P I Karakiewicz

Summary

Country: Canada

Publications

  1. pmc Development and validation of a nomogram predicting the outcome of prostate biopsy based on patient age, digital rectal examination and serum prostate specific antigen
    Pierre I Karakiewicz
    Department of Urology, University of Montreal, Montreal, Quebec, Canada
    J Urol 173:1930-4. 2005
  2. ncbi Prognostic impact of positive surgical margins in surgically treated prostate cancer: multi-institutional assessment of 5831 patients
    Pierre I Karakiewicz
    Department of Urology, Memorial Sloan Kettering Cancer Center, New York, New York, USA
    Urology 66:1245-50. 2005
  3. ncbi Tumor size improves the accuracy of TNM predictions in patients with renal cancer
    Pierre I Karakiewicz
    Cancer Prognostics and Health Outcomes Unit, University of Montreal, Montreal, Que, Canada
    Eur Urol 50:521-8; discussion 529. 2006
  4. ncbi Outcomes research: a methodologic review
    Pierre I Karakiewicz
    Cancer Prognostics and Health Outcomes Unit, University of Montreal, Canada
    Eur Urol 50:218-24. 2006
  5. ncbi Precystectomy nomogram for prediction of advanced bladder cancer stage
    Pierre I Karakiewicz
    Cancer Prognostics and Health Outcomes Unit, University of Montreal, Montreal, Quebec, Canada
    Eur Urol 50:1254-60; discussion 1261-2. 2006
  6. ncbi Renal cell carcinoma with nodal metastases in the absence of distant metastatic disease: prognostic indicators of disease-specific survival
    Pierre I Karakiewicz
    Cancer Prognostics and Health Outcome Unit, University of Montreal Health Center, Montreal, Quebec, Canada, and Department of Urology, Rennes University Hospital, France
    Eur Urol 51:1616-24. 2007
  7. ncbi Chronic inflammation is negatively associated with prostate cancer and high-grade prostatic intraepithelial neoplasia on needle biopsy
    P I Karakiewicz
    Department of Urology, Cancer Prognostics and Health Outcomes Unit, University of Montreal, 1058 rue St Denis, Montreal, Quebec, Canada
    Int J Clin Pract 61:425-30. 2007
  8. ncbi Collecting duct renal cell carcinoma: a matched analysis of 41 cases
    Pierre I Karakiewicz
    Cancer Prognostics and Health Outcome Unit, University of Montreal Health Centre, Montreal, QC, Canada
    Eur Urol 52:1140-5. 2007
  9. ncbi ECOG performance status 0 or 1 and symptom classification do not improve the ability to predict renal cell carcinoma-specific survival
    Pierre I Karakiewicz
    Cancer Prognostics and Health Outcomes Unit, University of Montreal Health Center CHUM, 1058, rue St Denis, Montreal, Que, Canada H2X 3J4
    Eur J Cancer 43:1023-9. 2007
  10. ncbi Multi-institutional validation of a new renal cancer-specific survival nomogram
    Pierre I Karakiewicz
    Cancer Prognostics and Health Outcomes Unit, University of Montreal Health Center, Montreal, Quebec, Canada
    J Clin Oncol 25:1316-22. 2007

Collaborators

Detail Information

Publications117 found, 100 shown here

  1. pmc Development and validation of a nomogram predicting the outcome of prostate biopsy based on patient age, digital rectal examination and serum prostate specific antigen
    Pierre I Karakiewicz
    Department of Urology, University of Montreal, Montreal, Quebec, Canada
    J Urol 173:1930-4. 2005
    ..We developed and validated a nomogram which predicts presence of prostate cancer (PCa) on needle biopsy...
  2. ncbi Prognostic impact of positive surgical margins in surgically treated prostate cancer: multi-institutional assessment of 5831 patients
    Pierre I Karakiewicz
    Department of Urology, Memorial Sloan Kettering Cancer Center, New York, New York, USA
    Urology 66:1245-50. 2005
    ....
  3. ncbi Tumor size improves the accuracy of TNM predictions in patients with renal cancer
    Pierre I Karakiewicz
    Cancer Prognostics and Health Outcomes Unit, University of Montreal, Montreal, Que, Canada
    Eur Urol 50:521-8; discussion 529. 2006
    ..We examined the increment in accuracy related to inclusion of pathologically determined tumor size in prediction of nodal metastases (N+), distant metastases (M+), and cancer-specific survival (CSS)...
  4. ncbi Outcomes research: a methodologic review
    Pierre I Karakiewicz
    Cancer Prognostics and Health Outcomes Unit, University of Montreal, Canada
    Eur Urol 50:218-24. 2006
    ..We explored the history and conceptual trends of outcomes research...
  5. ncbi Precystectomy nomogram for prediction of advanced bladder cancer stage
    Pierre I Karakiewicz
    Cancer Prognostics and Health Outcomes Unit, University of Montreal, Montreal, Quebec, Canada
    Eur Urol 50:1254-60; discussion 1261-2. 2006
    ..To evaluate precystectomy prediction of pT and pN stages at cystectomy...
  6. ncbi Renal cell carcinoma with nodal metastases in the absence of distant metastatic disease: prognostic indicators of disease-specific survival
    Pierre I Karakiewicz
    Cancer Prognostics and Health Outcome Unit, University of Montreal Health Center, Montreal, Quebec, Canada, and Department of Urology, Rennes University Hospital, France
    Eur Urol 51:1616-24. 2007
    ..We explored the ability of standard risk factors such as tumour size, Fuhrman grade, histologic subtype and symptom classification to predict renal cell carcinoma-specific survival (RCC-SS)...
  7. ncbi Chronic inflammation is negatively associated with prostate cancer and high-grade prostatic intraepithelial neoplasia on needle biopsy
    P I Karakiewicz
    Department of Urology, Cancer Prognostics and Health Outcomes Unit, University of Montreal, 1058 rue St Denis, Montreal, Quebec, Canada
    Int J Clin Pract 61:425-30. 2007
    ..Chronic inflammation is more frequent in the presence of benign histology than it is in the presence of PCa or HGPIN...
