Denis Daneman

Summary

Affiliation: The Hospital for Sick Children
Country: Canada

Publications

  1. ncbi request reprint Type 1 diabetes
    Denis Daneman
    Division of Endocrinology, Department of Paediatrics, Hospital for Sick Children and University of Toronto, Toronto, ON, Canada M5G 1X8
    Lancet 367:847-58. 2006
  2. doi request reprint State of the world's children with diabetes
    Denis Daneman
    Department of Pediatrics, University of Toronto, The Hospital for Sick Children, Toronto, Canada
    Pediatr Diabetes 10:120-6. 2009
  3. ncbi request reprint Early diabetes-related complications in adolescents: risk factors and screening
    Denis Daneman
    Division of Endocrinology, The Hospital for Sick Children and University of Toronto, 555 University Avenue, Toronto, Ontario M5P 1X8, Canada
    Horm Res 63:75-85. 2005
  4. ncbi request reprint Diagnostic imaging of the thyroid and adrenal glands in childhood
    Denis Daneman
    Department of Pediatrics, Hospital for Sick Children, Toronto, ON, Canada
    Endocrinol Metab Clin North Am 34:745-68, xi. 2005
  5. ncbi request reprint Type 1 diabetes and autism: is there a link?
    Sloane J Freeman
    Division of Endocrinology, The Hospital for Sick Children, Toronto, Ontario, Canada
    Diabetes Care 28:925-6. 2005
  6. doi request reprint Insulin sensitivity and secretion in children and adolescents with hypothalamic obesity following treatment for craniopharyngioma
    Judith Simoneau-Roy
    Division of Endocrinology, The Hospital for Sick Children, and University of Toronto, Toronto, ON, Canada
    Clin Endocrinol (Oxf) 72:364-70. 2010
  7. pmc Prediction of the onset of disturbed eating behavior in adolescent girls with type 1 diabetes
    Marion P Olmsted
    Behavioural Sciences and Health Research Division, Toronto General Research Institute, University Health Network, Toronto, Ontario, Canada
    Diabetes Care 31:1978-82. 2008
  8. doi request reprint Transition to adult care for youths with diabetes mellitus: findings from a Universal Health Care System
    Meranda Nakhla
    Division of Endocrinology and Metabolism, Hospital for Sick Children, Toronto, Ontario, Canada
    Pediatrics 124:e1134-41. 2009
  9. doi request reprint Dermatological complications of continuous subcutaneous insulin infusion in children and adolescents
    Louise S Conwell
    Division of Endocrinology, Department of Pediatrics, The Hospital for Sick Children, University of Toronto, Toronto, Ontario, Canada
    J Pediatr 152:622-8. 2008
  10. ncbi request reprint Exercise and type 1 diabetes mellitus in youth; review and recommendations
    Mariana Rachmiel
    Division of Endocrinology, Hospital for Sick Children, Toronto, Canada
    Pediatr Endocrinol Rev 5:656-65. 2007

Detail Information

Publications77

  1. ncbi request reprint Type 1 diabetes
    Denis Daneman
    Division of Endocrinology, Department of Paediatrics, Hospital for Sick Children and University of Toronto, Toronto, ON, Canada M5G 1X8
    Lancet 367:847-58. 2006
    ..Nonetheless, major challenges remain in the development of approaches to the prevention and management of type 1 diabetes and its complications...
  2. doi request reprint State of the world's children with diabetes
    Denis Daneman
    Department of Pediatrics, University of Toronto, The Hospital for Sick Children, Toronto, Canada
    Pediatr Diabetes 10:120-6. 2009
    ..Only when every single child with diabetes has ready access to experienced health care professionals, insulin, and other supplies, food water and protection will the first part of the job be done...
  3. ncbi request reprint Early diabetes-related complications in adolescents: risk factors and screening
    Denis Daneman
    Division of Endocrinology, The Hospital for Sick Children and University of Toronto, 555 University Avenue, Toronto, Ontario M5P 1X8, Canada
    Horm Res 63:75-85. 2005
    ..This article reviews the literature that underpins the available guidelines and stresses the pivotal role of excellent metabolic control in complication prevention...
  4. ncbi request reprint Diagnostic imaging of the thyroid and adrenal glands in childhood
    Denis Daneman
    Department of Pediatrics, Hospital for Sick Children, Toronto, ON, Canada
    Endocrinol Metab Clin North Am 34:745-68, xi. 2005
    ....
