Centre for Addiction and Mental Health

Summary

Organization: Centre for Addiction and Mental Health
Country: Canada

Top Publications

  1. doi Genetic and pharmacological evidence that 5-HT2C receptor activation, but not inhibition, affects motivation to feed under a progressive ratio schedule of reinforcement
    Paul J Fletcher
    Section of Biopsychology, Centre for Addiction and Mental Health, Toronto, Ontario, Canada
    Pharmacol Biochem Behav 97:170-8. 2010
  2. ncbi Understanding the parameters of non-medical use of prescription drugs: moving beyond mere numbers
    Benedikt Fischer
    University of Victoria, Canada
    Addiction 102:1931-2. 2007
  3. ncbi A national survey of primary methamphetamine-related admissions to youth residential substance abuse treatment facilities in Canada, 2005 to 2006
    Russell C Callaghan
    Centre for Addiction and Mental Health, Toronto, Ontario
    Can J Psychiatry 52:684-8. 2007
  4. pmc The chronobiology and neurobiology of winter seasonal affective disorder
    Robert D Levitan
    Department of Psychiatry, University of Toronto, Canada
    Dialogues Clin Neurosci 9:315-24. 2007
  5. ncbi Psychopharmacologic management of suicidality in personality disorders
    Robert J Cardish
    Borderline Personality Disorder Clinic, Centre for Addiction and Mental Health, Toronto, Ontario
    Can J Psychiatry 52:115S-127S. 2007
  6. ncbi Clozapine-induced hypersalivation: a review of treatment strategies
    Sanjeev Sockalingam
    Department of Psychiatry, University of Toronto, Ontario
    Can J Psychiatry 52:377-84. 2007
  7. ncbi Integrated online services for smokers and drinkers? Use of the check your drinking assessment screener by participants of the Stop Smoking Center
    John A Cunningham
    Centre for Addiction and Mental Health and University of Toronto, Canada
    Nicotine Tob Res 8:S21-5. 2006
  8. ncbi Is readmission a valid indicator of the quality of inpatient psychiatric care?
    Janet Durbin
    Health Systems Research and Consulting Unit, Centre for Addiction and Mental Health, University of Toronto, 33 Russell Street, T310, Toronto, ON, M5S 2S1, Canada
    J Behav Health Serv Res 34:137-50. 2007
  9. ncbi Conditioned dopamine release in humans: a positron emission tomography [11C]raclopride study with amphetamine
    Isabelle Boileau
    McConnell Brain Imaging Center, Montreal Neurological Institute, Montreal, Quebec, Canada H3A 2B4
    J Neurosci 27:3998-4003. 2007
  10. ncbi Health service utilization by Ethiopian immigrants and refugees in Toronto
    Haile Fenta
    Social Equity and Health Research, Centre for Addiction and Mental Health, Toronto, ON, Canada
    J Immigr Minor Health 9:349-57. 2007

Research Grants

Detail Information

Publications62

  1. doi Genetic and pharmacological evidence that 5-HT2C receptor activation, but not inhibition, affects motivation to feed under a progressive ratio schedule of reinforcement
    Paul J Fletcher
    Section of Biopsychology, Centre for Addiction and Mental Health, Toronto, Ontario, Canada
    Pharmacol Biochem Behav 97:170-8. 2010
    ....
  2. ncbi Understanding the parameters of non-medical use of prescription drugs: moving beyond mere numbers
    Benedikt Fischer
    University of Victoria, Canada
    Addiction 102:1931-2. 2007
  3. ncbi A national survey of primary methamphetamine-related admissions to youth residential substance abuse treatment facilities in Canada, 2005 to 2006
    Russell C Callaghan
    Centre for Addiction and Mental Health, Toronto, Ontario
    Can J Psychiatry 52:684-8. 2007
    ..The objective of the current study was to provide results from a national survey of primary methamphetamine-related admissions to Canadian residential substance abuse treatment facilities for youth...