  8. ncbi Collecting duct renal cell carcinoma: a matched analysis of 41 cases
    Pierre I Karakiewicz
    Cancer Prognostics and Health Outcome Unit, University of Montreal Health Centre, Montreal, QC, Canada
    Eur Urol 52:1140-5. 2007
    ..We assessed the stage and histologic features of patients with CDRCC and compared cancer-specific mortality in CDRCC and matched patients with clear-cell renal cell carcinoma (CRCC)...
  9. ncbi ECOG performance status 0 or 1 and symptom classification do not improve the ability to predict renal cell carcinoma-specific survival
    Pierre I Karakiewicz
    Cancer Prognostics and Health Outcomes Unit, University of Montreal Health Center CHUM, 1058, rue St Denis, Montreal, Que, Canada H2X 3J4
    Eur J Cancer 43:1023-9. 2007
    ..We tested and compared the improvement in prognostic ability related to the consideration of either ECOG performance status (ECOGPS) and/or symptom classification (S-CLASS) in renal cell carcinoma specific mortality (RCC-SM) predictions...
  10. ncbi Multi-institutional validation of a new renal cancer-specific survival nomogram
    Pierre I Karakiewicz
    Cancer Prognostics and Health Outcomes Unit, University of Montreal Health Center, Montreal, Quebec, Canada
    J Clin Oncol 25:1316-22. 2007
    ..We tested the hypothesis that the prediction of renal cancer-specific survival can be improved if traditional predictor variables are used within a prognostic nomogram...
  11. ncbi Platelet count and preoperative haemoglobin do not significantly increase the performance of established predictors of renal cell carcinoma-specific mortality
    Pierre I Karakiewicz
    Cancer Prognostics and Health Outcome Unit, University of Montreal Health Center, Montreal, Quebec, Canada
    Eur Urol 52:1428-36. 2007
    ..Anaemia and/or thrombocytosis were identified as independent predictors of poor survival in renal cell carcinoma (RCC). We tested the extent to which these markers worsen the prognosis in these patients...
  12. ncbi C-reactive protein is an informative predictor of renal cell carcinoma-specific mortality: a European study of 313 patients
    Pierre I Karakiewicz
    Cancer Prognostics and Health Outcomes Unit, University of Montreal Health Center, Montreal, Quebec, Canada
    Cancer 110:1241-7. 2007
    ..It was hypothesized that CRP can improve the prognostic ability of standard RCC-specific mortality (RCC-SM) predictors in patients treated with nephrectomy for all stages of RCC...
  13. ncbi Predicting cancer-control outcomes in patients with renal cell carcinoma
    Pierre I Karakiewicz
    Cancer Prognostics and Health Outcomes Unit, University of Montreal Health Center, Montreal, Quebec, Canada
    Curr Opin Urol 17:295-302. 2007
    ..Various prognostic models and nomograms can assist with treatment decision-making in patients with renal cell carcinoma...
  14. ncbi Neoadjuvant sutent induction therapy may effectively down-stage renal cell carcinoma atrial thrombi
    Pierre I Karakiewicz
    Cancer Prognostics and Health Outcomes Unit, University of Montreal, Montreal, QC, Canada
    Eur Urol 53:845-8. 2008
    ..The patient refused the sternotomy. She was offered two cycles of sunitinib maleate (Sutent) induction therapy to down-stage the thrombus and to reduce the extent of the surgery...
  15. doi Predictive models and prostate cancer
    Pierre I Karakiewicz
    University of Montreal Health Center CHUM, 1058 rue St Denis, Montreal, QC H2X 3J4, Canada
    Nat Clin Pract Urol 5:82-92. 2008
    ..The preoperative nomogram for prediction of biochemical recurrence, introduced by Kattan and colleagues, has been updated and predicts up to 10 years after radical prostatectomy...
  16. doi Biopsies performed at tertiary care centers are superior to referral biopsies in predicting pathologic Gleason sum
    Pierre I Karakiewicz
    Cancer Prognostics and Health Outcomes Unit, University of Montreal, Montreal, Quebec, Canada
    J Endourol 22:533-8. 2008
    ..Biopsy grading at tertiary care centers may or may not be superior to biopsies performed at referral institutions...
  17. doi The effect of comorbidity and socioeconomic status on sexual and urinary function and on general health-related quality of life in men treated with radical prostatectomy for localized prostate cancer
    Pierre I Karakiewicz
    University of Montreal Health Center CHUM Cancer Prognostics and Health Outcomes Unit, Montreal, Canada
    J Sex Med 5:919-27. 2008
    ..Therefore, valid interpretation of cancer control outcomes requires adjustment for HRQOL...
  18. doi External validation of the updated Partin tables in a cohort of North American men
    Pierre I Karakiewicz
    Cancer Prognostics and Health Outcomes Unit and Department of Urology, University of Montreal, Montreal, Quebec, Canada
    J Urol 180:898-902; discussion 902-3. 2008
    ..The Partin tables were updated in 2007. However, to our knowledge their accuracy and performance characteristics have not been confirmed in an external validation cohort...
  19. doi Predicting outcomes in patients with urologic cancers
    Pierre I Karakiewicz
    Cancer Prognostics and Health Outcomes Unit, University of Montreal Health Center, Montreal, Quebec, Canada
    Curr Opin Support Palliat Care 1:153-68. 2007
    ..To review the available predictive and prognostic models addressing oncological outcomes in patients with bladder, kidney and prostate cancer...
  20. doi A preoperative prognostic model for patients treated with nephrectomy for renal cell carcinoma
    Pierre I Karakiewicz
    Cancer Prognostics and Health Outcomes Unit, University of Montreal Health Center, Montreal, QC, Canada
    Eur Urol 55:287-95. 2009
    ..Currently two pretreatment prognostic models with limited accuracy (65-67%) can be used to predict survival in patients with localized renal cell carcinoma (RCC)...
