Edward J Mills

Summary

Affiliation: Canadian College of Naturopathic Medicine
Country: Canada

Publications

  1. pmc Efficacy of acupuncture for cocaine dependence: a systematic review & meta-analysis
    Edward J Mills
    Department of Clinical Epidemiology, Canadian College of Naturopathic Medicine, North York, Ontario, Canada
    Harm Reduct J 2:4. 2005
  2. pmc LOST to follow-up Information in Trials (LOST-IT): a protocol on the potential impact
    Elie A Akl
    Department of Medicine, State University of New York at Buffalo, Buffalo, USA
    Trials 10:40. 2009
  3. pmc Teaching Evidence-Based Complementary and Alternative Medicine (EBCAM); changing behaviours in the face of reticence: a cross-over trial
    Edward Mills
    Department of Research, The Canadian College of Naturopathic Medicine, North York, Canada
    BMC Med Educ 2:2. 2002
  4. pmc The safety of over-the-counter niacin. A randomized placebo-controlled trial [ISRCTN18054903]
    Edward Mills
    Department of Research, Canadian College of Naturopathic Medicine, North York, Canada
    BMC Clin Pharmacol 3:4. 2003
  5. pmc Health food store recommendations: implications for breast cancer patients
    Edward Mills
    Department of Research, Canadian College of Naturopathic Medicine, North York, Ontario, Canada
    Breast Cancer Res 5:R170-4. 2003
  6. ncbi request reprint Emerging issues associated with HIV patients seeking advice from health food stores
    Edward Mills
    Dept of Research, Canadian College of Naturopathic Medicine, North York, ON
    Can J Public Health 94:363-6. 2003
  7. pmc Impact of federal safety advisories on health food store advice
    Edward Mills
    Department of Research, Canadian College of Naturopathic Medicine, 1255 Sheppard Avenue East, North York, Ontario M2K 1E2, Canada
    J Gen Intern Med 19:269-72. 2004
  8. ncbi request reprint Teaching evidence-based complementary and alternative medicine: 1. A learning structure for clinical decision changes
    Edward J Mills
    Department of Research, The Canadian College of Naturopathic Medicine, North York, Ontario
    J Altern Complement Med 8:207-14. 2002
  9. ncbi request reprint Teaching evidence-based complementary and alternative medicine: 2. A conceptual approach to causation-part 2
    Kumanan Wilson
    Department of Medicine, University of Toronto, Ontario, Canada
    J Altern Complement Med 8:385-9. 2002
  10. ncbi request reprint Teaching evidence-based complementary and alternative medicine: 4. Appraising the evidence for papers on therapy
    Kumanan Wilson
    Department of Medicine, University of Toronto, Ontario, Canada
    J Altern Complement Med 8:673-9. 2002

Collaborators

Detail Information

Publications82

  1. pmc Efficacy of acupuncture for cocaine dependence: a systematic review & meta-analysis
    Edward J Mills
    Department of Clinical Epidemiology, Canadian College of Naturopathic Medicine, North York, Ontario, Canada
    Harm Reduct J 2:4. 2005
    ..However, most trials were hampered by large loss to follow up and the strength of the inference is consequently weakened...
  2. pmc LOST to follow-up Information in Trials (LOST-IT): a protocol on the potential impact
    Elie A Akl
    Department of Medicine, State University of New York at Buffalo, Buffalo, USA
    Trials 10:40. 2009
    ..The secondary objectives are to describe, for published RCTs, (1) the reporting of loss to follow-up information, (2) the analytic methods used for handling loss to follow-up information, and (3) the extent of reported loss to follow-up...
  3. pmc Teaching Evidence-Based Complementary and Alternative Medicine (EBCAM); changing behaviours in the face of reticence: a cross-over trial
    Edward Mills
    Department of Research, The Canadian College of Naturopathic Medicine, North York, Canada
    BMC Med Educ 2:2. 2002
    ..In this study we attempt to determine if a workshop for final year students at a naturopathic college improved their ability to utilize critical appraisal concepts...
  4. pmc The safety of over-the-counter niacin. A randomized placebo-controlled trial [ISRCTN18054903]
    Edward Mills
    Department of Research, Canadian College of Naturopathic Medicine, North York, Canada
    BMC Clin Pharmacol 3:4. 2003
    ..Niacin is widely available over the counter (OTC). We sought to determine the safety of 500 mg immediate release niacin, when healthy individuals use them as directed...
