A Gupta

Summary

Affiliation: Division of Dermatology
Country: Canada

Publications

  1. ncbi In vitro activities of posaconazole, ravuconazole, terbinafine, itraconazole and fluconazole against dermatophyte, yeast and non-dermatophyte species
    A K Gupta
    Sunnybrook and Women s College Health Sciences Center, University of Toronto, Toronto, Canada
    Med Mycol 43:179-85. 2005
  2. doi The role of biofilms in onychomycosis
    Aditya K Gupta
    Department of Medicine, University of Toronto School of Medicine, Toronto, Ontario, Canada Mediprobe Research Inc, London, Ontario, Canada Electronic address
    J Am Acad Dermatol 74:1241-6. 2016
  3. ncbi Improving Cure Rates in Onychomycosis
    Aditya K Gupta
    Department of Medicine, University of Toronto, Toronto, ON, Canada
    J Cutan Med Surg 20:517-531. 2016
  4. ncbi Treating Alopecia Areata: Current Practices Versus New Directions
    Aditya K Gupta
    Department of Medicine, University of Toronto School of Medicine, Toronto, ON, Canada
    Am J Clin Dermatol . 2016
  5. doi The Rise and Fall of Oral Ketoconazole
    Aditya K Gupta
    Department of Medicine, University of Toronto, Toronto, Canada Mediprobe Research Inc, London, Ontario, Canada
    J Cutan Med Surg 19:352-7. 2015
  6. doi Progression of surgical hair restoration techniques
    Aditya K Gupta
    Department of Medicine, University of Toronto, Toronto, ON, and Mediprobe Research Inc, London, ON
    J Cutan Med Surg 19:17-21. 2015
  7. doi Management of Onychomycosis in Canada in 2014
    Aditya K Gupta
    Department of Medicine, University of Toronto, Toronto, ON, and Mediprobe Research Inc, London, ON
    J Cutan Med Surg 19:260-73. 2015
  8. doi Toenail Onychomycosis-A Canadian Approach With a New Transungual Treatment: Development of a Clinical Pathway
    Aditya K Gupta
    University of Toronto, Toronto, ON, Canada, and Mediprobe Research Inc, London, ON, Canada
    J Cutan Med Surg 19:440-9. 2015
  9. ncbi New antifungal agents
    Aditya K Gupta
    Division of Dermatology, Department of Medicine, Sunnybrook and Women s College Health Science Center Sunnybrook site, University of Toronto, 2075 Bayview Avenue, Toronto, Ontario M4N 3M5, Canada
    Dermatol Clin 21:565-76. 2003
  10. doi Interventions for actinic keratoses
    Aditya K Gupta
    Mediprobe Research Inc, London, Canada
    Cochrane Database Syst Rev 12:CD004415. 2012

Detail Information

Publications159 found, 100 shown here

  1. ncbi In vitro activities of posaconazole, ravuconazole, terbinafine, itraconazole and fluconazole against dermatophyte, yeast and non-dermatophyte species
    A K Gupta
    Sunnybrook and Women s College Health Sciences Center, University of Toronto, Toronto, Canada
    Med Mycol 43:179-85. 2005
    ....
  2. doi The role of biofilms in onychomycosis
    Aditya K Gupta
    Department of Medicine, University of Toronto School of Medicine, Toronto, Ontario, Canada Mediprobe Research Inc, London, Ontario, Canada Electronic address
    J Am Acad Dermatol 74:1241-6. 2016
    ..The biofilm is surprisingly resistant to injury and may act as a persistent source of infection possibly accounting for antifungal resistance in onychomycosis. ..
  3. ncbi Improving Cure Rates in Onychomycosis
    Aditya K Gupta
    Department of Medicine, University of Toronto, Toronto, ON, Canada
    J Cutan Med Surg 20:517-531. 2016
    ..Approximately 20% to 25% of patients with onychomycosis do not respond to treatment, and 10% to 53% of patients relapse. As such, successful treatment is imperative for long-term disease management...
  4. ncbi Treating Alopecia Areata: Current Practices Versus New Directions
    Aditya K Gupta
    Department of Medicine, University of Toronto School of Medicine, Toronto, ON, Canada
    Am J Clin Dermatol . 2016
    ..Preliminary data are encouraging, and it is hoped this research will translate into new options for the treatment of AA in the near future...
  5. doi The Rise and Fall of Oral Ketoconazole
    Aditya K Gupta
    Department of Medicine, University of Toronto, Toronto, Canada Mediprobe Research Inc, London, Ontario, Canada
    J Cutan Med Surg 19:352-7. 2015
    ..Growing evidence of serious side effects including endocrine dysregulation, several drug interactions, and death led to the review of oral ketoconazole in 2011...
  6. doi Progression of surgical hair restoration techniques
    Aditya K Gupta
    Department of Medicine, University of Toronto, Toronto, ON, and Mediprobe Research Inc, London, ON
    J Cutan Med Surg 19:17-21. 2015
    ..Early surgical hair restoration (SHR) techniques were fraught with limitations. Major advancements and refinements have taken place yielding minimally invasive, relatively scar-free, and natural-looking hair transplantations...
  7. doi Management of Onychomycosis in Canada in 2014
    Aditya K Gupta
    Department of Medicine, University of Toronto, Toronto, ON, and Mediprobe Research Inc, London, ON
    J Cutan Med Surg 19:260-73. 2015
    ..Onychomycosis has several clinical presentations and is caused by various infectious organisms...
  8. doi Toenail Onychomycosis-A Canadian Approach With a New Transungual Treatment: Development of a Clinical Pathway
    Aditya K Gupta
    University of Toronto, Toronto, ON, Canada, and Mediprobe Research Inc, London, ON, Canada
    J Cutan Med Surg 19:440-9. 2015
    ..The emergence of new topical drugs broadens the therapeutic options and prompts a re-evaluation of the current Canadian treatment strategy...
