Hadas D Fischer

Summary

Affiliation: Institute for Clinical Evaluative Sciences
Country: Canada

Publications

  1. doi request reprint Hemorrhage during warfarin therapy associated with cotrimoxazole and other urinary tract anti-infective agents: a population-based study
    Hadas D Fischer
    Department of Health Policy Management and Evaluation, University of Toronto, Toront, Ontario, Canada
    Arch Intern Med 170:617-21. 2010
  2. doi request reprint Older men with dementia are at greater risk than women of serious events after initiating antipsychotic therapy
    Paula A Rochon
    Women s College Research Institute, Women s College Hospital, Toronto, Ontario, Canada
    J Am Geriatr Soc 61:55-61. 2013
  3. doi request reprint Lithium Use in Older Adults is Associated with Increased Prescribing of Parkinson Medications
    Connie Marras
    Morton and Gloria Shulman Movement Disorders Centre, Toronto Western Hospital and The Edmond J Safra Program in Parkinson s Disease, Toronto, Ontario, Canada University of Toronto, Toronto, Ontario, Canada Electronic address
    Am J Geriatr Psychiatry 24:301-9. 2016
  4. doi request reprint Use of clarithromycin and adverse cardiovascular events among older patients receiving donepezil: a population-based, nested case-control study
    Janine R Hutson
    Faculty of Medicine, University of Toronto, Toronto, ON, Canada
    Drugs Aging 29:205-11. 2012
  5. doi request reprint Antipsychotic drugs and the risk of hyperglycemia in older adults without diabetes: a population-based observational study
    Lorraine L Lipscombe
    Institute for Clinical Evaluative Sciences, Toronto, Ontario, Canada
    Am J Geriatr Psychiatry 19:1026-33. 2011
  6. doi request reprint Inhaled Long-acting Anticholinergics and Urinary Tract Infection in Individuals with COPD
    Andrea S Gershon
    a Sunnybrook Research Institute, Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada
    COPD 14:105-112. 2017
  7. pmc Incident opioid drug use among older adults with chronic obstructive pulmonary disease: a population-based cohort study
    Nicholas T Vozoris
    Division of Respirology, Department of Medicine, St Michael s Hospital, Toronto, Ontario, Canada
    Br J Clin Pharmacol 81:161-70. 2016
  8. doi request reprint Incident opioid drug use and adverse respiratory outcomes among older adults with COPD
    Nicholas T Vozoris
    Division of Respirology, Department of Medicine, St Michael s Hospital, Toronto, ON, Canada Keenan Research Centre in the Li Ka Shing Knowledge Institute, St Michael s Hospital, Toronto, ON, Canada Dept of Medicine, University of Toronto, Toronto, ON, Canada
    Eur Respir J 48:683-93. 2016
  9. doi request reprint Demographic characteristics and healthcare use of centenarians: a population-based cohort study
    Paula A Rochon
    Women s College Research Institute, Women s College Hospital, Toronto, Ontario, Canada Department of Medicine, University of Toronto, Toronto, Ontario, Canada Institute of Health Policy, Management and Evaluation, University of Toronto, Toronto, Ontario, Canada Institute for Clinical Evaluative Sciences, Toronto, Ontario, Canada
    J Am Geriatr Soc 62:86-93. 2014
  10. doi request reprint Prolonged antibiotic treatment in long-term care: role of the prescriber
    Nick Daneman
    Division of Infectious Diseases, Department of Medicine, SunnybrookHealth Sciences Centre, University of Toronto, Toronto, Canada
    JAMA Intern Med 173:673-82. 2013