  5. ncbi request reprint Type 1 diabetes and autism: is there a link?
    Sloane J Freeman
    Division of Endocrinology, The Hospital for Sick Children, Toronto, Ontario, Canada
    Diabetes Care 28:925-6. 2005
  6. doi request reprint Insulin sensitivity and secretion in children and adolescents with hypothalamic obesity following treatment for craniopharyngioma
    Judith Simoneau-Roy
    Division of Endocrinology, The Hospital for Sick Children, and University of Toronto, Toronto, ON, Canada
    Clin Endocrinol (Oxf) 72:364-70. 2010
    ..It has been suggested that abnormalities of insulin secretion and/or insulin action due to hypothalamic injury may be associated with weight gain and the metabolic syndrome in this population...
  7. pmc Prediction of the onset of disturbed eating behavior in adolescent girls with type 1 diabetes
    Marion P Olmsted
    Behavioural Sciences and Health Research Division, Toronto General Research Institute, University Health Network, Toronto, Ontario, Canada
    Diabetes Care 31:1978-82. 2008
    ..The purpose of this study was to identify predictors of the onset of disturbed eating behavior (DEB) in adolescent girls with type 1 diabetes...
  8. doi request reprint Transition to adult care for youths with diabetes mellitus: findings from a Universal Health Care System
    Meranda Nakhla
    Division of Endocrinology and Metabolism, Hospital for Sick Children, Toronto, Ontario, Canada
    Pediatrics 124:e1134-41. 2009
    ....
  9. doi request reprint Dermatological complications of continuous subcutaneous insulin infusion in children and adolescents
    Louise S Conwell
    Division of Endocrinology, Department of Pediatrics, The Hospital for Sick Children, University of Toronto, Toronto, Ontario, Canada
    J Pediatr 152:622-8. 2008
    ..To assess their association with duration of CSII, age, adiposity, HbA1(c), insulin dose, insulin brand, infusion set or site...
  10. ncbi request reprint Exercise and type 1 diabetes mellitus in youth; review and recommendations
    Mariana Rachmiel
    Division of Endocrinology, Hospital for Sick Children, Toronto, Canada
    Pediatr Endocrinol Rev 5:656-65. 2007
    ..We discuss its physiological and metabolic effects in youth with T1DM, its health promoting benefits and challenges that exercise poses in these individuals...
  11. doi request reprint Type 2 diabetes in children and adolescents
    Shazhan Amed
    The Hospital for Sick Children and University of Toronto, 555 University Avenue, Toronto, Ontario, Canada
    Expert Rev Cardiovasc Ther 8:393-406. 2010
    ..Here, we highlight the epidemiology, pathophysiology, risk factors, clinical presentation and diagnosis, treatment and public health impact of T2D in children and adolescents...
  12. doi request reprint Association Between Plasma Uric Acid Levels and Cardiorenal Function in Adolescents With Type 1 Diabetes
    Yuliya Lytvyn
    Department of Pharmacology and Toxicology, University of Toronto, Toronto, Canada Division of Nephrology, Department of Medicine, The University Health Network, University of Toronto, Toronto, Canada
    Diabetes Care 39:611-6. 2016
    ..These associations were also studied in healthy control (HC) subjects...
  13. doi request reprint The urinary inflammatory profile in gluten free diet-adherent adolescents with type 1 diabetes and celiac disease
    Emilia N De Melo
    Department of Pediatrics, Division of Endocrinology, Hospital for Sick Children, University of Toronto, 555 University Avenue, Toronto, ON, Canada
    J Diabetes Complications 30:295-9. 2016
    ....
  14. doi request reprint Quality of life in children with diabetes and celiac disease: minimal impact of the 'double diagnosis'
    Shama Sud
    Division of Endocrinology, Department of Pediatrics, Hospital for Sick Children, University of Toronto, Toronto, ON, Canada
    Pediatr Diabetes 13:163-9. 2012
    ..Many diabetes clinics are apprehensive about the prospect of introducing a second illness requiring intensive lifestyle changes in patients and families already managing a chronic condition, especially in asymptomatic patients...