  9. ncbi New antifungal agents
    Aditya K Gupta
    Division of Dermatology, Department of Medicine, Sunnybrook and Women s College Health Science Center Sunnybrook site, University of Toronto, 2075 Bayview Avenue, Toronto, Ontario M4N 3M5, Canada
    Dermatol Clin 21:565-76. 2003
    ..The mechanisms of azole action and resistance themselves are not well understood, and further studies into azole susceptibility patterns are required...
  10. doi Interventions for actinic keratoses
    Aditya K Gupta
    Mediprobe Research Inc, London, Canada
    Cochrane Database Syst Rev 12:CD004415. 2012
    ..The interventions available for the treatment of actinic keratoses include individual lesion-based (e.g. cryotherapy) or field-directed (e.g. topical) treatments. These might vary in terms of efficacy, safety, and cosmetic outcomes...
  11. ncbi Recurrences of dermatophyte toenail onychomycosis during long-term follow-up after successful treatments with mono- and combined therapy of terbinafine and itraconazole
    Aditya K Gupta
    Department of Medicine, University of Toronto, Toronto, ON, Canada
    J Cutan Med Surg 17:201-6. 2013
    ..The influence of dosing regimens on the recurrence rates of onychomycosis has not been investigated...
  12. doi Diagnosing onychomycosis
    Aditya K Gupta
    Department of Medicine, University of Toronto School of Medicine, Toronto, Ontario, Canada Mediprobe Research, Inc, London, Ontario, Canada Electronic address
    Clin Dermatol 31:540-3. 2013
    ..Each of these tests has individual strengths in satisfying the three criteria, with a minimum of two positive diagnostic tests being the gold standard for confirming all three diagnostic criteria. ..
  13. ncbi Skin diseases associated with Malassezia species
    Aditya K Gupta
    Division of Dermatology, Department of Medicine, Sunnybrook and Women s College Health Science Center Sunnybrook site and the University of Toronto, Ontario, Canada
    J Am Acad Dermatol 51:785-98. 2004
    ..It also highlights the importance of individual Malassezia species in the different dermatologic disorders related to these yeasts...
  14. ncbi Nonpsoriatic uses of calcipotriol
    Aditya K Gupta
    Division of Dermatology, Department of Medicine, Sunnybrook and Women s College Health Sciences Center, Toronto, Ontario, Canada
    J Cutan Med Surg 6:442-8. 2002
    ..In vivo, calcipotriol has been shown to reduce the number of cycling epidermal cells. Calcipotriol also has less effect on calcium metabolism than calcitriol, which is the natural, bioactive, 1,25-dihydroxyvitamin D3...
  15. ncbi Comparison of efficacy criteria across onychomycosis trials: need for standardization
    Aditya K Gupta
    Division of Dermatology, Department of Medicine, Sunnybrook and Women s College Health Science Center Sunnybrook site, Toronto, Ontario, Canada
    Int J Dermatol 42:312-5. 2003
    ..The last 10 years have seen a substantial increase in the number of studies reporting the efficacy of the various antifungal agents used to treat onychomycosis...
  16. ncbi Itraconazole and terbinafine treatment of some nondermatophyte molds causing onychomycosis of the toes and a review of the literature
    A K Gupta
    Division of Dermatology, Department of Medicine, Sunnybrook and Women s College Health Science Center and the University of Toronto, Toronto, Canada
    J Cutan Med Surg 5:206-10. 2001
    ..Onychomycosis may be caused by dermatophytes (which form the majority of organisms), Candida species, and nondermatophyte molds...
  17. doi Medical devices for the treatment of onychomycosis
    Aditya K Gupta
    University of Toronto, Toronto, Ontario, Canada
    Dermatol Ther 25:574-81. 2012
    ..More studies are required to better determine their ability to treat onychomycosis...
  18. ncbi The use of terbinafine in the treatment of onychomycosis in adults and special populations: a review of the evidence
    Aditya K Gupta
    Division of Dermatology, Department of Medicine, Sunnybrook and Women s College Health Sciences Center Sunnybrook site, University of Toronto, Toronto, Canada
    J Drugs Dermatol 4:302-8. 2005
    ..Furthermore, the data support the use of terbinafine to treat dermatophyte onychomycosis in children and the elderly...
  19. doi Systemic antifungals to treat onychomycosis in children: a systematic review
    Aditya K Gupta
    Division of Dermatology, Department of Medicine, University of Toronto, Toronto, Canada Clinical Research, Mediprobe Research Inc, London, Ontario, Canada
    Pediatr Dermatol 30:294-302. 2013
    ..In conclusion, based on the little information available on onychomycosis in children, systemic antifungal therapies in children are safe and cure rates are similar to the rates achieved in adults...
  20. doi Drug safety assessment of oral formulations of ketoconazole
    Aditya K Gupta
    University of Toronto, Department of Medicine, Toronto, Ontario, Canada
    Expert Opin Drug Saf 14:325-34. 2015
    ..Post-marketing reports of drug-related hepatotoxicity, endocrine dysregulation and drug interactions resulted in market withdrawal of the drug in some countries and strict product relabeling in others...
  21. ncbi Itraconazole oral solution for the treatment of tinea capitis using the pulse regimen
    A K Gupta
    Department of Dermatology, Sunnybrook Health Science Center, Toronto, Ontario, Canada
    Cutis 64:192-4. 1999
    ..The availability of the oral solution will enable more young children to be considered for treatment of tinea capitis with itraconazole than was possible when only tablets or capsules were available...
