Affiliation: The Hospital for Sick Children
- Prevention of bacterial infection in pediatric oncology: what do we know, what can we learn?Sarah Alexander
Division of Hematology Oncology, Hospital for Sick Children, Toronto, Ontario, Canada
Pediatr Blood Cancer 59:16-20. 2012..This paper will review the current literature on the use and risks of antimicrobial prophylaxis as well as non-pharmacological methods for infection prevention and will address areas in need of further research...
- Rituximab and desensitization for a patient with severe factor IX deficiency, inhibitors, and history of anaphylaxisSarah Alexander
Division of Paediatric Haematology, University of Toronto, Toronto, Ontario, Canada
J Pediatr Hematol Oncol 30:93-5. 2008..A second course of rituximab was given 13 months later for worsening FIX kinetics again with an excellent response and without evidence of adverse effects...
- Evaluation of treatment-related mortality among paediatric cancer deaths: a population based analysisJason D Pole
Pediatric Oncology Group of Ontario, 480 University Ave, Toronto, Ontario, M5G 1V2, Canada
Br J Cancer . 2017..Objectives were to describe the proportion of deaths due to treatment-related mortality (TRM) and to identify risk factors and probable causes of TRM among paediatric cancer deaths in a population-based cohort...
- Parent and clinician preferences for location of end-of-life care: home, hospital or freestanding hospice?Alisha Kassam
Division of Hematology Oncology, Department of Pediatrics, The Hospital for Sick Children, University of Toronto, Toronto, Canada Division of Palliative Medicine, Department of Medicine, Southlake Regional Health Centre, Newmarket, Canada
Pediatr Blood Cancer 61:859-64. 2014..However, access to these options varies greatly depending on geographical location. We aimed to determine bereaved parent and clinician preferences for location to EOL care and death...
- Classification of treatment-related mortality in children with cancer: a systematic assessmentSarah Alexander
Division of Haematology Oncology, The Hospital for Sick Children, Toronto, ON, Canada
Lancet Oncol 16:e604-10. 2015..Our approach should allow comparison of treatment-related mortality across trials and across time. ..
- Quality of life during active treatment for pediatric acute lymphoblastic leukemiaLillian Sung
Division of Haematology Oncology, Department of Paediatrics, The Hospital for Sick Children and Department of Paediatrics, University of Toronto, Toronto, ON, Canada
Int J Cancer 128:1213-20. 2011..Age and gender predicted QoL in high-risk ALL, whereas socioeconomics predicted QoL in standard-risk ALL. Future efforts should focus on longitudinal studies that describe QoL over time within individual patients...
- A Feasibility Pilot Trial of Individualized Homeopathic Treatment of Fatigue in Children Receiving ChemotherapyDavid Brule
University of Toronto, Toronto, ON, Canada
Integr Cancer Ther 15:495-501. 2016..Fatigue is a major problem in children with cancer. The objective was to examine the feasibility of performing a clinical trial of homeopathic treatment for fatigue in children receiving chemotherapy...
- Differences in end-of-life communication for children with advanced cancer who were referred to a palliative care teamAlisha Kassam
Department of Pediatrics, Division of Haematology Oncology, The Hospital for Sick Children, Toronto, Canada
Pediatr Blood Cancer 62:1409-13. 2015..We aimed to determine whether there was an association between specialist palliative care involvement and improved end-of-life communication for children with advanced cancer and their families...
- Cardioprotection and Second Malignant Neoplasms Associated With Dexrazoxane in Children Receiving Anthracycline Chemotherapy: A Systematic Review and Meta-AnalysisFurqan Shaikh
Division of Haematology Oncology FS, LLD, SA, AG, PCN and Division of Cardiology LM, Hospital for Sick Children, Toronto, Ontario, Canada
J Natl Cancer Inst 108:. 2016..This study aimed to systematically review the evidence regarding dexrazoxane in children...
- Olanzapine for treatment and prevention of acute chemotherapy-induced vomiting in children: a retrospective, multi-center reviewJacqueline Flank
Department of Pharmacy, The Hospital for Sick Children, Toronto, Canada Leslie Dan Faculty of Pharmacy, University of Toronto, Toronto, Canada
Pediatr Blood Cancer 62:496-501. 2015..This retrospective review provides preliminary data regarding the safety and efficacy of olanzapine for chemotherapy-induced vomiting (CIV) control in children...
- Attitudes toward infection prophylaxis in pediatric oncology: a qualitative approachCaroline Diorio
Program in Child Health Evaluative Sciences, The Hospital for Sick Children, Toronto, Ontario, Canada
PLoS ONE 7:e47815. 2012..The purpose of this report was to describe the attitudes of parents, children and healthcare professionals to infection prophylaxis in pediatric oncology...
- Moving toward quality palliative cancer care: parent and clinician perspectives on gaps between what matters and what is accessibleAlisha Kassam
Hospital for Sick Children, Ontario, Canada
J Clin Oncol 31:910-5. 2013..We aimed to determine which elements of palliative care are considered important according to bereaved parents and pediatric oncology clinicians and to determine accessibility of these elements...
- Lack of treatment-related mortality definitions in clinical trials of children, adolescents and young adults with lymphomas, solid tumors and brain tumors: a systematic reviewThai Hoa Tran
Division of Haematology Oncology, The Hospital for Sick Children, 555 University Ave, Toronto, Ontario M5G 1X8, Canada
BMC Cancer 14:612. 2014..Our objective was to describe TRM definitions used in studies of children, adolescents and young adults with lymphomas, solid tumors and brain tumors...
- The risk of traumatic lumbar punctures in children with acute lymphoblastic leukaemiaFurqan Shaikh
Division of Haematology Oncology, The Hospital for Sick Children and University of Toronto, Toronto, Ontario, Canada Electronic address
Eur J Cancer 50:1482-9. 2014..Traumatic lumbar punctures with blasts (TLP+) in children with acute lymphoblastic leukaemia (ALL) obscure central nervous system status and are associated with a poorer event-free survival (EFS)...
- Methylnaltrexone for opioid-induced constipation in pediatric oncology patientsAmelia Rodrigues
Department of Pharmacy, The Hospital for Sick Children, Toronto, Canada
Pediatr Blood Cancer 60:1667-70. 2013..Published literature on the use of methylnaltrexone in children is very limited. This retrospective review describes the effectiveness and safety of methylnaltrexone for opioid-induced constipation in pediatric oncology patients...