McMaster University

Summary

Organization: McMaster University
Country: Canada

Top Publications

  1. ncbi The experience of participation in everyday occupations for adults with obesity
    Mary A Forhan
    McMaster University, School of Rehabilitation Science, Faculty of Health Sciences, 1400 Main Street West IAHS 402, Hamilton, ON, Canada L8S 1C7
    Can J Occup Ther 77:210-8. 2010
  2. doi Fitting marginal structural models: estimating covariate-treatment associations in the reweighted data set can guide model fitting
    Eleanor M Pullenayegum
    Department of Clinical Epidemiology and Biostatistics, Biostatistics Unit, McMaster University, Hamilton, Ontario, Canada
    J Clin Epidemiol 61:875-81. 2008
  3. doi The effects of leptin on airway smooth muscle responses
    Parameswaran Nair
    Firestone Institute for Respiratory Health, St Joseph s Healthcare, Hamilton, Ontario, Canada
    Am J Respir Cell Mol Biol 39:475-81. 2008
  4. doi The effect of tobacco exposure on maternal and fetal thyroid function
    Sarah D McDonald
    Department of Obstetrics and Gynecology, Division of Maternal Fetal Medicine, McMaster University, 1200 Main Street West, HSC 3N52B, Hamilton, Ontario L8N 3Z5, Canada
    Eur J Obstet Gynecol Reprod Biol 140:38-42. 2008
  5. doi Long-distance axonal regeneration in the filum terminale of adult rats is regulated by ependymal cells
    Jacek M Kwiecien
    Department of Pathology and Molecular Medicine, McMaster University, Hamilton, Ontario, Canada
    J Neurotrauma 25:196-204. 2008
  6. ncbi Effectiveness of cholinesterase inhibitors and memantine for treating dementia: evidence review for a clinical practice guideline
    Parminder Raina
    McMaster University, Hamilton, Ontario, Canada
    Ann Intern Med 148:379-97. 2008
  7. doi Rapid point-of-care HIV testing in community-based anonymous testing program: a valuable alternative to conventional testing
    D Guenter
    Deparment of Family Medicine, McMaster University, Hamilton, Ontario, Canada
    AIDS Patient Care STDS 22:195-204. 2008
  8. doi Comparing academic performance of medical students in distributed learning sites: the McMaster experience
    Flavia Bianchi
    McMaster University, Hamilton, Ontario, Canada
    Med Teach 30:67-71. 2008
  9. ncbi Bilateral hippocampal volume increases after long-term lithium treatment in patients with bipolar disorder: a longitudinal MRI study
    Kaan Yucel
    Department of Psychiatry and Behavioural Neurosciences, McMaster University, 100 West 5th Street, Hamilton, ON, L8N 3K7, Canada
    Psychopharmacology (Berl) 195:357-67. 2007
  10. ncbi Platelet function testing: quality assurance
    Catherine P M Hayward
    Department of Pathology and Molecular Medicine, McMaster University, Hamilton, Ontario, Canada
    Semin Thromb Hemost 33:273-82. 2007

Research Grants

Detail Information

Publications62

  1. ncbi The experience of participation in everyday occupations for adults with obesity
    Mary A Forhan
    McMaster University, School of Rehabilitation Science, Faculty of Health Sciences, 1400 Main Street West IAHS 402, Hamilton, ON, Canada L8S 1C7
    Can J Occup Ther 77:210-8. 2010
    ..Obesity has been shown to influence health-related quality of life, but it is unclear how obesity influences participation in specific occupations...
  2. doi Fitting marginal structural models: estimating covariate-treatment associations in the reweighted data set can guide model fitting
    Eleanor M Pullenayegum
    Department of Clinical Epidemiology and Biostatistics, Biostatistics Unit, McMaster University, Hamilton, Ontario, Canada
    J Clin Epidemiol 61:875-81. 2008
    ..Often treatment effect estimates will be sensitive to the choice of weights. A framework within which to explore reasons for this sensitivity and to select a good weighting scheme is suggested...
