Sarah Alexander

Summary

Affiliation: The Hospital for Sick Children
Country: Canada

Publications

  1. pmc Prevention of bacterial infection in pediatric oncology: what do we know, what can we learn?
    Sarah Alexander
    Division of Hematology Oncology, Hospital for Sick Children, Toronto, Ontario, Canada
    Pediatr Blood Cancer 59:16-20. 2012
  2. doi Rituximab and desensitization for a patient with severe factor IX deficiency, inhibitors, and history of anaphylaxis
    Sarah Alexander
    Division of Paediatric Haematology, University of Toronto, Toronto, Ontario, Canada
    J Pediatr Hematol Oncol 30:93-5. 2008
  3. doi Evaluation of treatment-related mortality among paediatric cancer deaths: a population based analysis
    Jason D Pole
    Pediatric Oncology Group of Ontario, 480 University Ave, Toronto, Ontario, M5G 1V2, Canada
    Br J Cancer . 2017
  4. doi Parent and clinician preferences for location of end-of-life care: home, hospital or freestanding hospice?
    Alisha Kassam
    Division of Hematology Oncology, Department of Pediatrics, The Hospital for Sick Children, University of Toronto, Toronto, Canada Division of Palliative Medicine, Department of Medicine, Southlake Regional Health Centre, Newmarket, Canada
    Pediatr Blood Cancer 61:859-64. 2014
  5. doi Classification of treatment-related mortality in children with cancer: a systematic assessment
    Sarah Alexander
    Division of Haematology Oncology, The Hospital for Sick Children, Toronto, ON, Canada
    Lancet Oncol 16:e604-10. 2015
  6. doi Quality of life during active treatment for pediatric acute lymphoblastic leukemia
    Lillian Sung
    Division of Haematology Oncology, Department of Paediatrics, The Hospital for Sick Children and Department of Paediatrics, University of Toronto, Toronto, ON, Canada
    Int J Cancer 128:1213-20. 2011
  7. ncbi A Feasibility Pilot Trial of Individualized Homeopathic Treatment of Fatigue in Children Receiving Chemotherapy
    David Brule
    University of Toronto, Toronto, ON, Canada
    Integr Cancer Ther 15:495-501. 2016
  8. doi Differences in end-of-life communication for children with advanced cancer who were referred to a palliative care team
    Alisha Kassam
    Department of Pediatrics, Division of Haematology Oncology, The Hospital for Sick Children, Toronto, Canada
    Pediatr Blood Cancer 62:1409-13. 2015
  9. doi Cardioprotection and Second Malignant Neoplasms Associated With Dexrazoxane in Children Receiving Anthracycline Chemotherapy: A Systematic Review and Meta-Analysis
    Furqan Shaikh
    Division of Haematology Oncology FS, LLD, SA, AG, PCN and Division of Cardiology LM, Hospital for Sick Children, Toronto, Ontario, Canada
    J Natl Cancer Inst 108:. 2016
  10. doi Olanzapine for treatment and prevention of acute chemotherapy-induced vomiting in children: a retrospective, multi-center review
    Jacqueline Flank
    Department of Pharmacy, The Hospital for Sick Children, Toronto, Canada Leslie Dan Faculty of Pharmacy, University of Toronto, Toronto, Canada
    Pediatr Blood Cancer 62:496-501. 2015

