- Inhaled anesthetic modulation of amyloid beta(1-40) assembly and growthAnna Carnini
Steacie Institute of Molecular Sciences, National Research Council, 100 Sussex Drive, Ottawa, Ontario, ON, Canada K1A 0R6
Curr Alzheimer Res 4:233-41. 2007..These data show that inhaled anesthetics lower the amyloid beta(1-40) concentration necessary to initiate oligomer formation, probably by preferential binding to intermediate oligomers en route to fibril formation...
- Inhaled anesthetic enhancement of amyloid-beta oligomerization and cytotoxicityRoderic G Eckenhoff
Department of Anesthesia, University of Pennsylvania, Philadelphia, Pennsylvania 19104 4283, USA
Anesthesiology 101:703-9. 2004..The authors hypothesize that inhaled anesthetics contribute to these effects through a durable enhancement of peptide oligomerization...
- Interactions of volatile anesthetics with neurodegenerative-disease-associated proteinsAnna Carnini
Department of Anesthesiology and Critical Care, University of Pennsylvania Health Systems, 305 John Morgan Building, 3620 Hamilton Walk, Philadelphia, PA 19104, USA
Anesthesiol Clin 24:381-405. 2006..Many opportunities exist for rapid progress at all levels on defining whether anesthetics do indeed contribute to the pathogenesis of these progressive, debilitating disorders...