  15. ncbi request reprint Five-year prevalence and persistence of disturbed eating behavior and eating disorders in girls with type 1 diabetes
    Patricia A Colton
    University Health Network, Toronto, Ontario, Canada
    Diabetes Care 30:2861-2. 2007
  16. ncbi request reprint Eating disorders in young women with type 1 diabetes mellitus
    Gary Rodin
    Department of Psychiatry, Toronto General Hospital, University Health Network, Toronto, Ontario, Canada
    J Psychosom Res 53:943-9. 2002
    ..The evaluation of these and other treatment approaches is indicated in view of the serious short- and long-term health risks associated with eating disorders in young women with diabetes...
  17. doi request reprint Validation of a health administrative data algorithm for assessing the epidemiology of diabetes in Canadian children
    Astrid Guttmann
    Institute for Clinical Evaluative Sciences, Toronto, Ontario, Canada
    Pediatr Diabetes 11:122-8. 2010
    ..To validate a case definition of pediatric diabetes using administrative health data and describe trends in incidence and prevalence over time in Ontario, Canada...
  18. doi request reprint Social Determinants of Health Are Associated with Modifiable Risk Factors for Cardiovascular Disease and Vascular Function in Pediatric Type 1 Diabetes
    Mark Inman
    Department of Pediatrics, The Hospital for Sick Children and University of Toronto, Toronto, Ontario, Canada
    J Pediatr 177:167-72. 2016
    ..To evaluate the relationship between social determinants of health (SDH) and cardiovascular disease (CVD) risk factors as well as a measure of arterial stiffness in adolescents with type 1 diabetes (T1D)...
  19. doi request reprint Depression, disturbed eating behavior, and metabolic control in teenage girls with type 1 diabetes
    Patricia A Colton
    Department of Psychiatry, University Health Network, Toronto, ON, Canada
    Pediatr Diabetes 14:372-6. 2013
    ..Depression and disturbed eating behavior (DEB) are more common in girls with type 1 diabetes (T1D) than in the general population, and may negatively affect metabolic control...
  20. ncbi request reprint Metformin as an adjunct therapy in adolescents with type 1 diabetes and insulin resistance: a randomized controlled trial
    Jill Hamilton
    Division of Endocrinology, Hospital for Sick Children, Toronto, Ontario, Canada
    Diabetes Care 26:138-43. 2003
    ....
  21. ncbi request reprint Continuous glucose monitoring in adolescents with cystic fibrosis
    Craig Jefferies
    Division of Endocrinology, Hospital for Sick Children, University of Toronto Toronto, Ontario, Canada
    J Pediatr 147:396-8. 2005
    ..CGMS confirmed diabetic glucose excursions in 7/19 subjects deemed diabetic on oral glucose tolerance testing. CGMS is a useful tool for detecting hyperglycemia in CF...
  22. ncbi request reprint Pioglitazone as adjunctive therapy in adolescents with type 1 diabetes
    Vera Zdravkovic
    Division of Endocrinology, Hospital for Sick Children, Toronto, Ontario, Canada
    J Pediatr 149:845-849. 2006
    ..To determine whether the addition of the thiazoladinedione, pioglitazone, to standard therapy improves metabolic control in adolescents with type 1 diabetes (T1D) and clinical evidence of insulin resistance...
  23. pmc Low socioeconomic status is associated with adverse events in children and teens on insulin pumps under a universal access program: a population-based cohort study
    Rayzel Shulman
    Department of Pediatrics, Hospital for Sick Children, University of Toronto, Toronto, Ontario, Canada Sickkids Research Institute Institute of Health Policy, Management and Evaluation, University of Toronto, Toronto, Ontario, Canada Institute for Clinical Evaluative Sciences, Toronto, Ontario, Canada
    BMJ Open Diabetes Res Care 4:e000239. 2016
    ..To describe adverse events in pediatric insulin pump users since universal funding in Ontario and to explore the role of socioeconomic status and 24-hour support...
  24. ncbi request reprint Insulin analogues in children and teens with type 1 diabetes: advantages and caveats
    Marianna Rachmiel
    Division of Endocrinology, Department of Pediatrics, The Hospital for Sick Children and University of Toronto, 555 University Avenue, Toronto, Ontario, Canada M5G 1X8
    Pediatr Clin North Am 52:1651-75. 2005
    ..We also address briefly the use of adjunctive agents in the treatment of type 1 diabetes in children and teens...