  5. pmc Health food store recommendations: implications for breast cancer patients
    Edward Mills
    Department of Research, Canadian College of Naturopathic Medicine, North York, Ontario, Canada
    Breast Cancer Res 5:R170-4. 2003
    ..Many breast cancer patients use complementary and alternative medicine (CAM). We aimed to determine what advice health food store employees present to individuals seeking treatment options for breast cancer...
  6. ncbi request reprint Emerging issues associated with HIV patients seeking advice from health food stores
    Edward Mills
    Dept of Research, Canadian College of Naturopathic Medicine, North York, ON
    Can J Public Health 94:363-6. 2003
    ..To ascertain the recommendations, training and education of health food store employees and determine how they communicate the costs, benefits and risks associated with natural health products for the HIV/AIDS community...
  7. pmc Impact of federal safety advisories on health food store advice
    Edward Mills
    Department of Research, Canadian College of Naturopathic Medicine, 1255 Sheppard Avenue East, North York, Ontario M2K 1E2, Canada
    J Gen Intern Med 19:269-72. 2004
    ..Twenty-two of 34 stores recommended kava kava, 9 of which mentioned safety concerns. Physicians should be aware that federal advisories may not affect sales of unsafe products...
  8. ncbi request reprint Teaching evidence-based complementary and alternative medicine: 1. A learning structure for clinical decision changes
    Edward J Mills
    Department of Research, The Canadian College of Naturopathic Medicine, North York, Ontario
    J Altern Complement Med 8:207-14. 2002
    ..In order to create communication effectively, an evidence-based approach may provide the common ground required for all schools of thought...
  9. ncbi request reprint Teaching evidence-based complementary and alternative medicine: 2. A conceptual approach to causation-part 2
    Kumanan Wilson
    Department of Medicine, University of Toronto, Ontario, Canada
    J Altern Complement Med 8:385-9. 2002
    ..more likely to lead to disease? Is there evidence from several different studies showing the same association? Does withdrawal of the cause result in loss of the effect? Is there a biologic model that can explain the causal relationship?..
  10. ncbi request reprint Teaching evidence-based complementary and alternative medicine: 4. Appraising the evidence for papers on therapy
    Kumanan Wilson
    Department of Medicine, University of Toronto, Ontario, Canada
    J Altern Complement Med 8:673-9. 2002
    ....
  11. ncbi request reprint Teaching evidence-based complementary and alternative medicine: 5. Interpreting the results of a study on therapy and applying them to a patient
    Kumanan Wilson
    Department of Medicine, University of Toronto, Toronto, Ontario, Canada
    J Altern Complement Med 8:867-73. 2002
    ....
  12. pmc Adherence to HAART: a systematic review of developed and developing nation patient-reported barriers and facilitators
    Edward J Mills
    Centre for International Health and Human Rights Studies, Toronto, Ontario, Canada
    PLoS Med 3:e438. 2006
    ..We systematically reviewed the literature to determine patient-reported barriers and facilitators to adhering to antiretroviral therapy...
  13. pmc Naturopathic care for anxiety: a randomized controlled trial ISRCTN78958974
    Kieran Cooley
    Department of Research and Clinical Epidemiology, The Canadian College of Naturopathic Medicine, Toronto, Canada
    PLoS ONE 4:e6628. 2009
    ..This study sought to explore the effectiveness of naturopathic care on anxiety symptoms using a randomized trial...
  14. pmc Naturopathic care for chronic low back pain: a randomized trial
    Orest Szczurko
    Division of Clinical Epidemiology, Canadian College of Naturopathic Medicine, Toronto, Ontario, Canada
    PLoS ONE 2:e919. 2007
    ..Chronic low back pain represents a substantial cost to employers through benefits coverage and days missed due to incapacity. We sought to explore the effectiveness of Naturopathic care on chronic low back pain...
  15. doi request reprint Male sex and the risk of mortality among individuals enrolled in antiretroviral therapy programs in Africa: a systematic review and meta-analysis
    Eric Druyts
    Faculty of Health Sciences, University of Ottawa, Ottawa, Ontario, Canada
    AIDS 27:417-25. 2013
    ..HIV/AIDS has historically had a sex and gender-focused approach to prevention and care. Some evidence suggests that HIV-positive men have worse treatment outcomes than their women counterparts in Africa...