  4. pmc The chronobiology and neurobiology of winter seasonal affective disorder
    Robert D Levitan
    Department of Psychiatry, University of Toronto, Canada
    Dialogues Clin Neurosci 9:315-24. 2007
    ..Models of SAD that emphasize its potential role in human evolution will also be discussed...
  5. ncbi Psychopharmacologic management of suicidality in personality disorders
    Robert J Cardish
    Borderline Personality Disorder Clinic, Centre for Addiction and Mental Health, Toronto, Ontario
    Can J Psychiatry 52:115S-127S. 2007
    ..To review the evidence for the efficacy of pharmacotherapy and other biological treatments in suicidality associated with personality disorders, chiefly borderline personality disorder...
  6. ncbi Clozapine-induced hypersalivation: a review of treatment strategies
    Sanjeev Sockalingam
    Department of Psychiatry, University of Toronto, Ontario
    Can J Psychiatry 52:377-84. 2007
    ..The purpose of this review is to provide an understanding of CIH, specifically, its pathophysiology, measurement, and the evidence for CIH treatment alternatives...
  7. ncbi Integrated online services for smokers and drinkers? Use of the check your drinking assessment screener by participants of the Stop Smoking Center
    John A Cunningham
    Centre for Addiction and Mental Health and University of Toronto, Canada
    Nicotine Tob Res 8:S21-5. 2006
    ..This brief report will explore the implications of the overlap of smoking and drinking by these online participants and will discuss the potential benefits of providing an integrated service for smokers and problem drinkers...
  8. ncbi Is readmission a valid indicator of the quality of inpatient psychiatric care?
    Janet Durbin
    Health Systems Research and Consulting Unit, Centre for Addiction and Mental Health, University of Toronto, 33 Russell Street, T310, Toronto, ON, M5S 2S1, Canada
    J Behav Health Serv Res 34:137-50. 2007
    ....
  9. ncbi Conditioned dopamine release in humans: a positron emission tomography [11C]raclopride study with amphetamine
    Isabelle Boileau
    McConnell Brain Imaging Center, Montreal Neurological Institute, Montreal, Quebec, Canada H3A 2B4
    J Neurosci 27:3998-4003. 2007
    ..These results suggest that cues associated with amphetamine increase dopamine transmission, providing evidence that this system is involved in reward prediction in humans...
  10. ncbi Health service utilization by Ethiopian immigrants and refugees in Toronto
    Haile Fenta
    Social Equity and Health Research, Centre for Addiction and Mental Health, Toronto, ON, Canada
    J Immigr Minor Health 9:349-57. 2007
    ..Further research is necessary to determine the reasons for the low rates of mental health services use in this population...
  11. ncbi Changes in autobiographical memory specificity following cognitive behavior therapy and pharmacotherapy for major depression
    Carolina McBride
    Centre for Addiction and Mental Health, Toronto, Ontario, Canada
    Psychopathology 40:147-52. 2007
    ..Overgeneral memory is considered as a stable cognitive trait that is intrinsically linked with depression and independent of mood state. Previous studies show that autobiographical memory is modifiable...
  12. ncbi Rodent models: utility for candidate gene studies in human attention-deficit hyperactivity disorder (ADHD)
    Jonathan Mill
    Centre for Addiction and Mental Health, Toronto, Canada
    J Neurosci Methods 166:294-305. 2007
    ....
  13. pmc A glossary for the social epidemiology of work organisation: part 1, terms from social psychology
    C Muntaner
    Social Equity and Health Section, Center for Association and Mental Health, University of Toronto, Ontario, Canada
    J Epidemiol Community Health 60:914-6. 2006
  14. ncbi Serotonin 2A receptor gene is associated with personality traits, but not to disorder, in patients with borderline personality disorder
    Xingqun Ni
    Neurogenetics Section, Centre for Addiction and Mental Health, Toronto, Ont M5T 1R8, Canada
    Neurosci Lett 408:214-9. 2006
    ..Our results suggest that the serotonin 2A receptor gene may not play a major role in the aetiology of borderline personality disorder, but may have a role in personality traits...
