St. Michael's Hospital

Summary

Organization: St. Michael's Hospital
Country: Canada

Top Publications

  1. doi Laparoscopic gastric surgery in an enhanced recovery programme
    T P Grantcharov
    Division of General Surgery, St Michael s Hospital, University of Toronto, Toronto, Ontario, Canada
    Br J Surg 97:1547-51. 2010
  2. ncbi Practice patterns of pulmonologists and family physicians for occupational asthma
    D Linn Holness
    Gage Occupational and Environmental Health Unit, St Michael s Hospital, University of Toronto, ON, Canada M5B 1W8
    Chest 132:1526-31. 2007
  3. ncbi Daily variation in endotoxin levels is associated with increased organ failure in critically ill patients
    David J Klein
    St Michael s Hospital, University of Toronto, Ontario, Canada
    Shock 28:524-9. 2007
  4. ncbi Severe hemodilutional anemia increases cerebral tissue injury following acute neurotrauma
    Gregory M T Hare
    Department of Anesthesia, University of Toronto, St Michael s Hospital, 30 Bond St, Toronto, Ontario M5B 1W8, Canada
    J Appl Physiol (1985) 103:1021-9. 2007
  5. pmc Postoperative irradiation for rectal cancer increases the risk of small bowel obstruction after surgery
    Nancy N Baxter
    Department of Surgery, St Michael s Hospital, University of Toronto, Toronto, Ontario, Canada
    Ann Surg 245:553-9. 2007
  6. ncbi Increased cerebral and renal endothelial nitric oxide synthase gene expression after cardiopulmonary bypass in the rat
    C David Mazer
    Department of Anesthesia, University of Toronto, St Michael s Hospital, Seneca College, Toronto, Ontario, Canada
    J Thorac Cardiovasc Surg 133:13-20. 2007
  7. pmc Anemia, transfusion, and phlebotomy practices in critically ill patients with prolonged ICU length of stay: a cohort study
    Clarence Chant
    Leslie Dan Faculty of Pharmacy, University of Toronto, 144 College Street, Toronto, Ontario, Canada M5S 3M2
    Crit Care 10:R140. 2006
  8. ncbi Beta2 adrenergic antagonist inhibits cerebral cortical oxygen delivery after severe haemodilution in rats
    G M T Hare
    Department of Anaesthesia and the Cara Phelan Centre for Trauma Research, University of Toronto, St Michael s Hospital 30 Bond Street, Toronto, Ontario M5B 1W8, Canada
    Br J Anaesth 97:617-23. 2006
  9. ncbi Reliability and validity of the body image after breast cancer questionnaire
    Nancy N Baxter
    Department of Surgery, University of Toronto, Canada
    Breast J 12:221-32. 2006
  10. ncbi Malignant paraganglioma of the urinary bladder: Immunohistochemical study of prognostic indicators
    Kalman Kovacs
    Department of Laboratory Medicine, St Michael s Hospital, University of Toronto, Toronto, Ontario, Canada
    Endocr Pathol 16:363-9. 2005

Research Grants

  1. Health care utilitzation in homeless people
    Stephen Hwang; Fiscal Year: 2005
  2. PATHOPHYSIOLOGY OF CHRONIC CEREBRAL VASOSPASM
    Robert MacDonald; Fiscal Year: 2000
  3. PATHOPHYSIOLOGY OF CHRONIC CEREBRAL VASOSPASM
    Robert MacDonald; Fiscal Year: 2005

Detail Information

Publications62

  1. doi Laparoscopic gastric surgery in an enhanced recovery programme
    T P Grantcharov
    Division of General Surgery, St Michael s Hospital, University of Toronto, Toronto, Ontario, Canada
    Br J Surg 97:1547-51. 2010
    ..The effects of a combination of laparoscopic resection and accelerated recovery have not been examined previously in the context of gastric surgery...
  2. ncbi Practice patterns of pulmonologists and family physicians for occupational asthma
    D Linn Holness
    Gage Occupational and Environmental Health Unit, St Michael s Hospital, University of Toronto, ON, Canada M5B 1W8
    Chest 132:1526-31. 2007
    ..Our objective was to document and compare the practice patterns, barriers, and needs for early diagnosis of OA among pulmonologists and family physicians...
