Laurie J Morrison

Summary

Affiliation: Sunnybrook Health Sciences Centre
Country: Canada

Publications

  1. ncbi request reprint A randomized controlled feasibility trial comparing safety and effectiveness of prehospital pacing versus conventional treatment: 'PrePACE'
    Laurie J Morrison
    Prehospital and Transport Medicine Research Program, Sunnybrook Health Sciences Centre, Toronto, Ont, Canada
    Resuscitation 76:341-9. 2008
  2. ncbi request reprint Derivation and evaluation of a termination of resuscitation clinical prediction rule for advanced life support providers
    Laurie J Morrison
    Prehospital and Transport Medicine Research Program, Sunnybrook Health Sciences Centre, 2075 Bayview Avenue, Toronto, Ontario, M4N 3M5 Canada
    Resuscitation 74:266-75. 2007
  3. ncbi request reprint Inter-rater reliability and comfort in the application of a basic life support termination of resuscitation clinical prediction rule for out of hospital cardiac arrest
    Laurie J Morrison
    Prehospital and Transport Medicine Research Program, Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada
    Resuscitation 74:150-7. 2007
  4. doi request reprint Validation of a universal prehospital termination of resuscitation clinical prediction rule for advanced and basic life support providers
    Laurie J Morrison
    Prehospital and Transport Medicine Research Program, Rescu, Keenan Research Centre, Li Ka Shing Knowledge Institute, St Michael s Hospital, Toronto, Ontario, Canada
    Resuscitation 80:324-8. 2009
  5. doi request reprint Termination of resuscitation: a guide to interpreting the literature
    Laurie J Morrison
    Prehospital and Transport Medicine Research Program, Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada
    Resuscitation 79:387-90. 2008
  6. pmc Rationale, development and implementation of the Resuscitation Outcomes Consortium Epistry-Cardiac Arrest
    Laurie J Morrison
    Prehospital and Transport Medicine Research Program, Sunnybrook and Women s College Health Sciences Centre, 2075 Bayview Avenue, Suite C753, Toronto, Ontario, Canada M4N 3M5
    Resuscitation 78:161-9. 2008
  7. ncbi request reprint Validation of a rule for termination of resuscitation in out-of-hospital cardiac arrest
    Laurie J Morrison
    Prehospital and Transport Medicine Research Program, Sunnybrook and Women s College Health Sciences Centre, Toronto, Ont, Canada
    N Engl J Med 355:478-87. 2006
  8. pmc Knowledge translation in emergency medical services: a qualitative survey of barriers to guideline implementation
    Blair L Bigham
    Rescu, Keenan Research Centre, Li Ka Shing Knowledge Institute, St Michael s Hospital, University of Toronto, Toronto, Canada
    Resuscitation 81:836-40. 2010
  9. doi request reprint The Toronto prehospital hypertonic resuscitation--head injury and multiorgan dysfunction trial: feasibility study of a randomized controlled trial
    Laurie J Morrison
    Rescu, Keenan Research Centre, Li Ka Shing Knowledge Institute, St Michael s Hospital, Ontario, Canada
    J Crit Care 26:363-72. 2011
  10. pmc Cardiac arrest survival did not increase in the Resuscitation Outcomes Consortium after implementation of the 2005 AHA CPR and ECC guidelines
    Blair L Bigham
    Rescu, Keenan Research Centre, Li Ka Shing Knowledge Institute, St Michael s Hospital, University of Toronto, 30 Bond Street, Toronto, ON M5B1W8, Canada
    Resuscitation 82:979-83. 2011

Detail Information

Publications84

  1. ncbi request reprint A randomized controlled feasibility trial comparing safety and effectiveness of prehospital pacing versus conventional treatment: 'PrePACE'
    Laurie J Morrison
    Prehospital and Transport Medicine Research Program, Sunnybrook Health Sciences Centre, Toronto, Ont, Canada
    Resuscitation 76:341-9. 2008
    ..To evaluate the feasibility of a prehospital randomized controlled trial comparing transcutaneous pacing (TCP) with dopamine for unstable bradycardia...
  2. ncbi request reprint Derivation and evaluation of a termination of resuscitation clinical prediction rule for advanced life support providers
    Laurie J Morrison
    Prehospital and Transport Medicine Research Program, Sunnybrook Health Sciences Centre, 2075 Bayview Avenue, Toronto, Ontario, M4N 3M5 Canada
    Resuscitation 74:266-75. 2007
    ..Validation of a rule for termination of resuscitation in out-of-hospital cardiac arrest. N Engl J Med 2006;355(5):478-87] on the same cohort of patients for comparison purposes...
  3. ncbi request reprint Inter-rater reliability and comfort in the application of a basic life support termination of resuscitation clinical prediction rule for out of hospital cardiac arrest
    Laurie J Morrison
    Prehospital and Transport Medicine Research Program, Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada
    Resuscitation 74:150-7. 2007
    ....
  4. doi request reprint Validation of a universal prehospital termination of resuscitation clinical prediction rule for advanced and basic life support providers
    Laurie J Morrison
    Prehospital and Transport Medicine Research Program, Rescu, Keenan Research Centre, Li Ka Shing Knowledge Institute, St Michael s Hospital, Toronto, Ontario, Canada
    Resuscitation 80:324-8. 2009
    ..We sought to externally validate each rule on a prospective cohort of prehospital cardiac arrest patients to determine if either rule could be proposed as a universal prehospital termination of resuscitation rule...
  5. doi request reprint Termination of resuscitation: a guide to interpreting the literature
    Laurie J Morrison
    Prehospital and Transport Medicine Research Program, Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada
    Resuscitation 79:387-90. 2008
    ..Very few publish the EMS transport rate when the rule is applied; the outcome of interest to EMS services...
  6. pmc Rationale, development and implementation of the Resuscitation Outcomes Consortium Epistry-Cardiac Arrest
    Laurie J Morrison
    Prehospital and Transport Medicine Research Program, Sunnybrook and Women s College Health Sciences Centre, 2075 Bayview Avenue, Suite C753, Toronto, Ontario, Canada M4N 3M5
    Resuscitation 78:161-9. 2008
    ..To describe the development, design and consequent scientific implications of the Resuscitation Outcomes Consortium (ROC) population-based registry; ROC Epistry-Cardiac Arrest...
