A S MacDonald

Summary

Affiliation: Dalhousie University
Country: Canada

Publications

  1. ncbi request reprint A clinical pharmacokinetic study of tacrolimus and sirolimus combination immunosuppression comparing simultaneous to separated administration
    Vivian C McAlister
    Department of Surgery, Dalhousie University, Halifax, Nova Scotia, Canada
    Ther Drug Monit 24:346-50. 2002
  2. ncbi request reprint Use of mTOR inhibitors in human organ transplantation
    Allan S MacDonald
    Professor of Surgery, Dalhousie University, Halifax, Nova Scotia Cumberland Regional Health Care Centre, 19428 Hgwy 2, Upper Nappan, Nova Scotia B4H 1N6, Canada
    Expert Rev Clin Immunol 3:423-36. 2007
  3. ncbi request reprint Cancer and transplantation intersect at the mammalian target of rapamycin
    Allan S MacDonald
    Department of Surgery, Dalhousie University Halifax, Nova Scotia, Canada
    Transplantation 84:682-4. 2007
  4. ncbi request reprint Increasing demand, decreasing resources: provision of transplantation services in Canada's single payer health system
    A S Mac Donald
    Dalhousie University, Queen Elizabeth II Health Sciences Centre, Victoria Building, Room 8 805 1278 Tower Road, Halifax, NS, B3H 2Y9
    Transplant Proc 35:1230-2. 2003
  5. ncbi request reprint Rapamycin in combination with cyclosporine or tacrolimus in liver, pancreas, and kidney transplantation
    A S MacDonald
    Department of Surgery, Dalhousie University, Halifax, Nova Scotia, Canada
    Transplant Proc 35:201S-208S. 2003
  6. ncbi request reprint Orthotopic liver transplantation using low-dose tacrolimus and sirolimus
    V C McAlister
    Atlantic Canada Liver Transplantation Program, Dalhousie University, Halifax, Nova Scotia, Canada
    Liver Transpl 7:701-8. 2001
  7. ncbi request reprint A worldwide, phase III, randomized, controlled, safety and efficacy study of a sirolimus/cyclosporine regimen for prevention of acute rejection in recipients of primary mismatched renal allografts
    A S MacDonald
    Dalhousie University, Halifax, Nova Scotia, Canada
    Transplantation 71:271-80. 2001
  8. ncbi request reprint Approaching the therapeutic window for cyclosporine in kidney transplantation: a prospective study
    K Mahalati
    Kidney Transplant Program and the Department of Urology, Queen Elizabeth II Health Sciences Centre, 1278 Tower Road, Halifax, Nova Scotia B3H 2Y9, Canada
    J Am Soc Nephrol 12:828-33. 2001
  9. ncbi request reprint The role of psychological functioning in morbid obesity and its treatment with gastroplasty
    T M Vallis
    Queen Elizabeth II Health Sciences Centre, Dalhousie University, Halifax, NS, Canada
    Obes Surg 11:716-25. 2001
  10. ncbi request reprint The Obesity Adjustment Survey: development of a scale to assess psychological adjustment to morbid obesity
    G S Butler
    Queen Elizabeth II Health Sciences Centre and Dalhousie University, Halifax, NS, Canada
    Int J Obes Relat Metab Disord 23:505-11. 1999

Collaborators

  • Jim R Wright
  • Vivian C McAlister
  • Zu hua Gao
  • Chloe C McAlister
  • T M Vallis
  • G S Butler
  • Kevork Peltekian
  • A S Mac Donald
  • V C McAlister
  • K Mahalati
  • G Konok
  • S J Veldhuyzen van Zanten
  • B Perey
  • Rekha Gupta
  • Kevork M Peltekian
  • Kamran Mahalati
  • Albert Fraser
  • J Lawen
  • D A Malatjalian
  • H Bitter-Suermann
  • V McAlister
  • I Sketris
  • K West
  • A Fraser
  • P Belitsky
  • B Kiberd
  • S Macdonald
  • K M Peltekian
  • S Colohan

