Andre Lacroix

Summary

Country: Canada

Publications

  1. doi Approach to the patient with adrenocortical carcinoma
    Andre Lacroix
    Division of Endocrinology, Department of Medicine, Centre de recherche du Centre hospitalier de l Université de Montréal CRCHUM, Universite de Montreal, Montreal, Quebec, Canada
    J Clin Endocrinol Metab 95:4812-22. 2010
  2. ncbi Bilateral adrenal Cushing's syndrome: macronodular adrenal hyperplasia and primary pigmented nodular adrenocortical disease
    Andre Lacroix
    Department of Medicine, Hôtel Dieu du Centre hospitalier de l Université de Montréal, 3840 Saint Urbain street, Montreal, Quebec H2W 1T8, Canada
    Endocrinol Metab Clin North Am 34:441-58, x. 2005
  3. doi Cushing's syndrome
    Andre Lacroix
    Division of Endocrinology, Department of Medicine and Research Center, Centre Hospitalier de l Universite de Montreal CHUM, Montreal, QC, Canada Electronic address
    Lancet 386:913-27. 2015
  4. ncbi International concerted action on collaboration in telemedicine: recommendations of the G-8 Global Healthcare Applications Subproject-4
    Andre Lacroix
    Telemedicine Unit, Hôtel Dieu du Centre hospitalier de l Université de Montréal, Montreal, Quebec, Canada
    Telemed J E Health 8:149-57. 2002
  5. ncbi Cushing's syndrome variants secondary to aberrant hormone receptors
    Andre Lacroix
    Laboratories of Endocrine Pathophysiology, Cellular Biology of Hypertension, and Molecular Medicine, Department of Medicine, Hôtel Dieu du Centre hospitalier de l Université de Montréal CHUM, Montreal H2W 1T8, Canada
    Trends Endocrinol Metab 15:375-82. 2004
  6. doi ACTH-independent macronodular adrenal hyperplasia
    Andre Lacroix
    Department of Medicine, Division of Endocrinology, Centre Hospitalier de l Universite de Montreal, Hotel Dieu du CHUM, Montreal, Quebec, Canada
    Best Pract Res Clin Endocrinol Metab 23:245-59. 2009
  7. doi Aberrant G-protein coupled receptor expression in relation to adrenocortical overfunction
    Andre Lacroix
    Division of Endocrinology, Department of Medicine, Centre de recherche du Centre Hospitalier de l Universite de Montreal, Universite de Montreal, Montreal, QC, Canada
    Clin Endocrinol (Oxf) 73:1-15. 2010
  8. ncbi [Illicit hormone receptors in adrenal Cushing's syndrome]
    A Lacroix
    Service d Endocrinologie et Département de Médecine, Centre de Recherche, Hôtel Dieu du Centre hospitalier de l Université de Montréal, CHUM 3840, rue Saint Urbain, Montréal Québec H2W 1T8
    Ann Endocrinol (Paris) 62:185-8. 2001
  9. ncbi Ectopic and abnormal hormone receptors in adrenal Cushing's syndrome
    A Lacroix
    Department of Medicine, Research Center, H tel du Centre Hospitalier de l Université de Montréal, Quebec, Canada
    Endocr Rev 22:75-110. 2001
  10. ncbi The diversity of abnormal hormone receptors in adrenal Cushing's syndrome allows novel pharmacological therapies
    A Lacroix
    Division of Endocrinology, Department of Medicine, Research Center, Hôtel Dieu du Centre Hospitalier, Universite de Montreal, Montreal, Canada
    Braz J Med Biol Res 33:1201-9. 2000

Collaborators

Detail Information

Publications54

  1. doi Approach to the patient with adrenocortical carcinoma
    Andre Lacroix
    Division of Endocrinology, Department of Medicine, Centre de recherche du Centre hospitalier de l Université de Montréal CRCHUM, Universite de Montreal, Montreal, Quebec, Canada
    J Clin Endocrinol Metab 95:4812-22. 2010
    ..New insights in the molecular pathogenesis of ACC should allow the development of improved targeted therapies...