  3. ncbi Daily variation in endotoxin levels is associated with increased organ failure in critically ill patients
    David J Klein
    St Michael s Hospital, University of Toronto, Ontario, Canada
    Shock 28:524-9. 2007
    ..Further studies are warranted to assess the role of daily variation in endotoxin levels in the pathogenesis and potential therapy of organ failure in the critically ill...
  4. ncbi Severe hemodilutional anemia increases cerebral tissue injury following acute neurotrauma
    Gregory M T Hare
    Department of Anesthesia, University of Toronto, St Michael s Hospital, 30 Bond St, Toronto, Ontario M5B 1W8, Canada
    J Appl Physiol (1985) 103:1021-9. 2007
    ..05 for both). Hemodilutional anemia reduced cerebral Pbr(O(2)) and oxygen extraction and increased cell death following TBI. These results support our hypothesis that acute anemia accentuated hypoxic cerebral injury after neurotrauma...
  5. pmc Postoperative irradiation for rectal cancer increases the risk of small bowel obstruction after surgery
    Nancy N Baxter
    Department of Surgery, St Michael s Hospital, University of Toronto, Toronto, Ontario, Canada
    Ann Surg 245:553-9. 2007
    ..To determine the risk of small bowel obstruction (SBO) after irradiation (RT) for rectal cancer..
  6. ncbi Increased cerebral and renal endothelial nitric oxide synthase gene expression after cardiopulmonary bypass in the rat
    C David Mazer
    Department of Anesthesia, University of Toronto, St Michael s Hospital, Seneca College, Toronto, Ontario, Canada
    J Thorac Cardiovasc Surg 133:13-20. 2007
    ..This study tested the hypothesis that cardiopulmonary bypass and anemia stimulate an increase in cerebral and renal endothelial nitric oxide synthase gene expression in an experimental model of cardiopulmonary bypass...
  7. pmc Anemia, transfusion, and phlebotomy practices in critically ill patients with prolonged ICU length of stay: a cohort study
    Clarence Chant
    Leslie Dan Faculty of Pharmacy, University of Toronto, 144 College Street, Toronto, Ontario, Canada M5S 3M2
    Crit Care 10:R140. 2006
    ..This study was performed to characterize anemia, transfusion, and phlebotomy practices in patients with prolonged ICU LOS...
  8. ncbi Beta2 adrenergic antagonist inhibits cerebral cortical oxygen delivery after severe haemodilution in rats
    G M T Hare
    Department of Anaesthesia and the Cara Phelan Centre for Trauma Research, University of Toronto, St Michael s Hospital 30 Bond Street, Toronto, Ontario M5B 1W8, Canada
    Br J Anaesth 97:617-23. 2006
    ..This study tests the hypothesis that inhibition of cerebral vasodilatation by systemic beta2 adrenergic blockade would impair cerebral oxygen delivery leading to tissue hypoxia in severely haemodiluted rats...
  9. ncbi Reliability and validity of the body image after breast cancer questionnaire
    Nancy N Baxter
    Department of Surgery, University of Toronto, Canada
    Breast J 12:221-32. 2006
    ..The BIBCQ provides a reliable and valid assessment of the long-term impact of breast cancer on body image. It is suitable for use in research focusing on this issue...
  10. ncbi Malignant paraganglioma of the urinary bladder: Immunohistochemical study of prognostic indicators
    Kalman Kovacs
    Department of Laboratory Medicine, St Michael s Hospital, University of Toronto, Toronto, Ontario, Canada
    Endocr Pathol 16:363-9. 2005
    ..Abnormalities in vascular architecture and marked expression of VEGF in the tumor cells may be regarded as prognostic signs to predict the formation of metastases...