  16. pmc Cardiovascular events associated with smoking cessation pharmacotherapies: a network meta-analysis
    Edward J Mills
    Stanford Prevention Research Center, Stanford University, Stanford, CA E J M, K T, J J P Faculty of Health Sciences, University of Ottawa, Ottawa, ON, Canada E J M, S E, P W and Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, ON, Canada K T
    Circulation 129:28-41. 2014
    ..We aimed to examine whether the 3 licensed smoking cessation therapies-nicotine replacement therapy, bupropion, and varenicline-were associated with an increased risk of cardiovascular disease events using a network meta-analysis...
  17. doi request reprint Long-term health care interruptions among HIV-positive patients in Uganda
    Edward J Mills
    University of Ottawa, Ottawa, Ontario, Canada
    J Acquir Immune Defic Syndr 63:e23-7. 2013
    ..We examined risk factors for health care interruptions and loss to follow-up within a cohort receiving ART in Uganda...
  18. ncbi request reprint Teaching evidence-based complementary and alternative medicine: 3. Asking the questions and identifying the information
    Kumanan Wilson
    Department of Medicine, University of Toronto, Toronto, Ontario, Canada
    J Altern Complement Med 8:499-506. 2002
    ..This paper suggests practical strategies for successful database searches in support of EBCAM...
  19. doi request reprint CD4(+) T-cell recovery after initiation of antiretroviral therapy in a resource-limited setting: a prospective cohort analysis
    Steve Kanters
    Faculty of Health Sciences, University of Ottawa, Ottawa, ON, Canada
    Antivir Ther 19:31-9. 2014
    ..CD4(+) T-cell count recovery after antiretroviral therapy (ART) initiation is associated with improved health outcomes. It is unknown how the CD4(+) T-cell counts of African HIV patients recover following ART initiation...
  20. pmc Increased mortality among HIV-positive men on antiretroviral therapy: survival differences between sexes explained by late initiation in Uganda
    Steve Kanters
    Faculty of Health Science, Simon Fraser University, Burnaby, BC, Canada Faculty of Health Sciences, University of Ottawa, Ottawa, ON, Canada
    HIV AIDS (Auckl) 5:111-9. 2013
    ..We also specifically examined the role of antenatal services in favoring women's access to HIV care...
  21. doi request reprint Primary prevention of cardiovascular mortality and events with statin treatments: a network meta-analysis involving more than 65,000 patients
    Edward J Mills
    Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario, Canada
    J Am Coll Cardiol 52:1769-81. 2008
    ..This study aimed to evaluate the effectiveness of 3-hydroxy-3-methyl-glutaryl-CoA reductase inhibitors (statins) in primary prevention of cardiovascular events...
  22. ncbi request reprint Teaching evidence-based complementary and alternative medicine: 2. A conceptual approach to causation-part 1
    Kumanan Wilson
    Department of Medicine, University of Toronto, Ontario, Canada
    J Altern Complement Med 8:379-83. 2002
    ....
  23. ncbi request reprint Systematically reviewing qualitative studies complements survey design: an exploratory study of barriers to paediatric immunisations
    Edward J Mills
    Department of Clinical Epidemiology and Biostatistics, McMaster University, Health Science Centre, Hamilton, Ontario, Canada
    J Clin Epidemiol 58:1101-8. 2005
    ..We examined surveys addressing parental barriers to vaccinating children to determine if they comprehensively included themes identified in published qualitative studies...
  24. doi request reprint Comparison of weight loss among named diet programs in overweight and obese adults: a meta-analysis
    Bradley C Johnston
    Hospital for Sick Children Research Institute, Toronto, Ontario, Canada2Institute of Health Policy, Management and Evaluation, University of Toronto, Toronto, Ontario, Canada3Department of Clinical Epidemiology and Biostatistics, McMaster University, Hami
    JAMA 312:923-33. 2014
    ..Many claims have been made regarding the superiority of one diet or another for inducing weight loss. Which diet is best remains unclear...
