George Thanassoulis

Summary

Affiliation: McGill University
Country: Canada

Publications

  1. doi request reprint Individualized Statin Benefit for Determining Statin Eligibility in the Primary Prevention of Cardiovascular Disease
    George Thanassoulis
    From Preventive and Genomic Cardiology, Department of Medicine, McGill University Health Center and Research Institute, Montreal, QC, Canada G T, A D S KenAnCo Biostatistics, San Antonio, TX K W, K K Department of Medicine, University of Texas Health Science Center at San Antonio K W Duke Clinical Research Institute, Durham, NC M J P and Harvard Clinical Research Institute and Brigham and Women s Hospital, Boston, MA C P C
    Circulation 133:1574-81. 2016
  2. pmc Lipoprotein (a) in calcific aortic valve disease: from genomics to novel drug target for aortic stenosis
    George Thanassoulis
    Preventive and Genomic Cardiology, McGill University Health Center and Research Institute and Department of Medicine, McGill University, Montreal, QC, Canada
    J Lipid Res 57:917-24. 2016
  3. doi request reprint Mendelian randomization: how genetics is pushing the boundaries of epidemiology to identify new causes of heart disease
    George Thanassoulis
    McGill University Health Centre and Research Institute, Montreal, Quéebec, Canada
    Can J Cardiol 29:30-6. 2013
  4. doi request reprint Sex Differences in Clinical Outcomes After Premature Acute Coronary Syndrome
    Roxanne Pelletier
    Divisions of Clinical Epidemiology and General Internal Medicine, The Research Institute of the McGill University Health Centre, Montreal, Quebec, Canada
    Can J Cardiol 32:1447-1453. 2016
  5. doi request reprint Potential factors associated with fruit and vegetable intake after premature acute coronary syndrome: a prospective cohort study
    Sylvie S L Leung Yinko
    a Department of Epidemiology, Biostatistics and Occupational Health, McGill University, Montreal, Quebec, Canada
    Int J Food Sci Nutr 66:943-9. 2015
  6. doi request reprint Comparison of coronary calcium screening versus broad statin therapy for patients at intermediate cardiovascular risk
    Allan D Sniderman
    Division of Cardiology, Royal Victoria Hospital, McGill University Health Centre, Montreal, Quebec, Canada
    Am J Cardiol 110:530-3. 2012
  7. doi request reprint Depression and disease severity in patients with premature acute coronary syndrome
    Roxanne Pelletier
    Division of Clinical Epidemiology, The Research Institute of the McGill University Health Centre, Montreal, Quebec, Canada
    Am J Med 127:87-93.e1-2. 2014
  8. doi request reprint Sex Versus Gender-Related Characteristics: Which Predicts Outcome After Acute Coronary Syndrome in the Young?
    Roxanne Pelletier
    Divisions of General Internal Medicine and of Clinical Epidemiology, Department of Medicine, The Research Institute of the McGill University Health Centre, Montreal, Quebec, Canada
    J Am Coll Cardiol 67:127-35. 2016
  9. doi request reprint Review of published cases of adverse cardiovascular events after ingestion of energy drinks
    Michael Goldfarb
    Center for Preventive and Genomic Cardiology, Divisions of Cardiology and Clinical Epidemiology, Department of Medicine, McGill University Health Centre, Montreal, Canada Electronic address
    Am J Cardiol 113:168-72. 2014
  10. pmc Relations of change in plasma levels of LDL-C, non-HDL-C and apoB with risk reduction from statin therapy: a meta-analysis of randomized trials
    George Thanassoulis
    Preventive and Genomic Cardiology, McGill University Health Centre, Department of Medicine, Montreal, Quebec, Canada
    J Am Heart Assoc 3:e000759. 2014