  21. doi Conditional survival predictions after nephrectomy for renal cell carcinoma
    Pierre I Karakiewicz
    Cancer Prognostics and Health Outcomes Unit, University of Montreal, Montreal, Quebec, Canada
    J Urol 182:2607-12. 2009
    ..Conditional survival implies that on average long-term cancer survivors have a better prognosis than do newly diagnosed individuals. We explored the effect of conditional survival in renal cell carcinoma...
  22. doi Predicting the risk of lymph node invasion during radical prostatectomy using the European Association of Urology guideline nomogram: a validation study
    J Schmitges
    Martini Clinic, Prostate Cancer Center, Hamburg, Germany
    Eur J Surg Oncol 38:624-9. 2012
    ....
  23. ncbi Lymphovascular invasion is independently associated with overall survival, cause-specific survival, and local and distant recurrence in patients with negative lymph nodes at radical cystectomy
    Yair Lotan
    Department of Urology, The University of Texas Southwestern Medical Center at Dallas, Dallas, TX 75390 9110, USA
    J Clin Oncol 23:6533-9. 2005
    ..We hypothesized that bladder cancer patients with associated lymphovascular invasion (LVI) are at increased risk of occult metastases...
  24. doi A population based assessment of perioperative mortality after cystectomy for bladder cancer
    Hendrik Isbarn
    Cancer Prognostics and Health Outcomes Unit, University of Montreal Health Center, Montreal, Quebec, Canada
    J Urol 182:70-7. 2009
    ..Contemporary estimates range from 0.7% to 5.6%. We tested several predictors of perioperative mortality and devised a model for individual perioperative mortality prediction...
  25. doi Limited prognostic value of tumor necrosis in patients with renal cell carcinoma
    Hendrik Isbarn
    Cancer Prognostics and Health Outcomes Unit, University of Montreal Health Center, Montreal, Quebec, Canada
    Urology 75:1378-84. 2010
    ..However, its added prognostic value along with established cancer-specific mortality (CSM) predictors has never been formally tested...
  26. doi Diabetes mellitus without metformin intake is associated with worse oncologic outcomes after radical nephroureterectomy for upper tract urothelial carcinoma
    M Rieken
    Department of Urology, Weill Cornell Medical College, New York Presbyterian Hospital, New York, NY, USA Department of Urology, University Hospital Basel, Basel, Switzerland
    Eur J Surg Oncol 40:113-20. 2014
    ..We tested the hypothesis that DM and metformin use impact oncologic outcomes of patients treated with radical nephroureterectomy (RNU) for UTUC...
  27. doi Nomogram predicting the probability of early recurrence after radical prostatectomy for prostate cancer
    Jochen Walz
    Cancer Prognostics and Health Outcomes Unit, University of Montreal, Montreal, Canada
    J Urol 181:601-7; discussion 607-8. 2009
    ..Identifying patients at risk for early recurrence may improve prognosis as early institution of adjuvant therapy may reduce the risk of progression...
  28. doi Predictive value of combined immunohistochemical markers in patients with pT1 urothelial carcinoma at radical cystectomy
    Shahrokh F Shariat
    Department of Urology, University of Texas Southwestern Medical Center, Dallas, Texas, USA
    J Urol 182:78-84; discussion 84. 2009
    ..We tested whether the combination of immunohistochemical markers could risk stratify cases of pT1 urothelial carcinoma of the bladder at radical cystectomy...
  29. ncbi Plasminogen activation inhibitor-1 improves the predictive accuracy of prostate cancer nomograms
    Shahrokh F Shariat
    Department of Urology, University of Texas Southwestern Medical Center, Dallas, Texas 75390 9110, USA
    J Urol 178:1229-36; discussion 1236-7. 2007
    ....
  30. doi Risk-adjusted hazard rates of biochemical recurrence for prostate cancer patients after radical prostatectomy
    Jochen Walz
    Cancer Prognostics and Health Outcomes Unit, University of Montreal, Montreal, Quebec, Canada
    Eur Urol 55:412-19. 2009
    ..Current prostate cancer (PCa) follow-up guidelines do not account for the risk of disease relapse...
  31. ncbi The 2002 AJCC pT2 substages confer no prognostic information on the rate of biochemical recurrence after radical prostatectomy
    Felix K H Chun
    Cancer Prognostics and Health Outcomes Unit and the Department of Urology, University of Montreal Health Center, Montreal, Canada
    Eur Urol 49:273-8; discussion 278-9. 2006
    ..We examined the prognostic value of AJCC pT2 substages in prediction of biochemical recurrence (BCR) after radical prostatectomy (RP), in European patients...
  32. ncbi Pre-treatment nomogram for disease-specific survival of patients with chemotherapy-naive androgen independent prostate cancer
    Robert Svatek
    Department of Urology, The University of Texas Southwestern Medical Center at Dallas, 5323 Harry Hines Blvd J8 112, Dallas, Texas 75390 9110, USA
    Eur Urol 49:666-74. 2006
    ..Our objective was to develop a nomogram that predicts the probability of cancer-specific survival in men with untreated androgen-independent prostate cancer (AIPC)...
  33. ncbi Patients with renal cell carcinoma nodal metastases can be accurately identified: external validation of a new nomogram
    Georg C Hutterer
    Cancer Prognostics and Health Outcomes Unit, University of Montreal Health Center, Montreal, QC, Canada
    Int J Cancer 121:2556-61. 2007
    ..More thorough staging can hopefully better select those in whom adjuvant treatment is necessary. (c) 2007 Wiley-Liss, Inc...
  34. doi Inventory of prostate cancer predictive tools
    Shahrokh F Shariat
    Department of Urology, University of Texas Southwestern Medical Centre, Dallas, Texas 75390 9110, USA
    Curr Opin Urol 18:279-96. 2008
    ..We describe the patient populations to which they apply and the outcomes predicted, and record their individual characteristics...
  35. doi Biopsy core number represents one of foremost predictors of clinically significant gleason sum upgrading in patients with low-risk prostate cancer
    Umberto Capitanio
    Cancer Prognostics and Health Outcomes Unit, University of Montreal Health Center, Montreal, Quebec, Canada
    Urology 73:1087-91. 2009
    ..To examine the effect the number of biopsy cores taken has on the rate of clinically significant Gleason sum upgrading (GSU) in patients with low-risk prostate cancer...