Collaborators

Detail Information

Publications31

  1. doi request reprint Hemorrhage during warfarin therapy associated with cotrimoxazole and other urinary tract anti-infective agents: a population-based study
    Hadas D Fischer
    Department of Health Policy Management and Evaluation, University of Toronto, Toront, Ontario, Canada
    Arch Intern Med 170:617-21. 2010
    ..We examined the risk of upper gastrointestinal (UGI) tract hemorrhage in older patients receiving warfarin in combination with antibiotics commonly used to treat urinary tract infection, with a focus on cotrimoxazole...
  2. doi request reprint Older men with dementia are at greater risk than women of serious events after initiating antipsychotic therapy
    Paula A Rochon
    Women s College Research Institute, Women s College Hospital, Toronto, Ontario, Canada
    J Am Geriatr Soc 61:55-61. 2013
    ..To understand how drug therapy differently affects older women and men...
  3. doi request reprint Lithium Use in Older Adults is Associated with Increased Prescribing of Parkinson Medications
    Connie Marras
    Morton and Gloria Shulman Movement Disorders Centre, Toronto Western Hospital and The Edmond J Safra Program in Parkinson s Disease, Toronto, Ontario, Canada University of Toronto, Toronto, Ontario, Canada Electronic address
    Am J Geriatr Psychiatry 24:301-9. 2016
    ....
  4. doi request reprint Use of clarithromycin and adverse cardiovascular events among older patients receiving donepezil: a population-based, nested case-control study
    Janine R Hutson
    Faculty of Medicine, University of Toronto, Toronto, ON, Canada
    Drugs Aging 29:205-11. 2012
    ..Donepezil is metabolized by the cytochrome P450 isozyme 3A4 (CYP3A4). Clarithromycin is a potent inhibitor of CYP3A4, and patients taking both of these drugs may be at increased risk of cardiac adverse events...
  5. doi request reprint Antipsychotic drugs and the risk of hyperglycemia in older adults without diabetes: a population-based observational study
    Lorraine L Lipscombe
    Institute for Clinical Evaluative Sciences, Toronto, Ontario, Canada
    Am J Geriatr Psychiatry 19:1026-33. 2011
    ..To determine whether current antipsychotic use among older persons without diabetes is associated with a higher risk of hospital visits for hyperglycemia, as previous studies in this population have yielded conflicting results...
  6. doi request reprint Inhaled Long-acting Anticholinergics and Urinary Tract Infection in Individuals with COPD
    Andrea S Gershon
    a Sunnybrook Research Institute, Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada
    COPD 14:105-112. 2017
    ..In conclusion, older men with COPD newly started on LAA are at increased risk of UTI. Men considering an inhaled LAA should be informed of this risk and, if they decide to take it, be provided with appropriate monitoring...
  7. pmc Incident opioid drug use among older adults with chronic obstructive pulmonary disease: a population-based cohort study
    Nicholas T Vozoris
    Division of Respirology, Department of Medicine, St Michael s Hospital, Toronto, Ontario, Canada
    Br J Clin Pharmacol 81:161-70. 2016
    ..The purpose of the present study was to describe the scope, pattern and patient characteristics associated with incident opioid use among older adults with chronic obstructive pulmonary disease (COPD)...
  8. doi request reprint Incident opioid drug use and adverse respiratory outcomes among older adults with COPD
    Nicholas T Vozoris
    Division of Respirology, Department of Medicine, St Michael s Hospital, Toronto, ON, Canada Keenan Research Centre in the Li Ka Shing Knowledge Institute, St Michael s Hospital, Toronto, ON, Canada Dept of Medicine, University of Toronto, Toronto, ON, Canada
    Eur Respir J 48:683-93. 2016
    ..Potential adverse respiratory outcomes should be considered when prescribing new opioids in this population. ..
  9. doi request reprint Demographic characteristics and healthcare use of centenarians: a population-based cohort study
    Paula A Rochon
    Women s College Research Institute, Women s College Hospital, Toronto, Ontario, Canada Department of Medicine, University of Toronto, Toronto, Ontario, Canada Institute of Health Policy, Management and Evaluation, University of Toronto, Toronto, Ontario, Canada Institute for Clinical Evaluative Sciences, Toronto, Ontario, Canada
    J Am Geriatr Soc 62:86-93. 2014
    ..To better understand how centenarians use the healthcare system as an important step toward improving their service delivery...
  10. doi request reprint Prolonged antibiotic treatment in long-term care: role of the prescriber
    Nick Daneman
    Division of Infectious Diseases, Department of Medicine, SunnybrookHealth Sciences Centre, University of Toronto, Toronto, Canada
    JAMA Intern Med 173:673-82. 2013
    ..Given that most common bacterial infections can be treated with antibiotic courses of 7 or fewer days, reducing standard antibiotic treatment durations may be an avenue to curtailing antibiotic overuse in long-term care...
  11. doi request reprint Current prescription patterns and safety profile of irreversible monoamine oxidase inhibitors: a population-based cohort study of older adults
    Kenneth I Shulman
    Department of Psychiatry, Sunnybrook Health Sciences Centre, Toronto, Ontario, M4N 3M5, Canada