  25. pmc Micronutrient deficiency and treatment adherence in a randomized controlled trial of micronutrient supplementation in ART-naïve persons with HIV
    Louise Balfour
    CIHR Canadian HIV Trials Network CTN, Vancouver, British Columbia, Canada Division of Infectious Diseases, Department of Medicine, University of Ottawa at The Ottawa Hospital, Ottawa, Ontario, Canada
    PLoS ONE 9:e85607. 2014
    ..The MAINTAIN study is an on-going RCT comparing high-dose micronutrient and anti-oxidant supplementation versus recommended daily allowance (RDA) vitamins in slowing HIV immune deficiency progression in ART-naïve people with HIV infection...
  26. doi request reprint Why the findings of published multiple treatment comparison meta-analyses of biologic treatments for rheumatoid arthritis are different: an overview of recurrent methodological shortcomings
    Kristian Thorlund
    Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario, Canada
    Ann Rheum Dis 72:1524-35. 2013
    ....
  27. pmc Modelling heterogeneity variances in multiple treatment comparison meta-analysis--are informative priors the better solution?
    Kristian Thorlund
    Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, ON, Canada
    BMC Med Res Methodol 13:2. 2013
    ..Relaxing the homogeneous variance assumption may be equally problematic due to reduced precision. To regain good precision, moderately informative variance priors or additional mathematical assumptions may be necessary...
  28. ncbi request reprint How to use an article reporting a multiple treatment comparison meta-analysis
    Edward J Mills
    Faculty of Health Sciences, University of Ottawa, Room 031, Thompson Hall, 35 University Private, Ottawa, ON, K1N 7K4, Canada
    JAMA 308:1246-53. 2012
    ..This article uses the existing Users' Guides format to address study validity, interpretation of results, and application to a patient scenario...
  29. ncbi request reprint The effects of green tea consumption on incidence of breast cancer and recurrence of breast cancer: a systematic review and meta-analysis
    Dugald Seely
    Department of Clinical Epidemiology, Canadian College of Naturopathic Medicine, Toronto, Ontario, Canada
    Integr Cancer Ther 4:144-55. 2005
    ..Green tea is widely used by women for the prevention and treatment of breast cancer. The authors aimed to determine the efficacy of green tea ingestion on the risk of breast cancer development and the risk of breast cancer recurrence...
  30. doi request reprint Stopping randomized trials early for benefit and estimation of treatment effects: systematic review and meta-regression analysis
    Dirk Bassler
    Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario, Canada
    JAMA 303:1180-7. 2010
    ..Theory and simulation suggest that randomized controlled trials (RCTs) stopped early for benefit (truncated RCTs) systematically overestimate treatment effects for the outcome that precipitated early stopping...
  31. ncbi request reprint Adherence to antiretroviral therapy in sub-Saharan Africa and North America: a meta-analysis
    Edward J Mills
    Centre for International Health and Human Rights Studies, Toronto, Ontario, Canada
    JAMA 296:679-90. 2006
    ..Concerns about incomplete adherence among patients living in poverty have been an important consideration in expanding the access to antiretroviral therapy in sub-Saharan Africa...
  32. doi request reprint Life expectancy of persons receiving combination antiretroviral therapy in low-income countries: a cohort analysis from Uganda
    Edward J Mills
    University of Ottawa, Ottawa, Ontario, Canada
    Ann Intern Med 155:209-16. 2011
    ..Little is known about the effect of combination antiretroviral therapy (cART) on life expectancy in sub-Saharan Africa...
  33. doi request reprint Design and methods of the MAINTAIN study: a randomized controlled clinical trial of micronutrient and antioxidant supplementation in untreated HIV infection
    Neera Singhal
    Department of Medicine, University of Ottawa at Ottawa Hospital Research Institute, Ottawa, Ontario, Canada
    Contemp Clin Trials 31:604-11. 2010
    ..We discuss here the study design and methods, often used for evaluation of complementary and adjunctive treatments for health maintenance in HIV infection, which are common interventions...
  34. pmc Traditional Chinese Medicines in the treatment of hepatocellular cancers: a systematic review and meta-analysis
    Ping Wu
    Shanghai Hospital 4, Shanghai, PR China
    J Exp Clin Cancer Res 28:112. 2009
    ..Several Traditional Chinese Medicines (TCM) have been evaluated in clinical trials, but little is known about them outside of China...