  2. ncbi Bilateral adrenal Cushing's syndrome: macronodular adrenal hyperplasia and primary pigmented nodular adrenocortical disease
    Andre Lacroix
    Department of Medicine, Hôtel Dieu du Centre hospitalier de l Université de Montréal, 3840 Saint Urbain street, Montreal, Quebec H2W 1T8, Canada
    Endocrinol Metab Clin North Am 34:441-58, x. 2005
    ..Additionally, it can be secondary to mutations of type 1 alpha-regulatory subunit of cAMP-dependent protein kinase A (PRKARIA). Strategies for the investigation and treatment of AIMAH and PPNAD are discussed...
  3. doi Cushing's syndrome
    Andre Lacroix
    Division of Endocrinology, Department of Medicine and Research Center, Centre Hospitalier de l Universite de Montreal CHUM, Montreal, QC, Canada Electronic address
    Lancet 386:913-27. 2015
    ..However, for patients affected by this challenging syndrome, the long-term effects and comorbidities associated with hypercortisolism need ongoing care. ..
  4. ncbi International concerted action on collaboration in telemedicine: recommendations of the G-8 Global Healthcare Applications Subproject-4
    Andre Lacroix
    Telemedicine Unit, Hôtel Dieu du Centre hospitalier de l Université de Montréal, Montreal, Quebec, Canada
    Telemed J E Health 8:149-57. 2002
    ..The 21 recommendations are presented in this report...
  5. ncbi Cushing's syndrome variants secondary to aberrant hormone receptors
    Andre Lacroix
    Laboratories of Endocrine Pathophysiology, Cellular Biology of Hypertension, and Molecular Medicine, Department of Medicine, Hôtel Dieu du Centre hospitalier de l Université de Montréal CHUM, Montreal H2W 1T8, Canada
    Trends Endocrinol Metab 15:375-82. 2004
    ..The identification of aberrant adrenal GPCRs offers the potential for novel pharmacological therapies that either suppress the endogenous ligands or block the receptor with specific antagonists...
  6. doi ACTH-independent macronodular adrenal hyperplasia
    Andre Lacroix
    Department of Medicine, Division of Endocrinology, Centre Hospitalier de l Universite de Montreal, Hotel Dieu du CHUM, Montreal, Quebec, Canada
    Best Pract Res Clin Endocrinol Metab 23:245-59. 2009
    ..The identification of aberrant receptors can offer a specific pharmacological approach to prevent progression and control abnormal steroidogenesis; alternatively, unilateral or bilateral adrenalectomy becomes the treatment of choice...
  7. doi Aberrant G-protein coupled receptor expression in relation to adrenocortical overfunction
    Andre Lacroix
    Division of Endocrinology, Department of Medicine, Centre de recherche du Centre Hospitalier de l Universite de Montreal, Universite de Montreal, Montreal, QC, Canada
    Clin Endocrinol (Oxf) 73:1-15. 2010
    ....
  8. ncbi [Illicit hormone receptors in adrenal Cushing's syndrome]
    A Lacroix
    Service d Endocrinologie et Département de Médecine, Centre de Recherche, Hôtel Dieu du Centre hospitalier de l Université de Montréal, CHUM 3840, rue Saint Urbain, Montréal Québec H2W 1T8
    Ann Endocrinol (Paris) 62:185-8. 2001
    ....
  9. ncbi Ectopic and abnormal hormone receptors in adrenal Cushing's syndrome
    A Lacroix
    Department of Medicine, Research Center, H tel du Centre Hospitalier de l Université de Montréal, Quebec, Canada
    Endocr Rev 22:75-110. 2001
    ....
  10. ncbi The diversity of abnormal hormone receptors in adrenal Cushing's syndrome allows novel pharmacological therapies
    A Lacroix
    Division of Endocrinology, Department of Medicine, Research Center, Hôtel Dieu du Centre Hospitalier, Universite de Montreal, Montreal, Canada
    Braz J Med Biol Res 33:1201-9. 2000
    ....
  11. ncbi Expression of ACTH receptor pathway genes in glucose-dependent insulinotrophic peptide (GIP)-dependent Cushing's syndrome
    Sonir R Antonini
    Laboratory of Endocrine Pathophysiology, Research Centre, Hôtel Dieu du Centre hospitalier de l Université de Montréal CHUM, Montreal, Quebec, Canada
    Clin Endocrinol (Oxf) 64:29-36. 2006
    ..We studied the expression of several genes involved in this pathway in the adrenal tissues of patients with GIP-dependent CS...