  15. doi Increased cortical inhibition in persons with schizophrenia treated with clozapine
    Zafiris J Daskalakis
    Centre for Addiction and Mental Health, University of Toronto, Toronto, Ontario, Canada
    J Psychopharmacol 22:203-9. 2008
    ..Our results also confirm previous findings suggesting that deficits in CI are related to the severity of psychotic symptoms in persons with schizophrenia...
  16. doi Recovery and URICA stage-of-change scores in three marijuana treatment studies
    Russell C Callaghan
    Department of Public Health Sciences, Centre for Addiction and Mental Health, University of Toronto, Canada
    J Subst Abuse Treat 35:419-26. 2008
    ..Better methods to measure stage status and test the TMC are needed if the model is to be used to guide substance abuse interventions...
  17. ncbi Negative life events and age-related decline in mastery: are older adults more vulnerable to the control-eroding effect of stress?
    John Cairney
    Health Systems Research and Consulting Unit, Centre for Addiction and Mental Health, Toronto, Ontario, Canada
    J Gerontol B Psychol Sci Soc Sci 63:S162-70. 2008
    ..The purpose of this study was to see if exposure to life events influences age-related decline in control...
  18. pmc Decreased cerebral cortical serotonin transporter binding in ecstasy users: a positron emission tomography/[(11)C]DASB and structural brain imaging study
    Stephen J Kish
    Human Neurochemical Pathology Laboratory, Centre for Addiction and Mental Health, 250 College Street, Toronto, Ontario M5T 1R8, Canada
    Brain 133:1779-97. 2010
    ....
  19. pmc A season-of-birth/DRD4 interaction predicts maximal body mass index in women with bulimia nervosa
    Robert D Levitan
    Mood and Anxiety Division, Department of Psychiatry, Centre for Addiction and Mental Health, University of Toronto, Toronto, ON, Canada
    Neuropsychopharmacology 35:1729-33. 2010
    ..9 vs 8.8%, respectively, p=0.008). These data offer further evidence that season of birth interacts with the 7R allele of DRD4 to influence body weight regulation in female overeating populations...
  20. doi The DSM diagnostic criteria for pedophilia
    Ray Blanchard
    Kurt Freund Laboratory, Law and Mental Health Program, Centre for Addiction and Mental Health, 250 College Street, Toronto, ON M5T 1R8, Canada
    Arch Sex Behav 39:304-16. 2010
    ..It therefore seems that the current (i.e., DSM-IV-TR) diagnostic criteria need to be examined with an openness to major changes in the DSM-V...
  21. doi Sex differences in hormonal responses to a social stressor in chronic major depression
    Kevin K Chopra
    Centre for Addiction and Mental Health, Toronto, Ontario, Canada
    Psychoneuroendocrinology 34:1235-41. 2009
    ..The current study evaluated cortisol stress responses to a social challenge in chronic major depressive disorder (CMDD)...
  22. doi Taking culture seriously: ethnolinguistic community perspectives on mental health
    Laura Simich
    Social Equity and Health, Centre for Addiction and Mental Health and University of Toronto, Toronto, Ontario, Canada
    Psychiatr Rehabil J 32:208-14. 2009
    ....
  23. doi Alcohol consumption among Canadians taking benzodiazepines and related drugs
    Scott Veldhuizen
    Health Systems Research and Consulting Unit, Centre for Addiction and Mental Health, Toronto, ON, Canada
    Pharmacoepidemiol Drug Saf 18:203-10. 2009
    ..The combination of BZDs with alcohol increases risk for oversedation, abuse, dependence and accidents. This study examines drinking behaviour among Canadians taking BZDs...
  24. ncbi Prevalence of co-occurring substance use and other mental disorders in the Canadian population
    Brian Rush
    Health Systems Research and Consulting Unit, Centre for Addiction and Mental Health, Toronto, Ontario
    Can J Psychiatry 53:800-9. 2008
    ..This study presents the first national assessment in Canada of the prevalence of co-occurring SUDs and other mental disorders, with attention to differences by substance problem severity, sex, age, and region...
