Oussama Abla

Summary

Affiliation: The Hospital for Sick Children
Country: Canada

Publications

  1. doi request reprint Langerhans cell histiocytosis: Current concepts and treatments
    Oussama Abla
    Department of Paediatrics, The Hospital for Sick Children, Toronto, Ontario, Canada
    Cancer Treat Rev 36:354-9. 2010
  2. ncbi request reprint Leptomeningeal precursor B-cell lymphoblastic lymphoma in a child with minimal bone marrow involvement
    Oussama Abla
    University of Toronto, Division of Hematology Oncology, The Hospital for Sick Children, ON, Canada
    J Pediatr Hematol Oncol 26:469-72. 2004
  3. ncbi request reprint A case series of pediatric primary central nervous system lymphoma: favorable outcome without cranial irradiation
    Oussama Abla
    Division of Hematology Oncology, The Hospital for Sick Children, Toronto, Ontario, Canada
    Pediatr Blood Cancer 47:880-5. 2006
  4. ncbi request reprint bcr-abl-positive T-cell acute lymphoblastic leukemia associated with parvovirus B19 infection
    Oussama Abla
    The Hospital for Sick Children, Toronto, Ontario, Canada
    J Pediatr Hematol Oncol 28:98-9. 2006
  5. pmc Primary CNS lymphoma in children and adolescents: a descriptive analysis from the International Primary CNS Lymphoma Collaborative Group (IPCG)
    Oussama Abla
    Division of Haematology Oncology, Department of Paediatrics, Hospital for Sick Children, University of Toronto, Toronto, Canada
    Clin Cancer Res 17:346-52. 2011
  6. doi request reprint Anaplastic large cell lymphoma of the ovary in a pediatric patient
    Amy Lee Chong
    Department of Paediatrics Division of Haematology Oncology, The Hospital for Sick Children, Toronto, Ontario, Canada
    J Pediatr Hematol Oncol 31:702-4. 2009
  7. doi request reprint Hemophagocytic lymphohistiocytosis onset during induction therapy for precursor B-cell acute lymphoblastic leukemia
    Vicky R Breakey
    Division of Pediatric Haematology and Oncology, Department of Paediatric Medicine, Hospital for Sick Children, Toronto, Canada
    J Pediatr Hematol Oncol 30:956-8. 2008
  8. ncbi request reprint Predictors of viridans streptococcal shock syndrome in bacteremic children with cancer and stem-cell transplant recipients
    Adam Gassas
    Department of Pediatrics, Hospital for Sick Children, Toronto, Ontario, Canada
    J Clin Oncol 22:1222-7. 2004
  9. doi request reprint Isolated central nervous system relapse in childhood acute promyelocytic leukemia
    Katrin Scheinemann
    Division of Hematology Oncology, The Hospital for Sick Children, Toronto, Ontario, Canada
    J Pediatr Hematol Oncol 30:160-2. 2008
  10. doi request reprint Frequency and outcome of pediatric acute lymphoblastic leukemia with ZNF384 gene rearrangements including a novel translocation resulting in an ARID1B/ZNF384 gene fusion
    Mary Shago
    Department of Paediatric Laboratory Medicine, The Hospital for Sick Children, Toronto, Ontario, Canada
    Pediatr Blood Cancer 63:1915-21. 2016

