Eric Massé

Summary

Country: Canada

Publications

  1. ncbi request reprint Small RNAs controlling iron metabolism
    Eric Massé
    Universite de Sherbrooke, Departement de Biochimie, 3001 12e Avenue, Sherbrooke, Quebec J1H 5N4, Canada
    Curr Opin Microbiol 10:140-5. 2007
  2. ncbi request reprint Ironing out the problem: new mechanisms of iron homeostasis
    Eric Massé
    Universite de Sherbrooke, Departement de Biochimie, Quebec, Canada
    Trends Biochem Sci 30:462-8. 2005
  3. pmc Effect of RyhB small RNA on global iron use in Escherichia coli
    Eric Massé
    Laboratory of Molecular Biology, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, USA
    J Bacteriol 187:6962-71. 2005
  4. pmc Coupled degradation of a small regulatory RNA and its mRNA targets in Escherichia coli
    Eric Massé
    Laboratory of Molecular Biology, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892, USA
    Genes Dev 17:2374-83. 2003
  5. ncbi request reprint Regulatory roles for small RNAs in bacteria
    Eric Massé
    Laboratory of Molecular Biology, National Cancer Institute, Bethesda, MD 20892, USA
    Curr Opin Microbiol 6:120-4. 2003
  6. pmc Dual-acting riboswitch control of translation initiation and mRNA decay
    Marie Pier Caron
    RNA Group, Department of Biology, Faculty of Science, Universite de Sherbrooke, Sherbrooke, QC, Canada J1K 2R1
    Proc Natl Acad Sci U S A 109:E3444-53. 2012
  7. pmc A small RNA promotes siderophore production through transcriptional and metabolic remodeling
    Hubert Salvail
    Department of Biochemistry, University of Sherbrooke, Sherbrooke, Quebec, QC, Canada
    Proc Natl Acad Sci U S A 107:15223-8. 2010
  8. pmc Small RNA-induced differential degradation of the polycistronic mRNA iscRSUA
    Guillaume Desnoyers
    Departement de Biochimie, Groupe ARN, Universite de Sherbrooke, Sherbrooke, Quebec, Canada
    EMBO J 28:1551-61. 2009
  9. pmc Small RNA-induced mRNA degradation achieved through both translation block and activated cleavage
    Karine Prévost
    Department of Biochemistry, RNA Group, University of Sherbrooke, Sherbrooke, Quebec J1H 5N4, Canada
    Genes Dev 25:385-96. 2011
  10. pmc A small RNA regulates the expression of genes involved in iron metabolism in Escherichia coli
    Eric Massé
    Laboratory of Molecular Biology, National Cancer Institute, Building 37, Room 5132, National Institutes of Health, Bethesda, MD 20892, USA
    Proc Natl Acad Sci U S A 99:4620-5. 2002

Collaborators

  • Susan Gottesman
  • Francois Lepine
  • James Imlay
  • Szabolcs Semsey
  • Jing Wang
  • Joseph T Wade
  • Carin K Vanderpool
  • David Lalaouna
  • Guillaume Desnoyers
  • Hubert Salvail
  • Karine Prévost
  • Julie Anna M Benjamin
  • Marie Claude Carrier
  • Marie Pier Caron
  • Laurène Bastet
  • Daniel A Lafontaine
  • Jean François Jacques
  • Audrey Morissette
  • Gaëlle Porcheron
  • Maxime Simoneau-Roy
  • Mélissa Caza
  • Charles M Dozois
  • Jean François Lemay
  • Alex Eyraud
  • Jean Simon Brouard
  • France Daigle
  • Rima Habib
  • Sébastien Houle
  • Justine Bélanger
  • Marie Pier Bouchard
  • Daniel Lafontaine
  • Antony Lussier
  • Benoit Heppell
  • Patrick St-Pierre
  • François Lavoie
  • Simon Blouin
  • Audrey Dubé
  • Martha Eugènia Sequeira Mendieta
  • Pascale Lanthier-Bourbonnais
  • Jason Michael Sobota
  • Emilie Phaneuf
  • Soojin Jang
  • Maxime Desmarais