  25. doi Treatment seeking among Ontario problem gamblers: results of a population survey
    Helen Suurvali
    Social, Prevention, and Health Policy Research, Centre for Addiction and Mental Health, Toronto, Ontario, Canada
    Psychiatr Serv 59:1343-6. 2008
    ..This study examined help seeking for gambling concerns among people with different levels of gambling problems...
  26. doi Interpersonal group psychotherapy for comorbid alcohol dependence and non-psychotic psychiatric disorders
    Jan Malat
    Centre for Addiction and Mental Health, Toronto, Ontario, Canada
    Am J Addict 17:402-7. 2008
    ..This study yields preliminary evidence in support of MIGT as a useful treatment approach for an alcohol-dependent population with psychiatric comorbidity...
  27. pmc [Future medications for tobacco and cannabis dependence]
    Bernard Le Foll
    Translational Addiction Research Laboratory, Centre for Addiction and Mental Health, University of Toronto, Toronto, Canada
    Bull Acad Natl Med 192:45-56; discussion 56-7. 2008
    ..These promising approaches warrant clinical trials in the treatment of tobacco and marijuana dependence...
  28. doi D1 receptor antagonist-induced long-term depression in the medial prefrontal cortex of rat, in vivo: an animal model of psychiatric hypofrontality
    Rd Coppa-Hopman
    Department of Psychology, Neuroscience, and Behaviour, McMaster University, Hamilton, Ontario, Canada
    J Psychopharmacol 23:672-85. 2009
    ....
  29. doi Obsessive beliefs in first-degree relatives of patients with OCD: a test of the cognitive vulnerability model
    Neil A Rector
    Anxiety Disorders Clinic, Centre for Addiction and Mental Health, University of Toronto, Toronto, Ontario, Canada
    J Anxiety Disord 23:145-9. 2009
    ..The results are discussed in relation to the developmental context of cognitive-based vulnerabilities for OCD...
  30. doi Role of Special Olympics for mothers of adult athletes with intellectual disability
    Jonathan A Weiss
    Centre for Addiction for Mental Health, Dual Diagnosis Program, Toronto, Ontario, Canada
    Am J Ment Retard 113:241-53. 2008
    ..Taken together, these findings suggest that Special Olympics can function as a formal support for mothers...
  31. ncbi Treatment for hepatitis C virus and cannabis use in illicit drug user patients: implications and questions
    Benedikt Fischer
    Centre for Addictions Research of British Columbia CAR BC, University of Victoria, Victoria, Canada
    Eur J Gastroenterol Hepatol 18:1039-42. 2006
    ....
  32. ncbi Regular health care use by lesbians: a path analysis of predictive factors
    Leah S Steele
    Department of Family and Community Medicine, St Michael s Hospital University of Toronto and the Health Systems Research and Consulting Unit, Centre for Addiction and Mental Health, Toronto, Canada
    Fam Pract 23:631-6. 2006
    ..Lesbians have more health risks than other women but access preventive medical care less frequently...
  33. ncbi The prevalence of road rage: estimates from Ontario
    Reginald G Smart
    Social, Prevention and Health Policy Research, Centre for Addiction and Mental Health, Toronto, ON
    Can J Public Health 94:247-50. 2003
    ..We examine the prevalence and demographic correlates of road rage victimization and perpetration based on a population survey of adults in Ontario...
  34. ncbi Secular trends in self-reported violent activity among Ontario students, 1983-2001
    Angela Paglia
    Centre for Addiction and Mental Health, Population and Life Course Studies, Toronto, ON
    Can J Public Health 94:212-7. 2003
    ..This paper examines secular trends in violence among Ontario students between 1983 and 2001, and variation by sex...
  35. ncbi Evolved mechanisms in depression: the role and interaction of attachment and social rank in depression
    L Sloman
    Leon Sloman, Centre for Addiction and Mental Health, 250 College St, Toronto, Ontario, Canada M5T 1R8
    J Affect Disord 74:107-21. 2003
    ..g., sense of unlovableness, self as inferior and a failure). This focus offers clues as to how these two systems interact and on how to intervene...