  35. ncbi request reprint In vitro analysis of the herbal compound Essiac
    Dugald Seely
    Department of Research and Clinical Epidemiology, The Canadian College of Naturopathic Medicine, Toronto, ON, Canada
    Anticancer Res 27:3875-82. 2007
    ..We aimed to address this deficiency by conducting a series of assays to determine some of the purported activities of Essiac in vitro...
  36. ncbi request reprint Diagnostic accuracy among the allied health professions: commentary on Grace et Al
    Dugald Seely
    Department of Clinical Epidemiology, The Canadian College of Naturopathic Medicine, North York, Ontario, Canada
    J Altern Complement Med 12:701-2. 2006
  37. pmc Prolactin-related adverse events and change in prolactin levels in pediatric patients given antipsychotics for schizophrenia and schizophrenia spectrum disorders: A systematic review
    Eric Druyts
    Faculty of Health Sciences, University of Ottawa, Ottawa, ON, Canada
    BMC Pediatr 16:181. 2016
    ..The purpose of this review is to examine the risk of prolactin-related adverse events in pediatric patients using antipsychotics and to quantify changes in prolactin for this population...
  38. pmc Risk of medication overuse headache across classes of treatments for acute migraine
    Kristian Thorlund
    Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, ON, Canada
    J Headache Pain 17:107. 2016
    ..We therefore aimed to determine whether certain classes of acute migraine drugs are more likely to elicit MOH than others...
  39. ncbi request reprint Disclosure of natural product use to primary care physicians: a cross-sectional survey of naturopathic clinic attendees
    Jason W Busse
    Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario, Canada
    Mayo Clin Proc 80:616-23. 2005
    ..To determine factors that predict disclosure of natural product use by patients to their primary care physicians...
  40. pmc Barriers to the effective treatment and prevention of malaria in Africa: A systematic review of qualitative studies
    David M Maslove
    Department of Medicine, University of Toronto, Toronto, Ontario, Canada
    BMC Int Health Hum Rights 9:26. 2009
    ....
  41. doi request reprint Comparisons of high-dose and combination nicotine replacement therapy, varenicline, and bupropion for smoking cessation: a systematic review and multiple treatment meta-analysis
    Edward J Mills
    Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario, Canada
    Ann Med 44:588-97. 2012
    ..This review compared the effect of high-dose nicotine replacement therapy (NRT) and combinations of NRT for increasing smoking abstinence rates compared to standard-dose NRT patch, varenicline, and bupropion on smoking abstinence...
  42. doi request reprint What drives the comparative effectiveness of biologics vs. methotrexate in rheumatoid arthritis? Meta-regression and graphical inspection of suspected clinical factors
    Steve Kanters
    Department of Population and Public Health, University of British Columbia, Vancouver, BC, Faculty of Medicine, University of Ottawa, Ottawa, ON, Canada, Stanford Prevention Research Center, Stanford University, Palo Alto, CA, USA and Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, ON, Canada Department of Population and Public Health, University of British Columbia, Vancouver, BC, Faculty of Medicine, University of Ottawa, Ottawa, ON, Canada, Stanford Prevention Research Center, Stanford University, Palo Alto, CA, USA and Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, ON, Canada
    Rheumatology (Oxford) 53:1264-73. 2014
    ..The aim of this study was to explore which clinical factors and patient characteristics are associated with the magnitude of comparative efficacy between biologics vs. MTX in RA patients with inadequate response to MTX...
  43. doi request reprint Calculating additive treatment effects from multiple randomized trials provides useful estimates of combination therapies
    Edward J Mills
    Faculty of Health Sciences, University of Ottawa, 43 Templeton Street, Ottawa, Ontario, Canada
    J Clin Epidemiol 65:1282-8. 2012
    ..We discuss here the prerequisites and methods of applying additivity assumptions in synthesizing the evidence from randomized trials and multiple treatment meta-analyses...
  44. ncbi request reprint Epidemiology and reporting of randomized trials employing re-randomization of patient groups: a systematic survey
    Edward J Mills
    Department of Clinical Epidemiology and Biostatistics, McMaster University, 1200 Main Street West, Hamilton, Ontario, Canada
    Contemp Clin Trials 28:268-75. 2007
    ....