  25. ncbi request reprint Continuous subcutaneous insulin infusion pump treatment in children with type 1 diabetes mellitus
    Raphael Liberatore
    Division of Endocrinology, Department of Pediatrics, The Hospital for Sick Children and University of Toronto, Canada
    J Pediatr Endocrinol Metab 17:223-6. 2004
    ..45 kg/m2) and total daily dose of insulin (-0.23 U/kg/day) were found between the start of pump use and evaluation 6-30 months later. There was a close correlation between the HbA1c before and after 6-30 months of pump therapy...
  26. ncbi request reprint Potential adjunctive therapies in adolescents with type 1 diabetes mellitus
    Craig A Jefferies
    Division of Endocrinology, Department of Pediatrics, The Hospital for Sick Children, University of Toronto, Toronto, Ontario M5G 1X8, Canada
    Treat Endocrinol 3:337-43. 2004
    ....
  27. pmc Resources and population served: a description of the Ontario Paediatric Diabetes Network
    Rayzel Shulman
    Department of Pediatrics Shulman, Daneman, Guttmann, The Hospital for Sick Children, University of Toronto Institute of Health Policy, Management and Evaluation Shulman, Miller, Stukel, Guttmann, University of Toronto Institute for Clinical Evaluative Sciences Shulman, Stukel, Guttmann Toronto Health Economics and Technology Assessment THETA Collaborative Miller, University of Toronto, Toronto, Ont
    CMAJ Open 4:E141-6. 2016
    ..The objective of this study was to describe the distribution of patients, resources and insulin pump use across centres within the network, now called the Ontario Paediatric Diabetes Network...
  28. doi request reprint The effect of aliskiren on urinary cytokine/chemokine responses to clamped hyperglycaemia in type 1 diabetes
    David Z I Cherney
    Division of Nephrology, University Health Network Toronto General Hospital, Banting and Best Diabetes Centre, University of Toronto, 585 University Ave, 8N 845, Toronto, ON M5G 2N2, Canada
    Diabetologia 56:2308-17. 2013
    ....
  29. ncbi request reprint Nutrition education program design for youth with type 2 diabetes mellitus
    Jennifer Buccino
    Division of Endocrinology, The Hospital for Sick Children, Toronto, Ontario, Canada
    Can J Diet Pract Res 69:192-7. 2008
    ..Together with program development strategies, a summary of relevant content and mode of delivery is presented for a nutrition education program intended specifically for youth with T2DM at The Hospital for Sick Children...
  30. doi request reprint Dead-in-bed syndrome - a diabetes nightmare
    Dror Koltin
    Division of Endocrinology, Department of Paediatrics, The Hospital for Sick Children, University of Toronto, Toronto, Ontario, Canada
    Pediatr Diabetes 9:504-7. 2008
    ....
  31. doi request reprint Incidental thyroid abnormalities identified on neck US for non-thyroid disorders
    Shivaram Avula
    Department of Diagnostic Imaging, The Hospital for Sick Children and University of Toronto, 555 University Ave, Toronto, ON M5G 1X8, Canada
    Pediatr Radiol 40:1774-80. 2010
    ..Incidental thyroid abnormalities detected on US examinations in children have not been well documented...
  32. doi request reprint Prevention of type 1 diabetes
    DIANE K WHERRETT
    Division of Endocrinology, Department of Pediatrics, The Hospital for Sick Children and University of Toronto, 555 University Avenue, Toronto, Ontario M5G 1X8, Canada
    Pediatr Clin North Am 58:1257-70, xi. 2011
    ..Knowledge in this area has grown quickly in recent years and will continue to grow rapidly with several international collaborative efforts underway...
  33. ncbi request reprint Final height in children with idiopathic growth hormone deficiency treated with a fixed dose of recombinant growth hormone
    Marianna Rachmiel
    Division of Endocrinology, Department of Pediatrics, The Hospital for Sick Children, University of Toronto, Toronto, Ontario, Canada
    Horm Res 68:236-43. 2007
    ..51; p < 0.005). Treatment of children with idiopathic GHD with a fixed dose of 0.18 mg/kg/week rhGH is sufficient to reach FAH within 2 SDS of the normal population range (84%) with an average FAH within -0.5 SDS of midparental height...
  34. doi request reprint Is diabetic ketoacidosis at disease onset a result of missed diagnosis?
    Helen Bui
    Division of Endocrinology, Department of Pediatrics, The Hospital for Sick Children and University of Toronto, Toronto, Ontario, Canada
    J Pediatr 156:472-7. 2010
    ..To determine the frequency of medical encounters before diagnosis of diabetes in children in Ontario, Canada; to determine risk factors for diabetic ketoacidosis (DKA)...