  36. doi Differential effect on survival of pelvic lymph node dissection at radical cystectomy for muscle invasive bladder cancer
    A Larcher
    Cancer Prognostics and Health Outcomes Unit, University of Montreal Health Center, Montreal, Canada Division of Oncology, Unit of Urology, URI, IRCCS Ospedale San Raffaele, Milan, Italy Electronic address
    Eur J Surg Oncol 41:353-60. 2015
    ..To compare long-term cancer outcomes after radical cystectomy (RC) alone or RC with pelvic lymph node dissection (PLND) according to different age and comorbidities categories...
  37. doi The effect of age at diagnosis on prostate cancer mortality: a grade-for-grade and stage-for-stage analysis
    G Gandaglia
    Cancer Prognostics and Health Outcomes Unit, University of Montreal Health Centre, Montreal, Canada Division of Oncology Unit of Urology, URI, IRCCS Ospedale San Raffaele, Milan, Italy Electronic address
    Eur J Surg Oncol 40:1706-15. 2014
    ..To evaluate the effect of advancing age on cancer-specific mortality (CSM) after radical prostatectomy (RP)...
  38. doi Contemporary 90-day mortality rates after radical cystectomy in the elderly
    J Schiffmann
    Cancer Prognostics and Health Outcomes Unit, University of Montreal Health Center, Montreal, Canada Martini Clinic Prostate Cancer Center, University Medical Center Hamburg Eppendorf, Hamburg, Germany Electronic address
    Eur J Surg Oncol 40:1738-45. 2014
    ..Existing radical cystectomy (RC) perioperative mortality estimates may underestimate the contemporary rates due to more advanced age, more baseline comorbidities and potentially broader inclusion criteria for RC, relative to past criteria...
  39. doi Long-term survival in patients with germ cell testicular cancer: a population-based competing-risks regression analysis
    G Gandaglia
    Cancer Prognostics and Health Outcomes Unit, University of Montreal Health Centre, Montreal, Canada Department of Urology, Urological Research Institute, Vita Salute San Raffaele University, San Raffaele Scientific Institute, Milan, Italy Electronic address
    Eur J Surg Oncol 40:103-12. 2014
    ..We sought to describe the rates of other-cancer (OCM), non-cancer related (NCRM), and cancer-specific mortality (CSM) among men with TGCT...
  40. ncbi Outcomes of radical cystectomy for transitional cell carcinoma of the bladder: a contemporary series from the Bladder Cancer Research Consortium
    Shahrokh F Shariat
    Department of Urology, University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, TX 75390, USA
    J Urol 176:2414-22; discussion 2422. 2006
    ..We present the characteristics and outcomes of a large, contemporary, consecutive series of patients treated with radical cystectomy and pelvic lymphadenectomy for transitional cell carcinoma of the bladder...
  41. ncbi A critical appraisal of logistic regression-based nomograms, artificial neural networks, classification and regression-tree models, look-up tables and risk-group stratification models for prostate cancer
    Felix K H Chun
    Cancer Prognostics and Health Outcomes Unit, University of Montreal, Montreal, Quebec, Canada
    BJU Int 99:794-800. 2007
    ..e. nomograms, look-up tables, artificial neural networks (ANN), classification and regression tree (CART) analyses and risk-group stratification (RGS) models, all of which represent valid alternatives...
  42. doi Development of a highly accurate nomogram for prediction of the need for exploration in patients with renal trauma
    Shahrokh F Shariat
    Department of Urology, University of Texas Southwestern Medical Center, Dallas, Texas, USA
    J Trauma 64:1451-8. 2008
    ..To develop and validate a nomogram for predicting the need for renal exploration after renal trauma...
  43. doi The impact of robot-assisted radical prostatectomy on the use and extent of pelvic lymph node dissection in the "post-dissemination" period
    G Gandaglia
    Cancer Prognostics and Health Outcomes Unit, University of Montreal Health Centre, Montreal, Canada Department of Urology, Urological Research Institute, Vita Salute San Raffaele University, San Raffaele Scientific Institute, Milan, Italy Electronic address
    Eur J Surg Oncol 40:1080-6. 2014
    ..The aim of our study was to re-assess the impact of robot-assisted radical prostatectomy (RARP) on the utilization rate of PLND and its extent in the post-dissemination period...
  44. pmc Accuracy of the EORTC risk tables and of the CUETO scoring model to predict outcomes in non-muscle-invasive urothelial carcinoma of the bladder
    E Xylinas
    1 Department of Urology, Weill Cornell Medical College, New York, NY, USA 2 Department of Urology, Cochin Hospital, APHP, Paris Descartes University, Paris, France
    Br J Cancer 109:1460-6. 2013
    ..The aim of the current study was to assess the performance of these predictive tools in a large multicentre cohort of NMIBC patients...
  45. doi Intensity-modulated radiation therapy leads to survival benefit only in patients with high-risk prostate cancer: a population-based study
    G Gandaglia
    Cancer Prognostics and Health Outcomes Unit, University of Montreal Health Center, Montreal, Canada
    Ann Oncol 25:979-86. 2014
    ..The aim of our study was to evaluate the survival benefit associated with IMRT in patients with PCa...
  46. doi Propensity-score matched comparison of complications, blood transfusions, length of stay, and in-hospital mortality between open and laparoscopic partial nephrectomy: a national series
    M Sun
    Cancer Prognostics and Health Outcomes Unit, University of Montreal Health Center, Hospital St Luc, 1058, rue St Denis, Montreal, Quebec, Canada H2X 3J4
    Eur J Surg Oncol 38:80-7. 2012
    ..To examine the use of open partial nephrectomy (OPN) and laparoscopic partial nephrectomy (LPN), as well as intraoperative and postoperative morbidity...