Detail Information

Publications31

  1. ncbi request reprint Small RNAs controlling iron metabolism
    Eric Massé
    Universite de Sherbrooke, Departement de Biochimie, 3001 12e Avenue, Sherbrooke, Quebec J1H 5N4, Canada
    Curr Opin Microbiol 10:140-5. 2007
    ....
  2. ncbi request reprint Ironing out the problem: new mechanisms of iron homeostasis
    Eric Massé
    Universite de Sherbrooke, Departement de Biochimie, Quebec, Canada
    Trends Biochem Sci 30:462-8. 2005
    ..The common characteristics of these three different organisms suggest a novel mechanism of iron homeostasis...
  3. pmc Effect of RyhB small RNA on global iron use in Escherichia coli
    Eric Massé
    Laboratory of Molecular Biology, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, USA
    J Bacteriol 187:6962-71. 2005
    ..Our results demonstrate the broad effects of a single noncoding RNA on iron homeostasis...
  4. pmc Coupled degradation of a small regulatory RNA and its mRNA targets in Escherichia coli
    Eric Massé
    Laboratory of Molecular Biology, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892, USA
    Genes Dev 17:2374-83. 2003
    ..Thus, this large class of regulatory RNAs share an unexpected intrinsic mechanism for shutting off their action...
  5. ncbi request reprint Regulatory roles for small RNAs in bacteria
    Eric Massé
    Laboratory of Molecular Biology, National Cancer Institute, Bethesda, MD 20892, USA
    Curr Opin Microbiol 6:120-4. 2003
    ..Small RNAs can both positively and negatively regulate translation, can simultaneously regulate multiple mRNA targets, and can change the pattern of polarity within an operon...
  6. pmc Dual-acting riboswitch control of translation initiation and mRNA decay
    Marie Pier Caron
    RNA Group, Department of Biology, Faculty of Science, Universite de Sherbrooke, Sherbrooke, QC, Canada J1K 2R1
    Proc Natl Acad Sci U S A 109:E3444-53. 2012
    ..The riboswitch control of RNase E cleavage activity is an example of a mechanism by which metabolite sensing is used to regulate gene expression of single genes or even large polycistronic mRNAs as a function of environmental changes...
  7. pmc A small RNA promotes siderophore production through transcriptional and metabolic remodeling
    Hubert Salvail
    Department of Biochemistry, University of Sherbrooke, Sherbrooke, Quebec, QC, Canada
    Proc Natl Acad Sci U S A 107:15223-8. 2010
    ..Thus, RyhB plays an essential role in siderophore production and may modulate bacterial virulence through optimization of siderophore production...
  8. pmc Small RNA-induced differential degradation of the polycistronic mRNA iscRSUA
    Guillaume Desnoyers
    Departement de Biochimie, Groupe ARN, Universite de Sherbrooke, Sherbrooke, Quebec, Canada
    EMBO J 28:1551-61. 2009
    ..This novel regulation shows how sRNAs and mRNA structures can work together to modulate the transcriptional response to a specific stress...
  9. pmc Small RNA-induced mRNA degradation achieved through both translation block and activated cleavage
    Karine Prévost
    Department of Biochemistry, RNA Group, University of Sherbrooke, Sherbrooke, Quebec J1H 5N4, Canada
    Genes Dev 25:385-96. 2011
    ..Thus, beyond translation initiation block, sRNA-induced mRNA cleavage requires several unexpected steps, many of which are determined by structural features of the target mRNA...
  10. pmc A small RNA regulates the expression of genes involved in iron metabolism in Escherichia coli
    Eric Massé
    Laboratory of Molecular Biology, National Cancer Institute, Building 37, Room 5132, National Institutes of Health, Bethesda, MD 20892, USA
    Proc Natl Acad Sci U S A 99:4620-5. 2002
    ....
  11. pmc Antagonistic functions between the RNA chaperone Hfq and an sRNA regulate sensitivity to the antibiotic colicin
    Hubert Salvail
    Department of Biochemistry, RNA Group, University of Sherbrooke, Sherbrooke, Quebec, Canada
    EMBO J 32:2764-78. 2013
    ..Altogether, these results indicate that Fur and RyhB modulate an unexpected feed-forward loop mechanism related to iron physiology and colicin sensitivity. ..
  12. ncbi request reprint RyhB small RNA modulates the free intracellular iron pool and is essential for normal growth during iron limitation in Escherichia coli