  35. ncbi request reprint Self-monitoring of blood glucose in children and teens with diabetes
    Helen Bui
    Division of Endocrinology, Department of Pediatrics, The Hospital for Sick Children and University of Toronto, Toronto, Ontario, Canada
    Pediatr Diabetes 6:50-62. 2005
    ..However, inconsistency in their accuracy and precision remain challenges when using these technologies to guide management...
  36. ncbi request reprint Color visual evoked potentials in children with type 1 diabetes: relationship to metabolic control
    Yesmino T Elia
    Department of Ophthalmology and Vision Sciences, The Hospital for Sick Children and University of Toronto, Canada
    Invest Ophthalmol Vis Sci 46:4107-13. 2005
    ..To examine the association between metabolic control (HbA(1c)) and the chromatic mechanisms of children with type 1 diabetes (T1D), by using the color visual evoked potential (VEP)...
  37. ncbi request reprint Predictors of glucose control in children and adolescents with type 1 diabetes mellitus
    Stacey L Urbach
    Department of Public Health and Preventive Medicine, Oregon Health and Science University, Portland, OR, USA
    Pediatr Diabetes 6:69-74. 2005
    ..To evaluate the glucose control [(as measured by hemoglobin A1c (HbA1c)], the factors associated with glycemic control, and possible explanations for these associations in a sample of children and adolescents with type 1 diabetes...
  38. ncbi request reprint Congenital hypothyroidism: a review of current diagnostic and treatment practices in relation to neuropsychologic outcome
    Joanne Rovet
    Department of Pediatrics, University of Toronto, Toronto, Ontario, Canada
    Paediatr Drugs 5:141-9. 2003
    ....
  39. ncbi request reprint Dissemination to research subjects: operationalizing investigator accountability
    Randi Zlotnik Shaul
    Bioethics Department, The Hospital for Sick Children, 555 University Ave, Toronto, Ontario M5G 1X8 Canada
    Account Res 12:1-16. 2005
    ....
  40. doi request reprint Insulin pump use and discontinuation in children and teens: a population-based cohort study in Ontario, Canada
    Rayzel Shulman
    Department of Pediatrics, Hospital for Sick Children, University of Toronto, Toronto, Canada
    Pediatr Diabetes . 2016
    ....
  41. doi request reprint Eating Disorders in Girls and Women With Type 1 Diabetes: A Longitudinal Study of Prevalence, Onset, Remission, and Recurrence
    Patricia A Colton
    Department of Psychiatry, University Health Network, Toronto, Canada Department of Psychiatry, University of Toronto, Toronto, Canada
    Diabetes Care 38:1212-7. 2015
    ..This study describes the longitudinal course of disturbed eating behavior (DEB) and EDs in a cohort with type 1 diabetes...
  42. doi request reprint Assessing social determinants of health in a pediatric diabetes clinical research trial: Are recruited subjects representative of the larger clinical population?
    Mark Inman
    Department of Pediatrics, Hospital for Sick Children, University of Toronto, Toronto, ON, Canada
    Diabetes Res Clin Pract 113:41-3. 2016
    ..Using a validated tool, SDH dimensions were compared between adolescents enrolled and not enrolled into a large diabetes study. We observed that our study cohort reflected a SDH profile mirroring the eligible population. ..
  43. pmc The urinary cytokine/chemokine signature of renal hyperfiltration in adolescents with type 1 diabetes
    Ron L H Har
    Division of Nephrology, University Health Network Toronto General Hospital, Banting and Best Diabetes Centre, University of Toronto, Toronto, Ontario, Canada
    PLoS ONE 9:e111131. 2014
    ..Our second aim was to determine the relationship between urine and plasma levels of inflammatory biomarkers, to clarify the origin of these factors...
  44. ncbi request reprint Metabolic control in adolescent girls: links to relationality and the female sense of self
    Sherry Maharaj
    Department of Psychiatry, Toronto General Hospital, University Health Network, Toronto, Ontario, Canada
    Diabetes Care 27:709-15. 2004
    ..This study investigated whether intimacy and autonomy in mother-daughter interactions and relational aspects of the self are associated with metabolic control in adolescent girls with type 1 diabetes...