  47. ncbi French-Canadian linguistic validation of the NIH Chronic Prostatitis Symptom Index
    P I Karakiewicz
    Cancer Prognostics and Health Outcomes Unit, Montreal Health Center, Montreal, Quebec, Canada
    Can J Urol 12:2816-23. 2005
    ..However, its use is not possible in French speakers, as it has not been validated in this population. We performed a linguistic validation of the CPSI...
  48. doi [Treatment of metastatic renal cell carcinoma]
    R Thuret
    Cancer Prognostics and Health Outcomes Unit, University of Montreal Health Centre, Montreal, QC, H2X 3J4, Canada
    Prog Urol 21:233-44. 2011
    ..Phase III studies are ongoing to address the importance of CNT. This information is crucial to ensure timely delivery of a combination of medical and surgical therapies in this patient population...
  49. ncbi International validation of a preoperative nomogram for prostate cancer recurrence after radical prostatectomy
    Markus Graefen
    Department of Urology, Division of Solid Tumor Oncology, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY 10021, USA
    J Clin Oncol 20:3206-12. 2002
    ..We applied this nomogram to patients from seven different institutions spanning three continents...
  50. ncbi Tumour volume and high grade tumour volume are the best predictors of pathologic stage and biochemical recurrence after radical prostatectomy
    Felix K H Chun
    Cancer Prognostics and Health Outcomes Unit, University of Montreal Health Center CHUM, 1058, rue St Denis, Montreal, Que, Canada H2X 3J4
    Eur J Cancer 43:536-43. 2007
    ..Our goal was to examine to what extent tumour volume (TV) and percentage of high grade tumour volume (%HGTV) affect the rate of positive surgical margins and the rate of biochemical recurrence after radical prostatectomy...
  51. ncbi Development and split-sample validation of a nomogram predicting the probability of seminal vesicle invasion at radical prostatectomy
    Andrea Gallina
    Cancer Prognostics and Health Outcomes Unit, University of Montreal, Montreal, Quebec, Canada
    Eur Urol 52:98-105. 2007
    ..We hypothesized that contemporary patients, at very low risk of seminal vesicle invasion (SVI), can be highly accurately identified with an equally contemporary SVI nomogram...
  52. ncbi Patients with distant metastases from renal cell carcinoma can be accurately identified: external validation of a new nomogram
    Georg C Hutterer
    Cancer Prognostics and Health Outcomes Unit, University of Montreal Health Center, Montreal, Quebec, Canada
    BJU Int 101:39-43. 2008
    ..To identify clinical variables that can accurately predict the presence of distant metastases in patients with renal cell carcinoma (RCC)...
  53. doi Use of preoperative plasma endoglin for prediction of lymph node metastasis in patients with clinically localized prostate cancer
    Jose A Karam
    Department of Urology, The University of Texas Southwestern Medical Center, Dallas, Texas 75390 9110, USA
    Clin Cancer Res 14:1418-22. 2008
    ..The aim of the study was to evaluate whether preoperative plasma endoglin improves the prediction of lymph node metastases in patients with clinically localized prostate cancer...
  54. doi External validation of a biomarker-based preoperative nomogram predicts biochemical recurrence after radical prostatectomy
    Shahrokh F Shariat
    Cancer Prognostics and Health Outcomes Unit, University of Montreal, Montreal, Quebec, Canada
    J Clin Oncol 26:1526-31. 2008
    ..However, this model was never externally validated. We tested the accuracy of this nomogram in an independent, external cohort...
  55. doi Comparison of stage migration patterns between Europe and the USA: an analysis of 11 350 men treated with radical prostatectomy for prostate cancer
    Andrea Gallina
    Cancer Prognostics and Health Outcomes Unit, University of Montreal, Montreal, Quebec, Canada
    BJU Int 101:1513-8. 2008
    ..To examine the stage migration patterns in patients treated with radical prostatectomy (RP) for prostate cancer in Europe and in the USA in the last 20 years...
  56. doi Mortality at 120 days after prostatic biopsy: a population-based study of 22,175 men
    Andrea Gallina
    Cancer Prognostics and Health Outcomes Unit, University of Montreal, Montreal, Quebec, Canada
    Int J Cancer 123:647-52. 2008
    ..In conclusion, our data suggest that prostate biopsy might predispose to higher mortality rate. The certainty of this association remains to be proven...
  57. doi External validation of the updated partin tables in a cohort of French and Italian men
    Naeem Bhojani
    Cancer Prognostics and Health Outcomes Unit, University of Montreal, Montreal, PQ, Canada
    Int J Radiat Oncol Biol Phys 73:347-52. 2009
    ..To test the discrimination and calibration properties of the newly developed 2007 Partin Tables in two European cohorts with localized prostate cancer...
  58. doi Pre-treatment biomarker levels improve the accuracy of post-prostatectomy nomogram for prediction of biochemical recurrence
    Robert S Svatek
    Department of Urology, University of Texas Southwestern Medical Centre, 1515 Holcombe Blvd, Houston, TX 77030, USA
    Prostate 69:886-94. 2009
    ..We tested the ability of several pre-operative blood-based biomarkers to enhance the accuracy of standard post-operative features for the prediction of biochemical recurrence (BCR) after radical prostatectomy (RP)...
  59. doi The probability of Gleason score upgrading between biopsy and radical prostatectomy can be accurately predicted
    Umberto Capitanio
    Cancer Prognostics and Health Outcomes Unit, University of Montreal Health Center, Montreal, Quebec, Canada
    Int J Urol 16:526-9. 2009
    ..The current tool represents the most accurate method of predicting GSU between biopsy and RP. Nonetheless it is not perfect and its performance characteristics should be known prior to its use in clinical decision-making...
  60. doi Association of angiogenesis related markers with bladder cancer outcomes and other molecular markers
    Shahrokh F Shariat
    Department of Urology, University of Texas Southwestern Medical Center, Dallas, Texas, USA
    J Urol 183:1744-50. 2010
    ....
