Sander Veldhuyzen van Zanten

Summary

Affiliation: Dalhousie University
Country: Canada

Publications

  1. pmc The influence of demographic factors and health-related quality of life on treatment satisfaction in patients with gastroesophageal reflux disease treated with esomeprazole
    Alessio Degl' Innocenti
    AstraZeneca R and D, 431 83 Mölndal, Sweden
    Health Qual Life Outcomes 3:4. 2005
  2. pmc The impact of illness in patients with moderate to severe gastro-esophageal reflux disease
    Samer El-Dika
    Division of Gastroenterology, Veterans Affairs Medical Center, Salem, Virginia, USA
    BMC Gastroenterol 5:23. 2005
  3. ncbi request reprint One-week triple therapy with esomeprazole, clarithromycin and metronidazole provides effective eradication of Helicobacter pylori infection
    S Veldhuyzen Van Zanten
    Division of Gastroenterology, Department of Medicine, Dalhousie University, Halifax, Canada
    Aliment Pharmacol Ther 17:1381-7. 2003
  4. ncbi request reprint The prevalence of Barrett's oesophagus in a cohort of 1040 Canadian primary care patients with uninvestigated dyspepsia undergoing prompt endoscopy
    S J O Veldhuyzen van Zanten
    Division of Gastroenterology, Dalhousie University, Halifax, NS, Canada
    Aliment Pharmacol Ther 23:595-9. 2006
  5. ncbi request reprint Upper gastrointestinal alarms: the 2-week rule
    Sander Veldhuyzen van Zanten
    Queen Elizabeth II Health Sciences Center, Victoria General Hospital Site, Halifax, Nova Scotia, B3H 2Y9, Canada
    Lancet 365:2163-4. 2005
  6. ncbi request reprint Review article: the changing epidemiology of hepatocellular carcinoma in Canada
    Z Dyer
    Department of Medicine, Queen Elizabeth II Health Sciences Center, Dalhousie University, Halifax, NS, Canada
    Aliment Pharmacol Ther 22:17-22. 2005
  7. ncbi request reprint Systematic review: the efficacy of intermittent and on-demand therapy with histamine H2-receptor antagonists or proton pump inhibitors for gastro-oesophageal reflux disease patients
    J Zacny
    Division of Gastroenterology, Queen Elizabeth II Health Sciences Centre, Halifax, Nova Scotia, Canada
    Aliment Pharmacol Ther 21:1299-312. 2005
  8. ncbi request reprint Cost-effectiveness of intravenous proton pump inhibitors in high-risk bleeders
    Sander Veldhuyzen van Zanten
    Dalhousie Medical School, Queen Elizabeth II Health Sciences Centre, Halifax, Nova Scotia, Canada
    Can J Gastroenterol 18:749-50. 2004
  9. ncbi request reprint Validation of a 7-point Global Overall Symptom scale to measure the severity of dyspepsia symptoms in clinical trials
    S J O Veldhuyzen van Zanten
    Division of Gastroenterology, Dalhousie University, Halifax, NS, Canada
    Aliment Pharmacol Ther 23:521-9. 2006
  10. ncbi request reprint A randomized trial comparing seven-day ranitidine bismuth citrate and clarithromycin dual therapy to seven-day omeprazole, clarithromycin and amoxicillin triple therapy for the eradication of Helicobacter pylori
    Sander Veldhuyzen van Zanten
    Dalhousie University, Department of Medicine, Halifax, Nova Scotia, Canada
    Can J Gastroenterol 17:533-8. 2003

Collaborators

  • R H Hunt
  • Y Chen
  • Richard N Fedorak
  • J Lee
  • A Thomson
  • S Daniels
  • C A Fallone
  • I K Wiklund
  • H J Schünemann
  • G Sachs
  • F Camacho
  • G H Guyatt
  • N W Flook