    J Clin Psychiatry 70:1681-6. 2009
    ..To determine the prescription pattern and safety profile for irreversible monoamine oxidase inhibitors (MAOIs) in older adults over the past decade...
  12. doi request reprint Benzodiazepine drug use and adverse respiratory outcomes among older adults with COPD
    Nicholas T Vozoris
    Division of Respirology, Dept of Medicine, St Michael s Hospital, Toronto, ON, Canada Dept of Medicine, University of Toronto, Toronto, ON, Canada Dept of Medicine, Queen s University, Kingston, ON, Canada
    Eur Respir J 44:332-40. 2014
    ..The findings suggest that decisions to use benzodiazepines in older patients with COPD need to consider potential adverse respiratory outcomes. ..
  13. doi request reprint Management of neuropsychiatric symptoms in long-term care residents with Parkinson's disease: a retrospective cohort study
    Nathan Herrmann
    Department of Psychiatry, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, ON, Canada
    Drugs Aging 30:19-22. 2013
    ....
  14. doi request reprint Atypical antipsychotic use and parkinsonism in dementia: effects of drug, dose, and sex
    Connie Marras
    Morton and Gloria Shulman Movement Disorders Centre, Toronto Western Hospital, Toronto, Ontario, Canada
    Am J Geriatr Pharmacother 10:381-9. 2012
    ..There is a particular paucity of information on this in real-world use of these drugs, outside of clinical trial settings...
  15. doi request reprint Syncope and its consequences in patients with dementia receiving cholinesterase inhibitors: a population-based cohort study
    Sudeep S Gill
    Institute for Clinical Evaluative Sciences, Toronto, Ontario, Canada
    Arch Intern Med 169:867-73. 2009
    ..These drugs can provoke symptomatic bradycardia and syncope, which may lead to permanent pacemaker insertion. Drug-induced syncope may also precipitate fall-related injuries, including hip fracture...
  16. doi request reprint Variability in Antibiotic Use Across Nursing Homes and the Risk of Antibiotic-Related Adverse Outcomes for Individual Residents
    Nick Daneman
    Institute for Clinical Evaluative Sciences, Toronto, Ontario, Canada2Division of Infectious Diseases, Department of Medicine, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, Ontario, Canada3Institute of Health Policy, Management and Eva
    JAMA Intern Med 175:1331-9. 2015
    ..Antibiotics are frequently and often inappropriately prescribed to patients in nursing homes. These antibiotics pose direct risks to recipients and indirect risks to others residing in the home...
  17. pmc Serious events in older Ontario residents receiving bowel preparations for outpatient colonoscopy with various comorbidity profiles: a descriptive, population-based study
    Joanne Man Wai Ho
    University of Toronto, Toronto, Ontario, Canada
    Can J Gastroenterol 26:436-40. 2012
    ..Little is known about adverse events associated with these preparations, particularly in older patients or patients with medical comorbidities...
  18. doi request reprint Breast Cancer Therapy-Related Cardiac Dysfunction in Adult Women Treated in Routine Clinical Practice: A Population-Based Cohort Study
    Paaladinesh Thavendiranathan
    Paaladinesh Thavendiranathan and Douglas S Lee, Peter Munk Cardiac Centre and the Ted Rogers Program in Cardiotoxicity Prevention, University Health Network, Toronto General Hospital, University of Toronto Husam Abdel Qadir, Women s College Hospital Hadas D Fischer, Ximena Camacho, Peter C Austin, and Douglas S Lee, Institute for Clinical Evaluative Sciences and Eitan Amir, Princess Margaret Cancer Centre, University of Toronto, Toronto, Ontario, Canada
    J Clin Oncol 34:2239-46. 2016
    ..We sought to determine the risk of cardiotoxicity with breast cancer therapy in women with an age distribution representative of routine clinical practice...
  19. doi request reprint Antibiotic use in long-term care facilities
    Nick Daneman
    Institute for Clinical Evaluative Sciences, Toronto, Ontario, Canada
    J Antimicrob Chemother 66:2856-63. 2011
    ..Our goal was to examine the prevalence of antibiotic use among long-term care facility residents and the extent of variability across these institutions...
  20. doi request reprint The risk of myocardial infarction with aromatase inhibitors relative to tamoxifen in post-menopausal women with early stage breast cancer
    Husam Abdel-Qadir
    Department of Medicine, University of Toronto, Suite RFE 3 805, 200 Elizabeth Street, M5G 2C4, Toronto, Ontario, Canada Institute for Clinical Evaluative Sciences, G1 06, 2075 Bayview Ave, M4N 3M5, Toronto, Ontario, Canada Institute of Health Policy, Management and Evaluation, University of Toronto, 155 College Street, Suite 425, M5T 3M6, Toronto, Ontario, Canada Women s College Hospital, 76 Grenville Street, M5S1B2, Toronto, Ontario, Canada
    Eur J Cancer 68:11-21. 2016
    ..Aromatase inhibitors (AIs) may increase cardiovascular risk relative to tamoxifen in post-menopausal women with breast cancer. This risk has not been well-quantified outside of clinical trials...
  21. doi request reprint Current psychotropic medication prescribing patterns in late-life bipolar disorder
    Soham Rej
    Division of Geriatric Psychiatry, Department of Psychiatry, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, Canada