  45. ncbi request reprint The quality of randomized trial reporting in leading medical journals since the revised CONSORT statement
    Edward J Mills
    Department of Clinical Epidemiology and Biostatistics, Faculty of Health Sciences, McMaster University, HSC 2C12, 1200 Main Street West, Hamilton, ON, Canada, L8N 3Z5
    Contemp Clin Trials 26:480-7. 2005
    ..Although reporting of some CONSORT recommendations is high, reporting of several essential recommendations remains suboptimal. Authors need to comply with and journals need to enforce reporting of the revised CONSORT recommendations...
  46. pmc Anti-tumor necrosis factor (TNF) drugs for the treatment of psoriatic arthritis: an indirect comparison meta-analysis
    Kristian Thorlund
    Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario, Canada
    Biologics 6:417-27. 2012
    ....
  47. doi request reprint Low-dose aspirin and cancer mortality: a meta-analysis of randomized trials
    Edward J Mills
    Faculty of Health Sciences, University of Ottawa, Ontario, Canada
    Am J Med 125:560-7. 2012
    ..We aimed to determine whether cancer mortality also is reduced by low-dose aspirin in the shorter term...
  48. doi request reprint Naturopathic treatment of rotator cuff tendinitis among Canadian postal workers: a randomized controlled trial
    Orest Szczurko
    Canadian College of Naturopathic Medicine, Toronto, Ontario, Canada
    Arthritis Rheum 61:1037-45. 2009
    ..To explore the effectiveness of naturopathic care (NC) on rotator cuff tendinitis using a prospective randomized clinical trial design...
  49. pmc EDTA chelation therapy for cardiovascular disease: a systematic review
    Dugald M R Seely
    Canadian College of Naturopathic Medicine, Toronto, Canada
    BMC Cardiovasc Disord 5:32. 2005
    ..To address this issue we conducted a systematic review to evaluate the best available evidence for the use of EDTA chelation therapy in the treatment of cardiovascular disease...
  50. pmc Association between change in high density lipoprotein cholesterol and cardiovascular disease morbidity and mortality: systematic review and meta-regression analysis
    Matthias Briel
    Department of Clinical Epidemiology and Biostatistics, McMaster University, 1200 Main Street West, Hamilton, ON, Canada
    BMJ 338:b92. 2009
    ....
  51. pmc In the era of systematic reviews, does the size of an individual trial still matter
    Gordon H Guyatt
    Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario, Canada
    PLoS Med 5:e4. 2008
    ..Others point out that small trials can still be potentially misleading...
  52. pmc Attitudes towards fibromyalgia: a survey of Canadian chiropractic, naturopathic, physical therapy and occupational therapy students
    Jason W Busse
    Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario, Canada
    BMC Complement Altern Med 8:24. 2008
    ....
  53. ncbi request reprint Characteristics of pediatric and adolescent patients attending a naturopathic college clinic in Canada
    Kumanan Wilson
    Department of Medicine, University of Toronto, Toronto, Ontario, Canada
    Pediatrics 115:e338-43. 2005
    ..We also determined factors associated with the use of CAM products and vaccination status...
  54. ncbi request reprint Closing comment: Evidence-based complementary and alternative medicine: is it a viable concept?
    Kumanan Wilson
    Department of Medicine, University of Toronto, Toronto, Ontario, Canada
    J Altern Complement Med 8:875-6. 2002
  55. pmc The Cameroon Mobile Phone SMS (CAMPS) trial: a randomized trial of text messaging versus usual care for adherence to antiretroviral therapy
    Lawrence Mbuagbaw
    Centre for the Development of Best Practices in Health CDBPH, Yaounde Central Hospital, Yaounde, Centre, Cameroon
    PLoS ONE 7:e46909. 2012
    ..This trial investigates the use of motivational mobile phone text messages (SMS) to improve adherence to antiretroviral therapy (ART) over six months...
  56. pmc Differences in clinical outcomes among hepatitis C genotype 1-infected patients treated with peginterferon alpha-2a or peginterferon alpha-2b plus ribavirin: a meta-analysis
    Eric Druyts
    Faculty of Health Sciences, University of Ottawa, Ottawa, ON, Canada
    Clin Exp Gastroenterol 5:11-21. 2012
    ....
  57. doi request reprint Safety of task-shifting for male medical circumcision: a systematic review and meta-analysis
    Nathan Ford
    Centre for Infectious Disease Epidemiology and Research, University of Cape Town, Cape Town, South Africa
    AIDS 26:559-66. 2012
    ..We undertook a systematic review and meta-analysis to review the safety of task-shifting for circumcision in Africa...