  12. doi Cooperation between cyclin E and p27(Kip1) in pituitary tumorigenesis
    Audrey Roussel-Gervais
    Laboratoire de Genetique Moleculaire, Institut de Recherches Cliniques de Montreal, 110 avenue des Pins Ouest, Montreal, Quebec, Canada H2W 1R7
    Mol Endocrinol 24:1835-45. 2010
    ..These results suggest that cyclin E up-regulation and p27(Kip1) loss-of-function act cooperatively on pituitary adenoma development...
  13. ncbi Whole genome expression profiling of glucose-dependent insulinotropic peptide (GIP)- and adrenocorticotropin-dependent adrenal hyperplasias reveals novel targets for the study of GIP-dependent Cushing's syndrome
    Antoine Lampron
    Department of Medicine, Hôtel Dieu du Centre hospitalier de l Université de Montréal, Montreal, Quebec, Canada
    J Clin Endocrinol Metab 91:3611-8. 2006
    ..Chronic adrenal stimulation by ACTH in Cushing's disease or GIP in GIP-dependent ACTH-independent macronodular adrenal hyperplasia both lead to the induction of genes implicated in adrenal proliferation and steroidogenesis...
  14. ncbi Primary pigmented nodular adrenocortical disease: paradoxical responses of cortisol secretion to dexamethasone occur in vitro and are associated with increased expression of the glucocorticoid receptor
    Isabelle Bourdeau
    Division of Endocrinology and Pathology, Hôtel Dieu du Centre Hospitalier de l Université de Montréal and Department of Biochemistry, Universite de Montreal, Montreal, Canada H2W 1T7
    J Clin Endocrinol Metab 88:3931-7. 2003
    ....
  15. ncbi Clinical and subclinical ACTH-independent macronodular adrenal hyperplasia and aberrant hormone receptors
    Stavroula Christopoulos
    Division of Endocrinology, Department of Medicine, Centre Hospitalier de l Universite de Montreal, Montreal, Canada
    Horm Res 64:119-31. 2005
    ..The identification of these receptors provides the potential for novel pharmacological therapies by suppressing the endogenous ligands or blocking the receptor with specific antagonists...
  16. ncbi Cushing's syndrome secondary to ACTH-independent macronodular adrenal hyperplasia
    Marcia Helena Soares Costa
    Division of Endocrinology, Department of Medicine, Centre hospitalierde l Université de Montréal, Montreal, Canada
    Arq Bras Endocrinol Metabol 51:1226-37. 2007
    ..The identification of these receptors creates the possibility of a specific pharmacological treatment isolated or associated with adrenalectomy...
  17. ncbi The Sp transcription factors are involved in the cellular expression of the human glucose-dependent insulinotropic polypeptide receptor gene and overexpressed in adrenals of patients with Cushing's syndrome
    Valérie Baldacchino
    Laboratory of Endocrine Pathophysiology, Department of Medicine, Centre Hospitalier de l Universite de Montreal, Quebec, Canada
    J Mol Endocrinol 35:61-71. 2005
    ..This study represents the first step in our understanding of the mechanisms involved in the regulation of the expression of the hGIP-R gene...
  18. ncbi Adrenal vein sampling in primary aldosteronism: concordance of simultaneous vs sequential sampling
    Mohamed Karji Almarzooqi
    Department of RadiologyCentre Hospitalier de l Université de Montréal CHUM, Montreal, Quebec, Canada
    Eur J Endocrinol 176:159-167. 2017
    ..This study aimed to evaluate the concordance of sequential and simultaneous AVS methods...
  19. ncbi Adrenal venous sampling in primary aldosteronism: multinomial regression modeling to detect aldosterone secretion lateralization when right adrenal sampling is missing
    Camille Durivage
    aDepartment of Radiology, Centre hospitalier de l Université de Montréal CHUM bCentre de recherche, CHUM CRCHUM cDepartment of Mathematics and Statistic, University of Montreal dDivision of Endocrinology, Department of Medicine, Centre Hospitalier de l Universite de Montreal CHUM, Montreal, Quebec, Canada
    J Hypertens . 2016
    ..We aimed to assess multinomial regression modeling (MRM) of peripheral and left adrenal vein samplings to detect lateralization of aldosterone secretion when the right AVS is missing...