  7. ncbi request reprint Validation of a rule for termination of resuscitation in out-of-hospital cardiac arrest
    Laurie J Morrison
    Prehospital and Transport Medicine Research Program, Sunnybrook and Women s College Health Sciences Centre, Toronto, Ont, Canada
    N Engl J Med 355:478-87. 2006
    ..Otherwise, the rule recommends transportation to the hospital, in accordance with routine practice...
  8. pmc Knowledge translation in emergency medical services: a qualitative survey of barriers to guideline implementation
    Blair L Bigham
    Rescu, Keenan Research Centre, Li Ka Shing Knowledge Institute, St Michael s Hospital, University of Toronto, Toronto, Canada
    Resuscitation 81:836-40. 2010
    ..The American Heart Association (AHA) released guidelines to improve survival rates from out-of-hospital cardiac arrest in 2005. We sought to identify what barriers delayed the implementation of these guidelines in EMS agencies...
  9. doi request reprint The Toronto prehospital hypertonic resuscitation--head injury and multiorgan dysfunction trial: feasibility study of a randomized controlled trial
    Laurie J Morrison
    Rescu, Keenan Research Centre, Li Ka Shing Knowledge Institute, St Michael s Hospital, Ontario, Canada
    J Crit Care 26:363-72. 2011
    ..The aim of the study was to evaluate the feasibility of a prehospital trial comparing hypertonic saline and dextran (HSD) with normal saline (NS) in blunt head injury patients...
  10. pmc Cardiac arrest survival did not increase in the Resuscitation Outcomes Consortium after implementation of the 2005 AHA CPR and ECC guidelines
    Blair L Bigham
    Rescu, Keenan Research Centre, Li Ka Shing Knowledge Institute, St Michael s Hospital, University of Toronto, 30 Bond Street, Toronto, ON M5B1W8, Canada
    Resuscitation 82:979-83. 2011
    ..We examined the effect of the 2005 American Heart Association guidelines on survival in the Resuscitation Outcomes Consortium (ROC) Cardiac Arrest Epistry...
  11. ncbi request reprint Out-of-hospital cardiac arrest rectilinear biphasic to monophasic damped sine defibrillation waveforms with advanced life support intervention trial (ORBIT)
    Laurie J Morrison
    Prehospital and Transport Medicine Research Program, Sunnybrook and Women s College Health Sciences Centre, Institute for Clinical and Evaluative Sciences, Department of Medicine, University of Toronto, Toronto, Ont, Canada
    Resuscitation 66:149-57. 2005
    ..This effectiveness study compared monophasic and biphasic defibrillation waveform for conversion of ventricular arrhythmias in all OHCA treated with advance life support (ALS)...
  12. ncbi request reprint Emergency department gridlock and out-of-hospital delays for cardiac patients
    Michael J Schull
    Department of Emergency Services, Sunnybrook and Women s College Health Sciences Centre, Toronto, Ontario, Canada
    Acad Emerg Med 10:709-16. 2003
    ..To determine the effect of simultaneous ambulance diversion at multiple emergency departments (EDs) (gridlock) on transport delays for patients with chest pain...
  13. ncbi request reprint Rationale and design of the Trial of Routine ANgioplasty and Stenting After Fibrinolysis to Enhance Reperfusion in Acute Myocardial Infarction (TRANSFER-AMI)
    Warren J Cantor
    Southlake Regional Health Centre, Newmarket, Ontario, Canada
    Am Heart J 155:19-25. 2008
    ..The role of routine early PCI after fibrinolysis, using stents and contemporary pharmacotherapy, has not been studied in a large adequately powered randomized trial...
  14. pmc Prehospital resuscitation with hypertonic saline-dextran modulates inflammatory, coagulation and endothelial activation marker profiles in severe traumatic brain injured patients
    Shawn G Rhind
    Defence Research and Development Canada, Toronto, Canada
    J Neuroinflammation 7:5. 2010
    ..This study examined the impact of hypertonic fluids on inflammatory/coagulation cascades in isolated head injury...
  15. ncbi request reprint Prehospital triage and direct transport of patients with ST-elevation myocardial infarction to primary percutaneous coronary intervention centres: a systematic review and meta-analysis
    Steven C Brooks
    Rescu, Keenan Research Centre, Li Ka Shing Knowledge Institute, St Michael s Hospital, Toronto, Ontario
    CJEM 11:481-92. 2009
    ..We sought to determine whether direct transport of adult STEMI patients by emergency medical services to primary PCI centres improves 30-day all-cause mortality when compared with a strategy of transportation to the closest hospital...
  16. ncbi request reprint Emergency department contributors to ambulance diversion: a quantitative analysis
    Michael J Schull
    Clinical Epidemiology Unit and the Department of Emergency Services, Sunnybrook and Women s College Health Sciences Centre, Toronto, Ontario, Canada
    Ann Emerg Med 41:467-76. 2003
    ..We determine the relationship between physician, nursing, and patient factors on emergency department use of ambulance diversion...
  17. doi request reprint A citywide prehospital protocol increases access to stroke thrombolysis in Toronto
    David J Gladstone
    North and East GTA Ontario Regional Stroke Centre and Division of Neurology, Department of Medicine, and Brain Sciences Program, Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada
    Stroke 40:3841-4. 2009
    ..This report describes the initial impact of the activation protocol at our regional stroke center...
  18. doi request reprint Efficacy of early invasive management post-fibrinolysis in men versus women with ST-elevation myocardial infarction: a subgroup analysis from Trial of Routine Angioplasty and Stenting after Fibrinolysis to Enhance Reperfusion in Acute Myocardial Infarctio
    Vineet Bhan
    Terrence Donnelly Heart Centre, St Michael s Hospital, Toronto, Ontario, Canada
    Am Heart J 164:343-50. 2012
    ..However, it is not clear whether treatment efficacy differs between men and women...
  19. pmc Resuscitation Outcomes Consortium (ROC) PRIMED cardiac arrest trial methods part 2: rationale and methodology for "Analyze Later vs. Analyze Early" protocol
    Ian G Stiell
    Ottawa, Ontario, Canada
    Resuscitation 78:186-95. 2008
    ....