  58. pmc Multiple treatment comparison meta-analyses: a step forward into complexity
    Edward J Mills
    Faculty of Health Sciences, University of Ottawa, Ottawa, ON, Canada
    Clin Epidemiol 3:193-202. 2011
    ..We conclude that MTC meta-analysis is a useful tool in the context of comparative effectiveness and requires further study, as its utility and transparency will likely predict its uptake by the research and clinical community...
  59. ncbi request reprint Safety and efficacy of panax ginseng during pregnancy and lactation
    Dugald Seely
    Department of Research and Clinical Epidemiology, The Canadian College of Naturopathic Medicine, Toronto, Canada
    Can J Clin Pharmacol 15:e87-94. 2008
    ..This is one article in a series that systematically reviews the evidence for herbs commonly used during pregnancy and lactation...
  60. ncbi request reprint Impact of African herbal medicines on antiretroviral metabolism
    Edward Mills
    Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario, Canada
    AIDS 19:95-7. 2005
    ..Initiating policies to provide herbal medicines with antiretroviral agents may put patients at risk of treatment failure, viral resistance or drug toxicity...
  61. ncbi request reprint Safety and efficacy of black cohosh (Cimicifuga racemosa) during pregnancy and lactation
    Jean Jacques Dugoua
    Department of Clinical Epidemiology, Canadian College of Naturopathic Medicine, Toronto, Canada
    Can J Clin Pharmacol 13:e257-61. 2006
    ..This is one article in a series that systematically reviews the evidence for commonly used herbs during pregnancy and lactation...
  62. ncbi request reprint Milk thistle and indinavir: a randomized controlled pharmacokinetics study and meta-analysis
    Edward Mills
    Faculty of Health Sciences, Clinical Epidemiology and Biostatistics, McMaster University, HSC 2C12, 1200 Main Street West, Hamilton, ON, L8N 3Z5, Canada
    Eur J Clin Pharmacol 61:1-7. 2005
    ..To determine whether ingestion of milk thistle affects the pharmacokinetics of indinavir...
  63. ncbi request reprint An in vivo analysis of the herbal compound essiac
    Blair J N Leonard
    Faculty of Medicine, University of Toronto, Toronto, ON, Canada
    Anticancer Res 26:3057-63. 2006
    ..Despite its relatively widespread use, there are no peer-reviewed published reports of in vivo studies regarding the use of this compound...
  64. ncbi request reprint Safety and efficacy of St. John's wort (hypericum) during pregnancy and lactation
    Jean Jacques Dugoua
    Department of Clinical Epidemiology, Canadian College of Naturopathic Medicine, Toronto, Canada
    Can J Clin Pharmacol 13:e268-76. 2006
    ..This is one article in a series that systematically reviews the evidence for commonly used herbs during pregnancy and lactation...
  65. ncbi request reprint Randomized trials stopped early for harm in HIV/AIDS: a systematic survey
    Edward Mills
    Centre for International Health and Human Rights Studies, North York, Ontario, Canada
    HIV Clin Trials 7:24-33. 2006
    ..We assessed the prevalence of randomized clinical trials (RCTs) stopped early for harm in HIV/AIDS and determined the quality of reporting of methods to inform the decision to stop the trial...
  66. ncbi request reprint Natural health product-drug interactions: a systematic review of clinical trials
    Edward Mills
    Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario, Canada
    Ther Drug Monit 27:549-57. 2005
    ..With the exception of St. John wort, clinicians and the public do not have information that permits strong inferences about interactions between NHPs and conventional medications...
  67. pmc Enrolling women into HIV preventive vaccine trials: an ethical imperative but a logistical challenge
    Edward Mills
    Centre for International Health and Human Rights Studies, Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario, Canada
    PLoS Med 3:e94. 2006
  68. ncbi request reprint Safety and efficacy of ginkgo (Ginkgo biloba) during pregnancy and lactation
    Jean Jacques Dugoua
    Department of Clinical Epidemiology, Canadian College of Naturopathic Medicine, Toronto, Canada
    Can J Clin Pharmacol 13:e277-84. 2006
    ..This is one article in a series that systematically reviews the evidence for commonly used herbs during pregnancy and lactation...