Collaborators

Detail Information

Publications34

  1. doi request reprint Langerhans cell histiocytosis: Current concepts and treatments
    Oussama Abla
    Department of Paediatrics, The Hospital for Sick Children, Toronto, Ontario, Canada
    Cancer Treat Rev 36:354-9. 2010
    ..Due to the rarity of LCH in children and adults, patients must be enrolled on multi-national clinical trials, whenever possible, to advance our knowledge of the optimal therapeutic strategies and long-term outcomes...
  2. ncbi request reprint Leptomeningeal precursor B-cell lymphoblastic lymphoma in a child with minimal bone marrow involvement
    Oussama Abla
    University of Toronto, Division of Hematology Oncology, The Hospital for Sick Children, ON, Canada
    J Pediatr Hematol Oncol 26:469-72. 2004
    ..This patient was treated on a high-risk ALL protocol with intensive systemic/intrathecal chemotherapy plus cranial irradiation, and he remained in complete remission 6 months after his initial diagnosis...
  3. ncbi request reprint A case series of pediatric primary central nervous system lymphoma: favorable outcome without cranial irradiation
    Oussama Abla
    Division of Hematology Oncology, The Hospital for Sick Children, Toronto, Ontario, Canada
    Pediatr Blood Cancer 47:880-5. 2006
    ..To describe the outcome of childhood primary central nervous system lymphoma (PCNSL) treated with chemotherapy alone or with chemotherapy plus cranial radiotherapy (CRT)...
  4. ncbi request reprint bcr-abl-positive T-cell acute lymphoblastic leukemia associated with parvovirus B19 infection
    Oussama Abla
    The Hospital for Sick Children, Toronto, Ontario, Canada
    J Pediatr Hematol Oncol 28:98-9. 2006
    ..He died 8 months after transplant due to idiopathic pneumonia syndrome, but without evidence of relapsed disease...
  5. pmc Primary CNS lymphoma in children and adolescents: a descriptive analysis from the International Primary CNS Lymphoma Collaborative Group (IPCG)
    Oussama Abla
    Division of Haematology Oncology, Department of Paediatrics, Hospital for Sick Children, University of Toronto, Toronto, Canada
    Clin Cancer Res 17:346-52. 2011
    ..To describe the demographic and clinical features and outcomes for children and adolescents with primary CNS lymphoma (PCNSL)...
  6. doi request reprint Anaplastic large cell lymphoma of the ovary in a pediatric patient
    Amy Lee Chong
    Department of Paediatrics Division of Haematology Oncology, The Hospital for Sick Children, Toronto, Ontario, Canada
    J Pediatr Hematol Oncol 31:702-4. 2009
    ..We describe the unusual case of a 14-year-old adolescent with a locally disseminated ovarian anaplastic large-cell lymphoma, treated with surgery followed by chemotherapy, and who remains disease free at 2 years after diagnosis...
  7. doi request reprint Hemophagocytic lymphohistiocytosis onset during induction therapy for precursor B-cell acute lymphoblastic leukemia
    Vicky R Breakey
    Division of Pediatric Haematology and Oncology, Department of Paediatric Medicine, Hospital for Sick Children, Toronto, Canada
    J Pediatr Hematol Oncol 30:956-8. 2008
    ..His symptoms improved significantly after an increased dosage of steroids...
  8. ncbi request reprint Predictors of viridans streptococcal shock syndrome in bacteremic children with cancer and stem-cell transplant recipients
    Adam Gassas
    Department of Pediatrics, Hospital for Sick Children, Toronto, Ontario, Canada
    J Clin Oncol 22:1222-7. 2004
    ....
  9. doi request reprint Isolated central nervous system relapse in childhood acute promyelocytic leukemia
    Katrin Scheinemann
    Division of Hematology Oncology, The Hospital for Sick Children, Toronto, Ontario, Canada
    J Pediatr Hematol Oncol 30:160-2. 2008
    ..The patient remains in molecular remission at 9 months after autologous stem cell transplant. Prognostic factors of CNS relapse in children with APL are needed to define the indications for CNS prophylaxis in this group of patients...
  10. doi request reprint Frequency and outcome of pediatric acute lymphoblastic leukemia with ZNF384 gene rearrangements including a novel translocation resulting in an ARID1B/ZNF384 gene fusion
    Mary Shago
    Department of Paediatric Laboratory Medicine, The Hospital for Sick Children, Toronto, Ontario, Canada
    Pediatr Blood Cancer 63:1915-21. 2016
    ..ZNF384 gene rearrangements with multiple partner genes are recurrent in acute leukemia and are most often associated with a precursor B cell immunophenotype. The overall incidence of this genetic category of leukemia is uncertain...
  11. doi request reprint Early Complications of Hyperleukocytosis and Leukapheresis in Childhood Acute Leukemias
    Oussama Abla
    Leukemia Lymphoma Section, Department of Pediatrics, Division of Haematology Oncology, The Hospital for Sick Children, University of Toronto, Toronto, ON, Canada Pediatric Department, Pediatric Oncology Hematology Division, Tawam Hospital, Al Ain, United Arab Emirates
