Peter T Macklem

Summary

Affiliation: McGill University
Country: Canada

Publications

  1. doi Towards a definition of life
    Peter T Macklem
    Meakins Christie Laboratories, Montreal Chest Institute, McGill University Health Centre Research Institute, Montreal
    Perspect Biol Med 53:330-40. 2010
  2. ncbi A century of the mechanics of breathing
    Peter T Macklem
    Am J Respir Crit Care Med 170:10-5. 2004
  3. doi Emergent phenomena and the secrets of life
    Peter T Macklem
    McGill University Health Centre Research Institute, Montreal, Canada
    J Appl Physiol 104:1844-6. 2008
  4. ncbi Chest wall dynamics and muscle recruitment during professional flute playing
    Isabelle Cossette
    Music Education Area, Department of Music, Schulich School of Music, McGill University, Montreal, Quebec, Canada
    Respir Physiol Neurobiol 160:187-95. 2008
  5. ncbi Respiratory muscle dynamics and control during exercise with externally imposed expiratory flow limitation
    Andrea Aliverti
    Centro di Bioingegneria, Fondazione Don Gnocchi e Politecnico I 20148 Milano, Italy
    J Appl Physiol (1985) 92:1953-63. 2002
  6. ncbi Phonospirometry for noninvasive measurement of ventilation: methodology and preliminary results
    Cheng Li Que
    Meakins Christie Laboratories, Montreal Chest Institute, Royal Victoria Hospital, Montreal, Quebec H2X 2P2, Canada
    J Appl Physiol 93:1515-26. 2002
  7. doi Last Word on Point:Counterpoint: The major limitation to exercise performance in COPD is 1) inadequate energy supply to the respiratory and locomotor muscles, 2) lower limb muscle dysfunction, 3) dynamic hyperinflation
    Andrea Aliverti
    TBM Lab, Dipartimento di Bioingegneria, Politecnico di Milano, Italy
    J Appl Physiol 105:763. 2008
  8. doi The major limitation to exercise performance in COPD is inadequate energy supply to the respiratory and locomotor muscles
    Andrea Aliverti
    TBL Lab, Dipartimento di Bioingegneria, Politecnico di Milano, Italy
    J Appl Physiol 105:749-51; discussion 755-7. 2008
  9. doi Dividing the FEV1 into its component parts
    Peter T Macklem
    J Appl Physiol 105:392; author reply 393. 2008
  10. pmc Canada's contribution to respiratory physiology and pathophysiology
    Peter T Macklem
    McGill University Health Centre Research Institute, Montreal, Canada
    Can Respir J 14:383-92. 2007

Collaborators

  • Isabelle Cossette
  • A Aliverti
  • P Agostoni
  • Giorgio Scano
  • Roberto Duranti
  • Henry E Fessler
  • Cliff K Choong
  • Riccardo Pellegrino
  • Raffaele Dellaca
  • Cheng Li Que
  • Iacopo Iandelli
  • Kimiaki Chino
  • Stephen S Lefrak
  • Jason C Woods
  • James C Hogg
  • John A Pierce
  • Mark S Conradi
  • Joel D Cooper
  • Dimitry A Yablonskiy
  • Alessandro Locatelli
  • Stefania Bertini
  • Vito Brusasco
  • Pamela Lotti
  • Pawel Sliwinski
  • Sheng Yan
  • Christof Kolmaga
  • Bengt Kayser
  • Louis Gilles Durand
  • Susan Kelly
  • Antonio Pedotti
  • Suzanne M Kelly
  • Stephen J Cala