  22. ncbi The use of sulfur in dermatology
    Aditya K Gupta
    Division of Dermatology, Department of Medicine, Sunnybrook and Women s College Health Science Center, University of Toronto, Toronto, Ontario, Canada
    J Drugs Dermatol 3:427-31. 2004
    ..Sulfur, used alone or in combination with agents such as sodium sulfacetamide or salicylic acid, has demonstrated efficacy in the treatment of many dermatological conditions...
  23. doi Update in antifungal therapy of dermatophytosis
    Aditya K Gupta
    Division of Dermatology, Department of Medicine, Sunnybrook Health Sciences Center, Toronto, ON, Canada
    Mycopathologia 166:353-67. 2008
    ..Relapse of infection remains a problem, particularly with tinea pedis/unguium. Appropriate follow-up duration and education of patients on proper foot hygiene are also important components in providing effective therapy...
  24. ncbi The diagnosis of nondermatophyte mold onychomycosis
    Aditya K Gupta
    Division of Dermatology, Department of Medicine, Sunnybrook and Women s College Health Science Center Sunnybrook site, Toronto, Ont, Canada
    Int J Dermatol 42:272-3. 2003
  25. ncbi The use of oral antifungal agents to treat onychomycosis
    Aditya K Gupta
    Division of Dermatology, Department of Medicine, Sunnybrook and Women s College Health Science Center Sunnybrook site, University of Toronto, 2075 Bayview Avenue, Toronto, Ontario M4N 3M5, Canada
    Dermatol Clin 21:469-79, vi. 2003
    ..This article reviews the oral antifungal agents used to treat onychomycosis...
  26. ncbi The use of fluconazole to treat superficial fungal infections in children
    Aditya K Gupta
    Division of Dermatology, Department of Medicine, Sunnybrook and Women s College Health Science Center Sunnybrook site, University of Toronto, 2075 Bayview Avenue, Toronto, Ontario M4N 3M5, Canada
    Dermatol Clin 21:537-42. 2003
    ..Further studies need to be conducted, particularly in cases of tinea capitis (both T. tonsurans and M. canis), to determine the optimal treatment regimens using fluconazole...
  27. doi New pharmacotherapy for the treatment of onychomycosis: an update
    Aditya K Gupta
    Mediprobe Research, Inc, 645 Windermere Rd, London, ON, N5X 2P1, Canada 1 519 851 9715 1 519 657 4233
    Expert Opin Pharmacother 16:227-36. 2015
    ..The current gold standard is oral therapy, but the development of effective topical agents remains a priority as they have fewer systemic interactions...
  28. ncbi Onychomycosis associated with Onychocola canadensis: ten case reports and a review of the literature
    A K Gupta
    Department of Medicine, Sunnybrook Health Science Center and the University of Toronto, Ontario, Canada
    J Am Acad Dermatol 39:410-7. 1998
    ..The slow growth rate of O canadensis and lack of resemblance to any other known nail-infecting fungus may have delayed its discovery. We are aware of 23 mycologically confirmed cases of O canadensis in the literature...
  29. ncbi Itraconazole oral solution for the treatment of tinea capitis
    A K Gupta
    Department of Medicine, Sunnybrook Health Science Center, Toronto, Ontario, Canada
    Br J Dermatol 139:104-6. 1998
    ..It remains to be seen whether itraconazole oral solution will become a practical alternative to the antifungal agents available in a liquid preparation for the treatment of tinea capitis...
  30. ncbi Update on the safety of itraconazole pulse therapy in onychomycosis and dermatomycoses
    A Gupta
    Department of Medicine, University of Toronto, Toronto, Canada
    Eur J Dermatol 11:6-10. 2001
    ..Adverse events are generally mild and transient. Furthermore, a dose increase to 400 mg in the pulse regimen has had no adverse impact on safety...
  31. ncbi Single-blind, randomized, prospective study on terbinafine and itraconazole for treatment of dermatophyte toenail onychomycosis in the elderly
    A K Gupta
    Department of Medicine, Sunnybrook and Women s College Health Sciences Center, Toronto, Ontario, Canada
    J Am Acad Dermatol 44:479-84. 2001
    ..Although comparative studies have been performed evaluating the efficacy of these 2 agents in adults, no such studies have been reported specifically in the elderly subset...
  32. ncbi The epidemiology of onychomycosis: possible role of smoking and peripheral arterial disease
    A K Gupta
    Department of Medicine, Sunnybrook and Women s College Health Sciences Center, and University of Toronto, Canada
    J Eur Acad Dermatol Venereol 14:466-9. 2000
    ..In our clinical practice we have observed that smokers and individuals with peripheral arterial disease may have an increased prevalence of onychomycosis compared to normal individuals...
  33. ncbi Quantitative culture of Malassezia species from different body sites of individuals with or without dermatoses
    A K Gupta
    Department of Medicine, Women s College Hospital, University of Toronto, Canada
    Med Mycol 39:243-51. 2001
    ..Among normal individuals and for patients with AD and PV, M. sympodialis was significantly more likely to affect the forehead than the legs...
  34. ncbi Critical review of the manner in which the efficacy of therapies for rosacea are evaluated
    Aditya K Gupta
    Division of Dermatology, Department of Medicine, Sunnybrook and Women s College Health Science Center Sunnybrook site, The University of Toronto, Ontario, Canada
    Int J Dermatol 42:909-16. 2003
    ..Many agents have been used to treat rosacea stigmata, especially because none of these is uniformly effective...