    Int J Geriatr Psychiatry . 2016
    ..Our objective was to describe current psychotropic prescribing patterns in a large Canadian late-life bipolar sample...
  22. pmc Potential savings of harmonising hospital and community formularies for chronic disease medications initiated in hospital
    Lauren Lapointe-Shaw
    Department of Medicine, University of Toronto, Toronto, Ontario
    PLoS ONE 7:e39737. 2012
    ..We sought to determine how much public money could be saved on chronic medications if hospitals promoted the initiation of agents with the lowest outpatient formulary prices...
  23. doi request reprint Association between tamoxifen treatment and diabetes: a population-based study
    Lorraine L Lipscombe
    Women s College Hospital, Toronto, Canada
    Cancer 118:2615-22. 2012
    ..Tamoxifen may increase diabetes incidence through its estrogen-inhibiting effects. This study assessed whether tamoxifen treatment in older breast cancer survivors is associated with an increased risk of diabetes...
  24. pmc Unplanned readmissions after hospital discharge among patients identified as being at high risk for readmission using a validated predictive algorithm
    Andrea Gruneir
    Women s College Research Institute, University of Toronto, Canada
    Open Med 5:e104-11. 2011
    ..The purpose of this study was to describe medical patients identified using a recently published and validated algorithm (the LACE index) as being at high risk for readmission and to examine their actual hospital readmission rates...
  25. pmc Time to follow-up of an abnormal mammogram in women with diabetes: a population-based study
    Syed Yaser Habeeb
    Department of Medicine, University of Toronto, Toronto, Canada
    Cancer Med 5:3292-3299. 2016
    ..The results of this study suggest that diagnostic delays after screening do not significantly contribute to higher breast cancer mortality in women with diabetes...
  26. pmc Anticholinergic Drug Burden in Persons with Dementia Taking a Cholinesterase Inhibitor: The Effect of Multiple Physicians
    Christina E Reppas-Rindlisbacher
    Women s College Research Institute, Women s College Hospital, Toronto, Ontario, Canada
    J Am Geriatr Soc 64:492-500. 2016
    ..To explore the association between the number of physicians providing care and anticholinergic drug burden in older persons newly initiated on cholinesterase inhibitor therapy for the management of dementia...
  27. pmc Levothyroxine dose and risk of fractures in older adults: nested case-control study
    Marci R Turner
    Department of Medicine, University of Toronto, Canada
    BMJ 342:d2238. 2011
    ..To quantify the effect of levothyroxine dose on risk of fractures in older adults...
  28. doi request reprint The temporal relationship between diabetes and cancer: A population-based study
    Iliana C Lega
    Women s College Research Institute, University of Toronto, Toronto, Ontario, Canada
    Cancer 122:2731-8. 2016
    ..The goal of the current study was to explore the temporal relationship between diabetes and cancer incidence...
  29. pmc Rehospitalizations and Emergency Department Visits after Hospital Discharge in Patients Receiving Maintenance Hemodialysis
    Ziv Harel
    Division of Nephrology, St Michael s Hospital, University of Toronto, Toronto, Ontario, Canada Li Ka Shing Knowledge Institute, St Michael s Hospital, Toronto, Ontario, Canada Institute for Clinical Evaluative Sciences, Toronto, Ontario, Canada
    J Am Soc Nephrol 26:3141-50. 2015
    ..A focus on improving care transitions from the inpatient setting to the outpatient dialysis unit may improve outcomes and reduce healthcare costs. ..
  30. pmc Unintentional Discontinuation of Chronic Medications for Seniors in Nursing Homes: Evaluation of a National Medication Reconciliation Accreditation Requirement Using a Population-Based Cohort Study
    Nathan M Stall
    From the Department of Medicine NMS, EE, CMB, University of Toronto Institute for Clinical and Evaluative Sciences HDF, ASB, S Bronskill, MMM, PR, DRU, CFW, CMB Keenan Research Centre ASB, MMM, Li Ka Shing Knowledge Institute, St Michael s Hospital Institute of Health Policy, Management and Evaluation ASB, S Bronskill, EE, PR, DRU, CMB Lawrence S Bloomberg Faculty of Nursing ASB, University of Toronto Health Quality Ontario S Brener Department of Pharmacy OF, University Health Network Leslie Dan Faculty of Pharmacy OF, MMM, University of Toronto Division of General Internal Medicine DL, CMB, Mount Sinai Hospital Women s College Research Institute PR, Women s College Hospital and Department of Surgery DRU, University of Toronto, Toronto, Canada
    Medicine (Baltimore) 94:e899. 2015
    ..This change was not directly associated with the new medication reconciliation accreditation requirement, but the overall improvements observed may have been reflective of multiple processes and not 1 individual intervention. ..
  31. doi request reprint Antipsychotic drugs and hyperglycemia in older patients with diabetes
    Lorraine L Lipscombe
    Institute for Clinical Evaluative Sciences, Toronto, Ontario, Canada
    Arch Intern Med 169:1282-9. 2009
    ..Evidence suggests that there is an association between antipsychotic drugs and new-onset diabetes, but little is known about the risk of hyperglycemia among persons with preexisting diabetes...