Jean Théberge

Summary

Affiliation: Lawson Health Research Institute
Country: Canada

Publications

  1. doi request reprint Perfusion magnetic resonance imaging in psychiatry
    Jean Théberge
    Department of Diagnostic Imaging, St Joseph s Health Care, 268 Grosvenor Street, London, Ontario, Canada
    Top Magn Reson Imaging 19:111-30. 2008
  2. ncbi request reprint Longitudinal grey-matter and glutamatergic losses in first-episode schizophrenia
    Jean Théberge
    St Joseph s Health Care, Nuclear Medicine and MR, Room B5 233, 268 Grosvenor Street, London, Ontario N6A 4V2, Canada
    Br J Psychiatry 191:325-34. 2007
  3. ncbi request reprint Glutamate and glutamine in the anterior cingulate and thalamus of medicated patients with chronic schizophrenia and healthy comparison subjects measured with 4.0-T proton MRS
    Jean Théberge
    Department of Nuclear Medicine and Magnetic Resonance, St Joseph s Health Care, London, Ont, Canada
    Am J Psychiatry 160:2231-3. 2003
  4. doi request reprint Grey matter and social functioning correlates of glutamatergic metabolite loss in schizophrenia
    Naoko Aoyama
    Department of Medical Biophysics, University of Western Ontario, London, Ontario, Canada
    Br J Psychiatry 198:448-56. 2011
  5. ncbi request reprint Glutamate and glutamine measured with 4.0 T proton MRS in never-treated patients with schizophrenia and healthy volunteers
    Jean Théberge
    Department of Nuclear Medicine and Magnetic Resonance, St Joseph s Health Care, London, ON, Canada
    Am J Psychiatry 159:1944-6. 2002
  6. ncbi request reprint A 4.0-T fMRI study of brain connectivity during word fluency in first-episode schizophrenia
    Kristine Boksman
    University of Western Ontario, 1151 Richmond Street, London, Ontario, Canada N6A 5B8
    Schizophr Res 75:247-63. 2005
  7. ncbi request reprint Duration of untreated psychosis vs. N-acetylaspartate and choline in first episode schizophrenia: a 1H magnetic resonance spectroscopy study at 4.0 Tesla
    Jean Théberge
    Department of Medical Biophysics, University of Western Ontario, London, ON, Canada
    Psychiatry Res 131:107-14. 2004
  8. ncbi request reprint Comparative study of proton and phosphorus magnetic resonance spectroscopy in schizophrenia at 4 Tesla
    Jean Théberge
    Department of Medical Biophysics, University of Western Ontario, London, Ontario, Canada
    Psychiatry Res 132:33-9. 2004
  9. doi request reprint Evidence for a dose-dependent effect of pulsed magnetic fields on pain processing
    John A Robertson
    Imaging Program, Lawson Health Research Institute, London, ON, Canada
    Neurosci Lett 482:160-2. 2010
  10. doi request reprint The neurobiology of emotion regulation in posttraumatic stress disorder: Amygdala downregulation via real-time fMRI neurofeedback
    Andrew A Nicholson
    Department of Neuroscience, Western University, London, Ontario, Canada
    Hum Brain Mapp 38:541-560. 2017