Detail Information

Publications12

  1. ncbi request reprint A clinical pharmacokinetic study of tacrolimus and sirolimus combination immunosuppression comparing simultaneous to separated administration
    Vivian C McAlister
    Department of Surgery, Dalhousie University, Halifax, Nova Scotia, Canada
    Ther Drug Monit 24:346-50. 2002
    ..These data confirm that simultaneous dosing of TAC and SRL after transplantation is safe and that trough level monitoring is adequate to control therapy...
  2. ncbi request reprint Use of mTOR inhibitors in human organ transplantation
    Allan S MacDonald
    Professor of Surgery, Dalhousie University, Halifax, Nova Scotia Cumberland Regional Health Care Centre, 19428 Hgwy 2, Upper Nappan, Nova Scotia B4H 1N6, Canada
    Expert Rev Clin Immunol 3:423-36. 2007
    ..Their ability to reduce fibrosis and neovascularization suggests other areas of potential use...
  3. ncbi request reprint Cancer and transplantation intersect at the mammalian target of rapamycin
    Allan S MacDonald
    Department of Surgery, Dalhousie University Halifax, Nova Scotia, Canada
    Transplantation 84:682-4. 2007
  4. ncbi request reprint Increasing demand, decreasing resources: provision of transplantation services in Canada's single payer health system
    A S Mac Donald
    Dalhousie University, Queen Elizabeth II Health Sciences Centre, Victoria Building, Room 8 805 1278 Tower Road, Halifax, NS, B3H 2Y9
    Transplant Proc 35:1230-2. 2003
  5. ncbi request reprint Rapamycin in combination with cyclosporine or tacrolimus in liver, pancreas, and kidney transplantation
    A S MacDonald
    Department of Surgery, Dalhousie University, Halifax, Nova Scotia, Canada
    Transplant Proc 35:201S-208S. 2003
    ..The lessons learned include the need for early adequate blood levels, the lack of correlation between dose and drug exposure, and the potency that allows marked dose reductions in calcineurin inhibitors and steroids...
  6. ncbi request reprint Orthotopic liver transplantation using low-dose tacrolimus and sirolimus
    V C McAlister
    Atlantic Canada Liver Transplantation Program, Dalhousie University, Halifax, Nova Scotia, Canada
    Liver Transpl 7:701-8. 2001
    ..A low-dose combination of SRL and TAC should be compared with conventional immunosuppression in a multicenter, randomized, controlled trial...
  7. ncbi request reprint A worldwide, phase III, randomized, controlled, safety and efficacy study of a sirolimus/cyclosporine regimen for prevention of acute rejection in recipients of primary mismatched renal allografts
    A S MacDonald
    Dalhousie University, Halifax, Nova Scotia, Canada
    Transplantation 71:271-80. 2001
    ....
  8. ncbi request reprint Approaching the therapeutic window for cyclosporine in kidney transplantation: a prospective study
    K Mahalati
    Kidney Transplant Program and the Department of Urology, Queen Elizabeth II Health Sciences Centre, 1278 Tower Road, Halifax, Nova Scotia B3H 2Y9, Canada
    J Am Soc Nephrol 12:828-33. 2001
    ..Attainment of a target range of 4400 to 5500 microg/h per L for AUC(0-4) early after transplantation has been demonstrated to reduce significantly the risk of AR and CyANT...
  9. ncbi request reprint The role of psychological functioning in morbid obesity and its treatment with gastroplasty
    T M Vallis
    Queen Elizabeth II Health Sciences Centre, Dalhousie University, Halifax, NS, Canada
    Obes Surg 11:716-25. 2001
    ..The role that these psychological characteristics play in moderating the success of gastroplasty surgery, as well as the impact of surgery on quality of life, was examined...
  10. ncbi request reprint The Obesity Adjustment Survey: development of a scale to assess psychological adjustment to morbid obesity
    G S Butler
    Queen Elizabeth II Health Sciences Centre and Dalhousie University, Halifax, NS, Canada
    Int J Obes Relat Metab Disord 23:505-11. 1999
    ..To develop a reliable and valid measure of distress, related to extreme obesity...
  11. ncbi request reprint Protective anti-donor IgM production after crossmatch positive liver-kidney transplantation
    Chloe C McAlister
    Department of Medicine, Dalhousie University, Halifax, Nova Scotia, Canada
    Liver Transpl 10:315-9. 2004
    ..We report a crossmatch-positive LKT where posttransplantation production of IgM DSA, which failed to fix complement, appeared to protect the grafts...
  12. ncbi request reprint Immunoglobulin-G subclass antidonor reactivity in transplant recipients
    Zu hua Gao
    Department of Surgery, Dalhousie University, Halifax, Nova Scotia, Canada
    Liver Transpl 10:1055-9. 2004
    ..A late rise in antidonor IgG4 is consistent with decreased antidonor reactivity thought to occur late after transplantation...