  • Alan G Casson
  • Geoffrey A Porter
  • Joachim Labenz
  • Paul Veugelers
  • Alan N Barkun
  • A Lanas
  • D Armstrong
  • S J O Veldhuyzen van Zanten
  • Naoki Chiba
  • N Chiba
  • David Armstrong
  • Samer El-Dika
  • S Escobedo
  • Thomas W Lee
  • Clarence K W Wong
  • Sander Veldhuyzen van Zanten
  • P Sinclair
  • S Veldhuyzen Van Zanten
  • Robert Flook
  • D Leddin
  • Neville Yeomans
  • Alex Mitchell
  • E F Verdu
  • Christopher Rodgers
  • B Chakraborty
  • R J White
  • J Zacny
  • Z Dyer
  • Sander J O Veldhuyzen van Zanten
  • Alessio Degl' Innocenti
  • C James
  • Peggy Austin
  • Lisa Tanser
  • Diane Heels-Ansdell
  • K Nevin
  • Marianne E Stewart
  • Connie I Prosser
  • Michael R Kolber
  • Daniel C Sadowski
  • J K Marshall
  • S J Veldhuyzen van Zanten
  • Konstantin Tchernev
  • Lars Erik Svedberg
  • Christoffel Van Rensburg
  • Istvan Racz
  • Karen Inglis
  • Dimitrios Karamanolis
  • W G Paterson
  • Emma Nauclér
  • R Hollingworth
  • Enrico Roda
  • Chris Hawkey
  • R Enns
  • T Ponich
  • J Romagnuolo
  • B Teixeira
  • F A Husein-Bhabha
  • J Bourgeois
  • G L A Horbay
  • J Springer
  • M Mauro
  • V Mann
  • I Sketris
  • K Peltekian
  • M Zamakhshary
  • S Smyth
  • Marc Bradette
  • Ford Bursey
  • Alessio degl'Innocenti
  • Peter Wahlqvist
  • D Bair
  • Lorinda Simms
  • Alain Farley
  • Chrystian Dallaire
  • Barbara Nicholls
  • L Tanser
  • Alan Cockeram

Detail Information

Publications41

  1. pmc The influence of demographic factors and health-related quality of life on treatment satisfaction in patients with gastroesophageal reflux disease treated with esomeprazole
    Alessio Degl' Innocenti
    AstraZeneca R and D, 431 83 Mölndal, Sweden
    Health Qual Life Outcomes 3:4. 2005
    ..The objective of this study was to assess correlates of treatment satisfaction in patients with GERD receiving a proton pump inhibitor, esomeprazole...
  2. pmc The impact of illness in patients with moderate to severe gastro-esophageal reflux disease
    Samer El-Dika
    Division of Gastroenterology, Veterans Affairs Medical Center, Salem, Virginia, USA
    BMC Gastroenterol 5:23. 2005
    ..Gastro-esophageal reflux disease (GERD) is a common disease. It impairs health related quality of life (HRQL). However, the impact on utility scores and work productivity in patients with moderate to severe GERD is not well known...
  3. ncbi request reprint One-week triple therapy with esomeprazole, clarithromycin and metronidazole provides effective eradication of Helicobacter pylori infection
    S Veldhuyzen Van Zanten
    Division of Gastroenterology, Department of Medicine, Dalhousie University, Halifax, Canada
    Aliment Pharmacol Ther 17:1381-7. 2003
    ..omeprazole, metronidazole and clarithromycin (OMC), given for 7 days. OMC treatment was followed by 3 weeks of treatment with 20 mg omeprazole alone; the EMC group received placebo...
  4. ncbi request reprint The prevalence of Barrett's oesophagus in a cohort of 1040 Canadian primary care patients with uninvestigated dyspepsia undergoing prompt endoscopy
    S J O Veldhuyzen van Zanten
    Division of Gastroenterology, Dalhousie University, Halifax, NS, Canada
    Aliment Pharmacol Ther 23:595-9. 2006
    ..The prevalence of Barrett's oesophagus in patients undergoing gastroscopy may be influenced by possible referral bias...