Collaborators

Detail Information

Publications22

  1. doi request reprint Individualized Statin Benefit for Determining Statin Eligibility in the Primary Prevention of Cardiovascular Disease
    George Thanassoulis
    From Preventive and Genomic Cardiology, Department of Medicine, McGill University Health Center and Research Institute, Montreal, QC, Canada G T, A D S KenAnCo Biostatistics, San Antonio, TX K W, K K Department of Medicine, University of Texas Health Science Center at San Antonio K W Duke Clinical Research Institute, Durham, NC M J P and Harvard Clinical Research Institute and Brigham and Women s Hospital, Boston, MA C P C
    Circulation 133:1574-81. 2016
    ....
  2. pmc Lipoprotein (a) in calcific aortic valve disease: from genomics to novel drug target for aortic stenosis
    George Thanassoulis
    Preventive and Genomic Cardiology, McGill University Health Center and Research Institute and Department of Medicine, McGill University, Montreal, QC, Canada
    J Lipid Res 57:917-24. 2016
    ....
  3. doi request reprint Mendelian randomization: how genetics is pushing the boundaries of epidemiology to identify new causes of heart disease
    George Thanassoulis
    McGill University Health Centre and Research Institute, Montreal, Quéebec, Canada
    Can J Cardiol 29:30-6. 2013
    ....
  4. doi request reprint Sex Differences in Clinical Outcomes After Premature Acute Coronary Syndrome
    Roxanne Pelletier
    Divisions of Clinical Epidemiology and General Internal Medicine, The Research Institute of the McGill University Health Centre, Montreal, Quebec, Canada
    Can J Cardiol 32:1447-1453. 2016
    ..We revisited this issue with contemporary data from the Gender and Sex Determinants of Cardiovascular Disease: From Bench to Beyond Premature Acute Coronary Syndrome (GENESIS-PRAXY), a multicentre prospective cohort study...
  5. doi request reprint Potential factors associated with fruit and vegetable intake after premature acute coronary syndrome: a prospective cohort study
    Sylvie S L Leung Yinko
    a Department of Epidemiology, Biostatistics and Occupational Health, McGill University, Montreal, Quebec, Canada
    Int J Food Sci Nutr 66:943-9. 2015
    ..More research is needed to assess effective strategies to increase fruit and vegetable intake among patients with premature ACS so that they meet dietary recommendations. ..
  6. doi request reprint Comparison of coronary calcium screening versus broad statin therapy for patients at intermediate cardiovascular risk
    Allan D Sniderman
    Division of Cardiology, Royal Victoria Hospital, McGill University Health Centre, Montreal, Quebec, Canada
    Am J Cardiol 110:530-3. 2012
    ..In conclusion, even in the short term, the broad statin prevention strategy would be at least as effective in decreasing clinical events but with greater net savings than a prevention strategy using coronary calcium screening...
  7. doi request reprint Depression and disease severity in patients with premature acute coronary syndrome
    Roxanne Pelletier
    Division of Clinical Epidemiology, The Research Institute of the McGill University Health Centre, Montreal, Quebec, Canada
    Am J Med 127:87-93.e1-2. 2014
    ..We assessed whether major depression and depressive symptoms were associated with worse cardiovascular disease severity in patients with premature acute coronary syndrome, and we assessed sex differences in these relationships...
  8. doi request reprint Sex Versus Gender-Related Characteristics: Which Predicts Outcome After Acute Coronary Syndrome in the Young?
    Roxanne Pelletier
    Divisions of General Internal Medicine and of Clinical Epidemiology, Department of Medicine, The Research Institute of the McGill University Health Centre, Montreal, Quebec, Canada
    J Am Coll Cardiol 67:127-35. 2016
    ..Gender-related characteristics explain some differences in access to care for premature acute coronary syndrome (ACS); whether they are associated with cardiovascular outcomes is unknown...
  9. doi request reprint Review of published cases of adverse cardiovascular events after ingestion of energy drinks
    Michael Goldfarb
    Center for Preventive and Genomic Cardiology, Divisions of Cardiology and Clinical Epidemiology, Department of Medicine, McGill University Health Centre, Montreal, Canada Electronic address
    Am J Cardiol 113:168-72. 2014
    ....
  10. pmc Relations of change in plasma levels of LDL-C, non-HDL-C and apoB with risk reduction from statin therapy: a meta-analysis of randomized trials
    George Thanassoulis
    Preventive and Genomic Cardiology, McGill University Health Centre, Department of Medicine, Montreal, Quebec, Canada
    J Am Heart Assoc 3:e000759. 2014
    ..Reductions in LDL-C, non-HDL-C, or apoB can all be used but which most closely relates to benefit, as defined by the reduction in events on statin treatment, is not established...
  11. pmc Lipoprotein(a) Interactions With Low-Density Lipoprotein Cholesterol and Other Cardiovascular Risk Factors in Premature Acute Coronary Syndrome (ACS)
    Mehdi Afshar
    Department of Medicine, McGill University, Montreal, Quebec, Canada Preventive and Genomic Cardiology, McGill University Health Center and Research Institute, Montreal, Quebec, Canada
    J Am Heart Assoc 5:. 2016
    ..Identifying interactions between Lp(a) and other risk factors could identify individuals at increased risk for Lp(a)-mediated disease...
  12. doi request reprint Association Between Family History, a Genetic Risk Score, and Severity of Coronary Artery Disease in Patients With Premature Acute Coronary Syndromes
    Waseem Hindieh
    From the Department of Medicine, McGill University, Montreal, Quebec, Canada W H, L P, C L, J C E, G T Department of Medicine, University of Toronto, Toronto, Ontario, Canada A C, H A L and McGill University Health Center Research Institute, Montreal, QC, Canada L D, J C E