  35. ncbi Role of antifungal agents in the treatment of seborrheic dermatitis
    Aditya K Gupta
    Division of Dermatology, Department of Medicine, Sunnybrook and Women s College Health Science Center Sunnybrook site and the University of Toronto, Toronto, Ontario, Canada
    Am J Clin Dermatol 5:417-22. 2004
    ..With a wide availability of preparations, including creams, shampoos, and oral formulations, antifungal agents are safe and effective in the treatment of seborrheic dermatitis...
  36. doi The use of an intermittent terbinafine regimen for the treatment of dermatophyte toenail onychomycosis
    A K Gupta
    Division of Dermatology, Department of Medicine, Sunnybrook Health Sciences Center and the University of Toronto, Toronto, Ontario, Canada
    J Eur Acad Dermatol Venereol 23:256-62. 2009
    ..To compare the efficacy and safety of intermittent terbinafine with standard courses of terbinafine and itraconazole for dermatophyte toenail onychomycosis...
  37. doi Network meta-analysis of the outcome 'participant complete clearance' in nonimmunosuppressed participants of eight interventions for actinic keratosis: a follow-up on a Cochrane review
    A K Gupta
    Department of Medicine, University of Toronto, Toronto, ON, Canada
    Br J Dermatol 169:250-9. 2013
    ..However, several other factors should also be considered when prescribing a treatment for AK...
  38. doi Topical therapy for toenail onychomycosis: an evidence-based review
    Aditya K Gupta
    University of Toronto, Toronto, Canada
    Am J Clin Dermatol 15:489-502. 2014
    ..However, oral medications may not be suitable for some patients, because of drug interactions; therefore, topical treatments are critical in managing the disease in certain patient populations...
  39. ncbi Onychomycosis: strategies to reduce failure and recurrence
    A K Gupta
    Department of Medicine, Sunnybrook Health Science Center, Ontario, Canada
    Cutis 62:189-91. 1998
    ..We review here some instances in which this is appropriate, as well as strategies to reduce recurrence of onychomycosis...
  40. ncbi Therapeutic options for the treatment of tinea capitis caused by Trichophyton species: griseofulvin versus the new oral antifungal agents, terbinafine, itraconazole, and fluconazole
    A K Gupta
    Division of Dermatology, Department of Medicine, Sunnybrook and Women s College Health Sciences Center Sunnybrook site, Toronto, Canada
    Pediatr Dermatol 18:433-8. 2001
    ..Each of the agents has a favorable adverse-effects profile...
  41. ncbi Prevalence and epidemiology of toenail onychomycosis in diabetic subjects: a multicentre survey
    A K Gupta
    Division of Dermatology, Department of Medicine, Sunnybrook Health Science Center and the University of Toronto, Toronto, Canada
    Br J Dermatol 139:665-71. 1998
    ..Predisposing factors include increasing age, male gender, family history of onychomycosis, concurrent intake of immunosuppressive agents and peripheral vascular disease...
  42. ncbi Prescribing practices for seborrheic dermatitis vary with the physician's specialty: implications for clinical practice
    A K Gupta
    Division of Dermatology, Department of Medicine, Sunnybrook and Women s College Health Science Center, Sunnybrook Site, University of Toronto, Canada
    J Dermatolog Treat 15:208-13. 2004
    ....
  43. ncbi Ingenol mebutate: a promising treatment for actinic keratoses and nonmelanoma skin cancers
    Aditya K Gupta
    Department of Medicine, University of Toronto, Toronto, ON, Canada
    J Cutan Med Surg 17:173-9. 2013
    ..A new treatment for actinic keratoses, ingenol mebutate, was recently approved by the US Food and Drug Administration...
  44. ncbi Pharmacoeconomic analysis of oral antifungal therapies used to treat dermatophyte onychomycosis of the toenails. A US analysis
    A K Gupta
    Department of Medicine, Sunnybrook Health Science Center, Toronto, Ontario, Canada
    Pharmacoeconomics 13:243-56. 1998
    ..62. In conclusion, in this analysis, itraconazole (pulse) and terbinafine were the most cost-effective therapies for dermatophyte onychomycosis of the toenails, both being substantially more cost effective than griseofulvin...
  45. ncbi A risk-benefit assessment of the newer oral antifungal agents used to treat onychomycosis
    A K Gupta
    Department of Medicine, Sunnybrook and Women s Health Sciences Center, University of Toronto Medical School, Canada
    Drug Saf 22:33-52. 2000
    ..The newer antifungal agents are generally well tolerated with drug interactions that are usually predictable...
  46. ncbi In vitro susceptibility of the seven Malassezia species to ketoconazole, voriconazole, itraconazole and terbinafine
    A K Gupta
    Division of Dermatology, Department of Medicine, Sunnybrook and Women s College Health Sciences Center Sunnybrook site and the University of Toronto, Canada
    Br J Dermatol 142:758-65. 2000
    ..M. furfur strains tested with terbinafine ranged from highly susceptible to relatively resistant. Correct identification of Malassezia species could facilitate selection of appropriate antifungal therapy...
  47. ncbi Onychomycosis in the elderly
    A K Gupta
    Department of Medicine, Sunnybrook and Women s College Health Sciences Center, University of Toronto, Ontario, Canada
    Drugs Aging 16:397-407. 2000
    ..Once cure has been achieved, it is important to counsel patients on the strategies of reducing recurrence of disease...
  48. ncbi Detection of xanthomegnin in epidermal materials infected with Trichophyton rubrum
    A K Gupta
    Division of Dermatology, Department of Medicine, Sunnybrook and Women s College Health Sciences Center Sunnybrook site, and the University of Toronto, Toronto, Ontario, Canada
    J Invest Dermatol 115:901-5. 2000
    ..Xanthomegnin was not detected in uninfected nails. These results show that patients with Trichophyton rubrum infections may be exposed to xanthomegnin, although the consequences of such an exposure are not currently known...
