Philippe Goffaux

Summary

Country: Canada

Publications

  1. doi request reprint Individual differences in pain sensitivity vary as a function of precuneus reactivity
    Philippe Goffaux
    Departement de Chirurgie, Neurochirurgie, Faculte de Medecine, Universite de Sherbrooke, 3001, 12e Avenue Nord, Sherbrooke, QC, J1H 5N4, Canada
    Brain Topogr 27:366-74. 2014
  2. doi request reprint Brain tumor headaches: from bedside to bench
    Philippe Goffaux
    Department of Neurosurgery and Neuro Oncology, Universite de Sherbrooke, Faculty of Medicine, Sherbrooke, Quebec, Canada
    Neurosurgery 67:459-66. 2010
  3. doi request reprint Sex differences in perceived pain are affected by an anxious brain
    Philippe Goffaux
    Universite de Sherbrooke, Faculte de Medecine, Sherbrooke, Quebec, Canada
    Pain 152:2065-73. 2011
  4. doi request reprint Pain relief through expectation supersedes descending inhibitory deficits in fibromyalgia patients
    Philippe Goffaux
    Universite de Sherbrooke, Faculte de Medecine, Neurochirurgie, 3001, 12e Avenue Nord, Sherbrooke, Que, Canada J1H 5N4
    Pain 145:18-23. 2009
  5. doi request reprint Respiratory effects on experimental heat pain and cardiac activity
    Philippe Chalaye
    Universite de Sherbrooke, Faculte de Medecine, Sherbrooke, Quebec, Canada
    Pain Med 10:1334-40. 2009
  6. doi request reprint The deficit of pain inhibition in fibromyalgia is more pronounced in patients with comorbid depressive symptoms
    Juliana Barcellos de Souza
    Faculte de Medecine et des Sciences de la Sante, Universite de Sherbrooke, Sherbrooke, Canada
    Clin J Pain 25:123-7. 2009
  7. doi request reprint Fibromyalgia subgroups: profiling distinct subgroups using the Fibromyalgia Impact Questionnaire. A preliminary study
    Juliana Barcellos de Souza
    Faculte de Medecine et des Sciences de la Sante, Universite de Sherbrooke, Axe Douleur CRC CHUS, 3001, Sherbrooke, QC, Canada
    Rheumatol Int 29:509-15. 2009
  8. doi request reprint Quality of life in neurooncology--age matters
    Nadia Veilleux
    Department of Neurosurgery and Neuro Oncology, Faculty of Medicine, Universite de Sherbrooke, Quebec, Canada
    J Neurosurg 113:325-32. 2010
  9. doi request reprint Pain perception in schizophrenia: evidence of a specific pain response profile
    Mylène Lévesque
    Departement de Neurochirurgie, Faculte de Medecine et des Sciences de la Sante, Universite de Sherbrooke, Sherbrooke, Canada
    Pain Med 13:1571-9. 2012
  10. doi request reprint Evidence of descending inhibition deficits in atypical but not classical trigeminal neuralgia
    Guillaume Leonard
    Universite de Sherbrooke, Faculte de Medecine, Quebec, Canada
    Pain 147:217-23. 2009