    Jean François Jacques
    Departement de Biochimie, Faculte de Medecine et des Sciences de la Sante, Groupe ARN Université de Sherbrooke, Sherbrooke, Quebec, Canada
    Mol Microbiol 62:1181-90. 2006
    ..Overall, our data demonstrate that, by regulating synthesis of nonessential iron-using proteins, the small RNA RyhB ensures that the iron is directed towards the iron-requiring enzymes that are indispensable...
  13. pmc The small RNA RyhB contributes to siderophore production and virulence of uropathogenic Escherichia coli
    Gaëlle Porcheron
    INRS Institut Armand Frappier, Laval, Quebec, Canada
    Infect Immun 82:5056-68. 2014
    ..Our results thus demonstrate that the sRNA RyhB is involved in production of iron acquisition systems and colonization of the urinary tract by pathogenic E. coli. ..
  14. ncbi request reprint The small RNA RyhB activates the translation of shiA mRNA encoding a permease of shikimate, a compound involved in siderophore synthesis
    Karine Prévost
    Departement de Biochimie, Groupe ARN, Universite de Sherbrooke, Sherbrooke, Quebec, Canada
    Mol Microbiol 64:1260-73. 2007
    ..This is demonstrated by growth assays in which shikimate or the siderophore enterochelin correct the growth defect observed for a ryhB mutant in iron-limited media...
  15. ncbi request reprint Small RNA-mediated regulation at the level of transcript stability
    Marie Pier Caron
    Department of Biochemistry, University of Sherbrooke, RNA Group, Sherbrooke, QC, Canada
    RNA Biol 7:140-4. 2010
    ..While the outcome resembles the RNAi silencing described in eukaryotes, the mechanism of bacterial sRNAs differs fundamentally. These sRNAs are the subject of intensive studies, which makes them the best characterized sRNAs to date...
  16. doi request reprint Regulating iron storage and metabolism with RNA: an overview of posttranscriptional controls of intracellular iron homeostasis
    Hubert Salvail
    RNA Group, Department of Biochemistry, University of Sherbrooke, Sherbrooke, Quebec, Canada
    Wiley Interdiscip Rev RNA 3:26-36. 2012
    ..These recent findings have shed light on the complexity of iron homeostasis...
  17. doi request reprint Dealing with oxidative stress and iron starvation in microorganisms: an overview
    Julie Anna M Benjamin
    Department of Biochemistry, RNA Group, University of Sherbrooke, Sherbrooke, QC J1H 5N4, Canada
    Can J Physiol Pharmacol 88:264-72. 2010
    ..An overview of the different strategies used by bacteria to cope with iron starvation and oxidative stress is presented here...
  18. pmc Comparative study between transcriptionally- and translationally-acting adenine riboswitches reveals key differences in riboswitch regulatory mechanisms
    Jean François Lemay
    Groupe ARN RNA Group, Departement de Biologie, Faculte des Sciences, Universite de Sherbrooke, Sherbrooke, Quebec, Canada
    PLoS Genet 7:e1001278. 2011
    ..Our results suggest that the nature of gene regulation control, that is transcription or translation, may have a high importance in riboswitch regulatory mechanisms...
  19. doi request reprint New insights into small RNA-dependent translational regulation in prokaryotes
    Guillaume Desnoyers
    University of Sherbrooke, Faculty of Medicine and Health Sciences, Department of Biochemistry, RNA Group, 3201 Jean Mignault Street, Sherbrooke, QC, J1E 4K8, Canada
    Trends Genet 29:92-8. 2013
    ..These new mechanisms broaden current perspectives of sRNA pairing sites on mRNA targets and demonstrate how the interplay between sRNAs, mRNA structures, and protein partners can contribute to post-transcriptional regulation...
  20. doi request reprint Regulatory RNAs and target mRNA decay in prokaryotes
    David Lalaouna
    Department of Biochemistry, Universite de Sherbrooke, Sherbrooke, Quebec, Canada
    Biochim Biophys Acta 1829:742-7. 2013
    ..These new mechanisms illustrate how sRNAs and mRNA structures, including riboswitches, act cooperatively with protein partners to initiate the decay of mRNAs. This article is part of a Special Issue entitled: RNA Decay mechanisms...
  21. doi request reprint DsrA regulatory RNA represses both hns and rbsD mRNAs through distinct mechanisms in Escherichia coli
    David Lalaouna