  20. pmc Delayed prehospital implementation of the 2005 American Heart Association guidelines for cardiopulmonary resuscitation and emergency cardiac care
    Blair L Bigham
    Rescu, Keenan Research Centre, Li Ka Shing Knowledge Institute, St Michael s Hospital, University of Toronto, Toronto, Ontario, Canada M5B1W8
    Prehosp Emerg Care 14:355-60. 2010
    ..In 2005, the American Heart Association (AHA) released guidelines to improve survival rates from out-of-hospital cardiac arrest (OHCA)...
  21. doi request reprint Factors associated with out-of-hospital cardiac arrest with pulseless electric activity: A population-based study
    Dennis T Ko
    Institute of Clinical Evaluative Sciences, Toronto, ON, Canada Schulich Heart Centre, Toronto, ON, Canada Department of Medicine, University of Toronto, Toronto, ON, Canada Electronic address
    Am Heart J 177:129-37. 2016
    ..Our main objective was to characterize out-of-hospital cardiac arrest patients by initial presenting rhythm and to evaluate independent determinants of PEA...
  22. doi request reprint Long-term Clinical Outcomes and Predictors for Survivors of Out-of-Hospital Cardiac Arrest
    Mony Shuvy
    Department of Medicine, Schulich Heart Centre, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, Ontario, Canada Institute for Clinical Evaluative Sciences, Toronto, Ontario, Canada Electronic address
    Resuscitation . 2017
    ..Our objectives were to assess the long-term outcomes and predictors of mortality for patients who survived OHCA...
  23. doi request reprint What is the optimal chest compression depth during out-of-hospital cardiac arrest resuscitation of adult patients?
    Ian G Stiell
    From the Department of Emergency Medicine and Ottawa Hospital Research Institute, University of Ottawa, Ottawa, Ontario, Canada I G S, C V Clinical Trials Center, Department of Biostatistics S P B, G N and Department of Medicine G N, University of Washington, Seattle, WA University of Washington Harborview Center for Prehospital Emergency Care, Seattle, WA G N Division of Emergency Medicine, Department of Family and Community Medicine S C, and Division of Emergency Medicine, Department of Medicine L J M, University of Toronto, Toronto, Ontario, Canada Rescu, Li Ka Shing Knowledge Institute, St Michael s Hospital, Toronto, Ontario, Canada S C, L J M Department of Emergency Medicine, University of Pittsburgh, Pittsburgh, PA C W C, D H Department of Emergency Medicine, University of British Columbia, Vancouver, British Columbia, Canada J C Department of Emergency Medicine, Medical College of Wisconsin, Milwaukee, WI T P A Department of Emergency Medicine, University of California, San Diego, CA D P D Camas Fire Department, Camas, WA C F Central Washington University, Ellensburg, University of Virginia
    Circulation 130:1962-70. 2014
    ..This target is based on limited evidence, and we sought to determine the optimal compression depth range...
  24. pmc Prehospital evaluation and economic analysis of different coronary syndrome treatment strategies--PREDICT--rationale, development and implementation
    Laurie J Morrison
    Rescue, Keenan Research Centre, Li Ka Shing Knowledge Institute, St Michael s Hospital, University of Toronto, Toronto, Ontario, Canada
    BMC Emerg Med 11:4. 2011
    ..The main objective is to compare prehospital care strategies for time to treatment and survival outcomes as well as cost effectiveness...
  25. doi request reprint The impact of hospital experience with out-of-hospital cardiac arrest patients on post cardiac arrest care
    Heather Worthington
    Department of Emergency Medicine, Queen s University, Kingston, Ontario, Canada Department of Public Health Sciences, Queen s University, Kingston, Ontario, Canada Electronic address
    Resuscitation . 2016
    ..We evaluated the association between hospital experience with comatose out-of-hospital cardiac arrest (OHCA) patients and important care processes...
  26. doi request reprint Amiodarone, Lidocaine, or Placebo in Out-of-Hospital Cardiac Arrest
    Peter J Kudenchuk
    From the Department of Medicine P J K, T R, G N and Division of Cardiology P J K, University of Washington, the King County Emergency Medical Services, Public Health P J K, T R, The Department of Biostatistics, University of Washington Clinical Trial Center S P B, G N, B L, and University of Washington Harborview Center for Prehospital Emergency Care G N, Seattle, and Clark County Emergency Medical Services, Vancouver L W all in Washington the Department of Emergency Medicine, Oregon Health and Science University, Portland M D Rescu, Li Ka Shing Knowledge Institute, St Michael s Hospital L J M, P D, and the Divisions of Emergency Medicine L J M and Cardiology P D, Department of Medicine, University of Toronto, Toronto, The Department of Emergency Medicine, Ottawa Hospital Research Institute, University of Ottawa, Ottawa C V, I G S, and the Department of Emergency Medicine, Providence Health Care Research Institute, University of British Columbia Faculty of Medicine J C, and Providence Health Care Research Institute and British Columbia Emergency Health Services R S, Vancouver all in Canada University of Pittsburgh, Pittsburgh C W C, A M B National Heart, Hungary
    N Engl J Med 374:1711-22. 2016
    ..Antiarrhythmic drugs are used commonly in out-of-hospital cardiac arrest for shock-refractory ventricular fibrillation or pulseless ventricular tachycardia, but without proven survival benefit...
  27. doi request reprint Patient safety in emergency medical services: a systematic review of the literature
    Blair L Bigham
    Keenan Research Centre, Li Ka Shing Knowledge Institute, St Michael s Hospital, Toronto, Ontario, Canada
    Prehosp Emerg Care 16:20-35. 2012
    ....
  28. ncbi request reprint Measuring the EMS patient access time interval and the impact of responding to high-rise buildings
    Laurie J Morrison
    Prehospital and Transport Medicine Research Program, Sunnybrook and Women s College Health Sciences Center, Toronto, Ontario, Canada
    Prehosp Emerg Care 9:14-8. 2005
    ....