    Arterioscler Thromb Vasc Biol 36:1286-92. 2016
    ..We sought to determine whether the presence of these risk factors, either individually or together, was associated with a higher burden of angiographic coronary artery disease...
  13. pmc Age and Cardiovascular Risk Attributable to Apolipoprotein B, Low-Density Lipoprotein Cholesterol or Non-High-Density Lipoprotein Cholesterol
    Allan D Sniderman
    McGill University, Montreal, Canada
    J Am Heart Assoc 5:. 2016
    ..Higher concentrations of the apolipoprotein B (apoB) lipoproteins increase the risk of cardiovascular disease. However, whether the risk associated with apoB lipoproteins varies with age has not been well examined...
  14. doi request reprint Sex- and gender-related risk factor burden in patients with premature acute coronary syndrome
    Jin Choi
    Division of Clinical Epidemiology, McGill University Health Centre, Montreal, Quebec, Canada
    Can J Cardiol 30:109-17. 2014
    ..Few contemporary data exist on traditional (TRF) and non-TRF (NTRF) burden in patients with premature acute coronary syndrome (ACS)...
  15. doi request reprint Screening Strategies and Primary Prevention Interventions in Relatives of People With Coronary Artery Disease: A Systematic Review and Meta-analysis
    Michael Goldfarb
    Department of Medicine, Division of Cardiology, McGill University Health Centre, Montreal, Quebec, Canada Preventive and Genomic Cardiology, McGill University Health Centre, Montreal, Quebec, Canada
    Can J Cardiol 31:649-57. 2015
    ..Relatives of people with coronary artery disease are at high risk of cardiovascular (CV) disease, but the effect of focused screening and treatment of this population is uncertain...
  16. ncbi request reprint Estimating the Population Impact of Lp(a) Lowering on the Incidence of Myocardial Infarction and Aortic Stenosis-Brief Report
    Mehdi Afshar
    From the Department of Medicine, McGill University, Montreal, Quebec, Canada M A, A D S, G T Preventive and Genomic Cardiology, McGill University Health Center and Research Institute, Montreal, Quebec, Canada M A, A D S, G T Department of Clinical Biochemistry and The Copenhagen General Population Study, Herlev and Gentofte Hospital, Copenhagen University Hospital, Denmark P R K, B G N KenAnCo Biostatistics, San Antonio, TX K W Faculty of Health and Medical Sciences, University of Copenhagen, Denmark B G N The Copenhagen City Heart Study, Frederiksberg Hospital, Copenhagen University Hospital, Denmark B G N and Department of Clinical Epidemiology, McGill University Health Center, Montreal, Quebec, Canada G T
    Arterioscler Thromb Vasc Biol 36:2421-2423. 2016
    ..We sought to estimate the population impact of Lp(a) lowering that could be achieved in primary prevention using the therapies in development...
  17. pmc Utility of a genetic risk score to predict recurrent cardiovascular events 1 year after an acute coronary syndrome: A pooled analysis of the RISCA, PRAXY, and TRIUMPH cohorts
    Christopher Labos
    Department of Epidemiology, Biostatistics and Occupational Health, McGill University, Montreal, QC, Canada
    Atherosclerosis 242:261-7. 2015
    ..We sought to determine whether a GRS would predict early recurrent cardiovascular events within 1 year of ACS...
  18. pmc The causal exposure model of vascular disease
    Allan D Sniderman
    Mike Rosenbloom Laboratory for Cardiovascular Research, McGill University Health Centre, Montreal, QC, Canada
    Clin Sci (Lond) 122:369-73. 2012
    ..Preventing the development of advanced atherosclerotic lesions by treating the causes of vascular disease is the simplest, surest and most effective way to prevent clinical events...
  19. doi request reprint Limitations in the conventional assessment of the incremental value of predictors of cardiovascular risk
    Allan D Sniderman
    aMike Rosenbloom Laboratory for Cardiovascular Research, McGill University Health Centre, Montreal, Quebec, Canada bDepartment of Biostatistics and Bioinformatics, Duke University, DCRI, Durham, North Carolina, USA cDepartment of Medicine, Royal Victoria Hospital, McGill University Health Centre, Montreal, Quebec, Canada
    Curr Opin Lipidol 26:210-4. 2015
    ..This article demonstrates this conclusion to be invalid...
  20. doi request reprint Fish consumption and acute coronary syndrome: a meta-analysis
    Sylvie S L Leung Yinko
    Department of Epidemiology, Biostatistics and Occupational Health, McGill University, Montreal, Quebec, Canada Division of Clinical Epidemiology, Research Institute of McGill University Health Centre, Montreal, Quebec, Canada
    Am J Med 127:848-57.e2. 2014
    ..Findings on the association between fish consumption and acute coronary syndrome are inconsistent. We assessed the role of fish consumption in acute coronary syndrome by conducting a dose-response meta-analysis...
  21. pmc Do statins lower testosterone and does it matter?
    Allan D Sniderman
    Division of Cardiology, McGill University Health Centre, 687 Pine Avenue West, Montreal, QC H3A 1A1, Canada
    BMC Med 11:58. 2013
    ..We treat individuals not groups. Averages do not disclose enough about the risks and benefits of drugs. See related research article here http://www.biomedcentral.com/1741-7015/11/57...
  22. pmc A genetic risk score is associated with incident cardiovascular disease and coronary artery calcium: the Framingham Heart Study
    George Thanassoulis
    Division of Cardiology and Clinical Epidemiology, McGill University Health Center and McGill University, Montreal, Quebec, Canada
    Circ Cardiovasc Genet 5:113-21. 2012
    ..Limited data exist regarding the use of a genetic risk score (GRS) for predicting risk of incident cardiovascular disease (CVD) in US-based samples...