  20. doi Basal and Post-ACTH Aldosterone and Its Ratios Are Useful During Adrenal Vein Sampling in Primary Aldosteronism
    Nada El Ghorayeb
    Department of Medicine N E G, T L M, I B, P S Z, A L and Department of Radiology J P M, E T, Division of Endocrinology, Centre de recherche du centre hospitalier de l Université de Montréal CHUM, Universite de Montreal, Quebec, H2W 1T8, Canada
    J Clin Endocrinol Metab 101:1826-35. 2016
    ..ACTH improves selectivity, but can modify lateralization. Basal and post-ACTH ratios are important for surgical indication. Basal aldosterone contralateral suppression predicts residual hyperplasia and post-operative outcomes. ..
  21. ncbi Adrenocorticotropic hormone-independent Cushing's syndrome
    Isabelle Bourdeau
    Division of Endocrinology, Department of Medicine and Research Center, Centre Hospitalier de l Universite de Montreal CHUM, Montreal, Quebec, Canada
    Curr Opin Endocrinol Diabetes Obes 14:219-25. 2007
    ..Primary pigmented nodular adrenocortical disease can be found either alone or in the context of Carney complex, a multiple endocrine neoplasia syndrome...
  22. doi ARMC5 mutations in a large French-Canadian family with cortisol-secreting β-adrenergic/vasopressin responsive bilateral macronodular adrenal hyperplasia
    Isabelle Bourdeau
    Division of EndocrinologyDepartment of MedicineDivision of Medical GeneticsDepartment of Medicine, Centre de recherche du Centre hospitalier de l Université de Montréal CRCHUM, Montreal, Quebec, CanadaDepartment of PathologyCHUM, Montreal, Quebec, CanadaDepartment of PediatricsCentre de Recherche CHU Sainte Justine, Universite de Montreal, Montreal, Quebec, CanadaUnidade de SuprarrenalDisciplina de Endocrinologia e Metabologia, Laboratório de Hormônios e Genética Molecular LIM42, Hospital das Clinicas, Faculdade de Medicina da Universidade de Sao Paulo, Sao Paulo, Brazil Division of EndocrinologyDepartment of MedicineDivision of Medical GeneticsDepartment of Medicine, Centre de recherche du Centre hospitalier de l Université de Montréal CRCHUM, Montreal, Quebec, CanadaDepartment of PathologyCHUM, Montreal, Quebec, CanadaDepartment of PediatricsCentre de Recherche CHU Sainte Justine, Universite de Montreal, Montreal, Quebec, CanadaUnidade de SuprarrenalDisciplina de Endocrinologia e Metabologia, Laboratório de Hormônios e Genética Molecular LIM42, Hospital das Clinicas, Faculdade de Medicina da Universidade de Sao Paulo, Sao Paulo, Brazil
    Eur J Endocrinol 174:85-96. 2016
    ..Recent studies identified that ARMC5 mutations occur frequently in BMAH, but the relation between ARMC5 mutation and the expression of aberrant G-protein-coupled receptor has not been examined in detail yet...
  23. doi Adrenal Vein Sampling in Primary Aldosteronism: Sensitivity and Specificity of Basal Adrenal Vein to Peripheral Vein Cortisol and Aldosterone Ratios to Confirm Catheterization of the Adrenal Vein
    Jean Philippe Mailhot
    From the Division of Interventional Radiology, Department of Radiology J P M, M T, G S, M F G, P G, V L O, E T, and Division of Endocrinology, Department of Medicine P S Z, I B, A L, Centre Hospitalier de l Universite de Montreal CHUM, 3840 rue Saint Urbain, Montreal, QC, Canada H2W 1T8 and Centre de Recherche du CHUM CRCHUM, Montreal, QC, Canada G S, M L
    Radiology 277:887-94. 2015
    ....
