David J Lynn

Summary

Affiliation: Simon Fraser University
Country: Canada

Publications

  1. pmc Detecting the effects of selection at the population level in six bovine immune genes
    Abigail R Freeman
    Smurfit Institute of Genetics, Trinity College, Dublin 2, Ireland
    BMC Genet 9:62. 2008
  2. pmc InnateDB: facilitating systems-level analyses of the mammalian innate immune response
    David J Lynn
    Department of Molecular Biology and Biochemistry, Simon Fraser University, Burnaby, British Columbia, Canada
    Mol Syst Biol 4:218. 2008
  3. pmc InnateDB: systems biology of innate immunity and beyond--recent updates and continuing curation
    Karin Breuer
    Department of Molecular Biology and Biochemistry, Simon Fraser University, Burnaby, BC, V5A1S6, Canada
    Nucleic Acids Res 41:D1228-33. 2013
  4. pmc CerebralWeb: a Cytoscape.js plug-in to visualize networks stratified by subcellular localization
    Silvia Frias
    Department of Molecular Biology and Biochemistry, Simon Fraser University, Burnaby, BC V5A 1S6, Canada, EMBL Australia Group, South Australian Health and Medical Research Institute, Adelaide, SA 5000, Australia and School of Medicine, Flinders University, Bedford Park, SA 5042, Australia
    Database (Oxford) 2015:bav041. 2015
  5. ncbi request reprint Bioinformatics: implications for medical research and clinical practice
    David J Lynn
    Education Research Centre, St Vincent s University Hospital, Dublin, Ireland
    Clin Invest Med 26:70-4. 2003
  6. ncbi request reprint In silico identification of components of the Toll-like receptor (TLR) signaling pathway in clustered chicken expressed sequence tags (ESTs)
    David J Lynn
    Education and Research Centre, St Vincent s University Hospital, Dublin 4, Ireland
    Vet Immunol Immunopathol 93:177-84. 2003
  7. ncbi request reprint Bioinformatic discovery and initial characterisation of nine novel antimicrobial peptide genes in the chicken
    David J Lynn
    Education and Research Centre, St Vincent s University Hospital, 4, Dublin, Ireland
    Immunogenetics 56:170-7. 2004
  8. ncbi request reprint The synthetic form of a novel chicken beta-defensin identified in silico is predominantly active against intestinal pathogens
    Rowan Higgs
    Education and Research Centre, St Vincent s University Hospital, Dublin 4, Ireland
    Immunogenetics 57:90-8. 2005

Collaborators

  • Fiona S L Brinkman
  • Aaron Barsky
  • Dan Tulpan
  • Mario A Fares
  • Kenneth Bryan
  • Silvia Frias
  • Karin Breuer
  • Abigail R Freeman
  • Rowan Higgs
  • Carol Chen
  • Robert E W Hancock
  • Matthew R Laird
  • Geoffrey L Winsor
  • Raymond Lo
  • Amir K Foroushani
  • Anastasia Sribnaia
  • Daniel G Bradley
  • Caitriona Murray
  • Cliona O'Farrelly
  • Jessica McMahon
  • Grace Mulcahy
  • Susan Gaines
  • Tharappel James
  • Joanna Tierney
  • Andrew T Lloyd

Detail Information

Publications8

  1. pmc Detecting the effects of selection at the population level in six bovine immune genes
    Abigail R Freeman
    Smurfit Institute of Genetics, Trinity College, Dublin 2, Ireland
    BMC Genet 9:62. 2008
    ..Past adaptive change implies that more recent variation may have also been subject to selective forces...
  2. pmc InnateDB: facilitating systems-level analyses of the mammalian innate immune response
    David J Lynn
    Department of Molecular Biology and Biochemistry, Simon Fraser University, Burnaby, British Columbia, Canada
    Mol Syst Biol 4:218. 2008
    ....
  3. pmc InnateDB: systems biology of innate immunity and beyond--recent updates and continuing curation
    Karin Breuer
    Department of Molecular Biology and Biochemistry, Simon Fraser University, Burnaby, BC, V5A1S6, Canada
    Nucleic Acids Res 41:D1228-33. 2013
    ..Finally, the recent integration of bovine data makes InnateDB the first integrated network analysis platform for this agriculturally important model organism...
  4. pmc CerebralWeb: a Cytoscape.js plug-in to visualize networks stratified by subcellular localization
    Silvia Frias
    Department of Molecular Biology and Biochemistry, Simon Fraser University, Burnaby, BC V5A 1S6, Canada, EMBL Australia Group, South Australian Health and Medical Research Institute, Adelaide, SA 5000, Australia and School of Medicine, Flinders University, Bedford Park, SA 5042, Australia
    Database (Oxford) 2015:bav041. 2015
    ..innatedb.com) and Allergy and Asthma Portal (allergen.innatedb.com) database and analysis resources. Database tool URL: http://www.innatedb.com/CerebralWeb..
  5. ncbi request reprint Bioinformatics: implications for medical research and clinical practice
    David J Lynn
    Education Research Centre, St Vincent s University Hospital, Dublin, Ireland
    Clin Invest Med 26:70-4. 2003
  6. ncbi request reprint In silico identification of components of the Toll-like receptor (TLR) signaling pathway in clustered chicken expressed sequence tags (ESTs)
    David J Lynn
    Education and Research Centre, St Vincent s University Hospital, Dublin 4, Ireland
    Vet Immunol Immunopathol 93:177-84. 2003
    ..We have identified in silico the full-length sequence for liver-expressed antimicrobial peptide 2 (LEAP-2). This is the first time a non-mammalian LEAP-2 has been described...
  7. ncbi request reprint Bioinformatic discovery and initial characterisation of nine novel antimicrobial peptide genes in the chicken
    David J Lynn
    Education and Research Centre, St Vincent s University Hospital, 4, Dublin, Ireland
    Immunogenetics 56:170-7. 2004
    ..An evolutionary analysis of the gallinacin family has detected sites-primarily in the mature AMP-that are under positive selection in these molecules. The functional implications of these results are discussed...
  8. ncbi request reprint The synthetic form of a novel chicken beta-defensin identified in silico is predominantly active against intestinal pathogens
    Rowan Higgs
    Education and Research Centre, St Vincent s University Hospital, Dublin 4, Ireland
    Immunogenetics 57:90-8. 2005
    ..Antimicrobial activity of synthetic Gal-11 has been demonstrated against a range of bacteria and is predominantly active against the intestinal pathogens Salmonella typhimurium and Listeria monocytogenes...