood flow (PBF) at initial and staged procedures with survival to Fontan/Kreutzer operation (Fontan) in patients with tricuspid atresia...
  32. ncbi request reprint Critical left ventricular outflow tract obstruction: The disproportionate impact of biventricular repair in borderline cases
    Edward J Hickey
    The Congenital Heart Surgeon s Society Data Center, Toronto, Ontario, Canada
    J Thorac Cardiovasc Surg 134:1429-36; discussion 1436-7. 2007
    ..We hypothesized that pursuit of biventricular repair in borderline candidates increases mortality...
  33. doi request reprint Unexpected contained rupture of a ductus arteriosus aneurysm found at surgical repair in an infant with Loeys-Dietz syndrome
    Frederic Jacques
    Department of Surgery and Pediatrics, Division of Cardiovascular Surgery, Labatt Family Heart Centre, Toronto, Ontario, Canada
    Ann Thorac Surg 95:710-1. 2013
    ..We report the successful surgical management in a 1-month-old infant with Loeys-Dietz syndrome of a ductus arteriosus aneurysm with an unexpected contained rupture found at the time of surgery...
  34. ncbi request reprint Effects of circuit miniaturization in reducing inflammatory response to infant cardiopulmonary bypass by elimination of allogeneic blood products
    Edward Hickey
    Division of Pediatric Cardiac Surgery, Oregon Health Sciences University, Portland, Oregon 97201 3098, USA
    Ann Thorac Surg 81:S2367-72. 2006
    ..In this article, we review the data supporting this rationale and provide the results from studies in our laboratory that emphasize the benefits of circuit miniaturization...
  35. doi request reprint Long-Term Outcomes of the Ross Procedure Versus Mechanical Aortic Valve Replacement: Propensity-Matched Cohort Study
    Amine Mazine
    From Division of Cardiovascular Surgery, Peter Munk Cardiac Centre, Toronto General Hospital and University of Toronto, Toronto, ON, Canada
    Circulation 134:576-85. 2016
    ..The ideal aortic valve substitute in young and middle-aged adults remains unknown. We sought to compare the long-term outcomes of patients undergoing the Ross procedure and those receiving a mechanical aortic valve replacement (AVR)...
  36. pmc The contribution of left ventricular muscle bands to left ventricular rotation: assessment by a 2-dimensional speckle tracking method
    Ling Hui
    Pediatric Cardiology, Oregon Health Science University, Portland, Oregon 97239 3098, USA
    J Am Soc Echocardiogr 20:486-91. 2007
    ..Our aim was to identify the relative contributions of the inner or outer layers of the LV wall to rotation and, hence, systole...
  37. doi request reprint Outcomes of emergent cardiac catheterization following pediatric cardiac surgery
    Kentaro Asoh
    Division of Cardiology, Department of Pediatrics, The Labatt Family Cardiac Center, The Hospital for Sick Children, University of Toronto School of Medicine, Toronto, Canada
    Catheter Cardiovasc Interv 73:933-40. 2009
    ..The focus of this study was to explore the indications for and determinants of outcome after cardiac catheterization in this setting...
  38. ncbi request reprint Live real-time three-dimensional echocardiography for the visualization of myocardial perfusion--a pilot study in open-chest pigs
    James Pemberton
    Clinical Care Center for Congenital Heart Disease, Oregon Health and Science University, Portland, Oregon 97239 3098, USA
    J Am Soc Echocardiogr 18:956-8. 2005
    ..We present the findings of our experimental pilot study of myocardial perfusion detection using live real-time 3-dimensional echocardiography in an animal model...
  39. ncbi request reprint Complete vascular ring presenting in adulthood: an unusual management dilemma
    Edward J Hickey
    Department of Thoracic Surgery, Guy s Hospital, King s College London, London, United Kingdom
    J Thorac Cardiovasc Surg 134:235-6. 2007