    J Pediatr Hematol Oncol 38:111-7. 2016
    ..The role of leukapheresis as a cytoreductive procedure in childhood hyperleukocytic leukemia remains to be well defined...
  12. doi request reprint Human metapneumovirus (hMPV) infection in children with cancer
    Muhammad Ali
    Division of Hematology Oncology, The Hospital for Sick Children, Toronto, ON, Canada
    J Pediatr Hematol Oncol 35:444-6. 2013
    ..Infections may result in significant disease but is usually not fatal. In the absence of specific anti-viral drug, good symptomatic therapy appears to be the optimal therapy. ..
  13. doi request reprint Association between obesity at diagnosis and weight change during induction and survival in pediatric acute lymphoblastic leukemia
    Marie Chantal Ethier
    Child Health Evaluative Sciences, The Hospital for Sick Children, Toronto, ON, Canada
    Leuk Lymphoma 53:1677-81. 2012
    ..74-0.90; p <0.0001). Obese pediatric patients with ALL have inferior survival while increased weight during induction may be associated with better survival. Causes of weight loss during induction should be aggressively managed...
  14. ncbi request reprint Primary central nervous system lymphoma in children
    Oussama Abla
    Division of Hematology Oncology, The Hospital for Sick Children and Department of Paediatrics, University of Toronto, Ontario, Canada
    Neurosurg Focus 21:E8. 2006
    ..Further progress in the management of childhood PCNSL will require prospective multinational studies...
  15. doi request reprint Risk factors for infection-related outcomes during induction therapy for childhood acute lymphoblastic leukemia
    Samina Afzal
    Division of Haematology Oncology, The Hospital for Sick Children, Toronto, Ontario, Canada
    Pediatr Infect Dis J 28:1064-8. 2009
    ..The secondary objectives were to describe risk factors for microbiologically documented infections and for patients with a febrile episode, to identify risk factors for recurrence of fever or reinitiation of antibiotics...
  16. doi request reprint Underlying undiagnosed inherited marrow failure syndromes among children with cancer
    Fahad Alabbas
    Marrow Failure and Myelodysplasia Program, Division of Haematology and Oncology, Department of Paediatrics, The Hospital for Sick Children, University of Toronto, Toronto, Ontario, Canada
    Pediatr Blood Cancer . 2016
    ..We conclude that a small fraction of patients with cancer have clinical features that indicate investigations to rule out underlying IBMFSs. A prospective study is needed to determine their prevalence...
  17. doi request reprint Lumbar spinal fluid collections in children treated with intrathecal chemotherapy: elevated CSF protein as a diagnostic clue
    Fahd Almanjomi
    Division of Haematology Oncology, Department of Diagnostic Imaging, The Hospital for Sick Children, Toronto, Ontario, Canada
    Pediatr Blood Cancer 51:295-8. 2008
    ..Awareness and detection of this complication by imaging is important because of its potential to interfere with effective CNS-directed chemotherapy of ALL...
  18. doi request reprint Sevelamer hydrochloride: a novel treatment of hyperphosphatemia associated with tumor lysis syndrome in children
    Shaker Abdullah
    Divisions of Hematology Oncology, The Hospital for Sick Children, Toronto, Canada
    Pediatr Blood Cancer 51:59-61. 2008
    ..Sevelamer is a phosphate-binder used effectively for the treatment of hyperphosphatemia in patients treated with dialysis...
  19. ncbi request reprint Features at presentation predict children with acute lymphoblastic leukemia at low risk for tumor lysis syndrome
    Tony H Truong
    Division of Hematology Oncology, The Hospital for Sick Children, University of Toronto, Toronto, Ontario, Canada
    Cancer 110:1832-9. 2007
    ..The objectives of the current study were 1) to describe the prevalence and predictors of TLS in childhood ALL and 2) to develop a sensitive prediction rule to identify patients at lower risk of TLS...
  20. ncbi request reprint Childhood myeloid/natural killer precursor acute leukemia with novel chromosomal aberrations der(5)t(4;5)(q31;q31.3) and t(14;17)(q32;q23)
    Mohamed Abdelhaleem
    Division of Haematopathology, Department of Paediatric Laboratory Medicine, Room 3691, Atrium, Hospital for Sick Children, Toronto, Ontario, Canada
    Cancer Genet Cytogenet 178:141-3. 2007
    ..3) and t(14;17)(q32;q23), not previously described in childhood acute leukemia. The patient achieved morphological remission following myeloid-based leukemia therapy...
  21. doi request reprint Safety and efficacy of intrathecal rituximab in children with B cell lymphoid CD20+ malignancies: An international retrospective study
    Francesco Ceppi
    Department of Pediatrics, Division of Hematology Oncology, Hospital for Sick Children, Ontario, Toronto, Canada
    Am J Hematol 91:486-91. 2016
    ..Prospective trials of IT/intraventricular rituximab for patients with CNS involvement of CD20 + B lymphoid malignancies are warranted...
