J H Meyer

Summary

Country: Canada

Publications

  1. ncbi Increased left posterior parietal-temporal cortex activation after D-fenfluramine in women with panic disorder
    J H Meyer
    The Centre for Addiction and Mental Health, Department of Psychiatry, University of Toronto, Clarke Division, 250 College Street, M5T 1R8, Toronto, Ontario, Canada
    Psychiatry Res 98:133-43. 2000
  2. ncbi Prefrontal cortex 5-HT2 receptors in depression: an [18F]setoperone PET imaging study
    J H Meyer
    Clarke Institute of Psychiatry, Department of Psychiatry, University of Toronto, Ont, Canada
    Am J Psychiatry 156:1029-34. 1999
  3. ncbi Novel radiotracers for imaging the serotonin transporter by positron emission tomography: synthesis, radiosynthesis, and in vitro and ex vivo evaluation of (11)C-labeled 2-(phenylthio)araalkylamines
    A A Wilson
    PET Centre, Centre for Addiction and Mental Health, and Department of Psychiatry, University of Toronto, Toronto, Ontario M5T 1R8, Canada
    J Med Chem 43:3103-10. 2000
  4. ncbi A voxel-by-voxel analysis of [18F]setoperone PET data shows no substantial serotonin 5-HT(2A) receptor changes in schizophrenia
    N P Verhoeff
    PET Centre and Schizophrenia and Continuing Care Division, Clarke Site, Centre for Addiction and Mental Health, University of Toronto, ON, M5T 1R8, Toronto, Canada
    Psychiatry Res 99:123-35. 2000
  5. ncbi The effect of paroxetine on 5-HT(2A) receptors in depression: an [(18)F]setoperone PET imaging study
    J H Meyer
    Clarke Division, Centre for Addictions and Mental Health, Department ofPsychiatry, University of Toronto, Ontario, Canada
    Am J Psychiatry 158:78-85. 2001
  6. ncbi Occupancy of serotonin transporters by paroxetine and citalopram during treatment of depression: a [(11)C]DASB PET imaging study
    J H Meyer
    PET Centre, Centre for Addiction and Mental Health, Department of Psychiatry, University of Toronto, Ontario, Canada
    Am J Psychiatry 158:1843-9. 2001
  7. ncbi Neuromodulation of frontal and temporal cortex by intravenous d-fenfluramine: an [15O]H2O PET study in humans
    J H Meyer
    Clarke Institute of Psychiatry, Department of Psychiatry, University of Toronto, Ontario, Canada
    Neurosci Lett 207:25-8. 1996
  8. ncbi Positron emission tomography quantification of [(11)C]-DASB binding to the human serotonin transporter: modeling strategies
    N Ginovart
    PET Center, Center for Addiction and Mental Health, and University of Toronto, Toronto, Ontario, Canada
    J Cereb Blood Flow Metab 21:1342-53. 2001
  9. ncbi Changes in regional brain glucose metabolism measured with positron emission tomography after paroxetine treatment of major depression
    S H Kennedy
    Mood and Anxiety Disorders Program, Centre for Addiction and Mental Health, Clarke Site, 250 College St, Toronto, Ontario M5T 1R8, Canada
    Am J Psychiatry 158:899-905. 2001
  10. doi Serotonin transporter binding is reduced in seasonal affective disorder following light therapy
    A E Tyrer
    CAMH Research Imaging Centre and Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health, Departments of Psychiatry, Pharmacology and Toxicology, Institute of Medical Sciences, University of Toronto, Toronto, ON, Canada
    Acta Psychiatr Scand 134:410-419. 2016