    Universite de Sherbrooke, Faculty of Medicine and Health Sciences, Department of Biochemistry, RNA Group, Sherbrooke, Quebec, Canada
    Mol Microbiol 98:357-69. 2015
    ..Surprisingly, DsrA base pairs far downstream of rbsD start codon and induces rapid degradation of the transcript. Thus, our study enables us to draw an extended DsrA targetome. ..
  22. pmc Noncanonical repression of translation initiation through small RNA recruitment of the RNA chaperone Hfq
    Guillaume Desnoyers
    RNA Group, Department of Biochemistry, University of Sherbrooke, Sherbrooke, Quebec J1H 5N4, Canada
    Genes Dev 26:726-39. 2012
    ..Contrary to the canonical model of sRNA regulation, this suggests a new mechanism where Hfq is directly involved in the translational repression of the target mRNA and where the sRNA acts only as a recruitment factor...
  23. doi request reprint New insights into riboswitch regulation mechanisms
    Laurène Bastet
    Departement de Biologie, Faculte des Sciences, Groupe ARN RNA Group, Universite de Sherbrooke, Sherbrooke, Quebec, Canada
    Mol Microbiol 80:1148-54. 2011
    ..This review focuses on recent discoveries in riboswitch regulatory mechanisms as well as current outstanding challenges...
  24. pmc A game of tag: MAPS catches up on RNA interactomes
    Marie Claude Carrier
    a Department of Biochemistry, RNA Group, Universite de Sherbrooke, Sherbrooke, Quebec, Canada
    RNA Biol 13:473-6. 2016
    ..The impressive potential of MAPS has been supported by a number of reports. Here, we concisely overview RNA-tagging history that preceded the development of the MAPS assay and expose the range of possible uses of this technology. ..
  25. doi request reprint Identification of unknown RNA partners using MAPS
    David Lalaouna
    Department of Biochemistry, RNA Group, Universite de Sherbrooke, Sherbrooke, Québec J1E 4K8, Canada
    Methods . 2016
    ..Here, we clearly report all improvements and adjustments made to MAPS technology since it was originally reported...
  26. pmc Every little piece counts: the many faces of tRNA transcripts
    David Lalaouna
    a Department of Biochemistry RNA Group Université de Sherbrooke Sherbrooke, Quebec, Canada
    Transcription 6:74-7. 2015
    ..Here, we succinctly review the diversity and functions of RNAs deriving from tRNA loci. ..
  27. doi request reprint Activity of small RNAs on the stability of targeted mRNAs in vivo
    Guillaume Desnoyers
    Department of Biochemistry, University of Sherbrooke, Sherbrooke, QC, Canada
    Methods Mol Biol 905:245-55. 2012
    ..We also describe how to identify a sRNA-induced initial cleavage site on a target mRNA. This protocol can be used for any sRNAs and their target mRNAs...
  28. ncbi request reprint Remote control of mRNA cleavage by a small RNA
    Julie Anna M Benjamin
    University of Sherbrooke Sherbrooke, Quebec, Canada
    Cell Cycle 10:1706-7. 2011
    ..Comment on: Prévost K, et al. Genes Dev 2011; 25:385-96...
  29. doi request reprint The spectrum of activity of the small RNA DsrA: not so narrow after all
    David Lalaouna
    RNA Group, Department of Biochemistry, Universite de Sherbrooke, 3201 Jean Mignault Street, Sherbrooke, QC, J1E 4K8, Canada
    Curr Genet 62:261-4. 2016
    ..In this review, we summarize new insights in DsrA-mediated regulation and emphasize the versatility of DsrA modes of action. ..
  30. pmc The iron-sensing aconitase B binds its own mRNA to prevent sRNA-induced mRNA cleavage
    Julie Anna M Benjamin
    Department of Biochemistry, RNA Group, University of Sherbrooke, 3201 Jean Mignault Street, Sherbrooke, Québec J1E 4K8, Canada
    Nucleic Acids Res 42:10023-36. 2014
    ..This previously uncharacterized regulation suggests an intricate post-transcriptional mechanism that represses protein expression while insuring mRNA stability. ..
  31. doi request reprint A 3' external transcribed spacer in a tRNA transcript acts as a sponge for small RNAs to prevent transcriptional noise
    David Lalaouna
    Department of Biochemistry, RNA Group, Universite de Sherbrooke, Sherbrooke, Quebec, J1E 4K8, Canada
    Mol Cell 58:393-405. 2015
    ..Additional data showing RybB and MicF sRNAs are co-purified with ITS(metZ-metW) and ITS(metW-metV) strongly suggest a wide distribution of this phenomenon...