Collaborators

Detail Information

Publications25

  1. doi request reprint Perfusion magnetic resonance imaging in psychiatry
    Jean Théberge
    Department of Diagnostic Imaging, St Joseph s Health Care, 268 Grosvenor Street, London, Ontario, Canada
    Top Magn Reson Imaging 19:111-30. 2008
    ..An outlook of necessary steps to bring perfusion MRI into the realm of clinical psychiatry as a diagnostic tool is brought forth. Opportunities for research in unexplored disorders and with higher field strengths are briefly examined...
  2. ncbi request reprint Longitudinal grey-matter and glutamatergic losses in first-episode schizophrenia
    Jean Théberge
    St Joseph s Health Care, Nuclear Medicine and MR, Room B5 233, 268 Grosvenor Street, London, Ontario N6A 4V2, Canada
    Br J Psychiatry 191:325-34. 2007
    ..Progressive volumetric changes in the brains of people with schizophrenia have been attributed to a number of factors...
  3. ncbi request reprint Glutamate and glutamine in the anterior cingulate and thalamus of medicated patients with chronic schizophrenia and healthy comparison subjects measured with 4.0-T proton MRS
    Jean Théberge
    Department of Nuclear Medicine and Magnetic Resonance, St Joseph s Health Care, London, Ont, Canada
    Am J Psychiatry 160:2231-3. 2003
    ..This in vivo (1)H magnetic resonance spectroscopy study examined levels of glutamate, glutamine, and N-acetylaspartate in medicated patients with chronic schizophrenia...
  4. doi request reprint Grey matter and social functioning correlates of glutamatergic metabolite loss in schizophrenia
    Naoko Aoyama
    Department of Medical Biophysics, University of Western Ontario, London, Ontario, Canada
    Br J Psychiatry 198:448-56. 2011
    ..Thalamic glutamine loss and grey matter reduction suggest neurodegeneration in first-episode schizophrenia, but the duration is unknown...
  5. ncbi request reprint Glutamate and glutamine measured with 4.0 T proton MRS in never-treated patients with schizophrenia and healthy volunteers
    Jean Théberge
    Department of Nuclear Medicine and Magnetic Resonance, St Joseph s Health Care, London, ON, Canada
    Am J Psychiatry 159:1944-6. 2002
    ..This in vivo (1)H magnetic resonance spectroscopy study examined levels of glutamate, glutamine, and N-acetylaspartate in patients experiencing their first episode of schizophrenia...
  6. ncbi request reprint A 4.0-T fMRI study of brain connectivity during word fluency in first-episode schizophrenia
    Kristine Boksman
    University of Western Ontario, 1151 Richmond Street, London, Ontario, Canada N6A 5B8
    Schizophr Res 75:247-63. 2005
    ....
  7. ncbi request reprint Duration of untreated psychosis vs. N-acetylaspartate and choline in first episode schizophrenia: a 1H magnetic resonance spectroscopy study at 4.0 Tesla
    Jean Théberge
    Department of Medical Biophysics, University of Western Ontario, London, ON, Canada
    Psychiatry Res 131:107-14. 2004
    ..Increased choline is associated with longer duration of untreated psychosis and could indicate that psychosis-related membrane alterations precede the appearance of NAA reductions observed by studies of chronic schizophrenia...
  8. ncbi request reprint Comparative study of proton and phosphorus magnetic resonance spectroscopy in schizophrenia at 4 Tesla
    Jean Théberge
    Department of Medical Biophysics, University of Western Ontario, London, Ontario, Canada
    Psychiatry Res 132:33-9. 2004
    ..The negative correlation between N-acetylaspartate and glycerophosphocholine may reflect the presence of neurodegeneration...
  9. doi request reprint Evidence for a dose-dependent effect of pulsed magnetic fields on pain processing
    John A Robertson
    Imaging Program, Lawson Health Research Institute, London, ON, Canada
    Neurosci Lett 482:160-2. 2010
    ....
  10. doi request reprint The neurobiology of emotion regulation in posttraumatic stress disorder: Amygdala downregulation via real-time fMRI neurofeedback
    Andrew A Nicholson
    Department of Neuroscience, Western University, London, Ontario, Canada
    Hum Brain Mapp 38:541-560. 2017
    ..Hum Brain Mapp 38:541-560, 2017. © 2016 Wiley Periodicals, Inc...
  11. doi request reprint Unique insula subregion resting-state functional connectivity with amygdala complexes in posttraumatic stress disorder and its dissociative subtype
    Andrew A Nicholson
    Department of Neuroscience, Western University, London, ON, Canada
    Psychiatry Res 250:61-72. 2016
    ..This study is an important first step in elucidating patterns of neural connectivity associated with unique symptoms of arousal/interoception, emotional processing, and awareness of bodily states, in PTSD and its dissociative subtype. ..
  12. pmc Alpha oscillation neurofeedback modulates amygdala complex connectivity and arousal in posttraumatic stress disorder
    Andrew A Nicholson
    Department of Neuroscience, Western University, London, ON, Canada
    Neuroimage Clin 12:506-516. 2016
    ....
  13. pmc Increased glutamate levels observed upon functional activation in the anterior cingulate cortex using the Stroop Task and functional spectroscopy
    Reggie Taylor
    Departments of aMedical Biophysics bPsychiatry cPsychology dNeuroscience eAnatomy and Cell Biology, University of Western Ontario fLawson Health Research Institute, London, Ontario, Canada