  5. ncbi request reprint Upper gastrointestinal alarms: the 2-week rule
    Sander Veldhuyzen van Zanten
    Queen Elizabeth II Health Sciences Center, Victoria General Hospital Site, Halifax, Nova Scotia, B3H 2Y9, Canada
    Lancet 365:2163-4. 2005
  6. ncbi request reprint Review article: the changing epidemiology of hepatocellular carcinoma in Canada
    Z Dyer
    Department of Medicine, Queen Elizabeth II Health Sciences Center, Dalhousie University, Halifax, NS, Canada
    Aliment Pharmacol Ther 22:17-22. 2005
    ..The incidence of hepatocellular carcinoma in Canada has increased in the past 20 years and is associated with a rise in the incidence of hepatitis C, obesity and diabetes...
  7. ncbi request reprint Systematic review: the efficacy of intermittent and on-demand therapy with histamine H2-receptor antagonists or proton pump inhibitors for gastro-oesophageal reflux disease patients
    J Zacny
    Division of Gastroenterology, Queen Elizabeth II Health Sciences Centre, Halifax, Nova Scotia, Canada
    Aliment Pharmacol Ther 21:1299-312. 2005
    ..To perform a systematic review on the efficacy of intermittent and on-demand therapy with either histamine H2-receptor antagonists or proton pump inhibitors for patients with erosive oesophagitis or symptomatic heartburn...
  8. ncbi request reprint Cost-effectiveness of intravenous proton pump inhibitors in high-risk bleeders
    Sander Veldhuyzen van Zanten
    Dalhousie Medical School, Queen Elizabeth II Health Sciences Centre, Halifax, Nova Scotia, Canada
    Can J Gastroenterol 18:749-50. 2004
  9. ncbi request reprint Validation of a 7-point Global Overall Symptom scale to measure the severity of dyspepsia symptoms in clinical trials
    S J O Veldhuyzen van Zanten
    Division of Gastroenterology, Dalhousie University, Halifax, NS, Canada
    Aliment Pharmacol Ther 23:521-9. 2006
    ..Currently there is no consensus on the optimal method to measure the severity of dyspepsia symptoms in clinical trials...
  10. ncbi request reprint A randomized trial comparing seven-day ranitidine bismuth citrate and clarithromycin dual therapy to seven-day omeprazole, clarithromycin and amoxicillin triple therapy for the eradication of Helicobacter pylori
    Sander Veldhuyzen van Zanten
    Dalhousie University, Department of Medicine, Halifax, Nova Scotia, Canada
    Can J Gastroenterol 17:533-8. 2003
    ..To assess Helicobacter pylori eradication after one week dual ranitidine bismuth citrate-clarithromycin (RBC-C) or triple omeprazole, clarithromycin and amoxicillin (OCA) therapy...
  11. ncbi request reprint Evidence-based recommendations for short- and long-term management of uninvestigated dyspepsia in primary care: an update of the Canadian Dyspepsia Working Group (CanDys) clinical management tool
    Sander J O Veldhuyzen van Zanten
    Division of Gastroenterology, Dalhousie Medical School, Dalhousie University, Queen Elizabeth II Health Sciences Centre, 1278 Tower Road, Halifax, Nova Scotia B3H 2Y9, Canada
    Can J Gastroenterol 19:285-303. 2005
    ..When starting nonsteroidal anti-inflammatory drugs for a prolonged course, testing and treatment with H2RAs are advised if patients have a history of previous ulcers or ulcer bleeding...
  12. ncbi request reprint Heartburn-dominant, uninvestigated dyspepsia: a comparison of 'PPI-start' and 'H2-RA-start' management strategies in primary care--the CADET-HR Study
    D Armstrong
    Division of Gastroenterology, McMaster University, Hamilton, Ontario, Canada
    Aliment Pharmacol Ther 21:1189-202. 2005
    ..There are few data on empiric, stepped therapy for heartburn relief or subsequent relapse in primary care...
  13. ncbi request reprint Esomeprazole 40 mg once a day in patients with functional dyspepsia: the randomized, placebo-controlled "ENTER" trial
    Sander Veldhuyzen van Zanten
    Division of Gastroenterology, Dalhousie University, Halifax, Canada
    Am J Gastroenterol 101:2096-106. 2006
    ..The objective of this study was to evaluate the efficacy of esomeprazole 40 mg once a day compared to placebo in achieving symptom relief in primary care patients with FD...