  29. doi request reprint Trial of Continuous or Interrupted Chest Compressions during CPR
    Graham Nichol
    From the University of Washington Harborview Center for Prehospital Emergency Care G N and Clinical Trial Center G N, B L, R H S, S M and Seattle King County Center for Resuscitation Research, University of Washington P K, T D R all in Seattle University of Alabama School of Medicine H W, S S and Birmingham Fire and Rescue Service J R both in Birmingham Pittsburgh Resuscitation Network, University of Pittsburgh, Pittsburgh C W C, J Condle National Heart, Lung, and Blood Institute, Bethesda G S, D E, and Johns Hopkins University School of Medicine, Baltimore M W both in Maryland Ottawa Ontario Prehospital Advanced Life Support Resuscitation Outcomes Consortium, Ottawa Hospital Research Institute, University of Ottawa, Ottawa I S, C V, Li Ka Shing Knowledge Institute, St Michael s Hospital, University of Toronto, Toronto L J M, S C, and the University of British Columbia, Vancouver J Christenson, R S all in Canada the Department of Emergency Medicine, Medical College of Wisconsin, Milwaukee T P A, R C Dallas Fort Worth Center for Resuscitation Research, University of Texas Southwestern Medical Center, Dallas A H I, M I and Virginia Commonwealth University Health System, Richmond J P O
    N Engl J Med 373:2203-14. 2015
    ..We assessed whether outcomes after continuous compressions with positive-pressure ventilation differed from those after compressions that were interrupted for ventilations at a ratio of 30 compressions to two ventilations...
  30. doi request reprint Association of prior β-blocker use and the outcomes of patients with out-of-hospital cardiac arrest
    Andrew Czarnecki
    Schulich Heart Centre, Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada Institute for Clinical Evaluative Sciences ICES, Toronto, Ontario, Canada
    Am Heart J 170:1018-1024.e2. 2015
    ..The main objective of our study was to determine the association between prior β-blocker use and mortality in OHCA patients...
  31. doi request reprint Improving use of targeted temperature management after out-of-hospital cardiac arrest: a stepped wedge cluster randomized controlled trial
    Laurie J Morrison
    1Rescu, Li Ka Shing Knowledge Institute, St Michael s Hospital, Toronto, ON, Canada 2Division of Emergency Medicine, Department of Medicine, University of Toronto, Toronto, ON, Canada 3Institute for Health Policy, Management and Evaluation, University of Toronto, Toronto, ON, Canada 4Department of Emergency Medicine, Faculty of Health Sciences, Queen s University, Kingston, ON, Canada 5Division of Cardiology, Department of Medicine, St Michael s Hospital, University of Toronto, Toronto, ON, Canada 6Division of Pulmonary and Critical Care Medicine and Department of Physical Medicine and Rehabilitation, School of Medicine, Johns Hopkins University, Baltimore, MD 7Interdepartmental Division of Critical Care, Department of Medicine, University of Toronto, Toronto, ON, Canada 8Division of Respirology, Department of Medicine, University Health Network and Mount Sinai Hospital, Toronto, ON, Canada 9Department of Physiology, University of Toronto, Toronto, ON, Canada 10Department of Critical Care Medicine, Sunnybrook Health Sciences Centre, Toronto, ON, Canada 11Department of Emergency Medicine and Critical Care, Lakeridge Health, Oshawa, UK
    Crit Care Med 43:954-64. 2015
    ..International guidelines recommend use of targeted temperature management following resuscitation from out-of-hospital cardiac arrest. This treatment, however, is often neglected or delayed...
  32. ncbi request reprint The impact of distance on triage to trauma center care in an urban trauma system
    Aristithes G Doumouras
    Keenan Research Centre, Li Ka Shing Knowledge Institute, St Michael s Hospital, Division of General Surgery, Department of Surgery, University of Toronto, Toronto, Ontario, Canada
    Prehosp Emerg Care 16:456-62. 2012
    ..In such systems, patients meeting field trauma triage (FTT) criteria should be transported directly to a trauma center, bypassing closer non-trauma centers...
  33. doi request reprint Perceived barriers to therapeutic hypothermia for patients resuscitated from cardiac arrest: a qualitative study of emergency department and critical care workers
    Alina Toma
    Division of Emergency Medicine, Department of Medicine, University of Toronto, Toronto, ON, Canada
    Crit Care Med 38:504-9. 2010
    ..Despite scientific evidence to support therapeutic hypothermia for resuscitated cardiac arrest patients, it is inconsistently and at times inadequately used...
  34. pmc The Toronto prehospital hypertonic resuscitation-head injury and multi organ dysfunction trial (TOPHR HIT)--methods and data collection tools
    Laurie J Morrison
    Rescu, Keenan Research Centre, Li Ka Shing Knowledge Institute, St Michael s Hospital, 30 Bond St, Toronto Ontario, Canada
    Trials 10:105. 2009
    ..We describe a feasibility study of randomizing head injured patients to hypertonic saline and dextran vs. normal saline administration in the out of hospital setting...
  35. ncbi request reprint Derivation of a termination-of-resuscitation guideline for emergency medical technicians using automated external defibrillators
    P Richard Verbeek
    Division of Prehospital Care, Department of Emergency Services, Sunnybrook and Women s College Health Sciences Centre, Toronto, Ontario, Canada
    Acad Emerg Med 9:671-8. 2002
    ....
  36. ncbi request reprint Prehospital transcutaneous cardiac pacing for symptomatic bradycardia or bradyasystolic cardiac arrest: a systematic review
    Jonathan Sherbino
    Division of Emergency Medicine, Department of Medicine, University of Toronto, and Sunnybrook Osler Centre for Prehospital Care, Toronto, Ont, Canada
    Resuscitation 70:193-200. 2006
    ..Many EMS systems are extrapolating these guidelines and employing TCP in the prehospital setting. Our objective was to conduct a systematic review to determine the efficacy of prehospital TCP in the management of these two conditions...
  37. ncbi request reprint Use of personal protective equipment during infectious disease outbreak and nonoutbreak conditions: a survey of emergency medical technicians
    Laura M Visentin
    Dalla Lana School of Public Health, University of Toronto, Toronto, Ont
    CJEM 11:44-56. 2009
    ....