  11. ncbi Diagnosis of coronary artery disease in the diabetic patient
    Lawrence A Leiter
    Division of Endocrinology, St Michael s Hospital, University of Toronto, Toronto, Ontario
    Can J Cardiol 22:7A-8A. 2006
  12. ncbi A memoir of a sojourn as editor of The Canadian Journal of Psychiatry
    Edward Kingstone
    St Michael s Hospital, Toronto, Ontario
    Can J Psychiatry 50:671-4. 2005
  13. ncbi Responses to written notification during out-of-hospital care trials using waiver of informed consent
    Julia M Spence
    Centre for Research on Inner City Health, Department of Emergency Medicine, St Michael s Hospital, Toronto, Ontario, Canada
    Acad Emerg Med 12:1099-103. 2005
    ..Resuscitation research has been allowed to proceed using waiver of consent when compliance with guidelines is assured. In these circumstances, institutional review boards (IRBs) may request notification of enrolled patients...
  14. ncbi Failure of enoxaparin during coronary stenting: a case report
    Robert J Chisholm
    Division of Cardiology, St Michael s Hospital, University of Toronto, Toronto, Canada
    Catheter Cardiovasc Interv 66:343-5. 2005
    ..Low-molecular-weight heparin in the absence of a glycoprotein IIb/IIIa receptor blocker may be insufficient during percutaneous coronary intervention...
  15. ncbi Diagnosis and treatment of Paget's disease of bone
    Robert G Josse
    Division of Endocrinology and Metabolism, Department of Medicine, St Michael s Hospital, University of Toronto, Toronto, Ontario
    Clin Invest Med 30:E210-23. 2007
    ..The Panel recommends treating PDB with bisphosphonates that have demonstrated superior efficacy and remission rates...
  16. ncbi Providing an in-centre nocturnal hemodialysis program: the pearls and pitfalls
    Alison Thomas
    Michael s Hospital, Toronto, ON
    CANNT J 17:39-41. 2007
    ..This article will outline both the successes and challenges of this unique approach to hemodialysis...
  17. doi Combined single-stage osseous and soft tissue reconstruction of the tibia with the Ilizarov method and tissue transfer
    Michael D McKee
    Division of Orthopaedics, St Michael s Hospital and the University of Toronto, Toronto, Ontario, Canada
    J Orthop Trauma 22:183-9. 2008
    ..To determine the outcome of single-stage soft tissue and osseous reconstruction using the Ilizarov method and soft-tissue transfer...
  18. pmc Adenohypophysitis in rat pituitary allografts
    Fabio Rotondo
    Department of Laboratory Medicine, Division of Pathology, St Michael s Hospital, University of Toronto, Toronto, ON, Canada
    Int J Exp Pathol 91:445-50. 2010
    ....
  19. doi Adoptive-transfer effects of intravenous immunoglobulin in autoimmunity
    Alan H Lazarus
    The Canadian Blood Services, Ottawa, ON, Canada
    J Clin Immunol 30:S20-3. 2010
    ..This review will highlight recent work in murine systems that indicates that the effects of IVIG can be adoptively transferred in some autoimmune diseases and inflammatory states...
  20. pmc Knowledge translation in emergency medical services: a qualitative survey of barriers to guideline implementation
    Blair L Bigham
    Rescu, Keenan Research Centre, Li Ka Shing Knowledge Institute, St Michael s Hospital, University of Toronto, Toronto, Canada
    Resuscitation 81:836-40. 2010
    ..The American Heart Association (AHA) released guidelines to improve survival rates from out-of-hospital cardiac arrest in 2005. We sought to identify what barriers delayed the implementation of these guidelines in EMS agencies...
  21. pmc Evaluation of pneumonia severity and acute physiology scores to predict ICU admission and mortality in patients hospitalized for influenza
    Matthew P Muller
    Department of Medicine, St Michael s Hospital, University of Toronto, Toronto, Canada
    PLoS ONE 5:e9563. 2010
    ..The demand for inpatient medical services increases during influenza season. A scoring system capable of identifying influenza patients at low risk death or ICU admission could help clinicians make hospital admission decisions...
  22. pmc Patterns of urban violent injury: a spatio-temporal analysis
    Michael Cusimano
    Injury Prevention Research Office, St Michael s Hospital, Toronto, Canada
    PLoS ONE 5:e8669. 2010
    ..The purpose of this study was to describe the combined spatial and temporal characteristics of violent injury in a large urban centre...