Collaborators

Detail Information

Publications15

  1. pmc Prevention of bacterial infection in pediatric oncology: what do we know, what can we learn?
    Sarah Alexander
    Division of Hematology Oncology, Hospital for Sick Children, Toronto, Ontario, Canada
    Pediatr Blood Cancer 59:16-20. 2012
    ..This paper will review the current literature on the use and risks of antimicrobial prophylaxis as well as non-pharmacological methods for infection prevention and will address areas in need of further research...
  2. doi Rituximab and desensitization for a patient with severe factor IX deficiency, inhibitors, and history of anaphylaxis
    Sarah Alexander
    Division of Paediatric Haematology, University of Toronto, Toronto, Ontario, Canada
    J Pediatr Hematol Oncol 30:93-5. 2008
    ..A second course of rituximab was given 13 months later for worsening FIX kinetics again with an excellent response and without evidence of adverse effects...
  3. doi Evaluation of treatment-related mortality among paediatric cancer deaths: a population based analysis
    Jason D Pole
    Pediatric Oncology Group of Ontario, 480 University Ave, Toronto, Ontario, M5G 1V2, Canada
    Br J Cancer . 2017
    ..Objectives were to describe the proportion of deaths due to treatment-related mortality (TRM) and to identify risk factors and probable causes of TRM among paediatric cancer deaths in a population-based cohort...
  4. doi Parent and clinician preferences for location of end-of-life care: home, hospital or freestanding hospice?
    Alisha Kassam
    Division of Hematology Oncology, Department of Pediatrics, The Hospital for Sick Children, University of Toronto, Toronto, Canada Division of Palliative Medicine, Department of Medicine, Southlake Regional Health Centre, Newmarket, Canada
    Pediatr Blood Cancer 61:859-64. 2014
    ..However, access to these options varies greatly depending on geographical location. We aimed to determine bereaved parent and clinician preferences for location to EOL care and death...
  5. doi Classification of treatment-related mortality in children with cancer: a systematic assessment
    Sarah Alexander
    Division of Haematology Oncology, The Hospital for Sick Children, Toronto, ON, Canada
    Lancet Oncol 16:e604-10. 2015
    ..Our approach should allow comparison of treatment-related mortality across trials and across time. ..
  6. doi Quality of life during active treatment for pediatric acute lymphoblastic leukemia
    Lillian Sung
    Division of Haematology Oncology, Department of Paediatrics, The Hospital for Sick Children and Department of Paediatrics, University of Toronto, Toronto, ON, Canada
    Int J Cancer 128:1213-20. 2011
    ..Age and gender predicted QoL in high-risk ALL, whereas socioeconomics predicted QoL in standard-risk ALL. Future efforts should focus on longitudinal studies that describe QoL over time within individual patients...
  7. ncbi A Feasibility Pilot Trial of Individualized Homeopathic Treatment of Fatigue in Children Receiving Chemotherapy
    David Brule
    University of Toronto, Toronto, ON, Canada
    Integr Cancer Ther 15:495-501. 2016
    ..Fatigue is a major problem in children with cancer. The objective was to examine the feasibility of performing a clinical trial of homeopathic treatment for fatigue in children receiving chemotherapy...
  8. doi Differences in end-of-life communication for children with advanced cancer who were referred to a palliative care team
    Alisha Kassam
    Department of Pediatrics, Division of Haematology Oncology, The Hospital for Sick Children, Toronto, Canada
    Pediatr Blood Cancer 62:1409-13. 2015
    ..We aimed to determine whether there was an association between specialist palliative care involvement and improved end-of-life communication for children with advanced cancer and their families...
  9. doi Cardioprotection and Second Malignant Neoplasms Associated With Dexrazoxane in Children Receiving Anthracycline Chemotherapy: A Systematic Review and Meta-Analysis
    Furqan Shaikh
    Division of Haematology Oncology FS, LLD, SA, AG, PCN and Division of Cardiology LM, Hospital for Sick Children, Toronto, Ontario, Canada
    J Natl Cancer Inst 108:. 2016
    ..This study aimed to systematically review the evidence regarding dexrazoxane in children...
  10. doi Olanzapine for treatment and prevention of acute chemotherapy-induced vomiting in children: a retrospective, multi-center review
    Jacqueline Flank
    Department of Pharmacy, The Hospital for Sick Children, Toronto, Canada Leslie Dan Faculty of Pharmacy, University of Toronto, Toronto, Canada
    Pediatr Blood Cancer 62:496-501. 2015
    ..This retrospective review provides preliminary data regarding the safety and efficacy of olanzapine for chemotherapy-induced vomiting (CIV) control in children...
  11. pmc Attitudes toward infection prophylaxis in pediatric oncology: a qualitative approach
    Caroline Diorio
    Program in Child Health Evaluative Sciences, The Hospital for Sick Children, Toronto, Ontario, Canada
    PLoS ONE 7:e47815. 2012
    ..The purpose of this report was to describe the attitudes of parents, children and healthcare professionals to infection prophylaxis in pediatric oncology...
  12. doi Moving toward quality palliative cancer care: parent and clinician perspectives on gaps between what matters and what is accessible
    Alisha Kassam
    Hospital for Sick Children, Ontario, Canada
    J Clin Oncol 31:910-5. 2013
    ..We aimed to determine which elements of palliative care are considered important according to bereaved parents and pediatric oncology clinicians and to determine accessibility of these elements...
  13. pmc Lack of treatment-related mortality definitions in clinical trials of children, adolescents and young adults with lymphomas, solid tumors and brain tumors: a systematic review
    Thai Hoa Tran
    Division of Haematology Oncology, The Hospital for Sick Children, 555 University Ave, Toronto, Ontario M5G 1X8, Canada
    BMC Cancer 14:612. 2014
    ..Our objective was to describe TRM definitions used in studies of children, adolescents and young adults with lymphomas, solid tumors and brain tumors...
  14. doi The risk of traumatic lumbar punctures in children with acute lymphoblastic leukaemia
    Furqan Shaikh
    Division of Haematology Oncology, The Hospital for Sick Children and University of Toronto, Toronto, Ontario, Canada Electronic address
    Eur J Cancer 50:1482-9. 2014
    ..Traumatic lumbar punctures with blasts (TLP+) in children with acute lymphoblastic leukaemia (ALL) obscure central nervous system status and are associated with a poorer event-free survival (EFS)...
  15. doi Methylnaltrexone for opioid-induced constipation in pediatric oncology patients
    Amelia Rodrigues
    Department of Pharmacy, The Hospital for Sick Children, Toronto, Canada
    Pediatr Blood Cancer 60:1667-70. 2013
    ..Published literature on the use of methylnaltrexone in children is very limited. This retrospective review describes the effectiveness and safety of methylnaltrexone for opioid-induced constipation in pediatric oncology patients...