Nicolaas Paul L G Verhoeff
Affiliation: Kunin-Lunenfeld Applied Research Unit
- Pharmacotherapy of agitation and psychotic symptoms in Alzheimer's diseaseNicolaas P L G Verhoeff
Kunin Lunenfeld Applied Research Unit, Posluns Building, 7th Floor, Room 762, Baycrest Centre for Geriatric Care, 3560 Bathurst Street, Toronto, ON M6A 2E1, Canada
Expert Rev Neurother 2:655-64. 2002..A future perspective is provided, taking into consideration prospective developments in preventative treatments of Alzheimer's disease over the next 5 years...
- Amyloid imaging in vivo: implications for Alzheimer's disease managementNicolaas Plg Verhoeff
Diplomate of the American Board of Psychiatry and Neurology, Inc, Member Board of the American Board of Medical Specialities, Associate Professor of Psychiatry, Clinical Research Scientist, University of Toronto, Kunin Lunenfeld Applied Research Unit, Baycrest Brain Health Complex, 7th Floor, Room 762, 3560 Bathurst Street, Toronto, Ontario M6A 2E1, Canada 1 416 785 2500 2167 1 416 785 4230
Expert Opin Med Diagn 1:337-49. 2007....
- Effects of catecholamine depletion on D2 receptor binding, mood, and attentiveness in humans: a replication studyNicolaas P L G Verhoeff
Kunin Lunenfeld Applied Research Unit, Baycrest Centre for Geriatric Care, Posluns Building, 7th Floor, Room 762, 3560 Bathurst Street, Toronto, Ontario, Canada M6A 2E1
Pharmacol Biochem Behav 74:425-32. 2003..These changes were not correlated with the D(2)RBP increments. The results of this study are overall consistent with previous findings by our group using the same methodology in a different cohort of six healthy subjects...
- In-vivo imaging of Alzheimer disease beta-amyloid with [11C]SB-13 PETNicolaas P L G Verhoeff
Vivian Rakoff PET Centre, Centre for Addiction and Mental Health, Ontario, Canada
Am J Geriatr Psychiatry 12:584-95. 2004..The authors' aim was to develop a novel Abeta-specific positron-emission tomography (PET) tracer...
- Acetylcholinergic neurotransmission and the beta-amyloid cascade: implications for Alzheimer's diseaseNicolaas Paul L G Verhoeff
Department of Psychiatry, Faculty of Medicine, University of Toronto, Canada
Expert Rev Neurother 5:277-84. 2005..Various suggestions are made on how such potential disease-modifying effects could be studied in the future...
- Quantitative imaging of neuroinflammation in human white matter: a positron emission tomography study with translocator protein 18 kDa radioligand, [18F]-FEPPAIvonne Suridjan
Research Imaging Centre, Centre for Addiction and Mental Health, Toronto, Ontario, M5T 1R8, Canada Institute of Medical Science, University of Toronto, Ontario, M5S 1A8, Canada
Synapse 68:536-47. 2014..The VT values were 15% higher in HAB than in MAB, although the difference was not statistically significant. This study provides evidence for the utility and limitations of [18F]-FEPPA PET to measure TSPO expression in WM...
- Effect of subthalamic stimulation on mood state in Parkinson's disease: evaluation of previous facts and problemsShinichiro Takeshita
Kunin Lunenfeld Applied Research Unit, Baycrest Centre for Geriatric Care, University of Toronto, Toronto, Ontario, Canada
Neurosurg Rev 28:179-86; discussion 187. 2005..It may be crucial to reduce the variation in the results by, for example, the use of standardized protocols and the precise verification of the stimulated region in further investigations to address this issue...
- Cortical gamma-aminobutyric acid type A-benzodiazepine receptors in recovery from alcohol dependence: relationship to features of alcohol dependence and cigarette smokingJulie K Staley
Yale University School of Medicine, 950 Campbell Avenue, New Haven, CT 06516, USA
Arch Gen Psychiatry 62:877-88. 2005..Adaptations in gamma-aminobutyric acid type A (GABA(A))-benzodiazepine receptors contribute to the neurobiology of human alcohol dependence and withdrawal...