  23. doi Shock wave lithotripsy: a randomized, double-blind trial to compare immediate versus delayed voltage escalation
    R John D A Honey
    Department of Urology, St Michael s Hospital, Toronto, Ontario, Canada
    Urology 75:38-43. 2010
    ..Preliminary data have suggested that delaying voltage escalation for SWL might both improve fragmentation and minimize renal injury...
  24. doi Building knowledge for safer care: nursing research advancing practice
    Lianne Jeffs
    Keenan Research Centre, Li Ka Shing Knowledge Institute, Toronto, Ontario, Canada
    J Nurs Care Qual 24:257-62. 2009
    ..Participating nurses evolved from research novices to key champions in advancing nursing practice, patient safety, and quality improvement...
  25. doi The adherence support gap: the 'ideal' versus 'reality' of antiretroviral adherence support provided by HIV health providers in clinical practice
    Laura Y Park-Wyllie
    Li Ka Shing Knowledge Institute, St Michael s Hospital, Toronto, ON, Canada
    Ann Pharmacother 43:1036-44. 2009
    ....
  26. doi A mathematical model for predicting ultrasonic measurement of total knee replacement contact areas
    Rad Zdero
    Martin Orthopaedic Biomechanics Laboratory, St Michael s Hospital, Toronto, ON M5B 1W8, Canada
    IEEE Trans Biomed Eng 56:565-71. 2009
    ..This investigation was part of an ongoing project to develop an engineering design tool for measuring surface contact areas at the tibio-femoral interfaces of clinically employed TKR prostheses...
  27. ncbi A biomechanical assessment of the coupling of torsion and tension in the human scapholunate ligament
    R Zdero
    Martin Orthopaedic Biomechanics Laboratory, St Michael s Hospital, Toronto, ON, Canada
    Proc Inst Mech Eng H 222:907-14. 2008
    ..This may suggest interplay between these two parameters in the stabilization of the ligament during normal motion and for injury cascades...
  28. ncbi Clazosentan: an endothelin receptor antagonist for treatment of vasospasm after subarachnoid hemorrhage
    R Loch MacDonald
    University of Toronto, St Michael Hospital, Division of Neurosurgery, Keenan Research Centre, Toronto, Ontario, Canada
    Expert Opin Investig Drugs 17:1761-7. 2008
    ..All patients will undergo neurosurgical aneurysm clipping and outcome will be assessed primarily based on mortality and vasospasm-related morbidity...
  29. doi Orthopaedic surgery in haemophilia patients with inhibitors: a practical guide to haemostatic, surgical and rehabilitative care
    J M Teitel
    Department of Medicine, St Michael s Hospital and University of Toronto, Toronto, Canada
    Haemophilia 15:227-39. 2009
    ..In this article, we review the haematological, surgical and rehabilitative considerations relevant to orthopaedic surgery in haemophilia patients with inhibitors, and provide recommendations for carrying out such procedures...
  30. doi A novel immunosuppressive pathway involving peroxynitrite-mediated [corrected] nitration of platelet antigens within antigen-presenting cells
    John W Semple
    Keenan Research Centre, Li Ka Shing Knowledge Institute, St Michael s Hospital, Toronto, Ontario, Canada
    Transfusion 48:1917-24. 2008
    ..To further analyze this, we focused on NO's major metabolite peroxynitrite (ONOO(-)) and its ability to affect PLT immunity...
  31. pmc Project examining effectiveness in clinical ethics (PEECE): phase 1-- descriptive analysis of nine clinical ethics services
    M D Godkin
    Joint Center for Bioethics, University of Toronto, Toronto, Canada
    J Med Ethics 31:505-12. 2005
    ..Best practices in clinical ethics against which one can benchmark performance have not been clearly articulated. The first step in developing benchmarks of clinical ethics services is to identify and understand current practices...
  32. ncbi Depression and mental health visits to physicians--a prospective records-based study
    Anne Rhodes
    St Michael s Hospital, Suicide Studies and The Inner City, The Arthur Sommer Rotenberg Chair in Health Research Unit, 30 Bond Street, Toronto, Ont, Canada M5B 1W8
    Soc Sci Med 62:828-34. 2006
    ..The meaning behind these findings bears further study as it may have implications for primary care reform and the design of future studies of access...