  36. ncbi Recent developments in the psychobiology and pharmacotherapy of depression: optimising existing treatments and novel approaches for the future
    P Farvolden
    Centre for Addiction and Mental Health, 250 College Street, Toronto, Ontario, M5T 1R8, Canada
    Expert Opin Investig Drugs 12:65-86. 2003
    ..In order to better understand the neurobiology and treatment response of MDD, it is probable that more sophisticated theory-driven typologies of MDD will have to be developed...
  37. ncbi Patterns of substance use in treatment-seeking problem gamblers: impact on treatment outcomes
    Tony Toneatto
    Clincal Research Department, Center for Addiction and Mental Health, Toronto, Ontario, Canada
    J Clin Psychol 58:853-9. 2002
    ..These findings indicate that gamblers are more likely to be involved with drug and medication use compared to the general population, but that such histories are not associated with gambling treatment outcomes...
  38. ncbi Multiple 5-HT receptors are involved in the effects of acute MDMA treatment: studies on locomotor activity and responding for conditioned reinforcement
    Paul J Fletcher
    Section of Biopsychology, Centre for Addiction and Mental Health, 250 College Street, Toronto, Ontario, Canada, M5T 1R8
    Psychopharmacology (Berl) 162:282-91. 2002
    ..The amphetamine derivative 3,4-methylenedioxymethamphetamine (MDMA, Ecstasy) releases both monoamines...
  39. ncbi The early effects of Ontario's Administrative Driver's Licence Suspension law on driver fatalities with a BAC > 80 mg%
    Robert E Mann
    Social, Prevention and Health Policy Research Department, Centre for Addiction and Mental Health, 33 Russell Street, Toronto, ON, M5S 2S1
    Can J Public Health 93:176-80. 2002
    ..This study evaluates the early effects of Ontario's ADLS law on alcohol-involved driver fatalities...
  40. ncbi Changing patient characteristics with increased methadone maintenance availability
    Bruna Brands
    Centre for Addiction and Mental Health, 33 Russell St Toronto, M5S 2S1, Ontario, Canada
    Drug Alcohol Depend 66:11-20. 2002
    ..the rapid expansion in treatment availability in Ontario on the long-standing MMT program of the Centre for Addiction and Mental Health (CAMH)...
  41. ncbi Using financial incentives to promote shared mental health care
    C S Dewa
    Centre for Addiction and Mental Health, Health Systems Research and Consulting Unit, Department of Psychiatry, University of Toronto, Toronto, Ontario
    Can J Psychiatry 46:488-95. 2001
    ..To consider the most common primary care reimbursement structures, to identify incentives inherent in each, and to discuss how each could be used to encourage a shared-care approach to treating mental disorders at the primary care level...
  42. ncbi Comorbidity of psychiatric and substance use disorders in late adolescence: a cluster analytic approach
    J H Beitchman
    Centre for Addiction and Mental Health, Department of Psychiatry, University of Toronto, Ontario, Canada
    Am J Drug Alcohol Abuse 27:421-40. 2001
    ..Clarification of the developmental progress of the youths in these cluster groups can inform our approach to early intervention and treatment...
  43. ncbi Clomipramine versus haloperidol in the treatment of autistic disorder: a double-blind, placebo-controlled, crossover study
    G Remington
    Centre for Addiction and Mental Health, Clarke Division, Toronto, Ontario, Canada
    J Clin Psychopharmacol 21:440-4. 2001
    ..Clomipramine did not seem more effective on a measure of stereotypy, nor was it better tolerated...
  44. ncbi Personality and the affective disorders: past efforts, current models, and future directions
    R M Bagby
    Section on Personality and Psychopathology, Centre for Addiction and Mental Health, Clarke Site, 250 College Street, Toronto, Ontario, M5T 1R8, Canada
    Curr Psychiatry Rep 2:465-72. 2000
    ..The overall objective is to search for commonalities in past and present models, and to deal with ongoing concerns, in order to point the way for future research in the field...
  45. ncbi The discriminative validity of a phallometric test for pedophilic interests among adolescent sex offenders against children
    M C Seto
    Centre for Addiction and Mental Health, Toronto, Ontario, Canada
    Psychol Assess 12:319-27. 2000
    ..Results suggest phallometric testing can identify pedophilic interests among these adolescent sex offenders...