  3. doi The effects of leptin on airway smooth muscle responses
    Parameswaran Nair
    Firestone Institute for Respiratory Health, St Joseph s Healthcare, Hamilton, Ontario, Canada
    Am J Respir Cell Mol Biol 39:475-81. 2008
    ..This is partly mediated by PGE(2) secretion from smooth muscle cells induced by leptin. The association between obesity and asthma is unlikely to be due to a direct effect of leptin on airway smooth muscle...
  4. doi The effect of tobacco exposure on maternal and fetal thyroid function
    Sarah D McDonald
    Department of Obstetrics and Gynecology, Division of Maternal Fetal Medicine, McMaster University, 1200 Main Street West, HSC 3N52B, Hamilton, Ontario L8N 3Z5, Canada
    Eur J Obstet Gynecol Reprod Biol 140:38-42. 2008
    ..To determine the effect of smoking on maternal and fetal thyroid function...
  5. doi Long-distance axonal regeneration in the filum terminale of adult rats is regulated by ependymal cells
    Jacek M Kwiecien
    Department of Pathology and Molecular Medicine, McMaster University, Hamilton, Ontario, Canada
    J Neurotrauma 25:196-204. 2008
    ..FT offers an excellent model to study mechanisms of axonal regeneration regulated by ependymal cells in the adult CNS...
  6. ncbi Effectiveness of cholinesterase inhibitors and memantine for treating dementia: evidence review for a clinical practice guideline
    Parminder Raina
    McMaster University, Hamilton, Ontario, Canada
    Ann Intern Med 148:379-97. 2008
    ..The effectiveness of the 5 U.S. Food and Drug Administration-approved pharmacologic therapies for dementias in achieving clinically relevant improvements is unclear...
  7. doi Rapid point-of-care HIV testing in community-based anonymous testing program: a valuable alternative to conventional testing
    D Guenter
    Deparment of Family Medicine, McMaster University, Hamilton, Ontario, Canada
    AIDS Patient Care STDS 22:195-204. 2008
    ..High-quality pretest and posttest counseling is particularly important for rapid testers with positive results. The impact of false-positive results requires further study...
  8. doi Comparing academic performance of medical students in distributed learning sites: the McMaster experience
    Flavia Bianchi
    McMaster University, Hamilton, Ontario, Canada
    Med Teach 30:67-71. 2008
    In 2004, the Michael G. DeGroote School of Medicine at McMaster University in Hamilton, Ontario, developed the McMaster Community and Rural Education program (Mac-CARE), to coordinate core rotations for undergraduate and post-graduate ..
  9. ncbi Bilateral hippocampal volume increases after long-term lithium treatment in patients with bipolar disorder: a longitudinal MRI study
    Kaan Yucel
    Department of Psychiatry and Behavioural Neurosciences, McMaster University, 100 West 5th Street, Hamilton, ON, L8N 3K7, Canada
    Psychopharmacology (Berl) 195:357-67. 2007
    ..In particular, treatment with lithium may exert long-term effects on hippocampal volume, influencing cognitive outcomes in BD patients...
  10. ncbi Platelet function testing: quality assurance
    Catherine P M Hayward
    Department of Pathology and Molecular Medicine, McMaster University, Hamilton, Ontario, Canada
    Semin Thromb Hemost 33:273-82. 2007
    ..Quality assurance issues relevant to testing platelet function are reviewed in this article, with a focus on their application to established and to new and emerging tests...
  11. ncbi Assisted reproductive technologies (ART) in Canada: 2003 results from the Canadian ART Register
    Joanne Gunby
    McMaster University, Hamilton, Ontario, Canada
    Fertil Steril 88:550-9. 2007
    ..To present the success rates of assisted reproductive technologies (ART) cycles performed in 2003 in Canada. This is the third annual report of outcomes compiled in the Canadian Assisted Reproductive Technologies Register...
  12. ncbi Immunoregulation by targeting T cells in the treatment of allergy and asthma
    Mark Larché
    Immunology and Allergy Division, Department of Medicine, McMaster University, 1200 Main Street West, Hamilton, ON L8N 3Z5, Canada
    Curr Opin Immunol 18:745-50. 2006
    ....
  13. ncbi Subjective and behavioural consequences of striatal dopamine depletion in schizophrenia--findings from an in vivo SPECT study
    Lakshmi N P Voruganti
    Department of Psychiatry and Behavioural Neurosciences, McMaster University, Hamilton, and Humber River Regional Hospital, Toronto, Ontario, Canada
    Schizophr Res 88:179-86. 2006
    ....