Collaborators

Detail Information

Publications30

  1. doi request reprint Individual differences in pain sensitivity vary as a function of precuneus reactivity
    Philippe Goffaux
    Departement de Chirurgie, Neurochirurgie, Faculte de Medecine, Universite de Sherbrooke, 3001, 12e Avenue Nord, Sherbrooke, QC, J1H 5N4, Canada
    Brain Topogr 27:366-74. 2014
    ..Importantly, the precuneus did not contribute to the actual representation of pain in the brain, suggesting that pain sensitivity and pain representation depend on separate neuronal sub-systems. ..
  2. doi request reprint Brain tumor headaches: from bedside to bench
    Philippe Goffaux
    Department of Neurosurgery and Neuro Oncology, Universite de Sherbrooke, Faculty of Medicine, Sherbrooke, Quebec, Canada
    Neurosurgery 67:459-66. 2010
    ..The following sections review these generalizations, presenting caveats where appropriate. Lingering questions in the field are also addressed and presented together with promising future research avenues...
  3. doi request reprint Sex differences in perceived pain are affected by an anxious brain
    Philippe Goffaux
    Universite de Sherbrooke, Faculte de Medecine, Sherbrooke, Quebec, Canada
    Pain 152:2065-73. 2011
    ..In our study, the mediating role of anxiety on sex differences in pain was tested and confirmed using path analysis...
  4. doi request reprint Pain relief through expectation supersedes descending inhibitory deficits in fibromyalgia patients
    Philippe Goffaux
    Universite de Sherbrooke, Faculte de Medecine, Neurochirurgie, 3001, 12e Avenue Nord, Sherbrooke, Que, Canada J1H 5N4
    Pain 145:18-23. 2009
    ..These results indicate that FMs are capable of expectancy-induced analgesia but that, for them, this form of analgesia does not depend on the recruitment of descending inhibitory projections...
  5. doi request reprint Respiratory effects on experimental heat pain and cardiac activity
    Philippe Chalaye
    Universite de Sherbrooke, Faculte de Medecine, Sherbrooke, Quebec, Canada
    Pain Med 10:1334-40. 2009
    ..Slow deep breathing has been proposed as an effective method to decrease pain. However, experimental studies conducted to validate this claim have not been carried out...
  6. doi request reprint The deficit of pain inhibition in fibromyalgia is more pronounced in patients with comorbid depressive symptoms
    Juliana Barcellos de Souza
    Faculte de Medecine et des Sciences de la Sante, Universite de Sherbrooke, Sherbrooke, Canada
    Clin J Pain 25:123-7. 2009
    ..We hypothesized that the deficit in pain inhibition would be more pronounced in FM patients with depressive symptoms (FM+D), relative to patients without such symptoms (FM-D)...
  7. doi request reprint Fibromyalgia subgroups: profiling distinct subgroups using the Fibromyalgia Impact Questionnaire. A preliminary study
    Juliana Barcellos de Souza
    Faculte de Medecine et des Sciences de la Sante, Universite de Sherbrooke, Axe Douleur CRC CHUS, 3001, Sherbrooke, QC, Canada
    Rheumatol Int 29:509-15. 2009
    ..Both FM subgroups showed hyperalgesic responses to experimental pain. These results suggest that pain and stiffness are universal symptoms of the disorder but that psychological distress is a feature present only in some patients...
  8. doi request reprint Quality of life in neurooncology--age matters
    Nadia Veilleux
    Department of Neurosurgery and Neuro Oncology, Faculty of Medicine, Universite de Sherbrooke, Quebec, Canada
    J Neurosurg 113:325-32. 2010
    ..Unfortunately, an adult life-stage perspective has never been used to study the long-lasting impact of age on well-being in neurooncology patients...
  9. doi request reprint Pain perception in schizophrenia: evidence of a specific pain response profile
    Mylène Lévesque
    Departement de Neurochirurgie, Faculte de Medecine et des Sciences de la Sante, Universite de Sherbrooke, Sherbrooke, Canada
    Pain Med 13:1571-9. 2012
    ..The objective of this study was to characterize the pain response profile of schizophrenic patients by providing both acute and prolonged (i.e., rapidly repeating) painful stimuli to schizophrenic participants and control subjects...
  10. doi request reprint Evidence of descending inhibition deficits in atypical but not classical trigeminal neuralgia
    Guillaume Leonard
    Universite de Sherbrooke, Faculte de Medecine, Quebec, Canada
    Pain 147:217-23. 2009