  49. ncbi Epidemiology of Malassezia yeasts associated with pityriasis versicolor in Ontario, Canada
    A K Gupta
    Department of Medicine, Sunnybrook and Women s College Health Sciences Center, University of Toronto, Ontario, Canada
    Med Mycol 39:199-206. 2001
    ....
  50. ncbi A randomized, double-blind, multicenter, parallel group study to compare relative efficacies of the topical gels 3% erythromycin/5% benzoyl peroxide and 0.025% tretinoin/erythromycin 4% in the treatment of moderate acne vulgaris of the face
    Aditya K Gupta
    Division of Dermatology, Department of Medicine, Sunnybrook and Women s College Health Science Center and the University of Toronto, Toronto, Ontario, Canada
    J Cutan Med Surg 7:31-7. 2003
    ..A combination preparation containing the two antibiotics may reduce the development of resistance; the combination preparation containing tretinoin and erythromycin will have an antibiotic effect as well as acting on differentiation...
  51. ncbi Non-dermatophyte onychomycosis
    Aditya K Gupta
    Division of Dermatology, Department of Medicine, Sunnybrook and Women s College Health Science Center Sunnybrook site, Toronto, Canada
    Dermatol Clin 21:257-68. 2003
    ..While many patients with non-dermatophyte mold onychomycosis will respond to oral or topical antifungal therapy, poor or incomplete response might still be expected in some patients...
  52. ncbi Pimecrolimus: a review
    A K Gupta
    Division of Dermatology, Department of Medicine, Sunnybrook and Women s College Health Science Center Sunnybrook site and the University of Toronto, Toronto, Canada
    J Eur Acad Dermatol Venereol 17:493-503. 2003
    ..It has been shown to be effective in atopic and allergic contact dermatitis, with a favorable adverse-effects profile, which includes little effect on the systemic immune response...
  53. ncbi The use of topical therapies to treat onychomycosis
    Aditya K Gupta
    Division of Dermatology, Department of Medicine, Sunnybrook and Women s College Health Science Center Sunnybrook site, University of Toronto, 2075 Bayview Avenue, Toronto, Ontario M4N 3M5, Canada
    Dermatol Clin 21:481-9. 2003
    ..Topical agents have a favorable adverse events profile. Further studies are required on the treatment of onychomycosis with nail lacquers...
  54. ncbi How to improve cure rates for the management of onychomycosis
    Aditya K Gupta
    Division of Dermatology, Department of Medicine, Sunnybrook and Women s College Health Science Center Sunnybrook site, University of Toronto, 2075 Bayview Avenue, Toronto, Ontario M4N 3M5, Canada
    Dermatol Clin 21:499-505, vii. 2003
    ..Familiarity with the symptoms and signs of tinea pedis and onychomycosis may enable patients to seek appropriate care when the disease is at an early stage...
  55. ncbi The efficacy and safety of terbinafine in children
    Aditya K Gupta
    Division of Dermatology, Department of Medicine, Sunnybrook and Women s College Health Science Center Sunnybrook site, University of Toronto, 2075 Bayview Avenue, Toronto, Ontario M4N 3M5, Canada
    Dermatol Clin 21:511-20. 2003
    ..The evidence is strongly in favor of using terbinafine to treat superficial fungal infections in children...
  56. ncbi Superficial fungal infections: an update on pityriasis versicolor, seborrheic dermatitis, tinea capitis, and onychomycosis
    Aditya K Gupta
    Division of Dermatology, Department of Medicine, Sunnybrook and Women s College Health Science Center Sunnybrook site and the University of Toronto, Toronto, Ontario, Canada
    Clin Dermatol 21:417-25. 2003
    ..The use of combination therapies in some circumstances to maximize cure rates is reviewed...
  57. ncbi Seborrheic dermatitis of the scalp: etiology and treatment
    Aditya K Gupta
    Division of Dermatology, Department of Medicine, Sunnybrook and Women s College Health Science Center Sunnybrook site and the University of Toronto, Toronto, Canada
    J Drugs Dermatol 3:155-8. 2004
    ..This paper will discuss the role of Malassezia in the etiology of seborrheic dermatitis, as well as the various treatment options...
  58. ncbi Prednicarbate (dermatop): a review
    Aditya K Gupta
    Department of Medicine, Sunnybrook and Women s College Health Science Center Sunnybrook site and the University of Toronto, Toronto, Canada
    J Drugs Dermatol 3:553-6. 2004
    ..Prednicarbate may be particularly advantageous when used intermittently in pediatric and elderly patients...
  59. ncbi Treatment of onychomycosis: pros and cons of antifungal agents
    Aditya K Gupta
    Division of Dermatology, Department of Medicine, Sunnybrook and Women s College Health Science Center Sunnybrook site and the University of Toronto, Toronto, Ontario, Canada
    J Cutan Med Surg 8:25-30. 2004
    ..In addition, there is limited information about the use of antifungal agents in special populations, e.g., children...
  60. ncbi Ciclopirox 1% shampoo for the treatment of seborrheic dermatitis
    Aditya K Gupta
    Division of Dermatology, Department of Medicine, Sunnybrook and Women s College Health Science Center Sunnybrook site and the University of Toronto, Canada
    Int J Dermatol 45:66-9. 2006
    ..Varying frequencies and concentrations of ciclopirox shampoo have been shown to be effective and safe in the treatment of seborrheic dermatitis of the scalp...
  61. doi New therapeutic options for onychomycosis
    Aditya K Gupta
    Division of Dermatology, Department of Medicine, University of Toronto, Toronto, Ontario, Canada
    Expert Opin Pharmacother 13:1131-42. 2012
    ..New therapeutic options are needed to broaden the spectrum of treatment options and improve the efficacy of treatment...