Detail Information

Publications15

  1. doi Towards a definition of life
    Peter T Macklem
    Meakins Christie Laboratories, Montreal Chest Institute, McGill University Health Centre Research Institute, Montreal
    Perspect Biol Med 53:330-40. 2010
    ..Understanding life in these terms may provide new insights into what constitutes health and lead to new theories of disease...
  2. ncbi A century of the mechanics of breathing
    Peter T Macklem
    Am J Respir Crit Care Med 170:10-5. 2004
  3. doi Emergent phenomena and the secrets of life
    Peter T Macklem
    McGill University Health Centre Research Institute, Montreal, Canada
    J Appl Physiol 104:1844-6. 2008
  4. ncbi Chest wall dynamics and muscle recruitment during professional flute playing
    Isabelle Cossette
    Music Education Area, Department of Music, Schulich School of Music, McGill University, Montreal, Quebec, Canada
    Respir Physiol Neurobiol 160:187-95. 2008
    ....
  5. ncbi Respiratory muscle dynamics and control during exercise with externally imposed expiratory flow limitation
    Andrea Aliverti
    Centro di Bioingegneria, Fondazione Don Gnocchi e Politecnico I 20148 Milano, Italy
    J Appl Physiol (1985) 92:1953-63. 2002
    ..These results suggest a vicious cycle in which EFLe decreases Uab, increasing Pab and exacerbating the hypercapnia, which increases central drive increasing Pab even more, leading to further CO2 retention, and so forth...
  6. ncbi Phonospirometry for noninvasive measurement of ventilation: methodology and preliminary results
    Cheng Li Que
    Meakins Christie Laboratories, Montreal Chest Institute, Royal Victoria Hospital, Montreal, Quebec H2X 2P2, Canada
    J Appl Physiol 93:1515-26. 2002
    ..We conclude that phonospirometry measures ventilation reasonably accurately without mouthpiece, nose clip, or rigid postural constraints...
  7. doi Last Word on Point:Counterpoint: The major limitation to exercise performance in COPD is 1) inadequate energy supply to the respiratory and locomotor muscles, 2) lower limb muscle dysfunction, 3) dynamic hyperinflation
    Andrea Aliverti
    TBM Lab, Dipartimento di Bioingegneria, Politecnico di Milano, Italy
    J Appl Physiol 105:763. 2008
  8. doi The major limitation to exercise performance in COPD is inadequate energy supply to the respiratory and locomotor muscles
    Andrea Aliverti
    TBL Lab, Dipartimento di Bioingegneria, Politecnico di Milano, Italy
    J Appl Physiol 105:749-51; discussion 755-7. 2008
  9. doi Dividing the FEV1 into its component parts
    Peter T Macklem
    J Appl Physiol 105:392; author reply 393. 2008
  10. pmc Canada's contribution to respiratory physiology and pathophysiology
    Peter T Macklem
    McGill University Health Centre Research Institute, Montreal, Canada
    Can Respir J 14:383-92. 2007
  11. ncbi Percolation and phase transitions
    Henry E Fessler
    Am J Respir Crit Care Med 176:530-1. 2007
  12. ncbi A human model of the pathophysiology of chronic obstructive pulmonary disease
    Andrea Aliverti
    TBM Lab, Dipartimento di Bioingegneria, Politecnico di Milano, Milano, Italy
    Respirology 12:478-85. 2007
    ..This model reproduces the most important clinical features of COPD, and these arise from ventilatory pump dysfunction rather than from the lung. It also leads to hypotheses that can be tested in patients with COPD...
  13. pmc Transpleural ventilation of explanted human lungs
    Cliff K Choong
    Hospital of the University of Pennsylvania, 3400 Spruce St, 6 Silverstein, Philadelphia, Pennsylvania 19104, USA
    Thorax 62:623-30. 2007
    ..The hypothesis that ventilation of emphysematous lungs would be enhanced by communication with the parenchyma through holes in the pleural surface was tested...
  14. ncbi Effects of rapid saline infusion on lung mechanics and airway responsiveness in humans
    Riccardo Pellegrino
    Fisiopatoloia Respiratoria, Azienda Ospedaliera S Croce e Carle, Cuneo
    J Appl Physiol (1985) 95:728-34. 2003
    ..It is speculated that it was likely the result of airway wall edema encroaching on the bronchial lumen...
  15. ncbi Determinants of exercise performance in normal men with externally imposed expiratory flow limitation
    Iacopo Iandelli
    Fondazione Don Gnocchi, I 50020 Pozzolatico, Italy
    J Appl Physiol 92:1943-52. 2002
    ..3% of the variance in DeltaBorg. DeltaW(di) added 12.5%. We conclude that high expiratory pressures cause severe dyspnea and the possibility of adverse circulatory events, both of which would impair exercise performance...