  38. pmc Out-of-hospital cardiac arrest in high-rise buildings: delays to patient care and effect on survival
    Ian R Drennan
    Rescu, Li Ka Shing Knowledge Institute Drennan, Strum, Byers, Buick, Lin, Cheskes, HU, Morrison, St Michael s Hospital, Toronto, Ont Institute of Medical Science, Faculty of Medicine Drennan, Department of Family and Community Medicine Cheskes and Department of Medicine Morrison, University of Toronto, Toronto, Ont Sunnybrook Centre for Prehospital Medicine Drennan, Buick, Cheskes, Sunnybrook Health Sciences Centre, Toronto, Ont
    CMAJ 188:413-9. 2016
    ..We examined the relation between floor of patient contact and survival after cardiac arrest in residential buildings...
  39. doi request reprint The association of maximum Troponin values post out-of-hospital cardiac arrest with electrocardiographic findings, cardiac reperfusion procedures and survival to discharge; A Sub-study of ROC PRIMED
    Laurie J Morrison
    Rescu, Li Ka Shing Knowledge Institute, St Michael s Hospital, Division of Emergency Medicine, Department of Medicine, University of Toronto, 30 Bond St, Toronto Ontario M5B 1W8, Canada Electronic address
    Resuscitation . 2016
    ..The role of Troponin (Tn) levels in the management of patients post out-of-hospital cardiac arrest (OHCA) is unclear...
  40. doi request reprint Targeted temperature management processes and outcomes after out-of-hospital cardiac arrest: an observational cohort study*
    Steve Lin
    1Rescu, Li Ka Shing Knowledge Institute of St Michael s Hospital, Toronto, ON, Canada 2Division of Emergency Medicine, Department of Medicine, University of Toronto, Toronto, ON, Canada 3Institute for Clinical Evaluative Sciences, Sunnybrook Research Institute, Toronto, ON, Canada 4Interdepartmental Division of Critical Care, Department of Medicine, University of Toronto, Toronto, ON, Canada 5Department of Critical Care Medicine, Sunnybrook Health Sciences Centre, Toronto, ON, Canada 6Division of Cardiology, Department of Medicine, University of Toronto, Toronto, ON, Canada 7Department of Emergency Medicine, Queen s University, Kingston, ON, Canada
    Crit Care Med 42:2565-74. 2014
    ..The objective of this study was to evaluate these processes of care with survival and neurological function in patients after out-of-hospital cardiac arrest...
  41. pmc What is the role of chest compression depth during out-of-hospital cardiac arrest resuscitation?
    Ian G Stiell
    Department of Emergency Medicine and Ottawa Hospital Research Institute, University of Ottawa, Ottawa, Ontario, Canada
    Crit Care Med 40:1192-8. 2012
    ..We sought to study patterns of cardiopulmonary resuscitation compression depth and their associations with patient outcomes in out-of-hospital cardiac arrest cases treated by the 2005 guideline standards...
  42. pmc Out-of-hospital cardiac arrests occurring in southern Ontario health care clinics: bystander cardiopulmonary resuscitation and automated external defibrillator use
    Steven C Brooks
    Rescu, St Michael s Hospital, 30 Bond St, Toronto, ON M5B 1W8, Canada
    Can Fam Physician 56:e213-8. 2010
    ....
  43. pmc Out-of-hospital cardiac arrest frequency and survival: evidence for temporal variability
    Steven C Brooks
    Rescu, Keenan Research Centre, Li Ka Shing Knowledge Institute, St Michael s Hospital Division of Emergency Medicine, Department of Medicine, University of Toronto, Toronto, Ontario, Canada
    Resuscitation 81:175-81. 2010
    ..Some cardiac phenomena demonstrate temporal variability. We evaluated temporal variability in out-of-hospital cardiac arrest (OHCA) frequency and outcome...
  44. ncbi request reprint Prehospital 12-lead electrocardiography impact on acute myocardial infarction treatment times and mortality: a systematic review
    Laurie J Morrison
    Department of Emergency Services, Sunnybrook and Women s College Health Sciences Center, Toronto, Canada
    Acad Emerg Med 13:84-9. 2006
    ..The authors systematically reviewed the literature to report whether mortality or treatment time intervals improved when compared with standard care...
  45. ncbi request reprint Responses to written notification during out-of-hospital care trials using waiver of informed consent
    Julia M Spence
    Centre for Research on Inner City Health, Department of Emergency Medicine, St Michael s Hospital, Toronto, Ontario, Canada
    Acad Emerg Med 12:1099-103. 2005
    ..Resuscitation research has been allowed to proceed using waiver of consent when compliance with guidelines is assured. In these circumstances, institutional review boards (IRBs) may request notification of enrolled patients...
  46. doi request reprint Development of a data dictionary for the Strategies for Post Arrest Resuscitation Care (SPARC) network for post cardiac arrest research
    Steve Lin
    Division of Emergency Medicine, Department of Medicine, University of Toronto, Toronto, Ontario, Canada
    Resuscitation 82:419-22. 2011
    ..However, collection of many of these variables poses significant practical challenges. In addition, several important variables in post resuscitation research are missing...
  47. doi request reprint Abnormal coagulation tests are associated with progression of traumatic intracranial hemorrhage
    Christopher B Allard
    Department of Surgery and or Critical Care Medicine, Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada
    J Trauma 67:959-67. 2009
    ..ICH commonly increases in size and coagulopathy has been implicated in such progression. We investigated the association between coagulopathy diagnosed by routine laboratory tests and ICH progression...
  48. doi request reprint Does location matter? A proposed methodology to evaluate neighbourhood effects on cardiac arrest survival and bystander CPR
    Jason E Buick
    Rescu, Li Ka Shing Knowledge Institute, St Michael s Hospital, Toronto, ON
    CJEM 17:286-94. 2015
    ..Yet, this approach has rarely been used for OHCA. This work outlines a methodology to investigate multiple neighbourhood factors as determinants of OHCA outcomes...
  49. pmc Effect of gender on outcome of out of hospital cardiac arrest in the Resuscitation Outcomes Consortium
    Laurie J Morrison
    Rescu, Li Ka Shing Knowledge Institute, St Michael s Hospital, University of Toronto, Toronto, ON, Canada Division of Emergency Medicine Department of Medicine, University of Toronto, Toronto, ON, Canada Institute of Health Policy, Management and Evaluation, University of Toronto, Toronto, ON, Canada Electronic address
    Resuscitation 100:76-81. 2016
    ..This study examined the relationship between gender and outcomes of non-traumatic out-of-hospital cardiac arrest (OHCA)...