  61. doi Association of perioperative blood transfusion with oncologic outcomes after radical nephroureterectomy for upper tract urothelial carcinoma
    M Rieken
    Department of Urology, Weill Cornell Medical College, New York Presbyterian Hospital, New York, NY, USA Department of Urology, University Hospital Basel, Basel, Switzerland
    Eur J Surg Oncol 40:1693-9. 2014
    ..To test the hypothesis that perioperative blood transfusion (PBT)impacts oncologic outcomes of patients treated with radical nephroureterectomy (RNU) for upper tract urothelial carcinoma (UTUC)...
  62. ncbi Surgical volume is related to the rate of positive surgical margins at radical prostatectomy in European patients
    Felix K H Chun
    Cancer Prognostics and Health Outcomes Unit, University of Montreal, Montreal, Quebec, Canada
    BJU Int 98:1204-9. 2006
    ..To assess the association between surgical volume (SV) and the rate of positive surgical margins (PSM) after radical prostatectomy (RP) in a large single-institution European cohort of patients...
  63. ncbi Prognostic value of syndecan-1 expression in patients treated with radical prostatectomy
    Shahrokh F Shariat
    Department of Urology, University of Texas Southwestern Medical Center, Dallas, TX 75390 9110, USA
    BJU Int 101:232-7. 2008
    ....
  64. ncbi Cytoreductive nephron-sparing surgery does not appear to undermine disease-specific survival in patients with metastatic renal cell carcinoma
    Georg C Hutterer
    Cancer Prognostics and Health Outcomes Unit, University of Montreal Health Center, Montreal, Quebec, Canada
    Cancer 110:2428-33. 2007
    ..The disease-specific survival of patients with MRCC was compared according to the type of surgery, NSS (N=45) versus radical nephrectomy (RN) (N=732), in unmatched and matched analyses...
  65. ncbi Prostate volume and adverse prostate cancer features: fact not artifact
    Alberto Briganti
    Cancer Prognostics and Health Outcomes Unit, University of Montreal, Canada
    Eur J Cancer 43:2669-77. 2007
    ..We investigated the association between prostate size and prostate cancer grade and stage in a large (n=3412) single center radical prostatectomy cohort, which was unexposed to any form of hormonal manipulation...
  66. doi The effect of comorbidities and socioeconomic status on sexual and urinary function in men undergoing prostate cancer screening
    Naeem Bhojani
    Cancer Prognostics and Health Outcomes Unit, University of Montreal, Montreal, Quebec, Canada
    J Sex Med 5:668-76. 2008
    ..Comorbidities and socioeconomic status (SES) represent known confounders of baseline health-related quality of life...
  67. doi A nomogram predicting long-term biochemical recurrence after radical prostatectomy
    Nazareno Suardi
    Cancer Prognostics and Health Outcomes Unit, University of Montreal, Montreal, Quebec, Canada
    Cancer 112:1254-63. 2008
    ..In this report, the authors have described a model capable of predicting BCR up to at least 15 years after RP that can adjust predictions according to the disease-free interval...
  68. doi Assessment of biochemical recurrence rate in patients with pathologically confirmed insignificant prostate cancer
    Umberto Capitanio
    Cancer Prognostics and Health Outcomes Unit, University of Montreal, Montreal, QC, Canada
    Urology 72:1208-11; discussion 1212-3. 2008
    ..To examine the rate of biochemical recurrence (BCR) in patients with pathologically confirmed insignificant prostate cancer (PIPCa)...
  69. doi An updated catalog of prostate cancer predictive tools
    Shahrokh F Shariat
    Department of Urology, The University of Texas Southwestern Medical Center, Dallas, Texas 75390, USA
    Cancer 113:3075-99. 2008
    ..Nevertheless, many more predictive tools, comparisons between them, and improvements to existing tools are needed...
  70. doi Comparison of oncologic outcomes for open and laparoscopic nephroureterectomy: a multi-institutional analysis of 1249 cases
    Umberto Capitanio
    Cancer Prognostics and Health Outcomes Unit, University of Montreal Health Center, Montreal, Quebec, Canada
    Eur Urol 56:1-9. 2009
    ..Data regarding the oncologic efficacy of laparoscopic nephroureterectomy (LNU) compared to open nephroureterectomy (ONU) are scarce...
  71. doi Combination of multiple molecular markers can improve prognostication in patients with locally advanced and lymph node positive bladder cancer
    Shahrokh F Shariat
    Department of Urology, University of Texas Southwestern Medical Center, Dallas, Texas 10065, USA
    J Urol 183:68-75. 2010
    ..We also assessed whether the combination of molecular markers is superior to any individual biomarker...
  72. doi A population-based comparison of cancer-control rates between radical and partial nephrectomy for T1A renal cell carcinoma
    Maxime Crepel
    Cancer Prognostics and Health Outcomes Unit, University of Montreal, Montreal, Quebec, Canada
    Urology 76:883-8. 2010
    ..We relied on the surveillance, epidemiology, and end results (SEER) database and assessed cancer-specific mortality (CSM) after either PN or RN for T1aN0M0 RCC, in competing-risks models...
  73. pmc Risk stratification of pT1-3N0 patients after radical cystectomy for adjuvant chemotherapy counselling
    E Xylinas
    Department of Urology, Weill Cornell Medical College, Starr 900, 525 East 68th Street, Box 94, New York, NY 10065, USA
    Br J Cancer 107:1826-32. 2012
    ..In pT1-T3N0 urothelial carcinoma of the bladder (UCB) patients, multi-modal therapy is inconsistently recommended. The aim of the study was to develop a prognostic tool to help decision-making regarding adjuvant therapy...
  74. doi Partin Tables cannot accurately predict the pathological stage at radical prostatectomy
    N Bhojani
    Cancer Prognostics and Health Outcomes Unit, University of Montreal Health Center CHUM, Montreal, Quebec, Canada
    Eur J Surg Oncol 35:123-8. 2009
    ..The Partin Tables' predictions are used to guide the type (nerve preserving RP) and/or the extent (RP with wide resection) of RP. We examined the ability of the Partin Tables' predictions incorrectly assigning the stage at RP...