  14. ncbi Secretion of water and ions by malpighian tubules of larval mosquitoes: effects of diuretic factors, second messengers, and salinity
    Andrew Donini
    Department of Biology, McMaster University, Life Sciences Building, Hamilton, Ontario, Canada
    Physiol Biochem Zool 79:645-55. 2006
    ..Results indicate that changes in rearing medium salinity affect the nature and extent of stimulation of fluid and ion secretion by secretagogues...
  15. doi Consequences of transfusion of platelet antibody: a case report and literature review
    Katerina Pavenski
    Department of Medicine, and the Department of Pathology and Laboratory Medicine, McMaster University, Hamilton, Ontario, Canada
    Transfusion 48:1981-9. 2008
    ..Passive transfer of platelet (PLT) antibody by blood transfusion can lead to severe thrombocytopenia, bleeding, and an acute transfusion reaction...
  16. doi Women's care-seeking experiences after referral for postpartum depression
    Wendy Sword
    McMaster University, 1200 Main Street West, Hamilton, Ontario, Canada
    Qual Health Res 18:1161-73. 2008
    ..These findings can be used to guide clinical practice and service provision...
  17. doi Epidemiology and clinical risk factors predisposing to thromboembolism in children with cancer
    Uma Athale
    Division of Hematology Oncology, Department of Pediatrics, McMaster University, Hamilton, Ontario, Canada
    Pediatr Blood Cancer 51:792-7. 2008
    ..This retrospective cohort study aims to determine the epidemiology of TE and to identify potential risk factors for TE in children with cancer...
  18. pmc Technical factors, surgeon case volume and positive margin rates after breast conservation surgery for early-stage breast cancer
    Peter J Lovrics
    Department of Surgery, McMaster University, Hamilton, Ontario, Canada
    Can J Surg 53:305-12. 2010
    ..We assessed technical factors, surgeon and hospital case volume and margin status after BCS in early-stage breast cancer...
  19. ncbi Cytochrome P450 3A4 inhibitory activity studies within the lycorine series of alkaloids
    James McNulty
    Department of Chemistry and Chemical Biology, McMaster University, 1280 Main Street West, Hamilton, Ontario L8S 4M1, Canada
    Nat Prod Commun 5:1195-200. 2010
    ....
  20. ncbi Atmospheric remote sensing to detect effects of temperature inversions on sputum cell counts in airway diseases
    Julie Wallace
    School of Geography and Earth Sciences, McMaster University, 1280 Main Street West, Hamilton, Ontario
    Environ Res 110:624-32. 2010
    ..However, we found that monthly averages of total cell counts were strongly correlated with monthly nitrogen dioxide concentrations, an association not previously identified in the literature...
  21. doi The nurse practitioner role in pain management in long-term care
    Sharon Kaasalainen
    School of Nursing, McMaster University, Hamilton, Ontario, Canada
    J Adv Nurs 66:542-51. 2010
    ..This paper is a report of a study exploring the perceptions of long-term care team members and nurse managers about barriers and facilitators to optimal use of nurse practitioners to manage residents' pain in long-term care settings...
  22. doi Rehabilitation in bariatrics: opportunities for practice and research
    Mary Forhan
    Department of Rehabilitation Science, McMaster University, Hamilton, Ontario, Canada
    Disabil Rehabil 32:952-9. 2010
    ..Obesity is associated with a wide range of chronic illnesses and disabilities familiar to rehabilitation researchers and practitioners. Obesity discourse in the area of rehabilitation science and practice is limited...
  23. doi Likert scales, levels of measurement and the "laws" of statistics
    Geoff Norman
    McMaster University, 1200 Main St W, Hamilton, ON, L8N3Z5, Canada
    Adv Health Sci Educ Theory Pract 15:625-32. 2010
    ..Hence, challenges like those above are unfounded, and parametric methods can be utilized without concern for "getting the wrong answer"...