  62. doi Therapies for the treatment of onychomycosis
    Aditya K Gupta
    Department of Medicine, University of Toronto School of Medicine, Toronto, Ontario, Canada Mediprobe Research, Inc, London, Ontario, Canada Electronic address
    Clin Dermatol 31:544-54. 2013
    ....
  63. doi Investigational drugs for onychomycosis
    Aditya K Gupta
    Department of Medicine, University of Toronto, Toronto, Ontario, Canada 1 519 657 4222 ext 277 1 519 657 4233
    Expert Opin Investig Drugs 23:97-106. 2014
    ..Oral therapy is limited by adverse events and drug-drug interactions, whereas topical therapy has limited penetrance through the nail plate...
  64. doi Improved efficacy in onychomycosis therapy
    Aditya K Gupta
    Department of Medicine, University of Toronto School of Medicine, Toronto, Ontario, Canada Mediprobe Research, Inc, London, Ontario, Canada Electronic address
    Clin Dermatol 31:555-63. 2013
    ..An improved efficacy was demonstrated for some of these strategies, such as combined oral and topical antifungal therapies, whereas most of them lack clear and direct evidence of an increase in therapeutic success. ..
  65. doi Evidence-based optimal fluconazole dosing regimen for onychomycosis treatment
    Aditya K Gupta
    Department of Medicine, Division of Dermatology, University of Toronto, Toronto, Canada
    J Dermatolog Treat 24:75-80. 2013
    ..By restricting the data to dermatophyte onychomycosis, we aimed to identify an optimal fluconazole dosing regimen...
  66. doi Meta-analysis of randomized, controlled trials comparing particular doses of griseofulvin and terbinafine for the treatment of tinea capitis
    Aditya K Gupta
    University of Toronto, Toronto, Ontario, Canada
    Pediatr Dermatol 30:1-6. 2013
    ..infection (p = 0.04). Our results support species-specific differences in treatment efficacy between griseofulvin and terbinafine and provide a clinical context in which this knowledge may be applied...
  67. ncbi Newly approved laser systems for onychomycosis
    Aditya K Gupta
    Division of Dermatology, Department of Medicine, University of Toronto, Toronto, Canada
    J Am Podiatr Med Assoc 102:428-30. 2012
    ....
  68. ncbi The use of itraconazole to treat cutaneous fungal infections in children
    A K Gupta
    Division of Dermatology, Department of Medicine, Sunnybrook and Women s College Health Sciences Center Sunnybrook site, and the University of Toronto, Toronto, Canada
    Dermatology 199:248-52. 1999
    ..There is relatively limited data regarding the use of the newer oral antifungal agents, e.g. itraconazole, in the treatment of these mycoses in children...
  69. ncbi Open-label study to evaluate the healing rate and safety of the Profore Extra Four-Layer Bandage System in patients with venous leg ulceration
    A K Gupta
    Division of Dermatology, Department of Medicine, Sunnybrook and Womens Health Sciences Centre Sunnybrook Site and the University of Toronto Medical School, Toronto, Ontario, Canada
    J Cutan Med Surg 4:8-11. 2000
    ..Venous ulcers are increasing in prevalence, especially since these are observed more frequently in the elderly, and the number of individuals in this age group is becoming a larger portion of the population...
  70. pmc Molecular differentiation of seven Malassezia species
    A K Gupta
    Division of Dermatology, Department of Medicine, Sunnybrook Health Science Center and University of Toronto, Toronto, Ontario, Canada
    J Clin Microbiol 38:1869-75. 2000
    ..pachydermatis. This specific amplification may facilitate the rapid identification of this organism...
  71. ncbi Hepatic safety of itraconazole
    Aditya K Gupta
    University of Toronto, Toronto, Canada
    J Cutan Med Surg 6:210-3. 2002
    ..The most common adverse events are gastrointestinal upset, headache, and transient skin reaction. There have also been rare reports of hepatitis...
  72. ncbi Fungicidal activities of commonly used disinfectants and antifungal pharmaceutical spray preparations against clinical strains of Aspergillus and Candida species
    A K Gupta
    Department of Medicine, Sunnybrook and Women s College Health Sciences Center, Toronto, Ontario, Canada
    Med Mycol 40:201-8. 2002
    ..ochraceus conidia and an onset of fungicidal effect on C. parapsilosis yeast cells. Terbinafine was only moderately effective against C. albicans and was completely ineffective against C. krusei...
  73. ncbi Onychomycosis: quality of studies
    Aditya K Gupta
    Division of Dermatology, Department of Medicine, Sunnybrook and Women s College Health Science Center Sunnybrook site and the University of Toronto, Toronto, Canada
    J Cutan Med Surg 7:312-6. 2003
    ..The quality of original clinical trial publications pertaining to the use of oral antifungal agents to treat onychomycosis was evaluated using predetermined criteria...
  74. ncbi Interdigital tinea pedis (dermatophytosis simplex and complex) and treatment with ciclopirox 0.77% gel
    Aditya K Gupta
    Division of Dermatology, Department of Medicine, Sunnybrook and Women s College Health Sciences Center Sunnybrook site and the University of Toronto, Toronto, Canada
    Int J Dermatol 42:23-7. 2003
    ....
  75. ncbi Evaluating the quality of rosacea studies: implications for the patient and physician
    Aditya K Gupta
    Division of Dermatology, Department of Medicine, Sunnybrook and Women s College Health Science Center Sunnybrook site and the University of Toronto, Toronto, Ont, Canada
    Dermatology 207:173-7. 2003
    ..Patients suffering from rosacea may experience frequent blushing and flushing, erythema, telangiectasia, and/or rhinophyma. In an attempt to find effective treatments, many studies have been performed...