  24. doi Genetics of primary macronodular adrenal hyperplasia
    Maria Candida Barisson Villares Fragoso
    Unidade de SuprarrenalDisciplina de Endocrinologia e Metabologia, Hospital das Clinicas, Faculdade de Medicina da Universidade de Sao Paulo, Sao Paulo, BrazilInstituto do Câncer de São Paulo ICESPSão Paulo, BrazilDépartement de MédecineCentre Hospitalier de l Université de Montréal, Montreal, Quebec, Canada Unidade de SuprarrenalDisciplina de Endocrinologia e Metabologia, Hospital das Clinicas, Faculdade de Medicina da Universidade de Sao Paulo, Sao Paulo, BrazilInstituto do Câncer de São Paulo ICESPSão Paulo, BrazilDépartement de MédecineCentre Hospitalier de l Université de Montréal, Montreal, Quebec, Canada
    J Endocrinol 224:R31-43. 2015
    ..The purpose of this review is therefore to present new insights on the molecular and genetic profile of PMAH pathophysiology, and to discuss the implications for disease progression. ..
  25. doi Adrenal incidentalomas and subclinical Cushing's syndrome: diagnosis and treatment
    Tânia Longo Mazzuco
    Division of Endocrinology, Department of Medicine, Centre Hospitalier de l Universite de Montreal CHUM, Universite de Montreal, Quebec, Canada
    Curr Opin Endocrinol Diabetes Obes 16:203-10. 2009
    ..The recognition of endocrine and metabolic dysfunctions associated with subclinical hypercortisolism leads to current awareness about its potential consequences...
  26. doi ARMC5 mutations are a frequent cause of primary macronodular adrenal Hyperplasia
    Guilherme Asmar Alencar
    Unidade de Suprarrenal G A A, A M L, M Y N, B M d P M, M Q A, M A A P, B B M, M C B V F, Disciplina de Endocrinologia e Metabologia, Laboratório de Hormônios e Genética Molecular LIM42, Hospital das Clinicas, Faculdade de Medicina da Universidade de Sao Paulo, São Paulo 05403900, Brazil Département de Médecine J T, P H, I B, A L, Centre Hospitalier de l Universite de Montreal, Montreal H2W 1T8, Canada Departamento de Patologia M C N Z, Faculdade de Medicina da Universidade de Sao Paulo, São Paulo 05403900, Brazil Departamento de Radiologia G C G, M d S R, Hospital das Clinicas, Faculdade de Medicina da Universidade de Sao Paulo, São Paulo 05403900, Brazil and Disciplina de Urologia, Departamento de Cirurgia J L C, Faculdade de Medicina da Universidade de Sao Paulo, São Paulo 05403900, Brazil
    J Clin Endocrinol Metab 99:E1501-9. 2014
    ..Familial clustering of PMAH has been described, suggesting an inherited genetic cause for this condition...
  27. ncbi Loss of brain volume in endogenous Cushing's syndrome and its reversibility after correction of hypercortisolism
    Isabelle Bourdeau
    Department of Medicine and Department of Diagnostic Radiology, Division of Endocrinology, Centre Hospitalier de l Universite de Montreal, Montreal, Canada H2W 1T8
    J Clin Endocrinol Metab 87:1949-54. 2002
    ..001), bicaudate diameter (P < 0.0005), and subjective evaluation (P = 0.05). We conclude that brain volume loss is highly prevalent in CS and is at least partially reversible following correction of hypercortisolism...
  28. ncbi Aberrant membrane hormone receptors in incidentally discovered bilateral macronodular adrenal hyperplasia with subclinical Cushing's syndrome
    I Bourdeau
    Division of Endocrinology, Department of Medicine, Research Center, , , Canada H2W 1T8
    J Clin Endocrinol Metab 86:5534-40. 2001
    ..This study demonstrates that subclinical secretion of cortisol can be regulated via the aberrant function of at least V1-vasopressin, LH/hCG, or 5-HT4 receptors in incidentally identified bilateral macronodular adrenal hyperplasia...
  29. ncbi The theory of use behind telemedicine: how compatible with physicians' clinical routines?
    P Lehoux
    Interdisciplinary Health Research Group GRIS, Department of Health Administration, University of Montreal, Branch Centre Ville, Quebec, Canada
    Soc Sci Med 54:889-904. 2002
    ....