  24. doi Combination immunosuppressant therapy for patients with chronic refractory immune thrombocytopenic purpura
    Donald M Arnold
    Department of Medicine, Michael G DeGroote School of Medicine, McMaster University, Hamilton, ON, Canada
    Blood 115:29-31. 2010
    ..Severe adverse events did not occur. Combination immunosuppressant therapy can produce a rise in the platelet count that is sometimes sustained in refractory ITP patients...
  25. doi Physical activity and subjective well-being among people with spinal cord injury: a meta-analysis
    K A Martin Ginis
    Department of Kinesiology, McMaster University, 1280 Main Street West, Hamilton, Ontario, Canada L8S4K1
    Spinal Cord 48:65-72. 2010
    ..Meta-analysis of cross-sectional, quasi-experimental and experimental studies...
  26. doi Pemphigus vulgaris of the vagina--its cytomorphologic features on liquid-based cytology and pitfalls: case report and cytological differential diagnosis
    Kazuya Onuma
    Department of Pathology, Magee Womens Hospital, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA
    Diagn Cytopathol 37:832-5. 2009
    ..Pemphigus cells on a TP smear exhibit similar cytomorphologic features to those on a conventional smear. Recognizing euchromatin pattern and smooth nuclear contours which may be better appreciated on a TP can prevent overdiagnosis...
  27. ncbi Cross-cultural beliefs about memory and aging for self and others: South Korea and Canada
    Ellen Bouchard Ryan
    McMaster Centre for Gerontological Studies, McMaster University, Hamilton, Ontario, Canada
    Int J Aging Hum Dev 68:185-94. 2009
    ..These findings demonstrate the cross-cultural generality of negative memory stereotypes of middle and old age and the importance of self-other distinctions in age biases...
  28. doi Safety of long-acting beta-agonists: are new data really required?
    Malcolm R Sears
    Firestone Institute for Respiratory Health, St Joseph s Healthcare, McMaster University, Hamilton, ON, Canada
    Chest 136:604-7. 2009
    ..It is time to learn from the past, to rigorously avoid LABA monotherapy in asthma, and to use a LABA (when indicated) always in mandatory combination with appropriate doses of an ICS...
  29. doi Structural and electrophysiological changes in atherosclerotic radial artery grafts account for impairment of vessel reactivity
    Irem Mueed
    Department of Medicine, McMaster University, St Joseph s Healthcare, T3338, 50 Charlton Ave, Hamilton, Ontario, Canada L8N 4A6
    Atherosclerosis 206:405-10. 2009
    ..We conclude that caution should be exercised when using RA grafts with atherosclerotic lesions since they could significantly impact the clinical outcome of CABG surgery...
  30. doi Fairness and accountability for reasonableness. Do the views of priority setting decision makers differ across health systems and levels of decision making?
    Lydia Kapiriri
    McMaster University, Hamilton, Ontario, Canada
    Soc Sci Med 68:766-73. 2009
    ..However, the framework should be used with flexibility to allow for identification of elements and relevant explicit criteria (such as those identified in this study) - that may not directly fit under any of the four conditions...
  31. ncbi Mysteries and mazes: parents' experiences of children with developmental coordination disorder
    Cheryl Missiuna
    School of Rehabilitation Science, McMaster University, Hamilton, ON
    Can J Occup Ther 73:7-17. 2006
    ..Although a family-centred approach has been identified as best practice in pediatric care, the perspective of parents is often overlooked both in research and in practice...
  32. ncbi Pharmacologic interventions to reduce the risk of asthma exacerbations
    Paul M O'Byrne
    Firestone Institute for Respiratory Health, St Joseph s Hospital, 50 Charlton Avenue East, Hamilton, Ontario L8N 4A6, Canada
    Proc Am Thorac Soc 1:105-8. 2004
    ..Treatment with either leukotriene receptor antagonists or anti-IgE also reduces the risks of asthma exacerbations, but the magnitude of the benefit compared with the combination of ICS and long-acting beta(2)-agonists is not yet known...
  33. ncbi Health status and health-related quality of life associated with hemophilia
    Ronald D Barr
    McMaster University Medical Center, Hamilton Health Sciences Corporation, 1200 Main Street West, Hamilton, Ontario L85 4J9, Canada
    Am J Hematol 71:152-60. 2002
    ..Measurement of this burden, as reported here, provides a basis for future economic evaluation of the costs and consequences of health care interventions provided to this population...