  22. pmc Bisphosphonates in Langerhans Cell Histiocytosis: An International Retrospective Case Series
    Deepak Chellapandian
    Division of Hematology Oncology and Bone Marrow Transplantation, Department of Pediatrics, The Hospital for Sick Children SickKids, University of Toronto, Toronto, Ontario, Canada
    Mediterr J Hematol Infect Dis 8:e2016033. 2016
    ..Bisphosphonates are osteoclast inhibitors that have shown to be helpful in treating bone lesions of LCH. To date, there are no large international studies to describe their role in treating bone lesions of LCH...
  23. ncbi request reprint Hepatosplenic gammadelta T-cell lymphoma in a 10-year-old boy successfully treated with hematopoietic stem cell transplantation
    Adam Gassas
    Division of Hematology Oncology, Department of Pediatrics, The Hospital for Sick Children, University of Toronto, Ontario, Canada
    Am J Hematol 75:113-4. 2004
    ..Conventional multi-agent chemotherapy appears to be inadequate for cure. This is the first report with this type of lymphoma in a boy less than 15 years old treated with hematopoietic stem cell transplantation (HSCT)...
  24. doi request reprint Hepatitis-associated aplastic anemia presenting as a familial bone marrow failure syndrome
    Vicky Rowena Breakey
    Department of Pediatrics, Division of Pediatric Hematology and Oncology, Research Institute, Hospital for Sick Children, University of Toronto, Toronto, Ontario, Canada
    J Pediatr Hematol Oncol 31:884-7. 2009
    ..These familial cases raise the possibility of an inherited bone marrow failure syndrome and suggest that severe hepatitis-associated aplastic anemia may not be always an acquired condition...
  25. doi request reprint Primary Effusion Lymphoma (PEL)-Like Lymphoma in a Child With Congenital Immunodeficiency
    Grace K S Lam
    Division of Haematology Oncology, The Hospital for Sick Children, Toronto, Ontario, Canada
    Pediatr Blood Cancer 63:1674-6. 2016
    ..This is the first reported pediatric case of PEL-like lymphoma. Increased diagnostic awareness and more effective treatment strategies are needed for this rare lymphoma. ..
  26. doi request reprint Primary Cutaneous Lymphomas in Children and Adolescents
    Francesco Ceppi
    Division of Hematology Oncology, Department of Pediatrics, Hospital for Sick Children, Ontario, Toronto, Canada
    Pediatr Blood Cancer 63:1886-94. 2016
    ....
  27. doi request reprint Treatment of Langerhans cell histiocytosis: role of BRAF/MAPK inhibition
    Oussama Abla
    Division of Haematology Oncology, Department of Pediatrics, The Hospital for Sick Children, Toronto, ON, Canada
    Hematology Am Soc Hematol Educ Program 2015:565-70. 2015
    ....
  28. doi request reprint Treatment of young children with CNS-positive acute lymphoblastic leukemia without cranial radiotherapy
    Marta Wilejto
    Division of Haematology Oncology, Department of Paediatrics, The Hospital for Sick Children, Toronto, Canada
    Pediatr Blood Cancer 62:1881-5. 2015
    ..For patients with central nervous system (CNS) involvement with ALL at diagnosis, the use of CRT remains common. Children <5 years of age are a particularly challenging subgroup in whom the consequences of CRT can be devastating...
  29. ncbi request reprint Childhood acute lymphoblastic leukaemia simulating multifocal osteomyelitis
    Sandip Bartakke
    Paediatric Haematology Oncology, Hospital for Sick Children, Toronto, ON, Canada
    Br J Haematol 139:2. 2007
  30. doi request reprint Severe neutropenia at time of port insertion is not a risk factor for catheter-associated infections in children with acute lymphoblastic leukemia
    Beatriz L P Junqueira
    Department of Diagnostic Imaging Image Guided Therapy Center, The Hospital for Sick Children, Toronto, Ontario, Canada
    Cancer 116:4368-75. 2010
    ..The objective of this study was to determine whether severe neutropenia on the day of port-a-catheter (PORT) insertion was a risk factor for catheter-associated infection (CAI) in children with acute lymphoblastic leukemia (ALL)...
  31. doi request reprint Coadministration of propofol and remifentanil for lumbar puncture in children: dose-response and an evaluation of two dose combinations
    Jason A Hayes
    Department of Anesthesia, The Hospital for Sick Children, 555 University Avenue, Toronto, Ontario, Canada
    Anesthesiology 109:613-8. 2008
    ..The authors undertook a two-part study to evaluate coadministration of propofol and remifentanil as an anesthetic technique for lumbar puncture in children...
  32. ncbi request reprint TEL-AML1 fusion in acute lymphoblastic leukemia with L3 morphology
    Mohamed Abdelhaleem
    Pediatr Blood Cancer 49:217. 2007
  33. ncbi request reprint Acute lymphoblastic leukemia with massive myelofibrosis
    Oussama Abla
    J Pediatr Hematol Oncol 28:633-4. 2006
  34. ncbi request reprint Translocation (X;10) in a child with therapy-related acute myeloid leukemia following chemotherapy for Ewing's Sarcoma
    Oussama Abla
    Cancer Genet Cytogenet 178:168-9. 2007