    ..05). Taken together, these results suggest that the underlying physiopathology differs between CTN and ATN and that a deficit in descending inhibition may further contribute to the pain experienced by patients with ATN...
  11. doi request reprint Effects of surgical resection on the evolution of quality of life in newly diagnosed patients with glioblastoma: a report on 19 patients surviving to follow-up
    Kathya Daigle
    Universite de Sherbrooke, Faculty of Medicine, Department of Neurosurgery and Neuro Oncology, Sherbrooke, Quebec, Canada
    Curr Med Res Opin 29:1307-13. 2013
    ..The objective of the present study, therefore, was to study the relationship between tumor resection and QOL...
  12. doi request reprint An experimental model to measure excitatory and inhibitory pain mechanisms in humans
    Yannick Tousignant-Laflamme
    Centre de Recherche Clinique Etienne Le Bel, Universite de Sherbrooke, QC, Canada
    Brain Res 1230:73-9. 2008
    ..We were able to separate the effect of DNIC on the peak pain and on TS. This method is simple, sensitive and can easily be used in different population of either healthy subjects or chronic pain patients...
  13. doi request reprint Deciphering the role of endogenous opioids in high-frequency TENS using low and high doses of naloxone
    Guillaume Leonard
    Universite de Sherbrooke, Faculte de Medecine, Sherbrooke, Quebec, Canada J1H 5N4
    Pain 151:215-9. 2010
    ..An insufficient amount of opioid antagonist likely prevented previous human studies from discovering the importance of opioid receptors in producing high-frequency TENS analgesia...
  14. doi request reprint Comparing pain modulation and autonomic responses in fibromyalgia and irritable bowel syndrome patients
    Philippe Chalaye
    Department of Surgery, Universite de Sherbrooke, Sherbrooke, Quebec, Canada
    Clin J Pain 28:519-26. 2012
    ..The aim of the present study, therefore, was to compare descending pain inhibition, pain sensitivity, and ANS reactivity to pain in FM, IBS, and healthy controls (HC)...
  15. ncbi request reprint Changes in pain perception and descending inhibitory controls start at middle age in healthy adults
    Marianne Larivière
    Département des Sciences de la Santé, Université du Québec en Abitibi Témiscamingue, Rouyn Noranda, Quebec, Canada
    Clin J Pain 23:506-10. 2007
    ..The aims of the present study were to better characterize the developmental time course of the change in DNIC response by adding a middle-aged group. The role of expectations was also investigated...
  16. ncbi request reprint Analgesic and antihyperalgesic effects of nabilone on experimental heat pain
    William John Redmond
    Universite de Sherbrooke, Faculte de Medecine, Sherbrooke, Quebec, Canada
    Curr Med Res Opin 24:1017-24. 2008
    ..In this study, we explored the analgesic and antihyperalgesic properties of a synthetic cannabinoid (nabilone) on experimental heat pain in men and women, as well as its effects on descending pain inhibitory systems...
  17. doi request reprint Altered autonomic nervous system reactivity to pain in trigeminal neuralgia
    Guillaume Leonard
    1Centre de Recherche sur le Vieillissement, CSSS IUGS, Sherbrooke, Quebec, Canada
    Can J Neurol Sci 42:125-31. 2015
    ..The aim of the present study was to formally test this hypothesis by comparing the reactivity of the ANS to experimental pain in a population of TN patients and healthy controls...
  18. doi request reprint Sex differences in the neural representation of pain unpleasantness
    Lydia Girard-Tremblay
    School of Rehabilitation, Faculty of Medicine and Health Science, Universite de Sherbrooke, Sherbrooke, Quebec, Canada
    J Pain 15:867-77. 2014
    ....
  19. ncbi request reprint Does extent of resection impact survival in patients bearing glioblastoma?
    Nicolas Dea
    Surgery Department, Universite de Sherbrooke, Sherbrooke, Canada
    Can J Neurol Sci 39:632-7. 2012
    ..Amongst some of these uncontrolled factors, are the inclusion of different histological grades, the lack of objective methods to estimate the extent of resection and unspecified delays in post-operative imaging...
  20. doi request reprint Preterm births: can neonatal pain alter the development of endogenous gating systems?
    Philippe Goffaux
    Universite de Sherbrooke, Faculte de Medecine, Neurochirurgie, 3001, 12 e Avenue Nord, Sherbrooke, Quebec, Canada
    Eur J Pain 12:945-51. 2008
    ..Greater frequency of painful procedures also dampened the rise in heart rate normally observed when experimental pain is experienced...