  76. ncbi Analysis of factors associated with increased prescription illegibility: results from the National Ambulatory Medical Care Survey, 1990-1998
    Aditya K Gupta
    Division of Dermatology, Department of Medicine, Sunnybrook and Women s College Health Sciences Centre Sunnybrook campus, Toronto, Ontario, Canada
    Am J Manag Care 9:548-52. 2003
    ..To estimate the incidence of, and the variables affecting, illegible drug prescriptions in the United States...
  77. ncbi Efficacy and safety of itraconazole use in children
    Aditya K Gupta
    Division of Dermatology, Department of Medicine, Sunnybrook and Women s College Health Science Center Sunnybrook site, University of Toronto, 2075 Bayview Avenue, Toronto, Ontario M4N 3M5, Canada
    Dermatol Clin 21:521-35. 2003
    ....
  78. ncbi Evaluation of in vitro resistance in patients with onychomycosis who fail antifungal therapy
    Aditya K Gupta
    Division of Dermatology, Department of Medicine, Sunnybrook and Women s College Health Science Center, Sunnybrook site and the University of Toronto, Toronto, Ontario, Canada
    Dermatology 207:375-80. 2003
    ..However, relatively little research has been published concerning the resistance of dermatophyte species...
  79. ncbi The efficacy and safety of terbinafine in children
    A K Gupta
    Division of Dermatology, Department of Medicine, Sunnybrook and Women s College Health Sciences Center Sunnybrook site and the University of Toronto, Toronto, Canada
    J Eur Acad Dermatol Venereol 17:627-40. 2003
    ..The adverse events profile for children is similar to that in adults with few adverse effects associated with its use. The evidence favours the use of terbinafine in the treatment of superficial infections in children...
  80. ncbi Prevalence of Malassezia species on various body sites in clinically healthy subjects representing different age groups
    Aditya K Gupta
    Division of Dermatology, Department of Medicine, Sunnybrook and Women s College Health Science Center Sunnybrook site, University of Toronto, Toronto, Ontario, Canada
    Med Mycol 42:35-42. 2004
    ..The amount and kind of Malassezia species that can be recovered from human skin varies with age and body site...
  81. ncbi Cumulative meta-analysis of systemic antifungal agents for the treatment of onychomycosis
    A K Gupta
    Division of Dermatology, Department of Medicine, Sunnybrook and Women s College Health Science Center Sunnybrook site and the University of Toronto, Toronto, Ontario, Canada
    Br J Dermatol 150:537-44. 2004
    ..Onychomycosis is a common nail disease that is often chronic, difficult to eradicate, and has a tendency to recur. The most common oral therapies for dermatophyte toenail onychomycosis include terbinafine, itraconazole and fluconazole...
  82. ncbi Management of diaper dermatitis
    Aditya K Gupta
    Division of Dermatology, Department of Medicine, Sunnybrook and Women s College Health Sciences Center Sunnybrook site, London, Ontario, Canada
    Int J Dermatol 43:830-4. 2004
  83. ncbi A review of the use of infliximab to manage cutaneous dermatoses
    Aditya K Gupta
    Division of Dermatology, Department of Medicine, Sunnybrook and Women s College Health Sciences Center Sunnybrook site and the University of Toronto, Toronto, Canada
    J Cutan Med Surg 8:77-89. 2004
    ..Infliximab is a chimeric monoclonal antibody that binds specifically to human tumor necrosis factor-alpha (TNF-alpha), decreasing the effect of the cytokine in inflammatory diseases...
  84. ncbi Viral and nonviral uses of imiquimod: a review
    Aditya K Gupta
    Division of Dermatology, Department of Medicine, Sunnybrook and Women s College Health Science Center, University of Toronto, Toronto, Ontario, Canada
    J Cutan Med Surg 8:338-52. 2004
    ..This drug has been recently approved for the treatment of actinic keratoses and superficial basal cell carcinoma. There is a growing body of evidence for its effectiveness in treating a variety of other skin conditions...
  85. ncbi Evaluation of the efficacy of ciclopirox 0.77% gel in the treatment of tinea pedis interdigitalis (dermatophytosis complex) in a randomized, double-blind, placebo-controlled trial
    Aditya K Gupta
    Division of Dermatology, Department of Medicine, Sunnybrook and Women s College Health Sciences Center, Toronto, Canada
    Int J Dermatol 44:590-3. 2005
    ..These properties may give ciclopirox an advantage over other antifungal agents in the treatment of interdigital tinea pedis with secondary bacterial infection (dermatophytosis complex)...
  86. ncbi Therapies for onychomycosis: a review
    Aditya K Gupta
    Division of Dermatology, Department of Medicine, Sunnybrook and Women s College Health Sciences Centre, Sunnybrook Site, University of Toronto, 2075 Bayview Avenue Toronto, ON M4N 3M5, Canada
    Dermatol Clin 24:375-9. 2006
    ..Surgical, chemical, topical, and oral methods are reviewed in this article, with an emphasis on the three systemic treatments approved by the US Food and Drug Administration: terbinafine, itraconazole, and griseofulvin...
  87. ncbi Meta-analysis: griseofulvin efficacy in the treatment of tinea capitis
    Aditya K Gupta
    Division of Dermatology, Department of Medicine, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, ON, Canada
    J Drugs Dermatol 7:369-72. 2008
    ..Both genera showed good efficacy with griseofulvin therapy given from 6 to 8 weeks. Griseofulvin remains an effective therapy for tinea capitis...