  46. ncbi Screening for antisocial personality disorder in drug users--a qualitative exploratory study on feasibility
    Benedikt Fischer
    University of Toronto, Toronto, Ontario, Canada
    Int J Methods Psychiatr Res 12:151-6. 2003
    ..Questions were seen as sex-biased. Provision of support to deal with potential emotional problems should be supplied. Potential revision should be considered to include the female perspective in the screen...
  47. ncbi Birth order in the fakafefine
    Kenneth J Zucker
    Child and Adolescent Gender Identity Clinic, Child Psychiatry Program, Center for Addiction and Mental Health Clarke Division, Toronto, Ontario, Canada
    J Sex Marital Ther 29:251-3. 2003
  48. ncbi Amphetamine primes motivation to gamble and gambling-related semantic networks in problem gamblers
    Martin Zack
    Centre for Addiction and Mental Health, Toronto, Ontario, Canada M5S 2S1
    Neuropsychopharmacology 29:195-207. 2004
    ..This study provides experimental evidence that psychostimulant-like neurochemical activation is an important component of gambling addiction...
  49. ncbi Closing the research-practice gap: factors affecting adoption and implementation of a children's mental health program
    Joanna L Henderson
    Child, Youth and Family Program, Centre for Addiction and Mental Health, University of Toronto, Ontario, Canada
    J Clin Child Adolesc Psychol 35:2-12. 2006
    ..Moreover, they suggest that innovation characteristics may be particularly important to adoption, whereas adopter and dissemination characteristics may be more influential in implementation...
  50. ncbi [Willing to undergo hepatitis C treatment in a sample of injection drug users in Toronto, Canada]
    B Fischer
    Centre for Addiction and Mental Health, Toronto, Canada
    Presse Med 34:1209-12. 2005
    ..Little research has been undertaken in order to discover the willingness of IDUs to receive HCV treatment, however...
  51. ncbi Early history of the concept of autogynephilia
    Ray Blanchard
    Law and Mental Health Program, Centre for Addiction and Mental Health College Street Site, 250 College Street, Toronto, Ontario, M5T 1R8, Canada
    Arch Sex Behav 34:439-46. 2005
    ..To fill this terminological and conceptual gap, the writer introduced the term autogynephilia(love of oneself as a woman)...
  52. ncbi Evidence for onset of antipsychotic effects within the first 24 hours of treatment
    Shitij Kapur
    Centre for Addiction and Mental Health, 250 College St, Toronto, Ont, Canada M5R 1T8
    Am J Psychiatry 162:939-46. 2005
    ..Recent research has shown that antipsychotic action begins within the first week. The authors tested the hypothesis that psychosis improves within the first 24 hours of antipsychotic treatment...
  53. ncbi Smoking cessation and lung cancer mortality in a cohort of middle-aged Canadian women
    Bo Zhang
    Ontario Tobacco Research Unit, University of Toronto, Toronto, Canada
    Ann Epidemiol 15:302-9. 2005
    ..To determine the impact of smoking cessation on lung cancer mortality among women...
  54. ncbi Distinguishing bipolar depression, major depression, and schizophrenia with the MMPI-2 clinical and content scales
    R Michael Bagby
    Centre for Addiction and Mental Health, Toronto, Ontario, Canada
    J Pers Assess 84:89-95. 2005
    ..No clinical or content scale proved to be effective in distinguishing patients with bipolar depression from patients with major depression. In general, the content scales outperformed the clinical scales...
  55. ncbi Design and feasibility of a new cognitive-behavioural therapy course using a longitudinal interactive format
    Mark A Lau
    Department of Psychiatry, Centre for Addiction and Mental Health, University of Toronto, Ontario
    Can J Psychiatry 49:696-700. 2004
    ....
  56. ncbi Predicting abuse in adolescent dating relationships over 1 year: the role of child maltreatment and trauma
    David A Wolfe
    Department of Psychiatry, Centre for Addiction and Mental Health, London, ON, Canada
    J Abnorm Psychol 113:406-15. 2004
    ..The importance of longitudinal methodology that separates correlates from predictors is discussed...