  34. ncbi Methods of sputum processing for cell counts, immunocytochemistry and in situ hybridisation
    A Efthimiadis
    Firestone Institute for Respiratory Health, Hamilton, Ontario, Canada
    Eur Respir J Suppl 37:19s-23s. 2002
  35. ncbi Declining rate of folate insufficiency among adults following increased folic acid food fortification in Canada
    J G Ray
    Department of Medicine, Sunnybrook and Women s College Health Sciences Centre, Toronto, ON
    Can J Public Health 93:249-53. 2002
    ..We investigated whether the rate of folate and vitamin B12 insufficiency among adults has changed since this mandatory fortification program was implemented...
  36. ncbi Growth negatively impacts the life span of mammals
    C David Rollo
    Department of Biology, McMaster University, Hamilton, Ontario, Canada
    Evol Dev 4:55-61. 2002
    ..Proximal mechanisms for impacts of growth on longevity appear congruent with the free radical and immunological theories of aging...
  37. pmc The beginning of the research stream in family medicine residency program at McMaster University
    J Kaczorowski
    Department of Family Medicine, Faculty of Health Sciences, McMaster University, Hamilton, Ontario, Canada
    BMC Med Educ 1:1. 2001
    ..To examine research background, attitudes, knowledge and skills of family medicine residents with regard to primary care research and to compare residents who elected to participate in the research stream with those who did not...
  38. ncbi Is infant-directed speech prosody a result of the vocal expression of emotion?
    L J Trainor
    Department of Psychology, McMaster University, Hamilton, ON, Canada L8S 4K1
    Psychol Sci 11:188-95. 2000
    ..We conclude that ID prosody itself is not special. What is special is the widespread expression of emotion to infants in comparison with the more inhibited expression of emotion in typical adult interactions...
  39. ncbi Impact of right ventricular involvement on mortality and morbidity in patients with inferior myocardial infarction
    S R Mehta
    Division of Cardiology, Hamilton Health Sciences Corporation, McMaster University, Ontario, Canada
    J Am Coll Cardiol 37:37-43. 2001
    ..We sought to evaluate the prognostic impact of right ventricular (RV) myocardial involvement in patients with inferior myocardial infarction (MI)...
  40. ncbi To boil or not: drinking water for children in a periurban barrio
    J D McLennan
    Canadian Centre for Studies of Children at Risk, McMaster University, Hamilton, Ontario
    Soc Sci Med 51:1211-20. 2000
    ..Knowledge deficits may play only a limited role in determining this prevention practice. Further work is required to better identify key factors to improve this practice and hence guide health promotion efforts...
  41. ncbi Evaluations by staff, residents, and community seniors of patronizing speech in the nursing home: impact of passive, assertive, or humorous responses
    E B Ryan
    McMaster Centre for Gerontological Studies, McMaster University, Hamilton, Ontario, Canada
    Psychol Aging 15:272-85. 2000
    ....
  42. ncbi Resisting resistance: new chemical strategies for battling superbugs
    G D Wright
    Department of Biochemistry, Antimicrobial Research Centre, McMaster University, ON, L8N 3Z5, Canada
    Chem Biol 7:R127-32. 2000
    ..Recent efforts are encouraging and highlight the importance of research at the chemistry-microbiology interface in developing new approaches to tackle resistance...
  43. pmc Impact of reference standard sensitivity on accuracy of rapid antigen detection assays and a leukocyte esterase dipstick for diagnosis of Chlamydia trachomatis infection in first-void urine specimens from men
    M Chernesky
    Father Sean O Sullivan Research Center, St Joseph s Hospital, Hamilton, Ontario L8N 4A6
    J Clin Microbiol 37:2777-80. 1999
    ..These rapid chlamydial antigen tests performed reasonably well with FVU specimens, but the simple LE dipstick test, which had the highest sensitivity, would have enabled treatment of the greatest number of infected male patients...
  44. ncbi Health-related quality of life in survivors of tumours of the central nervous system in childhood--a preference-based approach to measurement in a cross-sectional study
    R D Barr
    Department of Pediatrics, McMaster University, Hamilton, Ontario, Canada
    Eur J Cancer 35:248-55. 1999
    ..The usefulness of measures of health status and health-related quality of life, in children surviving brain tumours, has been demonstrated by this study...