  75. ncbi Assessment of the enhancement in predictive accuracy provided by systematic biopsy in predicting outcome for clinically localized prostate cancer
    Markus Graefen
    Department of Urology, Memorial Sloan Kettering Cancer Center, New York, New York, USA
    J Urol 171:200-3. 2004
    ..We investigated whether the addition of prostate biopsy features may enhance the accuracy of a nomogram predicting recurrence after radical prostatectomy (RP)...
  76. ncbi Prostate cancer nomograms: an update
    Felix K H Chun
    Cancer Prognostics and Health Outcomes Unit, University of Montreal, Montreal, QC, Canada
    Eur Urol 50:914-26; discussion 926. 2006
    ..Several nomograms have been developed to predict outcomes related to prostate cancer (PCa)...
  77. ncbi Nomogram for predicting disease recurrence after radical cystectomy for transitional cell carcinoma of the bladder
    Pierre I Karakiewicz
    Cancer Prognostics and Health Outcomes Unit, University of Montreal, Montreal, Quebec, Canada
    J Urol 176:1354-61; discussion 1361-2. 2006
    ....
  78. ncbi Caveolin-1 overexpression is associated with aggressive prostate cancer recurrence
    Jose A Karam
    Department of Urology, University of Texas Southwestern Medical Center, Dallas, TX 75390 9110, USA
    Prostate 67:614-22. 2007
    ....
  79. ncbi A nomogram predicting 10-year life expectancy in candidates for radical prostatectomy or radiotherapy for prostate cancer
    Jochen Walz
    Cancer Prognostics and Health Outcomes Unit, University of Montreal Health Center, Montreal, Quebec, Canada
    J Clin Oncol 25:3576-81. 2007
    ..To circumvent this problem, we developed a nomogram predicting 10-year LE for patients treated with either radical prostatectomy (RP) or external-beam radiation therapy (EBRT) and compared it with an existing tool...
  80. doi Nephrectomy improves the survival of patients with locally advanced renal cell carcinoma
    Laurent Zini
    Cancer Prognostics and Health Outcomes Unit, University of Montreal Health Center, Montreal, Quebec, Canada
    BJU Int 102:1610-4. 2008
    ..To examine the cancer-specific survival of patients treated with nephrectomy and compared it to that of patients managed without surgery...
  81. doi Percent free prostate-specific antigen (PSA) is an accurate predictor of prostate cancer risk in men with serum PSA 2.5 ng/mL and lower
    Jochen Walz
    Cancer Prognostics and Health Outcomes Unit, University of Montreal, Montreal, Quebec, Canada
    Cancer 113:2695-703. 2008
    ..Because identification of these patients represents a difficult task, we assessed the ability of percent free PSA to discriminate between benign and malignant prostate biopsy outcomes in men with PSA < or =2.5 ng/mL...
  82. doi Predictive value of plasma hepatocyte growth factor/scatter factor levels in patients with clinically localized prostate cancer
    Amit Gupta
    Department of Urology, The University of Texas Southwestern Medical Center, Dallas, Texas 75390 9110, USA
    Clin Cancer Res 14:7385-90. 2008
    ..We assessed whether preoperative plasma levels of HGF can enhance the accuracy of standard models for predicting pathologic features and clinical outcomes...
  83. doi Baseline renal function, ischaemia time and blood loss predict the rate of renal failure after partial nephrectomy
    Claudio Jeldres
    Cancer Prognostics and Health Outcomes Unit, University of Montreal, Montreal, Canada
    BJU Int 103:1632-5. 2009
    ..To identify independent predictors of renal failure after partial nephrectomy (PN) in patients with renal cell carcinoma (RCC)...
  84. doi Nephroureterectomy and segmental ureterectomy in the treatment of invasive upper tract urothelial carcinoma: a population-based study of 2299 patients
    Giovanni Lughezzani
    Cancer Prognosis and Health Outcomes Unit, University of Montreal Health Center, Montreal, QC, Canada, H2X 3J4
    Eur J Cancer 45:3291-7. 2009
    ..We tested the prognostic impact of pT and pN stages on cancer-specific mortality (CSM) in a large population-based cohort of surgically treated patients with UTUC...
  85. doi Can renal mass biopsy assessment of tumor grade be safely substituted for by a predictive model?
    Claudio Jeldres
    Department of Urology, University of Montreal, Montreal, Quebec, Canada
    J Urol 182:2585-9. 2009
    ..To date the best available model has shown poor accuracy (55.6%), which is close to flipping a coin (50%) and clearly inadequate for use in clinical practice...
  86. doi A nomogram predicting prostate cancer-specific mortality after radical prostatectomy
    Christopher R Porter
    Department of Urology, Virginia Mason Medical Center, Seattle, Wash, USA
    Urol Int 84:132-40. 2010
    ..We describe a model capable of predicting prostate cancer (PCa)-specific mortality up to 20 years after a radical prostatectomy (RP), which can adjust the predictions according to disease-free interval...
  87. doi The prognostic value of erythrocyte polyamines in the preoperative evaluation of patients with renal cell carcinoma
    Giovanni Lughezzani
    Cancer Prognostics and Health Outcomes Unit, University of Montreal Health Center, Montreal, QC, Canada
    Eur J Cancer 46:1927-35. 2010
    ..We tested whether spermine and spermidine could improve the prognostic ability of six established preoperative predictors of cancer-specific mortality (CSM) after partial or radical nephrectomy for renal cell carcinoma (RCC)...
  88. ncbi Validation of NF-kappaB p65 as a prostate cancer prognostic marker on a large cohort of European patients
    L Lessard
    Centre de Recherche du CHUM, Montreal, QC, Canada Hôpital du Sacré Coeur de Montréal, Montreal, QC, Canada University Medical Center Hamburg Eppendorf, Hamburg, Germany
    J Clin Oncol 26:11055. 2008
    ..We and others have shown that the nuclear expression of p65 can predict biochemical recurrence and lymph node invasion in small cohorts (i.e. < 100 patients)...