  57. pmc Health promotion in the workplace: framing the concept; reviewing the evidence
    M Shain
    Centre for Addiction and Mental Health, 33 Russell St, Toronto, Canada, M5S 2S1
    Occup Environ Med 61:643-8, 585. 2004
  58. ncbi When street sex workers are mothers
    Christine M Sloss
    Department of Psychology, DePaul University, Chicago, Illinois, USA
    Arch Sex Behav 33:329-41. 2004
    ..It is evident from these interviews that street sex workers who are mothers have unique needs and experiences that must be considered by researchers, policy makers, and service providers...
  59. ncbi Glutathione S-transferase is a novel target for mood stabilizing drugs in primary cultured neurons
    Jun Feng Wang
    Centre for Addiction and Mental Health, and Department of Psychiatry, University of Toronto, Ontario, Canada
    J Neurochem 88:1477-84. 2004
    ..The present findings suggest that regulation of GST M1, and possibly GST A4, may mediate the anti-oxidative effects of valproate treatment, and regulation of GST may be involved in the mood stabilizing effect of valproate and lithium...
  60. ncbi Proportion of homosexual men who owe their sexual orientation to fraternal birth order: An estimate based on two national probability samples
    Ray Blanchard
    Department of Psychiatry, University of Toronto, Toronto, Ontario, Canada
    Am J Hum Biol 16:151-7. 2004
    ....
  61. ncbi Only one in three people with alcohol abuse or dependence ever seek treatment
    John A Cunningham
    Centre for Addiction and Mental Health, 33 Russell Street, Toronto, Ontario, Canada M5S 2S1
    Addict Behav 29:221-3. 2004
    ..Respondents' age and severity of alcohol problem (alcohol abuse versus dependence) were significantly associated with addiction treatment attendance...
  62. pmc Birth order and fluctuating asymmetry: a first look
    M L Lalumière
    Mental Health Centre Penetanguishene, Ontario, Canada
    Proc Biol Sci 266:2351-4. 1999
    ....

Research Grants57

  1. Internet-based intervention for problem drinking
    John Cunningham; Fiscal Year: 2007
    ..Participants will be Recruited through an ongoing general population survey conducted for the centre for addiction and mental health (n = 170 after attrition), and will be randomly assigned to be sent a world wide web page internet ..
  2. Ultra-brief intervention for problem drinkers
    John A Cunningham; Fiscal Year: 2010
    ..Secondary hypotheses will test the impact of the intervention on help seeking, and explore the mediating or moderating role of perceived drinking norms, perceived risk and the problem drinker's social reasons for drinking. ..
  3. Enhancing the Prospective Prediction of Psychosis
    Jean Addington; Fiscal Year: 2007
    ..Each site has proven its ability to recruit prodromal patients in a previous collaboration. ..
  4. Stress-induced relapse to alcohol in a rat model
    Dzung Le; Fiscal Year: 2007
    ..We hope that data from our preclinical model will lead to the development of medications for the treatment of alcohol addiction. ..
  5. Role of Serotonin in Stress-Induced Relapse to Alcohol
    Dzung Le; Fiscal Year: 2005
    ..Characterization of the relapse process in our preclinical model may lead to the development of medications for relapse prevention in humans...
  6. Stress-induced relapse to alcohol in a rat model
    ANH DZUNG LE; Fiscal Year: 2010
    ..We hope that data from our preclinical model will lead to the development of medications for the treatment of alcohol addiction. ..
  7. DNA METHYLOME STUDY IN TYPE 1 DIABETES
    ART PETRONIS; Fiscal Year: 2009
    ..This effort may have a major impact on our understanding of autoimmune mechanisms in T1D and lead to new strategies in diagnostics and treatment of the disease. ..
  8. PET IMAGING STUDY OF BRAIN VMAT2 IN HUMAN METHAMPHETAMINE USERS
    STEPHEN JOHN KISH; Fiscal Year: 2010
    ..Results might also help in assessing the validity of a brain imaging tool that has been proposed for use in testing whether new neuroprotective drugs slow down the progression of Parkinson's disease. ..