  33. ncbi Comparison of the antioxidant effects of equine estrogens, red wine components, vitamin E, and probucol on low-density lipoprotein oxidation in postmenopausal women
    B R Bhavnani
    Department of Obstetrics and Gynecology, Institute of Medical Sciences, University of Toronto, Ontario, Canada
    Menopause 8:408-19. 2001
    ....
  34. ncbi S-Adenosylmethionine decarboxylase gene expression is regulated by the cAMP signal transduction pathway in H-ras transformed fibrosarcoma cells capable of malignant progression
    R A Hurta
    Department of Laboratory Medicine and Pathobiology, St Michael s Hospital, 38 Shuter St, Toronto, Ontario, Canada, M5B 1A6
    J Cell Biochem Suppl . 2001
    ..J. Cell. Biochem. Suppl. 36: 209-221, 2001...
  35. ncbi Chinese-style barbecued meats: a public health challenge
    J Ying
    Health Promotion and Environmental Protection Office, Toronto Public Health, ON
    Can J Public Health 91:386-9. 2000
    ..e., chopping and packaging the food) as a result of lack of proper hand-washing and equipment sanitation. A risk-based food safety policy is proposed...
  36. ncbi Smooth muscle cell matrix metalloproteinase production is stimulated via alpha(v)beta(3) integrin
    M P Bendeck
    Terrence Donnelly Research Laboratories, Division of Cardiology, St Michael s Hospital, University of Toronto, Toronto, Ontario, Canada
    Arterioscler Thromb Vasc Biol 20:1467-72. 2000
    ..Thus, our results support the hypothesis that SMC alpha(v)beta(3) integrin receptors play an important role in regulating migration by stimulating SMC MMP production...
  37. ncbi Prospective randomized trial of docetaxel versus best supportive care in patients with non-small-cell lung cancer previously treated with platinum-based chemotherapy
    F A Shepherd
    University of Toronto, Toronto, and London Regional Cancer Centre, London, Ontario, Canada
    J Clin Oncol 18:2095-103. 2000
    ..Secondary end points included assessment of response (docetaxel arm only), toxicity, and quality of life...
  38. ncbi Etiology of preoperative anemia in patients undergoing scheduled cardiac surgery
    J M Karski
    Department of Anaesthesia, The Toronto General Hospital, University of Toronto, Ontario, Canada
    Can J Anaesth 46:979-82. 1999
    ..The purpose of this study was to evaluate the etiology of preoperative anemia...
  39. ncbi Plasma urokinase antigen and plasminogen activator inhibitor-1 antigen levels predict angiographic coronary restenosis
    B H Strauss
    Division of Cardiology, Terrence Donnelly Heart Centre, Hematology University of Toronto, Toronto, Ontario, Canada
    Circulation 100:1616-22. 1999
    ....
  40. ncbi Efficacy and safety of cerivastatin in primary hypercholesterolemia: a long term comparative titration study with simvastatin
    L A Leiter
    University of Toronto, Toronto, Canada
    Can J Cardiol 15:545-55. 1999
    ..To compare cerivastatin with simvastatin in their long term safety and efficacy in reducing low density lipoprotein cholesterol (LDL-C)...
  41. ncbi Comparison of performance of interns completing the old (1993) and new interactive (1997) Advanced Trauma Life Support courses
    J Ali
    Department of Surgery, University of Toronto, Ontario, Canada
    J Trauma 46:80-6. 1999
    ..The 1997 edition of the Advanced Trauma Life Support (ATLS) course emphasized interactivity as its major change. The impact of this change is assessed in this study...
  42. ncbi Alternatives to chemotherapy and radiotherapy as adjuvant treatment for lung cancer
    F A Shepherd
    Toronto Hospital, Ontario, Canada
    Lung Cancer 17:S121-36. 1997
    ..It remains only speculative at this time as to whether manipulation of abnormal genes in malignant cells will be clinically possible, and whether treatment of this sort may be applied in an adjuvant setting...
