Genomes and Genes
U Venus Onay
Affiliation: Samuel Lunenfeld Research Institute
- Methodological issues in detecting gene-gene interactions in breast cancer susceptibility: a population-based study in OntarioLaurent Briollais
Prosserman Centre for Health Research, Samuel Lunenfeld Research Institute, Mount Sinai Hospital, Toronto, M5T 3L9, Canada
BMC Med 5:22. 2007....
- SNP-SNP interactions in breast cancer susceptibilityVenüs Ummiye Onay
Fred A Litwin Centre for Cancer Genetics, Samuel Lunenfeld Research Institute, Mount Sinai Hospital, Toronto, Ontario, Canada
BMC Cancer 6:114. 2006..However, polygenic models suggest that multiple commonly occurring low to modestly penetrant SNPs of cancer related genes might have a greater effect on a disease when considered in combination...
- Genetic variants of GPX1 and SOD2 and breast cancer risk at the Ontario site of the Breast Cancer Family RegistryJulia A Knight
Division of Epidemiology and Biostatistics, Samuel Lunenfeld Research Institute, Mount Sinai Hospital, Toronto, Ontario, Canada
Cancer Epidemiol Biomarkers Prev 13:146-9. 2004..30 for carriers versus noncarriers). There is a significant trend of increasing risk with increasing number of alleles with four GCG repeats (P = 0.03). This variant has not previously been reported to be associated with breast cancer...
- Polymorphisms cMyc-N11S and p27-V109G and breast cancer risk and prognosisJane C Figueiredo
Samuel Lunenfeld Research Institute, Mount Sinai Hospital, Toronto, Ontario, Canada
BMC Cancer 7:99. 2007..In this study, we focus on a rare non-synonymous polymorphism in cMyc (N11S) and a common polymorphism in p27 (V109G) and determine their role in risk and prognosis using data collected from the Ontario Breast Cancer Family Registry...