  45. ncbi Role of resistance training in heart disease
    N McCartney
    Department of Kinesiology, McMaster University, Hamilton, Ontario, Canada
    Med Sci Sports Exerc 30:S396-402. 1998
    ..Future studies are needed in patients with congestive heart failure and orthotopic heart transplantation; muscle weakness is common in these groups and makes them excellent candidates to benefit from this form of exercise...
  46. ncbi Assessing nebulizer performance
    Myrna B Dolovich
    Departments of Medicine and Nuclear Medicine, McMaster University, Hamilton, Ontario, Canada
    Respir Care 47:1290-301; discussion 1301-4. 2002
    ....
  47. ncbi Fluoxetine improves functional work capacity in women with premenstrual dysphoric disorder
    M Steiner
    Women s Health Concerns Clinic, St Joseph s Healthcare, Hamilton, ON, Canada
    Arch Womens Ment Health 6:71-7. 2003
    ..Our results demonstrate that fluoxetine at a relatively low dose of 20 mg/d quickly reduced symptoms that negatively affect work capacity and was well tolerated...
  48. pmc Cholesterol in bilayers of sphingomyelin or dihydrosphingomyelin at concentrations found in ocular lens membranes
    Richard M Epand
    Department of Biochemistry, McMaster University, Health Sciences Center, Hamilton, Ontario L8N 3Z5, Canada
    Biophys J 84:3102-10. 2003
    ..Our studies show that the ratio of sphingomyelin to dihydrosphingomyelin can affect the rate of formation of these cholesterol crystallites and thus play a role in the membrane of cells of the lens, affecting ocular function...
  49. ncbi Longitudinal follow-up of bone mineral density in children with nephrotic syndrome and the role of calcium and vitamin D supplements
    Sanjeev Gulati
    Department of Nephrology, Sanjay Gandhi Post Graduate Institute of Medical Sciences, Raebareli Road, Lucknow, India 226014
    Nephrol Dial Transplant 20:1598-603. 2005
    ..In this study, we report the longitudinal follow-up of these children and the role of calcium and vitamin D supplements...
  50. ncbi Handheld computers and paper diaries for documenting the use of factor concentrates used in haemophilia home therapy: a qualitative study
    E Arnold
    Department of Medicine, McMaster University, Hamilton, ON, Canada
    Haemophilia 11:216-26. 2005
    ..In addition, given the evidence of both patients' preference for handheld computers, and the effectiveness of this approach documented in an RCT, switching to handheld computers is likely to improve record keeping...
  51. ncbi The diagnostic evaluation of deep vein thrombosis
    Simon J McRae
    Department of Medicine, McMaster University, Hamilton, Ontario, Canada
    Am Heart Hosp J 2:205-10. 2004
    ..The optimal strategy at individual institutions is dependent on local expertise and cost. Magnetic resonance venography has the potential to be used as a stand-alone test for DVT but requires further evaluation...
  52. ncbi The prevalence and evolution of sex in microorganisms
    Jianping Xu
    Department of Biology, McMaster University, 1280 Main Street West, Hamilton, ON L8S 4K1, Canada
    Genome 47:775-80. 2004
    ..It is argued that microbes are excellent model organisms to explore the mechanisms responsible for the evolution of sex...
  53. ncbi Rationale, design, and baseline characteristics of 2 large, simple, randomized trials evaluating telmisartan, ramipril, and their combination in high-risk patients: the Ongoing Telmisartan Alone and in Combination with Ramipril Global Endpoint Trial/Telmi
    Koon Teo
    McMaster University Medical Centre, 1200 Main Street West, Hamilton, Ontario, Canada L8N 3Z5
    Am Heart J 148:52-61. 2004
    ..Currently, there is uncertainty about the role of ARBs when used alone or in combination with an ACE inhibitor in high-risk populations with controlled hypertension...
  54. ncbi Use of the paired-comparison technique to determine the most valued qualities of the McMaster Medical Programme Admissions Process
    M L Marrin
    Department of Pediatrics, McMaster University, Hamilton, Ontario, Canada
    Adv Health Sci Educ Theory Pract 9:129-35. 2004
    The Undergraduate Medical Programme at McMaster University selects students using a comprehensive set of tools...