  45. ncbi request reprint Early onset of severe diabetes mellitus-related microvascular complications
    Jill Hamilton
    Departments of Pediatrics and Medicine, the Hospital for Sick Children and University Health Network, University of Toronto, Toronto, Ontario, Canada
    J Pediatr 144:281-3. 2004
    ..We speculate on potential mechanisms that may have contributed to the rapid development of diabetes mellitus-related complications...
  46. doi request reprint Sleep-disordered breathing is increased in obese adolescents with craniopharyngioma compared with obese controls
    Clodagh S O'Gorman
    Hospital for Sick Children, 555 University Avenue, Toronto, Ontario, Canada
    J Clin Endocrinol Metab 95:2211-8. 2010
    ..Retrospective studies suggest that adolescents with craniopharyngioma and hypothalamic obesity have increased sleep-disordered breathing (SDB)...
  47. doi request reprint Thyroid cancer in childhood: a retrospective review of childhood course
    Clodagh S O'Gorman
    The Hospital for Sick Children, Toronto, Canada
    Thyroid 20:375-80. 2010
    ..The objectives of this study were to describe the demographics and outcomes in children with TC treated at The Hospital for Sick Children, Toronto, from 1983 to 2006. We hypothesized that childhood TC was increasing at our institution...
  48. ncbi request reprint Cardiac failure after initiation of insulin treatment in diabetic patients with beta-thalassemia major
    Daniel Konrad
    Division of Endocrinology, Hospital for Sick Children, University of Toronto, 555 University Avenue, Toronto, Ontario M5G 1X8, Canada
    J Pediatr 143:541-2. 2003
    ..We hypothesize that insulin-induced fluid retention combined with reduced cardiac reserve was responsible for the cardiac failure. Careful initiation of insulin treatment in these patients is important...
  49. ncbi request reprint Cardiac and vascular function in adolescents and young adults with type 1 diabetes
    Elizabeth Berger
    Division of Endocrinology, Department of Pediatrics, The Hospital for Sick Children and University of Toronto, Toronto, Ontario, Canada
    Diabetes Technol Ther 6:129-35. 2004
    ..The reason for the improvement is uncertain, but may relate to the improvement of insulin sensitivity at the end of the pubertal growth period, rather than to changes in metabolic control or lipid profiles...
  50. ncbi request reprint Necrotizing fasciitis in adolescents with poorly controlled type 1 diabetes mellitus: report of two cases
    Louise S Conwell
    Division of Endocrinology, Department of Paediatrics, Hospital for Sick Children, University of Toronto, Toronto, Canada M5G 1X8
    Pediatr Diabetes 8:397-400. 2007
    ..The associations between diabetes and the incidence or outcome of NF in children and adolescents are not known. In all cases, early identification and aggressive surgical intervention are important for limiting morbidity and mortality...
  51. pmc Hypothalamic Obesity following Craniopharyngioma Surgery: Results of a Pilot Trial of Combined Diazoxide and Metformin Therapy
    Jill K Hamilton
    Division of Endocrinology, Department of Pediatrics, The Hospital for Sick Children, University of Toronto, Toronto, ON, Canada M5G 1X8
    Int J Pediatr Endocrinol 2011:417949. 2011
    ..96, P = .009). Conclusion. Combined diazoxide-metformin therapy was associated with reduced weight gain in patients with hypothalamic obesity. AUC(ins) at study commencement predicted effectiveness of the treatment...
  52. ncbi request reprint Exercise interventions in obese youth: are they effective?
    Melanie Henderson
    Department of HPME, University of Toronto, Toronto, ON, Canada
    J Pediatr Endocrinol Metab 21:823-6. 2008
    ..Physical activity counseling interventions have emerged as an effective and inexpensive alternative to traditional, structured exercise programs in adults, and may be an interesting option for the treatment of obesity in youth...
  53. doi request reprint Valuing technology: A qualitative interview study with physicians about insulin pump therapy for children with type 1 diabetes
    Rayzel Shulman
    Department of Pediatrics, Hospital for Sick Children, University of Toronto, Toronto, Ontario, Canada Institute of Health Policy, Management and Evaluation, University of Toronto, Toronto, Ontario, Canada Institute for Clinical Evaluative Sciences, Toronto, Ontario, Canada
    Health Policy 120:64-71. 2016
    ..Understanding how technologies are valued can help stakeholders decide how to address such beliefs and expectations in funding decisions and implementation protocols...