  14. ncbi request reprint Symptom relief in gastroesophageal reflux disease: a randomized, controlled comparison of pantoprazole and nizatidine in a mixed patient population with erosive esophagitis or endoscopy-negative reflux disease
    D Armstrong
    Division of Gastroenterology, McMaster University, Hamilton, Ontario, Canada
    Am J Gastroenterol 96:2849-57. 2001
    ..The present study data suggest that pantoprazole is a highly effective first-line therapy for the management of gastroesophageal reflux disease in a primary care practice setting...
  15. ncbi request reprint Symptom overlap in patients with upper gastrointestinal complaints in the Canadian confirmatory acid suppression test (CAST) study: further psychometric validation of the reflux disease questionnaire
    S V Van Zanten
    Division of Gastroenterology, Department of Medicine, University of Alberta, Edmonton, AB, Canada
    Aliment Pharmacol Ther 25:1087-97. 2007
    ..The reflux disease questionnaire (RDQ) is a short, patient-completed instrument...
  16. pmc An evidence-based approach to the management of uninvestigated dyspepsia in the era of Helicobacter pylori. Canadian Dyspepsia Working Group
    S J Veldhuyzen van Zanten
    Department of Medicine, Queen Elizabeth II Health Sciences Centre, Dalhousie University, Halifax, NS
    CMAJ 162:S3-23. 2000
    ..To provide Canadian primary care physicians with an evidence-based clinical management tool, including diagnostic and treatment recommendations, for patients who present with uninvestigated dyspepsia...
  17. ncbi request reprint Oral rabeprazole vs. intravenous pantoprazole: a comparison of the effect on intragastric pH in healthy subjects
    D Armstrong
    Division of Gastroenterology, McMaster University, Hamilton, ON, Canada
    Aliment Pharmacol Ther 25:185-96. 2007
    ..Intravenous pantoprazole is often administered inappropriately to hospitalized patients who can take oral medications...
  18. doi request reprint The pharmacodynamics and pharmacokinetics of S-tenatoprazole-Na 30 mg, 60 mg and 90 mg vs. esomeprazole 40 mg in healthy male subjects
    R H Hunt
    Farncombe Family Digestive Disease Research Institute, Division of Gastroenterology, McMaster University and Hamilton Health Sciences, Hamilton, ON, Canada
    Aliment Pharmacol Ther 31:648-57. 2010
    ..Racemic tenatoprazole 40 mg/day provides more prolonged acid suppression than esomeprazole 40 mg/day...
  19. ncbi request reprint Test and treat strategies for Helicobacter pylori in uninvestigated dyspepsia: a Canadian economic analysis
    J K Marshall
    Division of Gastroenterology, McMaster University Medical Centre, Hamilton, Ontario, Canada
    Can J Gastroenterol 14:379-88. 2000
    ..Decision analysis was used to compare the cost effectiveness of empirical ranitidine with a test and treat strategy using either H pylori serology or the 13carbon-urea breath test (13C-UBT)...
  20. doi request reprint Gastric ulcer treatment: cure of Helicobacter pylori infection without subsequent acid-suppressive therapy: is it effective?
    Sander Veldhuyzen van Zanten
    Division of Gastroenterology, University of Alberta, Zeidler Ledcor Centre, Edmonton, Alberta, Canada
    Eur J Gastroenterol Hepatol 20:489-91. 2008
    ..This is certainly recommended when dealing with bleeding ulcers...
  21. ncbi request reprint Oral esomeprazole vs. intravenous pantoprazole: a comparison of the effect on intragastric pH in healthy subjects
    D Armstrong
    Division of Gastroenterology, McMaster University and Hamilton Health Sciences, Hamilton, ON, Canada
    Aliment Pharmacol Ther 18:705-11. 2003
    ..Oral esomeprazole produces greater acid suppression than oral pantoprazole; however, no comparative data exist for oral esomeprazole and i.v. pantoprazole...