  9. BRAIN SEROTONIN TRANSPORTER IN ECSTASY AND MDA USERS
    Stephen Kish; Fiscal Year: 2007
    ..More broadly, our data will help define the contribution of different neuroanatomical components of the brain serotonin system to human behavior. ..
  10. Molecular Epigenetic Studies of Major Depression
    ART PETRONIS; Fiscal Year: 2009
    ..controls in both within and between all the listed comparisons. If the null hypotheses cannot be rejected, the study will provide a new perspective on the fundamental issues in MDD and other complex diseases. ..
  11. DNA METHYLOME ANALYSIS IN BIPOLAR DISORDER
    ART PETRONIS; Fiscal Year: 2010
    ..Also, this effort may have a dramatic impact on our understanding of the molecular mechanisms of the disturbed brain and lead to new strategies in diagnostics and treatment of major psychiatric illness. ..
  12. CHOLINERGIC AND OPIATE MECHANISMS IN DRUG REINFORCEMENT
    WILLIAM CORRIGALL; Fiscal Year: 1999
    ..The second strategy in this research is, then, to investigate the mechanisms by which opiates regulate the mesolimbic dopamine systems in cocaine reinforcement. ..
  13. Prevention of Relapse in Recurrent Depression with MBCT
    Zindel Segal; Fiscal Year: 2007
    ....
  14. CHOLINERGIC AND OPIATE MECHANISMS IN DRUG REINFORCEMENT
    Shafiqur Rahman; Fiscal Year: 2002
    ....
  15. Serotonin Modulation in Geriatric Depression
    Gwenn Smith; Fiscal Year: 2006
    ..abstract_text> ..
  16. Monoamiergic Function in Geriatric Psychiatry
    Gwenn Smith; Fiscal Year: 2007
    ..The Independent Scientist Award will enable the candidate to continue to firmly focus her research and mentorship activities in the area of geriatric neuropsychiatry. ..
  17. Optimal Dosing of Antipsychotic Drugs in Late Life
    David Mamo; Fiscal Year: 2010
    ..Studying the extent of antipsychotic drug binding to brain receptors using positron emission tomography (PET) will allow for the prediction of the lowest effective dose required to maintain wellness in older patients. ..
  18. Brain reward system, depression and nicotine dependence
    Usoa Busto; Fiscal Year: 2003
    ..The BRS could become the target for developing new treatments for nicotine dependence and some symptoms of MDD. ..
  19. 3/3-Incomplete Response in Late-Life Depression: Getting to Remission
    Benoit H Mulsant; Fiscal Year: 2010
    ..There are is no evidence-based pharmacotherapy for TRLLD;thus, this study seeks to address a major gap in the evidence base for treating depression. ..
  20. 3/3-Incomplete Response in Late-Life Depression: Getting to Remission
    Benoit Mulsant; Fiscal Year: 2009
    ..There are is no evidence-based pharmacotherapy for TRLLD; thus, this study seeks to address a major gap in the evidence base for treating depression. ..
  21. GERIATRIC DEPRESSION--METHODS FOR EFFECTIVENESS TRIALS
    Benoit Mulsant; Fiscal Year: 2002
    ....
  22. Electroacupuncture for Major Depression: A Pilot Study
    Benoit Mulsant; Fiscal Year: 2004
    ..abstract_text> ..
  23. Acute Pharmacotherapy of Late-Life Mania
    Benoit Mulsant; Fiscal Year: 2007
    ..The sites have a history of successful collaborative research, including demanding geriatric studies. ..
  24. Complex Trials for Severe Geriatric Mood Disorders
    Benoit Mulsant; Fiscal Year: 2007
    ..With the support of this award, additional work proposed in this application will focus on improving recruitment and retention of older minority subjects with severe mood disorders in this and other trials. ..
  25. Acute Pharmacotherapy of Unipolar Psychotic Depression
    Benoit Mulsant; Fiscal Year: 2006
    ..Remitted subjects are also followed during stabilization to determine the stability of remission and predictors of clinical and functional deterioration. ..