  89. doi Influence of low-molecular-weight heparin dosage on red blood cell transfusion, lymphocele rate and drainage duration after open radical prostatectomy
    J Schmitges
    Martini Clinic, Prostate Cancer Center Hamburg Eppendorf, Hamburg, Germany
    Eur J Surg Oncol 38:1082-8. 2012
    ..To assess the rates of red blood cell (RBC) transfusions, pelvic lymphoceles, and prolonged drainage duration in patients after radical prostatectomy (RP) receiving perioperative bridging with low-molecular-weight heparin (LMWH)...
  90. ncbi Unclassified renal cell carcinoma: an analysis of 85 cases
    Pierre I Karakiewicz
    Cancer Prognostics and Health Outcomes Unit, University of Montreal Health Center, Montreal, Quebec, Canada
    BJU Int 100:802-8. 2007
    ..To compare cancer-specific mortality in patients with unclassified renal cell carcinoma (URCC) vs clear cell RCC (CRCC) after nephrectomy, as URCC is a rare but very aggressive histological subtype...
  91. doi Independent validation of a model predicting the need for packed red blood cell transfusion at liver transplantation
    Luc Massicotte
    Department of Anesthesiology, Centre Hospitalier de l Universite de Montreal CHUM, Hôpital St Luc, Montreal, QC, Canada
    Transplantation 88:386-91. 2009
    ..Moreover, the nomogram was validated in an independent cohort of 109 prospectively gathered OLTs...
  92. ncbi Residual pathologic stage at radical cystectomy and risk stratification of patients with pT2N0 bladder cancer
    H Isbarn
    University of Montreal, Montreal, QC, Canada Texas Oncology, Baylor College of Medicine, Houston, TX Memorial Sloan Kettering Cancer Center, New York, NY University of Rochester, Rochester, NY University of Texas Southwestern, Dallas, TX Johns Hopkins Hospital, Baltimore, MD Baylor College of Medicine, Houston, TX
    J Clin Oncol 27:5076. 2009
    ..Patients with high-risk pT2N0 disease may be candidates for trials of adjuvant therapy...
  93. ncbi Prognostic factors of cancer recurrence and progression in non-muscle-invasive urothelial carcinoma: A multicenter study of over 4,300 patients
    T F Chromecki
    Weill Cornell Medical College, New York, NY University of Texas M D Anderson Cancer Center, Houston, TX Sahlgrenska University Hospital, Goteborg, Sweden Cancer Prognostics and Health Outcomes Unit, University of Montreal Health Center, Montreal, QC, Canada
    J Clin Oncol 29:249. 2011
    ..The aim of our study was to identify prognostic factors of cancer recurrence and progression in patients with primary UCB...
  94. doi Adherence of the indication to European Association of Urology guideline recommended pelvic lymph node dissection at a high-volume center: Differences between open and robot-assisted radical prostatectomy
    J Schiffmann
    Martini Clinic, Prostate Cancer Center Hamburg Eppendorf, Hamburg, Germany Cancer Prognostics and Health Outcomes Unit, University of Montreal Health Center, Montreal, Canada Electronic address
    Eur J Surg Oncol 41:1547-53. 2015
    ..To assess guideline recommended and observed PLND rates in a high-volume center cohort...
  95. ncbi Comparative evaluation of total PSA, free/total PSA, and complexed PSA in prostate cancer detection
    S Tanguay
    Department of Surgery Urology, McGill University, Montreal, Quebec, Canada
    Urology 59:261-5. 2002
    ..To compare the performance of prostate-specific antigen (PSA), the free/total PSA (F/T PSA) ratio, and complexed PSA (cPSA) in prostate cancer detection...
  96. ncbi Adjuvant chemotherapy for high-risk upper tract urothelial carcinoma: Results from the Upper Tract Urothelial Carcinoma Collaboration
    N Hellenthal
    University of California, Davis, Sacramento, CA University of Texas Southwestern, Dallas, TX University of Texas M D Anderson Cancer Center, Houston, TX University of Montreal, Montreal, QC, Canada Vita Salute University, Milan, Italy Universitätsklinikum Mannheim, Mannheim, Germany University of Vienna, Vienna, Austria University of Michigan, Ann Arbor, MI Medical University Graz, Graz, Austria
    J Clin Oncol 27:5075. 2009
    ..Our goal was to determine the incidence of receipt of adjuvant chemotherapy in high-risk patients and the ensuing effect on overall- and cancer-specific survival...
  97. ncbi Tissue-based molecular markers for bladder cancer
    C E Barbieri
    Department of Urology, Weill Cornell Medical Center, New York, NY, USA
    Minerva Urol Nefrol 62:241-58. 2010
    ..A combination of complementary and yet independent molecular markers will likely better capture the biologic potential of each individual bladder tumor resulting in improved clinical decision-making...
  98. ncbi Percent free prostate specific antigen is not an independent predictor of organ confinement or prostate specific antigen recurrence in unscreened patients with localized prostate cancer treated with radical prostatectomy
    Markus Graefen
    Department of Urology, University Hospital Hamburg Eppendorf, Germany
    J Urol 167:1306-9. 2002
    ..We studied the controversial relationship of percent free prostate specific antigen (PSA) with organ confined prostate cancer and PSA failure after radical prostatectomy...
  99. ncbi Assessment of clinical and pathologic characteristics predisposing to disease recurrence following radical prostatectomy in men with pathologically organ-confined prostate cancer
    R Jüri Palisaar
    Department of Urology, University Hospital Hamburg Eppendorf, Hamburg, Germany
    Eur Urol 41:155-61. 2002
    ..To identify risk factors for biochemical failure after radical prostatectomy (RP) in men with pathologically organ-confined (OC) prostate cancer (PCa)...
  100. ncbi A validation of two preoperative nomograms predicting recurrence following radical prostatectomy in a cohort of European men
    Markus Graefen
    Departments of Urology and Pathology, University Hospital, Hamburg Eppendorf, Germany
    Urol Oncol 7:141-6. 2002
    ..The high predictive accuracy of both nomograms demonstrates that these predictive tools derived in the U.S. can be applied to non-U.S. patients...