  69. ncbi request reprint Mitigation of antiretroviral-induced hyperlipidemia by hepatitis C virus co-infection
    Curtis L Cooper
    Division of Infectious Diseases, The Ottawa Hospital, University of Ottawa, Ottawa, Ontario, Canada
    AIDS 21:71-6. 2007
    ..Hyperlipidemia is a recognized complication of HIV antiretroviral therapy. The interactions between HIV, hepatitis C virus (HCV), antiretroviral agents and lipids are not well understood...
  70. ncbi request reprint Introducing evidence-based complementary and alternative medicine: answering the challenge
    Kumanan Wilson
    J Altern Complement Med 8:103-5. 2002
  71. ncbi request reprint Randomized controlled trials in long-term care residents with dementia: a systematic review
    Edward J Mills
    The University of Oxford
    J Am Med Dir Assoc 4:302-7. 2003
    ..To evaluate the quality of reporting of randomized controlled trials for pharmacologic interventions in long-term care residents with dementia...
  72. pmc The abandoned trials of pre-exposure prophylaxis for HIV: what went wrong?
    Jerome A Singh
    Centre for the AIDS Programme of Research, South Africa
    PLoS Med 2:e234. 2005
  73. pmc Problems with use of composite end points in cardiovascular trials: systematic review of randomised controlled trials
    Ignacio Ferreira-Gonzalez
    Departament de Medicina, Universitat Autonoma de Barcelona, and Hospital Vall d Hebron, Barcelona 08035, Spain
    BMJ 334:786. 2007
    ....
  74. doi request reprint HIV/AIDS in African militaries: an ecological analysis
    Oumar Ba
    Faculty of Health Sciences, Simon Fraser University, Vancouver, Canada
    Med Confl Surviv 24:88-100. 2008
    ..4). Population levels predicted military prevalence rates (P < or = 0.001). HIV/AIDS prevalence rates in most African militaries are significantly elevated compared to their host communities...
  75. ncbi request reprint Cost-effectiveness of naturopathic care for chronic low back pain
    Patricia M Herman
    Department of Psychology, University of Arizona, Tucson, Arizona, USA
    Altern Ther Health Med 14:32-9. 2008
    ....
  76. ncbi request reprint The impact of conflict on HIV/AIDS in sub-Saharan Africa
    Edward J Mills
    Centre for International Health and Human Rights Studies, Toronto, Canada
    Int J STD AIDS 17:713-7. 2006
    ..We examine the complexity of monitoring HIV/AIDS in conflict settings. We argue that increased efforts are needed to protect vulnerable populations and design health-delivery systems that are sustainable in settings of conflict...
  77. pmc Designing research in vulnerable populations: lessons from HIV prevention trials that stopped early
    Edward J Mills
    Department of Clinical Epidemiology and Biostatistics, McMaster University, HSC 2C12, 1200 Main Street West, Hamilton, ON, Canada L8N 3Z5
    BMJ 331:1403-6. 2005
  78. ncbi request reprint A wake-up call for global access to salvage HIV drug regimens
    Edward J Mills
    British Columbia Centre for Excellence in HIV AIDS, Vancouver, BC, Canada
    Lancet 370:1885-7. 2007
  79. ncbi request reprint In vitro evaluation of human cytochrome P450 and P-glycoprotein-mediated metabolism of some phytochemicals in extracts and formulations of African potato
    Vipin D P Nair
    Division of Pharmaceutics, Faculty of Pharmacy, Rhodes University, Grahamstown, South Africa
    Phytomedicine 14:498-507. 2007
    ..Appropriate measures are therefore necessary to explore the possibility of such in vitro-in vivo correlations...
  80. ncbi request reprint Changing attitudes towards polio vaccination: a randomized trial of an evidence-based presentation versus a presentation from a polio survivor
    Kumanan Wilson
    Department of Medicine, University of Toronto, Canada
    Vaccine 23:3010-5. 2005
    ..These findings suggest that confronting deeply held beliefs regarding vaccination may paradoxically strengthen these belief systems...
  81. ncbi request reprint HIV infection as a weapon of war
    Edward J Mills
    Lancet Infect Dis 6:752-3. 2006
  82. ncbi request reprint Simple, effective interventions are key to improving adherence in marginalized populations
    Edward J Mills
    Clin Infect Dis 45:916-7. 2007