  43. ncbi Treatment of Kaposi's sarcoma after solid organ transplantation
    F A Shepherd
    Department of Medicine, The Multi Organ Transplant Program of The Toronto Hospital, University of Toronto, Ontario, Canada
    J Clin Oncol 15:2371-7. 1997
    ....
  44. ncbi An overview of the management of electrical storm
    P Dorian
    Department of Medicine, University of Toronto, Ontario
    Can J Cardiol 13:13A-17A. 1997
    ..In this article, several different clinical syndromes of electrical storm and the management of each are examined...
  45. pmc Bioethics for clinicians: 5. Substitute decision-making
    N M Lazar
    University of Toronto
    CMAJ 155:1435-7. 1996
    ....
  46. ncbi Anti-D (WinRho SD) treatment of children with chronic autoimmune thrombocytopenic purpura stimulates transient cytokine/chemokine production
    J W Semple
    Department of Laboratory Medicine and Pathobiology, St Michael s Hospital, Toronoto, Ontario, Canada
    Am J Hematol 69:225-7. 2002
    ..It is possible that the induced cytokine/chemokine storm may have an effect on several physiological processes such as those mediating either adverse effects or potentially RES phagocytic activity...
  47. pmc Influence of clarithromycin on early atherosclerotic lesions after Chlamydia pneumoniae infection in a rabbit model
    Ignatius W Fong
    Department of Medicine, Division of Infectious Disease, St Michael s Hospital and University of Toronto, 30 Bond Street, Rm 4 179C, Toronto, M5B 1W8 Ontario, Canada
    Antimicrob Agents Chemother 46:2321-6. 2002
    ..Thus, clarithromycin administration modified C. pneumoniae-induced atherosclerotic lesions and reduced the ability to detect organism in tissue. Early treatment was more effective than delayed treatment...
  48. ncbi A rabbit model for monitoring in vivo viability of human platelet concentrates using flow cytometry
    Valery Leytin
    Department of Transfusion Medicine, St Michael s Hospital, Toronto, Ontario, Canada
    Transfusion 42:711-8. 2002
    ..Viability in vivo of novel platelet components cannot be readily determined in human transfusions. Elaboration of valid animal models may be useful for this purpose...
  49. ncbi Racial inequalities in preterm delivery: issues in the measurement of psychosocial constructs
    Patricia O'Campo
    Department of Population and Family Health Sciences, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA
    Am J Obstet Gynecol 192:S56-63. 2005
    ....
  50. ncbi Early cardiac catheterization is associated with lower mortality only among high-risk patients with ST- and non-ST-elevation acute coronary syndromes: observations from the OPUS-TIMI 16 trial
    Warren J Cantor
    Department of Medicine, Division of Cardiology, St Michael s Hospital, University of Toronto, Toronto, Ontario, Canada
    Am Heart J 149:275-83. 2005
    ..The benefit of catheterization in both syndromes may depend on patient risk for adverse clinical outcomes...
  51. ncbi Barriers and facilitators in pain management in long-term care institutions: a qualitative study
    Patricia Fox
    Mobility Program Clinical Research Unit, 70 Richmond, St Michael s Hospital, 30 Bond Street, Toronto, Ontario M5B 1W8
    Can J Aging 23:269-80. 2004
    ..Innovative strategies and strong political will are needed to overcome them...
  52. ncbi Stent-graft repair of femoral pseudoaneurysm/AV fistula using a retrograde popliteal approach
    Raymond P Chan
    Division of Vascular and Interventional Radiology, St Michael s Hospital, University of Toronto, Ontario, Canada
    Cardiovasc Intervent Radiol 27:516-9. 2004
  53. ncbi Review article: patients' fears and unmet needs in inflammatory bowel disease
    E J Irvine
    Division of Gastroenterology, University of Toronto, Ontario, Canada
    Aliment Pharmacol Ther 20:54-9. 2004
    ....
  54. ncbi Cox-2 expression in the oxyphilic cells of the normal, hyperplastic, and adenomatous parathyroid gland
    C David Bell
    Division of Pathology, Department of Laboratory Medicine and Pathobiology, St Michael s Hospital, Faculty of Medicine, Toronto, Ontario, Canada
    Endocr Pathol 15:29-38. 2004
    ..It is suggested that the oncocytic cells play a role in prostaglandin metabolism within the parathyroids and may have a role in the regulation of PTH secretion...