  30. ncbi International concerted action on collaboration in telemedicine: G8 sub-project 4
    A Lacroix
    Telemedicine Unit, Centre Hospitalier de l Universite de Montreal CHUM, Quebec, Canada
    Stud Health Technol Inform 64:12-9. 1999
    ..More detailed information on this project and summaries of the initial FORUMS are found on our Web site at www.g7sp4.org...
  31. ncbi Theory of use behind telehealth applications
    P Lehoux
    Dept of Health Administration, University of Montreal, Quebec, Canada
    Stud Health Technol Inform 64:29-38. 1999
    ....
  32. pmc First case report of an adrenocortical carcinoma caused by a BRCA2 mutation
    Nada El Ghorayeb
    aDivision of Endocrinology bDepartment of Pathology cDivision of Clinical Genetics, Department of Medicine and Research Center CRCHUM, Centre Hospitalier de l Universite de Montreal, Montreal, QC, Canada
    Medicine (Baltimore) 95:e4756. 2016
    ..Adrenocortical carcinoma (ACC) may rarely be a component of inherited cancer syndromes such as Li-Fraumeni syndrome and Beckwith-Wiedemann syndrome. ACC caused by a BRCA2 mutation has never been reported...
  33. doi Pheochromocytomas are diagnosed incidentally and at older age in neurofibromatosis type 1
    Jessica Moramarco
    Division of Endocrinology, Department of Medicine, Centre de recherche du Centre Hospitalier de l Universite de Montreal, Montreal, Quebec, Canada
    Clin Endocrinol (Oxf) . 2016
    ....
  34. doi Pasireotide monotherapy in Cushing's disease: a single-centre experience with 5-year extension of phase III Trial
    Jessica MacKenzie Feder
    Division of Endocrinology, Department of Medicine and Research Center, Centre hospitalier de l Université de Montréal CHUM Hôtel Dieu, 3850 Saint Urbain Street, Montreal, QC, H2W 1T8, Canada
    Pituitary 17:519-29. 2014
    ..We report the experience with 4 patients in our center of which 2 full responders have completed 5.5 and 4.25 years of treatment with disease control...
  35. ncbi Classic and recent etiologies of Cushing's syndrome: diagnosis and therapy
    Catherine Beauregard
    Department of Medicine, Research Center, Hôtel Dieu du Centre hospitalier de 1 Université de Montreal CHUM, Montreal, Quebec, Canada
    Treat Endocrinol 1:79-94. 2002
    ..The long-term follow-up of patients treated for Cushing's syndrome should include the adequate replacement of glucocorticoids and other hormones, treatment of osteoporosis, and detection of long-term relapse of Cushing's syndrome...
  36. doi Recent advances in adrenocortical carcinoma in adults
    Isabelle Bourdeau
    Division of Endocrinology, Department of Medicine and Research Center, Centre Hospitalier de l Universite de Montreal CHUM, Montreal, Quebec, Canada
    Curr Opin Endocrinol Diabetes Obes 20:192-7. 2013
    ..So far, studies with large cohorts of patients affected by ACC were lacking because of the rarity of the disease; however, recent international and multicenter collaborative studies provide new insights in the management of ACC...
  37. ncbi Adrenocortical overexpression of gastric inhibitory polypeptide receptor underlies food-dependent Cushing's syndrome
    N N'Diaye
    Department of Medicine, Research Center, Campus Hotel Dieu, Centre Hospitalier de l Universite de Montreal, Quebec, Canada
    J Clin Endocrinol Metab 83:2781-5. 1998
    ..We conclude that the GIPR overexpression and its coupling to steroidogenesis underlie GIP-dependent Cushing's syndrome...
  38. ncbi Hormone receptor abnormalities in adrenal Cushing's syndrome
    J Tremblay
    Department of Medicine, Research Center, , , Canada
    Horm Metab Res 30:440-6. 1998
    ....
  39. pmc Role of ACTH and Other Hormones in the Regulation of Aldosterone Production in Primary Aldosteronism
    Nada El Ghorayeb
    Department of Medicine, Division of Endocrinology, Centre de recherche du Centre hospitalier de l Université de Montréal CRCHUM, Universite de Montreal, Montreal, QC, Canada
    Front Endocrinol (Lausanne) 7:72. 2016
    ..This review will focus on the role of ACTH on excess aldosterone secretion in PA with particular focus on the aberrant expression of MC2R in comparison with other aberrant ligands and their GPCRs in this frequent pathology. ..