Collaborators

Detail Information

Publications18

  1. ncbi Increased left posterior parietal-temporal cortex activation after D-fenfluramine in women with panic disorder
    J H Meyer
    The Centre for Addiction and Mental Health, Department of Psychiatry, University of Toronto, Clarke Division, 250 College Street, M5T 1R8, Toronto, Ontario, Canada
    Psychiatry Res 98:133-43. 2000
    ..Functional pathology in the left parietal-superior temporal cortex in panic disorder may be related to abnormal modulation by serotonin...
  2. ncbi Prefrontal cortex 5-HT2 receptors in depression: an [18F]setoperone PET imaging study
    J H Meyer
    Clarke Institute of Psychiatry, Department of Psychiatry, University of Toronto, Ont, Canada
    Am J Psychiatry 156:1029-34. 1999
    ..The objective of this study was to evaluate 5-HT2 receptors in depressed patients who were medication-free and who had not made recent suicide attempts...
  3. ncbi Novel radiotracers for imaging the serotonin transporter by positron emission tomography: synthesis, radiosynthesis, and in vitro and ex vivo evaluation of (11)C-labeled 2-(phenylthio)araalkylamines
    A A Wilson
    PET Centre, Centre for Addiction and Mental Health, and Department of Psychiatry, University of Toronto, Toronto, Ontario M5T 1R8, Canada
    J Med Chem 43:3103-10. 2000
    ..Two of the tested radiotracers, 15 and 16, have highly favorable properties for imaging SERT and will be used in pilot human PET imaging studies...
  4. ncbi A voxel-by-voxel analysis of [18F]setoperone PET data shows no substantial serotonin 5-HT(2A) receptor changes in schizophrenia
    N P Verhoeff
    PET Centre and Schizophrenia and Continuing Care Division, Clarke Site, Centre for Addiction and Mental Health, University of Toronto, ON, M5T 1R8, Toronto, Canada
    Psychiatry Res 99:123-35. 2000
    ..Thus, in agreement with the previous ROI studies, voxel-by-voxel analysis confirmed the lack of substantial 5-HT(2A)R BP differences between schizophrenic patients and control subjects...
  5. ncbi The effect of paroxetine on 5-HT(2A) receptors in depression: an [(18)F]setoperone PET imaging study
    J H Meyer
    Clarke Division, Centre for Addictions and Mental Health, Department ofPsychiatry, University of Toronto, Ontario, Canada
    Am J Psychiatry 158:78-85. 2001
    ..The objective of this study was to evaluate the effect of 6 weeks of paroxetine treatment on 5-HT(2A) receptors in depressed patients...
  6. ncbi Occupancy of serotonin transporters by paroxetine and citalopram during treatment of depression: a [(11)C]DASB PET imaging study
    J H Meyer
    PET Centre, Centre for Addiction and Mental Health, Department of Psychiatry, University of Toronto, Ontario, Canada
    Am J Psychiatry 158:1843-9. 2001
    ..This study measured the proportion of 5-HTT sites blocked during paroxetine and citalopram treatment of depression and assessed the relationship between serum paroxetine levels and the proportion of 5-HTT sites blocked...
  7. ncbi Neuromodulation of frontal and temporal cortex by intravenous d-fenfluramine: an [15O]H2O PET study in humans
    J H Meyer
    Clarke Institute of Psychiatry, Department of Psychiatry, University of Toronto, Ontario, Canada
    Neurosci Lett 207:25-8. 1996
    ..These results support further investigation with intravenous d-fenfluramine to study the net functional effects of serotonergic stimulation in health and illness...
  8. ncbi Positron emission tomography quantification of [(11)C]-DASB binding to the human serotonin transporter: modeling strategies
    N Ginovart
    PET Center, Center for Addiction and Mental Health, and University of Toronto, Toronto, Ontario, Canada
    J Cereb Blood Flow Metab 21:1342-53. 2001
    ....
  9. ncbi Changes in regional brain glucose metabolism measured with positron emission tomography after paroxetine treatment of major depression
    S H Kennedy
    Mood and Anxiety Disorders Program, Centre for Addiction and Mental Health, Clarke Site, 250 College St, Toronto, Ontario M5T 1R8, Canada
    Am J Psychiatry 158:899-905. 2001