  21. doi request reprint Triggering Descending Pain Inhibition by Observing Ourselves or a Loved-One in Pain
    Véronique Gougeon
    Departement de Chirurgie, Service de Neurochirurgie, Équipe de recherche sur la douleur École de réadaptation, Faculte de Medecine et des Sciences de la Sante, Universite de Sherbrooke, Sherbrooke Département de psychiatrie, Faculte de Medecine, Universite de Montreal, Montreal, QC, Canada
    Clin J Pain 32:238-45. 2016
    ..This study, therefore, aimed to determine if the observation of ourselves or a loved-one in pain could activate descending pain inhibition without exposure to a noxious stimulation; which is otherwise required...
  22. doi request reprint Significance of Non-phase Locked Oscillatory Brain Activity in Response to Noxious Stimuli
    Raphaël Dufort Rouleau
    1School of Rehabilitation, Universite de Sherbrooke, Sherbrooke, QC, Canada, J1H 5N4
    Can J Neurol Sci 42:436-43. 2015
    ..These types of activity bursts are known as induced brain responses. The significance of induced brain responses to pain is still unknown...
  23. doi request reprint The role of cardiovascular activity in fibromyalgia and conditioned pain modulation
    Philippe Chalaye
    Department of Surgery, Universite de Sherbrooke, Sherbrooke, Quebec, Canada
    Pain 155:1064-9. 2014
    ..Patients with FM have reduced blood pressure response to a painful CPT. Reduced cardiovascular reactivity to pain could have important involvement in diminished endogenous pain inhibition efficacy and FM pathophysiology. ..
  24. doi request reprint Randomized placebo-controlled cross-over designs in clinical trials: a gold standard to be reassessed
    Guillaume Leonard
    School of Rehabilitation, Universite de Sherbrooke, Faculty of Medicine, Sherbrooke, Quebec, Canada
    Curr Med Res Opin 28:245-8. 2012
    ..Frighteningly, this bias is always in the same direction, namely to increase the risk of rejecting potentially valid treatments. New models for clinical trials should be encouraged if we wish to market new and truly valid treatments...
  25. doi request reprint Relationship between blood- and cerebrospinal fluid-bound neurotransmitter concentrations and conditioned pain modulation in pain-free and chronic pain subjects
    Alexandre J Parent
    Department of Pharmacology and Physiology, Faculty of Medicine and Health Sciences, Universite de Sherbrooke, Sherbrooke, Quebec, Canada
    J Pain 16:436-44. 2015
    ....
  26. ncbi request reprint Descending analgesia--when the spine echoes what the brain expects
    Philippe Goffaux
    Universite de Sherbrooke, Faculte de Medecine, Sherbrooke, Que, Canada J1H 5N4
    Pain 130:137-43. 2007
    ....
  27. ncbi request reprint Development of a concise QOL questionnaire for brain tumor patients
    Philippe Goffaux
    Department of Neurosurgery and Neuro Oncology, Universite de Sherbrooke, Faculty of Medicine, Sherbrooke, Quebec, Canada
    Can J Neurol Sci 36:340-8. 2009
    ..The questionnaire departs from its predecessors in that it was designed for- and validated among French speaking Canadians...
  28. ncbi request reprint Neurophysiological measures of task-set switching: effects of working memory and aging
    Philippe Goffaux
    Department of Psychology, Centre for Research in Human Development, Concordia University, 7141 Sherbrooke Street West, Montreal, Quebec, Canada
    J Gerontol B Psychol Sci Soc Sci 63:P57-66. 2008
    ..High WM, therefore, may help older adults offset the age-related difficulties often observed when they are task switching...
  29. ncbi request reprint Cue- versus response-locked processes in backward inhibition: evidence from ERPs
    Marco Sinai
    Department of Psychology Centre for Research in Human Development, Concordia University, and Lady Davis Institute for Medical Research Jewish General Hospital, Montreal, Quebec, Canada
    Psychophysiology 44:596-609. 2007
    ....
  30. ncbi request reprint Different autonomic responses to experimental pain in IBS patients and healthy controls
    Yannick Tousignant-Laflamme
    Faculty of Medicine and Health Sciences, University of Sherbrooke, Sherbrooke, Quebec, Canada
    J Clin Gastroenterol 40:814-20. 2006
    ..Pain perception ratings in irritable bowel syndrome (IBS) patients suggest that they present either hypoalgesia or hyperalgesia. However, little is known about the physiologic responses these patients present to a somatic painful stimulus...