  40. ncbi Training the next generation of researchers in work disability prevention: the Canadian Work Disability Prevention CIHR Strategic Training Program
    Patrick Loisel
    Universite de Sherbrooke, Sherbrooke, Quebec, Canada
    J Occup Rehabil 15:273-84. 2005
    ..Training programs attracting high-quality applicants and taking into account the complexity of this emerging field are urgently needed...
  41. doi Cabergoline monotherapy in the long-term treatment of Cushing's disease
    Ariane Godbout
    Endocrinology Division, Department of Medicine, Centre de recherche du Centre hospitalier de l Université de Montréal CRCHUM, Hotel Dieu du CHUM, 3840 rue Saint Urbain, Montreal, Quebec, Canada
    Eur J Endocrinol 163:709-16. 2010
    ..Identification of D(2) receptors in corticotroph tumors led to clinical trials of cabergoline therapy in limited cases of Nelson's syndrome, ectopic ACTH-secreting tumors, and recently Cushing's disease (CD)...
  42. pmc Role of Brg1 and HDAC2 in GR trans-repression of the pituitary POMC gene and misexpression in Cushing disease
    Steve Bilodeau
    Laboratoire de Genetique Moleculaire, Institut de recherches cliniques de Montreal IRCM, Montreal, Quebec H2W 1R7, Canada
    Genes Dev 20:2871-86. 2006
    ..In addition to providing a molecular basis for Gc resistance, these deficiencies may also contribute to the tumorigenic process...
  43. doi Bilateral adrenalectomy in the 21st century: when to use it for hypercortisolism?
    Carole Guerin
    Aix Marseille UniversityAssistance Publique Hopitaux de Marseille, Department of Endocrine Surgery, La Conception Hospital, Marseille, FranceAix Marseille UniversityAssistance Publique Hopitaux de Marseille, Department of Nuclear Medicine, La Timone Hospital, Marseille, FranceDepartment of Nuclear MedicineThyroid and PET CT Center, Oncology Institute of Southern Switzerland, Bellinzona and Lugano, SwitzerlandAix Marseille UniversityAssistance Publique Hopitaux de Marseille, Department of Endocrinology, La Conception Hospital, 147 Boulevard Baille, 13005 Marseille, FranceEndocrine DivisionDepartment of Medicine, Centre Hospitalier de l Universite de Montreal CHUM, Montreal, Canada
    Endocr Relat Cancer 23:R131-42. 2016
    ..The objective of this review is to compare the efficacy and side effects of the various therapeutic options of hypercortisolism with those of bilateral adrenalectomy, in order to better define its indications in the 21st century. ..
  44. doi Multiple aberrant hormone receptors in Cushing's syndrome
    Nada El Ghorayeb
    Division of EndocrinologyDepartment of Medicine, Centre de Recherche du CHUM CRCHUM, Universite de Montreal, 900, rue Saint Denis, Room R08 474, Montreal, Quebec H2X 0A9, Canada
    Eur J Endocrinol 173:M45-60. 2015
    ..Targeted therapies to block the aberrant receptors or their ligands could become useful in the future. ..
  45. doi Coaxial guide wire placement in the right adrenal vein for repeated adrenal venous samplings
    Youri Kaitoukov
    Division of Interventional Radiology, Department of Radiology, Centre Hospitalier de l Universite de Montreal CHUM, 3840 Saint Urbain St, Montreal, QC, H2W 1T8, Canada
    Cardiovasc Intervent Radiol 37:795-9. 2014
    ..The aim of our study was to evaluate guide wire insertion into the right adrenal vein catheter to sustain AVS selectivity (adrenal/peripheral cortisol ratio [Ca/Cp]) over time...