    ..The aim of the present study was to assess the effects of successful paroxetine treatment on regional glucose metabolism in patients with major depression...
  10. doi Serotonin transporter binding is reduced in seasonal affective disorder following light therapy
    A E Tyrer
    CAMH Research Imaging Centre and Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health, Departments of Psychiatry, Pharmacology and Toxicology, Institute of Medical Sciences, University of Toronto, Toronto, ON, Canada
    Acta Psychiatr Scand 134:410-419. 2016
    ..5-HTT BPND fluctuates seasonally to a greater extent in SAD relative to health. We hypothesized that in SAD, 5-HTT BPND would be reduced in the ACC and PFC following light therapy...
  11. doi Neuroinflammation in healthy aging: a PET study using a novel Translocator Protein 18kDa (TSPO) radioligand, [(18)F]-FEPPA
    I Suridjan
    Research Imaging Centre, Centre for Addiction and Mental Health, 250 College Street, M5T 1R8, Toronto, Ontario, Canada
    Neuroimage 84:868-75. 2014
    ....
  12. ncbi Serotonin 5-HT1A receptor binding potential declines with age as measured by [11C]WAY-100635 and PET
    J Tauscher
    PET Centre, Centre for Addiction and Mental Health, Toronto, Ontario, Canada
    Neuropsychopharmacology 24:522-30. 2001
    ..Hence, careful age matching may be recommended for future studies using PET and [11C]WAY-100635 to examine 5-HT1A receptors...
  13. ncbi Noradrenergic dysfunction in the prefrontal cortex in depression: an [15O] H2O PET study of the neuromodulatory effects of clonidine
    C H Fu
    Centre for Addiction and Mental Health, Clarke Site, University of Toronto, Toronto, Canada
    Biol Psychiatry 49:317-25. 2001
    ....
  14. pmc Light therapy and serotonin transporter binding in the anterior cingulate and prefrontal cortex
    S J Harrison
    CAMH Research Imaging Centre and Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health and Departments of Psychiatry, Pharmacology and Toxicology, and Institute of Medical Sciences, University of Toronto, Toronto, ON, Canada
    Acta Psychiatr Scand 132:379-88. 2015
    ..We hypothesized that, during the fall and winter, light therapy would reduce 5-HTT BPND in the ACC and PFC, which sample brain regions involved in mood regulation...
  15. doi Relationship of monoamine oxidase A binding to adaptive and maladaptive personality traits
    A Soliman
    Vivian M Rakoff PET Imaging Centre, Centre for Addiction and Mental Health and Department of Psychiatry, University of Toronto, Toronto, Ontario, Canada
    Psychol Med 41:1051-60. 2011
    ..We hypothesized that prefrontal MAOA binding would correlate negatively with angry-hostility, a trait related to aggression/anger, and positively with traits intuitively related to adaptive investigative behavior...
  16. doi Neuroimaging markers of cellular function in major depressive disorder: implications for therapeutics, personalized medicine, and prevention
    J H Meyer
    Mood and Anxiety Division and Research Imaging Centre, Centre for Addiction and Mental Health, Department of Psychiatry, University of Toronto, Toronto, Ontario, Canada
    Clin Pharmacol Ther 91:201-14. 2012
    ....
  17. ncbi Lower dopamine transporter binding potential in striatum during depression
    J H Meyer
    PET Imaging Centre, and Mood Division, Centre for Addiction and Mental Health, Department of Psychiatry and University of Toronto, 250 College St, Toronto, Ont. M5T1R8, Canada
    Neuroreport 12:4121-5. 2001
    ..Lower DAT BP itself reduces extracellular clearance of dopamine. Patients who did not decrease their striatal DAT BP failed to compensate for low dopamine and showed greater impairment on dopamine related tests...
  18. ncbi Modeling of receptor ligand data in PET and SPECT imaging: a review of major approaches
    J H Meyer
    PET Imaging Centre, 11th Floor, Clarke Division, CAMH, 250 College St, Department of Psychiatry, University of Toronto, Ontario, Canada M5T 1R8
    J Neuroimaging 11:30-9. 2001
    ..Then the major approaches are presented under the categories of graphical or mathematical as well as invasive or noninvasive...