  50. doi request reprint The association between manual mode defibrillation, pre-shock pause duration and appropriate shock delivery when employed by basic life support paramedics during out-of-hospital cardiac arrest
    Sheldon Cheskes
    Sunnybrook Centre for Prehospital Medicine, Toronto, ON, Canada University of Toronto, Department of Family and Community Medicine, Division of Emergency Medicine, Toronto, ON, Canada Rescu Li Ka Shing Knowledge Institute, St Michaels Hospital, Toronto, ON, Canada Electronic address
    Resuscitation 90:61-6. 2015
    ....
  51. doi request reprint Trends in short- and long-term survival among out-of-hospital cardiac arrest patients alive at hospital arrival
    Michael K Y Wong
    From the Institute of Clinical Evaluative Sciences, Toronto, Ontario, Canada M K Y W, F Q, P C A, D C S, J V T, H C W, D T K Department of Medicine, University of Toronto, Toronto, Ontario, Canada M K Y W, L J M, S C, P D, D C S, J V T, P R V, H C W, D T K Li Ka Shing Knowledge Institute, St Michael s Hospital, Toronto, Ontario, Canada L J M, S C, P D, P R V Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada S C, D C S, J V T, P R V Schulich Heart Centre, Toronto, Ontario, Canada H C W, Toulouse
    Circulation 130:1883-90. 2014
    ..Out-of-hospital cardiac arrest (OHCA) is associated with a poor prognosis and poses a significant burden to the healthcare system, but few studies have evaluated whether OHCA incidence and survival have changed over time...
  52. doi request reprint The Society for Obstetric Anesthesia and Perinatology consensus statement on the management of cardiac arrest in pregnancy
    Steven Lipman
    From the Department of Anesthesia, Stanford University School of Medicine, Stanford, California Surgical Intensive Care Unit, Shaare Zedek Medical Centre, Jerusalem, Israel Department of Cardiology, University of Toronto, Toronto, Canada Department of Anesthesiology, University of Arkansas for Medical Sciences, Little Rock, Arkansas Rescu, Li Ka Shing Knowledge Institute, St Michael s Hospital, Division of Emergency Medicine, Department of Medicine, University of Toronto, Toronto Ontario Canada Department of Obstetrics and Gynecology, Oregon Health and Science University, Springfield, Oregon Department of Anesthesiology, Perioperative and Pain Medicine, Brigham and Women s Hospital, Boston, Massachusetts Department of Obstetrics and Gynecology, Stanford University School of Medicine Division of Neonatal and Developmental Medicine, Department of Pediatrics, Stanford University, Stanford, California Department of Anesthesiology, Baylor College of Medicine, Houston, Texas Center for Advanced Pediatric and Perinatal Education, Lucile Packard Children s Hospital at Stanford University, Stanford Santa Barbara Cottage Hospital, Santa Barbara, California and Department of Anesthesia, University of Toronto, Toronto, Canada
    Anesth Analg 118:1003-16. 2014
    ..This statement also expands on, interprets, and discusses controversial aspects of material covered in the American Heart Association 2010 guidelines. ..
  53. doi request reprint Implementation trial of the basic life support termination of resuscitation rule: reducing the transport of futile out-of-hospital cardiac arrests
    Laurie J Morrison
    Rescu, Keenan Research Centre, Li Ka Shing Knowledge Institute at St Michael s Hospital, University of Toronto, Toronto, Ontario, Canada Division of Emergency, Department of Medicine, University of Toronto, Toronto, Ontario, Canada Institute of Health Policy, Management and Evaluation, University of Toronto, Toronto, Ontario, Canada Electronic address
    Resuscitation 85:486-91. 2014
    ....
  54. doi request reprint Identifying locations for public access defibrillators using mathematical optimization
    Timothy C Y Chan
    Department of Mechanical and Industrial Engineering, University of Toronto, Toronto, ON, Canada
    Circulation 127:1801-9. 2013
    ..Our objective was to develop such a method and test its performance against a population-guided approach...
  55. pmc A knowledge translation collaborative to improve the use of therapeutic hypothermia in post-cardiac arrest patients: protocol for a stepped wedge randomized trial
    Katie N Dainty
    RESCU Research Program, Keenan Research Centre, Li Ka Shing Knowledge Institute, St, Michael s Hospital Toronto, Canada
    Implement Sci 6:4. 2011
    ..Despite the strong evidence for its efficacy and the apparent simplicity of this intervention, recent surveys show that therapeutic hypothermia is delivered inconsistently, incompletely, and often with delay...
  56. pmc Emergency department overcrowding and ambulance transport delays for patients with chest pain
    Michael J Schull
    Department of Emergency Services, Toronto, ON, Canada
    CMAJ 168:277-83. 2003
    ..Emergency department overcrowding sometimes results in diversion of ambulances to other locations. We sought to determine the resulting prehospital delays for cardiac patients...
  57. ncbi request reprint Evaluating paramedic comfort with field pronouncement: development and validation of an outcome measure
    Laurie J Morrison
    Department of Emergency Services, Sunnybrook and Women s Health Sciences Center, Division of Emergency Medicine, Department of Medicine, University of Toronto, Ontario, Canada
    Acad Emerg Med 10:633-7. 2003
    ..The authors developed and evaluated the reliability and validity of a survey instrument measuring paramedic comfort with field pronouncement...
  58. doi request reprint Implementation of therapeutic hypothermia guidelines for post-cardiac arrest syndrome at a glacial pace: seeking guidance from the knowledge translation literature
    Steven C Brooks
    Division of Emergency Medicine, Department of Medicine, University of Toronto, Canada
    Resuscitation 77:286-92. 2008
    ..We will review the underlying phenomenon of research implementation into practice, specific barriers to guideline implementation and interventions that may improve therapeutic hypothermia uptake...