  54. ncbi request reprint McCune-Albright syndrome
    Alan Daneman
    Departments of Diagnostic Imaging, The Hospital for Sick Children, University of Toronto
    J Pediatr Endocrinol Metab 20:1265. 2007
  55. ncbi request reprint The effects of psychoeducation on disturbed eating attitudes and behavior in young women with type 1 diabetes mellitus
    Marion P Olmsted
    Ambulatory Care for Eating Disorders, Toronto General Hospital, University Health Network, Toronto, Ontario, Canada
    Int J Eat Disord 32:230-9. 2002
    ..This study aimed to evaluate the effect of a six-session psychoeducation (PE) program on young women with type 1 diabetes mellitus (DM) and disordered eating attitudes and behavior...
  56. pmc Celiac disease and pediatric type 1 diabetes: diagnostic and treatment dilemmas
    Shama Sud
    Division of Endocrinology, Department of Pediatrics, The Hospital for Sick Children, University of Toronto, Toronto, ON, Canada M5G 1X8
    Int J Pediatr Endocrinol 2010:161285. 2010
    ..This review focuses on current knowledge of CD in children and youth with T1D, highlighting important elements of the disease's pathophysiology, epidemiology, clinical presentation, and diagnostic challenges...
  57. ncbi request reprint Recent trends in hospitalization for diabetic ketoacidosis in ontario children
    Jacqueline R Curtis
    Department of Pediatrics, Division of Endocrinology, The Hospital for Sick Children, University of Toronto, Toronto, Ontario, Canada
    Diabetes Care 25:1591-6. 2002
    ..To investigate trends and geographic variation in diabetic ketoacidosis (DKA) hospitalization rates among children in Ontario from 1991 to 1999...
  58. ncbi request reprint Islet cell transplantation and other new technologies for treating type 1 diabetes: a paediatric view
    Denis Daneman
    Division of Endocrinology, Department of Pediatrics, The Hospital for Sick Children and University of Toronto, Ontario, Canada
    Horm Res 57:54-9. 2002
    ..However, serious questions regarding long-term safety and efficacy need to be answered in older individuals before consideration is given to their more routine use in children and adolescents with diabetes...
  59. ncbi request reprint Translating transition: a critical review of the diabetes literature
    Meranda Nakhla
    Division of Endocrinologye, Department ofPaediatrics, University of Toronto, Ontario, Canada
    J Pediatr Endocrinol Metab 21:507-16. 2008
    ....
  60. ncbi request reprint Growth hormone deficiency in Costello syndrome
    Robert I Stein
    Department of Paediatrics, Division of Endocrinology, Children s Hospital of Western Ontario, University of Western Ontario, London, Canada
    Am J Med Genet A 129:166-70. 2004
    ..We review the pathophysiology of Costello syndrome and highlight the recent recommendations of tumor screening and cardiac surveillance in this population, of particular relevance to those receiving GH therapy...
  61. pmc Prevention of type 1 diabetes
    DIANE K WHERRETT
    Department of Pediatrics, The Hospital for Sick Children and University of Toronto, Ontario, Canada
    Endocrinol Metab Clin North Am 38:777-90. 2009
    ..Knowledge in this area has grown quickly in recent years and will continue to grow rapidly with several international collaborative efforts underway...
  62. ncbi request reprint Is carotid ultrasound a useful tool in assessing cardiovascular disease in individuals with diabetes?
    Amish Parikh
    Division of Endocrinology, Department of Pediatrics, University of Toronto and The Hospital for Sick Children, Toronto, Ontario, Canada
    Diabetes Technol Ther 6:65-9. 2004
    ..However, IMT measurements in the children and teens with Type 1 diabetes have yielded conflicting results, and larger, longitudinal studies are needed in this area...
  63. ncbi request reprint Deteriorating diabetes control during adolescence: physiological or psychosocial?
    Jill Hamilton
    Department of Pediatrics, The Hospital for Sick Children, University of Toronto, Canada
    J Pediatr Endocrinol Metab 15:115-26. 2002
    ..In this review, we examine the impact of physiological and psychosocial changes during puberty in type 1 DM, highlight treatment strategies aimed at modifying these factors, and suggest further interventions that warrant evaluation...