  22. doi request reprint Predictable prolonged suppression of gastric acidity with a novel proton pump inhibitor, AGN 201904-Z
    R H Hunt
    Division of Gastroenterology, McMaster University and Hamilton Health Science Centre, Hamilton, ON, Canada
    Aliment Pharmacol Ther 28:187-99. 2008
    ..AGN 201904-Z is a new, slowly absorbed, acid-stable pro-proton pump inhibitor (pro-PPI) rapidly converted to omeprazole in the systemic circulation giving a prolonged residence time...
  23. pmc A meta-analysis of the success rate of Helicobacter pylori therapy in Canada
    Christopher Rodgers
    Division of Gastroenterology, University of Alberta, Edmonton, Canada
    Can J Gastroenterol 21:295-300. 2007
    ..Helicobacter pylori treatment success rates have varied. A systematic review of the success rate of anti- H pylori therapy in Canada was performed...
  24. ncbi request reprint Do physicians correctly assess patient symptom severity in gastro-oesophageal reflux disease?
    C A Fallone
    Division of Gastroenterology, McGill University Health Center, Montreal, QC, Canada
    Aliment Pharmacol Ther 20:1161-9. 2004
    ..The accuracy of physicians' assessment of the severity of gastro-oesophageal reflux disease is unclear...
  25. ncbi request reprint Review article: gastric pH -- the most relevant predictor of benefit in reflux disease?
    D Armstrong
    Division of Gastroenterology, McMaster University, Hamilton, Ontario, Canada
    Aliment Pharmacol Ther 20:19-26; discussion 38-9. 2004
    ..These data all suggest strongly that intragastric pH monitoring is an effective surrogate marker and a relevant predictor of outcome in gastro-oesophageal reflux disease...
  26. pmc Pancreatic cancer in Canada: incidence and mortality trends from 1992 to 2005
    Robert Flook
    Division of Gastroenterology, University of Alberta, Edmonton, Canada
    Can J Gastroenterol 23:546-50. 2009
    ..Pancreatic cancer is the fourth-ranking cause of death among all major malignancies in Canada and has the lowest five-year survival rate...
  27. pmc Endoscopic evaluation of gastro-esophageal reflux disease
    D Armstrong
    Division of Gastroenterology, McMaster University Medical Centre, Hamilton, Ontario, Canada
    Yale J Biol Med 72:93-100. 1999
    ..Non-erosive changes such as erythema may be ignored on the basis of present evidence, and there are no clear data to support the use of endoscopic biopsies for the diagnosis of GERD...
  28. pmc Canadian credentialing guidelines for endoscopic privileges: an overview
    D Armstrong
    Division of Gastroenterology, McMaster University, Hamilton, Canada
    Can J Gastroenterol 21:797-801. 2007
  29. doi request reprint Systematic review: persistence and severity in gastro-oesophageal reflux disease
    D Armstrong
    Division of Gastroenterology, McMaster University, Hamilton, ON, Canada
    Aliment Pharmacol Ther 28:841-53. 2008
    ..Management strategies for gastro-oesophageal reflux disease (GERD) are often inconsistent with the proposition that it is a persistent or chronic disease...
  30. doi request reprint Iron replacement therapy in inflammatory bowel disease patients with iron deficiency anemia: a systematic review and meta-analysis
    Thomas W Lee
    Division of Gastroenterology, Center of Excellence for Gastrointestinal Inflammation and Immunity Research CEGIIR, University of Alberta, Alberta, Canada
    J Crohns Colitis 6:267-75. 2012
    ..The aim was to compare the clinical efficacy of intravenous (IV) versus oral (PO) iron replacement in adult IBD with iron deficiency anemia (IDA)...
  31. ncbi request reprint Cyclin D1 polymorphism (G870A) and risk for esophageal adenocarcinoma
    Alan G Casson
    Department of Surgery, Division of Thoracic Surgery, Dalhousie University, Halifax, Nova Scotia, Canada
    Cancer 104:730-9. 2005
    ....
  32. pmc Access to specialist gastroenterology care in Canada: comparison of wait times and consensus targets
    D Leddin
    Dalhousie University, Halifax, Nova Scotia, Canada
    Can J Gastroenterol 22:161-7. 2008
    ..The present study compared wait times for specialist gastroenterology care with recent, evidence-based, consensus-defined benchmark wait times for a range of digestive diseases...