  55. ncbi Dichlorodiphenylchloroethylene elevates cytosolic calcium concentrations and oscillations in primary cultures of human granulosa-lutein cells
    E V Younglai
    Department of Obstetrics and Gynecology, Reproductive Biology Division, McMaster University, Health Sciences Centre, Hamilton, Ontario, Canada
    Biol Reprod 70:1693-700. 2004
    ..Our data therefore highlight a novel mechanism through which DDE can alter endocrine homeostasis and possibly act as an endocrine toxicant...
  56. pmc Prenatal HIV tests. Routine testing or informed choice?
    Dale Guenter
    Department of Family Medicine, McMaster University, Hamilton, Ont
    Can Fam Physician 49:1334-40. 2003
    ..To examine how prenatal care providers responded to a new provincial policy of offering HIV testing to all prenatal patients, and to determine factors associated with self-reported high testing rates...
  57. ncbi Multisensory integration in speed estimation during self-motion
    Hong Jin Sun
    Department of Psychology, McMaster University, Hamilton, Ontario, Canada
    Cyberpsychol Behav 6:509-18. 2003
    ..These results suggest an important role for proprioceptive information in speed estimation during self-motion...
  58. ncbi Reduction of out-of-hospital symptomatic venous thromboembolism by extended thromboprophylaxis with low-molecular-weight heparin following elective hip arthroplasty: a systematic review
    Martin O'Donnell
    Henderson Research Centre, Hamilton, Ontario, Canada
    Arch Intern Med 163:1362-6. 2003
    ....
  59. ncbi Modification of clearance of therapeutic and potentially therapeutic proteins
    W P Sheffield
    Department of Pathology and Molecular Medicine, HSC 4N66, McMaster University, 1200 Main Street West, Hamilton, Ontario, Canada L8N 3Z5
    Curr Drug Targets Cardiovasc Haematol Disord 1:1-22. 2001
    ..With the explosive growth of genomic and proteomic information, an exponentially increasing number of engineered proteins are likely to be developed, with a probable need for clearance-related modification...
  60. ncbi Psychopathology and social competencies of adolescents who were extremely low birth weight
    Saroj Saigal
    Department of Pediatrics, McMaster University, Hamilton, Ontario, Canada
    Pediatrics 111:969-75. 2003
    ..We have previously shown that infants who were extremely low birth weight (ELBW) are particularly vulnerable to problems related to inattention and hyperactivity at school age. It is not known whether these problems persist to adolescence...
  61. ncbi Poverty and mental health: a qualitative study of residential care facility tenants
    Robert D Wilton
    School of Geography and Geology, McMaster University, Hamilton, ON, Canada
    Community Ment Health J 39:139-56. 2003
    ..Findings suggest that a failure to recognize poverty as a key mental health policy issue will continue to constrain efforts to facilitate consumer empowerment and social integration...
  62. ncbi Reduced aggressiveness and low testosterone levels in autoimmune MRL-lpr males
    B Sakic
    Department of Psychiatry, McMaster University, Hamilton, Ontario, Canada
    Physiol Behav 63:305-9. 1998
    ..The question of whether immune activation alters behavior by a direct effect on the nervous system, or also via the endocrine system, requires further study...

Research Grants49

  1. A randomized trial of influenza vaccination of Hutterite children
    Mark Loeb; Fiscal Year: 2006
    ..We believe that the trial we propose will lead to important data that can inform policy on influenza immunization strategy. ..
  2. Improving Outcomes in Pharmacotherapy of Social Phobia
    Michael Van Ameringen; Fiscal Year: 2007
    ..Anxiety Disorders Program at the University of California San Diego, and the Anxiety Disorders Clinic at McMaster University. The CMSD mechanism is being employed to take advantage of each of the sites' previous experience with the ..
  3. Improving Outcomes in Pharmacotherapy of Social Phobia
    Michael Van Ameringen; Fiscal Year: 2009
    ..Anxiety Disorders Program at the University of California San Diego, and the Anxiety Disorders Clinic at McMaster University. The CMSD mechanism is being employed to take advantage of each of the sites' previous experience with ..