  64. ncbi request reprint Population-based study of incidence and risk factors for cerebral edema in pediatric diabetic ketoacidosis
    Sarah E Lawrence
    Department of Pediatrics, Children s Hospital of Eastern Ontario, 401 Smyth Road, Ottawa, Ontario, Canada K1H 8L1
    J Pediatr 146:688-92. 2005
    ..To determine incidence, outcomes, and risk factors for pediatric cerebral edema with diabetic ketoacidosis (CEDKA) in Canada...
  65. ncbi request reprint Pascal's Wager: from science to policy on early childhood development
    Avram E Denburg
    Department of Paediatrics, The Hospital for Sick Children Toronto, ON
    Can J Public Health 101:235-6. 2010
    ..Properly implemented, it could serve as a model for such policy across the country. Its successful adoption will require sustained advocacy and ongoing research by the Canadian medical community...
  66. ncbi request reprint Growth and sexual maturation during long-term treatment with risperidone
    Fiona Dunbar
    Janssen Ortho Inc, Toronto, Ontario, M3C 1L9 Canada
    Am J Psychiatry 161:918-20. 2004
    ..This study assessed the impact of risperidone on growth and sexual maturation...
  67. ncbi request reprint Insulin injection regimens and metabolic control in an international survey of adolescents with type 1 diabetes over 3 years: results from the Hvidore study group
    Reinhard W Holl
    University of Ulm, ZIBMT, Albert Einstein Allee 47, 89081 Ulm, Germany
    Eur J Pediatr 162:22-9. 2003
    ..7+/-1.6%; 1998 observed: 8.9+/-1.6%, HbA(1c) expected for 1998: 9.0%). BMI increased more than expected, the increase was greatest in patients switching from twice daily to multiple injections, and higher in females compared to males...
  68. ncbi request reprint Disturbed eating behavior and eating disorders in preteen and early teenage girls with type 1 diabetes: a case-controlled study
    Patricia Colton
    Department of Psychiatry, University of Toronto, Ontario Canada p colton utoronto ca
    Diabetes Care 27:1654-9. 2004
    ..To compare the prevalence of eating disturbances in preteen and early teenage girls with type 1 diabetes to their nondiabetic peers...
  69. ncbi request reprint [Eating disturbances in adolescent girls with type 1 diabetes mellitus]
    Rinat Nissim
    Department of Psychiatry, General Hospital of Toronto, Ontario District, Canada
    Harefuah 141:902-7, 929. 2002
    ..Clinic-based psychoeducational programs may be effective for prevention or early intervention. Severe eating disorders require more intensive intervention, tailored to address the DM context...
  70. ncbi request reprint Diabetic ketoacidosis
    Joseph Wolfsdorf
    Division of Endocrinology, Children s Hospital Boston, Boston, MA, USA
    Pediatr Diabetes 8:28-43. 2007
  71. ncbi request reprint Clonidine ingestion in children is not uneventful
    Marianna Rachmiel
    J Pediatr 148:850; author reply 850-1. 2006
  72. ncbi request reprint European Society for Paediatric Endocrinology/Lawson Wilkins Pediatric Endocrine Society consensus statement on diabetic ketoacidosis in children and adolescents
    David B Dunger
    European Society for Paediatric Endocrinology, West Smithfield, London, United Kingdom
    Pediatrics 113:e133-40. 2004
  73. ncbi request reprint Prolactin levels during long-term risperidone treatment in children and adolescents
    Robert L Findling
    University Hospitals of Cleveland Case Western Reserve University, Cleveland, Ohio 44106, USA
    J Clin Psychiatry 64:1362-9. 2003
    ..This analysis was designed to investigate prolactin levels in children and adolescents on long-term risperidone treatment and explore any relationship with side effects hypothetically attributable to prolactin (SHAP)...
  74. ncbi request reprint Routine psychological screening in youth with type 1 diabetes and their parents: a notion whose time has come?
    Fergus J Cameron
    Department of Endocrinology and Diabetes, Royal Children s Hospital, Parkville, Melbourne, Victoria 3052, Australia
    Diabetes Care 30:2716-24. 2007
  75. ncbi request reprint The global burden of youth diabetes: perspectives and potential
    Henk Jan Aanstoot
    DIABETER, Centre for Pediatric and Adolescent Diabetes Care and Research, Rotterdam, The Netherlands
    Pediatr Diabetes 8:1-44. 2007
  76. pmc Pediatric diabetic ketoacidosis
    Sarah Lawrence
    CMAJ 169:278-9; author reply 279. 2003