  88. doi Systematic review of nondermatophyte mold onychomycosis: diagnosis, clinical types, epidemiology, and treatment
    Aditya K Gupta
    University of Toronto, Toronto, Ontario, Canada
    J Am Acad Dermatol 66:494-502. 2012
    ..When evaluating different treatments, we suggest that authors clearly define their efficacy outcomes...
  89. ncbi An overview of topical antifungal therapy in dermatomycoses. A North American perspective
    A K Gupta
    Department of Medicine, Sunnybrook Health Science Center, Toronto, Ontario, Canada
    Drugs 55:645-74. 1998
    ..For tinea pedis the most common treatment duration is 4 to 6 weeks...
  90. ncbi A questionnaire study on the management of onychomycosis: a Canadian perspective
    A K Gupta
    Department of Medicine, Sunnybrook Health Science Center, Toronto, Canada
    Int J Dermatol 37:457-60. 1998
    ..Onychomycosis of the toenails is a condition that responds poorly to griseofulvin. The introduction of terbinafine in Canada in May 1993 resulted in a marked shift in the choice of treatment for pedal onychomycosis...
  91. ncbi Increased incidence of Trichophyton tonsurans tinea capitis in Ontario, Canada between 1985 and 1996
    A K Gupta
    Division of Dermatology, Department of Medicine, Sunnybrook Health Science Center and the University of Toronto, Toronto, Ontario, Canada
    Med Mycol 36:55-60. 1998
    ..This should provide guidance regarding where to concentrate health resources and deliver patient/parent education to combat this epidemic of tinea capitis...
  92. ncbi Factors that may affect the response of onychomycosis to oral antifungal therapy
    A K Gupta
    Department of Medicine, Sunnybrook Health Science Center, Toronto, Canada
    Australas J Dermatol 39:222-4. 1998
    ..Possible explanations for this may be grouped into categories, including: (i) patient characteristics; (ii) organisms causing or associated with the nail infection; (iii) nail characteristics; and (iv) local diseases involving the nail...
  93. ncbi Itraconazole pulse therapy is effective in the treatment of Majocchi's granuloma: a clinical and pharmacokinetic evaluation and implications for possible effectiveness in tinea capitis
    A K Gupta
    Department of Dermatology, Sunnybrook Health Science Center, Toronto, Ontario, Canada
    Clin Exp Dermatol 23:103-8. 1998
    ..These data suggest that itraconazole pulse therapy should be effective in the treatment of tinea capitis...
  94. ncbi Onychomycosis in children: prevalence and management
    A K Gupta
    Sunnybrook Health Science Center, Division of Dermatology, University of Toronto, Ontario, Canada
    Pediatr Dermatol 15:464-71. 1998
    ..The data suggest that the new oral antifungal agents have a role in the treatment of onychomycosis in children. Further experience will help us better position these drugs when evaluating the management of onychomycosis in children...
  95. ncbi Itraconazole oral solution for the treatment of onychomycosis
    A K Gupta
    Sunnybrook Health Science Center, Division of Dermatology, University of Toronto, Ontario, Canada
    Pediatr Dermatol 15:472-4. 1998
    ..Both patients were clinically and mycologically cured with no adverse effects. Itraconazole oral solution (3 mg/kg/day) given as pulse therapy may be a consideration in the treatment of onychomycosis in some children...
  96. ncbi Tinea capitis: an overview with emphasis on management
    A K Gupta
    Division of Dermatology, Department of Medicine, Sunnybrook Health Science Center, Toronto, Ontario, Canada University of Toronto, Toronto, Ontario, Canada
    Pediatr Dermatol 16:171-89. 1999
    ..Adjunctive therapies may help decrease the risk of infection to other individuals. Appropriate measures should be taken to reduce the possibility of reinfection...
  97. ncbi Drug interactions with itraconazole, fluconazole, and terbinafine and their management
    A K Gupta
    Division of Dermatology, Department of Medicine, University of Toronto, London, Ontario, N6K 1L6, Canada
    J Am Acad Dermatol 41:237-49. 1999
    ..In the case of contraindicated drugs, it may be possible to use an alternative agent...
  98. ncbi Intermittent short duration therapy with fluconazole is effective for tinea capitis
    A K Gupta
    Department of Medicine, Sunnybrook and Women s College Health Sciences Center Sunnybrook site and the University of Toronto, Toronto N6K 1L6, Canada
    Br J Dermatol 141:304-6. 1999
    ..This regimen appears to be effective and safe, and is associated with high compliance. The preliminary results of the investigation need to be evaluated in a larger sample of patients, and in tinea capitis caused by zoophilic species...
  99. ncbi Management of onychomycosis in children
    A K Gupta
    Division of Dermatology, University of Toronto Faculty of Medicine, Ontario, Canada
    Postgrad Med . 1999
    ..Terbinafine (continuous) or fluconazole (intermittent) regimens are other treatment options. It is important to take steps to reduce the risk of reinfection and to treat tinea pedis at an early stage...
  100. ncbi The new oral antifungal agents for onychomycosis of the toenails
    A K Gupta
    Department of Medicine, Sunnybrook Health Science Center and the University of Toronto, Canada
    J Eur Acad Dermatol Venereol 13:1-13. 1999
    ..To review the use of the new oral antifungal agents, itraconazole, terbinafine and fluconazole for the treatment of onychomycosis of the toenails...
  101. ncbi Combined distal and lateral subungual and white superficial onychomycosis in the toenails
    A K Gupta
    Department of Medicine, Sunnybrook Health Sciences Center and the University of Toronto, and the Ontario Ministry of Health, Laboratory Services Branch and Department of Laboratory Medicine and Pathology, University of Toronto
    J Am Acad Dermatol 41:938-44. 1999
    ..In the literature there is infrequent discussion about 2 types of onychomycosis present in the toenails of the same individual...