  46. doi Primary bilateral macronodular adrenal hyperplasia
    Agostino De Venanzi
    aDivision of Endocrinology, Department of Medicine, Centre de recherche du Centre hospitalier de l Université de Montréal CRCHUM, Universite de Montreal, Montreal, Quebec H2W 1T8, Canada bUnidade de Suprarrenal, Disciplina de Endocrinologia e Metabologia, Laboratório de Hormônios e Genética Molecular LIM42, Hospital das Clinicas, Faculdade de Medicina da Universidade de Sao Paulo, Sao Paulo, Brazil
    Curr Opin Endocrinol Diabetes Obes 21:177-84. 2014
    ..We summarize the recent insights concerning its epidemiology, diagnosis, genetics, pathophysiology, and therapeutic options...
  47. ncbi Cognitive function and cerebral assessment in patients who have Cushing's syndrome
    Isabelle Bourdeau
    Division of Endocrinology, Department of Medicine, Hôtel Dieu du Centre hospitalier de l Université de Montréal, 3840 Saint Urbain street, Montreal, Quebec H2W 1T8, Canada
    Endocrinol Metab Clin North Am 34:357-69, ix. 2005
    ..In addition, there is a high incidence of apparent diffuse loss of brain volume in patients who have CS. Recent studies indicate at least partial reversibility of these abnormalities following correction of hypercortisolism...
  48. ncbi Analysis of the putative regulatory region of the gastric inhibitory polypeptide receptor gene in food-dependent Cushing's syndrome
    S R Antonini
    Laboratories of Endocrine Pathophysiology, Cellular Biology of Hypertension, and Molecular Medicine, Department of Medicine, Hôtel Dieu du Centre hospitalier de l Université de Montréal CHUM, Montreal, Canada H2W 1T8
    J Steroid Biochem Mol Biol 91:171-7. 2004
    ..In conclusion, mutations or SNPs in the regulatory region of the GIPR gene are unlikely to underlie GIP-dependent CS...
  49. doi Aberrant hormone receptors in primary aldosteronism
    T L Mazzuco
    Division of Endocrinology, Department of Medicine, Centre de recherche du Centre hospitalier de l Université de Montréal CRCHUM, Universite de Montreal, Montreal, Canada
    Horm Metab Res 42:416-23. 2010
    ..The identification of aberrant adrenal GPCRs by in vivo functional studies offers the potential for novel pharmacological therapies that either suppress the endogenous ligands or block the receptor with specific antagonists...
  50. doi Clinical and biochemical features of seven adult adrenal ganglioneuromas
    G Rondeau
    Division of Endocrinology, Department of Medicine, Centre Hospitalier de l Universite de Montreal Hotel Dieu, 3850, Saint Urbain Street, Montreal, Quebec, Canada H2W 1T7
    J Clin Endocrinol Metab 95:3118-25. 2010
    ..Adrenal ganglioneuroma (GN) is seldom considered in the differential diagnosis of adrenal lesions, and its clinical presentation is not well known...
  51. ncbi Long-term brain metabolic alterations in exogenous Cushing's syndrome as monitored by proton magnetic resonance spectroscopy
    A Khiat
    , , 1058 St-Denis, , , Canada H2X 3J4
    Brain Res 911:134-40. 2001
    ..The Cho/H(2)O reductions were not found to be dose- or age-dependent. Other metabolite ratios did not vary with treatment period, dose or age...
  52. ncbi Partial characterisation of the 5' flanking region of the human GIP receptor (GIPR) gene
    V Baldacchino
    Laboratory of Endocrine Pathophysiology, Dept of Medicine, Hôtel Dieu du Centre hospitalier de l Université de Montréal CHUM, Montreal, Canada, H2W 1T8
    Endocr Res 28:577. 2002
  53. ncbi The Sp transcription factor family is involved in the cellular expression of the human GIP-R gene promoter
    V Baldacchino
    Laboratory of Endocrine Pathophysiology, Department of Medicine, Hôtel Dieu du Centre hospitalier de l Université de Montréal, Montreal, Canada
    Endocr Res 30:805-6. 2004
  54. ncbi The reliability of recollections of family history: implications for the medical provider
    M E Parent
    Department of Nutrition, Faculty of Medicine, Universite de Montreal, Quebec, Canada
    J Cancer Educ 12:114-20. 1997
    ..Moreover, the methods used in previous studies to elicit the family reports render their applicability to the medical setting questionable...