  59. ncbi request reprint The Postcardiac Arrest Consult Team: Impact on Hospital Care Processes for Out-of-Hospital Cardiac Arrest Patients
    Steven C Brooks
    1Department of Emergency Medicine, Queen s University, Kingston, ON, Canada 2Rescu, Li Ka Shing Knowledge Institute, St Michael s Hospital, Toronto, Ontario Canada 3Department of Critical Care Medicine, Sunnybrook Health Sciences Centre, Toronto, ON, Canada 4Interdepartmental Division of Critical Care Medicine, University of Toronto, Toronto, ON, Canada 5Institute of Health Policy, Management and Evaluation, University of Toronto, Toronto, ON 6Critical Care Department, St Michael s Hospital, Toronto, ON, Canada 7Department of Emergency Medicine, St Michael s Hospital, Toronto, ON, Canada 8Division of Emergency Medicine, Department of Medicine, University of Toronto, Toronto, ON, Canada 9Heart and Vascular Program, St Michael s Hospital, Toronto, ON, Canada 10Division of Cardiology, Department of Medicine, University of Toronto, Toronto, ON, Canada 11Department of Anesthesia, St Michael s Hospital, Toronto, ON, Canada 12Division of Cardiology, Imperial College London
    Crit Care Med 44:2037-2044. 2016
    ..To evaluate whether a Post-Arrest Consult Team improved care and outcomes for patients with out-of-hospital cardiac arrest...
  60. doi request reprint The association between neighborhood effects and out-of-hospital cardiac arrest outcomes
    Jason E Buick
    Rescu, Li Ka Shing Knowledge Institute, St Michael s Hospital, Toronto, Canada Institute of Health Policy, Management and Evaluation, Faculty of Medicine, University of Toronto, Toronto, Canada Electronic address
    Resuscitation 103:14-9. 2016
    ..Whether neighborhood factors further influence a return of spontaneous circulation or survival after OHCA is poorly understood...
  61. doi request reprint The association between chest compression release velocity and outcomes from out-of-hospital cardiac arrest
    Sheldon Cheskes
    Sunnybrook Centre for Prehospital Medicine, Toronto, ON, Canada University of Toronto, Department of Family and Community Medicine, Division of Emergency Medicine, Toronto, ON, Canada Rescu, Li Ka Shing Knowledge Institute, St Michaels Hospital, Toronto, ON, Canada Electronic address
    Resuscitation 86:38-43. 2015
    ..Recently, it has been suggested that a new metric, chest compression release velocity (CCRV), may be associated with improved survival from OHCA...
  62. doi request reprint Adrenaline for out-of-hospital cardiac arrest resuscitation: a systematic review and meta-analysis of randomized controlled trials
    Steve Lin
    Rescu, Li Ka Shing Knowledge Institute of St Michael s Hospital, Toronto, Ontario, Canada Division of Emergency Medicine, Department of Medicine, University of Toronto, Toronto, Ontario, Canada Electronic address
    Resuscitation 85:732-40. 2014
    ..The evidence for adrenaline in out-of-hospital cardiac arrest (OHCA) resuscitation is inconclusive. We systematically reviewed the efficacy of adrenaline for adult OHCA...
  63. ncbi request reprint Patient safety in emergency medical services: executive summary and recommendations from the Niagara Summit
    Blair L Bigham
    University of Toronto, Toronto, Canada
    CJEM 13:13-8. 2011
    ....
  64. doi request reprint Management of cardiac arrest in pregnancy: a systematic review
    Farida M Jeejeebhoy
    Department of Medicine, University of Toronto, Division of Cardiology, Mount Sinai Hospital, Toronto, ON, Canada
    Resuscitation 82:801-9. 2011
    ..To describe the consensus on science pertaining to resuscitation of the pregnant patient...
  65. doi request reprint Survival rates in out-of-hospital cardiac arrest patients transported without prehospital return of spontaneous circulation: an observational cohort study
    Ian R Drennan
    Rescu, Li Ka Shing Knowledge Institute, St Michael s Hospital, Toronto, Canada Institute of Medical Science, Department of Medicine, University of Toronto, Toronto, Canada York Region Emergency Medical Services, Ontario, Canada Electronic address
    Resuscitation 85:1488-93. 2014
    ....
  66. pmc Expanding Paramedicine in the Community (EPIC): study protocol for a randomized controlled trial
    Ian R Drennan
    Rescu, Li Ka Shing Knowledge Institute, St, Michael s Hospital, 30 Bond St, Toronto, ON M5B 1W8, Canada
    Trials 15:473. 2014
    ..Expanding the paramedic's scope of practice to include community-based care may decrease the utilization of acute care and hospital-based health care resources by patients with chronic disease...
  67. doi request reprint Compressions during defibrillator charging shortens shock pause duration and improves chest compression fraction during shockable out of hospital cardiac arrest
    Sheldon Cheskes
    Sunnybrook Centre for Prehospital Medicine, Toronto, ON, Canada University of Toronto, Division of Emergency Medicine, Toronto, ON, Canada Rescu Li Ka Shing Knowledge Institute, St Michaels Hospital, Toronto, ON, Canada Electronic address
    Resuscitation 85:1007-11. 2014
    ..Compressions during defibrillator charging (CDC) has been proposed as a technique to shorten shock pause duration...
  68. doi request reprint Mechanical versus manual chest compressions for cardiac arrest
    Steven C Brooks
    Department of Emergency Medicine, Queen s University, Kingston General Hospital, 76 Stuart Street, Empire 3, Kingston, Ontario, Canada, K7L 2V7
    Cochrane Database Syst Rev 2:CD007260. 2014
    ..Mechanical chest compression devices have been proposed to improve the effectiveness of cardiopulmonary resuscitation (CPR)...
  69. ncbi request reprint Predictive validity of the Global Assessment Form used in a final-year undergraduate rotation in emergency medicine
    Glen W Bandiera
    Department of Emergency Services, St Michael s Hospital, Toronto, Ontario, Canada
    Acad Emerg Med 9:889-95. 2002
    ....
  70. ncbi request reprint Mechanical versus manual chest compressions for cardiac arrest
    Steven C Brooks
    Rescu, Keenan Research Centre, Li Ka Shing Knowledge Institute at St Michael s Hospital and the Sunnybrook Health Sciences Centre Program for Trauma, Emergency and Critical Care, Division of Emergency Medicine, Department of Medicine, University of Toronto, St Michael s Hospital, 30 Bond Street, Toronto, Ontario, Canada, M5B 1W8
    Cochrane Database Syst Rev 1:CD007260. 2011
    ..Mechanical chest compression devices have been proposed to improve the effectiveness of cardiopulmonary resuscitation (CPR)...