  4. Adult Functioning of Extremely Low Birthweight Infants
    Saroj Saigal; Fiscal Year: 2004
    ..abstract_text> ..
  5. The Natural History of Venous Thromboembolism in the Elderly
    Frederick Spencer; Fiscal Year: 2007
    ..We will also examine how elderly patients with venous thromboembolism are currently being treated, whether some patients are at risk for inappropriate or under treatment, and the relationship of treatment to future complications. ..
  6. The Natural History of Venous Thromboembolism in the Elderly
    Frederick A Spencer; Fiscal Year: 2010
    ..We will also examine how elderly patients with venous thromboembolism are currently being treated, whether some patients are at risk for inappropriate or under treatment, and the relationship of treatment to future complications. ..
  7. Monitoring Trends in Venous Thromboembolism
    Frederick Spencer; Fiscal Year: 2006
    ..Implementation of this registry will set the stage for systematic long-term surveillance of this medically important Problem. ..
  8. The Worcester Venous Thromboembolism Study
    FREDERICK A contact SPENCER; Fiscal Year: 2010
    ..S. as well as deficiencies in current management practices. This information will set the stage for future studies designed to address these shortcomings. ..
  9. The Natural History of Venous Thromboembolism in the Elderly
    Frederick Spencer; Fiscal Year: 2009
    ..We will also examine how elderly patients with venous thromboembolism are currently being treated, whether some patients are at risk for inappropriate or under treatment, and the relationship of treatment to future complications. ..
  10. CLINICAL SEARCH RETRIEVAL FROM FOUR ELECTRONIC DATABASES
    R Haynes; Fiscal Year: 2007
    ..g., sensitivity); and evaluating the usefulness of the clinical hedges in the intended users group, clinicians. ..
  11. Clinical Search Retrieval from 4 Electronic Databases
    R Haynes; Fiscal Year: 2003
    ..Articles are defined as having relevant content and meeting basic methodologic criteria for clinical practice by the hand search. The operating characteristics of these strategies are determined in the 4 electronic databases. ..
  12. CLINICAL SEARCH RETRIEVAL FROM FOUR ELECTRONIC DATABASES
    R Haynes; Fiscal Year: 2001
    ..The sensitivity, specificity, accuracy and precision of the search strategies will be determined in each of the 4 electronic databases. ..
  13. PARTICIPATION OF CHILDREN WITH PHYSICAL DISABILITIES
    Mary Law; Fiscal Year: 2002
    ..The proposed project, from the Neurodevelopmental Clinical Research Unit (NCRU) at McMaster University, is a longitudinal study of children with physical disabilities aged 5- 13 years to determine the child, ..
  14. Family-centered functional therapy for cerebral palsy
    Mary Law; Fiscal Year: 2007
    ..We hypothesize that the FCFT approach will significantly improve activity and participation outcomes while leading to no significant decreases in body function and structure outcomes. ..
  15. Role of DAP12 in type 1 anti-mycobacterial immunity
    Zhou Xing; Fiscal Year: 2005
    ..We strongly believe that our studies will provide new insights into the mechanisms of type 1 anti-microbial immunity and novel targets for immune modulation. ..
  16. Associative Contributions to Drug Tolerance
    Shepard Siegel; Fiscal Year: 2004
    ..The results will also be useful in designing learning-based treatment strategies for drug dependence (so-called "cue- exposure" treatment). ..
  17. BRAIN CELL DEATH IN MRL MICE: TARGETS AND MECHANISMS
    Boris Sakic; Fiscal Year: 2004
    ..abstract_text> ..
  18. ASSOCIATE CONTRIBUTIONS TO DRUG TOLERANCE
    Shepard Siegel; Fiscal Year: 2000
    ..The results will also be useful in designing learning-based treatment strategies for drug dependence (so-called "cue-exposure" treatment). ..
  19. Use of Health and Social Services Following Work Injury
    Harry Shannon; Fiscal Year: 2004
    ..abstract_text> ..
  20. PERCEPTUAL AND MOTOR BEHAVIOR IN DOWN SYNDROME
    Digby Elliott; Fiscal Year: 2001
    ....