  55. ncbi Separation and quantitative recovery of mouse serum arylesterase and carboxylesterase activity
    Philip W Connelly
    Department of Medicine, University of Toronto, and St Michael s Hospital, Toronto, Canada
    J Lipid Res 45:561-6. 2004
    ..The contribution of serum carboxylesterase to the total esterase activity significantly confounds the interpretation of total arylesterase activity in mouse serum...
  56. ncbi Hypercapnia increases cerebral tissue oxygen tension in anesthetized rats
    Gregory M T Hare
    Department of Anaesthesia, St Michael s Hospital, University of Toronto, Toronto, Ontario, Canada
    Can J Anaesth 50:1061-8. 2003
    ..To test the hypotheses that deliberate elevation of PaCO(2) increases cerebral tissue oxygen tension (PBrO(2)) by augmenting PaO(2) and regional cerebral blood flow (rCBF)...
  57. ncbi Thrombotic thrombocytopenic purpura associated with a prolactin-producing pituitary adenoma
    Kalman Kovacs
    Department of Laboratory Medicine and Pathobiology, St Michael s Hospital, University of Toronto, Toronto, Ontario, Canada
    Am J Hematol 74:55-9. 2003
    ..Further studies are required to determine whether prolactin released from the pituitary tumor in excess played a role in the formation of microthrombi causing multiple organ failure and the demise of the patient...
  58. ncbi Collagenase plaque digestion for facilitating guide wire crossing in chronic total occlusions
    Bradley H Strauss
    Roy and Ann Foss Interventional Cardiology Research Program, Terrence Donnelly Heart Center, St Michael s Hospital, Toronto, Ontario, Canada
    Circulation 108:1259-62. 2003
    ..Collagen is the predominant component of the atherosclerotic plaque. The objective of this study was to determine the efficacy and toxicity of local delivery of a collagen-degrading enzyme to facilitate guide wire crossing in CTO...
  59. ncbi A description of a psychosocial/psychoeducational intervention for persons with recurrent suicide attempts
    Yvonne Bergmans
    St Michael s Hospital University of Toronto, Toronto, Ontario, Canada
    Crisis 23:156-60. 2002
    ..Future reports will discuss the empirical evaluation of this intervention; however, the development of specific, targeted approaches for unique individuals with recurrent suicide attempts is clearly needed...
  60. ncbi Angiotensinogen M235T genotype predicts progression in chronic renal allograft dysfunction
    G V Ramesh Prasad
    Department of Medicine, University of Toronto, Toronto, Ontario, Canada
    Transplantation 75:209-16. 2003
    ..Genotypes of the renin-angiotensin system have been implicated in essential hypertension and in progression of native kidney diseases, but gene effects on progression in chronic renal allograft dysfunction are unclear...
  61. ncbi Self-reported use of mental health services versus administrative records: should we care?
    Anne E Rhodes
    Department of Psychiatry, University of Toronto, and St Michael s Hospital, Toronto, Canada
    Int J Methods Psychiatr Res 11:125-33. 2002
    ..These results suggest that recall bias may be present. Regardless of the definition of care, access for those in need remains a concern despite universal medical insurance coverage...
  62. ncbi The gut in critical illness: evidence from human studies
    J C Marshall
    Department of Surgery, University of Toronto, Ontario, Canada
    Shock 6:S10-6. 1996
    ..The challenge to replace them is no less compelling and no less treacherous than it was in the era of Metchnikoff, Lane, or their ancient forebears...

Research Grants8

  1. Health care utilitzation in homeless people
    Stephen Hwang; Fiscal Year: 2005
    ..Findings will be relevant to health care providers, insurers, and others who share a responsibility for improving the health of Americans who are homeless. ..
  2. PATHOPHYSIOLOGY OF CHRONIC CEREBRAL VASOSPASM
    Robert MacDonald; Fiscal Year: 2000
    ....
  3. PATHOPHYSIOLOGY OF CHRONIC CEREBRAL VASOSPASM
    Robert MacDonald; Fiscal Year: 2005
    ..abstract_text> ..