  71. pmc Immediate angioplasty after thrombolysis: a systematic review
    Warren J Cantor
    Division of Cardiology, St Michael s Hospital, and the Department of Medicine, University of Toronto, Toronto, Ontario, Canada
    CMAJ 173:1473-81. 2005
    ..We performed a systematic review of the related literature to determine whether thrombolysis followed by transfer for immediate or early PCI is safe, feasible and superior to conservative management...
  72. doi request reprint The effect of time to defibrillation and targeted temperature management on functional survival after out-of-hospital cardiac arrest
    Ian R Drennan
    Rescu, Li Ka Shing Knowledge Institute, St Michael s Hospital, University of Toronto, Toronto, ON, Canada Institute of Medical Science, Department of Medicine, University of Toronto, Toronto, ON, Canada School of Health and Wellness, Georgian College, Barrie, ON, Canada Electronic address
    Resuscitation 85:1623-8. 2014
    ..Furthermore, the effect of post-cardiac arrest targeted temperature management (TTM) on functional survival during each phase is unknown...
  73. doi request reprint Impact of a formal mentoring program on academic promotion of Department of Medicine faculty: a comparative study
    Laurie J Morrison
    St Michael s Hospital, Canada
    Med Teach 36:608-14. 2014
    ..To evaluate the impact of a formal mentoring program on time to academic promotion and differences in gender-based outcomes...
  74. doi request reprint Expanding paramedic scope of practice in the community: a systematic review of the literature
    Blair L Bigham
    Keenan Research Centre, Li Ka Shing Knowledge Institute, St Michael s Hospital, 30 Bond Street, Toronto, Ontario, Canada M5B 1W8
    Prehosp Emerg Care 17:361-72. 2013
    ..Utilizing paramedics for the management of urgent, low-acuity illnesses and injuries has been coined "community paramedicine," but the role, safety, and effectiveness of this concept are poorly understood...
  75. ncbi request reprint Defining the outcome measures for out-of-hospital trials in acute pulmonary edema
    Michelle Welsford
    Research Program, Division of Prehospital Care, Department of Emergency Services, Sunnybrook and Women s College Health Sciences Centre, Toronto, Ontario, Canada
    Acad Emerg Med 9:983-8. 2002
    ..The objective of this study was to define a set of clinically relevant outcome measures for future out-of-hospital trials in APE...
  76. doi request reprint Resuscitation with hypertonic saline-dextran reduces serum biomarker levels and correlates with outcome in severe traumatic brain injury patients
    Andrew J Baker
    Brain Injury Laboratory, Cara Phelan Centre for Trauma Research, St Michael s Hospital, University of Toronto, Toronto, Ontario, Canada
    J Neurotrauma 26:1227-40. 2009
    ..Pre-hospital resuscitation with HSD is associated with a reduction in serum S100B, NSE, and MBP concentrations, which are correlated with better outcome after severe TBI...
  77. pmc The Resuscitation Outcomes Consortium Epistry-Trauma: design, development, and implementation of a North American epidemiologic prehospital trauma registry
    Craig D Newgard
    Center for Policy and Research in Emergency Medicine, Department of Emergency Medicine, Oregon Health and Science University, Portland, OR 97239 3098, United States
    Resuscitation 78:170-8. 2008
    ..This data registry samples patients from 264 EMS agencies transporting to 287 acute care hospitals in both the United States and Canada...
  78. ncbi request reprint Subcutaneous glucagon may be better than oral glucose for prehospital treatment of symptomatic hypoglycemia
    Marian J Vermeulen
    Diabetes Care 26:2472-3. 2003
  79. ncbi request reprint Recommended guidelines for monitoring, reporting, and conducting research on medical emergency team, outreach, and rapid response systems: an Utstein-style scientific statement. A Scientific Statement from the International Liaison Committee on Resuscitat
    Mary Ann Peberdy
    Resuscitation 75:412-33. 2007
  80. doi request reprint Hypertonic resuscitation: design and implementation of a prehospital intervention trial
    Karen J Brasel
    Department of Surgery, Division of Trauma Critical Care, Medical College of Wisconsin, Milwaukee, WI 53226, USA
    J Am Coll Surg 206:220-32. 2008
    ..Trauma is the leading cause of death among North Americans between the ages of 1 and 44 years. Resuscitation with hypertonic saline (7.5%) solutions can reduce mortality in hypotensive and brain-injured patients...
  81. pmc Transfer for urgent percutaneous coronary intervention early after thrombolysis for ST-elevation myocardial infarction: the TRANSFER-AMI pilot feasibility study
    Warren J Cantor
    Southlake Regional Health Centre, Newmarket, Canada
    Can J Cardiol 22:1121-6. 2006
    ..Urgent PCI after thrombolysis may optimize reperfusion and prevent reinfarction and recurrent ischemia...
  82. ncbi request reprint Scientific knowledge gaps and clinical research priorities for cardiopulmonary resuscitation and emergency cardiovascular care identified during the 2005 International Consensus Conference on ECC [corrected] and CPR science with treatment recommendations:
    Raúl J Gazmuri
    North Chicago VA and Rosalind Franklin University of Medicine and Science, USA
    Circulation 116:2501-12. 2007
  83. ncbi request reprint Scientific knowledge gaps and clinical research priorities for cardiopulmonary resuscitation and emergency cardiovascular care identified during the 2005 International Consensus Conference on ECC and CPR Science with Treatment Recommendations. A consensus
    Raúl J Gazmuri
    Rosalind Franklin University of Medicine and Science, North Chicago Medical Center, Chicago, USA
    Resuscitation 75:400-11. 2007
  84. ncbi request reprint Recommended guidelines for monitoring, reporting, and conducting research on medical emergency team, outreach, and rapid response systems: an Utstein-style scientific statement: a scientific statement from the International Liaison Committee on Resuscitat
    Mary Ann Peberdy
    Virginia Commonwealth University, USA
    Circulation 116:2481-500. 2007