    Neuroreport 26:107-12. 2015
    ..This exploratory study is the first to demonstrate functional magnetic resonance spectroscopy in the anterior cingulate with a cognitive task using a 7 T MRI. ..
  14. pmc Aberrant Functional Connectivity of the Amygdala Complexes in PTSD during Conscious and Subconscious Processing of Trauma-Related Stimuli
    Daniela Rabellino
    Department of Psychiatry, University of Western Ontario, London, ON, Canada
    PLoS ONE 11:e0163097. 2016
    ..These findings demonstrate alterations in amygdala subregion functional connectivity in PTSD and highlight the disruption of the innate alarm network during both conscious and subconscious trauma processing in this disorder. ..
  15. doi request reprint Description and assessment of a registration-based approach to include bones for attenuation correction of whole-body PET/MRI
    Harry R Marshall
    The Lawson Health Research Institute, Imaging Program, 268 Grosvenor Street, London, Ontario N6A 4V2, Canada
    Med Phys 40:082509. 2013
    ..In this work, the authors build on this segmentation approach by adding bones using a registration technique and assessing its performance on human PET images...
  16. doi request reprint Brain activation to favorite music in healthy controls and depressed patients
    Elizabeth A Osuch
    Department of Psychiatry, University of Western Ontario, London, ON N6A3H8, Canada
    Neuroreport 20:1204-8. 2009
    ..This paradigm activated neurocircuitry of reward processing and showed clinically meaningful alterations in depression...
  17. pmc The Dissociative Subtype of Posttraumatic Stress Disorder: Unique Resting-State Functional Connectivity of Basolateral and Centromedial Amygdala Complexes
    Andrew A Nicholson
    Schulich School of Medicine and Dentistry, Western University, London, Ontario, Canada
    Neuropsychopharmacology 40:2317-26. 2015
    ..Differences in amygdala complex connectivity to specific brain regions parallel the unique symptom profiles of the PTSD subgroups and point towards unique biological markers of the dissociative subtype of PTSD. ..
  18. doi request reprint Glutamatergic metabolite correlations with neuropsychological tests in first episode schizophrenia
    Kara Dempster
    Department of Psychiatry, Western University, London, Ontario, Canada Electronic address
    Psychiatry Res 233:180-5. 2015
    ....
  19. pmc Neuroimaging self-esteem: a fMRI study of individual differences in women
    Paul A Frewen
    Department of Psychiatry, Western University, London, ON, Canada
    Soc Cogn Affect Neurosci 8:546-55. 2013
    ..Results are discussed as they relate to a social cognitive and affective neuroscience view of self-esteem...
  20. pmc Spontaneous low-frequency fluctuations in the BOLD signal in schizophrenic patients: anomalies in the default network
    Robyn L Bluhm
    Department of Psychiatry, Schulich School of Medicine and Dentistry, University of Western Ontario, London, Canada
    Schizophr Bull 33:1004-12. 2007
    ..Because these data suggest significant abnormalities in resting-state neural networks in schizophrenia, further investigations of spontaneous slow fluctuations of the BOLD signal seem warranted in this population...
  21. doi request reprint Correlation of brain default mode network activation with bipolarity index in youth with mood disorders
    Kristen A Ford
    University of Western Ontario, Schulich School of Medicine and Dentistry, Department of Psychiatry, London, Ontario, Canada
    J Affect Disord 150:1174-8. 2013
    ..Here we have utilized fMRI and a measure of trait bipolarity to examine resting-state functional connectivity of brain activation in the default mode network in youth with MDD and BD to isolate trait-specific patterns...
  22. pmc Mind over chatter: plastic up-regulation of the fMRI salience network directly after EEG neurofeedback
    Tomas Ros
    Department of Psychiatry, University of Western Ontario, London, Ontario, Canada
    Neuroimage 65:324-35. 2013
    ....
  23. ncbi request reprint Implementation issues of multivoxel STEAM-localized 1H spectroscopy
    Jean Théberge
    Department of Nuclear Medicine and Magnetic Resonance, St Joseph s Health Care, 268 Grosvenor Street, London, Ontario N6A 4V2, Canada
    Magn Reson Med 53:713-8. 2005
    ..A two-voxel STEAM approach produces phantom and in vivo data quality comparable to single-voxel STEAM in practically half the time. Quantification precision and accuracy are preserved in phantoms and in vivo...
  24. doi request reprint Variable lung density consideration in attenuation correction of whole-body PET/MRI
    Harry R Marshall
    The Lawson Health Research Institute, Imaging Program, London, Ontario, Canada
    J Nucl Med 53:977-84. 2012
    ..In this work, a technique to incorporate patient-specific lung density information into MRI-based attenuation maps is developed and compared with an approach that assumes uniform lung density...
  25. pmc Low-frequency pulsed electromagnetic field exposure can alter neuroprocessing in humans
    John A Robertson
    Imaging Program, Lawson Health Research Institute, 268 Grosvenor Street, London, Ontario, Canada, N6A 4V2
    J R Soc Interface 7:467-73. 2010
    ..Magnetoreception may be more common than presently thought...