  33. ncbi request reprint Review article: towards consistency in the endoscopic diagnosis of Barrett's oesophagus and columnar metaplasia
    D Armstrong
    Division of Gastroenterology, McMaster University, Hamilton, Ontario, Canada
    Aliment Pharmacol Ther 20:40-7; discussion 61-2. 2004
    ..It is hoped that these propositions will be the first step in the development of standard endoscopic diagnostic criteria for Barrett's oesophagus, relevant to clinical practice and clinical research...
  34. doi request reprint The sensitivity and specificity of guaiac and immunochemical fecal occult blood tests for the detection of advanced colonic adenomas and cancer
    Clarence K W Wong
    Division of Gastroenterology, Royal Alexandra Hospital, 10240 Kingsway Ave, Edmonton, AB, T5H 3V9, Canada
    Int J Colorectal Dis 27:1657-64. 2012
    ..We also examined whether a 1-day collection strategy would negatively impact test diagnostic performance...
  35. doi request reprint A randomized controlled trial comparing acetaminophen plus ibuprofen versus acetaminophen plus codeine plus caffeine after outpatient general surgery
    Alex Mitchell
    Department of Surgery, Dalhousie University and QEII Health Sciences Centre, Halifax, Nova Scotia, Canada
    J Am Coll Surg 206:472-9. 2008
    ..The objective of this study was to compare the efficacy of acetaminophen, codeine, and caffeine (Tylenol No. 3) with acetaminophen and ibuprofen for management of pain after outpatient general surgery procedures...
  36. pmc Clinical onset of celiac disease after an episode of Campylobacter jejuni enteritis
    E F Verdu
    Intestinal Disease Research Program, Division of Gastroenterology, McMaster University Medical Centre, Hamilton, Ontario, Canada
    Can J Gastroenterol 21:453-5. 2007
    ..The present case findings suggest that CD should be considered in the differential diagnosis of persistent IBS-like symptoms after an episode of infectious gastroenteritis...
  37. doi request reprint Efficacy of esomeprazole (20 mg once daily) for reducing the risk of gastroduodenal ulcers associated with continuous use of low-dose aspirin
    Neville Yeomans
    School of Medicine, University of Western Sydney, Sydney, Australia
    Am J Gastroenterol 103:2465-73. 2008
    ..This study determined the efficacy of esomeprazole for reducing the risk of gastric and/or duodenal ulcers and dyspeptic symptoms in patients receiving continuous, low-dose aspirin therapy...
  38. ncbi request reprint A randomized multicenter trial to evaluate simple utility elicitation techniques in patients with gastroesophageal reflux disease
    Holger J Schunemann
    Department of Medicine, School of Medicine and Biomedical Sciences, University at Buffalo, State University of New York, Buffalo, New York, USA
    Med Care 42:1132-42. 2004
    ..We evaluated whether the administration of marker states improves measurement properties of the FT and SG...
  39. ncbi request reprint Should the presence of polymorphisms of CYP2C19 enzymes influence the choice of the proton pump inhibitor for treatment of Helicobacter pylori infection?
    Sander Veldhuyzen van Zanten
    Am J Gastroenterol 101:1476-8. 2006
    ..Study quality was suboptimal and other factors such as resistance to antibiotics may explain the observed differences in success rates. More clinical trial data are needed before we can accept the conclusions of this meta-analysis...
  40. ncbi request reprint Diagnosing irritable bowel syndrome
    Sander Veldhuyzen van Zanten
    Department of Medicine, Division of Gastroenterology, Dalhousie University, QEII Health Sciences Centre, Halifax, Nova Scotia, Canada
    Rev Gastroenterol Disord 3:S12-7. 2003
    ..An interactive, positive physician-patient relationship has a beneficial effect on the course of IBS and may be associated with a decreased need for future health care visits...
  41. ncbi request reprint Failure to define what constitutes a patient responder is a problem in the interpretation of the probiotic clinical trial evaluating the use of Bifidobacterium in irritable bowel syndrome
    Sander Veldhuyzen van Zanten
    Gastroenterology 129:772; author 772-3. 2005